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Medically Reviewed Content
Updated: August 2026
Sources: SAMHSA, NIDA

Depression & Addiction Treatment Centers Near You

Depression and addiction frequently co-occur, requiring integrated treatment approaches. Find dual diagnosis treatment centers addressing both mental health and substance use disorders through coordinated care and evidence-based therapies.

Found 7,770 rehab centers specializing in depression across the United States.

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Find Depression and Addiction Treatment Centers Near You

Browse dual diagnosis treatment centers below. Filter for programs treating depression and substance abuse together.

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MCCA Trinity Glen Mens Program

Situated in Sharon, CT, the MCCA Trinity Glen Mens Program provides extended residential treatment for adult males dealing with substance use issues alongside mental health challenges. This center offers round-the-clock support and focuses on treating individuals experiencing significant emotional difficulties. By employing techniques such as 12-step facilitation, anger management, and cognitive behavioral therapy, the program serves a diverse range of clients, including adults, seniors, and young adults, in need of thorough and gender-tailored rehabilitation options. The facility prioritizes high-quality care and assistance for those navigating their recovery journeys, particularly those with intricate needs.

MCCA Trinity Glen Womens Program

MCCA Trinity Glen Women's Program, situated in Kent, CT, provides exceptional long-term residential treatment for adult women facing substance use challenges, particularly those with concurrent mental health issues. This center emphasizes support for pregnant and postpartum women, ensuring a nurturing environment that meets their specific requirements. With a strong commitment to 12-step practices, anger management, and cognitive behavioral therapy, the program offers a holistic approach to care for various age groups, including children experiencing significant emotional challenges. MCCA Trinity Glen Women's Program is devoted to offering superior, gender-responsive treatment that inspires women throughout their healing process.

McCall Behavioral Health Network

McCall Behavioral Health Network, located in Torrington, CT, provides a wide range of substance abuse treatment options, including intensive outpatient programs, standard outpatient services, and outpatient care with methadone or buprenorphine and naltrexone. Emphasizing evidence-based methodologies such as anger management, brief intervention strategies, and cognitive behavioral therapy, this center offers tailored programs for adolescents and adults, regardless of gender. With a commitment to delivering high-quality care, McCall Behavioral Health Network is dedicated to helping individuals of all ages navigate their journey to recovery from addiction.

McCall Behavioral Health Network

McCall Behavioral Health Network, located in Torrington, CT, specializes in extensive substance use recovery in a nurturing setting. The center features long-term residential programs, transitional housing, and sober living arrangements. Employing proven methods such as cognitive behavioral therapy and motivational interviewing, the facility emphasizes anger management and trauma-sensitive care. Customized treatment plans cater to adult men and women, including young adults, ensuring each individual receives the attention they need. With a distinct emphasis on supporting those who have faced trauma, McCall Behavioral Health Network provides exceptional care for individuals on their recovery journey. Opt for this center for gender-specific treatment and a comprehensive rehabilitation strategy.

McCall Behavioral Health Network

McCall Behavioral Health Network, located in Danbury, CT, specializes in treating substance use issues and co-existing mental health conditions for both adults and children. The center offers various programs, including both intensive outpatient and regular outpatient services, utilizing treatments such as methadone/buprenorphine and naltrexone. Emphasizing 12-step strategies, anger management, and cognitive behavioral therapy, McCall tailors its approach to suit the uniqueness of each individual. There are specialized programs available for adult men and women, as well as clients facing dual diagnoses. This center extends its comprehensive services to all adults and young adults, fostering a compassionate environment to support individuals on their journey to sustainable recovery.

McDermott Center/Haymarket Ctr

McDermott Center/Haymarket Ctr, located in Chicago, IL, provides extensive treatment options for adult men dealing with both substance use issues and significant mental health challenges. Their inpatient and residential services integrate 12-step methodologies along with anger management techniques, delivering personalized care for every patient. The center also features specialized programs aimed at active duty military personnel, adult males, and individuals who have experienced intimate partner violence, ensuring focused assistance. Dedicated to serving adults, seniors, and young adults, this center emphasizes high-quality care within a nurturing and secure atmosphere. If you or someone you know is in need of effective, individualized treatment, McDermott Center/Haymarket Ctr is ready to assist.

