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Medically Reviewed Content
Updated: August 2026
Sources: SAMHSA, NIDA

Suboxone Clinic Near You: Buprenorphine Treatment for Opioid Addiction

Find a Suboxone clinic near you. Buprenorphine — sold under brand names Suboxone, Sublocade, Subutex, Zubsolv, and Brixadi — is the most-prescribed MAT for opioid use disorder. It is a partial mu-opioid agonist with a ceiling effect that dramatically reduces overdose risk vs. methadone. After the MAT Act of 2023 eliminated the X-waiver requirement, any licensed prescriber can prescribe buprenorphine in office-based settings (OBOT), via telehealth, or at retail pharmacies. Buprenorphine is a Schedule III controlled substance and is covered by Medicaid in all 50 states.

Found 7,145 treatment centers offering buprenorphine (suboxone) across the United States.

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Hefner Comprehensive Treatment Center

Hefner Comprehensive Treatment Center, located in Oklahoma City, OK, delivers outpatient services aimed at addressing substance use disorders in both adults and young adults. This facility features tailored programs for both adult males and females, including those who have faced intimate partner or domestic violence. The treatment methods employed encompass 12-step facilitation, anger management, and brief interventions. Additionally, Hefner Comprehensive Treatment Center provides outpatient options for methadone, buprenorphine, or naltrexone therapy, alongside standard outpatient services. Committed to personalized care and high-quality treatment, this center is focused on aiding clients throughout their recovery process.

Heights Treatment

Heights Treatment, based in Houston, TX, presents a wide array of substance abuse recovery programs tailored for both adults and young adults. This facility focuses on addressing co-occurring substance use issues alongside significant mental health conditions. It offers various treatment options, including intensive outpatient programs, outpatient services, and day treatment, all designed to meet the individual needs of clients. Heights Treatment employs methodologies such as 12-step facilitation, cognitive behavioral therapy, and brief interventions, ensuring that the care provided is rooted in evidence-based practices. Specialized programs are also available for active military personnel, as well as for adult men and women. With an emphasis on delivering high-quality care and customized treatment strategies, Heights Treatment is a reputable option for individuals pursuing recovery.

Helio Health Inc
Syracuse, NY

Helio Health Inc, located in Syracuse, NY, provides extensive outpatient programs designed for adults dealing with substance use issues, including those experiencing mental health challenges alongside addiction. The center emphasizes tailored care for both adults and young adults, utilizing proven methods like cognitive-behavioral therapy and contingency management in its treatment. Helio Health Inc is particularly noted for its outpatient options involving methadone, buprenorphine, or naltrexone, promoting a well-rounded recovery process. With a focus on personalized care and high-quality treatment strategies, this facility is a reliable option for anyone in need of effective and compassionate addiction recovery services.

Heights Treatment
Los Angeles, CA

Heights Treatment, situated in Los Angeles, CA, delivers a complete suite of recovery programs for individuals struggling with addiction and coinciding mental health conditions, catering to both younger and adult populations. They feature robust intensive outpatient, day treatment, and partial hospitalization options. Their therapeutic approach emphasizes anger management techniques, cognitive behavioral strategies, and motivational rewards, ensuring each client receives a customized recovery journey. Heights Treatment is dedicated to offering exceptional care and an individualized recovery experience for all genders. This center provides a nurturing setting for those pursuing tailored and successful treatment for substance dependence.

Helen Ross McNabb Center

The Helen Ross McNabb Center in Knoxville, TN, delivers tailored rehabilitation programs designed for diverse treatment requirements. This establishment features robust outpatient services, including intensive outpatient, day treatment, and partial hospitalization, serving adults, youth, and young adults grappling with addiction and concurrent mental health challenges. Employing strategies such as brief intervention, cognitive behavioral therapy, and motivational interviewing, the center personalizes its therapeutic interventions. Specialized tracks for adult men, adult women, and individuals with trauma histories underscore its dedication to holistic support. The center’s gender-specific treatment modalities for men and women exemplify its pledge to superior and equitable rehabilitation care.

