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Medically Reviewed Content
Updated: October 2026
Sources: SAMHSA, NIDA

Naltrexone and Vivitrol Treatment Centers

Naltrexone is an FDA-approved opioid antagonist medication used to treat both alcohol dependence and opioid use disorder. Available as a daily oral tablet (Revia) or a monthly Vivitrol injection, naltrexone works by blocking opioid receptors in the brain to reduce cravings and prevent relapse. Use our directory to find treatment centers that offer naltrexone-based medication-assisted treatment near you.

Found 6,655 treatment centers offering naltrexone (vivitrol) across the United States.

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AMS of Delaware LLC
Rehoboth Beach, DE

AMS of Delaware LLC, located in Rehoboth Beach, DE, delivers thorough addiction recovery services for adults and young adults. Their expertise lies in detoxification and substance abuse treatment, offering intensive outpatient and standard outpatient options, including outpatient detox. Employing techniques like anger management, brief intervention, and cognitive behavioral therapy, the center customizes care plans to suit each person's unique journey. AMS of Delaware LLC also provides dedicated programs for adult men, adult women, and individuals facing co-occurring mental health and substance use challenges. Prioritizing excellent care, this establishment fosters a nurturing setting for those pursuing freedom from addiction.

AMS of Wisconsin LLC

AMS of Wisconsin LLC, located in Onalaska, WI, provides a wide array of treatments aimed at detoxification, substance abuse recovery, and addressing co-occurring mental health issues for both adults and children. Their programs include intensive outpatient and outpatient services that utilize evidence-based methods such as cognitive behavioral therapy, anger management, and brief interventions. This center supports men and women, including those who have faced domestic violence or intimate partner abuse. With dedicated offerings for adults and seniors of all genders, AMS of Wisconsin LLC is committed to delivering personalized care, making it an essential facility for individuals seeking effective rehabilitation options in the Onalaska region.

AMS of Wisconsin LLC

AMS of Wisconsin LLC, located in Oshkosh, WI, provides community-based withdrawal management and addiction rehabilitation services. Employing techniques such as dialectical behavior therapy, motivational interviewing, and trauma-informed care, this establishment serves adult men and women, older adults, and individuals affected by intimate partner or domestic violence. Through tailored interventions for various demographics, AMS of Wisconsin LLC delivers personalized support to address unique requirements. For those requiring outpatient methadone, buprenorphine, or naltrexone therapies, or standard outpatient care, clients can anticipate effective, scientifically supported treatment at this facility.

ARC Addiction Recovery Care
Saint Catharine, KY

Situated in Saint Catharine, KY, ARC Addiction Recovery Care specializes in extensive treatment for substance use disorders specifically designed for adult and senior males. This center offers a range of programs including intensive outpatient, long-term residential, and outpatient options that are customized to meet the unique needs of each individual. ARC employs various methodologies such as 12-step facilitation, anger management techniques, and brief intervention strategies to aid in the recovery process. By emphasizing tailored care, this facility guarantees a personalized experience for its clients. ARC Addiction Recovery Care is recognized for its dedication to high-quality treatment and targeted programs aimed at assisting male adults and seniors facing addiction challenges.

ARC Addiction Recovery Care
Saint Catharine, KY

ARC Addiction Recovery Care in Saint Catharine, KY, provides complete substance abuse recovery for adult and senior men. They offer various treatment plans like intensive outpatient, extended residential stays, and standard outpatient services. Using methods such as 12-step facilitation, anger management, and brief intervention, ARC ensures each person receives personalized support. The center excels in crafting customized plans for every client, making it a perfect place for those needing focused help in a caring setting. ARC Addiction Recovery Care is committed to delivering excellent recovery support for sustained sobriety for you or someone you care about.

