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Medically Reviewed Content
Updated: September 2026
Sources: SAMHSA, NIDA

Depression & Addiction Treatment Centers Near You

Depression and addiction frequently co-occur, requiring integrated treatment approaches. Find dual diagnosis treatment centers addressing both mental health and substance use disorders through coordinated care and evidence-based therapies.

Found 7,770 rehab centers specializing in depression across the United States.

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Find Depression and Addiction Treatment Centers Near You

Browse dual diagnosis treatment centers below. Filter for programs treating depression and substance abuse together.

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Emergence
Cottage Grove, OR

Emergence, situated in Cottage Grove, OR, stands out as a prominent outpatient rehabilitation facility dedicated to assisting adults and young adults dealing with substance use challenges. The center employs proven treatment strategies, including cognitive behavioral therapy, motivational interviewing, and relapse prevention techniques. A distinctive feature of Emergence is its targeted programs for individuals who have faced trauma, those dealing with both mental health and substance use issues, as well as patients suffering from simultaneous pain and substance use disorders. Committed to personalized care, the center crafts individualized treatment plans for both men and women, fostering a thorough and supportive path to recovery.

Emerson Hospital
Concord, MA

Situated in Concord, MA, Emerson Hospital provides extensive treatment options for individuals dealing with substance use issues, catering to both adults and young adults. This center is adept at addressing co-occurring substance use disorders alongside serious mental health challenges in adults, in addition to significant emotional issues in children. Offering a variety of programs such as intensive outpatient treatment, outpatient services, and day treatment, Emerson Hospital emphasizes methods like 12-step facilitation, cognitive behavioral therapy, and motivational interviewing. They deliver customized care for adult men and women, including those with co-occurring conditions. By offering gender-specific programs, Emerson Hospital fosters a nurturing atmosphere for all clients. Opt for Emerson Hospital for exceptional care and targeted treatment methodologies.

Empowerment Center

Situated in Reno, NV, the Empowerment Center is dedicated to providing targeted substance use treatment for adult women within a nurturing and secure setting. This facility features intensive outpatient services, as well as outpatient options for methadone/buprenorphine and naltrexone therapies. Emphasizing methods such as 12-step guidance, anger management, and cognitive behavioral therapy, the program is designed for those who have encountered issues like intimate partner violence, domestic violence, or sexual assault. Catering to a diverse range of clients, including adults, seniors, and young adults, this center is committed to supporting women in their recovery journeys through comprehensive care and personalized assistance.

Empowerment Resource Center Inc

Empowerment Resource Center Inc. in Atlanta, GA, offers thorough addiction care for adults and adolescents facing concurrent severe mental health conditions. They provide intensive outpatient, outpatient, and standard outpatient services, employing scientifically validated methods like cognitive behavioral therapy, motivational interviewing, and strategies to prevent relapse. The center is particularly experienced in assisting active duty military members, adult men, and adult women, serving both male and female individuals. Committed to high-quality support and personalized treatment plans, Empowerment Resource Center Inc. aims to equip clients for a successful recovery path.

Empowerment Program

The Empowerment Program, situated in Denver, CO, delivers targeted recovery support for adults and adolescents facing substance abuse and concurrent severe mental health challenges. They offer a range of treatment intensities including intensive outpatient, outpatient, and standard outpatient options. Their therapeutic approaches emphasize anger management, brief interventions, and cognitive behavioral techniques, serving both adult men and women, and individuals affected by intimate partner or domestic abuse. The program is customized to address the distinct requirements of each person, guaranteeing effective care for everyone on their journey to wellness.

Empower Recovery Services

Empower Recovery Services in Pine City, MN, delivers a complete spectrum of substance abuse therapies for adults and young adults dealing with co-occurring severe mental health conditions. This institution features intensive outpatient, standard outpatient, and regular outpatient tracks, customized for each person's unique requirements. Employing methods like 12-step facilitation, anger management, and brief intervention strategies, the facility champions a well-rounded path to healing. Its specialized offerings for active duty military members, adult men, and women demonstrate a commitment to serving varied populations. Providing effective care to all genders, Empower Recovery Services distinguishes itself as a nurturing and successful recovery destination for those navigating addiction and mental health struggles.

