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Updated: May 2026
Sources: SAMHSA, NIDA

Suboxone Clinic Near You: Buprenorphine Treatment for Opioid Addiction

Find a Suboxone clinic near you. Buprenorphine — sold under brand names Suboxone, Sublocade, Subutex, Zubsolv, and Brixadi — is the most-prescribed MAT for opioid use disorder. It is a partial mu-opioid agonist with a ceiling effect that dramatically reduces overdose risk vs. methadone. After the MAT Act of 2023 eliminated the X-waiver requirement, any licensed prescriber can prescribe buprenorphine in office-based settings (OBOT), via telehealth, or at retail pharmacies. Buprenorphine is a Schedule III controlled substance and is covered by Medicaid in all 50 states.

Found 7,145 treatment centers offering buprenorphine (suboxone) across the United States.

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Aegis Treatment Centers LLC

Aegis Treatment Centers LLC in El Monte, CA, provides outpatient services for detox and addiction treatment. Their specialties include preventing future relapses, offering counseling for substance use disorders, and utilizing virtual therapy options. They have specific programs designed for active military members, adult men, and adult women. The center accommodates adults and young adults of all genders, emphasizing personalized care within a nurturing setting to support individuals on their journey to sobriety.

Aegis Treatment Centers LLC

Aegis Treatment Centers LLC, located in Bakersfield, CA, provides comprehensive outpatient services for individuals struggling with substance use. Their offerings encompass medication-assisted treatment with methadone, buprenorphine, or naltrexone, alongside standard outpatient counseling. Specialized therapies, such as anger management, brief intervention, and cognitive behavioral therapy, are also available. The center serves a diverse clientele, including active duty military members, adult men, and adult women, with a particular focus on providing individualized support to adults and young adults of all genders. Aegis Treatment Centers LLC in Bakersfield is dedicated to delivering high-quality, evidence-based care to promote successful recovery journeys.

Aegis Treatment Centers LLC

Nestled in Redding, CA, Aegis Treatment Centers LLC provides comprehensive outpatient care, including substance use disorder treatment and medication-assisted therapy with methadone, buprenorphine, or naltrexone. Their expertise extends to specialized programs such as anger management, brief intervention, and cognitive behavioral therapy. Aegis Treatment Centers LLC is committed to serving diverse populations, offering tailored services for adult men, adult women, pregnant and postpartum women, and young adults. They foster a nurturing atmosphere for both male and female adults pursuing recovery. Aegis Treatment Centers LLC utilizes scientifically-backed methods to empower individuals on their journey to sobriety, standing as a symbol of accessible and individualized recovery solutions.

Aegis Treatment Centers LLC

Aegis Treatment Centers LLC in Ventura, CA, provides outpatient services for adults and young adults to address substance use disorders. They offer specialized programs for active military personnel, adult men, and adult women, ensuring care is customized to individual requirements. Their treatment methods include 12-step facilitation, anger management, and brief intervention, all aimed at promoting comprehensive recovery. Aegis Treatment Centers LLC, which serves both genders, is dedicated to high-quality, personalized treatment plans designed to aid in successful recovery. For those in Ventura looking for thorough addiction treatment, this center offers evidence-based care and supportive assistance.

Aegis Treatment Centers LLC

Aegis Treatment Centers LLC in Bakersfield, CA, delivers outpatient services for individuals struggling with substance use disorders. Their offerings include medication-assisted treatment utilizing methadone, buprenorphine, or naltrexone. The center employs evidence-based therapeutic modalities such as 12-step program support, anger management techniques, and brief intervention strategies. Aegis Treatment Centers LLC is dedicated to serving specific populations, including active military personnel, adult men, and adult women, with tailored programs. They welcome adults and young adults of all genders seeking effective recovery solutions. The facility is committed to providing excellent care and robust support for those on their journey to sobriety.

