NWVCIL Logo
Medically Reviewed Content
Updated: August 2026
Sources: SAMHSA, NIDA

Suboxone Clinic Near You: Buprenorphine Treatment for Opioid Addiction

Find a Suboxone clinic near you. Buprenorphine — sold under brand names Suboxone, Sublocade, Subutex, Zubsolv, and Brixadi — is the most-prescribed MAT for opioid use disorder. It is a partial mu-opioid agonist with a ceiling effect that dramatically reduces overdose risk vs. methadone. After the MAT Act of 2023 eliminated the X-waiver requirement, any licensed prescriber can prescribe buprenorphine in office-based settings (OBOT), via telehealth, or at retail pharmacies. Buprenorphine is a Schedule III controlled substance and is covered by Medicaid in all 50 states.

Found 7,145 treatment centers offering buprenorphine (suboxone) across the United States.

Need Help Finding the Right Treatment Center?

Speak with a compassionate specialist now - 100% free & confidential

Call +1 (833) 244-3031
Available 24/7
All 50 States
Filters:

Showing 21 of 7145 results

Genesis Center of Winder LLC

Situated in Winder, GA, Genesis Center of Winder LLC provides an extensive array of outpatient rehabilitation options. The center emphasizes detoxification and treatment for substance use disorders, utilizing evidence-based methods like 12-step support, anger management techniques, and brief interventions. Tailored programs are designed specifically for active military members as well as adults, both men and women. Catering to a diverse group of adults and young adults, the facility offers customized care for each gender. With a commitment to high-quality care and individualized treatment strategies, Genesis Center of Winder LLC is focused on helping individuals navigate their path to recovery from addiction.

Gaudenzia DRC Inc
Philadelphia, PA

Situated in Philadelphia, PA, Gaudenzia DRC Inc specializes in a variety of services aimed at individuals in need of substance use rehabilitation and assistance with concurrent mental health issues. The center offers a range of treatment options including intensive outpatient programs, standard outpatient care, and outpatient services utilizing medications such as methadone, buprenorphine, or naltrexone. Gaudenzia DRC Inc employs techniques including 12-step support, anger management, and brief interventions, serving both adult men and women, as well as those affected by intimate partner violence. With a commitment to addressing the specific needs of adults and young adults, Gaudenzia DRC Inc stands out as a premier option for those seeking thorough and customized rehabilitation care.

Gaudenzia Inc

At Gaudenzia Inc in Erie, PA, we are dedicated to providing effective, research-backed therapeutic interventions for individuals struggling with substance use disorders and concurrent serious mental health challenges, as well as emotional difficulties in youth. Our offerings include intensive, regular, and standard outpatient care, drawing upon proven methods such as cognitive behavioral therapy, contingency management, and the Matrix Model. Gaudenzia Inc emphasizes personalized treatment plans for adults and young people of any gender, ensuring that each person receives high-quality, gender-affirming care specifically designed for their individual recovery path.

Gaudenzia Inc
Norristown, PA

Gaudenzia Inc, situated in Norristown, PA, delivers individualized substance abuse rehabilitation services. This establishment offers various levels of care including intensive outpatient, outpatient, and standard outpatient programs. Employing therapeutic strategies like 12-step facilitation, brief intervention, and cognitive behavioral therapy, the center supports adolescents and adults of both genders. Gaudenzia Inc is committed to providing tailored support for all clients, including children and adolescents, fostering a holistic path toward recovery.

Gaudenzia Inc

Situated in Erie, PA, Gaudenzia Inc provides exceptional rehabilitation services tailored for women and older adults. With an emphasis on treating substance abuse and co-occurring mental health issues, the facility offers extended residential programs that incorporate 12-step methodologies, brief interventions, and cognitive behavioral approaches. This center is distinguished by its targeted initiatives for adult women, those who have faced sexual trauma or abuse, and young adults dealing with significant emotional difficulties. Gaudenzia Inc fosters a nurturing and secure atmosphere for those in need of thorough and individualized support to tackle addiction and mental health obstacles.

