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Medically Reviewed Content
Updated: October 2026
Sources: SAMHSA, NIDA

Naltrexone and Vivitrol Treatment Centers

Naltrexone is an FDA-approved opioid antagonist medication used to treat both alcohol dependence and opioid use disorder. Available as a daily oral tablet (Revia) or a monthly Vivitrol injection, naltrexone works by blocking opioid receptors in the brain to reduce cravings and prevent relapse. Use our directory to find treatment centers that offer naltrexone-based medication-assisted treatment near you.

Found 6,655 treatment centers offering naltrexone (vivitrol) across the United States.

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Abbey LLC
Bettendorf, IA

Situated in Bettendorf, IA, Abbey LLC delivers a wide range of addiction recovery services for both adults and young adults. The facility focuses on detoxification, treatment for substance use disorders, and offers tailored care for those with simultaneous mental health concerns. To ensure that clients receive personalized support, Abbey LLC provides various treatment modalities, including intensive outpatient, long-term residential, and outpatient programs. The center employs evidence-based techniques, such as cognitive behavioral therapy and 12-step facilitation, as well as specialized programs designed for adult men, women, and individuals with dual diagnoses. With an emphasis on high-quality care and customized treatment plans, Abbey LLC is committed to assisting clients throughout their recovery journey.

Able to Change Recovery Inc
San Juan Capistrano, CA

Able to Change Recovery Inc, situated in San Juan Capistrano, CA, delivers targeted substance abuse rehabilitation for adults and adolescents. Their services include intensive outpatient programs, standard outpatient care, and day treatment or partial hospitalization options. The center emphasizes 12-step facilitation, anger management techniques, and brief intervention strategies, specifically addressing the needs of those with co-occurring mental health challenges. Able to Change Recovery Inc serves both men and women, fostering a welcoming and inclusive atmosphere. This institution is committed to providing high-quality, individualized care to support enduring recovery and overall well-being.

Absolute Awakenings Treatment Center

Absolute Awakenings Treatment Center, situated in Denville, NJ, provides a holistic approach to treating substance use disorders and co-occurring serious mental health conditions in adults, as well as addressing serious emotional issues in children. Emphasizing intensive outpatient care, partial hospitalization, and outpatient day programs, the center delivers customized treatment plans that incorporate methods such as 12-step facilitation, cognitive behavioral therapy, and brief interventions. The center features specialized programs designed for adult men, women, and those with trauma histories. Catering to individuals of all genders, Absolute Awakenings Treatment Center prioritizes personalized care through evidence-based practices and tailored strategies.

Acadia Hospital
Bangor, ME

Acadia Hospital, located in Bangor, ME, specializes in rehabilitation services aimed at addressing substance abuse and concurrent mental health disorders. The facility offers both intensive outpatient and standard outpatient programs designed for adults facing significant emotional challenges or mental health conditions. Treatment options encompass techniques such as anger management, cognitive behavioral therapy, and the Matrix Model. They also feature tailored programs for adult men, women, and those who have faced trauma. Focusing on the needs of adults and young adults, Acadia Hospital provides gender-specific treatment for both sexes. The center is dedicated to delivering high-quality care and creating individualized treatment strategies to assist individuals in their recovery journey.

Access Blue Island Family Health Ctr

Access Blue Island Family Health Ctr, located in Blue Island, IL, specializes in outpatient care for adults and adolescents struggling with substance misuse and co-occurring severe mental health conditions. The facility offers distinct programs designed for adult men, adult women, and individuals diagnosed with HIV or AIDS, emphasizing personalized treatment pathways. Their therapeutic methods encompass brief counseling, substance use disorder therapy, and outpatient medication-assisted treatment involving methadone, buprenorphine, or naltrexone. This center is dedicated to providing high-quality, supportive services to both male and female patients seeking comprehensive recovery solutions in a supportive setting.

Access Booker Family Health Ctr

Access Booker Family Health Center, located in Chicago, IL, provides tailored outpatient treatment for adults facing substance use challenges, especially those dealing with concurrent severe mental health conditions or emotional issues in children. The center boasts specialized programs designed for both adult males and females, as well as clients living with HIV or AIDS. Various treatment methods are utilized, including brief intervention, cognitive behavioral therapy, and the Matrix Model. Catering to adults and young adults of any gender, the center also offers outpatient methadone/buprenorphine and naltrexone therapies alongside standard outpatient services. Access Booker Family Health Center is dedicated to delivering high-quality care and support to individuals pursuing comprehensive rehabilitation in the Chicago region.

