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Medically Reviewed Content
Updated: May 2026
Sources: SAMHSA, NIDA

Depression & Addiction Treatment Centers Near You

Depression and addiction frequently co-occur, requiring integrated treatment approaches. Find dual diagnosis treatment centers addressing both mental health and substance use disorders through coordinated care and evidence-based therapies.

Found 7,770 rehab centers specializing in depression across the United States.

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Find Depression and Addiction Treatment Centers Near You

Browse dual diagnosis treatment centers below. Filter for programs treating depression and substance abuse together.

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Stages of Recovery Inc

Situated in Waco, TX, Stages of Recovery Inc provides targeted treatment for adults facing substance use challenges alongside significant mental health disorders, as well as emotional issues in children. The center features a range of treatment options including intensive outpatient, outpatient, and day programs, utilizing methods such as 12-step support, anger management, and brief intervention strategies. It offers specialized programs for military personnel, adult males, survivors of intimate partner violence, and other domestic violence victims, catering to individuals of all ages and genders. Stages of Recovery Inc emphasizes personalized care plans and evidence-supported techniques to assist clients in their recovery process.

Stages of Recovery Inc
Oklahoma City, OK

Situated in Oklahoma City, OK, Stages of Recovery Inc delivers an extensive variety of treatment services aimed at addressing substance use issues for both adults and young adults. The center focuses on managing co-occurring substance use disorders in conjunction with significant mental health conditions or emotional challenges. With options including intensive outpatient, outpatient, and standard outpatient treatment, Stages of Recovery Inc offers personalized care through methods like 12-step facilitation, anger management, and brief intervention strategies. This facility is particularly recognized for its unique programs catering to active military personnel, adult males, and survivors of intimate partner or domestic violence. Committed to serving both male and female clients, Stages of Recovery Inc strives to provide exceptional, customized support to assist individuals in their recovery journeys.

Stages of Recovery Inc

Stages of Recovery Inc in Lubbock, TX provides extensive treatment for substance use issues, catering to both adults and children who also face mental health challenges. The center offers various programs, including intensive outpatient, outpatient, and day treatment, and emphasizes methods such as 12-step support, anger management, and concise intervention strategies. There are specialized offerings for active military members, adult men, and survivors of intimate partner violence. With a commitment to individualized care for all clients, regardless of gender, the center strives to deliver effective rehabilitation services in a nurturing setting, helping individuals navigate their recovery journey.

Stairway Resource Center
Woodland Hills, CA

Situated in Woodland Hills, CA, the Stairway Resource Center delivers a wide range of rehabilitation services aimed at adults and young adults facing challenges related to substance use and concurrent mental health conditions. The center specializes in intensive outpatient programs, outpatient day treatment, and partial hospitalization. Emphasizing approaches such as 12-step facilitation, anger management, and brief intervention, the center serves both men and women, including those who have encountered intimate partner violence. Stairway Resource Center is committed to offering exceptional care that is customized to the specific needs of each client, facilitating a supportive and successful recovery experience.

Starlite Recovery Center
Center Point, TX

At Starlite Recovery Center in Center Point, TX, adults and young adults can access a complete spectrum of addiction care. The center delivers detox, substance abuse treatment, and dedicated support for dual diagnoses involving serious mental health or emotional conditions. Offering diverse pathways like intensive outpatient, extended residential stays, and outpatient services, Starlite Recovery Center adapts to individual requirements. Their recovery model incorporates 12-step guidance, anger management techniques, and targeted interventions, fostering a tailored and successful path to sobriety. Specific programs are also provided for active military personnel, adult men, and adult women. Starlite Recovery Center is committed to delivering superior support for those pursuing freedom from addiction.

Stable Community Services

Stable Community Services located in Burlington, NJ, provides an extensive selection of treatment options for those facing challenges with substance abuse and related mental health issues. This center features intensive outpatient programs, standard outpatient services, and specialized pathways for individuals experiencing co-occurring disorders. Emphasizing methods such as 12-step support, anger management strategies, and cognitive behavioral therapy, the facility customizes its approach to fit the diverse requirements of both adults and youth. Additionally, it offers transitional housing and sober living arrangements, fostering a nurturing atmosphere for clients of all genders who are committed to recovery. With a dedication to high-quality treatment, Stable Community Services emerges as a reliable option for individuals embarking on their healing journey.

