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Medically Reviewed Content
Updated: August 2026
Sources: SAMHSA, NIDA

Depression & Addiction Treatment Centers Near You

Depression and addiction frequently co-occur, requiring integrated treatment approaches. Find dual diagnosis treatment centers addressing both mental health and substance use disorders through coordinated care and evidence-based therapies.

Found 7,770 rehab centers specializing in depression across the United States.

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Find Depression and Addiction Treatment Centers Near You

Browse dual diagnosis treatment centers below. Filter for programs treating depression and substance abuse together.

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Lighthouse Recovery Institute

Lighthouse Recovery Institute, situated in Boynton Beach, FL, provides targeted care for individuals of all ages struggling with substance abuse and co-occurring mental health conditions. Their treatment modalities include intensive outpatient, outpatient, and partial hospitalization programs, integrated with proven methods like 12-step facilitation, anger management, and brief intervention strategies. Specialized offerings are available for active duty military personnel, adult men, and women. This facility extends its comprehensive services to adults and young adults across all genders, emphasizing personalized care plans and scientifically supported therapeutic techniques. Lighthouse Recovery Institute is recognized for its dedication to high-standard treatment and customized programs designed for sustained recovery.

Lighthouse Treatment Center

Situated in Anaheim, California, the Lighthouse Treatment Center provides a range of rehabilitation services designed for both adults and young adults dealing with substance abuse issues and associated mental health challenges. Emphasizing intensive outpatient care, long-term residential programs, and outpatient services, this center features tailored options for active military members, as well as programs for adult men and women. Employing evidence-driven methods such as 12-step support, anger management techniques, and brief therapeutic interventions, the facility guarantees personalized treatment that caters to each client's unique circumstances. The Lighthouse Treatment Center is dedicated to delivering high-quality care, making it a guiding light for individuals embarking on their recovery journey from addiction.

Lighthouse Treatment Center

Situated in Anaheim, CA, the Lighthouse Treatment Center delivers an extensive array of rehabilitation services targeting adults and young adults dealing with substance use issues and concurrent mental health challenges. The facility offers various treatment modalities, including detoxification, intensive outpatient, long-term residential, and outpatient programs, ensuring that care is personalized to fit each individual's requirements. The center employs methods such as 12-step facilitation, anger management, and brief interventions, promoting a comprehensive and effective recovery experience. Additionally, specialized programs are offered for active duty military, adult men, and adult women, with a focus on creating a secure and encouraging atmosphere for clients of both genders.

Lighthouse Treatment Center

Situated in Anaheim, California, Lighthouse Treatment Center delivers an extensive array of services to support individuals facing challenges related to substance abuse and concurrent mental health issues. The center offers a variety of programs including detoxification, intensive outpatient therapy, long-term residential support, and outpatient options. Catering to different populations, Lighthouse Treatment Center provides specialized paths for active duty service members, adult men and women, along with customized programs for young adults. By employing methodologies such as 12-step facilitation, anger management, and brief intervention, the center is committed to delivering tailored care for every individual. With an emphasis on high-quality, evidence-based strategies, this facility stands out as an exceptional choice for those in need of empathetic and effective addiction recovery solutions.

Lighthouse Treatment Center

Situated in Anaheim, California, Lighthouse Treatment Center provides extensive recovery programs for adults and young adults facing addiction and accompanying mental health challenges. The center features distinct programs for active military personnel, adult males, and adult females, offering intensive outpatient, extended residential, and standard outpatient care. Through methods like 12-step support, emotional regulation techniques, and short-term counseling, the center customizes treatment plans. Lighthouse Treatment Center distinguishes itself through its dedication to high standards of care and its integrated approach to treating both addiction and psychological concerns, promoting complete well-being for those in its care.

Lincoln Nova Vital Recovery

Situated in Ruston, Louisiana, Lincoln Nova Vital Recovery delivers extensive detox and treatment services for substance use disorders. The center offers a variety of options including intensive outpatient programs, outpatient services, and treatments involving methadone, buprenorphine, or naltrexone. Emphasizing methodologies such as 12-step programs, anger management, and brief intervention techniques, this facility serves adult men and women, including individuals in active military service. With a commitment to providing personalized care for adults and young adults of all genders, Lincoln Nova Vital Recovery stands out as a reliable option for those pursuing effective rehabilitation in the region.

