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Medically Reviewed Content
Updated: May 2026
Sources: SAMHSA, NIDA

Depression & Addiction Treatment Centers Near You

Depression and addiction frequently co-occur, requiring integrated treatment approaches. Find dual diagnosis treatment centers addressing both mental health and substance use disorders through coordinated care and evidence-based therapies.

Found 7,770 rehab centers specializing in depression across the United States.

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Find Depression and Addiction Treatment Centers Near You

Browse dual diagnosis treatment centers below. Filter for programs treating depression and substance abuse together.

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Redpoint Center
Longmont, CO

Situated in Longmont, CO, the Redpoint Center presents an extensive array of rehabilitation services for both adults and youth facing challenges related to substance use disorders alongside mental health concerns. The center features intensive outpatient programs, day treatment sessions, and partial hospitalization, employing various strategies like 12-step methods, anger management classes, and brief intervention techniques. With tailored programs for active-duty military personnel, as well as specific offerings for men and women, the Redpoint Center addresses the needs of different populations. Notably, this facility provides transitional housing, a halfway house, and sober living arrangements to foster a nurturing recovery atmosphere. Individuals looking for effective care in a gender-specific environment will find the Redpoint Center to be an essential asset on their path to recovery.

Reed Behavioral Health
Minneapolis, MN

Reed Behavioral Health, situated in Minneapolis, MN, delivers comprehensive outpatient treatment and support for adults and children facing substance use and co-occurring mental health conditions. Employing strategies such as 12-step facilitation, cognitive behavioral therapy, and brief intervention, the center offers expert care for those with trauma backgrounds and dual diagnoses. Customized plans are available for adults and young adults across the gender spectrum. Committed to high standards of care and scientifically proven methods, Reed Behavioral Health empowers individuals in their path to overcoming addiction and mental health struggles.

Refine Recovery
Beverly Hills, CA

Situated in Beverly Hills, CA, Refine Recovery delivers an all-encompassing range of addiction treatment services tailored for both adults and young adults. The center features residential detox services, around-the-clock care, and short-term residential options. Emphasizing 12-step facilitation, anger management, and brief intervention techniques, Refine Recovery addresses the needs of clients dealing with trauma, dual diagnosis of mental health and substance use disorders, as well as those struggling with pain in conjunction with addiction. Catering to both men and women, this facility is committed to providing top-notch care for individuals in pursuit of effective and customized solutions for substance use problems and related conditions.

Red Willow Counseling and Recovery

Red Willow Counseling and Recovery, located in Salt Lake City, UT, provides a full spectrum of substance abuse treatment options, including intensive outpatient, outpatient, and standard outpatient services. The center employs targeted therapeutic modalities such as anger management, brief intervention, and cognitive behavioral therapy to meet individual requirements. Recognizing the unique challenges faced by different groups, Red Willow offers dedicated programs for active duty military members, adult men, and adult women. This facility is committed to delivering effective and empathetic addiction care to adults and young adults of all genders within a supportive environment.

Reflections Detox Facility

Reflections Detox Facility, located in Novato, CA, provides an extensive range of detox and substance abuse treatment options in a supportive residential environment. Their offerings include around-the-clock residential care as well as short-term programs tailored to various needs. This center focuses on 12-step facilitation while also incorporating distinct methods such as anger management and short intervention sessions. Additionally, it has specialized programs designed for active military members, along with services for adult men and women, accommodating a wide spectrum of clients. Reflections Detox Facility is dedicated to delivering quality care and assistance for adults and young adults striving for recovery from addiction.

Reflections Outpatient

Nestled in Lindon, UT, Reflections Outpatient is dedicated to providing tailored substance use recovery programs for adults and young adults managing co-occurring serious mental health conditions. They offer structured care through intensive outpatient, day treatment, and partial hospitalization programs. Their therapeutic approach incorporates methods such as 12-step facilitation, anger management techniques, and brief intervention strategies. This center serves adult men and women, including those who have faced intimate partner or domestic violence. Reflections Outpatient stands as a crucial support system for individuals pursuing healing and well-being within a nurturing setting designed to address their specific challenges.

