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Medically Reviewed Content
Updated: May 2026
Sources: SAMHSA, NIDA

Naltrexone and Vivitrol Treatment Centers

Naltrexone is an FDA-approved opioid antagonist medication used to treat both alcohol dependence and opioid use disorder. Available as a daily oral tablet (Revia) or a monthly Vivitrol injection, naltrexone works by blocking opioid receptors in the brain to reduce cravings and prevent relapse. Use our directory to find treatment centers that offer naltrexone-based medication-assisted treatment near you.

Found 6,711 treatment centers offering naltrexone (vivitrol) across the United States.

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Acqua Recovery
Heber City, UT

Situated in Heber City, UT, Acqua Recovery delivers a wide array of research-backed treatment options for individuals grappling with substance use issues and related mental health challenges. The center offers intensive outpatient programs, outpatient day services, and partial hospitalization, employing various methodologies such as 12-step support, cognitive behavioral therapy, and strategies for anger management. Acqua Recovery is designed to serve different demographics, including active military members, adult males and females, as well as young adults. Prioritizing personalized care, this facility guarantees that clients receive tailored approaches that align with their distinct requirements. Whether individuals are in need of transitional housing, outpatient services, or sober living arrangements, Acqua Recovery fosters a nurturing atmosphere for sustainable recovery.

Acqua Recovery
Midway, UT

Situated in Midway, UT, Acqua Recovery provides a wide array of rehabilitation services aimed at adults and young adults who are on the path to recovery from substance use disorders. The center features detox programs, intensive outpatient care, and extended residential services, employing techniques like cognitive behavioral therapy and the 12-step program. Acqua Recovery has a particular focus on helping active duty military members, as well as adult men and women. Additionally, the facility offers transitional living arrangements and anger management assistance, ensuring personalized care for both genders and emphasizing the importance of maintaining long-term sobriety.

Acqua Recovery
Midway, UT

Nestled in Midway, UT, Acqua Recovery delivers extensive support for individuals battling addiction. This facility offers vital services including detoxification, comprehensive substance use care, and structured transitional and sober living arrangements for adult men and women. Patients can engage in treatment through flexible formats like intensive outpatient, extended residential stays, and standard outpatient programs, all designed to meet individual requirements. Acqua Recovery utilizes proven therapeutic methods such as 12-step integration, anger management techniques, and cognitive behavioral therapy. Specialized offerings are available for active military personnel, as well as adult men and women. Catering to both adults and young adults, Acqua Recovery is committed to providing high-quality, personalized treatment for sustainable recovery.

Active Recovery
Bossier City, LA

Situated in Bossier City, LA, Active Recovery specializes in intensive outpatient programs, outpatient services, and treatments involving methadone, buprenorphine, or naltrexone for substance abuse. The center employs techniques such as anger management, brief intervention, and cognitive behavioral therapy to create customized treatment plans for each client. Catering to adults and young adults of diverse backgrounds, Active Recovery is distinguished by its emphasis on individualized care. Its dedication to delivering high-quality and efficient treatment makes this facility a top option for individuals looking for focused addiction recovery support in a friendly and nurturing atmosphere.

ACTS Behavioral Health and

In Lakewood, WA, ACTS Behavioral Health provides comprehensive treatment programs for adults struggling with substance use and co-occurring mental health conditions, as well as for children with serious emotional disturbances. Their services encompass intensive outpatient, outpatient, and regular outpatient levels of care. Utilizing therapeutic approaches such as anger management, brief intervention, and cognitive behavioral therapy, ACTS Behavioral Health delivers tailored support. They offer personalized treatment plans for adults and children, accommodating both male and female clients who are looking for effective addiction recovery and mental health support in a nurturing setting.

Active Recovery
Shreveport, LA

Situated in Shreveport, LA, Active Recovery provides extensive substance abuse rehabilitation for both adults and adolescents. This center offers a range of services including intensive outpatient programs, outpatient care, and specialized options for methadone/buprenorphine or naltrexone treatment. Emphasizing strategies such as anger management, brief intervention, and cognitive behavioral therapy, Active Recovery customizes its programs to meet the unique needs of each client. Additionally, the facility features gender-specific treatment options for men and women, ensuring a high standard of individualized care to aid in achieving long-lasting recovery.

ACTS Behavioral Health and

Situated in Lynnwood, WA, ACTS Behavioral Health specializes in outpatient services for adults facing substance use challenges alongside significant mental health disorders, as well as for children experiencing serious emotional disturbances. Utilizing evidence-based methodologies such as anger management, brief intervention, and cognitive behavioral therapy, this center develops personalized programs for each individual. Catering to a diverse range of clients, including adults and children/adolescents of all genders, ACTS Behavioral Health is committed to delivering high-quality care through customized treatment plans. If you or someone you know is in need of thorough and effective addiction support, this program may be the ideal option for you.

