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Medically Reviewed Content
Updated: August 2026
Sources: SAMHSA, NIDA

Depression & Addiction Treatment Centers Near You

Depression and addiction frequently co-occur, requiring integrated treatment approaches. Find dual diagnosis treatment centers addressing both mental health and substance use disorders through coordinated care and evidence-based therapies.

Found 7,770 rehab centers specializing in depression across the United States.

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Find Depression and Addiction Treatment Centers Near You

Browse dual diagnosis treatment centers below. Filter for programs treating depression and substance abuse together.

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La Fuente Hollywood Treatment Ctr LLC

La Fuente Hollywood Treatment Ctr LLC in Los Angeles, California, provides extensive care for individuals struggling with addiction. Their offerings include detox services, comprehensive substance use disorder treatment, and secure transitional and sober living environments for adults. The center supports adults and young adults through various treatment modalities, such as intensive outpatient, extended residential stays, and standard outpatient care. They also have specialized support for active-duty military members. La Fuente Hollywood Treatment Ctr LLC employs proven therapeutic methods, including 12-step facilitation, anger management techniques, and brief intervention strategies, ensuring personalized and effective recovery plans.

La Hacienda Treatment Center

Situated in Hunt, TX, La Hacienda Treatment Center delivers extensive addiction recovery programs for both adults and young individuals. This facility features hospital-level inpatient detox and treatment, focusing on co-existing substance use disorders alongside severe mental health issues in adults, and addressing significant emotional challenges in children. La Hacienda Treatment Center employs evidence-supported methodologies like 12-step facilitation, cognitive behavioral therapy, and strategies for preventing relapse. With programs designed specifically for adult men, adult women, and those who have faced trauma, this center guarantees personalized attention for every patient. By prioritizing gender-specific care for males and females alike, La Hacienda Treatment Center is committed to offering superior and effective rehabilitation solutions.

La Jolla Recovery
La Jolla, CA

Situated in La Jolla, CA, La Jolla Recovery delivers dedicated treatment for adults and seniors dealing with substance use issues. The facility features a variety of services, including intensive outpatient programs, standard outpatient care, and partial hospitalization options. With an emphasis on 12-step methods, anger management, and brief intervention strategies, this center serves both men and women, including those who have faced trauma. La Jolla Recovery prioritizes personalized care for its clients, focusing on high-quality treatment in a nurturing setting for individuals pursuing thorough addiction recovery.

La Jolla Recovery
La Jolla, CA

Situated in La Jolla, California, La Jolla Recovery stands out as a leading rehabilitation facility dedicated to assisting those facing challenges with substance use and related mental health issues. This center provides an array of services, including long-term residential treatment options, detoxification programs, and round-the-clock support for both adults and seniors. La Jolla Recovery emphasizes personalized care through methods such as 12-step guidance, anger management, and brief intervention techniques. Catering to adult men, adult women, and those with co-occurring conditions, this center is committed to fostering a nurturing recovery atmosphere. Whether you are in need of detox or extended therapeutic support, the facility is focused on providing exceptional care for individuals on their path to sustained recovery.

La Jolla Recovery
San Diego, CA

La Jolla Recovery, situated in San Diego, CA, provides extensive programs for addiction recovery and detox within a nurturing setting. The center features extended residential stays, immediate detoxification services, and constant residential support. Employing methods like 12-step guidance, emotional regulation techniques, and focused interventions, this establishment assists adult men and women, including those who have faced traumatic experiences. Catering to adults and older adults of all genders, La Jolla Recovery is committed to personalized treatment plans and tailored programs to guide each person through their recovery journey.

LA Valley Recovery
North Hollywood, CA

LA Valley Recovery, located in North Hollywood, CA, provides extensive treatment for addiction, designed for those aiming for a sober life. This establishment features inpatient hospital detox and treatment options for adults and younger adults. Recognizing the diverse needs of its clients, LA Valley Recovery has distinct programs for active military members, adult men, and adult women, fostering a welcoming atmosphere for everyone. The center employs scientifically proven methods, including 12-step support, emotional regulation techniques, and concise counseling strategies, to combat substance abuse issues. Individuals undergoing treatment can anticipate exceptional medical attention and customized recovery roadmaps to aid their pursuit of lasting sobriety.

