Naltrexone and Vivitrol Treatment Centers
Naltrexone is an FDA-approved opioid antagonist medication used to treat both alcohol dependence and opioid use disorder. Available as a daily oral tablet (Revia) or a monthly Vivitrol injection, naltrexone works by blocking opioid receptors in the brain to reduce cravings and prevent relapse. Use our directory to find treatment centers that offer naltrexone-based medication-assisted treatment near you.
Found 7,994 treatment centers offering naltrexone (vivitrol) across the United States.
Need Help Finding the Right Treatment Center?
Speak with a compassionate specialist now - 100% free & confidential
Showing 14 of 7994 results

Zenith Behavioral Health, located in Phoenix, AZ, provides an extensive range of addiction treatment services catering to both adults and children. This center focuses on detoxification, addressing substance use issues, and treating co-occurring mental health conditions. With inpatient hospital programs available and round-the-clock care, Zenith Behavioral Health fosters a nurturing atmosphere conducive to recovery. The facility employs proven methods, including 12-step facilitation, anger management strategies, and brief interventions. Specialized programs are available for teenagers and those affected by trauma, addressing distinct needs. Zenith Behavioral Health offers exceptional care for both male and female clients pursuing sustainable recovery.

Nestled in Exeter, RI, Zinnia Exeter stands as a leading recovery facility, delivering a spectrum of tailored programs for those pursuing freedom from addiction. The facility offers hospital-based inpatient detox, round-the-clock hospital inpatient support, and extended residential care. Emphasizing 12-step integration, emotional regulation strategies, and concise intervention methods, Zinnia Exeter welcomes adult individuals, including those impacted by domestic or intimate partner abuse. This establishment is committed to providing excellent, all-encompassing treatment to aid adults and young adults of any gender in their path to lasting abstinence.

Situated in Glen Oaks, NY, Zucker Hillside Hospital Northwell provides dedicated rehabilitation services for adults dealing with substance use issues and serious co-occurring mental health disorders, as well as emotional challenges in children. The facility offers outpatient care options such as methadone/buprenorphine therapy and standard outpatient programs. With customized methods including 12-step programs, anger management, and brief therapeutic interventions, the center serves adult men and women, particularly those who have experienced intimate partner violence. Catering to individuals of all genders, this center emphasizes personalized care and utilizes evidence-based practices to foster sustainable recovery.

Situated in Birmingham, AL, Zukoski Outpatient delivers extensive treatment for substance use issues among both adults and young adults. This facility is dedicated to addressing co-occurring substance use disorders in conjunction with significant mental health conditions or emotional challenges. Emphasizing intensive outpatient programs and tailored support for trauma survivors, individuals with dual diagnoses, and those facing pain alongside substance use, the center adopts a customized strategy for rehabilitation. By implementing evidence-based practices like 12-step support, anger management, and brief intervention strategies, Zukoski Outpatient guarantees exceptional care for clients of all genders pursuing recovery.

Situated in Toledo, OH, Zepf Center delivers complete addiction recovery solutions for adults and young adults. This establishment offers detox and substance use treatment via intensive outpatient, outpatient, and day treatment options. Focusing on anger management, brief intervention, and cognitive behavioral therapy, Zepf Center serves both male and female individuals, including expectant/new mothers and those involved with the criminal justice system or forensic services. The center’s specific programs are designed to meet the distinct requirements of these groups. Individuals can anticipate high-standard care and customized recovery strategies to aid their healing process.

Situated in Las Cruces, NM, Zia Recovery Center delivers an array of all-inclusive addiction rehabilitation services. The facility encompasses detoxification, treatment for substance use disorders, transitional housing, and options for sober living, available in formats such as intensive outpatient care, long-term residential programs, and outpatient services. Zia Recovery Center employs methods including 12-step approaches, anger management techniques, and brief intervention strategies, serving adult men and women, as well as individuals who have faced domestic violence or intimate partner violence. With an emphasis on both adult and young adult populations, the center provides dedicated support specifically designed for males and females. Discover exceptional care and personalized assistance at Zia Recovery Center.

Residential detoxification and short and long-term residential treatment are available at iVital Wellness in Canyon Country, California, with buprenorphine and naltrexone used for opioid and alcohol use disorders. Programs address co-occurring mental health conditions, chronic pain, and trauma. Private insurance and self-pay are accepted, with Spanish and sign language services.

Residential treatment in New Harmony, Utah, is offered by Zion Recovery with short-term and long-term stays for adults with substance use and co-occurring serious mental illness. Buprenorphine and naltrexone are used in treatment. Medicaid, TRICARE, SAMHSA block grant funding, payment assistance, and a sliding fee scale are among the payment options.

Intensive and regular outpatient treatment with buprenorphine or naltrexone is combined with sober housing at Zysk Recovery Partners in Augusta, Maine. Programs serve veterans, pregnant and postpartum women, forensic clients, and trauma survivors. Medicaid, Medicare, and a sliding fee scale are available.