MCCA
Danbury, CT

MCCA, located in Danbury, CT, stands as a premier facility dedicated to the recovery of individuals struggling with addiction and concurrent mental health conditions. This center extends its specialized services to both adults and young individuals, encompassing a broad spectrum of care. They offer various treatment modalities, including round-the-clock residential programs, intensive outpatient services, and full-service hospital inpatient care, all designed to address each person's unique journey. MCCA employs proven therapeutic strategies such as facilitating participation in 12-step programs, teaching anger management skills, and utilizing short-term intervention techniques. Distinctive programs are available for adult men, women, and survivors of sexual trauma. Catering to all genders across adult and young adult populations, MCCA is committed to delivering high-quality, empathetic support to those on their path to overcoming substance dependence and mental health issues.

MCCA
Danbury, CT

The MCCA rehabilitation center in Danbury, CT, is dedicated to assisting people in their recovery process. They offer a complete spectrum of care, encompassing detox services, substance abuse treatment, and options for supervised and independent living. The center supports adult men and women with various treatment modalities, including intensive outpatient, outpatient, and outpatient detox programs, serving both adults and young adults. MCCA also features specialized programs for active military members and employs diverse therapeutic strategies like 12-step support, anger management techniques, and brief intervention to provide tailored assistance for each person's specific requirements.

MCCA
Danbury, CT

MCCA, situated in Danbury, Connecticut, is a respected facility dedicated to assisting individuals with substance use disorders. They offer various levels of care, including intensive outpatient, standard outpatient, and less structured outpatient services, serving adults and young adults of any gender. MCCA has dedicated treatment tracks for active duty military members, adult men, and adult women. Their therapeutic strategies incorporate 12-step facilitation, anger management techniques, and brief intervention methods, promoting personalized and thorough recovery plans. Prioritizing excellence in care and customized treatment, MCCA is a dependable choice for individuals pursuing successful recovery from addiction.

McCall Behavioral Health Network

McCall Behavioral Health Network in Waterbury, CT, provides dedicated long-term residential care for adult males struggling with addiction and accompanying mental health conditions. The center employs scientifically supported therapeutic methods, including 12-step programs, emotional regulation techniques, and cognitive behavioral interventions, to meet the distinct requirements of its residents. Focusing on dual diagnoses of substance abuse and severe mental health disorders, McCall Behavioral Health Network supports adults, older adults, and younger adults within a gender-specific setting. This institution is recognized for its thorough treatment plans designed for those facing multifaceted difficulties.

MCCA
Derby, CT

Situated in Derby, CT, MCCA delivers thorough addiction recovery care across multiple service tiers, encompassing intensive outpatient, standard outpatient, and medication-assisted treatment options like methadone, buprenorphine, or naltrexone. The facility is particularly skilled in employing strategies such as anger management, brief intervention, and cognitive behavioral therapy. Distinctive treatment tracks are available for adult men, adult women, and individuals facing dual diagnoses of mental health and substance use challenges. MCCA extends its services to adults and young adults of all genders, emphasizing personalized care plans that address the individual requirements of each person. The center is recognized for its commitment to superior, scientifically-backed therapies, establishing it as a premier destination for individuals pursuing effective and customized addiction treatment.

McCullough Vargas and Associates

McCullough Vargas and Associates in Hillsdale, MI, provides comprehensive outpatient care for individuals struggling with substance use disorders, including specialized support for co-occurring mental health and emotional challenges in adults and children. Their therapeutic modalities encompass 12-step integration, anger management techniques, and brief intervention strategies. This center tailors its services to meet the unique needs of adult men, adult women, and survivors of intimate partner or domestic violence. Catering to a diverse population of adults and young adults, McCullough Vargas and Associates is dedicated to offering effective and personalized rehabilitation.

McDermott Center/Haymarket Ctr

Situated in Chicago, IL, the McDermott Center/Haymarket Ctr delivers an extensive range of addiction recovery services for both adults and young adults. This center features various programs, including hospital inpatient care, intensive outpatient options, and long-term residential support, all aimed at detoxification, addressing substance use issues, and treating co-occurring mental health disorders. It offers tailored programs for different groups, such as active military members, men, and women. Employing strategies such as the 12-step model, anger management techniques, and brief intervention methods, the facility guarantees personalized treatment. The McDermott Center/Haymarket Ctr is committed to providing exceptional support for those pursuing recovery from substance use and mental health difficulties.