ARC Addiction Recovery Care
Saint Catharine, KY

Nestled in Saint Catharine, KY, ARC Addiction Recovery Care provides specialized substance abuse treatment for adult and elderly men. Emphasizing personalized support, the center offers intensive outpatient, extended residential stays, and outpatient services. They employ methods like 12-step integration, emotional regulation techniques, and brief therapeutic interventions to deliver a complete recovery journey. What makes ARC Addiction Recovery Care distinctive is their commitment to custom-fit care, addressing the unique circumstances of every individual. This facility is an excellent choice for younger men looking for effective addiction rehabilitation, as ARC Addiction Recovery Care is devoted to guiding them toward a life free from addiction.

ARC Counseling Centers

ARC Counseling Centers, situated in Louisa, KY, provides dedicated substance use rehabilitation services tailored for adults and young adults within a nurturing atmosphere. The center features various treatment options, including intensive outpatient, long-term residential, and outpatient programs, all designed to meet the specific needs of each client. Employing methodologies such as 12-step facilitation, anger management, and brief interventions, ARC Counseling Centers promotes a well-rounded recovery experience. Their commitment to personalized care and attention to gender-specific requirements differentiates them from other facilities. Serving both male and female individuals, this center emphasizes high-quality, customized support for those on their path to overcoming addiction.

ARC Counseling Centers

Situated in Louisa, KY, ARC Counseling Centers specializes in substance use rehabilitation for women of all ages, including adults, seniors, and young adults. The center offers a range of programs, including intensive outpatient services, long-term residential options, and outpatient care, all customized to meet the specific needs of each client. Incorporating techniques such as 12-step programs, anger management, and brief interventions, ARC Counseling Centers provides thorough and effective treatment. This facility is recognized for its dedication to crafting personalized recovery plans, ensuring that each individual receives the tailored support they require. If you are in search of exceptional addiction treatment that prioritizes individualized attention, ARC Counseling Centers is a great option for your recovery path.

ARCH Detox
Aurora, CO

ARCH Detox, situated in Aurora, CO, provides outpatient services for individuals of all ages grappling with substance use and mental health challenges. Their expertise lies in addressing dual diagnoses, encompassing co-occurring substance use disorders and severe mental health conditions in adults, and serious emotional disturbances in children. Utilizing evidence-based approaches like cognitive behavioral therapy, anger management, and brief intervention, ARCH Detox delivers personalized treatment plans. They also offer dedicated programs for active duty military, adult men, and adult women, welcoming both male and female clients on their journey to recovery and improved well-being.

ARS Of Lancaster LP
Lancaster, PA

ARS Of Lancaster LP, located in Lancaster, PA, provides a wide range of addiction rehabilitation services for both adults and young adults. The center focuses on detoxification and treatment for substance use, offering intensive outpatient and standard outpatient programs, inclusive of outpatient detox services. ARS Of Lancaster LP employs evidence-based methods like cognitive behavioral therapy and contingency management, customizing treatment plans to meet the unique needs of each individual. With specialized programs available for active duty military personnel, adult men, and adult women, the center is committed to delivering tailored care. Serving clients of all genders, ARS Of Lancaster LP is dedicated to facilitating recovery journeys with high-quality support.

AMS of Wisconsin LLC
Janesville, WI

AMS of Wisconsin LLC in Janesville, WI, provides outpatient services for detox and substance use disorder treatment. Their approach incorporates techniques like anger management, brief intervention, and cognitive behavioral therapy to foster recovery. The center offers distinct programs for active military, adult men, and adult women, addressing a wide range of individuals. Serving adults and seniors of all genders, AMS of Wisconsin LLC delivers personalized, high-quality care. Clients can anticipate thorough assistance and proven methods for detoxification and substance use recovery at this esteemed facility.

ARS of Aberdeen
Aberdeen, MD

Situated in Aberdeen, MD, ARS of Aberdeen specializes in extensive treatment for substance use disorders targeting both adults and young adults. The center provides various levels of care including intensive outpatient programs, regular outpatient services, and treatments that utilize methadone/buprenorphine or naltrexone. Implementing research-backed methods such as cognitive behavioral therapy, motivational incentives, and the Matrix Model, ARS of Aberdeen serves both men and women, as well as individuals facing co-occurring mental health and substance use challenges. With tailored programs designed for diverse populations and a commitment to high-quality treatment, ARS of Aberdeen is focused on aiding individuals in their recovery journey.