Lionheart Recovery Center

Situated in Las Vegas, NV, Lionheart Recovery Center delivers thorough addiction treatment for both adults and young adults. The facility specializes in detox services, treatment for substance use disorders, and support for co-occurring mental health conditions. It offers long-term residential care within a nurturing atmosphere. The treatment methodology encompasses 12-step programs, anger management, and strategic interventions. Tailored programs are available for adult men, adult women, and those who have faced trauma. Emphasizing high-quality care, Lionheart Recovery Center is a reliable option for those in pursuit of customized and impactful rehabilitation solutions.

Lionrock Recovery
Kirkland, WA

Situated in Kirkland, Washington, Lionrock Recovery delivers a comprehensive suite of evidence-based therapies for individuals grappling with substance abuse and associated mental health challenges, serving both adults and young people. The center distinguishes itself with tailored programs for trauma survivors, adult men, and women, offering flexible treatment formats including intensive outpatient, outpatient, and standard outpatient care. Their therapeutic modalities encompass anger management techniques, brief intervention strategies, and cognitive behavioral therapy, accommodating individuals of all ages and genders. Renowned for its dedication to high-quality care and personalized recovery pathways, Lionrock Recovery stands out as a premier destination for effective and holistic addiction treatment.

Lincoln Treatment Center

The Lincoln Treatment Center, situated in Lincoln, NE, provides accessible outpatient addiction recovery services. Their comprehensive care model includes medication-assisted treatment options such as methadone, buprenorphine, and naltrexone. Recognizing diverse needs, they offer distinct programs for active military members, adult men, and adult women. Therapeutic interventions encompass anger management, brief intervention strategies, and cognitive behavioral therapy, all designed to tackle the complexities of substance use disorders. Serving both adults and young adults across genders, the center is committed to delivering individualized and impactful treatment plans to support each person's journey toward lasting sobriety.

Linn County Dept of Health Family

Situated in Albany, OR, the Linn County Dept of Health Family specializes in a wide range of substance use rehabilitation programs. The center offers intensive outpatient services, standard outpatient care, and brief intervention options. Employing proven methods like cognitive behavioral therapy and community reinforcement alongside vouchers, this facility serves adolescents, adult men, and adult women. With tailored programs designed for various demographics, including adults and seniors, the center prioritizes personalized care. Individuals can anticipate high-caliber, gender-specific treatment plans crafted to meet their distinct needs. For those in search of effective addiction recovery, the Linn County Dept of Health Family stands out as a trustworthy option.

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The Lighthouse Women's Residential Treatment Program located in Buffalo, NY, provides extended residential support for adult women facing challenges with substance use disorders alongside significant mental health issues or emotional difficulties. This facility features tailored treatment options for individuals who have experienced intimate partner violence, domestic abuse, and sexual trauma. By prioritizing 12-step methodologies, anger management techniques, and cognitive behavioral therapy, the center serves a diverse population, including adults, seniors, and young adults, within a nurturing and secure setting. With a strong emphasis on personalized care and research-supported methods, the program aims to deliver effective treatment for women on their journeys toward recovery and healing.

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Situated in Lima, OH, Lima Urban Minority Alcohol serves as a holistic rehabilitation center dedicated to addressing substance use disorders. It offers a range of services, including transitional housing and targeted support for individuals facing both addiction and serious mental health challenges. The center features various treatment options, such as intensive outpatient programs and outpatient care, alongside medications like methadone or buprenorphine, and naltrexone. Emphasizing techniques like 12-step support, anger management, and brief interventions, it caters to diverse groups, including adult men and women, teenagers, and older adults. Notably, the center specializes in creating programs that specifically support minority communities, striving to provide effective recovery solutions for those in need.