McDermott Center/Haymarket Ctr

The McDermott Center/Haymarket Ctr, located in Chicago, IL, specializes in addressing substance use disorders specifically for adult males dealing with serious mental health issues simultaneously. This center offers a range of services, including hospital inpatient care, round-the-clock hospital treatment, and extended residential programs. Emphasizing methods such as 12-step support, anger management, and brief intervention techniques, it serves various groups, including active military personnel, adult men, and individuals affected by intimate partner violence. Catering to adults, seniors, and younger adults, McDermott Center/Haymarket Ctr prioritizes quality services in a male-exclusive setting. If you or someone close to you is in need of comprehensive addiction recovery options tailored to individual needs, this facility is committed to delivering effective and empathetic support.

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Cohasset, MA

MCAT LLC in Cohasset, MA, is dedicated to providing expert detox and addiction care. They offer live-in detox, round-the-clock residential stays, and shorter-term residential care for adult men and women, as well as active military members. Their methods include 12-step support, emotional regulation training, and quick-response counseling, serving both adults and adolescents. Committed to excellent service, MCAT LLC aims to guide individuals toward sustained wellness with individualized plans that meet everyone's specific requirements.

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Bridgeport, CT

MCCA, situated in Bridgeport, CT, delivers complete care for adults and young adults grappling with substance use disorders and co-occurring mental health conditions. The facility offers robust intensive outpatient and outpatient programs, featuring medication-assisted treatment with methadone, buprenorphine, or naltrexone. Their approach integrates anger management, cognitive behavioral therapy, and the Matrix Model, customizing interventions for each person's unique journey. Dedicated programs cater to active duty military personnel, as well as adult men and women. MCCA serves both male and female individuals, committed to providing excellent support throughout their recovery process. For those in need of expert addiction treatment, this center offers a nurturing space for healing and lasting change.

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McCall Behavioral Health Network, located in Waterbury, CT, provides an extensive array of targeted therapies for both substance abuse and interconnected mental health disorders affecting adults and youth. Offering intensive outpatient services, outpatient programs, and medication-assisted treatments, the center focuses on tailored care through proven methodologies like 12-step facilitation, anger management, and cognitive behavioral therapy. Dedicated programs are designed for adult males, females, and those facing dual diagnoses. The facility caters to a diverse clientele of all genders, emphasizing high-quality care and customized treatment to foster enduring recovery.

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McCall Behavioral Health Network, situated in Winsted, CT, specializes in outpatient treatment for substance use and offers targeted support for individuals dealing with co-occurring mental health issues. This center presents various therapeutic options, including outpatient services utilizing methadone, buprenorphine, or naltrexone, alongside routine outpatient counseling. Emphasizing anger management, quick intervention strategies, and cognitive behavioral therapy, the facility serves adult men and women, as well as young adults, in need of holistic care. Clients receive customized programs specifically aimed at addressing both mental health and substance use challenges, ensuring a high standard of individualized treatment for everyone.

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Albany, NY

McCarty Avenue, situated in Albany, NY, provides extensive substance abuse treatment for adult males within a secure and nurturing setting. The center's expertise lies in extended residential stays, inpatient detoxification services, and round-the-clock residential care. Employing scientifically validated methods like anger management, cognitive behavioral therapy, and motivational interviewing, the facility delivers personalized interventions for addiction and co-occurring psychological health issues. Specialized services are available for those who have endured intimate partner violence, domestic abuse, and sexual trauma. Catering specifically to adult, senior, and young adult men, McCarty Avenue is dedicated to offering superior treatment and assistance for individuals pursuing freedom from addiction.

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McCullough Vargas and Associates, located in Adrian, MI, provides a wide range of substance use disorder treatments and specialized support for individuals facing significant mental health challenges concurrently. The center offers various treatment modalities, including intensive outpatient and standard outpatient services, specifically designed for adults and seniors. Their customized programs encompass 12-step support, anger management strategies, and brief intervention approaches to facilitate a comprehensive recovery journey. Additionally, the center features distinct programs tailored for adult men and women, as well as those impacted by intimate partner violence, making it a unique choice for many. The facility is dedicated to delivering high-quality care to both male and female clients, aiming for meaningful and lasting rehabilitation results.