ARS of Ephrata
Ephrata, PA

Situated in Ephrata, Pennsylvania, ARS of Ephrata delivers extensive treatment for substance use through outpatient services and medication-assisted options such as methadone, buprenorphine, or naltrexone. The center focuses on remedies for anger management, provides brief interventions, and employs cognitive behavioral therapy. It offers distinct programs designed for those affected by trauma, members of the LGBTQ community, as well as expectant and new mothers. Catering to adults and young adults of all identities, ARS of Ephrata ensures high-quality support in a nurturing atmosphere. If you or someone you care about is in need of substance use assistance featuring specialized programs and proven methodologies, this center is well-prepared to aid in the recovery process.

Abilene Betty Hardwick

Abilene Betty Hardwick, located in Abilene, TX, delivers a full spectrum of recovery support for adults and older adults. They feature intensive outpatient, general outpatient, and outpatient detox options. This center excels in addressing addiction and co-occurring psychological challenges, employing proven methods like cognitive behavioral therapy, motivational interviewing, and techniques to prevent relapse. Prioritizing personalized attention, Abilene Betty Hardwick crafts treatment paths suited to each individual's specific circumstances. Both men and women are served with distinguished, gender-attuned care at this esteemed recovery establishment.

Access Austin Family Health Ctr

Access Austin Family Health Center, located in Chicago, IL, provides an extensive range of outpatient services for individuals battling substance use issues and concurrent mental health conditions, applicable to both adults and children. The facility offers focused support for adults experiencing significant emotional challenges. By employing evidence-backed methods such as cognitive behavioral therapy and motivational incentives, Access Austin Family Health Center delivers customized treatment strategies for men and women, including those living with HIV/AIDS. The center also offers outpatient options for methadone, buprenorphine, and naltrexone, accommodating adult and young adult clients of all genders. Prioritizing high-quality care and personalized assistance, Access Austin Family Health Center is committed to helping clients navigate their journey to recovery from substance use disorders.

Absolute Control Transitional

Situated in Burbank, CA, Absolute Control Transitional specializes in a wide array of addiction recovery services. The center offers detoxification, treatment for substance use disorders, and transitional housing with a variety of options including intensive outpatient, long-term residential, and outpatient programs. It employs targeted strategies such as 12-step facilitation, anger management, and brief intervention, catering to adult men and women, including those affected by intimate partner violence. Absolute Control Transitional is dedicated to providing exceptional care to adults and young adults of all genders, guiding them through their recovery process.

ASCEND Csl and Recovery Services

ASCEND Csl and Recovery Services located in Portsmouth, OH, provides comprehensive treatment for individuals dealing with substance abuse and concurrent mental health issues, catering to both adults and children. The center offers a variety of services including intensive outpatient programs, outpatient care, and day treatment, employing tailored strategies such as 12-step facilitation, anger management, and cognitive behavioral therapy. Distinct programs are available for adult men, adult women, and those who have faced trauma. This facility is dedicated to serving individuals of all genders, including seniors, and emphasizes personalized care to facilitate clients' journeys toward recovery.

Access Behavioral Health Services

Access Behavioral Health Services in Nampa, ID, delivers targeted interventions for addiction and simultaneous mental health conditions. They offer robust intensive outpatient and standard outpatient programs, along with medication-assisted treatments like methadone, buprenorphine, or naltrexone. Employing techniques such as anger management, cognitive behavioral therapy, and the Matrix Model, the center customizes care to each person's unique situation. Specific programs are designed for young people, adult males, and adult females. Serving a broad age range from children to adults and accommodating all genders, Access Behavioral Health Services provides complete support for individuals navigating recovery from substance abuse and mental health struggles.

Access Behavioral Health Services

Access Behavioral Health Services in Boise, ID, delivers extensive substance abuse recovery options for individuals of all ages. Their offerings encompass intensive outpatient services, standard outpatient care, and targeted treatments utilizing methadone, buprenorphine, or naltrexone. The center employs scientifically validated therapeutic methods including anger management, cognitive behavioral therapy, and the Matrix Model. Designed to accommodate the unique requirements of adolescents, adult men, and adult women, the facility provides specialized pathways to recovery. This center, serving both genders, is dedicated to providing superior support for those addressing substance use disorders and co-occurring mental health challenges.

ARTS Potomac Street Center

Nestled in Aurora, Colorado, the ARTS Potomac Street Center delivers complete care for individuals struggling with substance use disorders, serving both adults and younger adults. Their offerings include intensive outpatient, standard outpatient, and medication-assisted treatment options using methadone, buprenorphine, or naltrexone. Addressing key areas such as anger management, brief interventions, and cognitive behavioral therapy, the center is equipped to support adult men and women, as well as those who have faced trauma. Tailored programs are a hallmark, ensuring each person receives personalized support. The ARTS Potomac Street Center is committed to high standards and proven methods, guiding individuals toward lasting recovery.

