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Medically Reviewed Content
Updated: October 2026
Sources: SAMHSA, NIDA

Naltrexone and Vivitrol Treatment Centers

Naltrexone is an FDA-approved opioid antagonist medication used to treat both alcohol dependence and opioid use disorder. Available as a daily oral tablet (Revia) or a monthly Vivitrol injection, naltrexone works by blocking opioid receptors in the brain to reduce cravings and prevent relapse. Use our directory to find treatment centers that offer naltrexone-based medication-assisted treatment near you.

Found 6,655 treatment centers offering naltrexone (vivitrol) across the United States.

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ABC Recovery Center Inc

ABC Recovery Center Inc, located in Indio, CA, provides a full spectrum of substance abuse treatment options. This establishment is particularly adept at long-term residential rehabilitation and inpatient detox for adult women. Their approach emphasizes 12-step facilitation, anger management, and cognitive-behavioral therapy, designed for individuals facing co-occurring mental health and substance use issues, including those living with HIV or AIDS. Catering to a diverse age range from young adults to seniors, the center fosters a nurturing setting for women to begin their path to wellness. Known for its dedication to high-quality, evidence-based care, ABC Recovery Center Inc stands as a reliable choice for effective addiction treatment.

ABC Sober Living LLC

ABC Sober Living LLC, located in San Diego, CA, specializes in providing extensive treatment for substance use as well as transitional housing specifically for adult women. The center employs intensive outpatient services that leverage proven methods, including 12-step facilitation, cognitive behavioral therapy, and contingency management. This program is particularly beneficial for individuals who have faced trauma or sexual abuse. With an emphasis on females spanning various age groups, including adults, seniors, and young adults, the center guarantees personalized attention in a nurturing atmosphere. ABC Sober Living LLC is recognized for its dedication to high-quality care and customized treatment plans that meet the distinct requirements of each person on their path to recovery.

ACCESS Blue Island Medical Center

ACCESS Blue Island Medical Center, located in Blue Island, IL, provides outpatient treatment for adults dealing with substance use disorders, particularly those with concurrent severe mental health challenges or emotional issues in children. The facility employs various therapeutic approaches, including cognitive behavioral therapy and the Matrix Model, to deliver holistic support. Tailored programs are available for both men and women, alongside services designed for clients living with HIV or AIDS. Focusing on young adults as well, this center fosters a nurturing atmosphere conducive to recovery. By offering outpatient treatments with methadone, buprenorphine, or naltrexone, ACCESS Blue Island Medical Center emphasizes personalized care for all clients.

ACTS Behavioral Health and

In Lakewood, WA, ACTS Behavioral Health provides comprehensive treatment programs for adults struggling with substance use and co-occurring mental health conditions, as well as for children with serious emotional disturbances. Their services encompass intensive outpatient, outpatient, and regular outpatient levels of care. Utilizing therapeutic approaches such as anger management, brief intervention, and cognitive behavioral therapy, ACTS Behavioral Health delivers tailored support. They offer personalized treatment plans for adults and children, accommodating both male and female clients who are looking for effective addiction recovery and mental health support in a nurturing setting.

AISOL LLC
West Palm Beach, FL

AISOL LLC, situated in West Palm Beach, FL, delivers complete addiction recovery solutions, encompassing both detox and comprehensive substance use treatment. The center features distinct programs designed for adult males, adult females, and individuals managing HIV or AIDS, guaranteeing personalized attention for a broad spectrum of client needs. Their treatment modalities span from hospital-based inpatient detoxification to residential detoxification, ensuring a seamless progression of care. Employing scientifically validated methods such as 12-step facilitation, brief intervention, and cognitive behavioral therapy, AISOL LLC is dedicated to fostering complete well-being. Catering to adult and young adult individuals of all gender identities, AISOL LLC is committed to delivering high-caliber treatment and bespoke encouragement for sustained sobriety.