Star Center Inc
Detroit, MI

Located in Detroit, MI, Star Center Inc specializes in outpatient services for adults and young adults dealing with substance use issues. The center emphasizes motivational interviewing techniques and strategies for preventing relapse, offering customized counseling for those facing substance use disorders. They feature distinct programs tailored to adult men, women, and individuals impacted by domestic or intimate partner violence. The treatment options include outpatient services for methadone/buprenorphine or naltrexone, alongside ongoing outpatient support for both genders. Star Center Inc is committed to delivering high-quality, personalized care to assist individuals as they work towards recovery.

Starcare Specialty Health System

Starcare Specialty Health System, located in Lubbock, TX, provides extensive outpatient care for individuals struggling with addiction and related mental health challenges. They offer tailored programs for adults and youth, with specific support for expectant and new mothers and those with complex dual diagnoses. Employing proven methods such as cognitive behavioral therapy and motivational interviewing, the center emphasizes preventing relapse and delivering personalized support. Starcare fosters a nurturing and encouraging setting for healing, accommodating all ages and genders. For those desiring robust treatment that addresses overall wellness, this institution is committed to guiding you toward sustained recovery and improved mental health.

Starlight Community Services Inc

Starlight Community Services Inc, located in San Jose, CA, provides exceptional outpatient care for adults battling substance abuse and complex mental health conditions, as well as children experiencing emotional challenges. Their comprehensive approach includes 12-step integration, anger management techniques, and concise intervention methods. The center actively supports adolescents, adult men, and adult women, demonstrating a commitment to diverse populations. They are dedicated to delivering superior treatment and personalized strategies to meet every individual's specific requirements. For those in search of supportive and successful recovery options, this organization stands as a guiding light.

Stage by Staige
Kasson, MN

Situated in Kasson, MN, Stage by Staige specializes in treatment for adults and young adults struggling with substance use and concurrent significant mental health challenges or emotional issues. This center offers a range of programs, including intensive outpatient, outpatient, and standard outpatient care, utilizing methods like 12-step facilitation, anger management, and brief intervention strategies. They provide distinct programs designed for adult men, adult women, and individuals who have faced sexual abuse. With an emphasis on catering to various genders and age groups, Stage by Staige delivers thorough support for anyone on their path to recovery. Their exceptional services and customized treatment plans position them as a leading option for addiction rehabilitation.

StarCare Specialty Health System

StarCare Specialty Health System, located in Lubbock, TX, specializes in outpatient care for individuals dealing with substance use disorders and accompanying mental health challenges in both adults and children. The center employs a variety of evidence-based methods, including motivational interviewing, brief interventions, and 12-step support, to provide personalized treatment plans for adult clients, encompassing men, women, and those facing dual diagnoses. With a particular emphasis on young adults and offering a selection of gender-specific programs, StarCare is dedicated to delivering customized care for every individual. Its unwavering commitment to high-quality treatment and wide-ranging services positions StarCare as a reliable option for effective and empathetic rehabilitation in the Lubbock community.

Starlight Community Services

Starlight Community Services, located in San Jose, CA, provides outpatient treatment for adults facing substance use challenges alongside significant mental health disorders and emotional issues in children. Their customized programs incorporate 12-step support, anger management techniques, and short-term interventions. With specific pathways designed for adolescents, adult men, and adult women, the center serves a variety of age groups and genders. Committed to compassionate care and utilizing evidence-based methods, this facility emphasizes holistic recovery and tailored assistance. If you or someone you care about requires thorough addiction treatment in a supportive setting, Starlight Community Services is committed to helping you achieve sustainable recovery.

STARS Nashville TX/Recovery

STARS Nashville TX/Recovery, located in Nashville, TN, specializes in providing multifaceted addiction treatment for adults and young individuals struggling with co-occurring serious mental health conditions or emotional distress. The facility offers a spectrum of care, including intensive outpatient, outpatient, and standard outpatient services, all designed to address specific client requirements. Targeted programs are available for adolescents, adult women, and individuals who have endured sexual abuse. This center prioritizes high-quality support, welcoming both male and female patients. STARS Nashville TX/Recovery is recognized for its commitment to offering impactful treatment and ongoing assistance to those pursuing healing from substance dependence and mental health concerns.