Empowered for Excellence

"Empowered for Excellence" located in Toledo, OH, delivers tailored substance use rehabilitation services for adults and seniors in an outpatient format. This center features intensive outpatient treatment, standard outpatient care, and partial hospitalization options. Emphasizing 12-step facilitation, anger management, and brief intervention techniques, the center serves both male and female clients. It also offers distinct programs specifically designed for adolescents, as well as adult men and women. With a dedication to high-quality care and personalized treatment plans, the center stands out as a significant asset for individuals pursuing addiction recovery in the Toledo region.

Empowering Mindz
Catonsville, MD

Empowering Mindz, situated in Catonsville, MD, provides extensive treatment options for substance use tailored for both adults and seniors. The center offers a range of services, including intensive outpatient, outpatient, and standard outpatient programs, all rooted in evidence-based methods such as brief intervention, cognitive behavioral therapy, and the Matrix Model. With programs designed specifically for active duty service members, teenagers, and adult males, in addition to customized services for both genders, this facility emphasizes personalized care. Empowering Mindz is committed to fostering long-term recovery, supported by a devoted team of professionals who deliver exceptional care and assistance.

Emergence
Eugene, OR

Emergence, situated in Eugene, Oregon, provides extensive treatment for substance use disorders and addresses co-occurring severe mental health issues in adults, as well as significant emotional challenges in children. The center offers various treatment modalities such as intensive outpatient, outpatient, and standard outpatient programs. Care is personalized through techniques including anger management, cognitive behavioral therapy, and community reinforcement with incentives. Specialized programs are tailored for active duty military personnel, adult men, and women, meeting diverse requirements. Welcoming individuals of all genders, Emergence is dedicated to delivering high-quality rehabilitation and support for those in need of effective recovery solutions.

Emergence
Eugene, OR

Emergence, situated in Eugene, OR, specializes in treating substance use issues among adults and young adults. The center features a variety of outpatient services, which encompass intensive outpatient programs, standard outpatient care, and personalized treatment plans. By employing evidence-based techniques such as cognitive behavioral therapy, the Matrix Model, and motivational interviewing, Emergence customizes its approach to align with the distinct requirements of each client. The facility includes specialized programs for adult men and women, as well as those who have endured trauma, fostering a compassionate and inclusive atmosphere. By offering support to both genders, this center emphasizes comprehensive care and holistic recovery for those battling substance use disorders.

Emergence
Florence, OR

Nestled in Florence, OR, Emergence stands as a premier addiction treatment facility. They provide comprehensive care through intensive outpatient, outpatient, and standard outpatient services. Their treatment modalities are rooted in proven methods including cognitive behavioral therapy, the Matrix Model, and motivational interviewing. A key differentiator for Emergence is their dedicated programs for individuals with histories of trauma, those managing co-occurring mental health and substance use conditions, and people navigating chronic pain alongside addiction. Serving adults and young adults across the gender spectrum, Emergence is committed to delivering personalized, top-tier support.

Employee Assistance Resource Servs Inc

Employee Assistance Resource Servs Inc in Smithtown, NY, provides an extensive variety of rehabilitation services aimed at adults and younger individuals dealing with substance use issues and related mental health disorders. This facility features intensive outpatient care, regular outpatient programs, and detoxification services on an outpatient basis. With tailored programs for active military members, as well as specific services for adult men and women, it addresses a wide array of needs. Treatment methods include cognitive behavioral therapy, anger management, and motivational incentives, guaranteeing a comprehensive and personalized approach to recovery. Committed to delivering high-quality care and customized treatment plans, this center stands as a source of hope for individuals striving for enduring sobriety.

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Eugene, OR

In Eugene, Oregon, Emergence stands as a complete treatment facility dedicated to aiding adults and young adults in overcoming substance abuse. They provide a range of services including intensive outpatient, outpatient, and standard outpatient care. Their therapeutic methods emphasize cognitive behavioral therapy, contingency management with motivational incentives, and motivational interviewing. Emergence offers tailored support for adult men, adult women, and individuals who have gone through trauma, addressing a variety of specific requirements. By adopting gender-specific approaches for both men and women, the center guarantees personalized care. Clients can anticipate receiving top-tier treatment within a nurturing setting aimed at fostering lasting recovery and enhanced health.

