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Medically Reviewed Content
Updated: May 2026
Sources: SAMHSA, NIDA

Bipolar Disorder & Addiction Treatment Centers

Bipolar disorder and substance use disorders require specialized integrated treatment. Connect with centers offering mood stabilization, medication management, and comprehensive dual diagnosis care.

Found 7,770 rehab centers specializing in bipolar disorder across the United States.

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Region 8 Mental Health Services

Region 8 Mental Health Services located in Canton, MS, provides outpatient treatment for adults struggling with substance use alongside significant mental health conditions, as well as support for emotionally disturbed children. Emphasizing techniques such as 12-step facilitation, anger management, and brief interventions, this center serves active duty military members, young people, and adult males. Catering to all genders among adults and seniors, Region 8 Mental Health Services adopts a holistic method for rehabilitation. Their tailored programs and personalized treatment strategies reflect their dedication to delivering high-quality care to individuals facing addiction and mental health issues.

Regional Health Systems
East Chicago, IN

Regional Health Systems, situated in East Chicago, Indiana, delivers extensive care for adults and older adults facing challenges with substance abuse and co-occurring psychological issues. They offer robust outpatient treatment, detox programs, and individualized outpatient support. The center features distinct programs for expectant/new mothers and those with dual diagnoses, utilizing proven methods like 12-step guidance and emotional regulation techniques. Regional Health Systems is dedicated to providing high-quality services to all patients, men and women alike, prioritizing sustainable recovery through customized plans.

Region IV MHS
Corinth, MS

Region IV MHS in Corinth, MS, provides extensive support for recovery and sober living. This facility is dedicated to addressing dual diagnoses involving substance abuse and significant mental health challenges for adults, along with emotional issues in younger individuals. They offer various residential options, including extended stays, shorter durations, and round-the-clock care, utilizing methods like 12-step program integration, emotional regulation training, and concise support strategies. Region IV MHS supports adult men and women, including those with histories of trauma. Serving a broad age range from adults to young adults, they provide distinct programs for both men and women. Discover personalized treatment and effective recovery pathways at this center.

Regis House
Miami, FL

Regis House, situated in Miami, FL, delivers extensive care for individuals battling substance misuse, with a particular focus on those experiencing co-occurring mental health issues and children with significant emotional difficulties. The facility offers structured intensive outpatient, standard outpatient, and flexible outpatient treatment options, all customized to meet each person's unique requirements. Key therapeutic approaches employed at Regis House include anger management techniques, brief intervention strategies, and cognitive behavioral therapy. The center also provides specialized care for teenagers, adult men, and adult women, addressing the distinct needs of various age and gender groups. Serving a broad spectrum of clients, from adults to seniors of all genders, Regis House is dedicated to providing exceptional treatment and encouragement to those on their journey toward recovery from addiction and mental health concerns.

Regional Medical Center at Lubec

The Regional Medical Center at Lubec, situated in Lubec, ME, provides extensive outpatient services for adults managing substance use disorders alongside significant mental health conditions or emotional challenges. Their expertise includes anger management, brief intervention techniques, and cognitive behavioral therapy. The center caters to specific groups such as active duty military, teenagers, and adult men. They offer high-quality care to adults and older adults of all genders, utilizing outpatient medication-assisted treatments like methadone, buprenorphine, or naltrexone. The Regional Medical Center at Lubec is committed to personalized care plans and specialized interventions to support individuals on their journey to sustained wellness.

Region 4 Desoto
Hernando, MS

Region 4 Desoto, located in Hernando, MS, delivers a wide array of addiction recovery services for both adults and young adults. This center features intensive outpatient care, outpatient programs, and standard outpatient treatment options, addressing substance use disorders alongside co-occurring mental health challenges. Employing evidence-based techniques like cognitive behavioral therapy, brief interventions, and contingency management, the facility customizes its treatment strategies to meet the unique needs of each client. Additionally, special programs cater specifically to active military members, adult men, and adult women. Prioritizing high-quality support, Region 4 Desoto fosters a nurturing environment for healing and recovery for clients of all genders facing issues related to substance use and mental health.