Helen Ross McNabb Center

Situated in Knoxville, TN, the Helen Ross McNabb Center delivers a wide range of rehabilitation services targeting substance use issues and concurrent mental health challenges for both adults and children. The center features intensive outpatient and regular outpatient options that utilize evidence-supported methods like brief interventions, motivational interviewing, and relapse prevention strategies. With focused programs designed for adult males, adult females, and survivors of sexual abuse, this facility addresses a variety of requirements. By catering to all genders among adult and young adult populations, the Helen Ross McNabb Center is committed to providing personalized care and support, prioritizing effective treatment and comprehensive recovery.

Helen Ross McNabb Center

The Helen Ross McNabb Center, located in Athens, TN, specializes in rehabilitation for both adults and seniors struggling with substance abuse and accompanying mental health challenges. The center offers a range of treatment options, including intensive outpatient services, outpatient programs, and medication-assisted treatments such as methadone, buprenorphine, or naltrexone. Each program is personalized to address the unique needs of each client. The center employs research-supported methods such as cognitive behavioral therapy and motivational interviewing to foster recovery. Additionally, there are dedicated programs for adult men and women, as well as individuals who have faced sexual abuse. Committed to delivering high-quality care, this facility provides a nurturing atmosphere for clients on their path to recovery and personal development.

Helio Health Inc
Rochester, NY

Helio Health Inc, located in Rochester, NY, provides extensive detox programs within a nurturing setting. With a focus on residential detox and round-the-clock support, this center employs customized treatment strategies founded on proven methods, including 12-step programming, cognitive behavioral therapy, and contingency management. The facility features specialized programs for adult men and women, as well as those who have faced intimate partner or domestic violence. Helio Health Inc serves a diverse clientele, including adults, children, adolescents, and young adults of any gender, prioritizing personalized treatment plans to ensure exceptional care.

Helen Ross McNabb
Maryville, TN

Helen Ross McNabb, situated in Maryville, TN, is a respected addiction recovery facility. They provide distinct therapeutic plans for individuals dealing with substance abuse and concurrent mental health conditions. Services include comprehensive outpatient care, general outpatient support, and medication-assisted treatment options. Employing methods like cognitive behavioral therapy and motivational interviewing, this establishment serves adults and older adults, alongside specific offerings for teenagers, adult males, and adult females. Dedicated to personalized recovery journeys, Helen Ross McNabb guarantees effective treatment for all clients, irrespective of gender, pursuing sobriety.

Helen Vine Recovery Center

Nestled in San Rafael, California, the Helen Vine Recovery Center delivers a complete suite of support for individuals pursuing freedom from addiction. This establishment offers extended stay residency, detox services, and continuous round-the-clock residential assistance. Emphasizing 12-step principles, strategies for emotional regulation, and concise counseling methods, the center is equipped to assist adult men and women, including survivors of trauma. Focusing on adults and young adults, the center features distinct pathways for each gender. Dedicated to delivering exceptional care, the Helen Vine Recovery Center stands as a reliable destination for those desiring a nurturing space in their pursuit of lasting recovery.

Helen Ross McNabb Center

Situated in Morristown, TN, the Helen Ross McNabb Center provides exceptional care for individuals grappling with substance use issues alongside significant mental health challenges. Their offerings encompass intensive outpatient programs, outpatient care, and medication-assisted treatment alternatives such as methadone and buprenorphine. Emphasizing brief interventions, cognitive behavioral therapy, and motivational interviewing, this center serves a diverse clientele, including adults, children, and the elderly, featuring particular programs aimed at adolescents, adult men, and women. With a commitment to personalized treatment for both genders, this facility is dedicated to delivering effective support for individuals on their recovery journey.