Youth and Shelter Services (YSS) in Webster City, IA, stands as a respected rehabilitation center. They offer outpatient services for individuals struggling with substance use, co-occurring mental health conditions, and emotional challenges in children. The center has tailored programs for active duty military personnel, teenagers, and adult men, serving both adult men and women, as well as seniors. Employing proven methods such as cognitive behavioral therapy and the Matrix Model, YSS delivers effective care through brief interventions. For those requiring medication-assisted treatment, they provide outpatient options including methadone/buprenorphine or naltrexone. YSS is dedicated to creating personalized recovery plans to assist each individual's healing process.

Situated in El Paso, TX, the Ysleta Del Sur Pueblo rehabilitation center provides outpatient services for those facing challenges related to substance abuse and concurrent mental health disorders. This establishment is dedicated to delivering focused support for adults experiencing emotional issues and for children with psychological conditions. Emphasizing techniques such as 12-step guidance, anger management strategies, and brief intervention, the center accommodates adult men, adult women, and teens. With programs customized for each gender, it ensures a well-rounded recovery experience. The center’s dedication to high-quality care and personalized treatment options makes it a leading choice for effective rehabilitation in the El Paso region.

Situated in Atlantic, IA, ZION Integrated Behav Health Services presents a wide array of treatment solutions for those facing challenges with substance use and concurrent mental health issues. This facility features intensive outpatient, outpatient, and standard outpatient programs that integrate multiple methodologies, including anger management, brief interventions, and cognitive behavioral therapy. ZION Integrated Behav Health Services is equipped with specialized programs tailored for adolescents, adult men, and adult women, addressing a broad spectrum of needs. Serving both adults and seniors of all genders, the center prioritizes personalized care and guidance to assist clients in attaining enduring recovery and enhanced mental health.

Zenith Hope Center LLC, located in Charlotte, NC, specializes in top-tier treatment for substance use disorders through its intensive outpatient, outpatient, and medication-assisted programs featuring methadone, buprenorphine, or naltrexone. Their therapeutic strategies encompass anger management, brief interventions, and cognitive behavioral therapy. The center specifically supports active duty military members and adult clients, including both men and women, with tailored programs to meet diverse needs. Zenith Hope Center LLC focuses on delivering holistic care for adults and young adults regardless of gender. With a strong emphasis on high-quality, evidence-based services within a nurturing atmosphere, this facility is an outstanding option for individuals seeking to overcome addiction.