Labette Center for MH Services Inc

Labette Center for MH Services Inc, located in Parsons, KS, is dedicated to providing specialized recovery programs for adults and older adults struggling with addiction and co-occurring mental health conditions. They offer comprehensive intensive outpatient and outpatient services, which may include medication-assisted treatment such as methadone, buprenorphine, or naltrexone. The center employs therapeutic strategies like cognitive behavioral therapy, anger management techniques, and brief intervention methods. Their services are designed to support individuals with a history of trauma and those navigating the legal system. Labette Center ensures individualized care plans for both men and women, fostering a secure and welcoming atmosphere for all individuals on their journey to wellness.

Laguna Shores Behavioral Health LLC

Laguna Shores Behavioral Health LLC, situated in Dana Point, CA, provides extensive recovery programs. Their focus includes detox, addiction treatment, and dual diagnosis care for adults, as well as emotional health support for children. The center offers inpatient hospital detox and treatment, incorporating methods like 12-step support, brief counseling, and cognitive behavioral therapy. Specialized tracks are designed for adult men and women, those affected by intimate partner violence, and survivors of domestic abuse. Catering to adults and young adults across the gender spectrum, Laguna Shores Behavioral Health LLC delivers exceptional care within a nurturing atmosphere.

Laguna View Detox
Laguna Beach, CA

Nestled in the scenic surroundings of Laguna Beach, CA, Laguna View Detox provides an extensive array of services aimed at treating addiction. This center focuses on detoxification, treatment for substance use, and support for individuals battling co-occurring mental health issues, accommodating both adults and children. With options for residential detox and short-term residential stays, the facility ensures round-the-clock assistance, employing methods such as 12-step facilitation and anger management therapy. Specialized programs are available for active-duty military members as well as adult men and women, addressing the needs of both adult and young adult clients. Laguna View Detox is dedicated to offering exceptional care in a tranquil coastal environment.

Lafayette Medical Approach LLC

Situated in New York, NY, Lafayette Medical Approach LLC specializes in outpatient detoxification and treatment for substance use disorders in adult men and women. The center employs various evidence-based strategies, such as brief interventions, cognitive behavioral therapy, and contingency management with motivational incentives. It also features specialized programs for individuals who have undergone trauma, concentrating on both adults and young adults. With a gender-specific focus for males and females, the facility is committed to offering personalized care for every client. Lafayette Medical Approach LLC strives to deliver exceptional, all-encompassing rehabilitation services to assist clients throughout their recovery process.

Labyrinth Assessment/Behavioral Servs

Situated in Malad City, ID, Labyrinth Assessment/Behavioral Servs is a well-respected rehabilitation facility that provides outpatient treatment for substance use and offers specialized services for individuals dealing with both substance use and significant mental health challenges. The center employs evidence-based methodologies, including 12-step support, anger management, and cognitive behavioral therapy. Committed to personalized care, the center presents distinct programs designed for adolescents as well as adult men and women. Catering to adults and seniors of all genders, Labyrinth Assessment/Behavioral Servs is focused on providing exceptional, customized treatment to promote enduring recovery.

LAGS Recovery Centers Inc

In Santa Maria, CA, LAGS Recovery Centers Inc delivers focused care for adults and young adults grappling with co-occurring serious mental health conditions or emotional difficulties. The center provides comprehensive treatment including intensive outpatient, outpatient, and medication-assisted options such as methadone, buprenorphine, and naltrexone. Utilizing personalized strategies like 12-step facilitation, anger management techniques, and brief intervention methods, LAGS Recovery Centers Inc serves adult men and women, accommodating those who have endured intimate partner violence. The facility is equipped to assist both male and female individuals, dedicating itself to offering superior support throughout their recovery path.

La Familia Counseling Service

Situated in Oakland, CA, La Familia Counseling Service delivers outpatient treatment for substance use and co-occurring disorders for both adults and youth. The center utilizes evidence-based methods in its regular outpatient programs, including anger management, brief intervention, and cognitive behavioral therapy. It focuses on unique programs designed for adolescents as well as those impacted by intimate partner violence, domestic abuse, and sexual trauma. La Familia Counseling Service offers personalized care aimed at addressing diverse mental health requirements, fostering a supportive and empathetic atmosphere for individuals of all ages and genders.

