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Medically Reviewed Content
Updated: May 2026
Sources: SAMHSA, NIDA

Depression & Addiction Treatment Centers Near You

Depression and addiction frequently co-occur, requiring integrated treatment approaches. Find dual diagnosis treatment centers addressing both mental health and substance use disorders through coordinated care and evidence-based therapies.

Found 7,770 rehab centers specializing in depression across the United States.

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Find Depression and Addiction Treatment Centers Near You

Browse dual diagnosis treatment centers below. Filter for programs treating depression and substance abuse together.

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Covenant Hills Treatment Center
San Juan Capistrano, CA

Located in San Juan Capistrano, California, Covenant Hills Treatment Center provides a wide array of services focused on the treatment of substance use for both adults and young adults. Emphasizing intensive outpatient programs and transitional housing, this center specializes in offering care for men and women, including individuals with trauma histories. Utilizing proven methods such as 12-step facilitation, anger management, and brief intervention, Covenant Hills Treatment Center is dedicated to delivering customized and effective care solutions. The center also offers outpatient treatment options with methadone/buprenorphine or naltrexone, addressing various recovery needs in a nurturing atmosphere. Its dedication to high-quality support and tailored treatment strategies sets it apart in the field.

Covenant House Florida
Fort Lauderdale, FL

Covenant House Florida, situated in Fort Lauderdale, FL, delivers extensive addiction recovery services through a range of options: extended stay residential, round-the-clock residential, and brief residential stays. The facility focuses on methods such as 12-step program integration, emotional regulation skills, and immediate intervention strategies. Distinctive offerings are available for individuals who have faced trauma, those with co-occurring mental health and addiction issues, and young adults. Catering to adults and adolescents alike, the center offers tailored support for both male and female individuals. Covenant House Florida is committed to delivering excellent, personalized support to guide individuals toward lasting recovery.

CPF Breakthrough LLC

CPF Breakthrough LLC, located in Spokane, WA, provides extensive care for substance use disorders, utilizing several program structures, including intensive outpatient, standard outpatient, and day treatment (partial hospitalization). Their approach emphasizes 12-step facilitation, anger management techniques, and brief intervention strategies. CPF Breakthrough LLC is equipped to support active military members, as well as adult men and women. They extend their services to both young adults and adults of any gender, offering customized treatment plans. This facility is devoted to delivering high-quality, varied therapeutic options to support individuals on their journey to sustained sobriety.

Cranberry Township Comp Trt Center

Situated in Cranberry Township, PA, the Cranberry Township Comp Trt Center delivers extensive substance use rehabilitation services for both adults and young adults. The facility offers outpatient treatments including methadone/buprenorphine and naltrexone, along with regular outpatient options and 12-step facilitation, anger management, and brief intervention strategies. Tailored programs are available specifically for active duty military personnel, as well as separate services for adult men and women to meet various needs. By providing gender-specific care, the center fosters a personalized approach to treatment. The focus on high-quality care and individualized assistance is aimed at supporting clients throughout their recovery journey.

Cow Creek Health and Wellness

In Roseburg, OR, Cow Creek Health and Wellness provides extensive outpatient care for individuals struggling with substance use disorders. Their expertise lies in techniques such as 12-step facilitation, anger management, and brief intervention strategies. They feature specialized programming for young people, adult males, and adult females. The center delivers tailored services to both adults and younger individuals, with treatment plans adjusted based on gender. Cow Creek Health and Wellness is dedicated to offering exceptional, customized support to guide people toward healing. For those looking for impactful addiction therapy in a supportive setting, this center is a notable option.

Cow Creek Health and Wellness Center

Cow Creek Health and Wellness Center in Canyonville, OR, provides extensive outpatient care for individuals pursuing sobriety. They offer distinct programs for teenagers, adult men, and adult women, fostering a welcoming atmosphere for everyone. Employing proven methods like 12-step support, emotional regulation, and concise counseling, the center emphasizes total well-being and sustained abstinence. Options for medication-assisted treatment, including methadone, buprenorphine, or naltrexone, are available. Cow Creek Health and Wellness Center is committed to delivering excellent services and individualized assistance to guide clients toward enduring recovery.