Access Brandon Family Health Ctr

Brandon Family Health Center, located in Chicago, IL, provides outpatient treatment for substance use disorders in adults who are facing serious mental health challenges, along with emotional issues in children. This center offers outpatient options for methadone, buprenorphine, or naltrexone, combined with ongoing outpatient services. Emphasizing brief interventions, cognitive behavioral therapy, and the Matrix Model, clients benefit from personalized treatment plans. There are dedicated programs available for adult men and women, along with specialized services for individuals living with HIV or AIDS. This facility supports adults and young adults across all genders, focusing on high-quality, evidence-based care to assist each individual in their recovery journey.

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Orchard Park, NY

Situated in Orchard Park, NY, Abbott stands out as a leading rehab facility that specializes in outpatient care for substance use disorders and co-occurring issues in both adults and children. The center offers various treatment options, which include outpatient therapy utilizing methadone, buprenorphine, or naltrexone. Emphasizing evidence-based methods such as cognitive behavioral therapy and anger management, Abbott serves active-duty military members, teenagers, and adult males. By providing tailored care for both men and women, Abbott is dedicated to helping individuals navigate their recovery from addiction and mental health difficulties.

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Lafayette, LA

Acadiana CARES, located in Lafayette, Louisiana, delivers a wide array of services focused on substance use rehabilitation. It includes transitional housing and specialized treatment for adults grappling with both substance use issues and significant mental health disorders, as well as support for children facing emotional challenges. The center offers several treatment modalities, such as intensive outpatient programs, long-term residential options, and general outpatient services, employing techniques like 12-step support, anger management, and cognitive behavioral therapy. Designed to meet the distinct needs of adult men, adult women, and clients affected by HIV or AIDS, Acadiana CARES ensures that care is both high-quality and highly personalized, tailoring treatment plans to foster effective recovery for individuals across all genders.

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Acadiana Recovery Center, situated in Lafayette, LA, delivers comprehensive substance use disorder treatment for adults and young adults. Services include inpatient hospital care around the clock and intensive outpatient programs. The center utilizes methodologies like 12-step facilitation, anger management, and brief intervention, serving both male and female individuals, including survivors of intimate partner violence. Tailored treatment is available for adult men and women, ensuring individualized support. Acadiana Recovery Center stands as a dedicated provider of extensive addiction recovery services.

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Access Ashland Family Health Ctr offers expert care for substance abuse recovery.

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ATS of Cecil County Inc in Baltimore, MD, provides tailored substance abuse recovery services for adults and young adults. Their offerings include outpatient care, as well as specialized programs utilizing methadone/buprenorphine or naltrexone, alongside standard outpatient services. Emphasizing personalized support, the center incorporates methods such as 12-step facilitation, anger management, and brief intervention to combat addiction. ATS of Cecil County Inc serves a diverse clientele, welcoming both men and women into a nurturing setting. For those in search of thorough addiction treatment that prioritizes individual needs, this center is committed to delivering excellent care to support each person's path to wellness.

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Situated in Rochester, NY, AYA (Adolescent/Young Adult) serves as a dedicated rehabilitation facility providing outpatient care for adults and young adults battling substance misuse. This establishment focuses on addressing dual diagnoses of substance use disorders and significant mental health challenges, fostering a caring and encouraging atmosphere. The therapeutic modalities employed encompass anger management, brief intervention strategies, and cognitive behavioral therapy. AYA distinguishes itself with tailored programs specifically designed for adolescents, young adults, and individuals managing both mental health and substance use issues concurrently. Committed to delivering high-quality support for those on their journey to wellness, the center offers individualized treatment plans catering to the needs of both male and female participants.

