NWVCIL Logo
Medically Reviewed Content
Updated: May 2026
Sources: SAMHSA, NIDA

Suboxone Clinic Near You: Buprenorphine Treatment for Opioid Addiction

Find a Suboxone clinic near you. Buprenorphine — sold under brand names Suboxone, Sublocade, Subutex, Zubsolv, and Brixadi — is the most-prescribed MAT for opioid use disorder. It is a partial mu-opioid agonist with a ceiling effect that dramatically reduces overdose risk vs. methadone. After the MAT Act of 2023 eliminated the X-waiver requirement, any licensed prescriber can prescribe buprenorphine in office-based settings (OBOT), via telehealth, or at retail pharmacies. Buprenorphine is a Schedule III controlled substance and is covered by Medicaid in all 50 states.

Found 7,145 treatment centers offering buprenorphine (suboxone) across the United States.

Need Help Finding the Right Treatment Center?

Speak with a compassionate specialist now - 100% free & confidential

Call +1 (833) 244-3031
Available 24/7
All 50 States
Filters:

Showing 21 of 7145 results

Alcohol and Drug Awareness Center

The Alcohol and Drug Awareness Center, situated in San Angelo, TX, is a facility dedicated to providing thorough addiction recovery programs. Their expertise encompasses safe detoxification and extensive substance use disorder treatment, offering extended stays in a residential setting with constant professional oversight. The treatment regimen incorporates proven methodologies such as 12-step program integration, cognitive behavioral techniques, and motivational interviewing. The center provides specialized tracks for adult men, adult women, and individuals involved with the legal system, ensuring each client receives care suited to their unique circumstances. Open to adults and young adults of any gender, this center is committed to delivering high-caliber treatment and customized recovery strategies aimed at achieving sustained sobriety.

Aleda E Lutz VAMC

Situated in Saginaw, MI, the Aleda E Lutz VAMC stands out as a premier rehabilitation center dedicated to assisting adults and young adults facing challenges related to substance use and accompanying mental health conditions. The center features both intensive outpatient and outpatient detox programs, employing proven methods including cognitive behavioral therapy and anger management techniques. With a particular emphasis on adult women, survivors of domestic violence, and those who have faced sexual abuse, this facility provides customized support for its clients. Both men and women can access a range of comprehensive treatment solutions that emphasize high-quality, compassionate care.

Aldie Counseling Center

Nestled in Doylestown, PA, Aldie Counseling Center distinguishes itself with comprehensive programs for individuals of all ages grappling with substance use disorders and co-occurring mental health conditions. The center emphasizes intensive outpatient and standard outpatient services, employing evidence-based therapies like 12-step facilitation, cognitive behavioral therapy, and brief intervention strategies. Aldie Counseling Center offers specialized support for active duty military members, teenagers, and adult men, ensuring a gender-inclusive approach to recovery for both male and female clients facing addiction and mental health struggles.

Alchemy Addiction Recovery

Alchemy Addiction Recovery in Slidell, LA, delivers a full spectrum of treatment options for adults and young adults struggling with addiction. Their offerings include intensive outpatient care, outpatient detoxification services, and structured outpatient programs. The center emphasizes proven therapeutic modalities such as 12-step facilitation, anger management techniques, and brief intervention strategies. They are equipped to support individuals facing dual diagnoses of mental health and substance use disorders, as well as those managing pain-related issues. Alchemy Addiction Recovery welcomes both male and female patients, providing gender-sensitive treatment approaches. Discover effective and personalized recovery support at this respected addiction treatment facility.

Alchemy Addiction Recovery

Alchemy Addiction Recovery, situated in Metairie, LA, delivers extensive support for those battling addiction. This center is dedicated to aiding adults and young adults through detox and substance use therapy. Their commitment to superior treatment includes structured outpatient care, general outpatient services, and detox administered on an outpatient basis. Alchemy Addiction Recovery utilizes proven methods such as 12-step integration, emotional regulation techniques, and motivational interviewing to foster healing. They also offer specialized care for individuals facing dual diagnoses of mental health and addiction, as well as those managing chronic pain alongside substance use disorders. Alchemy Addiction Recovery serves both men and women, fostering a safe and encouraging space for everyone on their path to wellness.