Gaudenzia Inc
Bristol, PA

Gaudenzia Inc in Bristol, PA, serves those in need of extensive addiction recovery solutions through a variety of targeted services. The center features residential detox services alongside multiple residential treatment options designed for adults and young adults dealing with substance use issues and concurrent mental health conditions. Utilizing approaches such as 12-step programs, brief interventions, and cognitive behavioral therapy, the facility delivers research-backed treatment. Special programs are available for adult men and women, as well as for individuals who have suffered from intimate partner or domestic violence. Gaudenzia Inc in Bristol prioritizes high-quality care for all clients, fostering a nurturing atmosphere conducive to healing.

Gavin Foundation

The Gavin Foundation, situated in Boston, MA, specializes in a wide array of treatment services for substance use disorders, serving both adults and youth. This facility offers various levels of care, including intensive and standard outpatient programs, as well as medication-assisted treatment with methadone, buprenorphine, or naltrexone. Emphasizing 12-step support, anger management, and short intervention techniques, the center addresses the needs of those facing both addiction and significant mental health challenges. There are dedicated services for both men and women to provide customized support for each group. The Gavin Foundation is committed to delivering effective, gender-responsive treatment to aid individuals in their recovery journey.

Genesee Council On Alc/Subst Abuse

Genesee Council On Alc/Subst Abuse, located in Batavia, NY, delivers outpatient services for individuals facing substance use challenges. They provide specialized support for adults managing co-occurring serious mental health disorders. Their treatment approaches include anger management, cognitive behavioral therapy, and brief intervention strategies. The center is committed to personalized care, offering distinct programs for adolescents, adult men, and women. Their services extend to adults, children and adolescents, and seniors, with gender-specific options available. The facility also offers outpatient treatment using methadone, buprenorphine, or naltrexone, alongside general outpatient care, to support comprehensive recovery journeys.

Gaudenzia Crownsville
Crownsville, MD

Gaudenzia Crownsville, situated in Crownsville, Maryland, delivers a wide array of addiction recovery services. This center offers long-term residential treatment, detoxification programs, and round-the-clock support. Designed to meet the needs of various individuals, Gaudenzia Crownsville features tailored programs for active duty service members, as well as distinct tracks for adult males and females. Employing proven methods such as 12-step practices, anger management techniques, and brief intervention strategies, the facility promotes effective recovery pathways. It provides a nurturing and supportive setting for both adults and young adults aiming to conquer substance use challenges.

Gaudenzia Inc
Middleburg, PA

Situated in Middleburg, PA, Gaudenzia Inc provides extensive services for substance use recovery through its intensive outpatient, outpatient, and outpatient programs featuring methadone, buprenorphine, or naltrexone. The center employs evidence-based methods such as cognitive behavioral therapy, the Matrix Model, and motivational interviewing to address the needs of adults, adolescents, men, and women. Gaudenzia Inc offers specialized programs designed for different age groups and genders, ensuring individualized treatment for each patient. With a strong focus on high-quality care and a variety of treatment options, Gaudenzia Inc serves as an essential resource for individuals pursuing effective addiction recovery in the Middleburg community.

Gaudenzia Inc
Philadelphia, PA

Situated in Philadelphia, PA, Gaudenzia Inc specializes in extended residential care and transitional living arrangements for women facing challenges related to substance use disorders. This center features tailored programs for those who have undergone experiences of intimate partner violence, domestic violence, or sexual assault. Emphasizing a 12-step methodology along with anger management and short intervention strategies, Gaudenzia Inc is committed to providing personalized support for adult and senior women on their path to recovery within a nurturing setting. For anyone seeking effective addiction recovery solutions with a focus on women's needs, this center is devoted to guiding women towards sustained sobriety and holistic health.