Aegis Treatment Centers LLC

Aegis Treatment Centers LLC in Chico, CA, is a premier establishment dedicated to assisting adults and young adults in overcoming substance dependency. Their services encompass outpatient treatment utilizing methadone, buprenorphine, or naltrexone, along with standard outpatient programs. They also employ specialized strategies like contingency management, the Matrix Model, and motivational interviewing to craft individualized care. Aegis Treatment Centers LLC offers specific support for active duty military members, as well as separate programs for adult men and adult women. The center distinguishes itself through its commitment to personalized treatment frameworks and scientifically validated therapeutic methods, ensuring high standards of care for all clients, regardless of gender.

Aegis Treatment Centers LLC

Aegis Treatment Centers LLC in Hesperia, CA, delivers outpatient care for individuals grappling with substance use disorders and co-occurring mental health conditions. The program encompasses outpatient medication-assisted treatment utilizing methadone, buprenorphine, or naltrexone, supported by proven therapeutic methods like 12-step program integration, anger management techniques, and brief counseling strategies. Personalized treatment plans are available for both adults and young adults, acknowledging their unique needs. Aegis Treatment Centers LLC is committed to providing high-quality, all-encompassing assistance to guide individuals toward sustained sobriety and well-being. For those in need of effective addiction support in a supportive setting, Aegis Treatment Centers LLC in Hesperia is a viable option.

Aegis Treatment Centers LLC

Aegis Treatment Centers LLC, located in Marysville, CA, delivers outpatient services for chemical dependency and substance abuse, serving adults and adolescents. The center features targeted interventions for expectant and new mothers, with distinct care plans for male and female patients. Employing therapeutic modalities such as cognitive behavioral therapy, motivational incentives, and the Matrix Model, Aegis Treatment Centers LLC prioritizes scientifically supported methods for successful rehabilitation. The facility also provides outpatient medication-assisted treatment using methadone, buprenorphine, or naltrexone, addressing a broad spectrum of recovery requirements. For those in Marysville requiring thorough and individualized addiction recovery support, Aegis Treatment Centers LLC is committed to guiding individuals toward sustained wellness.

Aegis Treatment Centers LLC

Aegis Treatment Centers LLC, located in Atascadero, CA, specializes in outpatient services for substance abuse and co-occurring mental health conditions in adults, and emotional disturbances in children. Their treatment methods include 12-step facilitation, anger management, and brief intervention strategies to deliver thorough support. The center offers distinct programs for active duty military, adult men, and women, acknowledging varied requirements. Aegis is committed to providing personalized and high-quality care to adults and young adults of all genders, making it a trusted option for those pursuing effective and caring addiction recovery in Atascadero.

Aftermath Addiction Treatment Ctr LLC

Aftermath Addiction Treatment Center LLC, located in Wakefield, MA, provides extensive services for adult individuals struggling with substance use issues, particularly those facing concurrent mental health disorders. The center extends its support to children with significant emotional challenges as well. A range of treatment options is available, such as intensive outpatient, outpatient, and day treatment programs. Emphasizing models like 12-step support, cognitive behavioral therapy, and motivational interviewing, Aftermath designs customized treatment plans to meet individual requirements. Specialized programs are offered for active military members, as well as tailored services for both adult men and women. This facility caters to adults and young adults of all genders, ensuring that quality care and individualized treatment methods are at the forefront of their mission to aid individuals in their recovery process.

Aegis Treatment Centers LLC

Aegis Treatment Centers LLC, located in Delano, CA, provides comprehensive outpatient services for individuals battling substance use disorders. Their programs encompass detoxification and ongoing treatment, serving both adult and adolescent populations. With expertise in anger management techniques, cognitive behavioral therapy, and the structured Matrix Model, Aegis Treatment Centers LLC welcomes clients of all genders. They also offer tailored support for expectant and new mothers, as well as those involved with the criminal justice system. The center is committed to delivering high-quality, personalized care designed to facilitate lasting recovery. Aegis Treatment Centers LLC is a suitable option for those in need of outpatient treatment utilizing methadone, buprenorphine, or naltrexone within a nurturing setting.

