Polysubstance Abuse Treatment Programs
Polysubstance abuse — using two or more drugs simultaneously or in close succession — dramatically increases overdose risk and complicates recovery. Below you will find what polysubstance use disorder is, why cross addiction develops, which drug combinations are most dangerous, and how integrated treatment programs address multiple addictions.
Found 66 rehab centers specializing in polysubstance abuse across the United States.
Polysubstance Abuse: Key Facts
Classification
Co-occurring substance use pattern
Also known as
Polydrug use, multiple substance abuse, co-addiction
Common combinations
Alcohol + benzos, opioids + stimulants, alcohol + opioids
Main risks
Unpredictable interactions, amplified overdose risk, organ damage
Addiction potential
Very high (multiple dependencies)
Withdrawal complexity
High — requires coordinated medical management
DSM-5 diagnosis
Multiple substance use disorders diagnosed separately
Recommended treatment
Integrated, comprehensive dual/multi-substance program
What Is Polysubstance Abuse?
Polysubstance abuse refers to a pattern of using two or more psychoactive substances simultaneously or in close succession to enhance, modify, or counteract the effects of each drug. This is distinct from simply having tried different drugs at different points in life — polysubstance abuse involves intentional or habitual co-use of multiple substances during the same period. Common examples include drinking alcohol while taking benzodiazepines, combining opioids with stimulants, or mixing cocaine with alcohol.
Polysubstance abuse is extremely common among people with substance use disorders. Research published by the National Institute on Drug Abuse (NIDA) indicates that the majority of people who seek treatment for addiction report using more than one substance. The danger is compounded because the interactions between drugs are often unpredictable — each substance alters how the body metabolizes the other, creating risks that are far greater than the sum of using each substance alone.
It is important to note that the DSM-5 removed "polysubstance dependence" as a standalone diagnosis. Previously, a person could receive a single diagnosis covering their use of multiple substances. Under current diagnostic criteria, each substance use disorder is diagnosed separately. For example, a person who abuses both alcohol and opioids would receive two diagnoses: alcohol use disorder and opioid use disorder. This change was made to improve clinical precision but can sometimes obscure the interconnected nature of polydrug use in treatment planning.
Polysubstance use is more dangerous than single-substance use for several critical reasons. Drug interactions can amplify toxic effects on the heart, liver, and brain. The risk of fatal overdose increases exponentially when central nervous system (CNS) depressants are combined. And withdrawal from multiple substances simultaneously creates overlapping symptoms that are harder to manage medically and more likely to lead to dangerous complications.
Polysubstance Use Disorder: How It Is Diagnosed
Under the DSM-5, there is no single "polysubstance use disorder" diagnosis. Instead, clinicians evaluate each substance a person uses against the 11 criteria for substance use disorder, which include loss of control over use, continued use despite negative consequences, tolerance, withdrawal, cravings, and impairment in social or occupational functioning. A person meets the threshold for a substance use disorder when they exhibit at least two of these criteria within a 12-month period for a given substance. The severity is classified as mild (2-3 criteria), moderate (4-5 criteria), or severe (6 or more criteria).
Diagnosing polysubstance use disorder presents unique clinical challenges. Patients may not fully disclose all substances they are using, either due to stigma, fear of legal consequences, or because they do not consider certain substances (like alcohol or marijuana) to be part of their problem. The effects of one substance can mask or mimic the effects of another, making it difficult to determine which symptoms belong to which drug. Comprehensive toxicology screening and honest clinical interviews are essential for accurate assessment.
Many treatment centers now use integrated screening protocols specifically designed to capture polysubstance use patterns. Tools like the Addiction Severity Index (ASI) and the ASSIST (Alcohol, Smoking and Substance Involvement Screening Test) evaluate use across multiple substance categories. These instruments help clinicians develop a complete picture of a person's substance use and create a treatment plan that addresses all active addictions rather than focusing on a single "primary" substance.
Cross Addiction: When One Substance Leads to Another
Cross addiction is the phenomenon where a person recovering from dependence on one substance develops a new dependence on a different substance. This happens because addiction fundamentally changes the brain's reward circuitry — the neural pathways that were hijacked by the first substance remain vulnerable to hijacking by another. A person who has developed addiction to one substance has a significantly elevated risk of developing addiction to any other psychoactive substance, even one that seems unrelated to their original drug of choice.