Frequently Asked Questions

What is naltrexone and how does it work?
Naltrexone is an opioid antagonist medication approved by the FDA to treat both alcohol use disorder and opioid dependence. It works by binding to opioid receptors in the brain, blocking the euphoric and sedative effects of opioids and reducing alcohol cravings. Naltrexone is available as an oral tablet (brand name Revia) and as a monthly injection (brand name Vivitrol).
What are the most common naltrexone side effects?
The most common naltrexone side effects include nausea, headache, dizziness, fatigue, insomnia, and anxiety. Some patients also experience joint or muscle pain, decreased appetite, and stomach cramps. Most side effects are mild and tend to diminish within the first few weeks of treatment. Serious but rare side effects include liver damage, so physicians typically monitor liver function during treatment.
What is Vivitrol and how is the injection administered?
Vivitrol is the brand name for extended-release naltrexone, delivered as a once-monthly intramuscular injection. The Vivitrol injection is administered by a healthcare provider into the gluteal muscle and slowly releases naltrexone over approximately 30 days. This eliminates the need for daily pill compliance, making it a preferred option for many patients in recovery from alcohol or opioid dependence.
What is the difference between naltrexone and naloxone?
Although their names sound similar, naltrexone and naloxone serve different purposes. Naloxone (brand name Narcan) is a short-acting opioid antagonist used as an emergency rescue medication to reverse opioid overdoses, while naltrexone is a long-acting antagonist taken on a scheduled basis to prevent relapse. Naloxone works within minutes but wears off quickly, whereas naltrexone provides sustained receptor blockade over hours or weeks depending on the formulation.
How does naltrexone compare to Suboxone?
Naltrexone and Suboxone take fundamentally different approaches to treating opioid dependence. Suboxone contains buprenorphine (a partial opioid agonist) and reduces withdrawal symptoms by mildly activating opioid receptors, while naltrexone fully blocks those receptors without any opioid effect. Patients must be fully detoxed from opioids before starting naltrexone, whereas Suboxone can be initiated during early withdrawal. The best choice depends on individual treatment history and clinical needs.
What is the standard naltrexone dosage?
The standard oral naltrexone dosage for both alcohol and opioid dependence is 50 mg taken once daily. Some providers use an initial dose of 25 mg for the first day to minimize side effects. For Vivitrol, the dosage is 380 mg delivered as a single intramuscular injection once every four weeks. Dosage should not be adjusted without medical supervision.
How much does naltrexone cost and does insurance cover it?
Generic oral naltrexone tablets typically range from $30 to $80 per month without insurance. Vivitrol injections are considerably more expensive, often costing $1,000 to $1,800 per injection without coverage. Most private insurance plans, Medicaid, and Medicare cover naltrexone in both forms, and manufacturer assistance programs are available for eligible patients.
What is low dose naltrexone (LDN)?
Low dose naltrexone (LDN) refers to naltrexone taken at very small doses, typically between 1 mg and 5 mg, far below the standard 50 mg addiction treatment dose. LDN is used off-label for conditions such as chronic pain, fibromyalgia, and certain autoimmune disorders, and it is not an approved treatment for addiction. Patients should not confuse LDN with standard naltrexone therapy for substance use disorders.

About Naltrexone (Vivitrol)

Naltrexone is an opioid antagonist, meaning it binds to the mu-opioid receptors in the brain without activating them. By occupying these receptors, naltrexone effectively blocks the rewarding effects of opioids and reduces the neurochemical reinforcement that drives alcohol cravings. Unlike medications such as methadone or buprenorphine, naltrexone has no potential for abuse or physical dependence because it produces no opioid effect whatsoever.

How Naltrexone Works

When a person taking naltrexone consumes alcohol, the pleasurable dopamine surge that normally reinforces drinking behavior is significantly blunted. For individuals with opioid dependence, naltrexone prevents any ingested opioid from reaching the receptors, rendering opioid use ineffective. This pharmacological mechanism makes naltrexone a cornerstone of medication-assisted treatment (MAT) programs across the country. Naltrexone was first approved by the FDA in 1984 for opioid dependence and received additional approval for alcohol dependence in 1994.

Naltrexone Side Effects

Common side effects include:

  • Nausea, especially during the first few days
  • Headache and dizziness
  • Fatigue and insomnia
  • Joint and muscle pain
  • Decreased appetite and anxiety

Serious side effects are less common but include signs of liver injury such as yellowing of the skin or eyes, dark urine, and persistent abdominal pain. Severe injection site reactions from Vivitrol, including tissue necrosis, have been reported in rare cases. Importantly, naltrexone lowers opioid tolerance over time — if a person discontinues naltrexone and attempts to use opioids at previously tolerated doses, the risk of fatal overdose increases significantly.

Naltrexone for Alcohol Dependence

Naltrexone is one of only three FDA-approved medications for alcohol use disorder, alongside disulfiram (Antabuse) and acamprosate (Campral). For individuals struggling with alcohol dependence, naltrexone reduces heavy drinking days and increases the percentage of days abstinent. The oral formulation, sold under the brand name Revia, is typically prescribed at 50 mg daily and is most effective when combined with behavioral therapy and support groups.