Adams Behavioral Health

Located in Decatur, IN, Adams Behavioral Health provides outpatient services aimed at treating substance abuse and concurrent mental health issues in both adults and children. The center employs techniques like cognitive behavioral therapy, motivational interviewing, and anger management to deliver personalized treatment that meets diverse needs. It also features specialized programs designed for clients involved with the criminal justice system. Catering to adults and senior individuals regardless of gender, the facility emphasizes high-quality care grounded in evidence-based methods. Committed to a holistic approach to healing and recovery, Adams Behavioral Health stands as a reliable option for those in need of thorough and individualized rehabilitation assistance.

Adams Recovery Center

Adams Recovery Center, located in Loveland, OH, features a wide array of evidence-based services for addiction treatment. This facility focuses on detoxification and support for substance use disorders, offering a variety of programs including intensive outpatient care, long-term residential stays, and outpatient options for adults and young adults. With an emphasis on cognitive behavioral therapy, relapse prevention strategies, and counseling for substance use disorders, the center effectively serves both men and women. The personalized programs designed for different client demographics ensure that each individual receives dedicated care and assistance. Adams Recovery Center is recognized for its dedication to providing high-quality care and a holistic approach to recovery.

Adams Recovery Center
New Richmond, OH

Adams Recovery Center, situated in New Richmond, OH, delivers comprehensive, science-backed therapies for those battling addiction. Their services include medical detox, structured outpatient care, extended stay residential treatment, and flexible outpatient options. Employing proven methods like cognitive behavioral therapy, relapse management, and addiction counseling, the center serves adult men, adult women, and young adults. By offering distinct programs for various demographics, Adams Recovery Center prioritizes personalized healing for enduring sobriety. Clients can anticipate thorough assistance and expert care from dedicated specialists at this respected recovery facility.

Active Recovery
Minden, LA

Active Recovery in Minden, LA, provides specialized care for substance use disorders, offering intensive outpatient, outpatient, and medication-assisted treatment. The facility excels in anger management, brief intervention, and cognitive behavioral therapy. They have distinct programs designed for those impacted by intimate partner and domestic violence. Active Recovery supports adults and young adults across all genders, employing evidence-based practices for comprehensive recovery. Their dedication to high-quality, personalized treatment guides clients toward a life free from addiction.

Adanta Group
Monticello, KY

Situated in Monticello, KY, the Adanta Group delivers extensive outpatient services for adults dealing with substance use disorders alongside significant mental health challenges, as well as for children facing serious emotional difficulties. With expertise in areas such as anger management, cognitive behavioral therapy, and the Matrix Model, this center offers consistent outpatient treatment and medications like methadone, buprenorphine, or naltrexone. Tailored programs are available for pregnant and postpartum women, and the facility caters to adults and seniors across all genders. The Adanta Group is dedicated to providing high-quality care grounded in evidence-based practices to support individuals on their recovery journey.

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Situated in Rochester, NY, "Action for a Better Community" delivers extensive treatment options for substance use issues and specialized support for those facing severe mental health challenges alongside addiction. The center features diverse outpatient programs, including treatments involving methadone and buprenorphine. Emphasizing approaches such as 12-step facilitation, anger management, and brief interventions, the facility serves adult males and females, alongside children and teenagers who have encountered intimate partner violence. "Action for a Better Community" is dedicated to providing customized services for all genders, guaranteeing effective care for individuals pursuing recovery from substance use disorders and mental health difficulties.

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Centerville, UT

Situated in Centerville, UT, Active Recovery delivers a wide array of services aimed at assisting individuals in their journey toward overcoming addiction. This center focuses on treating substance use disorders, offering transitional housing and addressing the complexities of co-occurring substance use and significant mental health issues in adults, as well as serious emotional challenges in children. Active Recovery employs various treatment modalities, such as intensive outpatient care and day treatment programs. Their offerings include 12-step support, anger management techniques, and quick intervention strategies. The center is designed to meet the specific needs of active duty service members, as well as adult men and women, providing customized programs that cater to diverse requirements. Committed to delivering exceptional care, Active Recovery strives to help adults and young adults of all genders achieve sustainable recovery.

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The Acute Stabilization Unit in Providence, RI, offers dedicated substance use treatment and dual diagnosis support for individuals of all ages. Their residential and short-term residential options employ techniques like brief intervention, cognitive behavioral therapy, and relapse prevention. Specialized tracks are provided for adult men, women, and those with a history of trauma. The center also offers gender-specific programming for adults and young adults, encompassing both male and female clients. The Acute Stabilization Unit is committed to providing effective, personalized care aimed at fostering recovery and enhancing general health.

