Naltrexone and Vivitrol Treatment Centers
Naltrexone is an FDA-approved opioid antagonist medication used to treat both alcohol dependence and opioid use disorder. Available as a daily oral tablet (Revia) or a monthly Vivitrol injection, naltrexone works by blocking opioid receptors in the brain to reduce cravings and prevent relapse. Use our directory to find treatment centers that offer naltrexone-based medication-assisted treatment near you.
Found 7,994 treatment centers offering naltrexone (vivitrol) across the United States.
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2nd Chance Treatment Center, located in Gilbert, AZ, provides a wide range of outpatient services aimed at helping individuals recover from substance use disorders alongside mental health issues. The center emphasizes techniques such as brief intervention, cognitive behavioral therapy, and motivational interviewing. Programs are specifically designed for various groups, including active duty service members, adolescents, and adult males. Personalized treatment strategies are crafted for adults, children or adolescents, and young adults, with programs tailored for different genders. The center offers services like detoxification, outpatient treatment for substance use, and medications such as methadone, buprenorphine, or naltrexone. Discover compassionate and effective support at 2nd Chance Treatment Center.

2nd Chance Treatment Center in Phoenix, AZ, provides extensive outpatient care for those pursuing freedom from addiction and related mental health challenges. The center features tailored programs for current military members, teenagers, and adult men, welcoming adults and young adults of any gender. Employing proven techniques such as cognitive behavioral therapy and motivational interviewing, the center is committed to delivering superior support customized for each person's unique journey. Offering services from detox to ongoing outpatient care and medication-assisted treatment (methadone, buprenorphine, or naltrexone), 2nd Chance Treatment Center is devoted to guiding clients toward enduring recovery and overall well-being.

Situated in Mission Viejo, California, 449 Recovery is dedicated to providing tailored substance abuse treatment for adults facing significant mental health challenges or emotional issues in children. This center features intensive outpatient programs, day treatment services, and partial hospitalization options. Emphasizing approaches such as 12-step support, anger management, and brief interventions, it serves both men and women, including clients who have undergone intimate partner or domestic violence. With a commitment to delivering personalized care, this facility offers a supportive atmosphere for adults and adolescents pursuing holistic rehabilitation solutions.

6390 Meadows Court LLC, situated in Malibu, California, specializes in extensive detox and treatment services for substance use issues. This center features residential detox programs, round-the-clock care, and short-term residential options for adult men and women, including those who have faced traumatic experiences. Emphasizing cognitive behavioral therapy, strategies for relapse prevention, and counseling for substance use disorders, the facility serves both adults and young adults. With tailored services available for male and female participants, 6390 Meadows Court LLC is committed to delivering exceptional care and support for those in need of effective rehabilitation in a peaceful environment.

7th Street, situated in Salt Lake City, UT, provides expert rehabilitation for individuals of all ages facing substance abuse and concurrent mental health challenges. Their offerings include intensive outpatient, extended residential stays, and standard outpatient care, incorporating methods like 12-step support, emotional regulation training, and concise counseling. Customized treatment plans are developed for adult men, adult women, and those with histories of trauma. Catering to adults and young adults of both genders, the center delivers high-standard care and extensive support.

A Beautiful Mind Inc in Chicago, IL, delivers extensive addiction care for individuals of all ages facing co-occurring severe mental health conditions or emotional challenges. Their programs include intensive outpatient, outpatient, and standard outpatient care, incorporating methods like 12-step facilitation, anger management, and brief interventions. The facility offers tailored services for teens, adult men, and adult women, accommodating a wide range of clients. Serving adults and young adults across all genders, A Beautiful Mind Inc prioritizes individualized, quality treatment, establishing itself as a leading provider of successful recovery solutions.

4C Health, located in Rochester, IN, specializes in outpatient treatment for substance abuse and offers targeted support for individuals facing both substance use disorders and significant mental health complications. The facility employs a range of evidence-based methods, including anger management, brief intervention, and cognitive behavioral therapy, as part of its regular outpatient services. With programs specifically designed for adolescents, women, and survivors of intimate partner violence, 4C Health addresses the needs of various client groups. The center provides effective treatment for adults and seniors of all genders, focusing on personalized care and extensive support for those striving to overcome addiction and mental health issues.