Gaudenzia Inc

Gaudenzia Inc, situated in Erie, Pennsylvania, delivers extensive treatment options for adult men battling substance use issues within a nurturing and organized setting. The center offers various services, including long-term residential care, transitional housing, and halfway housing. Emphasizing methods such as 12-step programs, anger management, and brief intervention techniques, Gaudenzia Inc is dedicated to aiding individuals in their recovery path. Tailored specifically for adult males, this establishment serves adults, seniors, and young adults alike. With continuous support and an all-male environment, Gaudenzia Inc guarantees a secure and effective rehabilitation experience for those in need of assistance with addiction.

Placeholder image
Sharon, PA

Situated in Sharon, PA, Gaudenzia Inc delivers an all-encompassing treatment experience for adults facing substance use challenges alongside mental health disorders, as well as for children with significant emotional difficulties. The center provides a range of services, including intensive outpatient, outpatient, and day treatment options founded on proven methodologies such as cognitive behavioral therapy, contingency management, and the Matrix Model. Emphasizing personalized care, Gaudenzia Inc serves both men and women, ensuring that each client's needs are specifically addressed. Whether you are seeking assistance for yourself or for someone you care about, this facility's dedication to exceptional care and specialized treatment programs positions it as a leading option for those ready to begin their recovery journey.

Placeholder image
West Chester, PA

Situated in West Chester, PA, Gaudenzia Inc provides an extensive array of substance abuse treatment options for both adults and young adults facing dual diagnosis issues. This center offers various programs, including long-term, short-term, and around-the-clock residential care, designed to meet individual requirements. Gaudenzia Inc features specialized tracks for adult men, adult women, and individuals impacted by intimate partner violence, ensuring each client receives tailored support. Their treatment methodologies incorporate evidence-based practices such as 12-step facilitation, anger management strategies, and brief intervention methods. Dedicated to delivering high-quality care, this facility accommodates both male and female participants in pursuit of successful recovery solutions.

Placeholder image
Sunbury, PA

Situated in Sunbury, PA, Gaudenzia Inc delivers exceptional care for substance use disorders with diverse methodologies such as cognitive behavioral therapy, the Matrix Model, and motivational interviewing. The center features intensive outpatient care, standard outpatient services, as well as outpatient treatments utilizing methadone, buprenorphine, or naltrexone. Gaudenzia Inc also offers specialized programs designed for adolescents, adult men, and adult women, catering to various age brackets and gender identities, including children and teens. This facility is recognized for its all-encompassing and individualized approach to addiction recovery, making it an excellent choice for those seeking help for themselves or loved ones.

Placeholder image
Pottsville, PA

Gaudenzia Inc, situated in Pottsville, PA, delivers extensive treatment options for substance use disorders. The center features intensive outpatient programs, outpatient services, and treatments utilizing methadone/buprenorphine or naltrexone. It focuses on methods such as cognitive behavioral therapy, the Matrix Model, and motivational interviewing. Gaudenzia Inc offers specialized programs designed for adolescents, men, and women, catering to adults as well as children and teens of any gender. Patients can anticipate receiving high-quality care and assistance from a committed group of professionals, making this center a great option for those needing tailored and effective addiction recovery services.

Placeholder image
Lewisburg, PA

Gaudenzia Inc, situated in Lewisburg, PA, delivers thorough substance use rehabilitation for adult men and women. This center features intensive outpatient care, standard outpatient services, and medication-assisted treatment options including methadone, buprenorphine, or naltrexone. Employing proven therapeutic methods like cognitive behavioral therapy, the Matrix Model, and motivational interviewing, the facility is equipped to support individuals with a history of trauma. Gaudenzia Inc provides specialized programs for adults and young adults, with distinct options for male and female patients. Prioritizing high-quality, personalized recovery plans, this institution is committed to guiding individuals through addiction challenges toward sustained sobriety.

Placeholder image
Berwick, PA

Gaudenzia Inc, situated in Berwick, PA, provides comprehensive substance use disorder services, encompassing intensive outpatient, outpatient, and medication-assisted treatment options like methadone, buprenorphine, and naltrexone. The center employs evidence-based therapeutic modalities such as cognitive behavioral therapy, the Matrix Model, and motivational interviewing. Gaudenzia Inc is dedicated to serving a broad spectrum of individuals, with specialized programs designed for adolescents, adult men, and adult women. Their commitment to delivering high-quality care extends to both adults and young individuals, distinguished by personalized recovery strategies and robust support systems.