ARS of Aberdeen LLC

ARS of Aberdeen LLC in Aberdeen, MD, provides a full spectrum of substance abuse treatment, including intensive outpatient, standard outpatient, and medication-assisted treatment options with methadone, buprenorphine, or naltrexone. Their therapeutic approach integrates cognitive behavioral therapy, motivational interviewing, and relapse prevention strategies, all delivered within a personalized framework designed to meet individual needs. The center welcomes adults and young adults of all genders, offering tailored support for a wide range of recovery journeys. ARS of Aberdeen LLC is dedicated to delivering high-quality, evidence-based care in a nurturing setting for individuals pursuing recovery. Discover individualized support and proven rehabilitation strategies at this location.

ARC
Ashland, KY

ARC, situated in Ashland, KY, delivers targeted substance abuse therapy for adults and emerging adults, utilizing intensive outpatient, outpatient, and day treatment services. Emphasizing personalized attention, the facility incorporates 12-step facilitation, anger management, and brief intervention techniques to cater to diverse requirements. ARC distinguishes itself through its customized programs crafted for both male and female individuals, fostering a nurturing atmosphere. The center's dedication to high-caliber care and bespoke treatment strategies positions it as a premier option for those pursuing impactful and thorough recovery assistance.

ARS New Castle
New Castle, DE

ARS New Castle, located in New Castle, DE, specializes in a wide range of substance use treatment and provides particular attention to adults facing both substance use disorders and significant mental health challenges, as well as addressing emotional issues in children. The center offers various treatment formats, including intensive outpatient care, outpatient programs, and options involving methadone, buprenorphine, or naltrexone. Utilizing research-backed methods like cognitive behavioral therapy and contingency management, ARS New Castle tailors its services to meet the unique needs of active duty military members and both men and women. With a focus on delivering exceptional care, the facility is recognized for its array of treatment options and personalized recovery paths.

ANEW Chemical Health Services

ANEW Chemical Health Services in Saint Paul, MN provides extensive support for individuals battling substance use, along with targeted assistance for those facing co-occurring severe mental health challenges. This center delivers robust outpatient, extended residential, and standard outpatient options designed for adults and young adults. By incorporating principles of 12-step recovery, anger management techniques, and cognitive behavioral therapy, ANEW Chemical Health Services presents a distinct recovery model. They also feature specialized services for adult women, individuals who have experienced intimate partner violence, domestic abuse, and sexual trauma. The center's dedication to gender-specific treatment for women fosters a nurturing and secure atmosphere conducive to healing. Patients can anticipate receiving superior, personalized care to aid them in their path to wellness and lasting sobriety.

ARC Counseling Centers

ARC Counseling Centers, situated in Tyner, Kentucky, is dedicated to providing targeted substance abuse rehabilitation for adult women, seniors, and young women. They offer a range of services, including intensive outpatient, extended residential stays, and outpatient care, all adapted to each person's specific requirements. The facility employs strategies such as 12-step support, emotional regulation training, and brief counseling techniques to foster a thorough and successful path to recovery. A distinguishing feature of ARC Counseling Centers is their personalized care model, which prioritizes individualized attention and treatment plans. For individuals in search of effective addiction treatment within a nurturing setting, this establishment is committed to fostering enduring sobriety and overall well-being.

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New Haven, CT

Situated in New Haven, CT, APT Foundation Inc delivers extensive treatment for substance use disorders, catering to both adults and children/adolescents facing significant mental health challenges or emotional issues. The center offers a range of treatment modalities, including intensive outpatient, outpatient, and options featuring methadone/buprenorphine/naltrexone. With dedicated programs aimed at active military personnel, adult men, and women, APT Foundation Inc customizes its services to meet the distinct needs of each individual. By employing techniques such as 12-step facilitation, anger management, and brief therapeutic interventions, the facility promotes a well-rounded approach to recovery. Committed to high-quality care, APT Foundation Inc serves as a reputable option for individuals in pursuit of impactful rehabilitation solutions.

