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Medically Reviewed Content
Updated: August 2026
Sources: SAMHSA, NIDA

Depression & Addiction Treatment Centers Near You

Depression and addiction frequently co-occur, requiring integrated treatment approaches. Find dual diagnosis treatment centers addressing both mental health and substance use disorders through coordinated care and evidence-based therapies.

Found 7,770 rehab centers specializing in depression across the United States.

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Find Depression and Addiction Treatment Centers Near You

Browse dual diagnosis treatment centers below. Filter for programs treating depression and substance abuse together.

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Quinault Indian Nation

Nestled in Taholah, WA, the Quinault Indian Nation treatment facility delivers comprehensive programs for individuals of all ages struggling with addiction and dual diagnoses. Their services include intensive outpatient, outpatient, and standard outpatient care, employing therapeutic methods like anger management, brief intervention, and cognitive behavioral therapy. Dedicated tracks are available for teens, adult men, and adult women, ensuring personalized support. Serving adults and older adults of all genders, the Quinault Indian Nation facility is committed to providing excellent care and tailored interventions to foster healing and overall wellness.

R and R Recovery
Huntington Beach, CA

R and R Recovery in Huntington Beach, CA, delivers a complete spectrum of care for individuals struggling with addiction. They offer intensive outpatient, standard outpatient, and partial hospitalization programs. Their therapeutic methods include anger management, cognitive behavioral therapy, and the Matrix Model, addressing the needs of those with co-occurring mental health and substance use issues, as well as individuals with histories of sexual abuse or trauma. Tailored programs for men and women are available, reflecting R and R Recovery's commitment to personalized, high-quality support for sustained sobriety.

Rainbow Hill Recovery
Los Angeles, CA

Rainbow Hill Recovery, located in Los Angeles, CA, specializes in addressing substance abuse and co-occurring mental health issues for both adults and children. The center offers a variety of outpatient and day treatment programs, incorporating 12-step support, anger management, and short-term intervention strategies. They have distinctive programs designed for active duty military members, as well as tailored services for adult men and women. By providing high-quality care within a nurturing setting, Rainbow Hill Recovery effectively supports adults and young adults of all genders. Whether individuals are looking for intensive outpatient services or partial hospitalization, they receive customized care to facilitate their recovery process.

Rainbows End Recovery Center LLC

Rainbows End Recovery Center LLC in Challis, ID, provides comprehensive treatment for addiction and co-occurring mental health issues. They offer various levels of care, including intensive outpatient, long-term residential, and standard outpatient programs. Their therapeutic interventions incorporate proven methods like 12-step facilitation, anger management, and cognitive behavioral therapy. The center has specialized programs designed for adult men and women, as well as survivors of intimate partner violence or domestic abuse. Serving adults and young adults across the gender spectrum, Rainbows End Recovery Center LLC is dedicated to supporting individuals on their journey to recovery.

Raleigh House of Hope

Situated in Watkins, CO, the Raleigh House of Hope delivers an extensive array of addiction recovery services for both adults and young adults. The center features inpatient detox programs and provides round-the-clock medical care. Emphasizing 12-step methodologies, anger management strategies, and brief intervention tactics, this facility serves adult men and women, including individuals who have faced sexual trauma. With options for transitional living and halfway housing, the Raleigh House of Hope prioritizes personalized treatment for all clients. Committed to high standards and customized recovery plans, this center fosters a nurturing atmosphere for individuals aiming to overcome substance use challenges.

Ralph H Johnson VA Medical Center

The Ralph H Johnson VA Medical Center, located in Charleston, SC, provides an extensive array of rehabilitation services tailored for adults and seniors facing challenges related to substance abuse and concurrent mental health disorders. Their offerings encompass inpatient detoxification within a hospital setting, intensive outpatient care, and round-the-clock inpatient services. This facility is particularly skilled in techniques such as anger management, brief interventions, and cognitive behavioral therapy. Additionally, specialized programs are available for adult men and women, as well as for individuals who have suffered from intimate partner violence or domestic abuse. Emphasizing personalized care, the center fosters a secure and encouraging atmosphere for all patients pursuing effective recovery from addiction.