Aletheia House
Birmingham, AL

Aletheia House, situated in Birmingham, Alabama, delivers a wide range of substance abuse rehabilitation options, including intensive outpatient programs, outpatient services, and standard outpatient care. This center features targeted programs designed specifically for adult males, individuals who have faced trauma, and those living with HIV or AIDS. Emphasizing techniques such as anger management, cognitive behavioral therapy, and motivational incentives, Aletheia House serves adults and young adults of every gender. The facility is committed to providing exceptional, personalized care, establishing itself as a crucial support system for individuals in need of effective addiction recovery services.

Aletheia House
Birmingham, AL

Aletheia House, situated in Birmingham, AL, delivers comprehensive substance abuse rehabilitation within a long-term residential environment, serving adult males exclusively. This facility provides tailored interventions for individuals managing HIV or AIDS, and those navigating the legal system. Employing proven therapeutic modalities such as anger management, cognitive behavioral therapy, and contingency management, the center customizes treatment plans for each resident. Catering to adult, senior, and young adult men, Aletheia House ensures round-the-clock residential care to foster enduring recovery.

Alcohol and Drug Dep Services of SE IA

Situated in Burlington, IA, the Alcohol and Drug Dep Services of SE IA presents a wide variety of treatment solutions for those struggling with substance use disorders. This center features intensive outpatient programs, extended residential care, and outpatient services. Employing evidence-based techniques such as cognitive behavioral therapy, motivational interviewing, and contingency management, the facility serves adolescents, adult males, adult females, along with older adults. With tailored programs for various age groups and genders, the center guarantees personalized attention. Clients can look forward to receiving quality support and care as they navigate their recovery journey, whether they need transitional housing, a halfway house, or a sober living environment.

Alcohol and Drug Freedom Center of

Situated in Mount Vernon, OH, the Alcohol and Drug Freedom Center delivers an extensive array of substance use disorder treatment for both adults and children facing simultaneous mental health challenges. The center offers various treatment modalities, including intensive outpatient, outpatient, and medications like methadone and buprenorphine. Employing a mix of strategies, such as cognitive behavioral therapy and community reinforcement with vouchers, it serves a diverse clientele, including adults, seniors, and specialized programs for teens, as well as men and women. With an emphasis on anger management and personalized care for each gender, this facility is dedicated to providing high-quality, customized support for individuals pursuing recovery from addiction.

Placeholder image

Situated in Muskegon, MI, Alcohol and Chemical Abuse Consultants offers focused treatment for individuals dealing with substance use issues, encompassing both adults and young adults. The center provides outpatient services that include methadone and buprenorphine therapies, emphasizing cognitive behavioral strategies, motivational techniques, and methods for preventing relapse. With an individualized approach, this facility serves both men and women. Its commitment to high-quality care and all-encompassing treatment strategies positions it as an excellent option for anyone in need of effective addiction recovery solutions. For those in search of customized outpatient care within a nurturing atmosphere, this center is dedicated to supporting clients on their path to sustainable recovery.

Placeholder image

The Alcohol and Drug Council Tompkins Cnty, situated in Ithaca, NY, delivers outpatient services for individuals navigating substance use challenges. Their approach incorporates evidence-based methods such as cognitive behavioral therapy, motivational interviewing, and relapse prevention techniques. The center accommodates a broad spectrum of individuals, with distinct programs designed for young people, adult men, and adult women. They extend their care across all age demographics, from adults and youth to seniors, and provide gender-specific treatment pathways to foster tailored support. This dedication to effective, personalized care establishes the facility as a vital provider for those striving for recovery.