Redwood Community Services Inc

Redwood Community Services Inc, situated in Ukiah, CA, delivers a variety of focused therapies for individuals of all ages grappling with substance abuse and concurrent mental health issues. They provide flexible care levels, including intensive outpatient, standard outpatient, and regular outpatient services, all customized using methods such as 12-step facilitation, anger management, and cognitive behavioral therapy. Their programs are designed for adolescents, adult men, and women, emphasizing individual needs. The facility also offers distinct treatment pathways for males and females. Redwood Community Services Inc is recognized for its all-encompassing support and dedication to effective recovery for those facing addiction and mental health obstacles.

Redwood Wabasso Holdings LLC

Redwood Wabasso Holdings LLC, situated in Wabasso, Minnesota, specializes in extensive treatment for substance use issues among adults and young adults. The center offers various levels of care, including intensive outpatient programs, standard outpatient services, and regular outpatient options. By employing evidence-based practices such as 12-step support, cognitive behavioral therapy, and motivational interviewing, the facility customizes its approach to meet the unique needs of each individual. Unique programs are available for men, women, and those facing both mental health and substance use challenges. Committed to delivering high-quality care, Redwood Wabasso fosters a nurturing atmosphere for recovery, with gender-specific programs designed to enhance treatment outcomes for both men and women.

Red Willow Park City

Red Willow Park City, situated in Park City, UT, provides outpatient services for individuals struggling with substance use disorders. Their programs are designed for adults and young adults, with a focus on anger management, brief intervention strategies, and cognitive behavioral therapy. The center caters to a variety of needs with specific offerings for active duty military personnel, adult men, and adult women. Red Willow Park City is dedicated to delivering personalized and effective outpatient recovery support for both male and female clients in the Park City area.

Redwood Recovery
Riverton, UT

Redwood Recovery, situated in Riverton, UT, specializes in treating adult men who are facing substance use challenges along with co-occurring mental health disorders. The center offers various levels of care including intensive outpatient programs, outpatient day treatment, and partial hospitalization. A primary focus is on strategies such as 12-step facilitation, anger management, and brief intervention. Catering to a diverse clientele that includes adults, seniors, and young adults, Redwood Recovery ensures that treatment is personalized for each demographic. The center is particularly noted for its dedication to assisting individuals with complicated needs, including those involved with the criminal justice system. Emphasizing a gender-specific model and offering multiple outpatient treatment options, Redwood Recovery is committed to delivering high-quality care and thorough support for those seeking to overcome their challenges and embark on a journey towards healing.

Reed Behavioral Health

Situated in Wayzata, MN, Reed Behavioral Health provides targeted interventions for individuals, both young and adult, grappling with addiction and co-occurring mental health conditions. Their multifaceted treatment options encompass intensive outpatient, standard outpatient, and flexible outpatient care. Employing proven therapeutic methods like cognitive behavioral therapy, motivational interviewing, and contingency management, the facility delivers personalized support designed for adult men, adult women, and those who have encountered trauma. Reed Behavioral Health is dedicated to delivering exceptional care and assistance to all genders on their journey toward overcoming substance dependence and mental health struggles.

Reflections
Saint Paul, MN

At "Reflections" in Saint Paul, MN, we provide a complete spectrum of recovery programs. Our offerings include structured intensive outpatient care, standard outpatient services, and day treatment or partial hospitalization options for adults and young adults navigating substance use challenges and co-occurring mental health issues. Utilizing brief intervention strategies, cognitive behavioral therapy, and motivational reinforcement, we support adult men and women, including those with a history of trauma. "Reflections" is distinguished by its dedicated approach to individuals with serious emotional disturbances and its provision of transitional living accommodations. We are devoted to delivering exceptional care in a nurturing setting for those on their journey to wellness.

Redeem Healthcare Medical Systems

At Redeem Healthcare Medical Systems in Baltimore, MD, a full spectrum of care is available for individuals struggling with substance use disorders and co-occurring mental health conditions, serving both adults and younger individuals. The center provides various levels of care, including intensive outpatient, day treatment, and partial hospitalization programs. To address specific needs, they offer specialized interventions like anger management, brief intervention strategies, and cognitive behavioral therapy. Redeem Healthcare focuses on distinct populations, such as active duty military, adult men, and adult women, and welcomes adults and young adults of all gender identities. Recognized for its commitment to high-quality, personalized treatment, Redeem Healthcare stands out as a leading option for comprehensive recovery services in Baltimore.