ADAPT MOTS only Madrone

Madrone, located in Roseburg, OR, delivers extensive treatment for substance abuse and is proficient in addressing co-occurring disorders among both adults and children. This center features adaptable outpatient options, which include intensive outpatient programs and medication-assisted treatment. Emphasizing tools such as 12-step facilitation, anger management, and short interventions, the facility customizes its approach to meet each person's specific needs. It also offers distinct programs for active military members, adult men and women, and services tailored for children and teenagers, ensuring focused care for every individual. With a strong commitment to high-quality treatment and a variety of specialized methods, Madrone is resolute in assisting individuals throughout their recovery process.

AK Add Rehabilitation Services inc

AK Add Rehabilitation Services Inc, situated in Wasilla, AK, provides a full spectrum of care for those battling addiction. Their offerings include intensive outpatient, long-term residential, and standard outpatient services. Treatment modalities employed by the center encompass 12-step facilitation, anger management techniques, and brief intervention strategies. They also offer specialized support for adult men, adult women, and individuals affected by intimate partner or domestic violence. Dedicated to addressing dual diagnoses of substance use and mental health conditions, this facility supports adults and young adults of all genders with tailored treatment and assistance.

ALPHA Behavioral Health Center

ALPHA Behavioral Health Center, located in Camden, SC, provides targeted treatment for substance use via both outpatient and traditional outpatient services. Their comprehensive approach encompasses anger management, brief interventions, and cognitive-behavioral therapy. The center offers customized programs designed for adolescents, adult men, and adult women, addressing the needs of both adults and younger clients. Emphasizing personalized care, ALPHA Behavioral Health Center is open to all clients, regardless of gender, who are in pursuit of effective rehabilitation solutions. The center is committed to offering top-notch treatment options through a variety of specialized programs aimed at accommodating the unique requirements of each individual.

ACTS Behavioral Health and

Situated in Lynnwood, WA, ACTS Behavioral Health specializes in outpatient services for adults facing substance use challenges alongside significant mental health disorders, as well as for children experiencing serious emotional disturbances. Utilizing evidence-based methodologies such as anger management, brief intervention, and cognitive behavioral therapy, this center develops personalized programs for each individual. Catering to a diverse range of clients, including adults and children/adolescents of all genders, ACTS Behavioral Health is committed to delivering high-quality care through customized treatment plans. If you or someone you know is in need of thorough and effective addiction support, this program may be the ideal option for you.

AGS Programs LLC
Baltimore, MD

AGS Programs LLC located in Baltimore, MD, provides focused rehabilitation solutions for adult men in need of substance abuse treatment. This center offers various treatment options, which encompass long-term residential care, outpatient programs, and standard outpatient services. The therapeutic methods employed include cognitive behavioral therapy, anger management, and the Matrix Model. Additionally, AGS Programs LLC addresses the needs of distinct groups, including active duty military members, adult males, and those affected by intimate partner violence. With programming designed for adults, seniors, and young adults, the facility guarantees a thorough and individualized recovery experience for male clients.

AGS Programs LLC
Gwynn Oak, MD

AGS Programs LLC, located in Gwynn Oak, MD, delivers a variety of rehabilitation services specifically designed for men facing challenges with substance use. The center offers a spectrum of treatment options including long-term residential programs, outpatient care, and routine outpatient services, all of which utilize cognitive behavioral therapy, anger management techniques, and the Matrix Model. AGS Programs LLC is dedicated to providing specialized support for active military personnel, adult males, and those who have endured intimate partner or domestic violence. This facility serves a diverse range of individuals, from adults to seniors and young adults, fostering a nurturing environment for male clients in need of comprehensive addiction recovery and transitional housing assistance.