1 Method in Los Angeles, CA offers residential detoxification and short-term and long-term residential substance use treatment, with programs for veterans and active duty military. Buprenorphine and naltrexone are used in treatment. TRICARE, private insurance, self-pay, and a sliding fee scale are accepted.

1 Method Center in Los Angeles, California provides residential detoxification plus short-term and long-term residential substance use treatment for young adults, adults, and seniors, with programs for veterans and active duty military. Buprenorphine and naltrexone are used in treatment. Payment options include TRICARE, private insurance, and a sliding fee scale.

12 South Recovery in Lake Forest, CA delivers outpatient day treatment, intensive outpatient, and medication-based care with buprenorphine and naltrexone. Programs serve veterans, military families, pregnant women, forensic clients, and people with HIV or trauma histories. TRICARE, tribal funds, private insurance, and state-financed plans are accepted.

Operating as Hillside Wellness Center in Levittown, PA, this facility offers short-term and long-term residential substance use treatment for adults with co-occurring serious mental illness. Programming covers pregnant and postpartum women, trauma survivors, and domestic violence survivors, with buprenorphine and naltrexone available. Payment is through private insurance or self-pay.

Outpatient addiction treatment with buprenorphine or naltrexone, including an intensive outpatient track, is provided by 2nd Chance in Lexington, Kentucky. The program treats young adults, adults, and seniors. Medicare, Medicaid, private insurance, and self-payment are accepted forms of payment.

2nd Chance Treatment Center in Litchfield Park, AZ, provides extensive outpatient care for those pursuing freedom from addiction. Their expertise includes detox, addiction treatment, and addressing co-occurring mental health issues in adults, alongside emotional challenges in younger individuals. Employing techniques like motivational interviewing, relapse prevention, and counseling for substance use disorders, they craft personalized recovery paths. With dedicated programs for active military, teens, and adult men, 2nd Chance Treatment Center serves a wide spectrum of clients. They welcome adults and youth of all genders, committed to delivering excellent support and care throughout the sobriety process.

Outpatient detoxification and treatment with buprenorphine and naltrexone are provided by 406 Recovery in Bozeman, Montana, including care for adults with co-occurring serious mental illness. Programs serve adult women and men and clients with trauma histories. Medicare, Medicaid, TRICARE, and federal government funding are accepted.

Located in Peru, IN, 4C Health specializes in outpatient care for substance use disorders, as well as support for individuals facing both substance use and significant mental health challenges in adults, along with emotional issues in children. The center offers treatments involving methadone, buprenorphine, or naltrexone, applying modalities such as cognitive behavioral therapy, anger management, and brief intervention strategies. There are dedicated programs designed specifically for adolescents, adult males, and females. With a commitment to serving adults and older adults of diverse backgrounds, 4C Health prioritizes individualized treatment approaches and evidence-based methods, highlighting its dedication to providing exceptional care for patients on their recovery journey.

Operating within Primary Care Spa Wellness in Springdale, Arkansas, this center offers outpatient substance use treatment using buprenorphine and naltrexone, with programs for adolescents, pregnant and postpartum women, veterans, and criminal justice clients. Clients with co-occurring mental health or pain disorders are also served. Medicare, SAMHSA block grants, and state-financed plans are accepted.

820 River Street Inc, situated in Queensbury, NY, specializes in extensive treatment for adults dealing with substance use issues alongside serious mental health challenges, as well as providing support for children with emotional difficulties. The center offers various treatment options, including intensive outpatient, outpatient services, and methadone/buprenorphine programs. They employ techniques such as 12-step support, brief interventions, and cognitive behavioral therapy. With tailored programs for active duty military personnel, teenagers, and adult males, this facility serves a wide array of clients. Committed to providing personalized, top-notch care for both adults and children/adolescents of all genders, 820 River Street Inc is focused on aiding clients in achieving successful rehabilitation outcomes.

Methadone, buprenorphine, and naltrexone support outpatient detox and opioid treatment at this Milwaukee, WI, clinic operated by Milwaukee Health Services System LLC. A program for pregnant and postpartum women is offered alongside care for co-occurring disorders. Medicare, Medicaid, and state-financed plans are accepted, with Spanish-language services.

