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Medically Reviewed Content
Updated: August 2026
Sources: SAMHSA, NIDA

Depression & Addiction Treatment Centers Near You

Depression and addiction frequently co-occur, requiring integrated treatment approaches. Find dual diagnosis treatment centers addressing both mental health and substance use disorders through coordinated care and evidence-based therapies.

Found 7,770 rehab centers specializing in depression across the United States.

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Find Depression and Addiction Treatment Centers Near You

Browse dual diagnosis treatment centers below. Filter for programs treating depression and substance abuse together.

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Newport Academy
Orange, CA

Newport Academy, situated in Orange, CA, stands as a premier addiction treatment facility, providing diverse, expert care. This establishment offers robust intensive outpatient services, extended residential stays, and general outpatient support for individuals struggling with substance abuse and co-occurring psychological challenges, serving both adults and younger individuals. Emphasizing customized therapeutic strategies including anger management techniques, cognitive behavioral therapy, and motivational interviewing, Newport Academy is committed to delivering thorough assistance. Its specialized offerings for teenagers, individuals who have experienced trauma, and those with dual diagnoses guarantee individualized treatment plans. Catering to a spectrum of clients, regardless of gender or age, Newport Academy is devoted to providing effective, research-backed interventions for enduring recovery.

Newport Academy
San Rafael, CA

Nestled in San Rafael, CA, Newport Academy delivers a complete spectrum of care for individuals battling substance abuse and co-occurring mental health challenges. Their offerings encompass intensive outpatient, extended residential stays, and standard outpatient services designed for adults, adolescents, and young adults. Employing proven therapeutic modalities such as cognitive behavioral therapy and motivational interviewing, the center emphasizes techniques for managing anger and incorporates trauma-informed principles. Newport Academy is particularly recognized for its specialized programs serving adolescents, individuals healing from trauma, and those facing dual diagnoses. Their gender-specific tracks for both men and women underscore a commitment to providing exceptional, personalized treatment to every individual.

Newport Beach Recovery Center

Situated in Newport Beach, CA, the Newport Beach Recovery Center provides extensive services for the treatment of addiction aimed at adults and young adults. This center focuses on detoxification along with substance use rehabilitation, offering both long-term residential treatment and detox services. The facility employs a range of therapeutic techniques, including 12-step programs, anger management, and brief intervention. It also features specialized programs for active duty military members, as well as distinct services for adult men and women, ensuring a tailored approach to care. By providing separate tracks for male and female clients, the center emphasizes personalized treatment. The Newport Beach Recovery Center is committed to offering evidence-based, high-quality care to foster sustained recovery.

Newport Institute
Santa Ana, CA

Newport Institute, situated in Santa Ana, CA, provides extensive addiction treatment and focused support for individuals of all ages experiencing dual diagnoses. This center features various levels of care, including intensive outpatient, extended residential stays, and standard outpatient options, all designed with personalized treatment plans. Their therapeutic interventions encompass anger management techniques, cognitive behavioral therapy, and strategies for preventing relapse. Newport Institute also distinguishes itself with specialized offerings for LGBTQ+ individuals, trauma survivors, and those with co-occurring mental health issues. Catering to adults and young adults, irrespective of gender, Newport Institute is committed to offering superior, personalized care aimed at achieving enduring recovery and overall well-being.

Newport Institute
Temecula, CA

Situated in Temecula, CA, Newport Institute provides an extensive range of substance use rehabilitation services for both adults and young adults facing concurrent mental health issues. The facility offers various treatment options, including intensive outpatient programs, long-term residential care, and outpatient services. Utilizing evidence-based methods such as anger management, cognitive behavioral therapy, and motivational interviewing, Newport Institute distinguishes itself with specialized programs for trauma survivors, individuals with dual diagnoses, and members of the LGBTQ community. The center fosters a secure and welcoming atmosphere, delivering personalized treatment for all clients, regardless of gender, to support their journey to recovery.

Newport Institute
Santa Ana, CA

Situated in Santa Ana, CA, Newport Institute delivers extensive rehabilitation services aimed at adults and young adults facing challenges related to substance use disorders and concurrent mental health conditions. The center provides various treatment modalities, such as intensive outpatient programs, long-term residential care, and outpatient services. Specialized therapies offered include anger management, cognitive behavioral therapy, and strategies for relapse prevention. Newport Institute is distinguished by its commitment to trauma-informed care, programs that affirm LGBTQ identities, and customized services for those with dual diagnoses. With support available for both males and females, this facility prioritizes individualized, high-quality care to facilitate enduring recovery.