RAM Recovery LLC
Waldorf, MD

RAM Recovery LLC, located in Waldorf, MD, delivers a wide range of substance abuse treatment options, including intensive outpatient programs, outpatient services, and medication-assisted therapies such as methadone/buprenorphine or naltrexone. The center employs techniques like 12-step facilitation, anger management, and cognitive behavioral therapy, aiming to support adult men and women, including those who have suffered from intimate partner or domestic violence. With a specialization in care for adults and young adults, RAM Recovery LLC offers personalized treatment plans tailored to the needs of both male and female clients. Committed to high-quality care and evidence-based practices, it stands out as a reliable option for those seeking rehabilitation in the Waldorf community.

Radius Health
Saint Paul, MN

Radius Health, situated in Saint Paul, MN, provides extensive rehabilitation care. The center focuses on addiction recovery, supportive living arrangements, and integrated treatment for dual diagnoses involving mental health and substance use in both younger and older individuals. Employing outpatient and intensive outpatient options, the facility uses proven therapeutic techniques including anger management, cognitive behavioral therapy, and the Matrix Model. Radius Health offers distinct programs for active military members, teenagers, adult men, and individualized support for adult men and women, including seniors. Discover excellent care and successful recovery at Radius Health.

Quil Ceda Creek Counseling Company

Quil Ceda Creek Counseling Company in Marysville, WA, delivers a complete suite of services for individuals of all ages struggling with addiction and concurrent mental health conditions. They offer various levels of care including intensive outpatient, standard outpatient, and medication-assisted treatment using methadone, buprenorphine, or naltrexone. The facility employs evidence-based strategies like cognitive behavioral therapy, motivational interviewing, and contingency management, customizing treatment plans for each person. Specialized support is available for adult women, those with dual diagnoses, and individuals involved in the criminal justice system. This center is dedicated to providing effective and compassionate recovery assistance to adults and young adults.

Ram Recovery
Baltimore, MD

Situated in Baltimore, MD, Ram Recovery specializes in delivering tailored substance use treatment services for both adults and young adults. The facility offers various options including intensive outpatient, outpatient, and treatments with methadone, buprenorphine, or naltrexone. Emphasizing a 12-step approach, along with strategies such as anger management and cognitive behavioral therapy, Ram Recovery customizes its methods to fit the unique requirements of each client. The center takes pride in offering distinctive programs designed for adult men, adult women, and individuals affected by intimate partner or domestic violence. Catering to both genders, Ram Recovery aims to create an all-encompassing and nurturing atmosphere for those pursuing recovery from addiction.

Ramey Estep Homes

Ramey Estep Homes, located in Rush, KY, provides exceptional treatment for substance use disorders along with focused care for adults facing co-occurring substance use and serious mental health challenges, as well as emotional issues in children. The center features various program lengths, including long-term, short-term, and 24-hour residential options, implementing evidence-based practices like 12-step facilitation, anger management, and cognitive behavioral therapy. Ramey Estep Homes is particularly noted for its customized programs catering to adult men and women, those who have suffered from domestic or intimate partner violence, and services designed for all genders among adults and young adults. The center is dedicated to offering high-quality support to assist individuals in their recovery process.

Raise the Bottom Training and

Raise the Bottom Training and provides thorough outpatient care for addiction in Boise, ID. This center focuses on addressing dual diagnoses, treating substance use disorders concurrently with significant mental health conditions in adults and severe emotional challenges in youth. Employing therapeutic methods such as anger management, cognitive behavioral therapy, and brief intervention strategies, the facility customizes its programs to suit each person's unique requirements. Specialized offerings exist for active military members, adult men, and women. Catering to adults and young adults irrespective of gender, Raise the Bottom Training and delivers high-caliber services including outpatient care, medication-assisted treatment (methadone/buprenorphine or naltrexone), and standard outpatient support.

Ramey Estep Homes/ReGroup

At Ramey Estep Homes/ReGroup in Ashland, KY, individuals find a complete approach to overcoming addiction and addressing complex mental health needs. This center specializes in treating co-occurring substance use and serious mental health issues in adults, alongside significant emotional challenges in children. They offer flexible treatment options like intensive outpatient, outpatient, and day treatment programs, all customized to individual needs. Therapies employed include anger management, cognitive behavioral therapy, and the evidence-based Matrix Model. Separate programs are available for adolescents, adult men, and adult women. Ramey Estep Homes/ReGroup provides supportive, high-quality care to adults and seniors of all genders within a nurturing setting.