A Bridge Back Inc, situated in Arlington Heights, IL, delivers an extensive array of rehabilitation services designed for those facing challenges with substance use disorders along with associated mental health issues. The center features options like intensive outpatient care, outpatient day programs, and partial hospitalization, employing proven methods such as cognitive behavioral therapy, anger management techniques, and brief interventions. Tailored programs are designed specifically for active military members, as well as for adult men and women. Prioritizing high-quality care, this facility supports both adults and young adults of all backgrounds, creating a nurturing and organized atmosphere to facilitate recovery and assist individuals in reintegrating into everyday life.

Operating as Trost Health New Jersey, this Freehold, New Jersey center provides intensive and regular outpatient substance use treatment with naltrexone used in care. It treats adults with co-occurring mental health disorders and serves young adults, women, men, and older adults. Private health insurance is accepted.

820 River Street Inc, located in Albany, NY, delivers a wide range of substance use recovery programs that include intensive outpatient care, outpatient services, as well as methadone, buprenorphine, and naltrexone therapies. Emphasizing methods such as 12-step support, anger management, and brief intervention techniques, this center serves adult men and women, along with clients who have a history of trauma. They offer specialized treatment options for both adults and children/adolescents, ensuring a comprehensive approach for male and female clients alike. Recognized for its exceptional care and customized treatment plans, 820 River Street Inc stands as an essential option for individuals seeking effective rehabilitation solutions in the Albany region.
Frequently Asked Questions
What is naltrexone and how does it work?
What are the most common naltrexone side effects?
What is Vivitrol and how is the injection administered?
What is the difference between naltrexone and naloxone?
How does naltrexone compare to Suboxone?
What is the standard naltrexone dosage?
How much does naltrexone cost and does insurance cover it?
What is low dose naltrexone (LDN)?
About Naltrexone (Vivitrol)
Naltrexone is an opioid antagonist, meaning it binds to the mu-opioid receptors in the brain without activating them. By occupying these receptors, naltrexone effectively blocks the rewarding effects of opioids and reduces the neurochemical reinforcement that drives alcohol cravings. Unlike medications such as methadone or buprenorphine, naltrexone has no potential for abuse or physical dependence because it produces no opioid effect whatsoever.
How Naltrexone Works
When a person taking naltrexone consumes alcohol, the pleasurable dopamine surge that normally reinforces drinking behavior is significantly blunted. For individuals with opioid dependence, naltrexone prevents any ingested opioid from reaching the receptors, rendering opioid use ineffective. This pharmacological mechanism makes naltrexone a cornerstone of medication-assisted treatment (MAT) programs across the country. Naltrexone was first approved by the FDA in 1984 for opioid dependence and received additional approval for alcohol dependence in 1994.
Naltrexone Side Effects
Common side effects include:
- Nausea, especially during the first few days
- Headache and dizziness
- Fatigue and insomnia
- Joint and muscle pain
- Decreased appetite and anxiety
Serious side effects are less common but include signs of liver injury such as yellowing of the skin or eyes, dark urine, and persistent abdominal pain. Severe injection site reactions from Vivitrol, including tissue necrosis, have been reported in rare cases. Importantly, naltrexone lowers opioid tolerance over time — if a person discontinues naltrexone and attempts to use opioids at previously tolerated doses, the risk of fatal overdose increases significantly.
Naltrexone for Alcohol Dependence
Naltrexone is one of only three FDA-approved medications for alcohol use disorder, alongside disulfiram (Antabuse) and acamprosate (Campral). For individuals struggling with alcohol dependence, naltrexone reduces heavy drinking days and increases the percentage of days abstinent. The oral formulation, sold under the brand name Revia, is typically prescribed at 50 mg daily and is most effective when combined with behavioral therapy and support groups.
Naltrexone for Opioid Dependence