Placeholder image

Situated in Mount Pleasant, IA, Alcohol and Drug Dep Services of SE IA provides outpatient programs designed for individuals dealing with substance use issues, specifically aimed at adults and seniors. This center offers tailored care for both men and women, utilizing various treatment methodologies such as cognitive behavioral therapy, motivational interviewing, and contingency management. Additionally, the facility includes outpatient options for methadone/buprenorphine or naltrexone therapy. With a commitment to delivering high-quality care, this center supports clients of all genders in their pursuit of effective and customized addiction recovery solutions.

Placeholder image

Alcohol and Drug Dep Services of SE IA, situated in Keokuk, IA, delivers extensive substance abuse care for adults and older adults. Their services include outpatient treatment with methadone, buprenorphine, or naltrexone, alongside regular outpatient programs. They employ proven methods like cognitive behavioral therapy, motivational interviewing, and contingency management. Tailored services are available for adult men and women, recognizing gender-specific requirements. Prioritizing high-quality assistance, the center crafts personalized recovery strategies. For those needing effective addiction treatment, this establishment offers a nurturing setting for healing and rehabilitation.

Placeholder image

Alcohol and Drug Services (ADS) located in Greensboro, NC, provides a wide range of treatment options for adults dealing with substance use issues, as well as those who may have concurrent mental health challenges. The center’s offerings extend to address serious mental health concerns and emotional issues impacting children. ADS features intensive outpatient programs, standard outpatient care, and specialized services specifically for pregnant or postpartum women. The center employs methods such as 12-step facilitation and cognitive behavioral therapy to ensure personalized care based on evidence-based practices. With a solid focus on clients with dual diagnoses, ADS is committed to delivering customized support to meet each individual’s specific requirements. Catering to both adult men and women, along with young adults, this facility is devoted to offering exceptional and compassionate support for individuals embarking on their journey to recovery from addiction.

Placeholder image
Mandeville, LA

Situated in Mandeville, LA, the Alcohol and Drug Unit delivers exceptional treatment for substance use disorders aimed at both adults and young adults. Emphasizing the importance of co-occurring mental health conditions, this center offers targeted support for those with psychological challenges. Its programs feature anger management, cognitive behavioral therapy, and short-term intervention techniques. Designed for adult males and those involved with the criminal justice system, the center provides 24-hour residential care as well as short-term options to deliver thorough assistance. Demonstrating a dedication to high-quality treatment, this facility serves both men and women pursuing successful rehabilitation.

Placeholder image

Alcohol/Drug Care Services Inc, located in Eureka, CA, provides extensive addiction recovery services for both adults and young adults. Focused on detoxification, treatment for substance use disorders, and addressing co-occurring conditions, this center offers long-term residential support with round-the-clock assistance. Employing techniques like 12-step facilitation, anger management, and brief intervention, the facility customizes its care to meet the unique needs of each client. There are specialized programs designed for individuals who have experienced intimate partner violence, sexual abuse, and trauma. Committed to delivering high-quality care, Alcohol/Drug Care Services Inc accommodates male and female clients, offering tailored, gender-specific recovery support.

Placeholder image

Aldie Counseling Center, situated in Langhorne, PA, delivers comprehensive substance abuse treatment for individuals of all ages. Their offerings include intensive outpatient services, standard outpatient care, and medication-assisted treatment utilizing methadone, buprenorphine, or naltrexone. The center emphasizes therapeutic modalities such as anger management, brief interventions, and cognitive behavioral therapy, ensuring personalized treatment plans. They further distinguish themselves with specialized programs designed for adult men, adult women, and survivors of sexual abuse, allowing for highly focused support. Aldie Counseling Center is committed to providing effective and empathetic addiction recovery services to both male and female clients.

Placeholder image
Reidsville, NC

ALEF Behavioral Group, located in Reidsville, NC, delivers tailored outpatient addiction recovery services for adults and young adults. Their offerings include intensive outpatient care, standard outpatient services, and medication-assisted treatment utilizing methadone, buprenorphine, or naltrexone. The center employs strategies such as 12-step facilitation, anger management, and brief intervention, all customized to meet individual client requirements. ALEF Behavioral Group extends specialized care to pregnant and postpartum women, and maintains distinct programs for male and female clients to foster a supportive, gender-sensitive recovery atmosphere. Opt for ALEF Behavioral Group for reliable and impactful substance use disorder treatment.