Helen Ross McNabb Center

Situated in Knoxville, TN, the Helen Ross McNabb Center delivers a wide range of rehabilitation services aimed at adults and young adults facing challenges with substance abuse alongside mental health disorders. The facility provides options for residential detox and short-term residential care, employing proven methods like cognitive behavioral therapy and motivational interviewing. Emphasizing personalized treatment, the center features tailored programs for adult men, adult women, and individuals who have endured sexual abuse. The dedicated staff supports both male and female clients, fostering an encouraging and inclusive atmosphere conducive to healing.

Helen Ross McNabb Center

Nestled in Oak Ridge, TN, the Helen Ross McNabb Center provides extensive substance use recovery options for individuals of all ages dealing with co-occurring severe mental health conditions. Their offerings encompass intensive outpatient services, standard outpatient programs, and targeted outpatient care involving methadone, buprenorphine, or naltrexone. Employing proven methods like cognitive behavioral therapy and motivational interviewing, this institution delivers personalized support for adult men, women, and trauma survivors. Catering to adults and seniors of all genders, the center is dedicated to delivering excellent treatment and assistance within a supportive setting for those pursuing successful recovery.

Hegira Health Inc

Hegira Health Inc, located in Livonia, MI, specializes in a wide range of substance abuse treatments for both adults and children dealing with concurrent mental health issues. The center provides intensive outpatient and outpatient programs, including services for methadone and buprenorphine. Utilizing proven techniques such as cognitive behavioral therapy and the Matrix Model, Hegira Health Inc addresses the unique needs of clients, including those with traumatic experiences, co-occurring conditions, and those affected by the criminal justice system. The center accommodates both male and female patients, ensuring that care is personalized for each individual. Committed to delivering quality and empathetic treatment, Hegira Health Inc plays an essential role in helping individuals navigate their recovery journey.

Hegira Health Inc

Hegira Health Inc, located in Taylor, MI, provides a wide range of substance use recovery services for both adults and children facing significant mental health challenges or emotional issues. The center offers both intensive outpatient and outpatient options, including treatments with methadone and buprenorphine. By implementing techniques such as brief interventions, cognitive behavioral therapy, and the Matrix Model, the center addresses the needs of those impacted by intimate partner violence, sexual trauma, or other adverse experiences. Hegira Health Inc serves both men and women, ensuring that care is tailored to meet the unique needs of each gender. Committed to delivering high-quality care and personalized treatment plans, this facility is focused on assisting individuals as they work towards recovery.

Helen Ross McNabb Center

The Helen Ross McNabb Center in Chattanooga, TN, provides extensive support for individuals grappling with addiction and dual diagnoses. They specialize in treating co-occurring substance use disorders and severe mental health challenges in adults, alongside emotional difficulties experienced by children. Their offerings include intensive and standard outpatient services, featuring medication-assisted treatment with methadone and buprenorphine. Employing scientifically validated methods such as cognitive behavioral therapy and motivational interviewing, the center designs distinct programs for adult men, women, and those who have experienced sexual trauma, ensuring personalized recovery journeys. Catering to adults and young adults of all genders, this institution delivers high-caliber recovery assistance aimed at fostering sustained well-being and comprehensive health.

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Westland, MI

Hegira Health Inc, located in Westland, MI, provides a wide range of substance abuse treatments for both adults and young individuals dealing with co-existing mental health issues. Their intensive outpatient and outpatient services feature a variety of treatment options, including methadone/buprenorphine and naltrexone therapies, designed to meet different client needs. The center employs evidence-based methods such as cognitive behavioral therapy and the Matrix Model to deliver tailored support, particularly for those involved in the criminal justice system and clients with dual diagnoses. With dedicated programs for both male and female participants, Hegira Health Inc emphasizes personalized, high-quality care aimed at fostering sustained recovery and overall wellness.