Depression & Substance Use Disorder: Key Facts

Classification

Major Depressive Disorder + Substance Use Disorder (Dual Diagnosis)

Co-occurrence

~1 in 3 people with depression also have SUD (NIDA)

Prevalence

21 million adults with major depressive episode/year (NIMH)

Self-medication

Depression is the #1 reason for substance self-medication

Treatment approach

Integrated dual diagnosis (treat both simultaneously)

Key therapies

CBT, DBT, medication management, group therapy

Medications

SSRIs (non-addictive), SNRIs — safe during addiction treatment

Prognosis

Significantly better outcomes with integrated treatment vs sequential

If you or someone you know is experiencing suicidal thoughts, call 988 (Suicide & Crisis Lifeline) or text 988 immediately. Help is available 24/7.

Depression and Addiction: The Dual Diagnosis Connection

How depression and addiction feed each other

Depression and substance use disorder share a deeply intertwined relationship. Depression causes persistent feelings of emptiness, hopelessness, and emotional pain that drive many people toward alcohol or drugs as a form of self-medication. Substances may provide temporary relief, but they alter brain chemistry in ways that worsen depressive symptoms over time — creating a destructive cycle that accelerates both conditions.

The self-medication cycle

The self-medication cycle is the most common pathway from depression to addiction. A person experiencing persistent sadness, fatigue, or emotional numbness turns to alcohol, opioids, or stimulants to feel better temporarily. As tolerance builds, they need more of the substance to achieve the same relief. Meanwhile, the substance disrupts serotonin and dopamine regulation in the brain, deepening the depression. When the substance wears off, the depression returns worse than before — driving further substance use.

Why treating one without the other fails

Treating addiction without addressing underlying depression leaves the root cause intact. The person achieves sobriety but continues suffering from untreated depression, making relapse nearly inevitable as they seek relief. Conversely, treating depression without addressing active substance use is ineffective because ongoing drug or alcohol use undermines the neurochemical changes that antidepressants and therapy work to achieve. This is why dual diagnosis treatment — addressing both conditions simultaneously — produces significantly better outcomes than treating either condition alone.

Signs of Co-Occurring Depression and Substance Abuse

Recognizing co-occurring depression and substance abuse can be challenging because symptoms overlap. Watch for these warning signs:

Emotional and behavioral signs

  • Persistent sadness combined with increased substance use
  • Withdrawal from friends, family, and activities once enjoyed
  • Using drugs or alcohol specifically to cope with emptiness or hopelessness
  • Feelings of worthlessness or excessive guilt alongside substance use
  • Loss of motivation or interest in recovery efforts

Physical signs

  • Significant changes in sleep patterns — insomnia or oversleeping
  • Appetite and weight changes (loss or gain)
  • Chronic fatigue even with adequate rest
  • Increased substance tolerance requiring higher doses
  • Neglect of personal hygiene and self-care

How Dual Diagnosis Treatment Works

Integrated approach

Dual diagnosis treatment treats depression and addiction as interconnected conditions rather than separate problems. Instead of completing addiction treatment first and then addressing depression (the sequential approach that often fails), integrated programs work on both simultaneously. This means therapy sessions address how depressive thoughts drive substance use, while psychiatric care stabilizes mood to support sobriety.

Psychiatric evaluation during early sobriety

Accurate diagnosis of depression requires evaluation during a period of sobriety, because many substances can mimic or mask depressive symptoms. Alcohol is a depressant that causes sadness and lethargy. Stimulant withdrawal causes profound depression. A psychiatrist experienced in dual diagnosis will conduct thorough assessments during early sobriety to distinguish substance-induced mood changes from underlying major depressive disorder, ensuring the right treatment plan.

Coordinated care teams

Effective dual diagnosis programs use coordinated care teams where psychiatrists, addiction counselors, therapists, and medical staff communicate about each patient's progress. The psychiatrist managing antidepressant medication works closely with the addiction counselor guiding recovery, so treatment decisions account for both conditions. This prevents the common problem of one provider unknowingly undermining another's treatment plan.