ReDiscover
Lees Summit, MO

Situated in Lees Summit, MO, ReDiscover provides all-encompassing care for individuals battling substance use disorders, including those experiencing concurrent severe mental health challenges. The center's offerings include intensive outpatient, standard outpatient, and day treatment services, employing methodologies like 12-step support, emotional regulation techniques, and brief therapeutic interventions. ReDiscover features tailored programs designed for active military members, adult men, and adult women, demonstrating a commitment to serving varied demographics. This facility welcomes adults and young adults of any gender, prioritizing the delivery of exceptional care to support individuals in their journey toward lasting recovery.

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Redeem Healthcare and Med Sys II Inc, located in Baltimore, MD, provides focused care for adults dealing with substance use disorders and co-occurring mental health challenges. Their structured outpatient and intensive outpatient services incorporate proven therapeutic methods, including cognitive behavioral therapy and techniques for managing anger. This institution is equipped to deliver customized treatment for active military members, adult men, and women. Catering to both adolescents and adults, the facility ensures thorough support regardless of gender. Clients can anticipate receiving high-quality, personalized assistance whether they engage in outpatient day programs or partial hospitalization.

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Fort Collins, CO

Nestled in Fort Collins, CO, Redpoint North delivers a complete spectrum of recovery support for adults and young adults facing addiction. The center features intensive outpatient, day treatment, and partial hospitalization programs, utilizing proven methods like 12-step support, emotional regulation skills, and brief counseling. Redpoint North is particularly adept at addressing dual diagnoses of addiction and significant mental health conditions in adults, along with serious emotional challenges in younger individuals. Dedicated tracks for active military personnel, teenagers, and adult males ensure personalized treatment plans. With options for supported living arrangements and sober residences, Redpoint North is committed to offering effective, gender-informed care for individuals of all genders pursuing sobriety.

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Redwood Community Services Inc in Upper Lake, CA, provides comprehensive residential care around the clock for adult women, seniors, and young adults requiring assistance with substance use. Their treatment approach incorporates 12-step principles, anger management techniques, and cognitive behavioral therapy. They offer specialized support for adult women, individuals with trauma histories, and those managing co-occurring mental health and addiction challenges. Committed to effective, evidence-based practices, Redwood Community Services Inc guides individuals toward lasting recovery.

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Stillwater, MN

At Reflections LLC in Stillwater, MN, we provide extensive support for individuals battling addiction and offer a safe haven in transitional housing. Our specialized programs address the complexities of dual diagnoses, encompassing substance use disorders alongside significant mental health conditions in adults, as well as emotional challenges faced by children. Our treatment options include intensive outpatient services, structured day treatment, and partial hospitalization, all informed by proven therapeutic methods like cognitive behavioral therapy and motivational incentives. We have developed distinct tracks for adult men, adult women, and individuals with a history of trauma, welcoming adults and young adults of all genders. Reflections LLC is committed to delivering exceptional care and individualized recovery plans within a nurturing atmosphere.

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"Reflections of Hope LLP in Wilmington, NC, offers comprehensive substance use treatment through various outpatient formats, including methadone/buprenorphine or naltrexone treatment. This facility provides specialized programs for active duty military personnel, adult men, and adult women. With a focus on anger management, brief intervention, and cognitive behavioral therapy, the center caters to adults and young adults of both genders. The center's dedication to quality care and individualized treatment plans makes it a sought-after choice for those seeking effective and supportive rehabilitation services in the Wilmington area."

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Situated in Baltimore, MD, Reflective Treatment Center provides outpatient detoxification and recovery services for both adults and young adults facing substance use challenges. The center's offerings encompass 12-step facilitation, cognitive behavioral therapy, and anger management. It features specialized programs aimed at aiding active duty military members, as well as separate services for adult men and women. Committed to delivering high-quality care, the facility serves clients of all genders seeking reliable rehabilitation options. Reflective Treatment Center is distinguished by its extensive outpatient capabilities, customized programs to meet varying needs, and reliance on evidence-based treatment methods.