Cross addiction is remarkably common and often begins innocuously. A person recovering from alcohol use disorder may be prescribed benzodiazepines for anxiety and develop a new dependence. Someone in recovery from opioid addiction may start drinking heavily, reasoning that alcohol was never "their problem." A person who has quit cocaine may begin using prescription stimulants. In each case, the person's brain — already primed for addiction — rapidly develops a compulsive relationship with the new substance.
Understanding cross addiction is critical for treatment planning. Effective recovery programs educate patients about this vulnerability and develop strategies to address it. This includes careful management of prescribed medications (especially those with abuse potential), development of non-chemical coping strategies for pain, anxiety, and insomnia, and ongoing monitoring for early signs of transfer to a new substance. People in recovery should discuss the risk of cross addiction openly with their treatment providers and be transparent about any new substance use.
Common and Dangerous Drug Combinations
Certain drug combinations are particularly lethal because of how they interact in the body. Understanding these interactions is essential because many people who engage in polysubstance abuse are unaware of just how dangerous specific combinations are.
Alcohol and Benzodiazepines
Both alcohol and benzodiazepines (Xanax, Valium, Klonopin, Ativan) are central nervous system depressants that enhance the activity of GABA, the brain's primary inhibitory neurotransmitter. When combined, their sedative effects do not simply add together — they multiply. This synergistic CNS depression can rapidly slow breathing to dangerous levels, cause loss of consciousness, and lead to respiratory failure and death. Emergency departments frequently see fatal overdoses involving this combination, and withdrawal from concurrent alcohol and benzodiazepine dependence is among the most medically dangerous withdrawal syndromes, requiring careful inpatient management.
Opioids and Stimulants
The combination of opioids with stimulants — known as a speedball (heroin + cocaine) or goofball (methamphetamine + heroin) — is one of the most dangerous patterns of polydrug use. Users combine these substances believing that the stimulant will counteract the sedative effects of the opioid, allowing them to use more of both. In reality, the stimulant masks the warning signs of opioid overdose (extreme drowsiness, slowed breathing) while placing enormous stress on the cardiovascular system. When the stimulant wears off — often before the opioid — respiratory depression can set in suddenly and fatally. This combination has been implicated in numerous high-profile overdose deaths.
Alcohol and Opioids
Alcohol and opioids are both CNS depressants, and their combined use dramatically increases the risk of fatal respiratory depression. Alcohol impairs judgment and reduces inhibition, making it more likely that a person will take a higher dose of opioids than intended. The combination also compounds liver toxicity — acetaminophen-containing opioid formulations (like Vicodin or Percocet) combined with alcohol can cause acute liver failure. The CDC reports that alcohol is involved in a significant percentage of opioid overdose deaths, making this one of the most common lethal combinations in the United States.
Cocaine and Alcohol
When cocaine and alcohol are used together, the liver produces a unique metabolite called cocaethylene. Cocaethylene has a longer half-life than cocaine, prolonging the euphoric effects — which is why many users combine these substances. However, cocaethylene is significantly more cardiotoxic than either substance alone. It increases the risk of sudden cardiac death by up to 18 times compared to cocaine use alone. Cocaethylene also intensifies the toxic effects on the liver and amplifies impulsive and aggressive behavior. This combination is one of the most common patterns of polysubstance abuse treated in emergency departments.
Benzodiazepines and Opioids
The combination of benzodiazepines and opioids is the single most common drug combination found in overdose deaths in the United States. Both drug classes depress the central nervous system and suppress breathing. The FDA has issued its strongest warning (a Black Box Warning) about the dangers of combining these medications. Despite this, co-prescribing remains common, and many people who obtain opioids illicitly also use benzodiazepines. Fentanyl — now the leading cause of overdose death — is frequently found mixed with counterfeit benzodiazepine pills, meaning users may unknowingly be taking this lethal combination.
Why Polysubstance Abuse Is More Dangerous
Using multiple substances simultaneously creates risks that extend far beyond the dangers of any single drug. The body's ability to metabolize and eliminate toxins is finite — when multiple substances compete for the same metabolic pathways in the liver, blood levels of each drug can rise to dangerous levels. A dose of one substance that would be survivable on its own can become lethal when combined with another substance that competes for the same liver enzymes.
One of the most insidious dangers of polysubstance abuse is that one drug can mask the warning signs of overdose from another. Stimulants can keep a person conscious and alert even as opioids suppress their breathing to dangerous levels. Alcohol can make a person feel less intoxicated by cocaine, leading them to use more of both. This masking effect means people who use multiple substances are more likely to unknowingly cross the threshold into overdose.