START Treatment and Recovery Centers

START Treatment and Recovery Centers, located in New York, NY, delivers focused outpatient programs for substance use treatment aimed at both adults and young adults. The center employs proven strategies, including brief interventions, cognitive behavioral therapy, and motivational interviewing, to ensure customized support for individuals on the path to recovery. With an emphasis on inclusivity, START features dedicated programs for adult men and women, as well as clients who have faced incidents of intimate partner or domestic violence. Moreover, the center offers outpatient treatment options using methadone, buprenorphine, or naltrexone, fostering a well-rounded and supportive atmosphere for clients striving for sobriety.

Stanislaus Recovery Center

Stanislaus Recovery Center, located in Ceres, CA, provides a wide array of addiction recovery services for both adults and young adults. The facility offers detox services, treatment for substance use disorders, and targeted support for individuals dealing with both addiction and serious mental health challenges, as well as for children experiencing significant emotional issues. Treatment options encompass intensive outpatient services, long-term residential care, and various outpatient programs, allowing for a personalized treatment strategy that caters to each person's unique situation. Additionally, the center features specialized programs for men and women, as well as individuals who have faced domestic or intimate partner violence. By focusing on techniques such as 12-step facilitation, anger management, and brief intervention strategies, the center promotes a comprehensive recovery process, ensuring high-quality support for all clients.

START Treatment and Recovery Centers

START Treatment and Recovery Centers, located in New York, NY, provides extensive outpatient treatment for adults dealing with substance use issues, including those facing serious mental health challenges concurrently. The center emphasizes specialized interventions such as cognitive behavioral therapy, anger management, and short-term therapies, catering to both male and female clients. START's programs are inclusive, addressing the needs of active military members, seniors, and younger individuals, ensuring that treatment plans are customized for each person's circumstances. The center also offers outpatient options for methadone/buprenorphine or naltrexone treatments, focusing on delivering high-quality care to facilitate recovery. With a commitment to meeting the distinct requirements of every client, START Treatment and Recovery Centers fosters a nurturing atmosphere for individuals on their path to overcoming addiction.

START Treatment and Recovery Centers

Situated in New York, NY, START Treatment and Recovery Centers provides comprehensive services such as outpatient detox, treatment for substance use disorders, and outpatient options for methadone, buprenorphine, or naltrexone. The center employs various therapeutic methods, including anger management, brief interventions, and cognitive behavioral therapy. It features specialized programs designed for active duty military personnel as well as adult men and women, addressing a wide range of needs. Serving both adults and young adults regardless of gender, START Treatment and Recovery Centers is committed to delivering personalized, high-quality care to support recovery and well-being in a nurturing atmosphere.

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Stages of Recovery Inc in Abilene, TX, delivers an extensive array of evidence-informed therapies for addressing substance use disorders and concurrent mental health issues in both adults and children. The center features specialized services for active military members, men, and individuals who have experienced domestic abuse, ensuring that the care provided is customized to meet varied requirements. Their outpatient services, which encompass treatments such as methadone and buprenorphine, serve both adults and youths. By employing methods including 12-step programs and anger management techniques, the facility aims to promote a well-rounded recovery process. Stages of Recovery Inc is committed to high standards of care, supported by a collaborative team focused on helping clients achieve enduring sobriety and enhanced mental health.

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Decatur, GA

STAND Inc, located in Decatur, GA, specializes in extensive treatment for substance use, emphasizing transitional housing and sober living arrangements. The facility offers various programs including intensive outpatient treatment, outpatient day treatment, and partial hospitalization, employing proven methods such as anger management, cognitive behavioral therapy, and brief interventions. STAND Inc is particularly recognized for its tailored programs aimed at adult males, those facing intimate partner violence, survivors of domestic abuse, and individuals living with HIV/AIDS. The center serves both adults and young adults of all genders, ensuring a nurturing and high-quality setting for individuals on their recovery journey from addiction.