Aegis Treatment Centers LLC

Aegis Treatment Centers LLC, located in Grass Valley, CA, specializes in outpatient services for adults and young adults seeking to recover from substance use disorders. Their program includes medication-assisted treatment with methadone, buprenorphine, or naltrexone, complemented by therapeutic interventions such as 12-step support, anger management techniques, and brief counseling. The center is particularly attentive to the needs of pregnant and postpartum women, serving both male and female individuals. Aegis Treatment Centers LLC is committed to delivering effective and compassionate care within a supportive and professional setting for those pursuing sobriety.

Aegis Treatment Centers LLC

Aegis Treatment Centers LLC in Oxnard, CA, specializes in outpatient care for adults and young adults struggling with substance use. The center provides medication-assisted treatment, including methadone, buprenorphine, and naltrexone, alongside therapeutic interventions like 12-step facilitation, anger management, and brief intervention strategies. Aegis Treatment Centers LLC in Oxnard offers targeted programs for active duty military personnel, men, and women, ensuring a supportive and inclusive environment for all clients. Their approach emphasizes personalized treatment plans and specialized programs to guide individuals toward lasting recovery.

Affinity Healthcare Group Cherry Hill

Affinity Healthcare Group Cherry Hill, situated in Cherry Hill, NJ, provides a range of outpatient services including detoxification, comprehensive substance use disorder treatment, and medication-assisted treatment options such as methadone, buprenorphine, and naltrexone. This facility is equipped to assist both adults and young adults. Their specialized therapeutic approaches include anger management, brief intervention strategies, and cognitive behavioral therapy. A particular focus is placed on delivering personalized care for adult women, with programs designed to address their unique recovery journeys. The center welcomes both male and female clients, reflecting a holistic philosophy in addiction recovery. Affinity Healthcare Group Cherry Hill is committed to delivering excellent care and supportive services to those striving to recover from addiction.

Aeschbach and Associates Inc

Aeschbach and Associates Inc. in Austin, TX offers thorough outpatient care for those needing detox and help with substance use. They have expertise with dual diagnoses and provide outpatient detox and medication-assisted treatment options. Their programs include anger management, brief counseling, and cognitive behavioral therapy, specifically designed for adult women who have experienced intimate partner violence, domestic abuse, or sexual assault. They welcome adults and younger individuals of any gender, delivering personalized, evidence-based support for their recovery journey.

Affect Therapeutics

Affect Therapeutics, situated in Ballwin, MO, provides outpatient treatment for substance use disorders aimed at both adults and young adults. The center employs targeted methods including contingency management, motivational interviewing, and the Matrix Model to ensure specialized care. Prioritizing personalized treatment plans, Affect Therapeutics customizes its programs to address the diverse requirements of each individual. In addition to standard outpatient services, the facility offers methadone/buprenorphine or naltrexone treatment, ensuring a holistic approach to recovery. Catering to both men and women, Affect Therapeutics is dedicated to offering high-quality care in a nurturing setting, making it a prime option for those in need of effective and tailored addiction recovery solutions.

Affiliated Counseling Center Inc

Affiliated Counseling Center Inc, located in Beaver Dam, WI, provides outpatient care for substance abuse and tailored support for those facing co-occurring serious mental health challenges. Their services include outpatient treatment with methadone, buprenorphine, or naltrexone, alongside general outpatient programs. Emphasizing 12-step facilitation, anger control, and brief intervention, the center serves active military, teens, and adult men. They accommodate both adults and younger individuals, accepting both male and female patients. Affiliated Counseling Center Inc is a reliable provider of thorough and impactful recovery services.