For opioid dependence, naltrexone serves as a relapse-prevention tool rather than a detox medication. Patients must complete a full opioid detoxification and remain opioid-free for a minimum of 7 to 14 days before beginning naltrexone therapy. Starting naltrexone while opioids are still present can trigger sudden and severe precipitated withdrawal. Once initiated, naltrexone provides a pharmacological safety net — if a patient relapses, naltrexone blocks the drug from producing its usual effects.
Vivitrol: Injectable Naltrexone
Vivitrol is the brand name for naltrexone extended-release injectable suspension, delivering 380 mg in a single intramuscular dose once per month. A healthcare provider injects Vivitrol into the gluteal muscle using a special needle included in the product kit, alternating sides each month. The Vivitrol shot has become increasingly popular because it solves one of the biggest challenges in addiction treatment: medication adherence. Studies show that patients receiving monthly Vivitrol injections are significantly more likely to remain in treatment compared to those prescribed daily oral naltrexone.
Vivitrol Side Effects
Vivitrol shares many side effects with oral naltrexone but carries additional risks related to the injection site. These range from mild tenderness, redness, and swelling to severe complications including induration and in rare cases tissue necrosis requiring surgical intervention. As with oral naltrexone, Vivitrol can affect liver function, and depressed mood and suicidal thoughts have also been reported.
Revia: Oral Naltrexone Brand
Revia is the primary brand name for oral naltrexone hydrochloride tablets in a 50 mg strength. Today, most prescriptions are filled with generic naltrexone, which is bioequivalent and significantly less expensive. The main advantage of oral naltrexone over injectable Vivitrol is lower cost and greater dosing flexibility, but it requires daily compliance, which patients in early recovery frequently struggle with.
Low Dose Naltrexone (LDN)
Low dose naltrexone (LDN) refers to naltrexone prescribed at doses ranging from 0.5 mg to 5 mg — a fraction of the standard 50 mg addiction treatment dose. LDN is used off-label and is not FDA-approved for any condition at these low doses. It is not a treatment for addiction and operates through a fundamentally different mechanism. The theory proposes that a brief, transient blockade of opioid receptors causes a rebound effect that increases the body's natural endorphin production. LDN has been investigated for conditions including fibromyalgia, multiple sclerosis, and Crohn's disease, but large-scale clinical trials are still needed.
Naltrexone Cost and Insurance
Generic oral naltrexone typically costs $30 to $80 per month without insurance. With insurance or discount programs, out-of-pocket cost can fall below $15. Vivitrol injections cost $1,000 to $1,800 without insurance, but most private plans, Medicaid, and Medicare cover it. Alkermes offers the Vivitrol Co-Pay Savings Program for insured patients and a Patient Assistance Program for those without insurance.
Naltrexone Dosage
The standard oral dose is 50 mg once daily, with some providers starting at 25 mg for the first day to minimize side effects. For Vivitrol, the dose is 380 mg as a single intramuscular injection every four weeks. Patients must be opioid-free for a minimum of 7 to 14 days before initiating either formulation.
Naltrexone vs Naloxone: What's the Difference?
Both are opioid antagonists, but they differ in duration and use. Naloxone (Narcan) is a short-acting emergency overdose reversal agent that takes effect within minutes and wears off in 30 to 90 minutes. Naltrexone is a long-acting antagonist for ongoing relapse prevention, providing blockade for 24 hours (oral) or 30 days (Vivitrol). Naloxone is also a component of Suboxone, where it deters injection misuse.
Naltrexone vs Suboxone
Suboxone contains buprenorphine (a partial opioid agonist) that mildly stimulates opioid receptors, reducing cravings and withdrawal. Naltrexone fully blocks receptors with zero agonist activity. Patients must be fully detoxed before starting naltrexone, whereas Suboxone can be initiated during early withdrawal. A landmark 2017 clinical trial (X:BOT) found that among patients who successfully started treatment, relapse rates were similar between Vivitrol and Suboxone.
Naltrexone and Weight Loss
Naltrexone is one of two active ingredients in Contrave (naltrexone/bupropion), an FDA-approved weight management medication. However, naltrexone alone is not approved for weight loss. Some patients undergoing addiction treatment report modest weight changes related to reduced alcohol calories or appetite-suppressing side effects, but naltrexone should not be selected as an addiction medication primarily for weight effects.
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