The organ damage from polysubstance abuse is compounded. The liver, which must process every substance a person ingests, faces dramatically increased workload. The heart is stressed by competing signals — stimulants accelerate heart rate while depressants slow it, creating dangerous arrhythmias. The brain is subjected to conflicting neurochemical signals that accelerate neurological damage. Chronic polysubstance abuse leads to faster deterioration of physical and mental health compared to single-substance use.
Withdrawal from multiple substances is significantly more complex and dangerous than single-substance withdrawal. Different substances have different withdrawal timelines, and symptoms can overlap and compound each other. For example, a person withdrawing from both alcohol and benzodiazepines simultaneously faces a heightened risk of seizures that is greater than withdrawing from either substance alone. Medical teams must carefully coordinate detoxification protocols when multiple dependencies are present, which is why supervised medical detox is essential for polysubstance users.
Signs of Polysubstance Abuse
Signs someone is using multiple substances
- Rapid and unpredictable mood swings
- Alternating between hyperactivity and extreme sedation
- Paraphernalia for multiple drug types (pipes, needles, pill bottles, rolling papers)
- Unexplained financial problems or missing money
- Physical symptoms that don't match a single substance (e.g., dilated and constricted pupils at different times)
- Frequent visits to multiple doctors or pharmacies
Signs of polysubstance dependence
- Inability to function without using multiple substances
- Using one substance to counteract or manage effects of another
- Withdrawal symptoms that vary in nature and intensity
- Multiple failed attempts to quit one substance while continuing others
- Severe health decline across multiple organ systems
- History of emergency room visits for overdose or adverse reactions
Treatment for Polysubstance Abuse
Why treatment is more complex
Treating polysubstance abuse is significantly more complex than treating single-substance addiction. Each substance creates its own pattern of physical dependence, withdrawal risk, and psychological craving. Treatment providers must address all active addictions simultaneously — treating only the "primary" substance while ignoring others almost always leads to relapse. Integrated treatment that addresses all substances, along with any co-occurring mental health conditions, produces the best outcomes.
Medical detoxification
Medical detoxification is particularly important for polysubstance users because withdrawal from certain combinations (especially alcohol plus benzodiazepines, or multiple CNS depressants) can be life-threatening. Medical teams must carefully sequence and coordinate the detox process. In some cases, substances are tapered sequentially — stabilizing the patient on one substance before withdrawing another. In other cases, simultaneous medically managed withdrawal is appropriate. The approach depends on which substances are involved, the severity of each dependence, and the patient's overall health.
Medication-Assisted Treatment (MAT)
Medication-Assisted Treatment plays an important role in polysubstance recovery. For opioid dependence, medications like buprenorphine (Suboxone) or naltrexone (Vivitrol) can stabilize cravings. For alcohol dependence, naltrexone, acamprosate, or disulfiram may be appropriate. When a person has both opioid and alcohol use disorders, naltrexone can address both simultaneously. MAT decisions in polysubstance cases require careful coordination to avoid interactions between treatment medications and to ensure all active dependencies are being addressed.
Behavioral therapies
Cognitive Behavioral Therapy (CBT) is the cornerstone of polysubstance abuse treatment. CBT helps patients identify the triggers, situations, and thought patterns that lead to use of each substance. Because polysubstance users often have complex trigger patterns — where the use of one substance triggers cravings for another — therapy must address these interconnected patterns rather than treating each substance in isolation. Contingency management, motivational interviewing, and group therapy all play supporting roles in comprehensive treatment.
Treating co-occurring mental health conditions
Polysubstance abuse is strongly associated with co-occurring mental health conditions including depression, anxiety disorders, PTSD, ADHD, and personality disorders. Dual diagnosis treatment that addresses both addiction and mental health simultaneously is essential. Many people who use multiple substances are self-medicating — using stimulants for ADHD or depression, opioids for physical or emotional pain, and benzodiazepines or alcohol for anxiety. Without addressing the underlying condition, the person will continue to seek chemical solutions to their distress.
Need Help Finding the Right Treatment Center?
Speak with a compassionate specialist now - 100% free & confidential
Find Polysubstance Abuse Treatment Centers Near You
Use the search bar and filters below to find treatment centers that specialize in multi-substance addiction. Look for programs offering integrated detox protocols, comprehensive psychiatric assessment, medication-assisted treatment, and experience treating patients with multiple concurrent substance use disorders.