Affinity Recovery
Desert Hot Springs, CA

Affinity Recovery, located in Desert Hot Springs, CA, provides extensive care for adults and young adults grappling with addiction. Their offerings include inpatient detox, short-term inpatient stays, and round-the-clock residential treatment. Emphasizing 12-step principles, anger management techniques, and brief intervention strategies, this establishment is well-equipped to assist those with dual diagnoses of substance abuse and significant mental health challenges. Specialized tracks are offered for adult men and women, as well as for survivors of intimate partner or domestic abuse. Affinity Recovery is dedicated to delivering superior treatment and encouragement to individuals pursuing sobriety within a secure and supportive setting.

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Situated in Portland, OR, Affect Therapeutics provides outpatient treatment for substance use specifically designed for both adults and young adults. The facility offers specialized outpatient services that include methadone/buprenorphine or naltrexone therapy, along with standard outpatient care. Employing proven methods like contingency management/motivational incentives, the Matrix Model, and motivational interviewing, they guarantee a thorough and customized treatment experience. Affect Therapeutics distinguishes itself through its commitment to individualized care, accommodating clients of all genders. For those in need of effective and empathetic addiction treatment, this center is committed to aiding your path to recovery.

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New Berlin, WI

Affect Therapeutics in New Berlin, WI, is a dedicated facility providing expert care for individuals grappling with substance use disorders and co-occurring mental health conditions, catering to both adults and youth. They offer robust intensive outpatient and outpatient services, incorporating medication-assisted treatments such as methadone, buprenorphine, and naltrexone to support recovery. Employing proven therapeutic modalities, including Contingency Management, the Matrix Model, and Motivational Interviewing, the center prioritizes crafting personalized treatment strategies. Affect Therapeutics welcomes adults and young adults of all gender identities, distinguishing itself through its customized programs and unwavering dedication to high-quality, individual-focused recovery support. If you are in search of impactful and personalized addiction treatment, Affect Therapeutics is committed to guiding you toward lasting recovery.

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Affect Therapeutics Inc, situated in Geneva, IL, delivers extensive outpatient substance use disorder care for adults and young adults. The facility offers tailored medication-assisted treatment with methadone, buprenorphine, or naltrexone, complementing standard outpatient services. Employing proven methods like contingency management, the Matrix Model, and motivational interviewing, Affect Therapeutics Inc personalizes its treatment plans. Committed to an individualized strategy, they provide high-quality care for all clients. For those looking for effective and customized addiction recovery support, this Geneva-based center is committed to aiding your path to wellness.