Create Inc
Minneapolis, MN

Situated in Minneapolis, MN, Create Inc specializes in extensive treatment options for individuals dealing with substance use issues, catering to both adults and young adults. The facility features various treatment modalities, including intensive outpatient services and standard outpatient care. By incorporating evidence-based techniques such as brief interventions, cognitive behavioral therapy, and motivational interviewing, Create Inc customizes its programs to fit the specific requirements of each person. Additionally, the center offers tailored programs for men, women, and those who have faced trauma. Committed to delivering high-quality care, this center fosters a nurturing atmosphere for those on their path to recovery, with programs designed to meet the distinct needs of both genders.

CPC Integrated Health

CPC Integrated Health, situated in Red Bank, New Jersey, provides targeted recovery programs for adults and young adults managing addiction and related mental health conditions. Their services include comprehensive outpatient treatment, standard outpatient care, and medication-assisted treatment utilizing methadone, buprenorphine, or naltrexone. The center emphasizes therapeutic approaches such as anger management, brief intervention, and cognitive behavioral therapy, creating individualized plans for adult men and women, particularly those affected by intimate partner or domestic violence. CPC Integrated Health fosters a secure environment for all clients, committed to high-quality support and healing for those on their journey to wellness.

Covert Action LLC
Des Moines, IA

Covert Action LLC, situated in Des Moines, IA, provides outpatient treatment programs for substance use, targeting both adult men and women, along with young adults. This facility emphasizes specialized therapies such as cognitive behavioral therapy, motivational interviewing, and contingency management with motivational incentives. It also offers tailored programs for individuals who have undergone sexual abuse. Clients can access methadone/buprenorphine or naltrexone treatments on an outpatient basis, in addition to standard outpatient services. With a commitment to high-quality care and personalized treatment plans, Covert Action LLC stands out as a reliable option for effective and compassionate addiction recovery support in the Des Moines region.

CPC Integrated Health

CPC Integrated Health, situated in Matawan, NJ, provides extensive support for adults and young adults facing substance use challenges. This center is particularly adept at addressing co-occurring substance use disorders alongside significant mental health issues or emotional difficulties in children. Emphasizing intensive outpatient programs, regular outpatient services, and outpatient treatments using methadone, buprenorphine, or naltrexone, CPC Integrated Health employs a variety of evidence-based strategies, including anger management, brief interventions, and cognitive behavioral therapy. They also offer specialized programs designed for adult men and women, as well as those who have survived intimate partner or domestic violence. Committed to delivering high-quality care, this center aims to assist individuals throughout their recovery process.

CPC Integrated Health

CPC Integrated Health, situated in Howell, NJ, provides an extensive range of treatment options for substance use and co-occurring disorders for both adults and children. The center offers intensive outpatient and outpatient programs along with specialized services including anger management and cognitive behavioral therapy. Focusing on personalized care, CPC Integrated Health has distinct programs designed for adolescents, adult men, and adult women. Emphasizing a client-focused philosophy, the facility serves individuals of all genders in need of effective addiction treatment and mental health support, fostering a nurturing setting for recovery.

CPC Integrated Health

CPC Integrated Health in Freehold, NJ, delivers extensive care for addiction and dual diagnoses involving significant mental health conditions. They offer robust outpatient programs, including intensive options and medication-assisted treatment with methadone, buprenorphine, or naltrexone. Their therapeutic framework incorporates anger management, brief intervention strategies, and cognitive behavioral therapy. CPC Integrated Health provides personalized recovery plans for teens, adult males, and adult females, supporting clients of all ages and genders in their journey toward wellness.

Crawford County Drug and Alcohol

Crawford County Drug and Alcohol, positioned in Meadville, PA, provides an extensive range of treatment options for adults and seniors dealing with substance use issues. The center features a variety of programs, including intensive outpatient treatment, outpatient care, and standard outpatient services, all designed to meet the specific needs of each individual. Employing scientifically supported methods like 12-step facilitation, brief intervention techniques, and cognitive behavioral therapy, the facility promotes a comprehensive approach to recovery. Specialized programs are available for teens, men, and women, creating an inclusive atmosphere for all clients. With a commitment to high-quality care and custom treatment strategies, Crawford County Drug and Alcohol aims to support individuals on their path to enduring sobriety.