Region 8 Mental Health Services

Region 8 Mental Health Services located in Brookhaven, MS, provides outpatient support for individuals dealing with substance use and concurrent disorders for both adults and children. With expertise in 12-step programs, anger management, and brief intervention techniques, this center caters to the unique needs of active military personnel, teenagers, and adult males. Welcoming individuals of all ages and genders, the facility emphasizes high-quality care aimed at facilitating recovery. Featuring a variety of specialized programs and a comprehensive treatment approach, Region 8 Mental Health Services is committed to assisting individuals in attaining enduring sobriety and mental health.

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Region 2 Mental Health Center, situated in Tutwiler, MS, is dedicated to providing comprehensive care for individuals struggling with addiction and co-occurring mental health conditions. They offer extended residential stays and round-the-clock support for both adults and young people. Their therapeutic methods include 12-step programs, emotional regulation training, and short-term counseling. Special attention is given to distinct services for teenagers, as well as those who have experienced intimate partner abuse, domestic violence, or sexual assault, offering them targeted assistance. This center is committed to delivering high-standard, personalized treatment plans to foster sustained wellness for all clients, encompassing men, women, and children.

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Region 8 Mental Health Services, located in Brandon, MS, offers an extensive selection of therapeutic programs designed to meet diverse requirements. This center focuses on detoxification, treatment for substance use disorders, and specialized assistance for individuals dealing with both substance use and severe mental health issues in adults, along with serious emotional challenges in children. The facility provides various treatment options, including intensive outpatient, outpatient, and day treatment programs, employing evidence-based techniques such as 12-step facilitation, anger management, and brief interventions. Additionally, Region 8 Mental Health Services features specialized initiatives for active military members, teenagers, and adult males. Catering to adults and seniors of all genders, this center prioritizes high-quality care customized to meet the distinct needs of each individual.

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Region 8 Mental Health Services, located in Hazlehurst, MS, specializes in providing extensive addiction treatment options specifically for adult women facing issues related to substance use and co-occurring mental health disorders. The center offers a variety of programs, including long-term residential stays, outpatient services, and standard outpatient treatments, emphasizing strategies such as 12-step facilitation, anger management, and brief intervention techniques. Additionally, it features distinctive programs designed for active military personnel, adult women, and those impacted by intimate partner violence. Serving adults, seniors, and young adults, Region 8 Mental Health Services places a strong emphasis on addressing the unique needs of female clients. The facility is committed to delivering exceptional care and personalized support for individuals on their journey to recovery from addiction.

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Region 8 Mental Health Services, located in Mendenhall, MS, provides extensive long-term and short-term residential care for adult men grappling with addiction and severe mental health conditions that occur alongside it. The facility prioritizes a trauma-informed approach, incorporating methods like 12-step facilitation, anger management techniques, and brief intervention strategies. Their treatment plans are designed for adults, seniors, and young adults, with each client receiving personalized care. Emphasizing support for individuals with dual diagnoses of mental health and substance use disorders, this center delivers excellent care within a nurturing setting. For specialized treatment of addiction and mental health issues, Region 8 Mental Health Services is a valuable resource.

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Region I Mental Health Center, located in Tunica, MS, provides extensive outpatient services for individuals coping with substance abuse and related mental health issues, serving both adults and children. The available programs feature outpatient day services, standard outpatient meetings, and utilize scientifically supported methods including 12-step guidance, short interventions, and cognitive behavioral therapy. This center also has targeted programs for active military personnel, teens, and adult males, accommodating a wide demographic. It offers high-quality care for both adult men and women, ensuring that treatment is customized to meet the unique requirements of each person.

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Region III Chem Dependency, located in Tupelo, MS, provides a wide range of addiction recovery services for both adults and adolescents facing challenges related to substance misuse. The center specializes in addressing the needs of clients with dual diagnosis, offering long-term residential care, outpatient services, and medication-assisted treatment options. Emphasizing the principles of 12-step programs, anger management, and cognitive behavioral strategies, Region III Chem Dependency adopts a comprehensive approach to rehabilitation. This facility is particularly noteworthy for its customized programs designed for those dealing with both mental health and substance use issues, accommodating individuals of all genders. Discover compassionate care and guidance in a supportive setting at this esteemed treatment center.

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In Iuka, MS, Region IV MH/MR stands as a trusted facility for individuals needing support in overcoming addiction. They provide outpatient care for substance use disorders, as well as tailored services for those with co-occurring mental health conditions, addressing the needs of adults and children with emotional challenges. The center employs a variety of therapeutic techniques, including 12-step facilitation, anger management, and brief interventions, serving a diverse clientele that spans adults, seniors, active military personnel, teenagers, and adult men. Region IV MH/MR is dedicated to offering high-quality, personalized treatment within a welcoming setting, aiding both male and female clients in their journey toward recovery.