Naltrexone for Opioid Dependence

For opioid dependence, naltrexone serves as a relapse-prevention tool rather than a detox medication. Patients must complete a full opioid detoxification and remain opioid-free for a minimum of 7 to 14 days before beginning naltrexone therapy. Starting naltrexone while opioids are still present can trigger sudden and severe precipitated withdrawal. Once initiated, naltrexone provides a pharmacological safety net — if a patient relapses, naltrexone blocks the drug from producing its usual effects.

Vivitrol: Injectable Naltrexone

Vivitrol is the brand name for naltrexone extended-release injectable suspension, delivering 380 mg in a single intramuscular dose once per month. A healthcare provider injects Vivitrol into the gluteal muscle using a special needle included in the product kit, alternating sides each month. The Vivitrol shot has become increasingly popular because it solves one of the biggest challenges in addiction treatment: medication adherence. Studies show that patients receiving monthly Vivitrol injections are significantly more likely to remain in treatment compared to those prescribed daily oral naltrexone.

Vivitrol Side Effects

Vivitrol shares many side effects with oral naltrexone but carries additional risks related to the injection site. These range from mild tenderness, redness, and swelling to severe complications including induration and in rare cases tissue necrosis requiring surgical intervention. As with oral naltrexone, Vivitrol can affect liver function, and depressed mood and suicidal thoughts have also been reported.

Revia: Oral Naltrexone Brand

Revia is the primary brand name for oral naltrexone hydrochloride tablets in a 50 mg strength. Today, most prescriptions are filled with generic naltrexone, which is bioequivalent and significantly less expensive. The main advantage of oral naltrexone over injectable Vivitrol is lower cost and greater dosing flexibility, but it requires daily compliance, which patients in early recovery frequently struggle with.

Low Dose Naltrexone (LDN)

Low dose naltrexone (LDN) refers to naltrexone prescribed at doses ranging from 0.5 mg to 5 mg — a fraction of the standard 50 mg addiction treatment dose. LDN is used off-label and is not FDA-approved for any condition at these low doses. It is not a treatment for addiction and operates through a fundamentally different mechanism. The theory proposes that a brief, transient blockade of opioid receptors causes a rebound effect that increases the body's natural endorphin production. LDN has been investigated for conditions including fibromyalgia, multiple sclerosis, and Crohn's disease, but large-scale clinical trials are still needed.

Naltrexone Cost and Insurance

Generic oral naltrexone typically costs $30 to $80 per month without insurance. With insurance or discount programs, out-of-pocket cost can fall below $15. Vivitrol injections cost $1,000 to $1,800 without insurance, but most private plans, Medicaid, and Medicare cover it. Alkermes offers the Vivitrol Co-Pay Savings Program for insured patients and a Patient Assistance Program for those without insurance.

Naltrexone Dosage

The standard oral dose is 50 mg once daily, with some providers starting at 25 mg for the first day to minimize side effects. For Vivitrol, the dose is 380 mg as a single intramuscular injection every four weeks. Patients must be opioid-free for a minimum of 7 to 14 days before initiating either formulation.

Naltrexone vs Naloxone: What's the Difference?

Both are opioid antagonists, but they differ in duration and use. Naloxone (Narcan) is a short-acting emergency overdose reversal agent that takes effect within minutes and wears off in 30 to 90 minutes. Naltrexone is a long-acting antagonist for ongoing relapse prevention, providing blockade for 24 hours (oral) or 30 days (Vivitrol). Naloxone is also a component of Suboxone, where it deters injection misuse.

Naltrexone vs Suboxone

Suboxone contains buprenorphine (a partial opioid agonist) that mildly stimulates opioid receptors, reducing cravings and withdrawal. Naltrexone fully blocks receptors with zero agonist activity. Patients must be fully detoxed before starting naltrexone, whereas Suboxone can be initiated during early withdrawal. A landmark 2017 clinical trial (X:BOT) found that among patients who successfully started treatment, relapse rates were similar between Vivitrol and Suboxone.

Naltrexone and Weight Loss

Naltrexone is one of two active ingredients in Contrave (naltrexone/bupropion), an FDA-approved weight management medication. However, naltrexone alone is not approved for weight loss. Some patients undergoing addiction treatment report modest weight changes related to reduced alcohol calories or appetite-suppressing side effects, but naltrexone should not be selected as an addiction medication primarily for weight effects.

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Medically Reviewed Updated October 2026

Reviewed by licensed addiction specialists. Information reflects current clinical guidance.

Sources:SAMHSA·NIDA·CDC

Need immediate help? Call SAMHSA: 1-800-662-4357 (24/7, free)