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Situated in Dayville, CT, the Quinebaug Day Treatment Program provides a full spectrum of care for those pursuing recovery from addiction, mental health challenges, and the complexities of co-occurring disorders. Its offerings encompass intensive outpatient and partial hospitalization programs, designed to serve both adolescents and adults. The center features tailored interventions for young adults and individuals facing dual diagnoses. Employing strategies like 12-step integration and anger management techniques, Quinebaug Day Treatment Program is dedicated to offering exceptional support to all its male and female patients. This facility represents a significant resource for effective recovery and well-being.

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Railbelt Mental Health and Addictions, situated in Anderson, AK, specializes in outpatient services for substance use disorders and addresses co-occurring disorders related to severe mental health issues in adults, as well as significant emotional challenges in children. The center employs a variety of treatment methods, including cognitive behavioral therapy, brief interventions, and anger management, to deliver effective outpatient care. It features targeted programs for active duty service members, teenagers, and adult males, offering support to individuals of all ages and genders. Patients can look forward to tailored treatment plans and exceptional care that aids in their recovery journey.

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Railbelt Mental Health and Addictions, located in Nenana, AK, specializes in outpatient treatment for adults dealing with substance use and significant co-occurring mental health disorders. The center offers a variety of regular outpatient services, incorporating methods such as cognitive behavioral therapy, brief interventions, and anger management strategies. It features targeted programs for different populations, including active military personnel, teenagers, and adult men, ensuring a wide range of support options for various demographics. Known for its high-quality care, this facility distinguishes itself through its extensive treatment offerings and customized programs aimed at effectively meeting individual needs. If you are in search of an addiction treatment facility that emphasizes a supportive atmosphere, Railbelt Mental Health and Addictions provides individualized, evidence-informed care.

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At its Highland Park, MI location, Rainbow Center of Michigan Inc. provides comprehensive outpatient services for detoxification and substance use disorders. The center excels in utilizing methodologies such as 12-step facilitation, anger management, and cognitive behavioral therapy. Dedicated to assisting adult men and women, including survivors of intimate partner and domestic violence, Rainbow Center of Michigan Inc. delivers personalized treatment plans. The facility also extends its specialized care to young adults, offering distinct gender-specific programs for both men and women, ensuring a high standard of individualized support for all clients in their recovery process.

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Rainforest Recovery Center, situated in Juneau, AK, delivers outpatient care for adults and young adults battling substance misuse. Their focus is on assisting individuals who are simultaneously experiencing substance use disorders and significant mental health challenges. The center offers diverse treatment options, including medication-assisted treatment with methadone, buprenorphine, or naltrexone, alongside general outpatient services. Employing proven therapeutic methods like cognitive behavioral therapy and motivational incentives, Rainforest Recovery Center is committed to providing exceptional support. They have developed specialized services for those with dual diagnoses of mental health and substance use conditions, serving both men and women in their journey toward recovery.

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Nestled in Nampa, ID, Raise the Bottom Training and is dedicated to providing outpatient substance use disorder services for adults and adolescents facing co-occurring mental health conditions. The center offers medication-assisted treatment with methadone, buprenorphine, or naltrexone, alongside general outpatient care. Therapeutic modalities employed include anger management, brief intervention strategies, and cognitive behavioral therapy. Specialized support is available for active military personnel, adult men, and adult women, ensuring a broad spectrum of needs are met. Raise the Bottom Training and extends its comprehensive, supportive, and professional treatment options to adults and young adults, fostering a compassionate environment for recovery.

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Situated in Pocatello, ID, Raise the Bottom Training is dedicated to providing outpatient support for adults struggling with substance use disorders. They also address co-occurring mental health and substance use issues in both adult and pediatric populations. The facility offers medication-assisted treatment options such as methadone, buprenorphine, or naltrexone, alongside general outpatient services. Specific programs are available for active-duty military personnel, as well as men and women. Therapeutic interventions employed include anger management techniques, brief intervention strategies, and cognitive behavioral therapy. Serving a diverse clientele of adults and young adults, Raise the Bottom Training prioritizes effective, high-quality care to aid individuals in their recovery from addiction and mental health concerns.