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Baltimore, MD

Standing Strong in Baltimore, MD, delivers extensive support for men battling addiction, incorporating structured living environments. Their expertise lies in addressing dual diagnoses of substance abuse and significant mental health conditions in adults, alongside emotional challenges in younger individuals. Offering a range of treatment durations, including extended stays and shorter programs, the center employs proven therapeutic approaches such as cognitive behavioral therapy and motivational interviewing. Specialized services are available for individuals managing both mental health concerns and substance dependence. Primarily serving adult males, Standing Strong is dedicated to providing personalized, effective recovery pathways for those facing addiction and mental well-being hurdles.

Depression & Substance Use Disorder: Key Facts

Classification

Major Depressive Disorder + Substance Use Disorder (Dual Diagnosis)

Co-occurrence

~1 in 3 people with depression also have SUD (NIDA)

Prevalence

21 million adults with major depressive episode/year (NIMH)

Self-medication

Depression is the #1 reason for substance self-medication

Treatment approach

Integrated dual diagnosis (treat both simultaneously)

Key therapies

CBT, DBT, medication management, group therapy

Medications

SSRIs (non-addictive), SNRIs — safe during addiction treatment

Prognosis

Significantly better outcomes with integrated treatment vs sequential

If you or someone you know is experiencing suicidal thoughts, call 988 (Suicide & Crisis Lifeline) or text 988 immediately. Help is available 24/7.

Depression and Addiction: The Dual Diagnosis Connection

How depression and addiction feed each other

Depression and substance use disorder share a deeply intertwined relationship. Depression causes persistent feelings of emptiness, hopelessness, and emotional pain that drive many people toward alcohol or drugs as a form of self-medication. Substances may provide temporary relief, but they alter brain chemistry in ways that worsen depressive symptoms over time — creating a destructive cycle that accelerates both conditions.

The self-medication cycle

The self-medication cycle is the most common pathway from depression to addiction. A person experiencing persistent sadness, fatigue, or emotional numbness turns to alcohol, opioids, or stimulants to feel better temporarily. As tolerance builds, they need more of the substance to achieve the same relief. Meanwhile, the substance disrupts serotonin and dopamine regulation in the brain, deepening the depression. When the substance wears off, the depression returns worse than before — driving further substance use.

Why treating one without the other fails

Treating addiction without addressing underlying depression leaves the root cause intact. The person achieves sobriety but continues suffering from untreated depression, making relapse nearly inevitable as they seek relief. Conversely, treating depression without addressing active substance use is ineffective because ongoing drug or alcohol use undermines the neurochemical changes that antidepressants and therapy work to achieve. This is why dual diagnosis treatment — addressing both conditions simultaneously — produces significantly better outcomes than treating either condition alone.

Signs of Co-Occurring Depression and Substance Abuse

Recognizing co-occurring depression and substance abuse can be challenging because symptoms overlap. Watch for these warning signs:

Emotional and behavioral signs

  • Persistent sadness combined with increased substance use
  • Withdrawal from friends, family, and activities once enjoyed
  • Using drugs or alcohol specifically to cope with emptiness or hopelessness
  • Feelings of worthlessness or excessive guilt alongside substance use
  • Loss of motivation or interest in recovery efforts

Physical signs

  • Significant changes in sleep patterns — insomnia or oversleeping
  • Appetite and weight changes (loss or gain)
  • Chronic fatigue even with adequate rest
  • Increased substance tolerance requiring higher doses
  • Neglect of personal hygiene and self-care

How Dual Diagnosis Treatment Works

Integrated approach

Dual diagnosis treatment treats depression and addiction as interconnected conditions rather than separate problems. Instead of completing addiction treatment first and then addressing depression (the sequential approach that often fails), integrated programs work on both simultaneously. This means therapy sessions address how depressive thoughts drive substance use, while psychiatric care stabilizes mood to support sobriety.

Psychiatric evaluation during early sobriety

Accurate diagnosis of depression requires evaluation during a period of sobriety, because many substances can mimic or mask depressive symptoms. Alcohol is a depressant that causes sadness and lethargy. Stimulant withdrawal causes profound depression. A psychiatrist experienced in dual diagnosis will conduct thorough assessments during early sobriety to distinguish substance-induced mood changes from underlying major depressive disorder, ensuring the right treatment plan.

Coordinated care teams

Effective dual diagnosis programs use coordinated care teams where psychiatrists, addiction counselors, therapists, and medical staff communicate about each patient's progress. The psychiatrist managing antidepressant medication works closely with the addiction counselor guiding recovery, so treatment decisions account for both conditions. This prevents the common problem of one provider unknowingly undermining another's treatment plan.