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Springfield, OR

Emergence, situated in Springfield, OR, is a specialized outpatient center dedicated to addressing substance use challenges. The program utilizes proven therapeutic methods, including cognitive behavioral therapy, the Matrix Model, and motivational interviewing, to guide individuals toward recovery. Distinctive services are available for those impacted by trauma, individuals managing co-occurring mental health and substance use conditions, and persons experiencing the intersection of pain and addiction. Catering to adults and young adults across all genders, Emergence fosters a nurturing setting for thorough care. Emphasizing excellence and personalized treatment plans, the center is committed to supporting clients in their journey to sustained well-being.

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Albany, OR

"Emergence," situated in Albany, OR, delivers thorough substance abuse recovery services for adults and younger adults. The facility features intensive outpatient, standard outpatient, and regular outpatient treatment tracks. Employing proven methods such as cognitive behavioral therapy, the Matrix Model, and motivational interviewing, this center customizes care to individual requirements. "Emergence" offers specialized programs for adult males, adult females, and individuals with trauma histories. Committed to high-quality assistance, the center serves both male and female patients, fostering a welcoming and inclusive setting for anyone pursuing freedom from substance use disorders.

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Emergence Health Network in El Paso, TX, provides targeted interventions for individuals grappling with addiction and concurrent significant mental health challenges. Their programs include intensive outpatient, outpatient, and day treatment, employing strategies like anger management, cognitive behavioral therapy, and brief interventions. Catering to active duty military, adult men, and women, the facility extends comprehensive assistance to adults and young adults across all gender identities. Their dedication to high-standard care and personalized recovery paths establishes them as a crucial provider of effective rehabilitation services within the El Paso community.

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Emmanuel House Inc in Detroit, MI, offers extensive programs for men struggling with substance use disorders and provides transitional living accommodations. Their services include inpatient hospital care and long-term residential stays, utilizing therapeutic methods such as 12-step facilitation, anger management, and brief interventions. With a focus on supporting individuals with histories of sexual abuse or trauma, Emmanuel House Inc serves adult men of all ages, including seniors and young adults. The center is committed to delivering excellent care and assistance within a secure and organized setting, positioning it as a premier destination for those pursuing recovery and healing from addiction.

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Situated in Emmett, ID, Emmett Family Services is a full-service rehabilitation center that provides intensive outpatient programs, standard outpatient treatments, and 12-step support for individuals dealing with substance use challenges. The center focuses on addressing co-occurring substance use and severe mental health conditions in adults, along with emotional issues in children. It offers customized programs aimed at active duty military personnel, teens, and adult males, ensuring gender-specific treatment for both men and women. By incorporating methods such as anger management and brief interventions, Emmett Family Services aims to offer personalized, high-quality care to adults and youth on their recovery journey from addiction.

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Empowerment Centre LLC in Las Vegas, NV, is a rehabilitation facility specializing in outpatient care for adults experiencing substance use disorders alongside mental health challenges. They offer targeted support for those with significant emotional disturbances. Through proven methods such as 12-step integration and anger management techniques, the program is tailored to meet the specific requirements of active military members, young people, and adult men. The center emphasizes personalized treatment strategies and accommodates both male and female clients of various ages. For those desiring thorough treatment within a nurturing setting, Empowerment Centre LLC is committed to guiding you toward lasting recovery.

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Encompass Community Center, situated in Watsonville, CA, specializes in long-term residential care for adults dealing with substance abuse and concurrent mental health challenges. The center emphasizes key therapeutic techniques such as anger management, cognitive behavioral therapy, and short-term interventions, offering customized support for men grappling with trauma and dual diagnoses. Catering to a diverse demographic that includes adults, seniors, and young adults, this facility provides around-the-clock residential assistance. By adopting a male-focused approach, Encompass Community Center guarantees personalized care and uses evidence-based practices to foster sustainable recovery. The center is committed to delivering high-quality support to empower clients in their journey towards complete healing and enduring sobriety.