AGS Programs LLC
Baltimore, MD

AGS Programs LLC, located in Baltimore, MD, delivers expert recovery support for individuals grappling with addiction and concurrent mental health challenges, catering to both younger and adult demographics. Their comprehensive offerings include robust intensive outpatient programs, structured day treatment services, and partial hospitalization options. Employing evidence-based approaches such as anger management, cognitive behavioral therapy, and the Matrix Model, the center crafts individualized recovery journeys. They also feature distinct treatment pathways for active military personnel, teenagers, and adult males, guaranteeing focused interventions. AGS Programs LLC provides compassionate and customized assistance to all clients, regardless of gender or age.

AGS Programs LLC
Baltimore, MD

AGS Programs LLC in Baltimore, MD delivers tailored addiction recovery support exclusively for women. Their offerings include extended residential stays, day treatment, and standard outpatient services. Employing approaches such as anger management, cognitive behavioral therapy, and the Matrix Model, the center ensures thorough recovery assistance. Specialized care is available for active military members, adult women, and survivors of domestic abuse. Catering to adults, seniors, and young adults, AGS Programs LLC focuses on the distinct requirements of female individuals. Clients can anticipate high-quality treatment and successful rehabilitation methodologies at this establishment.

AIM Advaita Integrated Medicine

AIM Advaita Integrated Medicine in Raleigh, NC, is dedicated to providing thorough substance abuse care and targeted support for those facing concurrent mental health challenges. They offer intensive outpatient, outpatient services, and medication-assisted treatment including methadone, buprenorphine, or naltrexone. Employing proven methods such as anger management, CBT, and brief interventions, the center serves adult men, adult women, and individuals with co-occurring disorders. Serving adults and adolescents, AIM Advaita Integrated Medicine delivers individualized attention to all clients, prioritizing effective and customized treatment strategies.

ALPHA Behavioral Health Center

ALPHA Behavioral Health Center in Chesterfield, SC, delivers outpatient support for individuals grappling with substance use issues, serving both young people and adults. The center employs proven therapeutic methods like anger control strategies, concise intervention techniques, and cognitive behavioral therapy within its regular outpatient services. They offer distinct programs designed for adult men, adult women, and adolescents, ensuring that a wide range of people receive relevant care. Anyone needing effective substance use treatment in a nurturing setting may find ALPHA Behavioral Health Center to be a valuable partner in their path to recovery.

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Elberton, GA

ABHS, situated in Elberton, GA, provides a complete spectrum of addiction recovery services for both adults and young people. Their offerings include detoxification, drug and alcohol dependency treatment, and sober living accommodations within a nurturing atmosphere. This facility, which features intensive outpatient programs and cognitive behavioral therapy, excels in anger control and short-term intervention strategies. ABHS serves adult men and women, along with individuals who have faced trauma. By customizing programs for various age demographics and genders, the center guarantees individualized support for everyone pursuing sobriety. Rely on ABHS for excellent service and successful treatment approaches in your path to recovery.

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Queensbury, NY

Situated in Queensbury, NY, ACCA Quaker Road stands out as a premier rehabilitation facility dedicated to substance use recovery for adult males. The center offers both long-term and 24-hour residential care, creating a nurturing atmosphere for those on the path to recovery. By employing evidence-based methods like anger management, cognitive behavioral therapy, and motivational incentives, ACCA Quaker Road personalizes its treatment plans to suit the distinct requirements of each individual. Catering to adult men, seniors, and younger adult males, the center is committed to providing exceptional care and support during the recovery process.

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Situated in Bloomingdale, IL, the ACCESS Martin T Russo Family Hlth Ctr provides expert outpatient care for individuals dealing with substance use and co-occurring mental health challenges, serving both adults and children. The facility offers various treatment options, including outpatient programs featuring methadone, buprenorphine, and naltrexone, alongside standard outpatient services. It employs proven strategies such as brief intervention, the Matrix Model, and motivational interviewing to ensure effective support. Designed to meet the specific needs of adult men, women, and individuals living with HIV or AIDS, the center caters to both adult and young adult populations of all genders. Committed to delivering high-quality, personalized care, this center stands as a symbol of hope for those in need of thorough rehabilitation options.

