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Medication-Assisted Treatment (MAT) Centers

Medication-Assisted Treatment (MAT) combines FDA-approved medications with counseling and behavioral therapies for comprehensive addiction care. MAT is the gold standard for opioid and alcohol use disorders, significantly reducing overdose deaths and improving treatment outcomes.

Found 201 treatment centers offering medication-assisted treatment (mat) across the United States.

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Showing 12 of 201 medication-assisted treatment (mat) treatment centers

TrueNorth Treatment Center

TrueNorth Treatment Center in Owensboro, KY, offers comprehensive substance use treatment and transitional housing services. This facility provides specialized care for individuals with co-occurring substance use and serious mental health illnesses. With programs tailored for adults and children, TrueNorth offers intensive outpatient treatment and outpatient methadone/buprenorphine treatment. The center utilizes 12-step facilitation, anger management, and brief intervention approaches to support recovery. Special programs for adolescents, adult men, and women are available. TrueNorth Treatment Center caters to adults and seniors of all genders, ensuring quality care and support for all individuals seeking rehabilitation services.

VOA Recovery
Louisville, KY

Located in Louisville, KY, VOA Recovery specializes in providing rehabilitation services for adult women facing challenges with substance use disorders and concurrent severe mental health issues. The center offers a range of treatment options, including long-term, short-term, and 24-hour residential programs, all based on proven methodologies such as 12-step facilitation, cognitive behavioral therapy, and the Matrix Model. VOA Recovery particularly emphasizes support for clients who have endured intimate partner violence, domestic abuse, and sexual trauma, customizing their programs to suit the distinct needs of every individual. Women of all ages, including seniors and young adults, can find a nurturing and secure space, benefiting from the exceptional care and tailored services provided at this facility.

VOA Recovery
Louisville, KY

Situated in Louisville, KY, VOA Recovery delivers an all-encompassing treatment program for adult males dealing with substance use issues. This center is particularly adept at addressing co-occurring disorders alongside significant mental health challenges in adults, as well as critical emotional difficulties in younger individuals. Emphasizing both long-term and short-term residential options, VOA Recovery employs research-backed methods such as 12-step programs, cognitive behavioral therapy, and the Matrix Model. Special initiatives are designed for adult men, particularly those with experiences of intimate partner violence, domestic abuse, or sexual trauma. Catering to adults, seniors, and young adults alike, this facility ensures that care is customized to meet the unique requirements of its male clientele.

Volunteers of America Mid States

Situated in Louisville, KY, Volunteers of America Mid States focuses on treating substance use issues and co-occurring disorders in both adults and children. The center features various programs, including long-term, short-term, and 24-hour residential care, employing evidence-based strategies like 12-step facilitation, cognitive behavioral therapy, and the Matrix Model. Special programs are available for adult women, as well as those who have experienced intimate partner violence, domestic violence, and sexual abuse. By prioritizing the needs of adult, senior, and young adult women, the facility ensures a nurturing and secure atmosphere conducive to healing and recovery. Discover exceptional support and tailored treatment options at Volunteers of America Mid States.

VOA Addiction Recovery Services

VOA Addiction Recovery Services, located in Louisville, KY, delivers an extensive array of treatment options for substance use disorders, specifically designed for adult women, older adults, and young individuals grappling with severe mental health complications. The center offers a variety of programs, including intensive outpatient, long-term residential, and traditional outpatient services, employing strategies such as 12-step support, anger management techniques, and short intervention methods. Tailored programs are available for those who have faced intimate partner violence, domestic abuse, and sexual trauma. Committed to providing exceptional care, this center aims to assist individuals in overcoming addiction and mental health difficulties within a nurturing environment.

Ultimate Treatment Center

At Ashland, KY's Ultimate Treatment Center, we provide thorough addiction rehabilitation. Our services include detox and drug/alcohol treatment via intensive outpatient, standard outpatient, and outpatient detox options. We employ methods such as anger management, brief intervention, and cognitive behavioral therapy, serving adults and young adults of any gender. Specialized support is available for pregnant/postpartum individuals and veterans. Prioritizing personalized attention and proven techniques, our center is dedicated to aiding each person's path to lasting sobriety.

Spero Health
Somerset, KY

Spero Health in Somerset, KY, delivers specialized outpatient services for adults and young adults grappling with substance use disorders. The center is dedicated to providing high-quality, individualized care, including distinct programs for adult men and women, and for those affected by intimate partner or domestic violence. Their therapeutic framework encompasses strategies such as anger management, brief intervention, and cognitive behavioral therapy. Spero Health provides outpatient treatment utilizing methadone, buprenorphine, or naltrexone, in addition to general outpatient services. Their approach features gender-specific programming for both male and female clients, ensuring that each person receives support aligned with their specific circumstances.

Stepworks of Nicholasville

Situated in Nicholasville, KY, Stepworks of Nicholasville delivers a wide range of addiction recovery services for both adults and young individuals. The center is adept at handling detoxification, substance abuse treatment, and mental health issues arising simultaneously. Prioritizing exceptional care, Stepworks offers inpatient detox and treatment with around-the-clock support. The facility employs diverse methods including 12-step programs, anger management, and short interventions to customize care for each person. Additionally, Stepworks of Nicholasville features tailored programs specifically for adult women, those who have undergone sexual trauma, and individuals dealing with past traumatic experiences. With a welcoming atmosphere for both men and women, this center supports individuals on their journey to recovery.