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Link and Option Center Inc, located in Hazel Crest, IL, specializes in outpatient treatment for individuals dealing with substance abuse, co-occurring conditions, and serious mental health challenges in adults, along with emotional issues in children. The center features tailored programs for adolescents, as well as separate services for adult men and women. It accommodates both adults and seniors, regardless of gender, and adopts a holistic method to rehabilitation. Prioritizing high-quality care, the facility develops customized treatment plans that align with each client's distinct path to recovery. For those searching for effective and tailored addiction support, Link and Option Center Inc offers valuable services that could meet your needs.

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Situated in South Holland, IL, Link and Option Center Inc provides extensive outpatient services for adults dealing with substance use and concurrent severe mental health challenges, as well as addressing emotional issues in children. The center features tailored programs for teenagers, adult men, and adult women, accommodating diverse age groups, including seniors. Emphasizing high-quality care, the facility adopts a holistic treatment philosophy. Both men and women looking for customized and impactful rehabilitation support can rely on the services offered at this center.

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At Link and Option Center Inc in South Holland, IL, we provide complete care for adults grappling with addiction and concurrent serious mental health challenges. Our offerings include robust intensive outpatient, outpatient, and standard outpatient treatment modalities. We embrace a holistic philosophy, serving adolescents, adult men, and adult women. Our services extend to adults and seniors of any gender, distinguished by our customized programs and high standards of care. Regardless of whether you require substantial support or less intensive outpatient options, our facility offers specialized interventions to meet individual requirements effectively.

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Situated in Las Vegas, NV, Lionheart Recovery Center Outpatient provides extensive treatment options for adults dealing with substance use issues, including those facing significant mental health challenges. The facility features a range of programs, such as intensive outpatient, outpatient, and day treatment, focusing on diverse therapeutic approaches including 12-step support, anger management, and short-term interventions. With an emphasis on trauma-informed care, this center serves adult men, women, and young adults. By delivering customized programs that address the specific needs of various age groups and genders, Lionheart Recovery Center Outpatient guarantees personalized care and assistance for every client.

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Saint Petersburg, FL

Lionrock Recovery, situated in Saint Petersburg, FL, provides thorough care for adults and young adults struggling with addiction and co-occurring mental health conditions. Their structured outpatient programs, including intensive, standard, and regular levels, utilize proven therapies such as cognitive behavioral therapy and anger management. This center is equipped to offer tailored support for adult women, those with a history of trauma, and individuals dealing with dual diagnoses of mental health and substance use disorders. Prioritizing personalized and high-quality rehabilitation, Lionrock Recovery serves both male and female individuals in their recovery journey.

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Scottsdale, AZ

At Lionrock Recovery in Scottsdale, AZ, individuals seeking help for substance use and co-occurring mental health challenges receive comprehensive, evidence-backed care. This center provides various levels of support, including intensive outpatient, outpatient, and standard outpatient services. Their therapeutic modalities encompass anger management, brief intervention techniques, and cognitive behavioral therapy. They also offer tailored programs designed for adult men, adult women, and those who have undergone traumatic experiences. Lionrock Recovery is dedicated to delivering high-quality, personalized treatment for adults and young adults of all gender identities, aiming to foster enduring recovery.

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Campbell, CA

Situated in Campbell, California, Lionrock Recovery is dedicated to providing all-encompassing care for individuals struggling with substance use disorders, including those facing concurrent mental health challenges. Their program offerings include intensive outpatient, outpatient, and standard outpatient services, all rooted in proven therapeutic methods such as cognitive behavioral therapy and anger management techniques. Lionrock Recovery is particularly adept at trauma-informed care, developing customized treatment plans for adult men, adult women, and individuals with a history of trauma. The center is equipped to support both male and female clients, ensuring high-quality, personalized care to facilitate their path toward lasting sobriety.

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Lionrock Recovery, located in Maumee, OH, provides an array of treatment alternatives for adults and young adults dealing with substance use disorders and accompanying mental health challenges. The center employs evidence-based methodologies such as cognitive behavioral therapy and anger management strategies, offering tailored programs for adult men, adult women, and individuals with a history of trauma. Prioritizing personalized care, Lionrock Recovery is dedicated to delivering effective support for both male and female clients on their path to overcoming addiction.