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Corinth, MS

Region IV MHS located in Corinth, MS, provides outpatient services that focus on treating substance abuse and concurrent mental health challenges. Designed for both adults and young adults, this center employs regular outpatient practices grounded in evidence-based methods such as Cognitive Behavioral Therapy and Motivational Interviewing. Emphasizing a 12-step approach, the facility addresses the needs of clients with dual diagnoses. Region IV MHS is distinguished by its specific programs tailored for men and women, guaranteeing personalized and thorough care for every individual. Clients can anticipate receiving high-quality treatment and assistance in a friendly and supportive atmosphere at this center.

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Corinth, MS

Region IV MHS in Corinth, MS, provides outpatient services for adults battling substance use disorders alongside co-occurring mental health challenges. Their offerings are designed for adults and seniors, incorporating methods such as 12-step support, emotional regulation skills, and short-term therapeutic strategies. They also feature distinct programs for young people, adult men, and adult women, delivering personalized support to address a wide array of individual circumstances. The center prioritizes high standards and proven therapeutic techniques, guaranteeing thorough assistance for those on the path to recovery. Regardless of gender, individuals will find a nurturing atmosphere at Region IV MHS, fostering both healing and personal development.

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Region Ten Community Services Board in Charlottesville, VA, is dedicated to providing comprehensive, research-backed therapeutic services for individuals grappling with substance use and co-occurring mental health challenges, serving both younger and adult populations. Their offerings include structured intensive outpatient programs, general outpatient services, and a day treatment model, emphasizing techniques such as 12-step facilitation, anger management strategies, and concise intervention approaches. The facility distinguishes itself with specialized support for active military personnel, teenagers, and adult males, ensuring a wide spectrum of demographic needs are met. Their care extends to seniors and adults of all gender identities. Clients can anticipate a personalized, high-quality treatment experience within a nurturing and expert setting.

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Region XIV Singing River Services, located in Pascagoula, MS, provides an extensive array of addiction recovery programs. This center features both residential and short-term options aimed at adults and young adults, serving clients of all genders. Emphasizing 12-step methodologies, brief intervention strategies, and cognitive behavioral therapy, the facility customizes its approach to effectively handle co-existing mental health and substance use disorders. Additionally, specialized programs are offered for active military members, as well as tailored support for men and women. Region XIV Singing River Services is committed to delivering exceptional care within a nurturing environment to assist individuals in their recovery journey.

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Region XV Warren Yazoo Chem Dep Ctr, located in Vicksburg, MS, provides detox and treatment for substance use through a variety of programs, including intensive outpatient, long-term residential, and standard outpatient care. The center employs methods such as 12-step strategies, brief interventions, and cognitive behavioral therapy to assist both adult men and women, including those dealing with concurrent mental health and substance use challenges. Catering to adults and young adults from all backgrounds, the facility offers customized care designed to meet the unique needs of each individual. Committed to delivering high-quality, comprehensive services, Region XV Warren Yazoo Chem Dep Ctr is focused on guiding individuals on their recovery journey.

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Merrillville, IN

Regional Health Systems in Merrillville, IN, provides extensive rehabilitation for adults and older adults. Their expertise lies in treating addiction and concurrent mental health issues through intensive and standard outpatient care, including detox. They utilize methods like 12-step facilitation, anger management, and brief intervention to address individual needs. Specific programs are available for expectant and new mothers, as well as those facing dual diagnoses. Serving all genders, this center prioritizes well-rounded recovery and effective treatment for individuals struggling with addiction.