Newport Institute

Situated in Orange, CA, Newport Institute provides thorough treatment for substance use issues in adults and young adults facing simultaneous mental health challenges. The center offers various programs, including intensive outpatient, long-term residential, and outpatient care, all grounded in proven methods such as cognitive behavioral therapy and motivational interviewing. Specialized programs are available for LGBTQ individuals and survivors of trauma. Emphasizing anger management and tailored support, Newport Institute creates a nurturing space for those on their recovery journey. Catering to both male and female clients, this facility is dedicated to delivering high-quality care for a wide spectrum of individuals aiming to conquer addiction and mental health difficulties.

Newport Institute
Santa Ana, CA

Newport Institute, situated in Santa Ana, CA, provides extensive programs for substance abuse and dedicated support for individuals facing co-occurring mental health challenges and children with significant emotional difficulties. Their range of services encompasses intensive outpatient, extended residential stays, and standard outpatient options. Employing proven therapeutic methods like cognitive behavioral therapy, motivational interviewing, and relapse prevention strategies, the facility offers personalized assistance to clients with trauma backgrounds, dual diagnoses, and those within the LGBTQ community. Newport Institute serves adults and young adults of all genders, committed to delivering superior care and customized treatment strategies to address every client's distinct requirements.

Newport Institute

Nestled in Sunol, California, Newport Institute is dedicated to providing tailored recovery programs for adults and young adults grappling with addiction and associated mental health issues. The center offers a spectrum of care, including intensive outpatient, extended residential stays, and standard outpatient services. Employing scientifically validated methods such as cognitive behavioral therapy and motivational interviewing, Newport Institute emphasizes strategies for preventing relapse and personalizing the recovery journey. Their offerings are designed to support individuals who have faced trauma, those with dual diagnoses, and members of the LGBTQ+ community. Committed to high standards of care, Newport Institute supports both male and female clients on their path to enduring sobriety.

Nexstep Medical Detox

Nexstep Medical Detox, situated in Orem, UT, delivers thorough substance withdrawal and addiction treatment within a hospital inpatient environment. This facility specializes in care that includes 12-step support, addiction counseling, and remote therapy options. Nexstep offers customized treatment for active military personnel, adult men, and adult women, accommodating both adult and young adult individuals. Their programs are designed with gender-specific approaches for men and women. Clients can anticipate excellent care and assistance throughout their path to healing at Nexstep.

Next Door Inc
Nashville, TN

Next Door Inc, located in Nashville, TN, is dedicated to providing specialized recovery programs for adult women facing addiction. They offer comprehensive treatment pathways, including intensive outpatient care, day treatment programs, and partial hospitalization. Employing proven therapeutic methods like 12-step support, anger management techniques, and brief intervention strategies, Next Door Inc effectively addresses the complex needs of individuals with dual diagnoses of mental health and substance use disorders. The center emphasizes a trauma-informed approach, fostering a secure and encouraging atmosphere for adults, seniors, and young adults committed to their sobriety journey. Next Door Inc distinguishes itself through personalized treatment plans and a steadfast dedication to high-quality support for those seeking lasting recovery.

Next Level Recovery

Situated in Midvale, UT, Next Level Recovery provides an extensive array of rehabilitation services. This center focuses on detoxification, addiction treatment, and tailored support for individuals dealing with both substance use issues and significant mental health disorders. The treatment options available include intensive outpatient programs, outpatient services, and partial hospitalization. Next Level Recovery employs proven methods such as 12-step programs, anger management strategies, and brief counseling sessions. The facility also offers specialized programs designed for active duty military members, adolescents, and adult males, accommodating a wide spectrum of clients. Catering to both adults and youth, Next Level Recovery prioritizes personalized care for all clients, offering high-quality support for those aiming to conquer addiction and mental health difficulties.