Depression & Substance Use Disorder: Key Facts

Classification

Major Depressive Disorder + Substance Use Disorder (Dual Diagnosis)

Co-occurrence

~1 in 3 people with depression also have SUD (NIDA)

Prevalence

21 million adults with major depressive episode/year (NIMH)

Self-medication

Depression is the #1 reason for substance self-medication

Treatment approach

Integrated dual diagnosis (treat both simultaneously)

Key therapies

CBT, DBT, medication management, group therapy

Medications

SSRIs (non-addictive), SNRIs — safe during addiction treatment

Prognosis

Significantly better outcomes with integrated treatment vs sequential

If you or someone you know is experiencing suicidal thoughts, call 988 (Suicide & Crisis Lifeline) or text 988 immediately. Help is available 24/7.

Depression and Addiction: The Dual Diagnosis Connection

How depression and addiction feed each other

Depression and substance use disorder share a deeply intertwined relationship. Depression causes persistent feelings of emptiness, hopelessness, and emotional pain that drive many people toward alcohol or drugs as a form of self-medication. Substances may provide temporary relief, but they alter brain chemistry in ways that worsen depressive symptoms over time — creating a destructive cycle that accelerates both conditions.

The self-medication cycle

The self-medication cycle is the most common pathway from depression to addiction. A person experiencing persistent sadness, fatigue, or emotional numbness turns to alcohol, opioids, or stimulants to feel better temporarily. As tolerance builds, they need more of the substance to achieve the same relief. Meanwhile, the substance disrupts serotonin and dopamine regulation in the brain, deepening the depression. When the substance wears off, the depression returns worse than before — driving further substance use.

Why treating one without the other fails

Treating addiction without addressing underlying depression leaves the root cause intact. The person achieves sobriety but continues suffering from untreated depression, making relapse nearly inevitable as they seek relief. Conversely, treating depression without addressing active substance use is ineffective because ongoing drug or alcohol use undermines the neurochemical changes that antidepressants and therapy work to achieve. This is why dual diagnosis treatment — addressing both conditions simultaneously — produces significantly better outcomes than treating either condition alone.

Signs of Co-Occurring Depression and Substance Abuse

Recognizing co-occurring depression and substance abuse can be challenging because symptoms overlap. Watch for these warning signs:

Emotional and behavioral signs

  • Persistent sadness combined with increased substance use
  • Withdrawal from friends, family, and activities once enjoyed
  • Using drugs or alcohol specifically to cope with emptiness or hopelessness
  • Feelings of worthlessness or excessive guilt alongside substance use
  • Loss of motivation or interest in recovery efforts

Physical signs

  • Significant changes in sleep patterns — insomnia or oversleeping
  • Appetite and weight changes (loss or gain)
  • Chronic fatigue even with adequate rest
  • Increased substance tolerance requiring higher doses
  • Neglect of personal hygiene and self-care

How Dual Diagnosis Treatment Works

Integrated approach

Dual diagnosis treatment treats depression and addiction as interconnected conditions rather than separate problems. Instead of completing addiction treatment first and then addressing depression (the sequential approach that often fails), integrated programs work on both simultaneously. This means therapy sessions address how depressive thoughts drive substance use, while psychiatric care stabilizes mood to support sobriety.

Psychiatric evaluation during early sobriety

Accurate diagnosis of depression requires evaluation during a period of sobriety, because many substances can mimic or mask depressive symptoms. Alcohol is a depressant that causes sadness and lethargy. Stimulant withdrawal causes profound depression. A psychiatrist experienced in dual diagnosis will conduct thorough assessments during early sobriety to distinguish substance-induced mood changes from underlying major depressive disorder, ensuring the right treatment plan.

Coordinated care teams

Effective dual diagnosis programs use coordinated care teams where psychiatrists, addiction counselors, therapists, and medical staff communicate about each patient's progress. The psychiatrist managing antidepressant medication works closely with the addiction counselor guiding recovery, so treatment decisions account for both conditions. This prevents the common problem of one provider unknowingly undermining another's treatment plan.