Depression & Substance Use Disorder: Key Facts

Classification

Major Depressive Disorder + Substance Use Disorder (Dual Diagnosis)

Co-occurrence

~1 in 3 people with depression also have SUD (NIDA)

Prevalence

21 million adults with major depressive episode/year (NIMH)

Self-medication

Depression is the #1 reason for substance self-medication

Treatment approach

Integrated dual diagnosis (treat both simultaneously)

Key therapies

CBT, DBT, medication management, group therapy

Medications

SSRIs (non-addictive), SNRIs — safe during addiction treatment

Prognosis

Significantly better outcomes with integrated treatment vs sequential

If you or someone you know is experiencing suicidal thoughts, call 988 (Suicide & Crisis Lifeline) or text 988 immediately. Help is available 24/7.

Depression and Addiction: The Dual Diagnosis Connection

How depression and addiction feed each other

Depression and substance use disorder share a deeply intertwined relationship. Depression causes persistent feelings of emptiness, hopelessness, and emotional pain that drive many people toward alcohol or drugs as a form of self-medication. Substances may provide temporary relief, but they alter brain chemistry in ways that worsen depressive symptoms over time — creating a destructive cycle that accelerates both conditions.

The self-medication cycle

The self-medication cycle is the most common pathway from depression to addiction. A person experiencing persistent sadness, fatigue, or emotional numbness turns to alcohol, opioids, or stimulants to feel better temporarily. As tolerance builds, they need more of the substance to achieve the same relief. Meanwhile, the substance disrupts serotonin and dopamine regulation in the brain, deepening the depression. When the substance wears off, the depression returns worse than before — driving further substance use.

Why treating one without the other fails

Treating addiction without addressing underlying depression leaves the root cause intact. The person achieves sobriety but continues suffering from untreated depression, making relapse nearly inevitable as they seek relief. Conversely, treating depression without addressing active substance use is ineffective because ongoing drug or alcohol use undermines the neurochemical changes that antidepressants and therapy work to achieve. This is why dual diagnosis treatment — addressing both conditions simultaneously — produces significantly better outcomes than treating either condition alone.

Signs of Co-Occurring Depression and Substance Abuse

Recognizing co-occurring depression and substance abuse can be challenging because symptoms overlap. Watch for these warning signs:

Emotional and behavioral signs

  • Persistent sadness combined with increased substance use
  • Withdrawal from friends, family, and activities once enjoyed
  • Using drugs or alcohol specifically to cope with emptiness or hopelessness
  • Feelings of worthlessness or excessive guilt alongside substance use
  • Loss of motivation or interest in recovery efforts

Physical signs

  • Significant changes in sleep patterns — insomnia or oversleeping
  • Appetite and weight changes (loss or gain)
  • Chronic fatigue even with adequate rest
  • Increased substance tolerance requiring higher doses
  • Neglect of personal hygiene and self-care

How Dual Diagnosis Treatment Works

Integrated approach

Dual diagnosis treatment treats depression and addiction as interconnected conditions rather than separate problems. Instead of completing addiction treatment first and then addressing depression (the sequential approach that often fails), integrated programs work on both simultaneously. This means therapy sessions address how depressive thoughts drive substance use, while psychiatric care stabilizes mood to support sobriety.

Psychiatric evaluation during early sobriety

Accurate diagnosis of depression requires evaluation during a period of sobriety, because many substances can mimic or mask depressive symptoms. Alcohol is a depressant that causes sadness and lethargy. Stimulant withdrawal causes profound depression. A psychiatrist experienced in dual diagnosis will conduct thorough assessments during early sobriety to distinguish substance-induced mood changes from underlying major depressive disorder, ensuring the right treatment plan.

Coordinated care teams

Effective dual diagnosis programs use coordinated care teams where psychiatrists, addiction counselors, therapists, and medical staff communicate about each patient's progress. The psychiatrist managing antidepressant medication works closely with the addiction counselor guiding recovery, so treatment decisions account for both conditions. This prevents the common problem of one provider unknowingly undermining another's treatment plan.