Creative Change Counseling

Situated in Trenton, NJ, Creative Change Counseling delivers a holistic approach to substance use recovery for those in need. The facility presents a variety of treatment options, including intensive outpatient care, general outpatient services, and a partial hospitalization program during the day. Emphasizing methods such as 12-step support, anger management, and short-term interventions, this center addresses the needs of active military personnel, young individuals, and adult males. With a commitment to providing specialized care for children and adolescents across all gender identities, Creative Change Counseling prioritizes personalized support for every person's path towards sobriety.

CRASH Inc
San Diego, CA

CRASH Inc, situated in San Diego, CA, stands as a leading facility dedicated to providing advanced care for individuals battling substance use disorders and co-occurring mental health conditions in adults, as well as addressing serious emotional disturbances in children. The center offers diverse care modalities, including inpatient hospital stays, extended residential programs, and round-the-clock residential services, ensuring robust support for adults, older adults, and young adults across all genders. CRASH Inc distinguishes itself with specialized services catering to adult men, adult women, and those who have endured intimate partner or domestic violence. Employing evidence-based strategies such as 12-step facilitation, anger management techniques, and brief intervention methods, this institution guarantees excellent, personalized treatment plans.

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Cambridge, MD

Cove Recovery LLC in Cambridge, MD, delivers targeted substance abuse care for adults and adolescents grappling with concurrent severe mental health conditions or emotional challenges. Their services encompass intensive outpatient, standard outpatient, and medication-assisted treatment with methadone, buprenorphine, or naltrexone. Utilizing methodologies such as 12-step facilitation, anger management, and brief interventions, this establishment supports adult men and women, including survivors of intimate partner or domestic violence. Cove Recovery LLC is dedicated to personalized treatment plans and gender-responsive services, ensuring each individual receives high-quality, empathetic support on their journey to recovery.

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Covenant Hills Treatment Center, located in Capistrano Beach, CA, focuses on addressing substance abuse issues among adult women. The center offers a variety of programs including both long-term and short-term residential options, as well as 24-hour care, designed specifically for those dealing with both mental health challenges and substance use problems. Emphasizing 12-step methods, anger management techniques, and brief intervention strategies, Covenant Hills aims to provide targeted support for individuals with trauma histories. Their services are designed to assist a broad spectrum of clients, including adults, seniors, and young adults, ensuring that everyone receives the necessary help. The center's dedication to high-quality treatment and customized care makes it a reliable option for individuals pursuing effective addiction recovery solutions.

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Covenant Hills Treatment Center, situated in San Clemente, CA, specializes in providing long-term, residential, and short-term treatment programs for adult males struggling with substance use issues. The center emphasizes methodologies such as 12-step programs, anger management, and brief intervention strategies, specifically addressing the needs of individuals who have faced trauma and those dealing with co-occurring mental health and substance use challenges. Catering to a diverse clientele, including adults, seniors, and young adults, Covenant Hills Treatment Center is committed to creating a personalized recovery experience for every patient. Known for its high-quality care and customized treatment options, this facility stands out as a leading choice for those in search of thorough rehabilitation services within a nurturing setting.

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Spokane, WA

CPF Colonial in Spokane, WA, provides comprehensive outpatient and intensive outpatient programs for individuals of all ages struggling with substance use and co-occurring mental health conditions. Their therapeutic approach incorporates brief intervention, cognitive behavioral therapy, and motivational interviewing, ensuring personalized treatment plans for adult men and women, as well as adolescents. The center excels in supporting clients with dual diagnoses, serving both male and female populations. CPF Colonial stands out as a leading facility for those in the Spokane region requiring in-depth recovery services.

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Saint Paul, MN

"Create Inc," situated in Saint Paul, MN, provides extensive recovery care for adults and young adults struggling with substance use disorders. Their program offerings include intensive outpatient, outpatient, and standard outpatient services. Utilizing evidence-based approaches such as brief intervention, cognitive behavioral therapy, and motivational interviewing, "Create Inc" ensures personalized treatment plans. The center also features specialized care for adult men, adult women, and individuals with a history of trauma. "Create Inc" is dedicated to delivering excellent, gender-informed care to all clients, fostering a nurturing and expert environment for those pursuing successful, individualized addiction recovery.