Medication management alongside addiction treatment

One of the most important aspects of dual diagnosis care is safe medication management. Antidepressants like SSRIs and SNRIs are non-addictive and can be prescribed safely during addiction treatment. A psychiatrist monitors medication effectiveness, adjusts dosages, and watches for interactions — all while the person is actively working on recovery from substance use disorder.

Evidence-Based Therapies for Depression in Recovery

Cognitive Behavioral Therapy (CBT)

Cognitive Behavioral Therapy (CBT) is the gold standard for treating co-occurring depression and addiction. CBT helps identify negative thought patterns that drive both depressive episodes and substance use — such as "nothing will ever get better" or "I can't cope without drinking." Patients learn to challenge these distortions and replace them with realistic, constructive thinking. Research consistently shows CBT reduces both depressive symptoms and substance use relapse rates.

Dialectical Behavior Therapy (DBT)

Dialectical Behavior Therapy (DBT) is particularly effective for people with severe depression, emotional dysregulation, or self-harm behaviors alongside addiction. DBT teaches four core skill sets: mindfulness, distress tolerance, emotion regulation, and interpersonal effectiveness. These skills directly address the emotional pain that drives self-medication and provide healthier alternatives to substance use.

Group therapy

Group therapy combats the isolation that is central to both depression and addiction. Hearing others share similar struggles reduces shame and hopelessness. Dual diagnosis groups specifically address how depression and substance use interact, offering peer support from people who understand both conditions. Group settings also build social skills and accountability that support long-term recovery.

Medication management

Antidepressant medications are a critical component of treatment for many people with co-occurring depression and addiction. SSRIs (selective serotonin reuptake inhibitors) like sertraline and fluoxetine are first-line treatments because they are effective, well-tolerated, and — importantly — non-addictive. They carry no abuse potential and do not produce euphoria, making them safe to prescribe during addiction recovery. SNRIs like venlafaxine and duloxetine are also effective alternatives.

Levels of Care for Depression and Addiction

When residential treatment is needed

Residential treatment is recommended when depression is severe — particularly when suicidal ideation is present, when the person has made previous suicide attempts, or when outpatient treatment has failed. Residential programs provide 24/7 psychiatric monitoring, immediate medication adjustments, and a safe environment removed from triggers. People with severe addiction alongside major depression often need this level of structured support to stabilize both conditions.

Intensive Outpatient Programs (IOP)

Intensive Outpatient Programs provide 9–20 hours of structured therapy per week while allowing patients to live at home. IOP is appropriate for moderate depression with addiction, for people stepping down from residential care, or when the person has a stable living environment and support system. Dual diagnosis IOP programs include both addiction counseling and psychiatric services.

Outpatient care with medication management

Standard outpatient treatment works well for mild to moderate depression with substance use disorder, especially when combined with antidepressant medication. This typically involves weekly therapy sessions, regular psychiatric check-ins for medication management, and support group participation. Outpatient care allows people to maintain work, family, and daily responsibilities while receiving treatment.

Choosing the right level of care

The appropriate level of care depends on several factors: severity of depression (mild vs. severe with suicidal thoughts), severity of addiction, previous treatment attempts and outcomes, strength of social support, co-occurring medical conditions, and safety concerns. A professional assessment by a dual diagnosis specialist can determine the best starting point. Many people move through multiple levels of care as they progress in recovery.

Antidepressant Medications in Recovery

SSRIs: the first-line treatment

Selective serotonin reuptake inhibitors (SSRIs) such as sertraline (Zoloft), fluoxetine (Prozac), and escitalopram (Lexapro) are the most commonly prescribed antidepressants for people in addiction recovery. They work by increasing serotonin availability in the brain, gradually improving mood, sleep, and motivation over 4–6 weeks. SSRIs are not addictive, do not produce a high, and have no abuse potential — making them fundamentally different from the substances being treated.

SNRIs and bupropion

Serotonin-norepinephrine reuptake inhibitors (SNRIs) like venlafaxine (Effexor) and duloxetine (Cymbalta) target both serotonin and norepinephrine, which can be helpful for depression with prominent fatigue or chronic pain. Bupropion (Wellbutrin) is another option that acts on dopamine and norepinephrine — it can help with depression, low energy, and is also used to support smoking cessation. None of these medications carry addiction risk.