Frequently Asked Questions

How are bipolar disorder and substance use connected?
Bipolar disorder and substance use disorders co-occur at high rates, with about 40-60% of people with bipolar disorder also experiencing addiction. During manic episodes, increased impulsivity and risk-taking can lead to substance use. During depressive episodes, people may self-medicate. Substances also destabilize mood, trigger episodes, and interfere with medication effectiveness, making integrated treatment crucial.
What is the treatment approach for bipolar disorder and addiction?
Treatment combines mood stabilization, addiction recovery, therapy, and comprehensive support. This includes psychiatric medication management (mood stabilizers, atypical antipsychotics), substance use counseling, individual therapy, group therapy, family education, sleep regulation, stress management, and careful monitoring. Both conditions must be treated simultaneously by professionals experienced in dual diagnosis care.
Will mood stabilizers interact with addiction treatment?
No, mood stabilizers support recovery. Medications like lithium, valproate, lamotrigine, and atypical antipsychotics are essential for bipolar disorder management and don't interfere with addiction treatment. In fact, stabilizing mood makes recovery easier by reducing impulsivity, improving judgment, and decreasing self-medication urges. Never stop psychiatric medications without medical supervision.
Can substance use cause bipolar-like symptoms?
Yes, stimulant use can mimic mania, while withdrawal and depression can mimic bipolar depression. Accurate diagnosis requires assessment during a period of sobriety. This is why comprehensive dual diagnosis programs conduct thorough psychiatric evaluations, monitor symptoms over time, and involve psychiatrists experienced in differentiating substance-induced mood symptoms from bipolar disorder.
Is residential treatment recommended for bipolar disorder and addiction?
Residential treatment is often recommended, especially during mood episodes, after recent hospitalization, with severe addiction, or when outpatient treatment hasn't succeeded. The structured environment provides medication management, 24/7 monitoring, mood stabilization support, and intensive therapy. Some people do well with intensive outpatient care if they're stable, compliant with medication, and have good support systems.

About Bipolar Disorder Treatment

Bipolar disorder and substance use disorders co-occur at alarmingly high rates, with 40-60% of individuals with bipolar disorder also experiencing addiction. The combination creates unique challenges: mood episodes can trigger substance use, while substances destabilize mood and interfere with treatment. Integrated care addressing both conditions simultaneously is essential for stability and recovery.

Understanding Bipolar Disorder

Bipolar disorder involves extreme mood swings between manic/hypomanic episodes (elevated mood, increased energy, impulsivity, reduced need for sleep) and depressive episodes (low mood, lack of energy, hopelessness, difficulty functioning). These mood shifts significantly impact judgment, behavior, and vulnerability to substance use. During mania, increased impulsivity and risk-taking often lead to substance use, while depressive episodes may prompt self-medication attempts.

Why Treatment Must Be Integrated

Treating only one condition while ignoring the other typically fails. Substances destabilize mood, trigger episodes, reduce medication effectiveness, and worsen bipolar symptoms. Conversely, untreated bipolar disorder makes maintaining sobriety nearly impossible. Integrated programs with psychiatrists, addiction specialists, and therapists working together provide coordinated care recognizing the complex interaction between these conditions.

Medication Management

Mood stabilization is foundational to recovery. Medications include:

  • Mood Stabilizers: Lithium, valproate, lamotrigine regulate mood swings
  • Atypical Antipsychotics: Quetiapine, aripiprazole, olanzapine for mania and maintenance
  • Antidepressants: Sometimes used cautiously with mood stabilizers for bipolar depression

These medications are not addictive and do not interfere with addiction recovery—they support it by stabilizing mood, improving judgment, reducing impulsivity, and decreasing self-medication urges.

Comprehensive Treatment Components

Quality dual diagnosis programs provide:

  • Psychiatric Services: Regular medication management and monitoring
  • Individual Therapy: Addresses both conditions and underlying issues
  • Group Therapy: Peer support from others with co-occurring disorders
  • Family Education: Helping loved ones understand both conditions
  • Sleep Regulation: Critical for mood stability and recovery
  • Stress Management: Preventing triggers for both mood episodes and substance use
  • Relapse Prevention: For both bipolar episodes and addiction

Level of Care Considerations

Residential treatment is often recommended for bipolar disorder and addiction, especially during mood episodes, after hospitalization, with severe addiction, or when outpatient treatment hasn't succeeded. The structured environment provides medication management, 24/7 monitoring, intensive therapy, and support for both mood stabilization and addiction recovery.

Resources for bipolar disorder and addiction:

Find Bipolar Disorder by State

Browse bipolar disorder programs in states with the most treatment options.

Medically Reviewed Updated May 2026

Reviewed by licensed addiction specialists. Information reflects current clinical guidance.

Sources:SAMHSA·NIDA·CDC

Need immediate help? Call SAMHSA: 1-800-662-4357 (24/7, free)