Placeholder image
Philadelphia, PA

Gaudenzia Inc, situated in Philadelphia, PA, is a prominent addiction treatment provider dedicated to assisting adults and young adults in their recovery from substance use disorders. They provide a range of services, including intensive outpatient care, standard outpatient programs, and medication-assisted treatment options such as methadone, buprenorphine, or naltrexone. Employing scientifically supported therapeutic strategies like 12-step facilitation, cognitive behavioral therapy, and contingency management, Gaudenzia Inc prioritizes a personalized approach to healing. The center welcomes both male and female individuals, ensuring that all clients receive thorough support designed for their unique circumstances. Gaudenzia Inc distinguishes itself through its unwavering dedication to superior treatment and bespoke recovery plans, establishing it as a premier destination for effective addiction recovery.

Placeholder image
Lancaster, PA

Gaudenzia Inc, located in Lancaster, PA, delivers extensive long-term and around-the-clock residential care for adults battling substance use disorders. The facility's robust program integrates techniques such as anger management, cognitive behavioral therapy, and motivational interviewing. Emphasizing the support of adult women, seniors, and young adults who have faced intimate partner violence, domestic abuse, or sexual assault, the center customizes its interventions to address individual challenges. Gaudenzia Inc in Lancaster is recognized for its empathetic approach and reliance on proven therapeutic strategies, positioning it as a premier option for individuals pursuing effective addiction recovery and assistance.

Placeholder image

Situated in Albion, NY, the Genesee/Orleans Council on Alc delivers exceptional addiction treatment services for adults and older individuals. This center provides an array of outpatient options, including treatments with methadone, buprenorphine, or naltrexone, as well as standard outpatient programs. Techniques employed here encompass anger management, brief interventions, and cognitive behavioral therapy. The facility offers dedicated programs for different demographics, including adolescents and specific groups for adult men and women, ensuring personalized support for everyone. With its commitment to high-quality care and comprehensive rehabilitation strategies, the center serves as a vital support system for those in need of effective recovery solutions.