Depression & Substance Use Disorder: Key Facts

Classification

Major Depressive Disorder + Substance Use Disorder (Dual Diagnosis)

Co-occurrence

~1 in 3 people with depression also have SUD (NIDA)

Prevalence

21 million adults with major depressive episode/year (NIMH)

Self-medication

Depression is the #1 reason for substance self-medication

Treatment approach

Integrated dual diagnosis (treat both simultaneously)

Key therapies

CBT, DBT, medication management, group therapy

Medications

SSRIs (non-addictive), SNRIs — safe during addiction treatment

Prognosis

Significantly better outcomes with integrated treatment vs sequential

If you or someone you know is experiencing suicidal thoughts, call 988 (Suicide & Crisis Lifeline) or text 988 immediately. Help is available 24/7.

Depression and Addiction: The Dual Diagnosis Connection

How depression and addiction feed each other

Depression and substance use disorder share a deeply intertwined relationship. Depression causes persistent feelings of emptiness, hopelessness, and emotional pain that drive many people toward alcohol or drugs as a form of self-medication. Substances may provide temporary relief, but they alter brain chemistry in ways that worsen depressive symptoms over time — creating a destructive cycle that accelerates both conditions.

The self-medication cycle

The self-medication cycle is the most common pathway from depression to addiction. A person experiencing persistent sadness, fatigue, or emotional numbness turns to alcohol, opioids, or stimulants to feel better temporarily. As tolerance builds, they need more of the substance to achieve the same relief. Meanwhile, the substance disrupts serotonin and dopamine regulation in the brain, deepening the depression. When the substance wears off, the depression returns worse than before — driving further substance use.

Why treating one without the other fails

Treating addiction without addressing underlying depression leaves the root cause intact. The person achieves sobriety but continues suffering from untreated depression, making relapse nearly inevitable as they seek relief. Conversely, treating depression without addressing active substance use is ineffective because ongoing drug or alcohol use undermines the neurochemical changes that antidepressants and therapy work to achieve. This is why dual diagnosis treatment — addressing both conditions simultaneously — produces significantly better outcomes than treating either condition alone.

Signs of Co-Occurring Depression and Substance Abuse

Recognizing co-occurring depression and substance abuse can be challenging because symptoms overlap. Watch for these warning signs:

Emotional and behavioral signs

  • Persistent sadness combined with increased substance use
  • Withdrawal from friends, family, and activities once enjoyed
  • Using drugs or alcohol specifically to cope with emptiness or hopelessness
  • Feelings of worthlessness or excessive guilt alongside substance use
  • Loss of motivation or interest in recovery efforts

Physical signs

  • Significant changes in sleep patterns — insomnia or oversleeping
  • Appetite and weight changes (loss or gain)
  • Chronic fatigue even with adequate rest
  • Increased substance tolerance requiring higher doses
  • Neglect of personal hygiene and self-care

How Dual Diagnosis Treatment Works

Integrated approach

Dual diagnosis treatment treats depression and addiction as interconnected conditions rather than separate problems. Instead of completing addiction treatment first and then addressing depression (the sequential approach that often fails), integrated programs work on both simultaneously. This means therapy sessions address how depressive thoughts drive substance use, while psychiatric care stabilizes mood to support sobriety.

Psychiatric evaluation during early sobriety

Accurate diagnosis of depression requires evaluation during a period of sobriety, because many substances can mimic or mask depressive symptoms. Alcohol is a depressant that causes sadness and lethargy. Stimulant withdrawal causes profound depression. A psychiatrist experienced in dual diagnosis will conduct thorough assessments during early sobriety to distinguish substance-induced mood changes from underlying major depressive disorder, ensuring the right treatment plan.

Coordinated care teams

Effective dual diagnosis programs use coordinated care teams where psychiatrists, addiction counselors, therapists, and medical staff communicate about each patient's progress. The psychiatrist managing antidepressant medication works closely with the addiction counselor guiding recovery, so treatment decisions account for both conditions. This prevents the common problem of one provider unknowingly undermining another's treatment plan.