Next Step Foundation Inc

Next Step Foundation Inc., located in Terre Haute, IN, provides tailored programs for adults and children facing substance use challenges and co-occurring mental health conditions. Their approach encompasses intensive outpatient, long-term residential, and standard outpatient services, all designed with individual needs in mind. Therapeutic interventions include 12-step facilitation, cognitive behavioral therapy, and motivational interviewing. The center features distinct programs for adult men, adult women, and individuals affected by domestic abuse. Next Step Foundation Inc. is committed to offering inclusive, high-quality care for adults and young adults, promoting a holistic journey to recovery and sustained well-being.

Newton Medical Center

Newton Medical Center, located in Newton, NJ, provides extensive outpatient care for individuals dealing with substance use disorders, concurrent mental health conditions, and emotional challenges. The center features targeted programs designed for adult men, women, and clients facing dual diagnoses. Treatment options encompass 12-step support, brief interventions, and cognitive behavioral therapy, customized for both adult and adolescent clients of any gender. With options for outpatient day programs and methadone/buprenorphine treatments, the facility prioritizes tailored care meeting the distinct requirements of each individual. Newton Medical Center is distinguished by its commitment to evidence-based practices and high standards of personalized rehabilitation services.

Newport Integrated

Newport Integrated, situated in Decatur, GA, delivers thorough care for those confronting addiction and accompanying mental health challenges. Their inpatient detox and treatment options are available for adults and seniors, featuring distinct programs for active military personnel, teenagers, and adult men. The facility utilizes scientifically-backed methods such as 12-step facilitation, anger management techniques, and brief therapeutic interventions. Committed to high standards of care, Newport Integrated fosters a nurturing atmosphere for all clients, regardless of gender, on their journey to recovery. For tailored and successful addiction treatment, this establishment is devoted to guiding you toward sustained abstinence.

Newport Academy
Kirkland, WA

Nestled in Kirkland, WA, Newport Academy provides complete care for individuals, including young people, battling addiction and co-occurring mental health conditions. They offer various levels of support, from intensive outpatient and extended residential stays to standard outpatient services, with a focus on strategies like anger management, cognitive behavioral therapy, and motivational interviewing. Specialized offerings are available for teenagers, those with trauma histories, and clients facing dual diagnoses. Newport Academy welcomes male and female patients of all ages, delivering personalized treatment grounded in proven methods to foster sustained recovery. For superior rehabilitation in the Kirkland region, Newport Academy is committed to guiding you toward enduring well-being.

Newport Mental Health
Middletown, RI

Newport Mental Health, situated in Middletown, RI, delivers targeted outpatient care for individuals dealing with substance abuse as well as accompanying mental health issues among both adults and youth. The facility offers a variety of services such as outpatient methadone/buprenorphine or naltrexone treatment, anger management, brief intervention, and cognitive behavioral therapy. It is particularly focused on assisting trauma survivors and those with dual diagnoses, providing care for both male and female patients in a nurturing setting. Whether needing support for substance use, significant mental health challenges, or emotional issues, Newport Mental Health presents extensive programs designed to address unique requirements and foster enduring recovery.

Newport Mental Health
Middletown, RI

Newport Mental Health, situated in Middletown, RI, delivers an extensive variety of outpatient services aimed at addressing substance use and concurrent mental health challenges for both adults and children. The center specializes in various therapeutic approaches, including anger management, cognitive behavioral therapy, and trauma-informed care. Committed to providing high-quality support, Newport Mental Health customizes treatment strategies to cater to the unique requirements of each client, particularly those facing both mental health and substance use issues. The facility accommodates adults and young adults, offering treatment options that are specific to gender. Whether in need of routine outpatient services or medication-assisted treatments like methadone or buprenorphine, clients can expect individualized support and care at Newport Mental Health.

Newport Mental Health
Middletown, RI

Newport Mental Health, situated in Middletown, RI, delivers extensive outpatient care for addiction and co-occurring psychological issues. The facility offers dedicated support for adults and young individuals experiencing significant emotional distress. Therapeutic methods employed encompass anger resolution, timely interventions, and cognitive-behavioral strategies. Distinct programs are available for teenagers, survivors of trauma, and those with integrated mental health and substance abuse challenges. Committed to high standards, Newport Mental Health crafts individualized recovery paths for all genders.