Showing 20 of 66 results
Situated in Mesa, AZ, the Adolescent Substance Abuse Program delivers targeted treatment for young individuals dealing with substance use issues within an outpatient framework. It incorporates proven methods like cognitive behavioral therapy, motivational interviewing, and strategies for preventing relapse, ensuring a personalized approach that meets the distinct requirements of its young female clientele. Supporting a diverse range of ages, including adults, children, seniors, and young adults, the intensive outpatient program at this center provides essential assistance for those looking to conquer their substance use challenges. Emphasizing high-quality care and specialized attention for adolescents, the facility serves as a crucial ally for both individuals and families on the journey to recovery.
The Adolescent Substance Abuse Program, located in Glendale, AZ, delivers comprehensive outpatient and intensive outpatient services for individuals struggling with addiction. This center employs proven therapeutic modalities, including cognitive behavioral therapy, motivational interviewing, and strategies for sustained sobriety. Their expertise lies in offering specialized, high-quality care designed with adolescents in mind, though they also serve adults, seniors, and young adults. The program is particularly focused on providing support to females. By integrating scientifically validated methods, the center is dedicated to empowering individuals to conquer addiction and cultivate lasting well-being. For those in need of expert-driven adolescent addiction treatment in a nurturing setting, this program offers a promising avenue for healing.
Area Substance Abuse Council in Cedar Rapids, IA, provides outpatient addiction recovery services for adults and older individuals. Their approach emphasizes customized treatment, incorporating 12-step support, brief counseling, and cognitive behavioral techniques. Serving both men and women, the center fosters a nurturing atmosphere. Their dedication to tailored treatment strategies and proven therapeutic methods distinguishes them as a premier option for comprehensive substance use disorder care.
Situated in Cedar Rapids, IA, the Area Substance Abuse Council provides an extensive variety of services for substance use treatment. This center features options for transitional housing and halfway houses, designed for those who are looking for a nurturing environment during their recovery process. It focuses on addressing co-occurring substance use disorders as well as significant mental health challenges in adults and emotional issues in children. The facility offers multiple treatment formats, including intensive outpatient, outpatient, and standard outpatient services. It employs various methodologies, such as 12-step programs, anger management techniques, and brief therapeutic interventions. Additionally, specialized programs are available for active military members, as well as for adult men and women, ensuring that individuals of all ages and genders receive the high-quality care they need on their path to recovery.
The Area Substance Abuse Council, located in Cedar Rapids, IA, specializes in providing treatment for adults facing substance use disorders along with co-existing mental health challenges, as well as supporting children dealing with emotional issues. Their wide-ranging programs encompass intensive outpatient care, outpatient services, and day treatment alternatives. The center utilizes proven methodologies, including 12-step programs, anger management, and brief therapeutic interventions. It also features specific programs designed for active military personnel, teenagers, and adult males, ensuring that it meets the needs of various demographics. Those in search of dedicated care and personalized assistance for substance use concerns will discover a supportive and effective treatment setting at this center.
The Area Substance Abuse Council, situated in Cedar Rapids, IA, provides an extensive array of rehabilitation services. This center focuses on treating substance use disorders, offering transitional living options as well as support for individuals facing both substance use issues and serious mental health conditions. With a variety of treatment formats, including long-term, short-term, and residential programs, the center delivers personalized care through techniques like 12-step facilitation, anger management, and brief interventions. Additionally, specialized programs are available for active military personnel, adult men, and adult women. Catering to adults, seniors, and young adults of all genders, this facility is committed to delivering top-notch support for those striving to overcome substance abuse and mental health obstacles.
Situated in Phoenix, AZ, the Adolescent Substance Abuse Program stands out as a premier center dedicated to addressing substance use issues. This establishment provides both intensive outpatient and traditional outpatient services specifically designed for younger individuals. Utilizing research-backed methods like cognitive behavioral therapy, motivational interviewing, and strategies for preventing relapse, the program prioritizes female participants while also serving adults, seniors, and young adults. The center's tailored approach and dedication to excellence make it a top option for individuals in search of thorough and effective substance abuse treatment.
The Area Substance Abuse Council, situated in Cedar Rapids, Iowa, specializes in outpatient substance use therapy for adults and seniors. Employing methods like 12-step facilitation, brief intervention, and cognitive behavioral therapy, this center delivers customized support aligned with individual requirements. The program adopts a personalized strategy, serving both male and female individuals. Its core mission is to provide excellent care and assistance to those aiming for recovery from substance dependency. For those seeking effective treatment with a bespoke approach, this institution could be a fitting option for their path to wellness.