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Baltimore, MD

Located in Baltimore, MD, AKT Healthcare Inc provides extensive rehabilitation services designed for adults and seniors facing challenges with substance abuse and co-existing mental health issues. This center specializes in long-term residential care, which encompasses detox services and round-the-clock assistance, employing evidence-based methods like 12-step programs and anger management techniques. Tailored programs are available for youth, individuals impacted by intimate partner violence, domestic violence, and sexual abuse. AKT Healthcare Inc emphasizes personalized treatment plans, ensuring that both male and female clients receive dedicated care. Discover empathetic and impactful rehabilitation at this esteemed facility.

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Reidsville, NC

ALEF Behavioral Group, located in Reidsville, NC, delivers tailored outpatient addiction recovery services for adults and young adults. Their offerings include intensive outpatient care, standard outpatient services, and medication-assisted treatment utilizing methadone, buprenorphine, or naltrexone. The center employs strategies such as 12-step facilitation, anger management, and brief intervention, all customized to meet individual client requirements. ALEF Behavioral Group extends specialized care to pregnant and postpartum women, and maintains distinct programs for male and female clients to foster a supportive, gender-sensitive recovery atmosphere. Opt for ALEF Behavioral Group for reliable and impactful substance use disorder treatment.

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ALEF Behavioral Group Reidsville, located in Reidsville, NC, specializes in providing tailored treatment for substance use disorders for both adults and young adults. The facility features intensive outpatient programs, standard outpatient services, and options for methadone/buprenorphine or naltrexone treatment. Emphasizing 12-step support, anger management, and brief intervention techniques, the center serves clients of all genders. Additionally, it offers specialized programs for pregnant and postpartum women, ensuring holistic support for every individual. Committed to high-quality care and personalized treatment plans, this center is an essential resource for effective addiction recovery in the Reidsville region.

Frequently Asked Questions

What is naltrexone and how does it work?
Naltrexone is an opioid antagonist medication approved by the FDA to treat both alcohol use disorder and opioid dependence. It works by binding to opioid receptors in the brain, blocking the euphoric and sedative effects of opioids and reducing alcohol cravings. Naltrexone is available as an oral tablet (brand name Revia) and as a monthly injection (brand name Vivitrol).
What are the most common naltrexone side effects?
The most common naltrexone side effects include nausea, headache, dizziness, fatigue, insomnia, and anxiety. Some patients also experience joint or muscle pain, decreased appetite, and stomach cramps. Most side effects are mild and tend to diminish within the first few weeks of treatment. Serious but rare side effects include liver damage, so physicians typically monitor liver function during treatment.
What is Vivitrol and how is the injection administered?
Vivitrol is the brand name for extended-release naltrexone, delivered as a once-monthly intramuscular injection. The Vivitrol injection is administered by a healthcare provider into the gluteal muscle and slowly releases naltrexone over approximately 30 days. This eliminates the need for daily pill compliance, making it a preferred option for many patients in recovery from alcohol or opioid dependence.
What is the difference between naltrexone and naloxone?
Although their names sound similar, naltrexone and naloxone serve different purposes. Naloxone (brand name Narcan) is a short-acting opioid antagonist used as an emergency rescue medication to reverse opioid overdoses, while naltrexone is a long-acting antagonist taken on a scheduled basis to prevent relapse. Naloxone works within minutes but wears off quickly, whereas naltrexone provides sustained receptor blockade over hours or weeks depending on the formulation.
How does naltrexone compare to Suboxone?
Naltrexone and Suboxone take fundamentally different approaches to treating opioid dependence. Suboxone contains buprenorphine (a partial opioid agonist) and reduces withdrawal symptoms by mildly activating opioid receptors, while naltrexone fully blocks those receptors without any opioid effect. Patients must be fully detoxed from opioids before starting naltrexone, whereas Suboxone can be initiated during early withdrawal. The best choice depends on individual treatment history and clinical needs.
What is the standard naltrexone dosage?
The standard oral naltrexone dosage for both alcohol and opioid dependence is 50 mg taken once daily. Some providers use an initial dose of 25 mg for the first day to minimize side effects. For Vivitrol, the dosage is 380 mg delivered as a single intramuscular injection once every four weeks. Dosage should not be adjusted without medical supervision.
How much does naltrexone cost and does insurance cover it?
Generic oral naltrexone tablets typically range from $30 to $80 per month without insurance. Vivitrol injections are considerably more expensive, often costing $1,000 to $1,800 per injection without coverage. Most private insurance plans, Medicaid, and Medicare cover naltrexone in both forms, and manufacturer assistance programs are available for eligible patients.
What is low dose naltrexone (LDN)?
Low dose naltrexone (LDN) refers to naltrexone taken at very small doses, typically between 1 mg and 5 mg, far below the standard 50 mg addiction treatment dose. LDN is used off-label for conditions such as chronic pain, fibromyalgia, and certain autoimmune disorders, and it is not an approved treatment for addiction. Patients should not confuse LDN with standard naltrexone therapy for substance use disorders.