Windows of Discovery

Windows of Discovery, located in Lexington, KY, delivers a wide range of treatment services for individuals struggling with substance use, particularly those facing concurrent serious mental health issues or emotional challenges. The facility features both intensive outpatient and standard outpatient programs, incorporating therapies such as methadone/buprenorphine assistance. Emphasizing 12-step support, anger management techniques, and short-term interventions, this center serves adults and young adults from all backgrounds. Tailored programs also focus on issues such as intimate partner and domestic violence, sexual trauma, and related experiences. Clients can anticipate a supportive environment paired with scientifically-supported treatment methods to aid their recovery process.

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Volunteers of America Mid States in Manchester, KY, is a dedicated facility providing extensive rehabilitation for adult women dealing with substance use disorders and co-occurring severe mental health challenges. They offer a range of residential programs including long-term, short-term, and 24-hour care, employing proven therapeutic methods like 12-step facilitation, cognitive behavioral therapy, and the Matrix Model. The center has particular expertise in assisting individuals with histories of intimate partner violence, domestic violence, and sexual abuse. Serving adults, seniors, and young adults, their services are tailored for women's unique needs. Volunteers of America Mid States is committed to delivering exceptional, personalized support throughout the recovery process.

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Situated in London, KY, Windows of Discovery delivers extensive treatment for substance use issues in both adults and young adults. The center focuses on managing co-occurring disorders related to substance use alongside significant mental health challenges in adults, or serious emotional issues in children. Offering a variety of services such as intensive outpatient programs, outpatient therapy, and outpatient treatments with methadone/buprenorphine or naltrexone, the facility emphasizes personalized care through methods like 12-step support, anger management, and brief interventions. Specialized programs are also available for those who have faced trauma, sexual abuse, intimate partner violence, or domestic violence. Windows of Discovery serves both male and female clients, ensuring that treatment is customized to meet individual requirements.

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Windows of Discovery Inc, located in Somerset, KY, provides both intensive outpatient and outpatient rehabilitation for adults and young adults dealing with substance use issues. The center is specifically equipped to handle cases involving co-occurring substance use disorders alongside significant mental health conditions or emotional challenges. They employ a variety of therapeutic strategies, including 12-step programs, anger management techniques, and brief intervention therapy. Special programs are designed for individuals who have faced intimate partner violence, domestic abuse, sexual trauma, and other forms of trauma. With an emphasis on tailored care, the facility accommodates male and female clients looking for well-rounded recovery support in a nurturing atmosphere.

Frequently Asked Questions

About Medication-Assisted Treatment (MAT)

Medication-Assisted Treatment (MAT) represents the gold standard for treating opioid and alcohol use disorders. By combining FDA-approved medications with counseling and behavioral therapies, MAT addresses both the biological and psychological aspects of addiction. Research consistently demonstrates that MAT reduces overdose deaths by more than 50%, improves treatment retention, and supports long-term recovery.

MAT Medications for Opioid Use Disorder

Three FDA-approved medications treat opioid addiction:

  • Methadone: Full opioid agonist eliminating withdrawal and cravings; administered daily at certified opioid treatment programs (OTPs). Longest track record with extensive research supporting effectiveness.
  • Buprenorphine (Suboxone, Sublocade): Partial opioid agonist with ceiling effect, reducing abuse potential; prescribed by certified physicians in office settings or as monthly injection. Offers greater flexibility and privacy.
  • Naltrexone (Vivitrol): Opioid antagonist blocking opioid effects; requires complete detox before starting; available as daily pill or monthly injection. Best for motivated individuals after detox completion.

MAT for Alcohol Use Disorder

FDA-approved medications for alcohol addiction:

  • Naltrexone: Reduces cravings and blocks rewarding effects of alcohol; available as daily pill or monthly injection
  • Acamprosate (Campral): Helps restore brain chemistry balance; reduces cravings and supports abstinence
  • Disulfiram (Antabuse): Causes unpleasant reaction if alcohol consumed; provides deterrent for impulsive drinking

Comprehensive Treatment Approach

MAT is never medication alone. Quality programs integrate counseling, behavioral therapies, case management, recovery support services, treatment for co-occurring conditions, and peer support. The medication component allows individuals to engage fully in therapy and recovery activities by eliminating withdrawal, cravings, and physiological barriers to recovery.

Addressing Stigma and Misconceptions

MAT faces unfortunate stigma, with some viewing it as "replacing one drug with another." This is false. MAT medications are prescribed at stable therapeutic doses, don't produce euphoria, allow normal functioning, and are medicine treating a medical condition. Research overwhelming supports MAT as most effective treatment for opioid use disorder. Organizations like SAMHSA, NIDA, and medical professional societies strongly endorse MAT.

Finding MAT Treatment

Look for programs offering multiple MAT medication options, addiction medicine physicians, comprehensive counseling services, individualized treatment planning, support for long-term medication management, and evidence-based behavioral therapies. Our directory helps locate opioid treatment centers and programs offering MAT.

MAT resources and information:

Find Medication-Assisted Treatment (MAT) by State

Browse medication-assisted treatment (mat) programs in states with the most treatment options:

Medically ReviewedUpdated: February 2026
Sources:SAMHSANIDACDC

Need immediate help? Call SAMHSA: 1-800-662-4357 (24/7, free)