Nestled in Warren, AR, the 10th District Substance Abuse Program delivers extensive support for individuals battling substance use. Their offerings include structured intensive outpatient services, day treatment, and partial hospitalization. Employing strategies like 12-step integration, anger management, and brief intervention, the center accommodates adult men and women, even those facing dual diagnoses of mental health and substance use challenges. The program also provides supportive housing and sober living environments for adults and young adults. With dedicated tracks for male and female participants, this center is committed to delivering exceptional care and personalized recovery pathways.
Situated in Hackensack, New Jersey, the Adolescent Substance Abuse Program provides accessible outpatient support for those facing challenges with drug or alcohol dependence. This center is equipped to serve adolescents, adults, and young adults, irrespective of gender identity. Employing therapeutic strategies including 12-step integration, emotional regulation techniques, and concise counseling, the program is designed to cater to the specific requirements of every person. Committed to high standards of care and tailored recovery paths, this facility is devoted to guiding individuals toward sustained wellness. For anyone in need of thorough addiction treatment within a nurturing setting, the Adolescent Substance Abuse Program is a valuable resource.
Situated in Maquoketa, IA, the Area Substance Abuse Council delivers extensive substance use rehabilitation for both adults and children dealing with concurrent mental health challenges. The center offers a range of services including intensive outpatient care, day programs, and partial hospitalization. It employs various strategies such as 12-step methodologies, anger management techniques, and short-term interventions. The facility serves active military members, teens, adult males, and people of all genders. Committed to providing high-quality support, this center aims to assist adults and seniors in their journey to recovery and enhanced mental health.
The Area Substance Abuse Council, situated in Vinton, IA, delivers thorough substance use disorder recovery services for individuals of all ages, including those concurrently experiencing significant mental health challenges. Their treatment modalities encompass intensive outpatient, day treatment, and standard outpatient care. The facility features specialized therapeutic interventions like 12-step support, anger management techniques, and brief counseling. Distinctive programs tailored for active-duty military personnel, adult men, and women distinguish this center. Catering to adults and older adults irrespective of gender, the Area Substance Abuse Council is committed to delivering high-quality, scientifically supported care to aid individuals in their journey toward lasting sobriety.
Situated in Cedar Rapids, IA, the Area Substance Abuse Council serves as a multifaceted rehabilitation facility that offers a range of programs including long-term, short-term, and 24-hour residential care. This center focuses on treating substance use disorders, providing transitional housing solutions, and addressing co-occurring mental health issues. It is designed to meet the needs of adult women who are coping with substance-related and psychological difficulties. The center also implements specialized programs for military personnel, survivors of intimate partner violence, and individuals requiring anger management support, creating a nurturing environment for healing. Utilizing methodologies like 12-step facilitation and brief intervention strategies, the facility emphasizes high-quality care tailored for adults of all ages seeking individualized treatment options.
The Area Substance Abuse Council, situated in Clinton, IA, delivers a full spectrum of care for individuals struggling with substance use, fostering a nurturing atmosphere. This establishment features extended, brief, and round-the-clock inpatient options designed for adult women and older adults. Employing methods like motivational encouragement and therapy for substance use disorders, the center excels in aiding patients who have co-occurring mental health conditions and past trauma. Offering housing support during the recovery process, this center champions a complete path to wellness. For those in search of expert assistance in a setting tailored for women, the Area Substance Abuse Council in Clinton is committed to delivering excellent treatment and ongoing encouragement.
The Area Substance Abuse Council, located in Anamosa, IA, delivers extensive treatment for adults dealing with substance use issues alongside mental health disorders. The center features various programs, including intensive outpatient, outpatient, and day treatment, employing evidence-based techniques such as 12-step facilitation and anger management training. It has specialized offerings for active duty military personnel, adolescents, and adult males, addressing a wide range of community needs. Customized services are provided for both men and women, as well as seniors. With an emphasis on personalized care and a multidisciplinary strategy, the center aims to provide effective support to individuals on their journey to recovery from substance use and mental health challenges.
Situated in Clinton, IA, the Area Substance Abuse Council provides a wide range of treatment options for substance use issues. This center specializes in intensive outpatient programs, standard outpatient services, and partial hospitalization/day treatment. Incorporating methods such as motivational incentives and contingency management, alongside counseling for substance use disorders, the facility accommodates adolescents, men, and women. Dedicated to serving adults and seniors of diverse backgrounds, the center prioritizes personalized treatment for each client. With an emphasis on high-quality care, the Area Substance Abuse Council is a reputable option for individuals looking for effective rehabilitation in the Clinton region.