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Greensburg, KY

Adanta Group, located in Greensburg, KY, provides extensive outpatient services for both adults and children facing substance use issues, especially those with concurrent severe mental health challenges or emotional struggles. This center focuses on specific therapies, including anger management, cognitive behavioral therapy, and the Matrix Model, offering routine outpatient services alongside methadone/buprenorphine or naltrexone treatments. The programs are designed to support pregnant or postpartum women, as well as adults and seniors of all backgrounds. Emphasizing personalized treatment and proven methods, the center is dedicated to delivering top-notch care for individuals aiming to overcome addiction and mental health difficulties.

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Liberty, KY

The Adanta Group, situated in Liberty, KY, provides extensive outpatient services for individuals of all ages struggling with substance use disorders, including those with co-occurring mental health challenges. Employing proven therapeutic methods like cognitive behavioral therapy, anger management, and the Matrix Model, the center delivers individualized treatment plans. They uniquely support pregnant and postpartum women, demonstrating a dedication to diverse needs. Serving adult and senior men and women, the Adanta Group fosters a welcoming atmosphere. Clients can anticipate excellent care and customized support, whether they require standard outpatient services or specialized methadone/buprenorphine treatment.

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Campbellsville, KY

Adanta Group, located in Campbellsville, KY, specializes in outpatient treatment for adults dealing with substance use issues, particularly those with concurrent severe mental health conditions. They also extend their services to children experiencing significant emotional challenges. The center offers various treatment modalities, including outpatient programs involving methadone, buprenorphine, or naltrexone, alongside standard outpatient services to meet diverse patient requirements. By applying evidence-based methods such as cognitive behavioral therapy, anger management, and the Matrix Model, Adanta Group ensures an all-encompassing approach to treatment. Additionally, it features specialized programs for pregnant and postpartum women, distinguishing it from other facilities. The center serves adults and seniors of all gender identities, emphasizing personalized and high-quality rehabilitation care.

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Glasgow, KY

Adanta Group located in Glasgow, KY, specializes in outpatient care for adults and children facing substance abuse and concurrent mental health issues. The center employs various methodologies such as anger management, cognitive behavioral therapy, and the Matrix Model to customize treatment plans according to individual requirements. It also provides dedicated programs for pregnant or postpartum women, ensuring a wide range of support for different groups. Adanta Group serves adults and seniors of all genders and is committed to delivering high-quality, evidence-informed care to assist in the recovery process. Individuals in need of outpatient methadone or buprenorphine therapy, along with standard outpatient services, can receive tailored assistance at this center.

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Whitley City, KY

Situated in Whitley City, KY, the Adanta Group delivers targeted treatment for substance use issues alongside co-existing mental health challenges. This center provides outpatient care options, including treatments with methadone, buprenorphine, or naltrexone, customized for both adults and children. Utilizing evidence-based methodologies such as cognitive behavioral therapy, anger management, and the Matrix Model, the facility ensures thorough support. Importantly, the Adanta Group offers specific programs for women who are pregnant or in the postpartum phase and serves both male and female clients of all ages. Committed to high-quality and personalized treatment, this center stands as a vital resource for individuals on their recovery journey.

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Somerset, KY

Situated in Somerset, KY, the Adanta Group delivers targeted outpatient services for individuals battling substance abuse and concurrent severe mental health issues in adults, as well as significant emotional challenges in children. This center offers a range of treatment modalities, including outpatient methadone, buprenorphine, or naltrexone therapies, along with standard outpatient support. Emphasizing techniques such as anger management, cognitive behavioral therapy, and the Matrix Model, the facility customizes its services to meet each client's specific needs. Specialized programs for pregnant and postpartum women, together with resources available for adults and seniors across all genders, facilitate thorough and inclusive care. The Adanta Group is recognized for its exceptional treatment quality and varied therapeutic strategies.