Medication management alongside addiction treatment

One of the most important aspects of dual diagnosis care is safe medication management. Antidepressants like SSRIs and SNRIs are non-addictive and can be prescribed safely during addiction treatment. A psychiatrist monitors medication effectiveness, adjusts dosages, and watches for interactions — all while the person is actively working on recovery from substance use disorder.

Evidence-Based Therapies for Depression in Recovery

Cognitive Behavioral Therapy (CBT)

Cognitive Behavioral Therapy (CBT) is the gold standard for treating co-occurring depression and addiction. CBT helps identify negative thought patterns that drive both depressive episodes and substance use — such as "nothing will ever get better" or "I can't cope without drinking." Patients learn to challenge these distortions and replace them with realistic, constructive thinking. Research consistently shows CBT reduces both depressive symptoms and substance use relapse rates.

Dialectical Behavior Therapy (DBT)

Dialectical Behavior Therapy (DBT) is particularly effective for people with severe depression, emotional dysregulation, or self-harm behaviors alongside addiction. DBT teaches four core skill sets: mindfulness, distress tolerance, emotion regulation, and interpersonal effectiveness. These skills directly address the emotional pain that drives self-medication and provide healthier alternatives to substance use.

Group therapy

Group therapy combats the isolation that is central to both depression and addiction. Hearing others share similar struggles reduces shame and hopelessness. Dual diagnosis groups specifically address how depression and substance use interact, offering peer support from people who understand both conditions. Group settings also build social skills and accountability that support long-term recovery.

Medication management

Antidepressant medications are a critical component of treatment for many people with co-occurring depression and addiction. SSRIs (selective serotonin reuptake inhibitors) like sertraline and fluoxetine are first-line treatments because they are effective, well-tolerated, and — importantly — non-addictive. They carry no abuse potential and do not produce euphoria, making them safe to prescribe during addiction recovery. SNRIs like venlafaxine and duloxetine are also effective alternatives.

Levels of Care for Depression and Addiction

When residential treatment is needed

Residential treatment is recommended when depression is severe — particularly when suicidal ideation is present, when the person has made previous suicide attempts, or when outpatient treatment has failed. Residential programs provide 24/7 psychiatric monitoring, immediate medication adjustments, and a safe environment removed from triggers. People with severe addiction alongside major depression often need this level of structured support to stabilize both conditions.

Intensive Outpatient Programs (IOP)

Intensive Outpatient Programs provide 9–20 hours of structured therapy per week while allowing patients to live at home. IOP is appropriate for moderate depression with addiction, for people stepping down from residential care, or when the person has a stable living environment and support system. Dual diagnosis IOP programs include both addiction counseling and psychiatric services.

Outpatient care with medication management

Standard outpatient treatment works well for mild to moderate depression with substance use disorder, especially when combined with antidepressant medication. This typically involves weekly therapy sessions, regular psychiatric check-ins for medication management, and support group participation. Outpatient care allows people to maintain work, family, and daily responsibilities while receiving treatment.

Choosing the right level of care

The appropriate level of care depends on several factors: severity of depression (mild vs. severe with suicidal thoughts), severity of addiction, previous treatment attempts and outcomes, strength of social support, co-occurring medical conditions, and safety concerns. A professional assessment by a dual diagnosis specialist can determine the best starting point. Many people move through multiple levels of care as they progress in recovery.

Antidepressant Medications in Recovery

SSRIs: the first-line treatment

Selective serotonin reuptake inhibitors (SSRIs) such as sertraline (Zoloft), fluoxetine (Prozac), and escitalopram (Lexapro) are the most commonly prescribed antidepressants for people in addiction recovery. They work by increasing serotonin availability in the brain, gradually improving mood, sleep, and motivation over 4–6 weeks. SSRIs are not addictive, do not produce a high, and have no abuse potential — making them fundamentally different from the substances being treated.

SNRIs and bupropion

Serotonin-norepinephrine reuptake inhibitors (SNRIs) like venlafaxine (Effexor) and duloxetine (Cymbalta) target both serotonin and norepinephrine, which can be helpful for depression with prominent fatigue or chronic pain. Bupropion (Wellbutrin) is another option that acts on dopamine and norepinephrine — it can help with depression, low energy, and is also used to support smoking cessation. None of these medications carry addiction risk.