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New Haven, CT

APT Foundation Inc in New Haven, CT, delivers targeted substance use care for adults managing co-occurring mental health issues, as well as for children with emotional disturbances. The center offers diverse residential recovery options, including extended, round-the-clock, and brief placements. Their therapeutic methods incorporate 12-step engagement, emotional regulation skills, and concise counseling. Specialized services are available for active military personnel, adult women, and survivors of domestic abuse. APT Foundation Inc supports adults, older adults, and younger adults, with a particular emphasis on women. Dedicated to high-quality support, this establishment offers a holistic and nurturing setting for individuals pursuing healing from addiction and mental health concerns.

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New Haven, CT

The APT Foundation Inc, situated in New Haven, CT, provides extensive substance abuse treatment options for adults and young adults. They are particularly skilled in addressing dual diagnoses of substance use disorders and significant mental health conditions. The facility offers various levels of care, including extended stays, shorter programs, and 24-hour residential services. Their therapeutic approaches include 12-step facilitation, anger management training, and brief intervention strategies. The APT Foundation Inc serves adult men, women, and active duty military members. By developing personalized treatment strategies and tailored programs for diverse age groups and genders, they deliver superior recovery and rehabilitation support to everyone in their care.

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Kingston Springs, TN

Situated in Kingston Springs, TN, ARCH Academy delivers extensive treatment for substance use disorders specifically designed for adult men in a nurturing atmosphere. The center offers a variety of programs including intensive outpatient, long-term residential, and outpatient services, incorporating methods such as 12-step support, anger management, and brief interventions. While ARCH Academy primarily focuses on adolescent care, it also serves children, seniors, and adults. Prioritizing high-quality care and personalized treatment strategies, this center is committed to assisting clients in achieving sustainable recovery. For those seeking specialized addiction treatment in a male-only environment, ARCH Academy is an excellent choice for a customized rehabilitation journey.

Frequently Asked Questions

What is naltrexone and how does it work?
Naltrexone is an opioid antagonist medication approved by the FDA to treat both alcohol use disorder and opioid dependence. It works by binding to opioid receptors in the brain, blocking the euphoric and sedative effects of opioids and reducing alcohol cravings. Naltrexone is available as an oral tablet (brand name Revia) and as a monthly injection (brand name Vivitrol).
What are the most common naltrexone side effects?
The most common naltrexone side effects include nausea, headache, dizziness, fatigue, insomnia, and anxiety. Some patients also experience joint or muscle pain, decreased appetite, and stomach cramps. Most side effects are mild and tend to diminish within the first few weeks of treatment. Serious but rare side effects include liver damage, so physicians typically monitor liver function during treatment.
What is Vivitrol and how is the injection administered?
Vivitrol is the brand name for extended-release naltrexone, delivered as a once-monthly intramuscular injection. The Vivitrol injection is administered by a healthcare provider into the gluteal muscle and slowly releases naltrexone over approximately 30 days. This eliminates the need for daily pill compliance, making it a preferred option for many patients in recovery from alcohol or opioid dependence.
What is the difference between naltrexone and naloxone?
Although their names sound similar, naltrexone and naloxone serve different purposes. Naloxone (brand name Narcan) is a short-acting opioid antagonist used as an emergency rescue medication to reverse opioid overdoses, while naltrexone is a long-acting antagonist taken on a scheduled basis to prevent relapse. Naloxone works within minutes but wears off quickly, whereas naltrexone provides sustained receptor blockade over hours or weeks depending on the formulation.
How does naltrexone compare to Suboxone?
Naltrexone and Suboxone take fundamentally different approaches to treating opioid dependence. Suboxone contains buprenorphine (a partial opioid agonist) and reduces withdrawal symptoms by mildly activating opioid receptors, while naltrexone fully blocks those receptors without any opioid effect. Patients must be fully detoxed from opioids before starting naltrexone, whereas Suboxone can be initiated during early withdrawal. The best choice depends on individual treatment history and clinical needs.
What is the standard naltrexone dosage?
The standard oral naltrexone dosage for both alcohol and opioid dependence is 50 mg taken once daily. Some providers use an initial dose of 25 mg for the first day to minimize side effects. For Vivitrol, the dosage is 380 mg delivered as a single intramuscular injection once every four weeks. Dosage should not be adjusted without medical supervision.
How much does naltrexone cost and does insurance cover it?
Generic oral naltrexone tablets typically range from $30 to $80 per month without insurance. Vivitrol injections are considerably more expensive, often costing $1,000 to $1,800 per injection without coverage. Most private insurance plans, Medicaid, and Medicare cover naltrexone in both forms, and manufacturer assistance programs are available for eligible patients.
What is low dose naltrexone (LDN)?
Low dose naltrexone (LDN) refers to naltrexone taken at very small doses, typically between 1 mg and 5 mg, far below the standard 50 mg addiction treatment dose. LDN is used off-label for conditions such as chronic pain, fibromyalgia, and certain autoimmune disorders, and it is not an approved treatment for addiction. Patients should not confuse LDN with standard naltrexone therapy for substance use disorders.