Medication management alongside addiction treatment

One of the most important aspects of dual diagnosis care is safe medication management. Antidepressants like SSRIs and SNRIs are non-addictive and can be prescribed safely during addiction treatment. A psychiatrist monitors medication effectiveness, adjusts dosages, and watches for interactions — all while the person is actively working on recovery from substance use disorder.

Evidence-Based Therapies for Depression in Recovery

Cognitive Behavioral Therapy (CBT)

Cognitive Behavioral Therapy (CBT) is the gold standard for treating co-occurring depression and addiction. CBT helps identify negative thought patterns that drive both depressive episodes and substance use — such as "nothing will ever get better" or "I can't cope without drinking." Patients learn to challenge these distortions and replace them with realistic, constructive thinking. Research consistently shows CBT reduces both depressive symptoms and substance use relapse rates.

Dialectical Behavior Therapy (DBT)

Dialectical Behavior Therapy (DBT) is particularly effective for people with severe depression, emotional dysregulation, or self-harm behaviors alongside addiction. DBT teaches four core skill sets: mindfulness, distress tolerance, emotion regulation, and interpersonal effectiveness. These skills directly address the emotional pain that drives self-medication and provide healthier alternatives to substance use.

Group therapy

Group therapy combats the isolation that is central to both depression and addiction. Hearing others share similar struggles reduces shame and hopelessness. Dual diagnosis groups specifically address how depression and substance use interact, offering peer support from people who understand both conditions. Group settings also build social skills and accountability that support long-term recovery.

Medication management

Antidepressant medications are a critical component of treatment for many people with co-occurring depression and addiction. SSRIs (selective serotonin reuptake inhibitors) like sertraline and fluoxetine are first-line treatments because they are effective, well-tolerated, and — importantly — non-addictive. They carry no abuse potential and do not produce euphoria, making them safe to prescribe during addiction recovery. SNRIs like venlafaxine and duloxetine are also effective alternatives.

Levels of Care for Depression and Addiction

When residential treatment is needed

Residential treatment is recommended when depression is severe — particularly when suicidal ideation is present, when the person has made previous suicide attempts, or when outpatient treatment has failed. Residential programs provide 24/7 psychiatric monitoring, immediate medication adjustments, and a safe environment removed from triggers. People with severe addiction alongside major depression often need this level of structured support to stabilize both conditions.

Intensive Outpatient Programs (IOP)

Intensive Outpatient Programs provide 9–20 hours of structured therapy per week while allowing patients to live at home. IOP is appropriate for moderate depression with addiction, for people stepping down from residential care, or when the person has a stable living environment and support system. Dual diagnosis IOP programs include both addiction counseling and psychiatric services.

Outpatient care with medication management

Standard outpatient treatment works well for mild to moderate depression with substance use disorder, especially when combined with antidepressant medication. This typically involves weekly therapy sessions, regular psychiatric check-ins for medication management, and support group participation. Outpatient care allows people to maintain work, family, and daily responsibilities while receiving treatment.

Choosing the right level of care

The appropriate level of care depends on several factors: severity of depression (mild vs. severe with suicidal thoughts), severity of addiction, previous treatment attempts and outcomes, strength of social support, co-occurring medical conditions, and safety concerns. A professional assessment by a dual diagnosis specialist can determine the best starting point. Many people move through multiple levels of care as they progress in recovery.

Antidepressant Medications in Recovery

SSRIs: the first-line treatment

Selective serotonin reuptake inhibitors (SSRIs) such as sertraline (Zoloft), fluoxetine (Prozac), and escitalopram (Lexapro) are the most commonly prescribed antidepressants for people in addiction recovery. They work by increasing serotonin availability in the brain, gradually improving mood, sleep, and motivation over 4–6 weeks. SSRIs are not addictive, do not produce a high, and have no abuse potential — making them fundamentally different from the substances being treated.

SNRIs and bupropion

Serotonin-norepinephrine reuptake inhibitors (SNRIs) like venlafaxine (Effexor) and duloxetine (Cymbalta) target both serotonin and norepinephrine, which can be helpful for depression with prominent fatigue or chronic pain. Bupropion (Wellbutrin) is another option that acts on dopamine and norepinephrine — it can help with depression, low energy, and is also used to support smoking cessation. None of these medications carry addiction risk.