Depression & Substance Use Disorder: Key Facts

Classification

Major Depressive Disorder + Substance Use Disorder (Dual Diagnosis)

Co-occurrence

~1 in 3 people with depression also have SUD (NIDA)

Prevalence

21 million adults with major depressive episode/year (NIMH)

Self-medication

Depression is the #1 reason for substance self-medication

Treatment approach

Integrated dual diagnosis (treat both simultaneously)

Key therapies

CBT, DBT, medication management, group therapy

Medications

SSRIs (non-addictive), SNRIs — safe during addiction treatment

Prognosis

Significantly better outcomes with integrated treatment vs sequential

If you or someone you know is experiencing suicidal thoughts, call 988 (Suicide & Crisis Lifeline) or text 988 immediately. Help is available 24/7.

Depression and Addiction: The Dual Diagnosis Connection

How depression and addiction feed each other

Depression and substance use disorder share a deeply intertwined relationship. Depression causes persistent feelings of emptiness, hopelessness, and emotional pain that drive many people toward alcohol or drugs as a form of self-medication. Substances may provide temporary relief, but they alter brain chemistry in ways that worsen depressive symptoms over time — creating a destructive cycle that accelerates both conditions.

The self-medication cycle

The self-medication cycle is the most common pathway from depression to addiction. A person experiencing persistent sadness, fatigue, or emotional numbness turns to alcohol, opioids, or stimulants to feel better temporarily. As tolerance builds, they need more of the substance to achieve the same relief. Meanwhile, the substance disrupts serotonin and dopamine regulation in the brain, deepening the depression. When the substance wears off, the depression returns worse than before — driving further substance use.

Why treating one without the other fails

Treating addiction without addressing underlying depression leaves the root cause intact. The person achieves sobriety but continues suffering from untreated depression, making relapse nearly inevitable as they seek relief. Conversely, treating depression without addressing active substance use is ineffective because ongoing drug or alcohol use undermines the neurochemical changes that antidepressants and therapy work to achieve. This is why dual diagnosis treatment — addressing both conditions simultaneously — produces significantly better outcomes than treating either condition alone.

Signs of Co-Occurring Depression and Substance Abuse

Recognizing co-occurring depression and substance abuse can be challenging because symptoms overlap. Watch for these warning signs:

Emotional and behavioral signs

  • Persistent sadness combined with increased substance use
  • Withdrawal from friends, family, and activities once enjoyed
  • Using drugs or alcohol specifically to cope with emptiness or hopelessness
  • Feelings of worthlessness or excessive guilt alongside substance use
  • Loss of motivation or interest in recovery efforts

Physical signs

  • Significant changes in sleep patterns — insomnia or oversleeping
  • Appetite and weight changes (loss or gain)
  • Chronic fatigue even with adequate rest
  • Increased substance tolerance requiring higher doses
  • Neglect of personal hygiene and self-care

How Dual Diagnosis Treatment Works

Integrated approach

Dual diagnosis treatment treats depression and addiction as interconnected conditions rather than separate problems. Instead of completing addiction treatment first and then addressing depression (the sequential approach that often fails), integrated programs work on both simultaneously. This means therapy sessions address how depressive thoughts drive substance use, while psychiatric care stabilizes mood to support sobriety.

Psychiatric evaluation during early sobriety

Accurate diagnosis of depression requires evaluation during a period of sobriety, because many substances can mimic or mask depressive symptoms. Alcohol is a depressant that causes sadness and lethargy. Stimulant withdrawal causes profound depression. A psychiatrist experienced in dual diagnosis will conduct thorough assessments during early sobriety to distinguish substance-induced mood changes from underlying major depressive disorder, ensuring the right treatment plan.

Coordinated care teams

Effective dual diagnosis programs use coordinated care teams where psychiatrists, addiction counselors, therapists, and medical staff communicate about each patient's progress. The psychiatrist managing antidepressant medication works closely with the addiction counselor guiding recovery, so treatment decisions account for both conditions. This prevents the common problem of one provider unknowingly undermining another's treatment plan.

