Medication-Assisted Treatment (MAT) Centers
Medication-Assisted Treatment (MAT) combines FDA-approved medications with counseling and behavioral therapies for comprehensive addiction care. MAT is the gold standard for opioid and alcohol use disorders, significantly reducing overdose deaths and improving treatment outcomes.
Found 24 treatment centers offering medication-assisted treatment (mat) across the United States.
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Showing 3 of 24 medication-assisted treatment (mat) treatment centers

Situated in San Juan, PR, the VA Caribbean Healthcare System provides an array of rehabilitation services aimed at helping adults and young adults facing challenges with substance use and concurrent mental health issues. The center features tailored programs for active duty members, female adults, and individuals who have experienced intimate partner violence. Offering inpatient detoxification and treatment, it implements methods like anger management, brief intervention, and cognitive behavioral therapy. Focused on personalized care, this center serves both men and women, ensuring top-notch treatment to foster recovery and well-being.

In San Juan, PR, Tratamiento Residencial is a long-term residential treatment center serving adult women who are struggling with substance use disorders alongside significant emotional health challenges. The center features tailored programs for active duty military members, those impacted by intimate partner violence, and survivors of domestic violence. Their therapeutic approaches include 12-step facilitation, anger management techniques, and brief interventions, designed for adults, seniors, and young adults. By providing a secure and nurturing setting specifically for women, Tratamiento Residencial delivers individualized and impactful care for individuals on their path to recovery.

Hogar Santisima Trinidad is situated in Toa Alta, PR, and specializes in providing inpatient detoxification and treatment services specifically for adult men facing substance use challenges. The center emphasizes a holistic approach to care, incorporating methods such as 12-step programs, anger management, and short-term interventions. There are tailored programs for adult men who have gone through experiences of intimate partner violence, domestic violence, and trauma. With an emphasis on delivering personalized and effective rehabilitation for adult, senior, and young adult males, this facility is dedicated to supporting individuals on their journey towards recovery from substance addiction.
Frequently Asked Questions
About Medication-Assisted Treatment (MAT)
Medication-Assisted Treatment (MAT) represents the gold standard for treating opioid and alcohol use disorders. By combining FDA-approved medications with counseling and behavioral therapies, MAT addresses both the biological and psychological aspects of addiction. Research consistently demonstrates that MAT reduces overdose deaths by more than 50%, improves treatment retention, and supports long-term recovery.
MAT Medications for Opioid Use Disorder
Three FDA-approved medications treat opioid addiction:
- Methadone: Full opioid agonist eliminating withdrawal and cravings; administered daily at certified opioid treatment programs (OTPs). Longest track record with extensive research supporting effectiveness.
- Buprenorphine (Suboxone, Sublocade): Partial opioid agonist with ceiling effect, reducing abuse potential; prescribed by certified physicians in office settings or as monthly injection. Offers greater flexibility and privacy.
- Naltrexone (Vivitrol): Opioid antagonist blocking opioid effects; requires complete detox before starting; available as daily pill or monthly injection. Best for motivated individuals after detox completion.
MAT for Alcohol Use Disorder
FDA-approved medications for alcohol addiction:
- Naltrexone: Reduces cravings and blocks rewarding effects of alcohol; available as daily pill or monthly injection
- Acamprosate (Campral): Helps restore brain chemistry balance; reduces cravings and supports abstinence
- Disulfiram (Antabuse): Causes unpleasant reaction if alcohol consumed; provides deterrent for impulsive drinking
Comprehensive Treatment Approach
MAT is never medication alone. Quality programs integrate counseling, behavioral therapies, case management, recovery support services, treatment for co-occurring conditions, and peer support. The medication component allows individuals to engage fully in therapy and recovery activities by eliminating withdrawal, cravings, and physiological barriers to recovery.
Addressing Stigma and Misconceptions
MAT faces unfortunate stigma, with some viewing it as "replacing one drug with another." This is false. MAT medications are prescribed at stable therapeutic doses, don't produce euphoria, allow normal functioning, and are medicine treating a medical condition. Research overwhelming supports MAT as most effective treatment for opioid use disorder. Organizations like SAMHSA, NIDA, and medical professional societies strongly endorse MAT.
Finding MAT Treatment
Look for programs offering multiple MAT medication options, addiction medicine physicians, comprehensive counseling services, individualized treatment planning, support for long-term medication management, and evidence-based behavioral therapies. Our directory helps locate opioid treatment centers and programs offering MAT.
MAT resources and information:
Browse medication-assisted treatment (mat) programs in states with the most treatment options:
Levels of Care
Need immediate help? Call SAMHSA: 1-800-662-4357 (24/7, free)