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Lincoln Park, MI

Hegira Health Inc, situated in Lincoln Park, MI, provides extensive outpatient care for individuals struggling with substance abuse and co-occurring mental health challenges, as well as emotional issues in young people. They offer targeted support for those who have experienced intimate partner violence, domestic abuse, sexual assault, and trauma. Employing proven therapeutic methods like brief intervention, cognitive behavioral therapy, and the Matrix Model, Hegira Health Inc serves clients of all genders and age groups. Their commitment to high-quality, personalized treatment plans guides individuals toward lasting recovery.

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Westland, MI

Hegira Health Inc in Westland, MI, provides extensive care for individuals struggling with substance use disorders. They offer several outpatient treatment avenues, such as medication-assisted treatment with methadone, buprenorphine, or naltrexone, standard outpatient services, and short-term intervention counseling. Specializing in motivational interviewing and strategies for preventing relapse, Hegira Health Inc delivers personalized support to adults and older adults, accommodating all genders. Their commitment to a client-centered methodology ensures that the services rendered are of the highest standard, fostering lasting recovery. This center is dedicated to creating a nurturing atmosphere for those on their journey to wellness and personal development.

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Westland, MI

Hegira Health Inc, located in Westland, MI, delivers specialized outpatient substance use disorder services, with a particular focus on individuals facing co-occurring mental health conditions. Their program encompasses medication-assisted treatment options like methadone, buprenorphine, and naltrexone, alongside general outpatient services. Employing strategies such as motivational interviewing, cognitive behavioral therapy, and the Matrix Model, they create personalized recovery plans. Hegira Health Inc also features distinct programs designed for active duty military personnel, adult men, and adult women, ensuring targeted support. Catering to adults and young adults of all genders, the center is committed to providing effective, scientifically-backed treatment within a supportive atmosphere.

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The Helen Ross McNabb Center in Sevierville, TN, delivers thorough addiction treatment for youth and adults facing significant mental health challenges. Through intensive and standard outpatient programs, it offers tailored support for those with dual diagnoses. The center employs strategies like brief intervention, cognitive behavioral therapy, and motivational interviewing, serving adult men and women, including survivors of sexual trauma. Catering to adults and older adults of all genders, the Helen Ross McNabb Center is dedicated to providing superior, personalized care to aid individuals in their recovery journey.