La Jolla Healing Center

Nestled in La Jolla, California, La Jolla Healing Center provides extensive recovery support for adults and young adults facing addiction and intertwined mental health challenges. This establishment features intensive outpatient, day treatment, and partial hospitalization options. Emphasizing 12-step principles, emotional regulation, and concise therapeutic strategies, the center addresses the specific requirements of active military members, adult men, and adult women. Through tailored programs and gender-conscious support, La Jolla Healing Center delivers personalized care pathways aimed at sustained wellness and complete recovery.

La Trenza Counseling Inc
Commerce City, CO

Located in Commerce City, CO, La Trenza Counseling Inc offers comprehensive substance use treatment for adults and young adults dealing with co-occurring mental health issues. The center provides intensive outpatient, outpatient, and regular outpatient treatment using evidence-based approaches such as 12-step facilitation, anger management, and brief intervention. With specialized programs for active duty military, adult men, and adult women, La Trenza Counseling Inc caters to diverse populations. Their tailored care for both male and female clients ensures a supportive and inclusive environment for all individuals seeking recovery.

Lafayette Behavioral Health Unit

Nestled in Lafayette, LA, Lafayette Behavioral Health Unit delivers thorough recovery programs for adults and young adults navigating addiction, co-occurring mental health challenges, and trauma. Prioritizing excellent support, the center offers inpatient hospital detoxification and care, featuring tailored plans for those with intricate requirements. Lafayette Behavioral Health Unit distinguishes itself with virtual therapy services, serving both male and female patients. Whether it's tackling substance dependency, mental wellness concerns, or a combination of both, this establishment is committed to aiding individuals in their path to healing.

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La Frontera Center, situated in Tucson, Arizona, delivers extensive treatment for substance use and expert care for those facing serious co-occurring mental health issues. The center features intensive outpatient programs and offers both outpatient services and treatment options such as methadone, buprenorphine, or naltrexone. Emphasizing anger management, brief interventions, and cognitive behavioral therapy, it serves adults and young adults across all genders. Notable programs focus on support for active military members, as well as specialized services for both adult men and women, ensuring personalized treatment for each client. La Frontera Center is committed to providing high-quality care and effective treatment plans to support individuals on their path to recovery.

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Situated in Tucson, Arizona, La Frontera Center delivers extensive addiction therapies and targeted support for those facing dual diagnoses of mental health and substance use disorders. They offer structured programs including intensive outpatient, outpatient, and standard outpatient care. The center emphasizes techniques like anger management, brief interventions, and cognitive behavioral therapy, creating personalized plans for adults, youth, and young adults across the gender spectrum. La Frontera Center is distinguished by its dedicated services for trauma survivors, victims of sexual abuse, and the particular challenges faced by adolescents. Patients can anticipate a supportive setting focused on delivering excellent, personalized care to foster recovery.

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Idaho Falls, ID

Lady Liberty Inc, located in Idaho Falls, ID, is a specialized facility dedicated to aiding adult women in their recovery from substance use disorders and co-occurring severe mental health conditions. The center provides a spectrum of care, including intensive outpatient programs, extended residential stays, and standard outpatient services. Their therapeutic methods incorporate strategies like 12-step facilitation and anger management techniques. Lady Liberty Inc places a significant emphasis on supporting individuals who have experienced intimate partner violence, sexual abuse, and domestic violence, fostering an environment conducive to healing and growth. They offer customized treatment plans for adults, seniors, and young adults, ensuring personalized care. For those searching for a professional and nurturing setting equipped to handle intricate challenges, Lady Liberty Inc is committed to guiding individuals through their recovery process.

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Nestled in Raceland, LA, Lafourche Behavioral Health delivers extensive outpatient care for adults battling substance use challenges. They also provide focused support for individuals experiencing co-occurring substance use disorders alongside serious mental health conditions in adults or significant emotional disruptions in children. The center utilizes diverse treatment modalities, including outpatient care with methadone, buprenorphine, or naltrexone, alongside standard outpatient services. Employing strategies such as anger management, brief intervention, and cognitive behavioral therapy, this facility is equipped to assist adolescents, adult men, and adult women. Catering to adults and seniors across all genders, Lafourche Behavioral Health is dedicated to offering superior, personalized treatment to foster enduring recovery.