Placeholder image

ALEF Behavioral Group Reidsville, located in Reidsville, NC, specializes in providing tailored treatment for substance use disorders for both adults and young adults. The facility features intensive outpatient programs, standard outpatient services, and options for methadone/buprenorphine or naltrexone treatment. Emphasizing 12-step support, anger management, and brief intervention techniques, the center serves clients of all genders. Additionally, it offers specialized programs for pregnant and postpartum women, ensuring holistic support for every individual. Committed to high-quality care and personalized treatment plans, this center is an essential resource for effective addiction recovery in the Reidsville region.

Placeholder image
Birmingham, AL

Aletheia House, located in Birmingham, AL, provides comprehensive long-term residential care and around-the-clock support for individuals undergoing substance use rehabilitation. The center is dedicated to helping adult and senior women, including those who are pregnant or new mothers, with a focus on treatment strategies such as anger management, cognitive behavioral therapy, and motivational incentives. Aletheia House emphasizes holistic care, creating a nurturing and secure atmosphere conducive to healing. By offering personalized care plans and employing evidence-based methodologies, the center effectively addresses the unique challenges faced by each client. For women in need of thorough and empathetic addiction recovery services, Aletheia House is recognized for its exceptional commitment to fostering empowerment and sustainable recovery.

Placeholder image
Huntsville, AL

Aletheia House in Huntsville, AL, provides thorough addiction recovery services through its intensive outpatient, standard outpatient, and partial hospitalization programs. Employing proven therapeutic methods such as 12-step integration, cognitive behavioral therapy, and contingency management, this center supports adult men and women, with a particular focus on individuals affected by domestic abuse. Aletheia House delivers customized support for young adults and adults of all genders, emphasizing a personalized and high-quality approach to foster long-term sobriety.