Addressing the stigma around psychiatric medication

Many people in recovery resist antidepressants because they feel taking any medication contradicts sobriety. This misconception is dangerous. Antidepressants are not mood-altering substances in the way drugs of abuse are — they restore normal brain chemistry rather than creating artificial highs. Untreated depression is one of the strongest predictors of addiction relapse. Taking prescribed, non-addictive medication to manage a medical condition is not a failure of recovery — it supports it.

Why stopping psychiatric meds leads to relapse

A common and harmful pattern occurs when people in recovery stop their antidepressants because they feel better, believe they no longer need them, or face pressure from others to be "medication-free." When depression returns — often within weeks — the emotional pain drives them back to substances. Antidepressant treatment for co-occurring depression should be maintained for at least 12 months after stabilization, and many people benefit from long-term maintenance. Any changes to psychiatric medication should be made gradually under medical supervision.

Frequently Asked Questions About Depression and Addiction

What is dual diagnosis treatment for depression and addiction?

Dual diagnosis treatment addresses both depression and substance use disorders simultaneously through integrated care. This approach recognizes that mental health and addiction affect each other and must be treated together for lasting recovery. Treatment includes psychiatric care, medication management, therapy (CBT, DBT), and specialized counseling that addresses both conditions comprehensively.

Can depression cause substance abuse?

Yes, depression significantly increases the risk of substance abuse. Many people self-medicate depression symptoms with alcohol or drugs, seeking temporary relief from emotional pain, low energy, or insomnia. However, substance use worsens depression long-term by disrupting serotonin and dopamine regulation, creating a vicious cycle. Proper treatment addresses root causes of depression while providing healthier coping strategies than substances.

Will antidepressants interfere with addiction treatment?

No, appropriate antidepressant medication actively supports recovery. Quality dual diagnosis programs work with psychiatrists to find effective antidepressant treatment while addressing addiction. Medications like SSRIs and SNRIs are non-addictive and help stabilize mood, making it easier to engage in therapy and maintain sobriety. Never stop psychiatric medications without medical guidance.

How do I find a treatment center for depression and addiction?

Look for centers explicitly offering dual diagnosis or co-occurring disorder treatment. Verify they have licensed mental health professionals, psychiatric services, medication management capabilities, and experience treating both conditions together. Use our directory to filter for dual diagnosis programs, read reviews, and verify accreditation. Contact admissions teams to discuss your specific needs.

Is residential treatment necessary for depression and addiction?

Not always. Treatment level depends on severity of both conditions, previous treatment attempts, safety concerns, and support system. Some people do well with intensive outpatient care plus medication management. Residential treatment provides 24/7 support for severe depression, suicide risk, or when outpatient treatment hasn't succeeded. A professional assessment determines the most appropriate level of care.

Can addiction cause depression or does depression cause addiction?

The relationship is bidirectional — it works both ways. Depression can lead to substance abuse through self-medication, as people use drugs or alcohol to escape emotional pain. At the same time, chronic substance use alters brain chemistry in ways that cause or worsen depression — alcohol is a central nervous system depressant, stimulant withdrawal causes profound depression, and opioid use disrupts the brain's natural mood regulation. In many cases, both conditions develop and reinforce each other simultaneously, which is why integrated dual diagnosis treatment is essential for lasting recovery.

Will I need antidepressants forever?

Not necessarily. Many people take antidepressants for 12–24 months after their mood stabilizes, then gradually taper off under medical supervision. However, some people with recurrent major depression (three or more episodes) benefit from long-term maintenance medication. The decision depends on depression severity, number of past episodes, family history, and individual response to treatment. What is critical is never stopping antidepressants abruptly — doing so can cause withdrawal symptoms and trigger relapse in both depression and addiction. Always work with your prescribing psychiatrist to make any medication changes.

Medical Review and Sources

Medically Reviewed Updated April 10, 2026

Reviewed by licensed addiction specialists. Information reflects current clinical guidance.

Sources:SAMHSA·NIDA·CDC

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