Medication management alongside addiction treatment

One of the most important aspects of dual diagnosis care is safe medication management. Antidepressants like SSRIs and SNRIs are non-addictive and can be prescribed safely during addiction treatment. A psychiatrist monitors medication effectiveness, adjusts dosages, and watches for interactions — all while the person is actively working on recovery from substance use disorder.

Evidence-Based Therapies for Depression in Recovery

Cognitive Behavioral Therapy (CBT)

Cognitive Behavioral Therapy (CBT) is the gold standard for treating co-occurring depression and addiction. CBT helps identify negative thought patterns that drive both depressive episodes and substance use — such as "nothing will ever get better" or "I can't cope without drinking." Patients learn to challenge these distortions and replace them with realistic, constructive thinking. Research consistently shows CBT reduces both depressive symptoms and substance use relapse rates.

Dialectical Behavior Therapy (DBT)

Dialectical Behavior Therapy (DBT) is particularly effective for people with severe depression, emotional dysregulation, or self-harm behaviors alongside addiction. DBT teaches four core skill sets: mindfulness, distress tolerance, emotion regulation, and interpersonal effectiveness. These skills directly address the emotional pain that drives self-medication and provide healthier alternatives to substance use.

Group therapy

Group therapy combats the isolation that is central to both depression and addiction. Hearing others share similar struggles reduces shame and hopelessness. Dual diagnosis groups specifically address how depression and substance use interact, offering peer support from people who understand both conditions. Group settings also build social skills and accountability that support long-term recovery.

Medication management

Antidepressant medications are a critical component of treatment for many people with co-occurring depression and addiction. SSRIs (selective serotonin reuptake inhibitors) like sertraline and fluoxetine are first-line treatments because they are effective, well-tolerated, and — importantly — non-addictive. They carry no abuse potential and do not produce euphoria, making them safe to prescribe during addiction recovery. SNRIs like venlafaxine and duloxetine are also effective alternatives.

Levels of Care for Depression and Addiction

When residential treatment is needed

Residential treatment is recommended when depression is severe — particularly when suicidal ideation is present, when the person has made previous suicide attempts, or when outpatient treatment has failed. Residential programs provide 24/7 psychiatric monitoring, immediate medication adjustments, and a safe environment removed from triggers. People with severe addiction alongside major depression often need this level of structured support to stabilize both conditions.

Intensive Outpatient Programs (IOP)

Intensive Outpatient Programs provide 9–20 hours of structured therapy per week while allowing patients to live at home. IOP is appropriate for moderate depression with addiction, for people stepping down from residential care, or when the person has a stable living environment and support system. Dual diagnosis IOP programs include both addiction counseling and psychiatric services.

Outpatient care with medication management

Standard outpatient treatment works well for mild to moderate depression with substance use disorder, especially when combined with antidepressant medication. This typically involves weekly therapy sessions, regular psychiatric check-ins for medication management, and support group participation. Outpatient care allows people to maintain work, family, and daily responsibilities while receiving treatment.

Choosing the right level of care

The appropriate level of care depends on several factors: severity of depression (mild vs. severe with suicidal thoughts), severity of addiction, previous treatment attempts and outcomes, strength of social support, co-occurring medical conditions, and safety concerns. A professional assessment by a dual diagnosis specialist can determine the best starting point. Many people move through multiple levels of care as they progress in recovery.

Antidepressant Medications in Recovery

SSRIs: the first-line treatment

Selective serotonin reuptake inhibitors (SSRIs) such as sertraline (Zoloft), fluoxetine (Prozac), and escitalopram (Lexapro) are the most commonly prescribed antidepressants for people in addiction recovery. They work by increasing serotonin availability in the brain, gradually improving mood, sleep, and motivation over 4–6 weeks. SSRIs are not addictive, do not produce a high, and have no abuse potential — making them fundamentally different from the substances being treated.

SNRIs and bupropion

Serotonin-norepinephrine reuptake inhibitors (SNRIs) like venlafaxine (Effexor) and duloxetine (Cymbalta) target both serotonin and norepinephrine, which can be helpful for depression with prominent fatigue or chronic pain. Bupropion (Wellbutrin) is another option that acts on dopamine and norepinephrine — it can help with depression, low energy, and is also used to support smoking cessation. None of these medications carry addiction risk.