Frequently Asked Questions

What is naltrexone and how does it work?
Naltrexone is an opioid antagonist medication approved by the FDA to treat both alcohol use disorder and opioid dependence. It works by binding to opioid receptors in the brain, blocking the euphoric and sedative effects of opioids and reducing alcohol cravings. Naltrexone is available as an oral tablet (brand name Revia) and as a monthly injection (brand name Vivitrol).
What are the most common naltrexone side effects?
The most common naltrexone side effects include nausea, headache, dizziness, fatigue, insomnia, and anxiety. Some patients also experience joint or muscle pain, decreased appetite, and stomach cramps. Most side effects are mild and tend to diminish within the first few weeks of treatment. Serious but rare side effects include liver damage, so physicians typically monitor liver function during treatment.
What is Vivitrol and how is the injection administered?
Vivitrol is the brand name for extended-release naltrexone, delivered as a once-monthly intramuscular injection. The Vivitrol injection is administered by a healthcare provider into the gluteal muscle and slowly releases naltrexone over approximately 30 days. This eliminates the need for daily pill compliance, making it a preferred option for many patients in recovery from alcohol or opioid dependence.
What is the difference between naltrexone and naloxone?
Although their names sound similar, naltrexone and naloxone serve different purposes. Naloxone (brand name Narcan) is a short-acting opioid antagonist used as an emergency rescue medication to reverse opioid overdoses, while naltrexone is a long-acting antagonist taken on a scheduled basis to prevent relapse. Naloxone works within minutes but wears off quickly, whereas naltrexone provides sustained receptor blockade over hours or weeks depending on the formulation.
How does naltrexone compare to Suboxone?
Naltrexone and Suboxone take fundamentally different approaches to treating opioid dependence. Suboxone contains buprenorphine (a partial opioid agonist) and reduces withdrawal symptoms by mildly activating opioid receptors, while naltrexone fully blocks those receptors without any opioid effect. Patients must be fully detoxed from opioids before starting naltrexone, whereas Suboxone can be initiated during early withdrawal. The best choice depends on individual treatment history and clinical needs.
What is the standard naltrexone dosage?
The standard oral naltrexone dosage for both alcohol and opioid dependence is 50 mg taken once daily. Some providers use an initial dose of 25 mg for the first day to minimize side effects. For Vivitrol, the dosage is 380 mg delivered as a single intramuscular injection once every four weeks. Dosage should not be adjusted without medical supervision.
How much does naltrexone cost and does insurance cover it?
Generic oral naltrexone tablets typically range from $30 to $80 per month without insurance. Vivitrol injections are considerably more expensive, often costing $1,000 to $1,800 per injection without coverage. Most private insurance plans, Medicaid, and Medicare cover naltrexone in both forms, and manufacturer assistance programs are available for eligible patients.
What is low dose naltrexone (LDN)?
Low dose naltrexone (LDN) refers to naltrexone taken at very small doses, typically between 1 mg and 5 mg, far below the standard 50 mg addiction treatment dose. LDN is used off-label for conditions such as chronic pain, fibromyalgia, and certain autoimmune disorders, and it is not an approved treatment for addiction. Patients should not confuse LDN with standard naltrexone therapy for substance use disorders.

About Naltrexone (Vivitrol)

Naltrexone is an opioid antagonist, meaning it binds to the mu-opioid receptors in the brain without activating them. By occupying these receptors, naltrexone effectively blocks the rewarding effects of opioids and reduces the neurochemical reinforcement that drives alcohol cravings. Unlike medications such as methadone or buprenorphine, naltrexone has no potential for abuse or physical dependence because it produces no opioid effect whatsoever.

How Naltrexone Works

When a person taking naltrexone consumes alcohol, the pleasurable dopamine surge that normally reinforces drinking behavior is significantly blunted. For individuals with opioid dependence, naltrexone prevents any ingested opioid from reaching the receptors, rendering opioid use ineffective. This pharmacological mechanism makes naltrexone a cornerstone of medication-assisted treatment (MAT) programs across the country. Naltrexone was first approved by the FDA in 1984 for opioid dependence and received additional approval for alcohol dependence in 1994.

Naltrexone Side Effects

Common side effects include:

  • Nausea, especially during the first few days
  • Headache and dizziness
  • Fatigue and insomnia
  • Joint and muscle pain
  • Decreased appetite and anxiety

Serious side effects are less common but include signs of liver injury such as yellowing of the skin or eyes, dark urine, and persistent abdominal pain. Severe injection site reactions from Vivitrol, including tissue necrosis, have been reported in rare cases. Importantly, naltrexone lowers opioid tolerance over time — if a person discontinues naltrexone and attempts to use opioids at previously tolerated doses, the risk of fatal overdose increases significantly.

Naltrexone for Alcohol Dependence

Naltrexone is one of only three FDA-approved medications for alcohol use disorder, alongside disulfiram (Antabuse) and acamprosate (Campral). For individuals struggling with alcohol dependence, naltrexone reduces heavy drinking days and increases the percentage of days abstinent. The oral formulation, sold under the brand name Revia, is typically prescribed at 50 mg daily and is most effective when combined with behavioral therapy and support groups.