Medication management alongside addiction treatment

One of the most important aspects of dual diagnosis care is safe medication management. Antidepressants like SSRIs and SNRIs are non-addictive and can be prescribed safely during addiction treatment. A psychiatrist monitors medication effectiveness, adjusts dosages, and watches for interactions — all while the person is actively working on recovery from substance use disorder.

Evidence-Based Therapies for Depression in Recovery

Cognitive Behavioral Therapy (CBT)

Cognitive Behavioral Therapy (CBT) is the gold standard for treating co-occurring depression and addiction. CBT helps identify negative thought patterns that drive both depressive episodes and substance use — such as "nothing will ever get better" or "I can't cope without drinking." Patients learn to challenge these distortions and replace them with realistic, constructive thinking. Research consistently shows CBT reduces both depressive symptoms and substance use relapse rates.

Dialectical Behavior Therapy (DBT)

Dialectical Behavior Therapy (DBT) is particularly effective for people with severe depression, emotional dysregulation, or self-harm behaviors alongside addiction. DBT teaches four core skill sets: mindfulness, distress tolerance, emotion regulation, and interpersonal effectiveness. These skills directly address the emotional pain that drives self-medication and provide healthier alternatives to substance use.

Group therapy

Group therapy combats the isolation that is central to both depression and addiction. Hearing others share similar struggles reduces shame and hopelessness. Dual diagnosis groups specifically address how depression and substance use interact, offering peer support from people who understand both conditions. Group settings also build social skills and accountability that support long-term recovery.

Medication management

Antidepressant medications are a critical component of treatment for many people with co-occurring depression and addiction. SSRIs (selective serotonin reuptake inhibitors) like sertraline and fluoxetine are first-line treatments because they are effective, well-tolerated, and — importantly — non-addictive. They carry no abuse potential and do not produce euphoria, making them safe to prescribe during addiction recovery. SNRIs like venlafaxine and duloxetine are also effective alternatives.

Levels of Care for Depression and Addiction

When residential treatment is needed

Residential treatment is recommended when depression is severe — particularly when suicidal ideation is present, when the person has made previous suicide attempts, or when outpatient treatment has failed. Residential programs provide 24/7 psychiatric monitoring, immediate medication adjustments, and a safe environment removed from triggers. People with severe addiction alongside major depression often need this level of structured support to stabilize both conditions.

Intensive Outpatient Programs (IOP)

Intensive Outpatient Programs provide 9–20 hours of structured therapy per week while allowing patients to live at home. IOP is appropriate for moderate depression with addiction, for people stepping down from residential care, or when the person has a stable living environment and support system. Dual diagnosis IOP programs include both addiction counseling and psychiatric services.

Outpatient care with medication management

Standard outpatient treatment works well for mild to moderate depression with substance use disorder, especially when combined with antidepressant medication. This typically involves weekly therapy sessions, regular psychiatric check-ins for medication management, and support group participation. Outpatient care allows people to maintain work, family, and daily responsibilities while receiving treatment.

Choosing the right level of care

The appropriate level of care depends on several factors: severity of depression (mild vs. severe with suicidal thoughts), severity of addiction, previous treatment attempts and outcomes, strength of social support, co-occurring medical conditions, and safety concerns. A professional assessment by a dual diagnosis specialist can determine the best starting point. Many people move through multiple levels of care as they progress in recovery.

Antidepressant Medications in Recovery

SSRIs: the first-line treatment

Selective serotonin reuptake inhibitors (SSRIs) such as sertraline (Zoloft), fluoxetine (Prozac), and escitalopram (Lexapro) are the most commonly prescribed antidepressants for people in addiction recovery. They work by increasing serotonin availability in the brain, gradually improving mood, sleep, and motivation over 4–6 weeks. SSRIs are not addictive, do not produce a high, and have no abuse potential — making them fundamentally different from the substances being treated.

SNRIs and bupropion

Serotonin-norepinephrine reuptake inhibitors (SNRIs) like venlafaxine (Effexor) and duloxetine (Cymbalta) target both serotonin and norepinephrine, which can be helpful for depression with prominent fatigue or chronic pain. Bupropion (Wellbutrin) is another option that acts on dopamine and norepinephrine — it can help with depression, low energy, and is also used to support smoking cessation. None of these medications carry addiction risk.