Depression & Substance Use Disorder: Key Facts

Classification

Major Depressive Disorder + Substance Use Disorder (Dual Diagnosis)

Co-occurrence

~1 in 3 people with depression also have SUD (NIDA)

Prevalence

21 million adults with major depressive episode/year (NIMH)

Self-medication

Depression is the #1 reason for substance self-medication

Treatment approach

Integrated dual diagnosis (treat both simultaneously)

Key therapies

CBT, DBT, medication management, group therapy

Medications

SSRIs (non-addictive), SNRIs — safe during addiction treatment

Prognosis

Significantly better outcomes with integrated treatment vs sequential

If you or someone you know is experiencing suicidal thoughts, call 988 (Suicide & Crisis Lifeline) or text 988 immediately. Help is available 24/7.

Depression and Addiction: The Dual Diagnosis Connection

How depression and addiction feed each other

Depression and substance use disorder share a deeply intertwined relationship. Depression causes persistent feelings of emptiness, hopelessness, and emotional pain that drive many people toward alcohol or drugs as a form of self-medication. Substances may provide temporary relief, but they alter brain chemistry in ways that worsen depressive symptoms over time — creating a destructive cycle that accelerates both conditions.

The self-medication cycle

The self-medication cycle is the most common pathway from depression to addiction. A person experiencing persistent sadness, fatigue, or emotional numbness turns to alcohol, opioids, or stimulants to feel better temporarily. As tolerance builds, they need more of the substance to achieve the same relief. Meanwhile, the substance disrupts serotonin and dopamine regulation in the brain, deepening the depression. When the substance wears off, the depression returns worse than before — driving further substance use.

Why treating one without the other fails

Treating addiction without addressing underlying depression leaves the root cause intact. The person achieves sobriety but continues suffering from untreated depression, making relapse nearly inevitable as they seek relief. Conversely, treating depression without addressing active substance use is ineffective because ongoing drug or alcohol use undermines the neurochemical changes that antidepressants and therapy work to achieve. This is why dual diagnosis treatment — addressing both conditions simultaneously — produces significantly better outcomes than treating either condition alone.

Signs of Co-Occurring Depression and Substance Abuse

Recognizing co-occurring depression and substance abuse can be challenging because symptoms overlap. Watch for these warning signs:

Emotional and behavioral signs

  • Persistent sadness combined with increased substance use
  • Withdrawal from friends, family, and activities once enjoyed
  • Using drugs or alcohol specifically to cope with emptiness or hopelessness
  • Feelings of worthlessness or excessive guilt alongside substance use
  • Loss of motivation or interest in recovery efforts

Physical signs

  • Significant changes in sleep patterns — insomnia or oversleeping
  • Appetite and weight changes (loss or gain)
  • Chronic fatigue even with adequate rest
  • Increased substance tolerance requiring higher doses
  • Neglect of personal hygiene and self-care

How Dual Diagnosis Treatment Works

Integrated approach

Dual diagnosis treatment treats depression and addiction as interconnected conditions rather than separate problems. Instead of completing addiction treatment first and then addressing depression (the sequential approach that often fails), integrated programs work on both simultaneously. This means therapy sessions address how depressive thoughts drive substance use, while psychiatric care stabilizes mood to support sobriety.

Psychiatric evaluation during early sobriety

Accurate diagnosis of depression requires evaluation during a period of sobriety, because many substances can mimic or mask depressive symptoms. Alcohol is a depressant that causes sadness and lethargy. Stimulant withdrawal causes profound depression. A psychiatrist experienced in dual diagnosis will conduct thorough assessments during early sobriety to distinguish substance-induced mood changes from underlying major depressive disorder, ensuring the right treatment plan.

Coordinated care teams

Effective dual diagnosis programs use coordinated care teams where psychiatrists, addiction counselors, therapists, and medical staff communicate about each patient's progress. The psychiatrist managing antidepressant medication works closely with the addiction counselor guiding recovery, so treatment decisions account for both conditions. This prevents the common problem of one provider unknowingly undermining another's treatment plan.