Medication management alongside addiction treatment

One of the most important aspects of dual diagnosis care is safe medication management. Antidepressants like SSRIs and SNRIs are non-addictive and can be prescribed safely during addiction treatment. A psychiatrist monitors medication effectiveness, adjusts dosages, and watches for interactions — all while the person is actively working on recovery from substance use disorder.

Evidence-Based Therapies for Depression in Recovery

Cognitive Behavioral Therapy (CBT)

Cognitive Behavioral Therapy (CBT) is the gold standard for treating co-occurring depression and addiction. CBT helps identify negative thought patterns that drive both depressive episodes and substance use — such as "nothing will ever get better" or "I can't cope without drinking." Patients learn to challenge these distortions and replace them with realistic, constructive thinking. Research consistently shows CBT reduces both depressive symptoms and substance use relapse rates.

Dialectical Behavior Therapy (DBT)

Dialectical Behavior Therapy (DBT) is particularly effective for people with severe depression, emotional dysregulation, or self-harm behaviors alongside addiction. DBT teaches four core skill sets: mindfulness, distress tolerance, emotion regulation, and interpersonal effectiveness. These skills directly address the emotional pain that drives self-medication and provide healthier alternatives to substance use.

Group therapy

Group therapy combats the isolation that is central to both depression and addiction. Hearing others share similar struggles reduces shame and hopelessness. Dual diagnosis groups specifically address how depression and substance use interact, offering peer support from people who understand both conditions. Group settings also build social skills and accountability that support long-term recovery.

Medication management

Antidepressant medications are a critical component of treatment for many people with co-occurring depression and addiction. SSRIs (selective serotonin reuptake inhibitors) like sertraline and fluoxetine are first-line treatments because they are effective, well-tolerated, and — importantly — non-addictive. They carry no abuse potential and do not produce euphoria, making them safe to prescribe during addiction recovery. SNRIs like venlafaxine and duloxetine are also effective alternatives.

Levels of Care for Depression and Addiction

When residential treatment is needed

Residential treatment is recommended when depression is severe — particularly when suicidal ideation is present, when the person has made previous suicide attempts, or when outpatient treatment has failed. Residential programs provide 24/7 psychiatric monitoring, immediate medication adjustments, and a safe environment removed from triggers. People with severe addiction alongside major depression often need this level of structured support to stabilize both conditions.

Intensive Outpatient Programs (IOP)

Intensive Outpatient Programs provide 9–20 hours of structured therapy per week while allowing patients to live at home. IOP is appropriate for moderate depression with addiction, for people stepping down from residential care, or when the person has a stable living environment and support system. Dual diagnosis IOP programs include both addiction counseling and psychiatric services.

Outpatient care with medication management

Standard outpatient treatment works well for mild to moderate depression with substance use disorder, especially when combined with antidepressant medication. This typically involves weekly therapy sessions, regular psychiatric check-ins for medication management, and support group participation. Outpatient care allows people to maintain work, family, and daily responsibilities while receiving treatment.

Choosing the right level of care

The appropriate level of care depends on several factors: severity of depression (mild vs. severe with suicidal thoughts), severity of addiction, previous treatment attempts and outcomes, strength of social support, co-occurring medical conditions, and safety concerns. A professional assessment by a dual diagnosis specialist can determine the best starting point. Many people move through multiple levels of care as they progress in recovery.

Antidepressant Medications in Recovery

SSRIs: the first-line treatment

Selective serotonin reuptake inhibitors (SSRIs) such as sertraline (Zoloft), fluoxetine (Prozac), and escitalopram (Lexapro) are the most commonly prescribed antidepressants for people in addiction recovery. They work by increasing serotonin availability in the brain, gradually improving mood, sleep, and motivation over 4–6 weeks. SSRIs are not addictive, do not produce a high, and have no abuse potential — making them fundamentally different from the substances being treated.

SNRIs and bupropion

Serotonin-norepinephrine reuptake inhibitors (SNRIs) like venlafaxine (Effexor) and duloxetine (Cymbalta) target both serotonin and norepinephrine, which can be helpful for depression with prominent fatigue or chronic pain. Bupropion (Wellbutrin) is another option that acts on dopamine and norepinephrine — it can help with depression, low energy, and is also used to support smoking cessation. None of these medications carry addiction risk.