Depression & Substance Use Disorder: Key Facts

Classification

Major Depressive Disorder + Substance Use Disorder (Dual Diagnosis)

Co-occurrence

~1 in 3 people with depression also have SUD (NIDA)

Prevalence

21 million adults with major depressive episode/year (NIMH)

Self-medication

Depression is the #1 reason for substance self-medication

Treatment approach

Integrated dual diagnosis (treat both simultaneously)

Key therapies

CBT, DBT, medication management, group therapy

Medications

SSRIs (non-addictive), SNRIs — safe during addiction treatment

Prognosis

Significantly better outcomes with integrated treatment vs sequential

If you or someone you know is experiencing suicidal thoughts, call 988 (Suicide & Crisis Lifeline) or text 988 immediately. Help is available 24/7.

Depression and Addiction: The Dual Diagnosis Connection

How depression and addiction feed each other

Depression and substance use disorder share a deeply intertwined relationship. Depression causes persistent feelings of emptiness, hopelessness, and emotional pain that drive many people toward alcohol or drugs as a form of self-medication. Substances may provide temporary relief, but they alter brain chemistry in ways that worsen depressive symptoms over time — creating a destructive cycle that accelerates both conditions.

The self-medication cycle

The self-medication cycle is the most common pathway from depression to addiction. A person experiencing persistent sadness, fatigue, or emotional numbness turns to alcohol, opioids, or stimulants to feel better temporarily. As tolerance builds, they need more of the substance to achieve the same relief. Meanwhile, the substance disrupts serotonin and dopamine regulation in the brain, deepening the depression. When the substance wears off, the depression returns worse than before — driving further substance use.

Why treating one without the other fails

Treating addiction without addressing underlying depression leaves the root cause intact. The person achieves sobriety but continues suffering from untreated depression, making relapse nearly inevitable as they seek relief. Conversely, treating depression without addressing active substance use is ineffective because ongoing drug or alcohol use undermines the neurochemical changes that antidepressants and therapy work to achieve. This is why dual diagnosis treatment — addressing both conditions simultaneously — produces significantly better outcomes than treating either condition alone.

Signs of Co-Occurring Depression and Substance Abuse

Recognizing co-occurring depression and substance abuse can be challenging because symptoms overlap. Watch for these warning signs:

Emotional and behavioral signs

  • Persistent sadness combined with increased substance use
  • Withdrawal from friends, family, and activities once enjoyed
  • Using drugs or alcohol specifically to cope with emptiness or hopelessness
  • Feelings of worthlessness or excessive guilt alongside substance use
  • Loss of motivation or interest in recovery efforts

Physical signs

  • Significant changes in sleep patterns — insomnia or oversleeping
  • Appetite and weight changes (loss or gain)
  • Chronic fatigue even with adequate rest
  • Increased substance tolerance requiring higher doses
  • Neglect of personal hygiene and self-care

How Dual Diagnosis Treatment Works

Integrated approach

Dual diagnosis treatment treats depression and addiction as interconnected conditions rather than separate problems. Instead of completing addiction treatment first and then addressing depression (the sequential approach that often fails), integrated programs work on both simultaneously. This means therapy sessions address how depressive thoughts drive substance use, while psychiatric care stabilizes mood to support sobriety.

Psychiatric evaluation during early sobriety

Accurate diagnosis of depression requires evaluation during a period of sobriety, because many substances can mimic or mask depressive symptoms. Alcohol is a depressant that causes sadness and lethargy. Stimulant withdrawal causes profound depression. A psychiatrist experienced in dual diagnosis will conduct thorough assessments during early sobriety to distinguish substance-induced mood changes from underlying major depressive disorder, ensuring the right treatment plan.

Coordinated care teams

Effective dual diagnosis programs use coordinated care teams where psychiatrists, addiction counselors, therapists, and medical staff communicate about each patient's progress. The psychiatrist managing antidepressant medication works closely with the addiction counselor guiding recovery, so treatment decisions account for both conditions. This prevents the common problem of one provider unknowingly undermining another's treatment plan.