Frequently Asked Questions

What is buprenorphine and how does it treat opioid addiction?
Buprenorphine is a partial opioid agonist medication approved by the FDA for treating opioid use disorder. It binds to the same receptors as heroin and fentanyl but produces a much weaker effect, reducing cravings and withdrawal symptoms without causing intense euphoria. Buprenorphine has a ceiling effect, meaning its opioid effects plateau at moderate doses, making it safer than methadone in terms of overdose risk.
What is the difference between Suboxone and Subutex?
Suboxone contains two active ingredients — buprenorphine and naloxone — while Subutex contains only buprenorphine without naloxone. The naloxone in Suboxone is included as an abuse deterrent; it remains inactive when taken sublingually as prescribed but triggers withdrawal if the medication is injected. Subutex is generally reserved for patients who cannot tolerate naloxone, such as pregnant women.
What is a Sublocade injection and how does it work?
Sublocade is a once-monthly injectable form of buprenorphine administered as a subcutaneous injection in the abdominal area. After injection, the medication forms a solid deposit under the skin that slowly releases buprenorphine over the course of a month. This eliminates daily dosing and removes the possibility of missed doses or medication diversion.
What are the common side effects of Suboxone?
Common Suboxone side effects include headache, nausea, constipation, insomnia, sweating, and mouth numbness or pain from sublingual administration. Some patients also experience dizziness, drowsiness, and blurred vision, particularly when starting treatment. Most side effects diminish within the first few weeks as the body adjusts. Patients should report difficulty breathing or signs of allergic reaction immediately.
What happens during Suboxone withdrawal?
Suboxone withdrawal occurs when a patient stops taking the medication abruptly after prolonged use, with symptoms including muscle aches, anxiety, insomnia, nausea, and irritability. A medically supervised taper is strongly recommended, typically reducing the dose by small increments over weeks or months. The risk of opioid relapse is significantly higher during unsupervised discontinuation.
How does Suboxone compare to methadone?
Suboxone and methadone are both effective for opioid use disorder but differ in key ways. Methadone is a full opioid agonist dispensed daily at licensed clinics, while Suboxone is a partial agonist that can be prescribed by qualified physicians and taken at home. Suboxone carries a lower overdose risk due to its ceiling effect and offers greater convenience, though methadone may be more appropriate for patients with severe, long-standing dependence.
How can I find a Suboxone clinic or doctor near me?
The most reliable way to find a Suboxone provider is through SAMHSA's online treatment locator at findtreatment.gov, which allows you to search by location and filter for buprenorphine providers. Many primary care offices, addiction treatment centers, and telehealth platforms now offer Suboxone prescriptions following the elimination of the federal X-waiver requirement in early 2023.
What is Zubsolv and how is it different from Suboxone?
Zubsolv is a brand-name buprenorphine and naloxone sublingual tablet that features a mint flavor and dissolves faster under the tongue than other options. Due to its higher bioavailability, Zubsolv uses different dosing strengths — a Zubsolv 5.7 mg/1.4 mg tablet is considered equivalent to a Suboxone 8 mg/2 mg dose. Patients switching between products should work closely with their prescriber for correct dose conversion.
Does Medicaid cover Suboxone treatment?
Yes — Medicaid covers buprenorphine (including Suboxone, Sublocade, Subutex, Zubsolv, and Brixadi) for opioid use disorder in all 50 states, as required by the SUPPORT Act of 2018. Medicaid is the largest single payer for MAT in the US. Coverage details vary by state — some require prior authorization or limit certain formulations. Many OBOT clinics accept Medicaid directly; telehealth Suboxone providers also bill Medicaid in most states. Bring your Medicaid card to your intake appointment.
Can I get Suboxone through telehealth?
Yes. After the MAT Act of 2023 permanently eliminated the X-waiver requirement, any licensed prescriber can prescribe Suboxone via telehealth in most states. The DEA also extended COVID-era telehealth flexibilities through at least 2025, allowing virtual Suboxone induction without a prior in-person visit. Several specialty platforms — Bicycle Health, Ophelia, Workit Health, Boulder Care — offer Medicaid-accepting telehealth Suboxone treatment. Telehealth has dramatically expanded access in rural and underserved areas with no nearby OBOT physicians.

About Buprenorphine (Suboxone)

Buprenorphine is classified as a partial opioid agonist, meaning it activates opioid receptors in the brain but to a much lesser degree than full agonists such as heroin, fentanyl, or oxycodone. This partial activation suppresses withdrawal symptoms and reduces cravings without producing dangerous respiratory depression or intense euphoria. Buprenorphine also has an unusually high binding affinity for the mu-opioid receptor, effectively blocking other opioids from attaching — providing a protective effect against relapse-related overdose.

How Buprenorphine Works

One of the defining features of buprenorphine is its ceiling effect — after a certain dose threshold, increasing the amount does not produce additional opioid effects. This dramatically reduces the risk of fatal overdose compared to methadone or illicit opioids. The ceiling effect, combined with its long duration of action (24 to 72 hours), makes buprenorphine one of the safest and most effective tools in medication-assisted treatment (MAT). Approved by the FDA in 2002, buprenorphine was a breakthrough because it could be prescribed in outpatient settings rather than requiring daily clinic visits.