Addressing the stigma around psychiatric medication

Many people in recovery resist antidepressants because they feel taking any medication contradicts sobriety. This misconception is dangerous. Antidepressants are not mood-altering substances in the way drugs of abuse are — they restore normal brain chemistry rather than creating artificial highs. Untreated depression is one of the strongest predictors of addiction relapse. Taking prescribed, non-addictive medication to manage a medical condition is not a failure of recovery — it supports it.

Why stopping psychiatric meds leads to relapse

A common and harmful pattern occurs when people in recovery stop their antidepressants because they feel better, believe they no longer need them, or face pressure from others to be "medication-free." When depression returns — often within weeks — the emotional pain drives them back to substances. Antidepressant treatment for co-occurring depression should be maintained for at least 12 months after stabilization, and many people benefit from long-term maintenance. Any changes to psychiatric medication should be made gradually under medical supervision.

Frequently Asked Questions About Depression and Addiction

What is dual diagnosis treatment for depression and addiction?

Dual diagnosis treatment addresses both depression and substance use disorders simultaneously through integrated care. This approach recognizes that mental health and addiction affect each other and must be treated together for lasting recovery. Treatment includes psychiatric care, medication management, therapy (CBT, DBT), and specialized counseling that addresses both conditions comprehensively.

Can depression cause substance abuse?

Yes, depression significantly increases the risk of substance abuse. Many people self-medicate depression symptoms with alcohol or drugs, seeking temporary relief from emotional pain, low energy, or insomnia. However, substance use worsens depression long-term by disrupting serotonin and dopamine regulation, creating a vicious cycle. Proper treatment addresses root causes of depression while providing healthier coping strategies than substances.

Will antidepressants interfere with addiction treatment?

No, appropriate antidepressant medication actively supports recovery. Quality dual diagnosis programs work with psychiatrists to find effective antidepressant treatment while addressing addiction. Medications like SSRIs and SNRIs are non-addictive and help stabilize mood, making it easier to engage in therapy and maintain sobriety. Never stop psychiatric medications without medical guidance.

How do I find a treatment center for depression and addiction?

Look for centers explicitly offering dual diagnosis or co-occurring disorder treatment. Verify they have licensed mental health professionals, psychiatric services, medication management capabilities, and experience treating both conditions together. Use our directory to filter for dual diagnosis programs, read reviews, and verify accreditation. Contact admissions teams to discuss your specific needs.

Is residential treatment necessary for depression and addiction?

Not always. Treatment level depends on severity of both conditions, previous treatment attempts, safety concerns, and support system. Some people do well with intensive outpatient care plus medication management. Residential treatment provides 24/7 support for severe depression, suicide risk, or when outpatient treatment hasn't succeeded. A professional assessment determines the most appropriate level of care.

Can addiction cause depression or does depression cause addiction?

The relationship is bidirectional — it works both ways. Depression can lead to substance abuse through self-medication, as people use drugs or alcohol to escape emotional pain. At the same time, chronic substance use alters brain chemistry in ways that cause or worsen depression — alcohol is a central nervous system depressant, stimulant withdrawal causes profound depression, and opioid use disrupts the brain's natural mood regulation. In many cases, both conditions develop and reinforce each other simultaneously, which is why integrated dual diagnosis treatment is essential for lasting recovery.

Will I need antidepressants forever?

Not necessarily. Many people take antidepressants for 12–24 months after their mood stabilizes, then gradually taper off under medical supervision. However, some people with recurrent major depression (three or more episodes) benefit from long-term maintenance medication. The decision depends on depression severity, number of past episodes, family history, and individual response to treatment. What is critical is never stopping antidepressants abruptly — doing so can cause withdrawal symptoms and trigger relapse in both depression and addiction. Always work with your prescribing psychiatrist to make any medication changes.

Medical Review and Sources

Medically Reviewed Updated April 10, 2026

Reviewed by licensed addiction specialists. Information reflects current clinical guidance.

Sources:SAMHSA·NIDA·CDC

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