Medication management alongside addiction treatment

One of the most important aspects of dual diagnosis care is safe medication management. Antidepressants like SSRIs and SNRIs are non-addictive and can be prescribed safely during addiction treatment. A psychiatrist monitors medication effectiveness, adjusts dosages, and watches for interactions — all while the person is actively working on recovery from substance use disorder.

Evidence-Based Therapies for Depression in Recovery

Cognitive Behavioral Therapy (CBT)

Cognitive Behavioral Therapy (CBT) is the gold standard for treating co-occurring depression and addiction. CBT helps identify negative thought patterns that drive both depressive episodes and substance use — such as "nothing will ever get better" or "I can't cope without drinking." Patients learn to challenge these distortions and replace them with realistic, constructive thinking. Research consistently shows CBT reduces both depressive symptoms and substance use relapse rates.

Dialectical Behavior Therapy (DBT)

Dialectical Behavior Therapy (DBT) is particularly effective for people with severe depression, emotional dysregulation, or self-harm behaviors alongside addiction. DBT teaches four core skill sets: mindfulness, distress tolerance, emotion regulation, and interpersonal effectiveness. These skills directly address the emotional pain that drives self-medication and provide healthier alternatives to substance use.

Group therapy

Group therapy combats the isolation that is central to both depression and addiction. Hearing others share similar struggles reduces shame and hopelessness. Dual diagnosis groups specifically address how depression and substance use interact, offering peer support from people who understand both conditions. Group settings also build social skills and accountability that support long-term recovery.

Medication management

Antidepressant medications are a critical component of treatment for many people with co-occurring depression and addiction. SSRIs (selective serotonin reuptake inhibitors) like sertraline and fluoxetine are first-line treatments because they are effective, well-tolerated, and — importantly — non-addictive. They carry no abuse potential and do not produce euphoria, making them safe to prescribe during addiction recovery. SNRIs like venlafaxine and duloxetine are also effective alternatives.

Levels of Care for Depression and Addiction

When residential treatment is needed

Residential treatment is recommended when depression is severe — particularly when suicidal ideation is present, when the person has made previous suicide attempts, or when outpatient treatment has failed. Residential programs provide 24/7 psychiatric monitoring, immediate medication adjustments, and a safe environment removed from triggers. People with severe addiction alongside major depression often need this level of structured support to stabilize both conditions.

Intensive Outpatient Programs (IOP)

Intensive Outpatient Programs provide 9–20 hours of structured therapy per week while allowing patients to live at home. IOP is appropriate for moderate depression with addiction, for people stepping down from residential care, or when the person has a stable living environment and support system. Dual diagnosis IOP programs include both addiction counseling and psychiatric services.

Outpatient care with medication management

Standard outpatient treatment works well for mild to moderate depression with substance use disorder, especially when combined with antidepressant medication. This typically involves weekly therapy sessions, regular psychiatric check-ins for medication management, and support group participation. Outpatient care allows people to maintain work, family, and daily responsibilities while receiving treatment.

Choosing the right level of care

The appropriate level of care depends on several factors: severity of depression (mild vs. severe with suicidal thoughts), severity of addiction, previous treatment attempts and outcomes, strength of social support, co-occurring medical conditions, and safety concerns. A professional assessment by a dual diagnosis specialist can determine the best starting point. Many people move through multiple levels of care as they progress in recovery.

Antidepressant Medications in Recovery

SSRIs: the first-line treatment

Selective serotonin reuptake inhibitors (SSRIs) such as sertraline (Zoloft), fluoxetine (Prozac), and escitalopram (Lexapro) are the most commonly prescribed antidepressants for people in addiction recovery. They work by increasing serotonin availability in the brain, gradually improving mood, sleep, and motivation over 4–6 weeks. SSRIs are not addictive, do not produce a high, and have no abuse potential — making them fundamentally different from the substances being treated.

SNRIs and bupropion

Serotonin-norepinephrine reuptake inhibitors (SNRIs) like venlafaxine (Effexor) and duloxetine (Cymbalta) target both serotonin and norepinephrine, which can be helpful for depression with prominent fatigue or chronic pain. Bupropion (Wellbutrin) is another option that acts on dopamine and norepinephrine — it can help with depression, low energy, and is also used to support smoking cessation. None of these medications carry addiction risk.