Next Step Treatment Center

Next Step Treatment Center, situated in Baltimore, Maryland, focuses on providing tailored substance use treatment for adult clients who also grapple with significant mental health disorders. This center features both intensive outpatient and outpatient services, incorporating treatment options such as methadone and buprenorphine. Emphasizing approaches like 12-step facilitation, anger management, and brief intervention, it serves both men and women, including senior adult clients. Additionally, specialized programs are designed for adolescents, adult males, and adult females. Committed to offering exceptional care, Next Step Treatment Center aims to support individuals in advancing towards their recovery journey.

Depression & Substance Use Disorder: Key Facts

Classification

Major Depressive Disorder + Substance Use Disorder (Dual Diagnosis)

Co-occurrence

~1 in 3 people with depression also have SUD (NIDA)

Prevalence

21 million adults with major depressive episode/year (NIMH)

Self-medication

Depression is the #1 reason for substance self-medication

Treatment approach

Integrated dual diagnosis (treat both simultaneously)

Key therapies

CBT, DBT, medication management, group therapy

Medications

SSRIs (non-addictive), SNRIs — safe during addiction treatment

Prognosis

Significantly better outcomes with integrated treatment vs sequential

If you or someone you know is experiencing suicidal thoughts, call 988 (Suicide & Crisis Lifeline) or text 988 immediately. Help is available 24/7.

Depression and Addiction: The Dual Diagnosis Connection

How depression and addiction feed each other

Depression and substance use disorder share a deeply intertwined relationship. Depression causes persistent feelings of emptiness, hopelessness, and emotional pain that drive many people toward alcohol or drugs as a form of self-medication. Substances may provide temporary relief, but they alter brain chemistry in ways that worsen depressive symptoms over time — creating a destructive cycle that accelerates both conditions.

The self-medication cycle

The self-medication cycle is the most common pathway from depression to addiction. A person experiencing persistent sadness, fatigue, or emotional numbness turns to alcohol, opioids, or stimulants to feel better temporarily. As tolerance builds, they need more of the substance to achieve the same relief. Meanwhile, the substance disrupts serotonin and dopamine regulation in the brain, deepening the depression. When the substance wears off, the depression returns worse than before — driving further substance use.

Why treating one without the other fails

Treating addiction without addressing underlying depression leaves the root cause intact. The person achieves sobriety but continues suffering from untreated depression, making relapse nearly inevitable as they seek relief. Conversely, treating depression without addressing active substance use is ineffective because ongoing drug or alcohol use undermines the neurochemical changes that antidepressants and therapy work to achieve. This is why dual diagnosis treatment — addressing both conditions simultaneously — produces significantly better outcomes than treating either condition alone.

Signs of Co-Occurring Depression and Substance Abuse

Recognizing co-occurring depression and substance abuse can be challenging because symptoms overlap. Watch for these warning signs:

Emotional and behavioral signs

  • Persistent sadness combined with increased substance use
  • Withdrawal from friends, family, and activities once enjoyed
  • Using drugs or alcohol specifically to cope with emptiness or hopelessness
  • Feelings of worthlessness or excessive guilt alongside substance use
  • Loss of motivation or interest in recovery efforts

Physical signs

  • Significant changes in sleep patterns — insomnia or oversleeping
  • Appetite and weight changes (loss or gain)
  • Chronic fatigue even with adequate rest
  • Increased substance tolerance requiring higher doses
  • Neglect of personal hygiene and self-care

How Dual Diagnosis Treatment Works

Integrated approach

Dual diagnosis treatment treats depression and addiction as interconnected conditions rather than separate problems. Instead of completing addiction treatment first and then addressing depression (the sequential approach that often fails), integrated programs work on both simultaneously. This means therapy sessions address how depressive thoughts drive substance use, while psychiatric care stabilizes mood to support sobriety.

Psychiatric evaluation during early sobriety

Accurate diagnosis of depression requires evaluation during a period of sobriety, because many substances can mimic or mask depressive symptoms. Alcohol is a depressant that causes sadness and lethargy. Stimulant withdrawal causes profound depression. A psychiatrist experienced in dual diagnosis will conduct thorough assessments during early sobriety to distinguish substance-induced mood changes from underlying major depressive disorder, ensuring the right treatment plan.