Frequently Asked Questions

What is buprenorphine and how does it treat opioid addiction?
Buprenorphine is a partial opioid agonist medication approved by the FDA for treating opioid use disorder. It binds to the same receptors as heroin and fentanyl but produces a much weaker effect, reducing cravings and withdrawal symptoms without causing intense euphoria. Buprenorphine has a ceiling effect, meaning its opioid effects plateau at moderate doses, making it safer than methadone in terms of overdose risk.
What is the difference between Suboxone and Subutex?
Suboxone contains two active ingredients — buprenorphine and naloxone — while Subutex contains only buprenorphine without naloxone. The naloxone in Suboxone is included as an abuse deterrent; it remains inactive when taken sublingually as prescribed but triggers withdrawal if the medication is injected. Subutex is generally reserved for patients who cannot tolerate naloxone, such as pregnant women.
What is a Sublocade injection and how does it work?
Sublocade is a once-monthly injectable form of buprenorphine administered as a subcutaneous injection in the abdominal area. After injection, the medication forms a solid deposit under the skin that slowly releases buprenorphine over the course of a month. This eliminates daily dosing and removes the possibility of missed doses or medication diversion.
What are the common side effects of Suboxone?
Common Suboxone side effects include headache, nausea, constipation, insomnia, sweating, and mouth numbness or pain from sublingual administration. Some patients also experience dizziness, drowsiness, and blurred vision, particularly when starting treatment. Most side effects diminish within the first few weeks as the body adjusts. Patients should report difficulty breathing or signs of allergic reaction immediately.
What happens during Suboxone withdrawal?
Suboxone withdrawal occurs when a patient stops taking the medication abruptly after prolonged use, with symptoms including muscle aches, anxiety, insomnia, nausea, and irritability. A medically supervised taper is strongly recommended, typically reducing the dose by small increments over weeks or months. The risk of opioid relapse is significantly higher during unsupervised discontinuation.
How does Suboxone compare to methadone?
Suboxone and methadone are both effective for opioid use disorder but differ in key ways. Methadone is a full opioid agonist dispensed daily at licensed clinics, while Suboxone is a partial agonist that can be prescribed by qualified physicians and taken at home. Suboxone carries a lower overdose risk due to its ceiling effect and offers greater convenience, though methadone may be more appropriate for patients with severe, long-standing dependence.
How can I find a Suboxone clinic or doctor near me?
The most reliable way to find a Suboxone provider is through SAMHSA's online treatment locator at findtreatment.gov, which allows you to search by location and filter for buprenorphine providers. Many primary care offices, addiction treatment centers, and telehealth platforms now offer Suboxone prescriptions following the elimination of the federal X-waiver requirement in early 2023.
What is Zubsolv and how is it different from Suboxone?
Zubsolv is a brand-name buprenorphine and naloxone sublingual tablet that features a mint flavor and dissolves faster under the tongue than other options. Due to its higher bioavailability, Zubsolv uses different dosing strengths — a Zubsolv 5.7 mg/1.4 mg tablet is considered equivalent to a Suboxone 8 mg/2 mg dose. Patients switching between products should work closely with their prescriber for correct dose conversion.
Does Medicaid cover Suboxone treatment?
Yes — Medicaid covers buprenorphine (including Suboxone, Sublocade, Subutex, Zubsolv, and Brixadi) for opioid use disorder in all 50 states, as required by the SUPPORT Act of 2018. Medicaid is the largest single payer for MAT in the US. Coverage details vary by state — some require prior authorization or limit certain formulations. Many OBOT clinics accept Medicaid directly; telehealth Suboxone providers also bill Medicaid in most states. Bring your Medicaid card to your intake appointment.
Can I get Suboxone through telehealth?
Yes. After the MAT Act of 2023 permanently eliminated the X-waiver requirement, any licensed prescriber can prescribe Suboxone via telehealth in most states. The DEA also extended COVID-era telehealth flexibilities through at least 2025, allowing virtual Suboxone induction without a prior in-person visit. Several specialty platforms — Bicycle Health, Ophelia, Workit Health, Boulder Care — offer Medicaid-accepting telehealth Suboxone treatment. Telehealth has dramatically expanded access in rural and underserved areas with no nearby OBOT physicians.

About Buprenorphine (Suboxone)

Buprenorphine is classified as a partial opioid agonist, meaning it activates opioid receptors in the brain but to a much lesser degree than full agonists such as heroin, fentanyl, or oxycodone. This partial activation suppresses withdrawal symptoms and reduces cravings without producing dangerous respiratory depression or intense euphoria. Buprenorphine also has an unusually high binding affinity for the mu-opioid receptor, effectively blocking other opioids from attaching — providing a protective effect against relapse-related overdose.

How Buprenorphine Works

One of the defining features of buprenorphine is its ceiling effect — after a certain dose threshold, increasing the amount does not produce additional opioid effects. This dramatically reduces the risk of fatal overdose compared to methadone or illicit opioids. The ceiling effect, combined with its long duration of action (24 to 72 hours), makes buprenorphine one of the safest and most effective tools in medication-assisted treatment (MAT). Approved by the FDA in 2002, buprenorphine was a breakthrough because it could be prescribed in outpatient settings rather than requiring daily clinic visits.