Frequently Asked Questions

What is buprenorphine and how does it treat opioid addiction?
Buprenorphine is a partial opioid agonist medication approved by the FDA for treating opioid use disorder. It binds to the same receptors as heroin and fentanyl but produces a much weaker effect, reducing cravings and withdrawal symptoms without causing intense euphoria. Buprenorphine has a ceiling effect, meaning its opioid effects plateau at moderate doses, making it safer than methadone in terms of overdose risk.
What is the difference between Suboxone and Subutex?
Suboxone contains two active ingredients — buprenorphine and naloxone — while Subutex contains only buprenorphine without naloxone. The naloxone in Suboxone is included as an abuse deterrent; it remains inactive when taken sublingually as prescribed but triggers withdrawal if the medication is injected. Subutex is generally reserved for patients who cannot tolerate naloxone, such as pregnant women.
What is a Sublocade injection and how does it work?
Sublocade is a once-monthly injectable form of buprenorphine administered as a subcutaneous injection in the abdominal area. After injection, the medication forms a solid deposit under the skin that slowly releases buprenorphine over the course of a month. This eliminates daily dosing and removes the possibility of missed doses or medication diversion.
What are the common side effects of Suboxone?
Common Suboxone side effects include headache, nausea, constipation, insomnia, sweating, and mouth numbness or pain from sublingual administration. Some patients also experience dizziness, drowsiness, and blurred vision, particularly when starting treatment. Most side effects diminish within the first few weeks as the body adjusts. Patients should report difficulty breathing or signs of allergic reaction immediately.
What happens during Suboxone withdrawal?
Suboxone withdrawal occurs when a patient stops taking the medication abruptly after prolonged use, with symptoms including muscle aches, anxiety, insomnia, nausea, and irritability. A medically supervised taper is strongly recommended, typically reducing the dose by small increments over weeks or months. The risk of opioid relapse is significantly higher during unsupervised discontinuation.
How does Suboxone compare to methadone?
Suboxone and methadone are both effective for opioid use disorder but differ in key ways. Methadone is a full opioid agonist dispensed daily at licensed clinics, while Suboxone is a partial agonist that can be prescribed by qualified physicians and taken at home. Suboxone carries a lower overdose risk due to its ceiling effect and offers greater convenience, though methadone may be more appropriate for patients with severe, long-standing dependence.
How can I find a Suboxone clinic or doctor near me?
The most reliable way to find a Suboxone provider is through SAMHSA's online treatment locator at findtreatment.gov, which allows you to search by location and filter for buprenorphine providers. Many primary care offices, addiction treatment centers, and telehealth platforms now offer Suboxone prescriptions following the elimination of the federal X-waiver requirement in early 2023.
What is Zubsolv and how is it different from Suboxone?
Zubsolv is a brand-name buprenorphine and naloxone sublingual tablet that features a mint flavor and dissolves faster under the tongue than other options. Due to its higher bioavailability, Zubsolv uses different dosing strengths — a Zubsolv 5.7 mg/1.4 mg tablet is considered equivalent to a Suboxone 8 mg/2 mg dose. Patients switching between products should work closely with their prescriber for correct dose conversion.
Does Medicaid cover Suboxone treatment?
Yes — Medicaid covers buprenorphine (including Suboxone, Sublocade, Subutex, Zubsolv, and Brixadi) for opioid use disorder in all 50 states, as required by the SUPPORT Act of 2018. Medicaid is the largest single payer for MAT in the US. Coverage details vary by state — some require prior authorization or limit certain formulations. Many OBOT clinics accept Medicaid directly; telehealth Suboxone providers also bill Medicaid in most states. Bring your Medicaid card to your intake appointment.
Can I get Suboxone through telehealth?
Yes. After the MAT Act of 2023 permanently eliminated the X-waiver requirement, any licensed prescriber can prescribe Suboxone via telehealth in most states. The DEA also extended COVID-era telehealth flexibilities through at least 2025, allowing virtual Suboxone induction without a prior in-person visit. Several specialty platforms — Bicycle Health, Ophelia, Workit Health, Boulder Care — offer Medicaid-accepting telehealth Suboxone treatment. Telehealth has dramatically expanded access in rural and underserved areas with no nearby OBOT physicians.

About Buprenorphine (Suboxone)

Buprenorphine is classified as a partial opioid agonist, meaning it activates opioid receptors in the brain but to a much lesser degree than full agonists such as heroin, fentanyl, or oxycodone. This partial activation suppresses withdrawal symptoms and reduces cravings without producing dangerous respiratory depression or intense euphoria. Buprenorphine also has an unusually high binding affinity for the mu-opioid receptor, effectively blocking other opioids from attaching — providing a protective effect against relapse-related overdose.

How Buprenorphine Works

One of the defining features of buprenorphine is its ceiling effect — after a certain dose threshold, increasing the amount does not produce additional opioid effects. This dramatically reduces the risk of fatal overdose compared to methadone or illicit opioids. The ceiling effect, combined with its long duration of action (24 to 72 hours), makes buprenorphine one of the safest and most effective tools in medication-assisted treatment (MAT). Approved by the FDA in 2002, buprenorphine was a breakthrough because it could be prescribed in outpatient settings rather than requiring daily clinic visits.