Buprenorphine Brand Comparison: Suboxone, Subutex, Sublocade, Zubsolv, Brixadi

Buprenorphine is available under several FDA-approved brand names, each with distinct formulations, dosing schedules, and clinical use cases. The comparison below highlights the key differences:

BrandActive ingredientFormFrequencySettingFDA yearBest for
SuboxoneBuprenorphine + naloxoneSublingual film / tabletDailyOBOT, telehealth, retail pharmacy2002Most prescribed; naloxone deters injection misuse
SubutexBuprenorphine (alone)Sublingual tabletDailyOBOT2002Pregnancy; documented naloxone sensitivity
SublocadeBuprenorphine extended-releaseSubcutaneous injection (ATRIGEL depot)MonthlyClinic-administered2017No daily dosing; eliminates diversion risk
ZubsolvBuprenorphine + naloxoneSublingual tablet (higher bioavailability)DailyOBOT2013Faster dissolution; mint flavor; lower mg/dose
BrixadiBuprenorphine extended-releaseSubcutaneous injectionWeekly or monthlyClinic2023Newer alternative to Sublocade; weekly option for induction

All five medications are Schedule III controlled substances and equivalent in clinical efficacy at appropriate doses. The choice depends on adherence patterns, lifestyle, insurance coverage, and clinical context (e.g., pregnancy, prior injection use, daily-dosing burden). Many patients begin on sublingual Suboxone for stabilization and transition to monthly Sublocade or weekly Brixadi after sustained recovery.

Buprenorphine Side Effects

Common buprenorphine side effects include:

  • Headache and dizziness
  • Nausea and vomiting, especially during induction
  • Constipation and insomnia
  • Excessive sweating
  • Mouth numbness or oral discomfort from sublingual formulations

More serious side effects may include respiratory depression (particularly when combined with benzodiazepines or alcohol), liver problems, and allergic reactions. For most patients, side effects are mild and resolve within one to two weeks. The benefits in preventing relapse and overdose death significantly outweigh the risks.

Buprenorphine Dosage and Induction

Treatment begins with an induction phase where the patient must be in mild to moderate opioid withdrawal. Common induction doses range from 2 mg to 8 mg on the first day, with increases over the following days. Most patients stabilize on 8 mg to 24 mg per day, with 16 mg being the most commonly prescribed dose. Research suggests doses of 16 mg or higher are associated with better retention and outcomes. Dosage should always be adjusted under medical supervision.

Buprenorphine/Naloxone Combination

Many buprenorphine formulations include naloxone as an abuse deterrent. When taken sublingually as directed, naloxone has very low bioavailability and produces no clinical effect. However, if someone attempts to inject the medication, the naloxone component becomes fully active and triggers severe withdrawal. This design discourages injection misuse while having no impact on patients who take the medication correctly. The combination is the standard first-line formulation for opioid addiction treatment.

Suboxone: Sublingual Buprenorphine

Suboxone is the most recognized brand name for buprenorphine-naloxone and is most commonly dispensed as a sublingual film (Suboxone strips) that dissolves under the tongue. Suboxone has transformed opioid treatment by enabling millions of patients to receive effective pharmacotherapy in outpatient settings without the daily clinic visits required by methadone programs.

Suboxone Side Effects

Commonly reported Suboxone side effects include headache, nausea, tongue or mouth irritation, constipation, insomnia, sweating, and decreased libido. The sublingual film can cause irritation or small sores inside the mouth — rotating placement between under the tongue and against the cheek helps minimize this. Patients should not eat, drink, or smoke while the film is dissolving.

Suboxone Strips: Film vs. Tablet

Suboxone strips (sublingual film) have largely replaced the original tablet form. The film dissolves more quickly (two to four minutes), provides more consistent absorption, and is harder to divert due to individual foil packaging. Generic buprenorphine-naloxone tablets are often less expensive and may be preferred for cost reasons. Both are therapeutically equivalent when taken as prescribed.

Suboxone Treatment Programs

Comprehensive Suboxone treatment typically includes three phases:

  • Induction: Initial dosing under medical supervision, requiring the patient to be in early withdrawal
  • Stabilization: Dose adjustment until cravings and withdrawal are minimal, usually one to two months
  • Maintenance: Stable dosing for an extended period — often a year or longer — combined with counseling and behavioral therapy

Evidence consistently shows that longer treatment durations are associated with better outcomes. Most addiction medicine experts recommend a minimum of one to two years of maintenance therapy.