About Naltrexone (Vivitrol)

Naltrexone is an opioid antagonist, meaning it binds to the mu-opioid receptors in the brain without activating them. By occupying these receptors, naltrexone effectively blocks the rewarding effects of opioids and reduces the neurochemical reinforcement that drives alcohol cravings. Unlike medications such as methadone or buprenorphine, naltrexone has no potential for abuse or physical dependence because it produces no opioid effect whatsoever.

How Naltrexone Works

When a person taking naltrexone consumes alcohol, the pleasurable dopamine surge that normally reinforces drinking behavior is significantly blunted. For individuals with opioid dependence, naltrexone prevents any ingested opioid from reaching the receptors, rendering opioid use ineffective. This pharmacological mechanism makes naltrexone a cornerstone of medication-assisted treatment (MAT) programs across the country. Naltrexone was first approved by the FDA in 1984 for opioid dependence and received additional approval for alcohol dependence in 1994.

Naltrexone Side Effects

Common side effects include:

  • Nausea, especially during the first few days
  • Headache and dizziness
  • Fatigue and insomnia
  • Joint and muscle pain
  • Decreased appetite and anxiety

Serious side effects are less common but include signs of liver injury such as yellowing of the skin or eyes, dark urine, and persistent abdominal pain. Severe injection site reactions from Vivitrol, including tissue necrosis, have been reported in rare cases. Importantly, naltrexone lowers opioid tolerance over time — if a person discontinues naltrexone and attempts to use opioids at previously tolerated doses, the risk of fatal overdose increases significantly.

Naltrexone for Alcohol Dependence

Naltrexone is one of only three FDA-approved medications for alcohol use disorder, alongside disulfiram (Antabuse) and acamprosate (Campral). For individuals struggling with alcohol dependence, naltrexone reduces heavy drinking days and increases the percentage of days abstinent. The oral formulation, sold under the brand name Revia, is typically prescribed at 50 mg daily and is most effective when combined with behavioral therapy and support groups.

Naltrexone for Opioid Dependence

For opioid dependence, naltrexone serves as a relapse-prevention tool rather than a detox medication. Patients must complete a full opioid detoxification and remain opioid-free for a minimum of 7 to 14 days before beginning naltrexone therapy. Starting naltrexone while opioids are still present can trigger sudden and severe precipitated withdrawal. Once initiated, naltrexone provides a pharmacological safety net — if a patient relapses, naltrexone blocks the drug from producing its usual effects.