Addressing the stigma around psychiatric medication

Many people in recovery resist antidepressants because they feel taking any medication contradicts sobriety. This misconception is dangerous. Antidepressants are not mood-altering substances in the way drugs of abuse are — they restore normal brain chemistry rather than creating artificial highs. Untreated depression is one of the strongest predictors of addiction relapse. Taking prescribed, non-addictive medication to manage a medical condition is not a failure of recovery — it supports it.

Why stopping psychiatric meds leads to relapse

A common and harmful pattern occurs when people in recovery stop their antidepressants because they feel better, believe they no longer need them, or face pressure from others to be "medication-free." When depression returns — often within weeks — the emotional pain drives them back to substances. Antidepressant treatment for co-occurring depression should be maintained for at least 12 months after stabilization, and many people benefit from long-term maintenance. Any changes to psychiatric medication should be made gradually under medical supervision.

Frequently Asked Questions About Depression and Addiction

What is dual diagnosis treatment for depression and addiction?

Dual diagnosis treatment addresses both depression and substance use disorders simultaneously through integrated care. This approach recognizes that mental health and addiction affect each other and must be treated together for lasting recovery. Treatment includes psychiatric care, medication management, therapy (CBT, DBT), and specialized counseling that addresses both conditions comprehensively.

Can depression cause substance abuse?

Yes, depression significantly increases the risk of substance abuse. Many people self-medicate depression symptoms with alcohol or drugs, seeking temporary relief from emotional pain, low energy, or insomnia. However, substance use worsens depression long-term by disrupting serotonin and dopamine regulation, creating a vicious cycle. Proper treatment addresses root causes of depression while providing healthier coping strategies than substances.

Will antidepressants interfere with addiction treatment?

No, appropriate antidepressant medication actively supports recovery. Quality dual diagnosis programs work with psychiatrists to find effective antidepressant treatment while addressing addiction. Medications like SSRIs and SNRIs are non-addictive and help stabilize mood, making it easier to engage in therapy and maintain sobriety. Never stop psychiatric medications without medical guidance.

How do I find a treatment center for depression and addiction?

Look for centers explicitly offering dual diagnosis or co-occurring disorder treatment. Verify they have licensed mental health professionals, psychiatric services, medication management capabilities, and experience treating both conditions together. Use our directory to filter for dual diagnosis programs, read reviews, and verify accreditation. Contact admissions teams to discuss your specific needs.

Is residential treatment necessary for depression and addiction?

Not always. Treatment level depends on severity of both conditions, previous treatment attempts, safety concerns, and support system. Some people do well with intensive outpatient care plus medication management. Residential treatment provides 24/7 support for severe depression, suicide risk, or when outpatient treatment hasn't succeeded. A professional assessment determines the most appropriate level of care.

Can addiction cause depression or does depression cause addiction?

The relationship is bidirectional — it works both ways. Depression can lead to substance abuse through self-medication, as people use drugs or alcohol to escape emotional pain. At the same time, chronic substance use alters brain chemistry in ways that cause or worsen depression — alcohol is a central nervous system depressant, stimulant withdrawal causes profound depression, and opioid use disrupts the brain's natural mood regulation. In many cases, both conditions develop and reinforce each other simultaneously, which is why integrated dual diagnosis treatment is essential for lasting recovery.

Will I need antidepressants forever?

Not necessarily. Many people take antidepressants for 12–24 months after their mood stabilizes, then gradually taper off under medical supervision. However, some people with recurrent major depression (three or more episodes) benefit from long-term maintenance medication. The decision depends on depression severity, number of past episodes, family history, and individual response to treatment. What is critical is never stopping antidepressants abruptly — doing so can cause withdrawal symptoms and trigger relapse in both depression and addiction. Always work with your prescribing psychiatrist to make any medication changes.

Medical Review and Sources

Medically Reviewed Updated April 10, 2026

Reviewed by licensed addiction specialists. Information reflects current clinical guidance.

Sources:SAMHSA·NIDA·CDC

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