Situated in Zuni, NM, Zuni Recovery Center delivers exceptional treatment for substance use through its outpatient and regular outpatient services. This facility is dedicated to managing anger, offering brief interventions, and employing cognitive behavioral therapy to provide customized care for those on their recovery journey. It features specialized programs catering to active duty military personnel, teens, and adult men, addressing a wide range of needs. The center supports a diverse clientele, including adults, children, and seniors, ensuring that all age groups receive thorough assistance. With an emphasis on both male and female patients, Zuni Recovery Center adopts a holistic methodology in rehabilitation, fostering sustained recovery and overall wellness.
Frequently Asked Questions
What is naltrexone and how does it work?
What are the most common naltrexone side effects?
What is Vivitrol and how is the injection administered?
What is the difference between naltrexone and naloxone?
How does naltrexone compare to Suboxone?
What is the standard naltrexone dosage?
How much does naltrexone cost and does insurance cover it?
What is low dose naltrexone (LDN)?
About Naltrexone (Vivitrol)
Naltrexone is an opioid antagonist, meaning it binds to the mu-opioid receptors in the brain without activating them. By occupying these receptors, naltrexone effectively blocks the rewarding effects of opioids and reduces the neurochemical reinforcement that drives alcohol cravings. Unlike medications such as methadone or buprenorphine, naltrexone has no potential for abuse or physical dependence because it produces no opioid effect whatsoever.
How Naltrexone Works
When a person taking naltrexone consumes alcohol, the pleasurable dopamine surge that normally reinforces drinking behavior is significantly blunted. For individuals with opioid dependence, naltrexone prevents any ingested opioid from reaching the receptors, rendering opioid use ineffective. This pharmacological mechanism makes naltrexone a cornerstone of medication-assisted treatment (MAT) programs across the country. Naltrexone was first approved by the FDA in 1984 for opioid dependence and received additional approval for alcohol dependence in 1994.
Naltrexone Side Effects
Common side effects include:
- Nausea, especially during the first few days
- Headache and dizziness
- Fatigue and insomnia
- Joint and muscle pain
- Decreased appetite and anxiety
Serious side effects are less common but include signs of liver injury such as yellowing of the skin or eyes, dark urine, and persistent abdominal pain. Severe injection site reactions from Vivitrol, including tissue necrosis, have been reported in rare cases. Importantly, naltrexone lowers opioid tolerance over time — if a person discontinues naltrexone and attempts to use opioids at previously tolerated doses, the risk of fatal overdose increases significantly.
Naltrexone for Alcohol Dependence
Naltrexone is one of only three FDA-approved medications for alcohol use disorder, alongside disulfiram (Antabuse) and acamprosate (Campral). For individuals struggling with alcohol dependence, naltrexone reduces heavy drinking days and increases the percentage of days abstinent. The oral formulation, sold under the brand name Revia, is typically prescribed at 50 mg daily and is most effective when combined with behavioral therapy and support groups.
Naltrexone for Opioid Dependence
For opioid dependence, naltrexone serves as a relapse-prevention tool rather than a detox medication. Patients must complete a full opioid detoxification and remain opioid-free for a minimum of 7 to 14 days before beginning naltrexone therapy. Starting naltrexone while opioids are still present can trigger sudden and severe precipitated withdrawal. Once initiated, naltrexone provides a pharmacological safety net — if a patient relapses, naltrexone blocks the drug from producing its usual effects.
Vivitrol: Injectable Naltrexone
Vivitrol is the brand name for naltrexone extended-release injectable suspension, delivering 380 mg in a single intramuscular dose once per month. A healthcare provider injects Vivitrol into the gluteal muscle using a special needle included in the product kit, alternating sides each month. The Vivitrol shot has become increasingly popular because it solves one of the biggest challenges in addiction treatment: medication adherence. Studies show that patients receiving monthly Vivitrol injections are significantly more likely to remain in treatment compared to those prescribed daily oral naltrexone.
Vivitrol Side Effects
Vivitrol shares many side effects with oral naltrexone but carries additional risks related to the injection site. These range from mild tenderness, redness, and swelling to severe complications including induration and in rare cases tissue necrosis requiring surgical intervention. As with oral naltrexone, Vivitrol can affect liver function, and depressed mood and suicidal thoughts have also been reported.
Revia: Oral Naltrexone Brand
Revia is the primary brand name for oral naltrexone hydrochloride tablets in a 50 mg strength. Today, most prescriptions are filled with generic naltrexone, which is bioequivalent and significantly less expensive. The main advantage of oral naltrexone over injectable Vivitrol is lower cost and greater dosing flexibility, but it requires daily compliance, which patients in early recovery frequently struggle with.
Low Dose Naltrexone (LDN)
Low dose naltrexone (LDN) refers to naltrexone prescribed at doses ranging from 0.5 mg to 5 mg — a fraction of the standard 50 mg addiction treatment dose. LDN is used off-label and is not FDA-approved for any condition at these low doses. It is not a treatment for addiction and operates through a fundamentally different mechanism. The theory proposes that a brief, transient blockade of opioid receptors causes a rebound effect that increases the body's natural endorphin production. LDN has been investigated for conditions including fibromyalgia, multiple sclerosis, and Crohn's disease, but large-scale clinical trials are still needed.
Naltrexone Cost and Insurance
Generic oral naltrexone typically costs $30 to $80 per month without insurance. With insurance or discount programs, out-of-pocket cost can fall below $15. Vivitrol injections cost $1,000 to $1,800 without insurance, but most private plans, Medicaid, and Medicare cover it. Alkermes offers the Vivitrol Co-Pay Savings Program for insured patients and a Patient Assistance Program for those without insurance.
Naltrexone Dosage
The standard oral dose is 50 mg once daily, with some providers starting at 25 mg for the first day to minimize side effects. For Vivitrol, the dose is 380 mg as a single intramuscular injection every four weeks. Patients must be opioid-free for a minimum of 7 to 14 days before initiating either formulation.
Naltrexone vs Naloxone: What's the Difference?
Both are opioid antagonists, but they differ in duration and use. Naloxone (Narcan) is a short-acting emergency overdose reversal agent that takes effect within minutes and wears off in 30 to 90 minutes. Naltrexone is a long-acting antagonist for ongoing relapse prevention, providing blockade for 24 hours (oral) or 30 days (Vivitrol). Naloxone is also a component of Suboxone, where it deters injection misuse.
Naltrexone vs Suboxone
Suboxone contains buprenorphine (a partial opioid agonist) that mildly stimulates opioid receptors, reducing cravings and withdrawal. Naltrexone fully blocks receptors with zero agonist activity. Patients must be fully detoxed before starting naltrexone, whereas Suboxone can be initiated during early withdrawal. A landmark 2017 clinical trial (X:BOT) found that among patients who successfully started treatment, relapse rates were similar between Vivitrol and Suboxone.
Naltrexone and Weight Loss
Naltrexone is one of two active ingredients in Contrave (naltrexone/bupropion), an FDA-approved weight management medication. However, naltrexone alone is not approved for weight loss. Some patients undergoing addiction treatment report modest weight changes related to reduced alcohol calories or appetite-suppressing side effects, but naltrexone should not be selected as an addiction medication primarily for weight effects.
Naltrexone resources:
Related Treatment Methods
Browse by Condition
Browse naltrexone (vivitrol) programs in states with the most treatment options.
Related conditions, treatment approaches, and levels of care.
Need immediate help? Call SAMHSA: 1-800-662-4357 (24/7, free)