Addressing the stigma around psychiatric medication

Many people in recovery resist antidepressants because they feel taking any medication contradicts sobriety. This misconception is dangerous. Antidepressants are not mood-altering substances in the way drugs of abuse are — they restore normal brain chemistry rather than creating artificial highs. Untreated depression is one of the strongest predictors of addiction relapse. Taking prescribed, non-addictive medication to manage a medical condition is not a failure of recovery — it supports it.

Why stopping psychiatric meds leads to relapse

A common and harmful pattern occurs when people in recovery stop their antidepressants because they feel better, believe they no longer need them, or face pressure from others to be "medication-free." When depression returns — often within weeks — the emotional pain drives them back to substances. Antidepressant treatment for co-occurring depression should be maintained for at least 12 months after stabilization, and many people benefit from long-term maintenance. Any changes to psychiatric medication should be made gradually under medical supervision.

Frequently Asked Questions About Depression and Addiction

What is dual diagnosis treatment for depression and addiction?

Dual diagnosis treatment addresses both depression and substance use disorders simultaneously through integrated care. This approach recognizes that mental health and addiction affect each other and must be treated together for lasting recovery. Treatment includes psychiatric care, medication management, therapy (CBT, DBT), and specialized counseling that addresses both conditions comprehensively.

Can depression cause substance abuse?

Yes, depression significantly increases the risk of substance abuse. Many people self-medicate depression symptoms with alcohol or drugs, seeking temporary relief from emotional pain, low energy, or insomnia. However, substance use worsens depression long-term by disrupting serotonin and dopamine regulation, creating a vicious cycle. Proper treatment addresses root causes of depression while providing healthier coping strategies than substances.

Will antidepressants interfere with addiction treatment?

No, appropriate antidepressant medication actively supports recovery. Quality dual diagnosis programs work with psychiatrists to find effective antidepressant treatment while addressing addiction. Medications like SSRIs and SNRIs are non-addictive and help stabilize mood, making it easier to engage in therapy and maintain sobriety. Never stop psychiatric medications without medical guidance.

How do I find a treatment center for depression and addiction?

Look for centers explicitly offering dual diagnosis or co-occurring disorder treatment. Verify they have licensed mental health professionals, psychiatric services, medication management capabilities, and experience treating both conditions together. Use our directory to filter for dual diagnosis programs, read reviews, and verify accreditation. Contact admissions teams to discuss your specific needs.

Is residential treatment necessary for depression and addiction?

Not always. Treatment level depends on severity of both conditions, previous treatment attempts, safety concerns, and support system. Some people do well with intensive outpatient care plus medication management. Residential treatment provides 24/7 support for severe depression, suicide risk, or when outpatient treatment hasn't succeeded. A professional assessment determines the most appropriate level of care.

Can addiction cause depression or does depression cause addiction?

The relationship is bidirectional — it works both ways. Depression can lead to substance abuse through self-medication, as people use drugs or alcohol to escape emotional pain. At the same time, chronic substance use alters brain chemistry in ways that cause or worsen depression — alcohol is a central nervous system depressant, stimulant withdrawal causes profound depression, and opioid use disrupts the brain's natural mood regulation. In many cases, both conditions develop and reinforce each other simultaneously, which is why integrated dual diagnosis treatment is essential for lasting recovery.

Will I need antidepressants forever?

Not necessarily. Many people take antidepressants for 12–24 months after their mood stabilizes, then gradually taper off under medical supervision. However, some people with recurrent major depression (three or more episodes) benefit from long-term maintenance medication. The decision depends on depression severity, number of past episodes, family history, and individual response to treatment. What is critical is never stopping antidepressants abruptly — doing so can cause withdrawal symptoms and trigger relapse in both depression and addiction. Always work with your prescribing psychiatrist to make any medication changes.

Medical Review and Sources

Medically Reviewed Updated April 10, 2026

Reviewed by licensed addiction specialists. Information reflects current clinical guidance.

Sources:SAMHSA·NIDA·CDC

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