Find a Suboxone Clinic Near You — OBOT & Telehealth Options

Finding a Suboxone clinic has become significantly easier since the federal government eliminated the X-waiver requirement in January 2023, meaning any provider with a standard DEA license can now prescribe Suboxone. Patients can search SAMHSA's treatment locator at findtreatment.gov or use our directory to locate nearby facilities that offer buprenorphine-based treatment.

Suboxone Doctors Near Me

Beyond SAMHSA's locator, many state health departments maintain directories of addiction treatment providers. Telehealth has dramatically expanded access — several platforms now offer virtual Suboxone consultations, which is especially valuable for patients in rural areas. When selecting a provider, look for those offering comprehensive treatment including counseling, not just medication prescriptions.

Suboxone Withdrawal and Tapering

Suboxone withdrawal can include muscle aches, anxiety, insomnia, nausea, sweating, and intense opioid cravings. A gradual, medically supervised taper is recommended — typically reducing the dose by 10 to 25 percent every one to four weeks. Slower tapers over several months produce fewer symptoms and lower relapse rates. There is no medically mandated time limit for Suboxone treatment, and many patients benefit from indefinite maintenance.

Suboxone vs Methadone

Suboxone can be prescribed in office settings and taken at home, carries lower overdose risk due to its ceiling effect, and offers greater scheduling flexibility. Methadone is a full agonist that may be more effective for severe, long-standing dependence but must be dispensed at licensed clinics with daily visits. Neither is inherently superior — the best choice keeps the patient in treatment. Some patients may also benefit from naltrexone, a non-opioid alternative.

Sublocade: Monthly Buprenorphine Injection

Sublocade delivers buprenorphine as a once-monthly subcutaneous injection in the abdominal area using the ATRIGEL delivery system, which forms a solid biodegradable depot that slowly releases medication. Patients must first stabilize on sublingual buprenorphine (8 mg+ daily) for at least seven days. Treatment typically begins with two 300 mg injections, followed by maintenance on 300 mg or 100 mg. Sublocade eliminates concerns about daily adherence, missed doses, and medication diversion.

Sublocade Side Effects

The most common Sublocade side effects are injection-site reactions (pain, itching, redness, or a noticeable lump), nausea, constipation, headache, and fatigue. The injection-site lump is normal and gradually diminishes as medication is absorbed. Patients should avoid rubbing or massaging the site. Elevated liver enzymes may also occur but are usually mild and transient.

Subutex: Buprenorphine Without Naloxone

Subutex was the original brand-name buprenorphine product. While the brand has been discontinued, generic buprenorphine-only tablets remain available. Buprenorphine monotherapy is typically reserved for pregnant patients (to avoid naloxone exposure to the fetus), patients with documented naloxone sensitivity, or sometimes during the induction phase before transitioning to the combination product.

Subutex vs Suboxone

The primary difference is the absence of naloxone in Subutex. Because Subutex lacks the abuse-deterrent naloxone component, it may carry slightly higher diversion risk, and many insurance formularies prioritize the combination as the default. Current clinical guidelines favor buprenorphine-only formulations primarily for pregnancy and naloxone sensitivity.

Zubsolv: Alternative Buprenorphine Brand

Zubsolv is a buprenorphine-naloxone sublingual tablet featuring a mint flavor and faster dissolution (under two minutes). Due to enhanced bioavailability, Zubsolv uses different dose strengths — a 5.7 mg/1.4 mg tablet equals a Suboxone 8 mg/2 mg dose. Zubsolv is available in multiple strengths for flexible dosing during both induction and maintenance.

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Medically Reviewed Updated May 2026

Reviewed by licensed addiction specialists. Information reflects current clinical guidance.

Sources:SAMHSA·NIDA·CDC

Need immediate help? Call SAMHSA: 1-800-662-4357 (24/7, free)