Addressing the stigma around psychiatric medication

Many people in recovery resist antidepressants because they feel taking any medication contradicts sobriety. This misconception is dangerous. Antidepressants are not mood-altering substances in the way drugs of abuse are — they restore normal brain chemistry rather than creating artificial highs. Untreated depression is one of the strongest predictors of addiction relapse. Taking prescribed, non-addictive medication to manage a medical condition is not a failure of recovery — it supports it.

Why stopping psychiatric meds leads to relapse

A common and harmful pattern occurs when people in recovery stop their antidepressants because they feel better, believe they no longer need them, or face pressure from others to be "medication-free." When depression returns — often within weeks — the emotional pain drives them back to substances. Antidepressant treatment for co-occurring depression should be maintained for at least 12 months after stabilization, and many people benefit from long-term maintenance. Any changes to psychiatric medication should be made gradually under medical supervision.

Frequently Asked Questions About Depression and Addiction

What is dual diagnosis treatment for depression and addiction?

Dual diagnosis treatment addresses both depression and substance use disorders simultaneously through integrated care. This approach recognizes that mental health and addiction affect each other and must be treated together for lasting recovery. Treatment includes psychiatric care, medication management, therapy (CBT, DBT), and specialized counseling that addresses both conditions comprehensively.

Can depression cause substance abuse?

Yes, depression significantly increases the risk of substance abuse. Many people self-medicate depression symptoms with alcohol or drugs, seeking temporary relief from emotional pain, low energy, or insomnia. However, substance use worsens depression long-term by disrupting serotonin and dopamine regulation, creating a vicious cycle. Proper treatment addresses root causes of depression while providing healthier coping strategies than substances.

Will antidepressants interfere with addiction treatment?

No, appropriate antidepressant medication actively supports recovery. Quality dual diagnosis programs work with psychiatrists to find effective antidepressant treatment while addressing addiction. Medications like SSRIs and SNRIs are non-addictive and help stabilize mood, making it easier to engage in therapy and maintain sobriety. Never stop psychiatric medications without medical guidance.

How do I find a treatment center for depression and addiction?

Look for centers explicitly offering dual diagnosis or co-occurring disorder treatment. Verify they have licensed mental health professionals, psychiatric services, medication management capabilities, and experience treating both conditions together. Use our directory to filter for dual diagnosis programs, read reviews, and verify accreditation. Contact admissions teams to discuss your specific needs.

Is residential treatment necessary for depression and addiction?

Not always. Treatment level depends on severity of both conditions, previous treatment attempts, safety concerns, and support system. Some people do well with intensive outpatient care plus medication management. Residential treatment provides 24/7 support for severe depression, suicide risk, or when outpatient treatment hasn't succeeded. A professional assessment determines the most appropriate level of care.

Can addiction cause depression or does depression cause addiction?

The relationship is bidirectional — it works both ways. Depression can lead to substance abuse through self-medication, as people use drugs or alcohol to escape emotional pain. At the same time, chronic substance use alters brain chemistry in ways that cause or worsen depression — alcohol is a central nervous system depressant, stimulant withdrawal causes profound depression, and opioid use disrupts the brain's natural mood regulation. In many cases, both conditions develop and reinforce each other simultaneously, which is why integrated dual diagnosis treatment is essential for lasting recovery.

Will I need antidepressants forever?

Not necessarily. Many people take antidepressants for 12–24 months after their mood stabilizes, then gradually taper off under medical supervision. However, some people with recurrent major depression (three or more episodes) benefit from long-term maintenance medication. The decision depends on depression severity, number of past episodes, family history, and individual response to treatment. What is critical is never stopping antidepressants abruptly — doing so can cause withdrawal symptoms and trigger relapse in both depression and addiction. Always work with your prescribing psychiatrist to make any medication changes.

Medical Review and Sources

Medically Reviewed Updated April 10, 2026

Reviewed by licensed addiction specialists. Information reflects current clinical guidance.

Sources:SAMHSA·NIDA·CDC

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Speak with a compassionate specialist who can help you find the right dual diagnosis program for depression and addiction — 100% free and confidential, available 24/7.