Coordinated care teams

Effective dual diagnosis programs use coordinated care teams where psychiatrists, addiction counselors, therapists, and medical staff communicate about each patient's progress. The psychiatrist managing antidepressant medication works closely with the addiction counselor guiding recovery, so treatment decisions account for both conditions. This prevents the common problem of one provider unknowingly undermining another's treatment plan.

Medication management alongside addiction treatment

One of the most important aspects of dual diagnosis care is safe medication management. Antidepressants like SSRIs and SNRIs are non-addictive and can be prescribed safely during addiction treatment. A psychiatrist monitors medication effectiveness, adjusts dosages, and watches for interactions — all while the person is actively working on recovery from substance use disorder.

Evidence-Based Therapies for Depression in Recovery

Cognitive Behavioral Therapy (CBT)

Cognitive Behavioral Therapy (CBT) is the gold standard for treating co-occurring depression and addiction. CBT helps identify negative thought patterns that drive both depressive episodes and substance use — such as "nothing will ever get better" or "I can't cope without drinking." Patients learn to challenge these distortions and replace them with realistic, constructive thinking. Research consistently shows CBT reduces both depressive symptoms and substance use relapse rates.

Dialectical Behavior Therapy (DBT)

Dialectical Behavior Therapy (DBT) is particularly effective for people with severe depression, emotional dysregulation, or self-harm behaviors alongside addiction. DBT teaches four core skill sets: mindfulness, distress tolerance, emotion regulation, and interpersonal effectiveness. These skills directly address the emotional pain that drives self-medication and provide healthier alternatives to substance use.

Group therapy

Group therapy combats the isolation that is central to both depression and addiction. Hearing others share similar struggles reduces shame and hopelessness. Dual diagnosis groups specifically address how depression and substance use interact, offering peer support from people who understand both conditions. Group settings also build social skills and accountability that support long-term recovery.

Medication management

Antidepressant medications are a critical component of treatment for many people with co-occurring depression and addiction. SSRIs (selective serotonin reuptake inhibitors) like sertraline and fluoxetine are first-line treatments because they are effective, well-tolerated, and — importantly — non-addictive. They carry no abuse potential and do not produce euphoria, making them safe to prescribe during addiction recovery. SNRIs like venlafaxine and duloxetine are also effective alternatives.

Levels of Care for Depression and Addiction

When residential treatment is needed

Residential treatment is recommended when depression is severe — particularly when suicidal ideation is present, when the person has made previous suicide attempts, or when outpatient treatment has failed. Residential programs provide 24/7 psychiatric monitoring, immediate medication adjustments, and a safe environment removed from triggers. People with severe addiction alongside major depression often need this level of structured support to stabilize both conditions.

Intensive Outpatient Programs (IOP)

Intensive Outpatient Programs provide 9–20 hours of structured therapy per week while allowing patients to live at home. IOP is appropriate for moderate depression with addiction, for people stepping down from residential care, or when the person has a stable living environment and support system. Dual diagnosis IOP programs include both addiction counseling and psychiatric services.

Outpatient care with medication management

Standard outpatient treatment works well for mild to moderate depression with substance use disorder, especially when combined with antidepressant medication. This typically involves weekly therapy sessions, regular psychiatric check-ins for medication management, and support group participation. Outpatient care allows people to maintain work, family, and daily responsibilities while receiving treatment.

Choosing the right level of care

The appropriate level of care depends on several factors: severity of depression (mild vs. severe with suicidal thoughts), severity of addiction, previous treatment attempts and outcomes, strength of social support, co-occurring medical conditions, and safety concerns. A professional assessment by a dual diagnosis specialist can determine the best starting point. Many people move through multiple levels of care as they progress in recovery.

Antidepressant Medications in Recovery

SSRIs: the first-line treatment

Selective serotonin reuptake inhibitors (SSRIs) such as sertraline (Zoloft), fluoxetine (Prozac), and escitalopram (Lexapro) are the most commonly prescribed antidepressants for people in addiction recovery. They work by increasing serotonin availability in the brain, gradually improving mood, sleep, and motivation over 4–6 weeks. SSRIs are not addictive, do not produce a high, and have no abuse potential — making them fundamentally different from the substances being treated.