About Naltrexone (Vivitrol)

Naltrexone is an opioid antagonist, meaning it binds to the mu-opioid receptors in the brain without activating them. By occupying these receptors, naltrexone effectively blocks the rewarding effects of opioids and reduces the neurochemical reinforcement that drives alcohol cravings. Unlike medications such as methadone or buprenorphine, naltrexone has no potential for abuse or physical dependence because it produces no opioid effect whatsoever.

How Naltrexone Works

When a person taking naltrexone consumes alcohol, the pleasurable dopamine surge that normally reinforces drinking behavior is significantly blunted. For individuals with opioid dependence, naltrexone prevents any ingested opioid from reaching the receptors, rendering opioid use ineffective. This pharmacological mechanism makes naltrexone a cornerstone of medication-assisted treatment (MAT) programs across the country. Naltrexone was first approved by the FDA in 1984 for opioid dependence and received additional approval for alcohol dependence in 1994.

Naltrexone Side Effects

Common side effects include:

  • Nausea, especially during the first few days
  • Headache and dizziness
  • Fatigue and insomnia
  • Joint and muscle pain
  • Decreased appetite and anxiety

Serious side effects are less common but include signs of liver injury such as yellowing of the skin or eyes, dark urine, and persistent abdominal pain. Severe injection site reactions from Vivitrol, including tissue necrosis, have been reported in rare cases. Importantly, naltrexone lowers opioid tolerance over time — if a person discontinues naltrexone and attempts to use opioids at previously tolerated doses, the risk of fatal overdose increases significantly.

Naltrexone for Alcohol Dependence

Naltrexone is one of only three FDA-approved medications for alcohol use disorder, alongside disulfiram (Antabuse) and acamprosate (Campral). For individuals struggling with alcohol dependence, naltrexone reduces heavy drinking days and increases the percentage of days abstinent. The oral formulation, sold under the brand name Revia, is typically prescribed at 50 mg daily and is most effective when combined with behavioral therapy and support groups.

Naltrexone for Opioid Dependence

For opioid dependence, naltrexone serves as a relapse-prevention tool rather than a detox medication. Patients must complete a full opioid detoxification and remain opioid-free for a minimum of 7 to 14 days before beginning naltrexone therapy. Starting naltrexone while opioids are still present can trigger sudden and severe precipitated withdrawal. Once initiated, naltrexone provides a pharmacological safety net — if a patient relapses, naltrexone blocks the drug from producing its usual effects.