Frequently Asked Questions

What is buprenorphine and how does it treat opioid addiction?
Buprenorphine is a partial opioid agonist medication approved by the FDA for treating opioid use disorder. It binds to the same receptors as heroin and fentanyl but produces a much weaker effect, reducing cravings and withdrawal symptoms without causing intense euphoria. Buprenorphine has a ceiling effect, meaning its opioid effects plateau at moderate doses, making it safer than methadone in terms of overdose risk.
What is the difference between Suboxone and Subutex?
Suboxone contains two active ingredients — buprenorphine and naloxone — while Subutex contains only buprenorphine without naloxone. The naloxone in Suboxone is included as an abuse deterrent; it remains inactive when taken sublingually as prescribed but triggers withdrawal if the medication is injected. Subutex is generally reserved for patients who cannot tolerate naloxone, such as pregnant women.
What is a Sublocade injection and how does it work?
Sublocade is a once-monthly injectable form of buprenorphine administered as a subcutaneous injection in the abdominal area. After injection, the medication forms a solid deposit under the skin that slowly releases buprenorphine over the course of a month. This eliminates daily dosing and removes the possibility of missed doses or medication diversion.
What are the common side effects of Suboxone?
Common Suboxone side effects include headache, nausea, constipation, insomnia, sweating, and mouth numbness or pain from sublingual administration. Some patients also experience dizziness, drowsiness, and blurred vision, particularly when starting treatment. Most side effects diminish within the first few weeks as the body adjusts. Patients should report difficulty breathing or signs of allergic reaction immediately.
What happens during Suboxone withdrawal?
Suboxone withdrawal occurs when a patient stops taking the medication abruptly after prolonged use, with symptoms including muscle aches, anxiety, insomnia, nausea, and irritability. A medically supervised taper is strongly recommended, typically reducing the dose by small increments over weeks or months. The risk of opioid relapse is significantly higher during unsupervised discontinuation.
How does Suboxone compare to methadone?
Suboxone and methadone are both effective for opioid use disorder but differ in key ways. Methadone is a full opioid agonist dispensed daily at licensed clinics, while Suboxone is a partial agonist that can be prescribed by qualified physicians and taken at home. Suboxone carries a lower overdose risk due to its ceiling effect and offers greater convenience, though methadone may be more appropriate for patients with severe, long-standing dependence.
How can I find a Suboxone clinic or doctor near me?
The most reliable way to find a Suboxone provider is through SAMHSA's online treatment locator at findtreatment.gov, which allows you to search by location and filter for buprenorphine providers. Many primary care offices, addiction treatment centers, and telehealth platforms now offer Suboxone prescriptions following the elimination of the federal X-waiver requirement in early 2023.
What is Zubsolv and how is it different from Suboxone?
Zubsolv is a brand-name buprenorphine and naloxone sublingual tablet that features a mint flavor and dissolves faster under the tongue than other options. Due to its higher bioavailability, Zubsolv uses different dosing strengths — a Zubsolv 5.7 mg/1.4 mg tablet is considered equivalent to a Suboxone 8 mg/2 mg dose. Patients switching between products should work closely with their prescriber for correct dose conversion.
Does Medicaid cover Suboxone treatment?
Yes — Medicaid covers buprenorphine (including Suboxone, Sublocade, Subutex, Zubsolv, and Brixadi) for opioid use disorder in all 50 states, as required by the SUPPORT Act of 2018. Medicaid is the largest single payer for MAT in the US. Coverage details vary by state — some require prior authorization or limit certain formulations. Many OBOT clinics accept Medicaid directly; telehealth Suboxone providers also bill Medicaid in most states. Bring your Medicaid card to your intake appointment.
Can I get Suboxone through telehealth?
Yes. After the MAT Act of 2023 permanently eliminated the X-waiver requirement, any licensed prescriber can prescribe Suboxone via telehealth in most states. The DEA also extended COVID-era telehealth flexibilities through at least 2025, allowing virtual Suboxone induction without a prior in-person visit. Several specialty platforms — Bicycle Health, Ophelia, Workit Health, Boulder Care — offer Medicaid-accepting telehealth Suboxone treatment. Telehealth has dramatically expanded access in rural and underserved areas with no nearby OBOT physicians.

About Buprenorphine (Suboxone)

Buprenorphine is classified as a partial opioid agonist, meaning it activates opioid receptors in the brain but to a much lesser degree than full agonists such as heroin, fentanyl, or oxycodone. This partial activation suppresses withdrawal symptoms and reduces cravings without producing dangerous respiratory depression or intense euphoria. Buprenorphine also has an unusually high binding affinity for the mu-opioid receptor, effectively blocking other opioids from attaching — providing a protective effect against relapse-related overdose.

How Buprenorphine Works

One of the defining features of buprenorphine is its ceiling effect — after a certain dose threshold, increasing the amount does not produce additional opioid effects. This dramatically reduces the risk of fatal overdose compared to methadone or illicit opioids. The ceiling effect, combined with its long duration of action (24 to 72 hours), makes buprenorphine one of the safest and most effective tools in medication-assisted treatment (MAT). Approved by the FDA in 2002, buprenorphine was a breakthrough because it could be prescribed in outpatient settings rather than requiring daily clinic visits.