Medication management alongside addiction treatment

One of the most important aspects of dual diagnosis care is safe medication management. Antidepressants like SSRIs and SNRIs are non-addictive and can be prescribed safely during addiction treatment. A psychiatrist monitors medication effectiveness, adjusts dosages, and watches for interactions — all while the person is actively working on recovery from substance use disorder.

Evidence-Based Therapies for Depression in Recovery

Cognitive Behavioral Therapy (CBT)

Cognitive Behavioral Therapy (CBT) is the gold standard for treating co-occurring depression and addiction. CBT helps identify negative thought patterns that drive both depressive episodes and substance use — such as "nothing will ever get better" or "I can't cope without drinking." Patients learn to challenge these distortions and replace them with realistic, constructive thinking. Research consistently shows CBT reduces both depressive symptoms and substance use relapse rates.

Dialectical Behavior Therapy (DBT)

Dialectical Behavior Therapy (DBT) is particularly effective for people with severe depression, emotional dysregulation, or self-harm behaviors alongside addiction. DBT teaches four core skill sets: mindfulness, distress tolerance, emotion regulation, and interpersonal effectiveness. These skills directly address the emotional pain that drives self-medication and provide healthier alternatives to substance use.

Group therapy

Group therapy combats the isolation that is central to both depression and addiction. Hearing others share similar struggles reduces shame and hopelessness. Dual diagnosis groups specifically address how depression and substance use interact, offering peer support from people who understand both conditions. Group settings also build social skills and accountability that support long-term recovery.

Medication management

Antidepressant medications are a critical component of treatment for many people with co-occurring depression and addiction. SSRIs (selective serotonin reuptake inhibitors) like sertraline and fluoxetine are first-line treatments because they are effective, well-tolerated, and — importantly — non-addictive. They carry no abuse potential and do not produce euphoria, making them safe to prescribe during addiction recovery. SNRIs like venlafaxine and duloxetine are also effective alternatives.

Levels of Care for Depression and Addiction

When residential treatment is needed

Residential treatment is recommended when depression is severe — particularly when suicidal ideation is present, when the person has made previous suicide attempts, or when outpatient treatment has failed. Residential programs provide 24/7 psychiatric monitoring, immediate medication adjustments, and a safe environment removed from triggers. People with severe addiction alongside major depression often need this level of structured support to stabilize both conditions.

Intensive Outpatient Programs (IOP)

Intensive Outpatient Programs provide 9–20 hours of structured therapy per week while allowing patients to live at home. IOP is appropriate for moderate depression with addiction, for people stepping down from residential care, or when the person has a stable living environment and support system. Dual diagnosis IOP programs include both addiction counseling and psychiatric services.

Outpatient care with medication management

Standard outpatient treatment works well for mild to moderate depression with substance use disorder, especially when combined with antidepressant medication. This typically involves weekly therapy sessions, regular psychiatric check-ins for medication management, and support group participation. Outpatient care allows people to maintain work, family, and daily responsibilities while receiving treatment.

Choosing the right level of care

The appropriate level of care depends on several factors: severity of depression (mild vs. severe with suicidal thoughts), severity of addiction, previous treatment attempts and outcomes, strength of social support, co-occurring medical conditions, and safety concerns. A professional assessment by a dual diagnosis specialist can determine the best starting point. Many people move through multiple levels of care as they progress in recovery.

Antidepressant Medications in Recovery

SSRIs: the first-line treatment

Selective serotonin reuptake inhibitors (SSRIs) such as sertraline (Zoloft), fluoxetine (Prozac), and escitalopram (Lexapro) are the most commonly prescribed antidepressants for people in addiction recovery. They work by increasing serotonin availability in the brain, gradually improving mood, sleep, and motivation over 4–6 weeks. SSRIs are not addictive, do not produce a high, and have no abuse potential — making them fundamentally different from the substances being treated.

SNRIs and bupropion

Serotonin-norepinephrine reuptake inhibitors (SNRIs) like venlafaxine (Effexor) and duloxetine (Cymbalta) target both serotonin and norepinephrine, which can be helpful for depression with prominent fatigue or chronic pain. Bupropion (Wellbutrin) is another option that acts on dopamine and norepinephrine — it can help with depression, low energy, and is also used to support smoking cessation. None of these medications carry addiction risk.