Vivitrol: Injectable Naltrexone

Vivitrol is the brand name for naltrexone extended-release injectable suspension, delivering 380 mg in a single intramuscular dose once per month. A healthcare provider injects Vivitrol into the gluteal muscle using a special needle included in the product kit, alternating sides each month. The Vivitrol shot has become increasingly popular because it solves one of the biggest challenges in addiction treatment: medication adherence. Studies show that patients receiving monthly Vivitrol injections are significantly more likely to remain in treatment compared to those prescribed daily oral naltrexone.

Vivitrol Side Effects

Vivitrol shares many side effects with oral naltrexone but carries additional risks related to the injection site. These range from mild tenderness, redness, and swelling to severe complications including induration and in rare cases tissue necrosis requiring surgical intervention. As with oral naltrexone, Vivitrol can affect liver function, and depressed mood and suicidal thoughts have also been reported.

Revia: Oral Naltrexone Brand

Revia is the primary brand name for oral naltrexone hydrochloride tablets in a 50 mg strength. Today, most prescriptions are filled with generic naltrexone, which is bioequivalent and significantly less expensive. The main advantage of oral naltrexone over injectable Vivitrol is lower cost and greater dosing flexibility, but it requires daily compliance, which patients in early recovery frequently struggle with.

Low Dose Naltrexone (LDN)

Low dose naltrexone (LDN) refers to naltrexone prescribed at doses ranging from 0.5 mg to 5 mg — a fraction of the standard 50 mg addiction treatment dose. LDN is used off-label and is not FDA-approved for any condition at these low doses. It is not a treatment for addiction and operates through a fundamentally different mechanism. The theory proposes that a brief, transient blockade of opioid receptors causes a rebound effect that increases the body's natural endorphin production. LDN has been investigated for conditions including fibromyalgia, multiple sclerosis, and Crohn's disease, but large-scale clinical trials are still needed.

Naltrexone Cost and Insurance

Generic oral naltrexone typically costs $30 to $80 per month without insurance. With insurance or discount programs, out-of-pocket cost can fall below $15. Vivitrol injections cost $1,000 to $1,800 without insurance, but most private plans, Medicaid, and Medicare cover it. Alkermes offers the Vivitrol Co-Pay Savings Program for insured patients and a Patient Assistance Program for those without insurance.

Naltrexone Dosage

The standard oral dose is 50 mg once daily, with some providers starting at 25 mg for the first day to minimize side effects. For Vivitrol, the dose is 380 mg as a single intramuscular injection every four weeks. Patients must be opioid-free for a minimum of 7 to 14 days before initiating either formulation.

Naltrexone vs Naloxone: What's the Difference?

Both are opioid antagonists, but they differ in duration and use. Naloxone (Narcan) is a short-acting emergency overdose reversal agent that takes effect within minutes and wears off in 30 to 90 minutes. Naltrexone is a long-acting antagonist for ongoing relapse prevention, providing blockade for 24 hours (oral) or 30 days (Vivitrol). Naloxone is also a component of Suboxone, where it deters injection misuse.

Naltrexone vs Suboxone

Suboxone contains buprenorphine (a partial opioid agonist) that mildly stimulates opioid receptors, reducing cravings and withdrawal. Naltrexone fully blocks receptors with zero agonist activity. Patients must be fully detoxed before starting naltrexone, whereas Suboxone can be initiated during early withdrawal. A landmark 2017 clinical trial (X:BOT) found that among patients who successfully started treatment, relapse rates were similar between Vivitrol and Suboxone.

Naltrexone and Weight Loss

Naltrexone is one of two active ingredients in Contrave (naltrexone/bupropion), an FDA-approved weight management medication. However, naltrexone alone is not approved for weight loss. Some patients undergoing addiction treatment report modest weight changes related to reduced alcohol calories or appetite-suppressing side effects, but naltrexone should not be selected as an addiction medication primarily for weight effects.

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Medically Reviewed Updated October 2026

Reviewed by licensed addiction specialists. Information reflects current clinical guidance.

Sources:SAMHSA·NIDA·CDC

Need immediate help? Call SAMHSA: 1-800-662-4357 (24/7, free)