SNRIs and bupropion

Serotonin-norepinephrine reuptake inhibitors (SNRIs) like venlafaxine (Effexor) and duloxetine (Cymbalta) target both serotonin and norepinephrine, which can be helpful for depression with prominent fatigue or chronic pain. Bupropion (Wellbutrin) is another option that acts on dopamine and norepinephrine — it can help with depression, low energy, and is also used to support smoking cessation. None of these medications carry addiction risk.

Addressing the stigma around psychiatric medication

Many people in recovery resist antidepressants because they feel taking any medication contradicts sobriety. This misconception is dangerous. Antidepressants are not mood-altering substances in the way drugs of abuse are — they restore normal brain chemistry rather than creating artificial highs. Untreated depression is one of the strongest predictors of addiction relapse. Taking prescribed, non-addictive medication to manage a medical condition is not a failure of recovery — it supports it.

Why stopping psychiatric meds leads to relapse

A common and harmful pattern occurs when people in recovery stop their antidepressants because they feel better, believe they no longer need them, or face pressure from others to be "medication-free." When depression returns — often within weeks — the emotional pain drives them back to substances. Antidepressant treatment for co-occurring depression should be maintained for at least 12 months after stabilization, and many people benefit from long-term maintenance. Any changes to psychiatric medication should be made gradually under medical supervision.

Frequently Asked Questions About Depression and Addiction

What is dual diagnosis treatment for depression and addiction?

Dual diagnosis treatment addresses both depression and substance use disorders simultaneously through integrated care. This approach recognizes that mental health and addiction affect each other and must be treated together for lasting recovery. Treatment includes psychiatric care, medication management, therapy (CBT, DBT), and specialized counseling that addresses both conditions comprehensively.

Can depression cause substance abuse?

Yes, depression significantly increases the risk of substance abuse. Many people self-medicate depression symptoms with alcohol or drugs, seeking temporary relief from emotional pain, low energy, or insomnia. However, substance use worsens depression long-term by disrupting serotonin and dopamine regulation, creating a vicious cycle. Proper treatment addresses root causes of depression while providing healthier coping strategies than substances.

Will antidepressants interfere with addiction treatment?

No, appropriate antidepressant medication actively supports recovery. Quality dual diagnosis programs work with psychiatrists to find effective antidepressant treatment while addressing addiction. Medications like SSRIs and SNRIs are non-addictive and help stabilize mood, making it easier to engage in therapy and maintain sobriety. Never stop psychiatric medications without medical guidance.

How do I find a treatment center for depression and addiction?

Look for centers explicitly offering dual diagnosis or co-occurring disorder treatment. Verify they have licensed mental health professionals, psychiatric services, medication management capabilities, and experience treating both conditions together. Use our directory to filter for dual diagnosis programs, read reviews, and verify accreditation. Contact admissions teams to discuss your specific needs.

Is residential treatment necessary for depression and addiction?

Not always. Treatment level depends on severity of both conditions, previous treatment attempts, safety concerns, and support system. Some people do well with intensive outpatient care plus medication management. Residential treatment provides 24/7 support for severe depression, suicide risk, or when outpatient treatment hasn't succeeded. A professional assessment determines the most appropriate level of care.

Can addiction cause depression or does depression cause addiction?

The relationship is bidirectional — it works both ways. Depression can lead to substance abuse through self-medication, as people use drugs or alcohol to escape emotional pain. At the same time, chronic substance use alters brain chemistry in ways that cause or worsen depression — alcohol is a central nervous system depressant, stimulant withdrawal causes profound depression, and opioid use disrupts the brain's natural mood regulation. In many cases, both conditions develop and reinforce each other simultaneously, which is why integrated dual diagnosis treatment is essential for lasting recovery.

Will I need antidepressants forever?

Not necessarily. Many people take antidepressants for 12–24 months after their mood stabilizes, then gradually taper off under medical supervision. However, some people with recurrent major depression (three or more episodes) benefit from long-term maintenance medication. The decision depends on depression severity, number of past episodes, family history, and individual response to treatment. What is critical is never stopping antidepressants abruptly — doing so can cause withdrawal symptoms and trigger relapse in both depression and addiction. Always work with your prescribing psychiatrist to make any medication changes.

Medical Review and Sources

Medically Reviewed Updated April 10, 2026

Reviewed by licensed addiction specialists. Information reflects current clinical guidance.

Sources:SAMHSA·NIDA·CDC

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