Buprenorphine Brand Comparison: Suboxone, Subutex, Sublocade, Zubsolv, Brixadi

Buprenorphine is available under several FDA-approved brand names, each with distinct formulations, dosing schedules, and clinical use cases. The comparison below highlights the key differences:

BrandActive ingredientFormFrequencySettingFDA yearBest for
SuboxoneBuprenorphine + naloxoneSublingual film / tabletDailyOBOT, telehealth, retail pharmacy2002Most prescribed; naloxone deters injection misuse
SubutexBuprenorphine (alone)Sublingual tabletDailyOBOT2002Pregnancy; documented naloxone sensitivity
SublocadeBuprenorphine extended-releaseSubcutaneous injection (ATRIGEL depot)MonthlyClinic-administered2017No daily dosing; eliminates diversion risk
ZubsolvBuprenorphine + naloxoneSublingual tablet (higher bioavailability)DailyOBOT2013Faster dissolution; mint flavor; lower mg/dose
BrixadiBuprenorphine extended-releaseSubcutaneous injectionWeekly or monthlyClinic2023Newer alternative to Sublocade; weekly option for induction

All five medications are Schedule III controlled substances and equivalent in clinical efficacy at appropriate doses. The choice depends on adherence patterns, lifestyle, insurance coverage, and clinical context (e.g., pregnancy, prior injection use, daily-dosing burden). Many patients begin on sublingual Suboxone for stabilization and transition to monthly Sublocade or weekly Brixadi after sustained recovery.

Buprenorphine Side Effects

Common buprenorphine side effects include:

  • Headache and dizziness
  • Nausea and vomiting, especially during induction
  • Constipation and insomnia
  • Excessive sweating
  • Mouth numbness or oral discomfort from sublingual formulations

More serious side effects may include respiratory depression (particularly when combined with benzodiazepines or alcohol), liver problems, and allergic reactions. For most patients, side effects are mild and resolve within one to two weeks. The benefits in preventing relapse and overdose death significantly outweigh the risks.

Buprenorphine Dosage and Induction

Treatment begins with an induction phase where the patient must be in mild to moderate opioid withdrawal. Common induction doses range from 2 mg to 8 mg on the first day, with increases over the following days. Most patients stabilize on 8 mg to 24 mg per day, with 16 mg being the most commonly prescribed dose. Research suggests doses of 16 mg or higher are associated with better retention and outcomes. Dosage should always be adjusted under medical supervision.

Buprenorphine/Naloxone Combination

Many buprenorphine formulations include naloxone as an abuse deterrent. When taken sublingually as directed, naloxone has very low bioavailability and produces no clinical effect. However, if someone attempts to inject the medication, the naloxone component becomes fully active and triggers severe withdrawal. This design discourages injection misuse while having no impact on patients who take the medication correctly. The combination is the standard first-line formulation for opioid addiction treatment.

Suboxone: Sublingual Buprenorphine

Suboxone is the most recognized brand name for buprenorphine-naloxone and is most commonly dispensed as a sublingual film (Suboxone strips) that dissolves under the tongue. Suboxone has transformed opioid treatment by enabling millions of patients to receive effective pharmacotherapy in outpatient settings without the daily clinic visits required by methadone programs.

Suboxone Side Effects

Commonly reported Suboxone side effects include headache, nausea, tongue or mouth irritation, constipation, insomnia, sweating, and decreased libido. The sublingual film can cause irritation or small sores inside the mouth — rotating placement between under the tongue and against the cheek helps minimize this. Patients should not eat, drink, or smoke while the film is dissolving.

Suboxone Strips: Film vs. Tablet

Suboxone strips (sublingual film) have largely replaced the original tablet form. The film dissolves more quickly (two to four minutes), provides more consistent absorption, and is harder to divert due to individual foil packaging. Generic buprenorphine-naloxone tablets are often less expensive and may be preferred for cost reasons. Both are therapeutically equivalent when taken as prescribed.

Suboxone Treatment Programs

Comprehensive Suboxone treatment typically includes three phases:

  • Induction: Initial dosing under medical supervision, requiring the patient to be in early withdrawal
  • Stabilization: Dose adjustment until cravings and withdrawal are minimal, usually one to two months
  • Maintenance: Stable dosing for an extended period — often a year or longer — combined with counseling and behavioral therapy

Evidence consistently shows that longer treatment durations are associated with better outcomes. Most addiction medicine experts recommend a minimum of one to two years of maintenance therapy.