Buprenorphine Brand Comparison: Suboxone, Subutex, Sublocade, Zubsolv, Brixadi

Buprenorphine is available under several FDA-approved brand names, each with distinct formulations, dosing schedules, and clinical use cases. The comparison below highlights the key differences:

BrandActive ingredientFormFrequencySettingFDA yearBest for
SuboxoneBuprenorphine + naloxoneSublingual film / tabletDailyOBOT, telehealth, retail pharmacy2002Most prescribed; naloxone deters injection misuse
SubutexBuprenorphine (alone)Sublingual tabletDailyOBOT2002Pregnancy; documented naloxone sensitivity
SublocadeBuprenorphine extended-releaseSubcutaneous injection (ATRIGEL depot)MonthlyClinic-administered2017No daily dosing; eliminates diversion risk
ZubsolvBuprenorphine + naloxoneSublingual tablet (higher bioavailability)DailyOBOT2013Faster dissolution; mint flavor; lower mg/dose
BrixadiBuprenorphine extended-releaseSubcutaneous injectionWeekly or monthlyClinic2023Newer alternative to Sublocade; weekly option for induction

All five medications are Schedule III controlled substances and equivalent in clinical efficacy at appropriate doses. The choice depends on adherence patterns, lifestyle, insurance coverage, and clinical context (e.g., pregnancy, prior injection use, daily-dosing burden). Many patients begin on sublingual Suboxone for stabilization and transition to monthly Sublocade or weekly Brixadi after sustained recovery.

Buprenorphine Side Effects

Common buprenorphine side effects include:

  • Headache and dizziness
  • Nausea and vomiting, especially during induction
  • Constipation and insomnia
  • Excessive sweating
  • Mouth numbness or oral discomfort from sublingual formulations

More serious side effects may include respiratory depression (particularly when combined with benzodiazepines or alcohol), liver problems, and allergic reactions. For most patients, side effects are mild and resolve within one to two weeks. The benefits in preventing relapse and overdose death significantly outweigh the risks.

Buprenorphine Dosage and Induction

Treatment begins with an induction phase where the patient must be in mild to moderate opioid withdrawal. Common induction doses range from 2 mg to 8 mg on the first day, with increases over the following days. Most patients stabilize on 8 mg to 24 mg per day, with 16 mg being the most commonly prescribed dose. Research suggests doses of 16 mg or higher are associated with better retention and outcomes. Dosage should always be adjusted under medical supervision.

Buprenorphine/Naloxone Combination

Many buprenorphine formulations include naloxone as an abuse deterrent. When taken sublingually as directed, naloxone has very low bioavailability and produces no clinical effect. However, if someone attempts to inject the medication, the naloxone component becomes fully active and triggers severe withdrawal. This design discourages injection misuse while having no impact on patients who take the medication correctly. The combination is the standard first-line formulation for opioid addiction treatment.

Suboxone: Sublingual Buprenorphine

Suboxone is the most recognized brand name for buprenorphine-naloxone and is most commonly dispensed as a sublingual film (Suboxone strips) that dissolves under the tongue. Suboxone has transformed opioid treatment by enabling millions of patients to receive effective pharmacotherapy in outpatient settings without the daily clinic visits required by methadone programs.

Suboxone Side Effects

Commonly reported Suboxone side effects include headache, nausea, tongue or mouth irritation, constipation, insomnia, sweating, and decreased libido. The sublingual film can cause irritation or small sores inside the mouth — rotating placement between under the tongue and against the cheek helps minimize this. Patients should not eat, drink, or smoke while the film is dissolving.

Suboxone Strips: Film vs. Tablet

Suboxone strips (sublingual film) have largely replaced the original tablet form. The film dissolves more quickly (two to four minutes), provides more consistent absorption, and is harder to divert due to individual foil packaging. Generic buprenorphine-naloxone tablets are often less expensive and may be preferred for cost reasons. Both are therapeutically equivalent when taken as prescribed.

Suboxone Treatment Programs

Comprehensive Suboxone treatment typically includes three phases:

  • Induction: Initial dosing under medical supervision, requiring the patient to be in early withdrawal
  • Stabilization: Dose adjustment until cravings and withdrawal are minimal, usually one to two months
  • Maintenance: Stable dosing for an extended period — often a year or longer — combined with counseling and behavioral therapy

Evidence consistently shows that longer treatment durations are associated with better outcomes. Most addiction medicine experts recommend a minimum of one to two years of maintenance therapy.