Buprenorphine Brand Comparison: Suboxone, Subutex, Sublocade, Zubsolv, Brixadi

Buprenorphine is available under several FDA-approved brand names, each with distinct formulations, dosing schedules, and clinical use cases. The comparison below highlights the key differences:

BrandActive ingredientFormFrequencySettingFDA yearBest for
SuboxoneBuprenorphine + naloxoneSublingual film / tabletDailyOBOT, telehealth, retail pharmacy2002Most prescribed; naloxone deters injection misuse
SubutexBuprenorphine (alone)Sublingual tabletDailyOBOT2002Pregnancy; documented naloxone sensitivity
SublocadeBuprenorphine extended-releaseSubcutaneous injection (ATRIGEL depot)MonthlyClinic-administered2017No daily dosing; eliminates diversion risk
ZubsolvBuprenorphine + naloxoneSublingual tablet (higher bioavailability)DailyOBOT2013Faster dissolution; mint flavor; lower mg/dose
BrixadiBuprenorphine extended-releaseSubcutaneous injectionWeekly or monthlyClinic2023Newer alternative to Sublocade; weekly option for induction

All five medications are Schedule III controlled substances and equivalent in clinical efficacy at appropriate doses. The choice depends on adherence patterns, lifestyle, insurance coverage, and clinical context (e.g., pregnancy, prior injection use, daily-dosing burden). Many patients begin on sublingual Suboxone for stabilization and transition to monthly Sublocade or weekly Brixadi after sustained recovery.

Buprenorphine Side Effects

Common buprenorphine side effects include:

  • Headache and dizziness
  • Nausea and vomiting, especially during induction
  • Constipation and insomnia
  • Excessive sweating
  • Mouth numbness or oral discomfort from sublingual formulations

More serious side effects may include respiratory depression (particularly when combined with benzodiazepines or alcohol), liver problems, and allergic reactions. For most patients, side effects are mild and resolve within one to two weeks. The benefits in preventing relapse and overdose death significantly outweigh the risks.

Buprenorphine Dosage and Induction

Treatment begins with an induction phase where the patient must be in mild to moderate opioid withdrawal. Common induction doses range from 2 mg to 8 mg on the first day, with increases over the following days. Most patients stabilize on 8 mg to 24 mg per day, with 16 mg being the most commonly prescribed dose. Research suggests doses of 16 mg or higher are associated with better retention and outcomes. Dosage should always be adjusted under medical supervision.

Buprenorphine/Naloxone Combination

Many buprenorphine formulations include naloxone as an abuse deterrent. When taken sublingually as directed, naloxone has very low bioavailability and produces no clinical effect. However, if someone attempts to inject the medication, the naloxone component becomes fully active and triggers severe withdrawal. This design discourages injection misuse while having no impact on patients who take the medication correctly. The combination is the standard first-line formulation for opioid addiction treatment.

Suboxone: Sublingual Buprenorphine

Suboxone is the most recognized brand name for buprenorphine-naloxone and is most commonly dispensed as a sublingual film (Suboxone strips) that dissolves under the tongue. Suboxone has transformed opioid treatment by enabling millions of patients to receive effective pharmacotherapy in outpatient settings without the daily clinic visits required by methadone programs.

Suboxone Side Effects

Commonly reported Suboxone side effects include headache, nausea, tongue or mouth irritation, constipation, insomnia, sweating, and decreased libido. The sublingual film can cause irritation or small sores inside the mouth — rotating placement between under the tongue and against the cheek helps minimize this. Patients should not eat, drink, or smoke while the film is dissolving.

Suboxone Strips: Film vs. Tablet

Suboxone strips (sublingual film) have largely replaced the original tablet form. The film dissolves more quickly (two to four minutes), provides more consistent absorption, and is harder to divert due to individual foil packaging. Generic buprenorphine-naloxone tablets are often less expensive and may be preferred for cost reasons. Both are therapeutically equivalent when taken as prescribed.

Suboxone Treatment Programs

Comprehensive Suboxone treatment typically includes three phases:

  • Induction: Initial dosing under medical supervision, requiring the patient to be in early withdrawal
  • Stabilization: Dose adjustment until cravings and withdrawal are minimal, usually one to two months
  • Maintenance: Stable dosing for an extended period — often a year or longer — combined with counseling and behavioral therapy

Evidence consistently shows that longer treatment durations are associated with better outcomes. Most addiction medicine experts recommend a minimum of one to two years of maintenance therapy.