The Area Substance Abuse Council located in Manchester, IA, offers a broad range of services for individuals struggling with substance use, specifically catering to adults and seniors. The center's offerings include intensive outpatient programs as well as more standard outpatient options. Utilizing evidence-based methods such as 12-step programs, brief interventions, and cognitive behavioral therapy, the facility creates personalized treatment strategies that address the unique circumstances of each individual. Additionally, specialized programs are available to support teenagers, adult men, and adult women, ensuring targeted and effective treatment. With an emphasis on gender-sensitive care, this center strives to provide high-quality support to assist clients in achieving long-term recovery. For those in search of dependable addiction recovery assistance within a nurturing setting, this facility presents a variety of services to facilitate the path to sobriety.
Situated in Manchester, IA, the Area Substance Abuse Council delivers focused treatment options for adults facing substance use issues, including those who also have significant mental health conditions or emotional challenges in children. The center offers multiple treatment modalities, such as intensive outpatient, outpatient, and partial hospitalization programs. Utilizing customized methods including 12-step facilitation, anger management, and brief interventions, this facility aims to provide personalized care. Special programs are available for active duty military members, adolescents, and adult men. The center is committed to offering quality support and care for individuals of all ages and genders seeking to overcome substance abuse challenges.
The Area Substance Abuse Council in Dubuque, IA, provides an array of programs designed to treat substance use issues for individuals with varying needs. This center features several treatment options, including intensive outpatient services, outpatient care, and regular outpatient programs. Employing methods like 12-step facilitation, anger management, and brief interventions, the facility customizes treatment strategies to fit the specific needs of each client. It also offers specialized programs for adolescents, as well as adult men and women, ensuring support for different age groups and genders. Whether for personal recovery or assistance for a loved one, clients can count on receiving high-quality care and effective support throughout their recovery journey at this center.
Situated in Clinton, IA, the Area Substance Abuse Council provides outpatient treatment options for substance use aimed at adults and older individuals. This center incorporates methods such as 12-step facilitation, brief interventions, and cognitive behavioral therapy, delivering a well-rounded recovery experience. Prioritizing personalized care, the facility serves both men and women, ensuring that treatment plans are specifically designed to meet the unique needs of each person. For anyone in search of effective addiction treatment in a nurturing atmosphere, the Area Substance Abuse Council stands out as a commendable option for embarking on a path to recovery.
Browse polysubstance abuse programs in states with the most treatment options:
Treatment Approaches
Levels of Care
How To Choose the Right Treatment Center for Polysubstance Abuse
Experience with multiple SUDs
Look for programs that routinely treat patients with two or more concurrent substance use disorders — not just a primary substance with secondary issues.
Integrated detox protocols
The center should offer medically supervised detoxification that can safely manage withdrawal from multiple substances simultaneously or sequentially.
Psychiatric support on staff
Polysubstance abuse frequently co-occurs with mental health conditions. Choose a center with psychiatrists who can assess and treat co-occurring disorders.
MAT availability for multiple substances
Ensure the program can provide medication-assisted treatment for all applicable dependencies — opioid, alcohol, and others — coordinated together.
Verify insurance coverage
Multi-substance treatment may require longer stays. Ask the center to verify your benefits and confirm coverage for the anticipated length of treatment.
Check credentials and outcomes
Look for CARF or Joint Commission accreditation. Ask about their experience with polysubstance cases and what their completion and relapse rates look like.
Related Treatment Approaches and Levels of Care
Frequently Asked Questions About Polysubstance Abuse
Medical Review and Sources
Trusted Resources
Substance Abuse and Mental Health Services Administration
Federal agency providing information, resources, and treatment locator for substance abuse and mental health.
Helpline: 1-800-662-4357
National Institute on Drug Abuse
NIH institute advancing science on drug use and addiction causes, consequences, and treatment.
National Institute on Alcohol Abuse and Alcoholism
NIH institute supporting research on alcohol's impact on health and providing treatment resources.
Need Help Finding Treatment Now?
Polysubstance abuse requires specialized care. Speak with a compassionate specialist who can help you find a treatment program equipped to handle multiple substance dependencies — 100% free and confidential, available 24/7.