Addressing the stigma around psychiatric medication

Many people in recovery resist antidepressants because they feel taking any medication contradicts sobriety. This misconception is dangerous. Antidepressants are not mood-altering substances in the way drugs of abuse are — they restore normal brain chemistry rather than creating artificial highs. Untreated depression is one of the strongest predictors of addiction relapse. Taking prescribed, non-addictive medication to manage a medical condition is not a failure of recovery — it supports it.

Why stopping psychiatric meds leads to relapse

A common and harmful pattern occurs when people in recovery stop their antidepressants because they feel better, believe they no longer need them, or face pressure from others to be "medication-free." When depression returns — often within weeks — the emotional pain drives them back to substances. Antidepressant treatment for co-occurring depression should be maintained for at least 12 months after stabilization, and many people benefit from long-term maintenance. Any changes to psychiatric medication should be made gradually under medical supervision.

Frequently Asked Questions About Depression and Addiction

What is dual diagnosis treatment for depression and addiction?

Dual diagnosis treatment addresses both depression and substance use disorders simultaneously through integrated care. This approach recognizes that mental health and addiction affect each other and must be treated together for lasting recovery. Treatment includes psychiatric care, medication management, therapy (CBT, DBT), and specialized counseling that addresses both conditions comprehensively.

Can depression cause substance abuse?

Yes, depression significantly increases the risk of substance abuse. Many people self-medicate depression symptoms with alcohol or drugs, seeking temporary relief from emotional pain, low energy, or insomnia. However, substance use worsens depression long-term by disrupting serotonin and dopamine regulation, creating a vicious cycle. Proper treatment addresses root causes of depression while providing healthier coping strategies than substances.

Will antidepressants interfere with addiction treatment?

No, appropriate antidepressant medication actively supports recovery. Quality dual diagnosis programs work with psychiatrists to find effective antidepressant treatment while addressing addiction. Medications like SSRIs and SNRIs are non-addictive and help stabilize mood, making it easier to engage in therapy and maintain sobriety. Never stop psychiatric medications without medical guidance.

How do I find a treatment center for depression and addiction?

Look for centers explicitly offering dual diagnosis or co-occurring disorder treatment. Verify they have licensed mental health professionals, psychiatric services, medication management capabilities, and experience treating both conditions together. Use our directory to filter for dual diagnosis programs, read reviews, and verify accreditation. Contact admissions teams to discuss your specific needs.

Is residential treatment necessary for depression and addiction?

Not always. Treatment level depends on severity of both conditions, previous treatment attempts, safety concerns, and support system. Some people do well with intensive outpatient care plus medication management. Residential treatment provides 24/7 support for severe depression, suicide risk, or when outpatient treatment hasn't succeeded. A professional assessment determines the most appropriate level of care.

Can addiction cause depression or does depression cause addiction?

The relationship is bidirectional — it works both ways. Depression can lead to substance abuse through self-medication, as people use drugs or alcohol to escape emotional pain. At the same time, chronic substance use alters brain chemistry in ways that cause or worsen depression — alcohol is a central nervous system depressant, stimulant withdrawal causes profound depression, and opioid use disrupts the brain's natural mood regulation. In many cases, both conditions develop and reinforce each other simultaneously, which is why integrated dual diagnosis treatment is essential for lasting recovery.

Will I need antidepressants forever?

Not necessarily. Many people take antidepressants for 12–24 months after their mood stabilizes, then gradually taper off under medical supervision. However, some people with recurrent major depression (three or more episodes) benefit from long-term maintenance medication. The decision depends on depression severity, number of past episodes, family history, and individual response to treatment. What is critical is never stopping antidepressants abruptly — doing so can cause withdrawal symptoms and trigger relapse in both depression and addiction. Always work with your prescribing psychiatrist to make any medication changes.

Medical Review and Sources

Medically Reviewed Updated April 10, 2026

Reviewed by licensed addiction specialists. Information reflects current clinical guidance.

Sources:SAMHSA·NIDA·CDC

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