Addressing the stigma around psychiatric medication

Many people in recovery resist antidepressants because they feel taking any medication contradicts sobriety. This misconception is dangerous. Antidepressants are not mood-altering substances in the way drugs of abuse are — they restore normal brain chemistry rather than creating artificial highs. Untreated depression is one of the strongest predictors of addiction relapse. Taking prescribed, non-addictive medication to manage a medical condition is not a failure of recovery — it supports it.

Why stopping psychiatric meds leads to relapse

A common and harmful pattern occurs when people in recovery stop their antidepressants because they feel better, believe they no longer need them, or face pressure from others to be "medication-free." When depression returns — often within weeks — the emotional pain drives them back to substances. Antidepressant treatment for co-occurring depression should be maintained for at least 12 months after stabilization, and many people benefit from long-term maintenance. Any changes to psychiatric medication should be made gradually under medical supervision.

Frequently Asked Questions About Depression and Addiction

What is dual diagnosis treatment for depression and addiction?

Dual diagnosis treatment addresses both depression and substance use disorders simultaneously through integrated care. This approach recognizes that mental health and addiction affect each other and must be treated together for lasting recovery. Treatment includes psychiatric care, medication management, therapy (CBT, DBT), and specialized counseling that addresses both conditions comprehensively.

Can depression cause substance abuse?

Yes, depression significantly increases the risk of substance abuse. Many people self-medicate depression symptoms with alcohol or drugs, seeking temporary relief from emotional pain, low energy, or insomnia. However, substance use worsens depression long-term by disrupting serotonin and dopamine regulation, creating a vicious cycle. Proper treatment addresses root causes of depression while providing healthier coping strategies than substances.

Will antidepressants interfere with addiction treatment?

No, appropriate antidepressant medication actively supports recovery. Quality dual diagnosis programs work with psychiatrists to find effective antidepressant treatment while addressing addiction. Medications like SSRIs and SNRIs are non-addictive and help stabilize mood, making it easier to engage in therapy and maintain sobriety. Never stop psychiatric medications without medical guidance.

How do I find a treatment center for depression and addiction?

Look for centers explicitly offering dual diagnosis or co-occurring disorder treatment. Verify they have licensed mental health professionals, psychiatric services, medication management capabilities, and experience treating both conditions together. Use our directory to filter for dual diagnosis programs, read reviews, and verify accreditation. Contact admissions teams to discuss your specific needs.

Is residential treatment necessary for depression and addiction?

Not always. Treatment level depends on severity of both conditions, previous treatment attempts, safety concerns, and support system. Some people do well with intensive outpatient care plus medication management. Residential treatment provides 24/7 support for severe depression, suicide risk, or when outpatient treatment hasn't succeeded. A professional assessment determines the most appropriate level of care.

Can addiction cause depression or does depression cause addiction?

The relationship is bidirectional — it works both ways. Depression can lead to substance abuse through self-medication, as people use drugs or alcohol to escape emotional pain. At the same time, chronic substance use alters brain chemistry in ways that cause or worsen depression — alcohol is a central nervous system depressant, stimulant withdrawal causes profound depression, and opioid use disrupts the brain's natural mood regulation. In many cases, both conditions develop and reinforce each other simultaneously, which is why integrated dual diagnosis treatment is essential for lasting recovery.

Will I need antidepressants forever?

Not necessarily. Many people take antidepressants for 12–24 months after their mood stabilizes, then gradually taper off under medical supervision. However, some people with recurrent major depression (three or more episodes) benefit from long-term maintenance medication. The decision depends on depression severity, number of past episodes, family history, and individual response to treatment. What is critical is never stopping antidepressants abruptly — doing so can cause withdrawal symptoms and trigger relapse in both depression and addiction. Always work with your prescribing psychiatrist to make any medication changes.

Medical Review and Sources

Medically Reviewed Updated April 10, 2026

Reviewed by licensed addiction specialists. Information reflects current clinical guidance.

Sources:SAMHSA·NIDA·CDC

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