Naltrexone for Opioid Dependence

For opioid dependence, naltrexone serves as a relapse-prevention tool rather than a detox medication. Patients must complete a full opioid detoxification and remain opioid-free for a minimum of 7 to 14 days before beginning naltrexone therapy. Starting naltrexone while opioids are still present can trigger sudden and severe precipitated withdrawal. Once initiated, naltrexone provides a pharmacological safety net — if a patient relapses, naltrexone blocks the drug from producing its usual effects.

Vivitrol: Injectable Naltrexone

Vivitrol is the brand name for naltrexone extended-release injectable suspension, delivering 380 mg in a single intramuscular dose once per month. A healthcare provider injects Vivitrol into the gluteal muscle using a special needle included in the product kit, alternating sides each month. The Vivitrol shot has become increasingly popular because it solves one of the biggest challenges in addiction treatment: medication adherence. Studies show that patients receiving monthly Vivitrol injections are significantly more likely to remain in treatment compared to those prescribed daily oral naltrexone.

Vivitrol Side Effects

Vivitrol shares many side effects with oral naltrexone but carries additional risks related to the injection site. These range from mild tenderness, redness, and swelling to severe complications including induration and in rare cases tissue necrosis requiring surgical intervention. As with oral naltrexone, Vivitrol can affect liver function, and depressed mood and suicidal thoughts have also been reported.

Revia: Oral Naltrexone Brand

Revia is the primary brand name for oral naltrexone hydrochloride tablets in a 50 mg strength. Today, most prescriptions are filled with generic naltrexone, which is bioequivalent and significantly less expensive. The main advantage of oral naltrexone over injectable Vivitrol is lower cost and greater dosing flexibility, but it requires daily compliance, which patients in early recovery frequently struggle with.

Low Dose Naltrexone (LDN)

Low dose naltrexone (LDN) refers to naltrexone prescribed at doses ranging from 0.5 mg to 5 mg — a fraction of the standard 50 mg addiction treatment dose. LDN is used off-label and is not FDA-approved for any condition at these low doses. It is not a treatment for addiction and operates through a fundamentally different mechanism. The theory proposes that a brief, transient blockade of opioid receptors causes a rebound effect that increases the body's natural endorphin production. LDN has been investigated for conditions including fibromyalgia, multiple sclerosis, and Crohn's disease, but large-scale clinical trials are still needed.

Naltrexone Cost and Insurance

Generic oral naltrexone typically costs $30 to $80 per month without insurance. With insurance or discount programs, out-of-pocket cost can fall below $15. Vivitrol injections cost $1,000 to $1,800 without insurance, but most private plans, Medicaid, and Medicare cover it. Alkermes offers the Vivitrol Co-Pay Savings Program for insured patients and a Patient Assistance Program for those without insurance.

Naltrexone Dosage

The standard oral dose is 50 mg once daily, with some providers starting at 25 mg for the first day to minimize side effects. For Vivitrol, the dose is 380 mg as a single intramuscular injection every four weeks. Patients must be opioid-free for a minimum of 7 to 14 days before initiating either formulation.

Naltrexone vs Naloxone: What's the Difference?

Both are opioid antagonists, but they differ in duration and use. Naloxone (Narcan) is a short-acting emergency overdose reversal agent that takes effect within minutes and wears off in 30 to 90 minutes. Naltrexone is a long-acting antagonist for ongoing relapse prevention, providing blockade for 24 hours (oral) or 30 days (Vivitrol). Naloxone is also a component of Suboxone, where it deters injection misuse.

Naltrexone vs Suboxone

Suboxone contains buprenorphine (a partial opioid agonist) that mildly stimulates opioid receptors, reducing cravings and withdrawal. Naltrexone fully blocks receptors with zero agonist activity. Patients must be fully detoxed before starting naltrexone, whereas Suboxone can be initiated during early withdrawal. A landmark 2017 clinical trial (X:BOT) found that among patients who successfully started treatment, relapse rates were similar between Vivitrol and Suboxone.

Naltrexone and Weight Loss

Naltrexone is one of two active ingredients in Contrave (naltrexone/bupropion), an FDA-approved weight management medication. However, naltrexone alone is not approved for weight loss. Some patients undergoing addiction treatment report modest weight changes related to reduced alcohol calories or appetite-suppressing side effects, but naltrexone should not be selected as an addiction medication primarily for weight effects.

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Medically Reviewed Updated May 2026

Reviewed by licensed addiction specialists. Information reflects current clinical guidance.

Sources:SAMHSA·NIDA·CDC

Need immediate help? Call SAMHSA: 1-800-662-4357 (24/7, free)