Find a Suboxone Clinic Near You — OBOT & Telehealth Options

Finding a Suboxone clinic has become significantly easier since the federal government eliminated the X-waiver requirement in January 2023, meaning any provider with a standard DEA license can now prescribe Suboxone. Patients can search SAMHSA's treatment locator at findtreatment.gov or use our directory to locate nearby facilities that offer buprenorphine-based treatment.

Suboxone Doctors Near Me

Beyond SAMHSA's locator, many state health departments maintain directories of addiction treatment providers. Telehealth has dramatically expanded access — several platforms now offer virtual Suboxone consultations, which is especially valuable for patients in rural areas. When selecting a provider, look for those offering comprehensive treatment including counseling, not just medication prescriptions.

Suboxone Withdrawal and Tapering

Suboxone withdrawal can include muscle aches, anxiety, insomnia, nausea, sweating, and intense opioid cravings. A gradual, medically supervised taper is recommended — typically reducing the dose by 10 to 25 percent every one to four weeks. Slower tapers over several months produce fewer symptoms and lower relapse rates. There is no medically mandated time limit for Suboxone treatment, and many patients benefit from indefinite maintenance.

Suboxone vs Methadone

Suboxone can be prescribed in office settings and taken at home, carries lower overdose risk due to its ceiling effect, and offers greater scheduling flexibility. Methadone is a full agonist that may be more effective for severe, long-standing dependence but must be dispensed at licensed clinics with daily visits. Neither is inherently superior — the best choice keeps the patient in treatment. Some patients may also benefit from naltrexone, a non-opioid alternative.

Sublocade: Monthly Buprenorphine Injection

Sublocade delivers buprenorphine as a once-monthly subcutaneous injection in the abdominal area using the ATRIGEL delivery system, which forms a solid biodegradable depot that slowly releases medication. Patients must first stabilize on sublingual buprenorphine (8 mg+ daily) for at least seven days. Treatment typically begins with two 300 mg injections, followed by maintenance on 300 mg or 100 mg. Sublocade eliminates concerns about daily adherence, missed doses, and medication diversion.

Sublocade Side Effects

The most common Sublocade side effects are injection-site reactions (pain, itching, redness, or a noticeable lump), nausea, constipation, headache, and fatigue. The injection-site lump is normal and gradually diminishes as medication is absorbed. Patients should avoid rubbing or massaging the site. Elevated liver enzymes may also occur but are usually mild and transient.

Subutex: Buprenorphine Without Naloxone

Subutex was the original brand-name buprenorphine product. While the brand has been discontinued, generic buprenorphine-only tablets remain available. Buprenorphine monotherapy is typically reserved for pregnant patients (to avoid naloxone exposure to the fetus), patients with documented naloxone sensitivity, or sometimes during the induction phase before transitioning to the combination product.

Subutex vs Suboxone

The primary difference is the absence of naloxone in Subutex. Because Subutex lacks the abuse-deterrent naloxone component, it may carry slightly higher diversion risk, and many insurance formularies prioritize the combination as the default. Current clinical guidelines favor buprenorphine-only formulations primarily for pregnancy and naloxone sensitivity.

Zubsolv: Alternative Buprenorphine Brand

Zubsolv is a buprenorphine-naloxone sublingual tablet featuring a mint flavor and faster dissolution (under two minutes). Due to enhanced bioavailability, Zubsolv uses different dose strengths — a 5.7 mg/1.4 mg tablet equals a Suboxone 8 mg/2 mg dose. Zubsolv is available in multiple strengths for flexible dosing during both induction and maintenance.

Buprenorphine resources:

Find Buprenorphine (Suboxone) by State

Browse buprenorphine (suboxone) programs in states with the most treatment options.

Explore Related Options

Related conditions, treatment approaches, and levels of care.

Medically Reviewed Updated May 2026

Reviewed by licensed addiction specialists. Information reflects current clinical guidance.

Sources:SAMHSA·NIDA·CDC

Need immediate help? Call SAMHSA: 1-800-662-4357 (24/7, free)