Vivitrol: Injectable Naltrexone

Vivitrol is the brand name for naltrexone extended-release injectable suspension, delivering 380 mg in a single intramuscular dose once per month. A healthcare provider injects Vivitrol into the gluteal muscle using a special needle included in the product kit, alternating sides each month. The Vivitrol shot has become increasingly popular because it solves one of the biggest challenges in addiction treatment: medication adherence. Studies show that patients receiving monthly Vivitrol injections are significantly more likely to remain in treatment compared to those prescribed daily oral naltrexone.

Vivitrol Side Effects

Vivitrol shares many side effects with oral naltrexone but carries additional risks related to the injection site. These range from mild tenderness, redness, and swelling to severe complications including induration and in rare cases tissue necrosis requiring surgical intervention. As with oral naltrexone, Vivitrol can affect liver function, and depressed mood and suicidal thoughts have also been reported.

Revia: Oral Naltrexone Brand

Revia is the primary brand name for oral naltrexone hydrochloride tablets in a 50 mg strength. Today, most prescriptions are filled with generic naltrexone, which is bioequivalent and significantly less expensive. The main advantage of oral naltrexone over injectable Vivitrol is lower cost and greater dosing flexibility, but it requires daily compliance, which patients in early recovery frequently struggle with.

Low Dose Naltrexone (LDN)

Low dose naltrexone (LDN) refers to naltrexone prescribed at doses ranging from 0.5 mg to 5 mg — a fraction of the standard 50 mg addiction treatment dose. LDN is used off-label and is not FDA-approved for any condition at these low doses. It is not a treatment for addiction and operates through a fundamentally different mechanism. The theory proposes that a brief, transient blockade of opioid receptors causes a rebound effect that increases the body's natural endorphin production. LDN has been investigated for conditions including fibromyalgia, multiple sclerosis, and Crohn's disease, but large-scale clinical trials are still needed.

Naltrexone Cost and Insurance

Generic oral naltrexone typically costs $30 to $80 per month without insurance. With insurance or discount programs, out-of-pocket cost can fall below $15. Vivitrol injections cost $1,000 to $1,800 without insurance, but most private plans, Medicaid, and Medicare cover it. Alkermes offers the Vivitrol Co-Pay Savings Program for insured patients and a Patient Assistance Program for those without insurance.

Naltrexone Dosage

The standard oral dose is 50 mg once daily, with some providers starting at 25 mg for the first day to minimize side effects. For Vivitrol, the dose is 380 mg as a single intramuscular injection every four weeks. Patients must be opioid-free for a minimum of 7 to 14 days before initiating either formulation.

Naltrexone vs Naloxone: What's the Difference?

Both are opioid antagonists, but they differ in duration and use. Naloxone (Narcan) is a short-acting emergency overdose reversal agent that takes effect within minutes and wears off in 30 to 90 minutes. Naltrexone is a long-acting antagonist for ongoing relapse prevention, providing blockade for 24 hours (oral) or 30 days (Vivitrol). Naloxone is also a component of Suboxone, where it deters injection misuse.

Naltrexone vs Suboxone

Suboxone contains buprenorphine (a partial opioid agonist) that mildly stimulates opioid receptors, reducing cravings and withdrawal. Naltrexone fully blocks receptors with zero agonist activity. Patients must be fully detoxed before starting naltrexone, whereas Suboxone can be initiated during early withdrawal. A landmark 2017 clinical trial (X:BOT) found that among patients who successfully started treatment, relapse rates were similar between Vivitrol and Suboxone.

Naltrexone and Weight Loss

Naltrexone is one of two active ingredients in Contrave (naltrexone/bupropion), an FDA-approved weight management medication. However, naltrexone alone is not approved for weight loss. Some patients undergoing addiction treatment report modest weight changes related to reduced alcohol calories or appetite-suppressing side effects, but naltrexone should not be selected as an addiction medication primarily for weight effects.

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Medically Reviewed Updated October 2026

Reviewed by licensed addiction specialists. Information reflects current clinical guidance.

Sources:SAMHSA·NIDA·CDC

Need immediate help? Call SAMHSA: 1-800-662-4357 (24/7, free)