Find a Suboxone Clinic Near You — OBOT & Telehealth Options

Finding a Suboxone clinic has become significantly easier since the federal government eliminated the X-waiver requirement in January 2023, meaning any provider with a standard DEA license can now prescribe Suboxone. Patients can search SAMHSA's treatment locator at findtreatment.gov or use our directory to locate nearby facilities that offer buprenorphine-based treatment.

Suboxone Doctors Near Me

Beyond SAMHSA's locator, many state health departments maintain directories of addiction treatment providers. Telehealth has dramatically expanded access — several platforms now offer virtual Suboxone consultations, which is especially valuable for patients in rural areas. When selecting a provider, look for those offering comprehensive treatment including counseling, not just medication prescriptions.

Suboxone Withdrawal and Tapering

Suboxone withdrawal can include muscle aches, anxiety, insomnia, nausea, sweating, and intense opioid cravings. A gradual, medically supervised taper is recommended — typically reducing the dose by 10 to 25 percent every one to four weeks. Slower tapers over several months produce fewer symptoms and lower relapse rates. There is no medically mandated time limit for Suboxone treatment, and many patients benefit from indefinite maintenance.

Suboxone vs Methadone

Suboxone can be prescribed in office settings and taken at home, carries lower overdose risk due to its ceiling effect, and offers greater scheduling flexibility. Methadone is a full agonist that may be more effective for severe, long-standing dependence but must be dispensed at licensed clinics with daily visits. Neither is inherently superior — the best choice keeps the patient in treatment. Some patients may also benefit from naltrexone, a non-opioid alternative.

Sublocade: Monthly Buprenorphine Injection

Sublocade delivers buprenorphine as a once-monthly subcutaneous injection in the abdominal area using the ATRIGEL delivery system, which forms a solid biodegradable depot that slowly releases medication. Patients must first stabilize on sublingual buprenorphine (8 mg+ daily) for at least seven days. Treatment typically begins with two 300 mg injections, followed by maintenance on 300 mg or 100 mg. Sublocade eliminates concerns about daily adherence, missed doses, and medication diversion.

Sublocade Side Effects

The most common Sublocade side effects are injection-site reactions (pain, itching, redness, or a noticeable lump), nausea, constipation, headache, and fatigue. The injection-site lump is normal and gradually diminishes as medication is absorbed. Patients should avoid rubbing or massaging the site. Elevated liver enzymes may also occur but are usually mild and transient.

Subutex: Buprenorphine Without Naloxone

Subutex was the original brand-name buprenorphine product. While the brand has been discontinued, generic buprenorphine-only tablets remain available. Buprenorphine monotherapy is typically reserved for pregnant patients (to avoid naloxone exposure to the fetus), patients with documented naloxone sensitivity, or sometimes during the induction phase before transitioning to the combination product.

Subutex vs Suboxone

The primary difference is the absence of naloxone in Subutex. Because Subutex lacks the abuse-deterrent naloxone component, it may carry slightly higher diversion risk, and many insurance formularies prioritize the combination as the default. Current clinical guidelines favor buprenorphine-only formulations primarily for pregnancy and naloxone sensitivity.

Zubsolv: Alternative Buprenorphine Brand

Zubsolv is a buprenorphine-naloxone sublingual tablet featuring a mint flavor and faster dissolution (under two minutes). Due to enhanced bioavailability, Zubsolv uses different dose strengths — a 5.7 mg/1.4 mg tablet equals a Suboxone 8 mg/2 mg dose. Zubsolv is available in multiple strengths for flexible dosing during both induction and maintenance.

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Medically Reviewed Updated August 2026

Reviewed by licensed addiction specialists. Information reflects current clinical guidance.

Sources:SAMHSA·NIDA·CDC

Need immediate help? Call SAMHSA: 1-800-662-4357 (24/7, free)