Addressing the stigma around psychiatric medication

Many people in recovery resist antidepressants because they feel taking any medication contradicts sobriety. This misconception is dangerous. Antidepressants are not mood-altering substances in the way drugs of abuse are — they restore normal brain chemistry rather than creating artificial highs. Untreated depression is one of the strongest predictors of addiction relapse. Taking prescribed, non-addictive medication to manage a medical condition is not a failure of recovery — it supports it.

Why stopping psychiatric meds leads to relapse

A common and harmful pattern occurs when people in recovery stop their antidepressants because they feel better, believe they no longer need them, or face pressure from others to be "medication-free." When depression returns — often within weeks — the emotional pain drives them back to substances. Antidepressant treatment for co-occurring depression should be maintained for at least 12 months after stabilization, and many people benefit from long-term maintenance. Any changes to psychiatric medication should be made gradually under medical supervision.

Frequently Asked Questions About Depression and Addiction

What is dual diagnosis treatment for depression and addiction?

Dual diagnosis treatment addresses both depression and substance use disorders simultaneously through integrated care. This approach recognizes that mental health and addiction affect each other and must be treated together for lasting recovery. Treatment includes psychiatric care, medication management, therapy (CBT, DBT), and specialized counseling that addresses both conditions comprehensively.

Can depression cause substance abuse?

Yes, depression significantly increases the risk of substance abuse. Many people self-medicate depression symptoms with alcohol or drugs, seeking temporary relief from emotional pain, low energy, or insomnia. However, substance use worsens depression long-term by disrupting serotonin and dopamine regulation, creating a vicious cycle. Proper treatment addresses root causes of depression while providing healthier coping strategies than substances.

Will antidepressants interfere with addiction treatment?

No, appropriate antidepressant medication actively supports recovery. Quality dual diagnosis programs work with psychiatrists to find effective antidepressant treatment while addressing addiction. Medications like SSRIs and SNRIs are non-addictive and help stabilize mood, making it easier to engage in therapy and maintain sobriety. Never stop psychiatric medications without medical guidance.

How do I find a treatment center for depression and addiction?

Look for centers explicitly offering dual diagnosis or co-occurring disorder treatment. Verify they have licensed mental health professionals, psychiatric services, medication management capabilities, and experience treating both conditions together. Use our directory to filter for dual diagnosis programs, read reviews, and verify accreditation. Contact admissions teams to discuss your specific needs.

Is residential treatment necessary for depression and addiction?

Not always. Treatment level depends on severity of both conditions, previous treatment attempts, safety concerns, and support system. Some people do well with intensive outpatient care plus medication management. Residential treatment provides 24/7 support for severe depression, suicide risk, or when outpatient treatment hasn't succeeded. A professional assessment determines the most appropriate level of care.

Can addiction cause depression or does depression cause addiction?

The relationship is bidirectional — it works both ways. Depression can lead to substance abuse through self-medication, as people use drugs or alcohol to escape emotional pain. At the same time, chronic substance use alters brain chemistry in ways that cause or worsen depression — alcohol is a central nervous system depressant, stimulant withdrawal causes profound depression, and opioid use disrupts the brain's natural mood regulation. In many cases, both conditions develop and reinforce each other simultaneously, which is why integrated dual diagnosis treatment is essential for lasting recovery.

Will I need antidepressants forever?

Not necessarily. Many people take antidepressants for 12–24 months after their mood stabilizes, then gradually taper off under medical supervision. However, some people with recurrent major depression (three or more episodes) benefit from long-term maintenance medication. The decision depends on depression severity, number of past episodes, family history, and individual response to treatment. What is critical is never stopping antidepressants abruptly — doing so can cause withdrawal symptoms and trigger relapse in both depression and addiction. Always work with your prescribing psychiatrist to make any medication changes.

Medical Review and Sources

Medically Reviewed Updated April 10, 2026

Reviewed by licensed addiction specialists. Information reflects current clinical guidance.

Sources:SAMHSA·NIDA·CDC

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