Find a Suboxone Clinic Near You — OBOT & Telehealth Options

Finding a Suboxone clinic has become significantly easier since the federal government eliminated the X-waiver requirement in January 2023, meaning any provider with a standard DEA license can now prescribe Suboxone. Patients can search SAMHSA's treatment locator at findtreatment.gov or use our directory to locate nearby facilities that offer buprenorphine-based treatment.

Suboxone Doctors Near Me

Beyond SAMHSA's locator, many state health departments maintain directories of addiction treatment providers. Telehealth has dramatically expanded access — several platforms now offer virtual Suboxone consultations, which is especially valuable for patients in rural areas. When selecting a provider, look for those offering comprehensive treatment including counseling, not just medication prescriptions.

Suboxone Withdrawal and Tapering

Suboxone withdrawal can include muscle aches, anxiety, insomnia, nausea, sweating, and intense opioid cravings. A gradual, medically supervised taper is recommended — typically reducing the dose by 10 to 25 percent every one to four weeks. Slower tapers over several months produce fewer symptoms and lower relapse rates. There is no medically mandated time limit for Suboxone treatment, and many patients benefit from indefinite maintenance.

Suboxone vs Methadone

Suboxone can be prescribed in office settings and taken at home, carries lower overdose risk due to its ceiling effect, and offers greater scheduling flexibility. Methadone is a full agonist that may be more effective for severe, long-standing dependence but must be dispensed at licensed clinics with daily visits. Neither is inherently superior — the best choice keeps the patient in treatment. Some patients may also benefit from naltrexone, a non-opioid alternative.

Sublocade: Monthly Buprenorphine Injection

Sublocade delivers buprenorphine as a once-monthly subcutaneous injection in the abdominal area using the ATRIGEL delivery system, which forms a solid biodegradable depot that slowly releases medication. Patients must first stabilize on sublingual buprenorphine (8 mg+ daily) for at least seven days. Treatment typically begins with two 300 mg injections, followed by maintenance on 300 mg or 100 mg. Sublocade eliminates concerns about daily adherence, missed doses, and medication diversion.

Sublocade Side Effects

The most common Sublocade side effects are injection-site reactions (pain, itching, redness, or a noticeable lump), nausea, constipation, headache, and fatigue. The injection-site lump is normal and gradually diminishes as medication is absorbed. Patients should avoid rubbing or massaging the site. Elevated liver enzymes may also occur but are usually mild and transient.

Subutex: Buprenorphine Without Naloxone

Subutex was the original brand-name buprenorphine product. While the brand has been discontinued, generic buprenorphine-only tablets remain available. Buprenorphine monotherapy is typically reserved for pregnant patients (to avoid naloxone exposure to the fetus), patients with documented naloxone sensitivity, or sometimes during the induction phase before transitioning to the combination product.

Subutex vs Suboxone

The primary difference is the absence of naloxone in Subutex. Because Subutex lacks the abuse-deterrent naloxone component, it may carry slightly higher diversion risk, and many insurance formularies prioritize the combination as the default. Current clinical guidelines favor buprenorphine-only formulations primarily for pregnancy and naloxone sensitivity.

Zubsolv: Alternative Buprenorphine Brand

Zubsolv is a buprenorphine-naloxone sublingual tablet featuring a mint flavor and faster dissolution (under two minutes). Due to enhanced bioavailability, Zubsolv uses different dose strengths — a 5.7 mg/1.4 mg tablet equals a Suboxone 8 mg/2 mg dose. Zubsolv is available in multiple strengths for flexible dosing during both induction and maintenance.

Buprenorphine resources:

Find Buprenorphine (Suboxone) by State

Browse buprenorphine (suboxone) programs in states with the most treatment options.

Explore Related Options

Related conditions, treatment approaches, and levels of care.

Medically Reviewed Updated August 2026

Reviewed by licensed addiction specialists. Information reflects current clinical guidance.

Sources:SAMHSA·NIDA·CDC

Need immediate help? Call SAMHSA: 1-800-662-4357 (24/7, free)