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Medically Reviewed Content
Updated: August 2026
Sources: SAMHSA, NIDA

Suboxone Clinic Near You: Buprenorphine Treatment for Opioid Addiction

Find a Suboxone clinic near you. Buprenorphine — sold under brand names Suboxone, Sublocade, Subutex, Zubsolv, and Brixadi — is the most-prescribed MAT for opioid use disorder. It is a partial mu-opioid agonist with a ceiling effect that dramatically reduces overdose risk vs. methadone. After the MAT Act of 2023 eliminated the X-waiver requirement, any licensed prescriber can prescribe buprenorphine in office-based settings (OBOT), via telehealth, or at retail pharmacies. Buprenorphine is a Schedule III controlled substance and is covered by Medicaid in all 50 states.

Found 7,145 treatment centers offering buprenorphine (suboxone) across the United States.

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HopeHealth Inc
Florence, SC

HopeHealth Inc, located in Florence, SC, provides a wide range of substance use rehabilitation services through different outpatient methods, including methadone and buprenorphine therapy, along with cognitive behavioral therapy. The center is dedicated to tackling issues like anger management and implementing brief interventions, serving both adult males and females, as well as individuals who have faced intimate partner violence. Additionally, HopeHealth Inc places an emphasis on adolescents, offering personalized treatment strategies for all clients. With its focus on evidence-driven practices and specialized offerings, the center guarantees top-notch assistance for individuals on their path to overcoming substance use challenges.

Hopes Horizon
Nottingham, MD

Situated in Nottingham, MD, Hopes Horizon delivers an extensive selection of addiction recovery services. The facility offers detox and a variety of substance use treatment options, including intensive outpatient, long-term residential, and standard outpatient programs. Emphasizing methods such as 12-step facilitation, brief intervention, and cognitive behavioral therapy, the center customizes treatment plans to address the unique needs of each individual. Hopes Horizon also features specialized programs catering to adult men, adult women, as well as those dealing with co-occurring mental health and substance use challenges. This center serves both adults and young adults, fostering a nurturing and healing environment for individuals of all genders.

HopeWorks
Albuquerque, NM

HopeWorks, situated in Albuquerque, NM, delivers extensive substance abuse recovery services for both adults and young adults facing serious mental health challenges or emotional issues. The center features long-term residential options, outpatient care, and treatments involving methadone/buprenorphine or naltrexone. HopeWorks emphasizes personalized support for those on their recovery journey. By employing methods such as 12-step facilitation, anger management, and brief interventions, this facility serves adult men and women, including those who have undergone trauma. The center is dedicated to providing specialized programs tailored to various age groups and genders, ensuring high-quality, individualized care for each person seeking assistance with addiction.

Horizon Health and Wellness

Horizon Health and Wellness, located in Globe, AZ, specializes in treating substance use disorders while also tackling serious co-occurring mental health conditions in adults and emotional challenges in children. The center provides both intensive outpatient and outpatient services, incorporating methadone and buprenorphine therapies. It emphasizes the 12-step approach, anger management techniques, and brief interventions. Featuring a distinct personalized method, the services are designed for adults and seniors, regardless of gender. Horizon Health and Wellness is dedicated to delivering high-quality, customized care, making it an excellent option for individuals in need of thorough and individualized rehabilitation support.

Horizon Health and Wellness

Horizon Health and Wellness, situated in Yuma, AZ, specializes in extensive treatment for substance use and co-occurring disorders for both adults and children. Emphasizing personalized care, the center offers a range of services including intensive outpatient programs, regular outpatient treatment, and day programs. By incorporating methods such as 12-step support, anger management strategies, and brief interventions, the facility customizes treatment plans to suit the distinct requirements of each individual. Catering to adults and seniors of all genders, Horizon Health and Wellness creates a nurturing atmosphere for those aiming to tackle addiction and mental health issues. Discover exceptional care and customized treatment at this premier rehabilitation center.

Horizon Health and Wellness

Horizon Health and Wellness, located in Casa Grande, AZ, provides targeted substance use rehabilitation for adults who are also dealing with significant mental health challenges. The center features both residential and short-term residential treatment options, delivering extensive care that includes 12-step support, anger management, and focused intervention strategies. It offers specialized programs designed specifically for adult men to provide customized assistance throughout their recovery process. Catering to both men and women, as well as young adults, Horizon Health and Wellness is dedicated to offering a comprehensive and personalized recovery experience. Emphasizing top-notch care and reliance on evidence-based methodologies, this facility serves as a guiding light for individuals striving to overcome addiction and related mental health struggles.

Horizon Health and Wellness

Horizon Health and Wellness, located in Casa Grande, AZ, provides a wide array of treatment services for individuals dealing with substance use challenges, specifically designed for both adults and young adults. The center has a particular focus on addressing co-occurring disorders in adults, as well as serious emotional issues in children. Treatment options available at this facility include intensive outpatient programs and outpatient services, along with medication-assisted therapies such as methadone, buprenorphine, and naltrexone. Horizon Health and Wellness emphasizes personalized care, utilizing various therapeutic methods, including anger management, brief interventions, and cognitive behavioral therapy. Furthermore, the center features specialized programs for those who have faced trauma. Committed to delivering high-quality care, the facility accommodates both men and women in pursuit of effective rehabilitation options.

Horizon Health and Wellness

Horizon Health and Wellness, situated in Florence, AZ, specializes in treating substance use and co-occurring disorders for adults facing significant mental health challenges, as well as children dealing with severe emotional issues. The center offers a range of treatment opportunities, including intensive outpatient programs, regular outpatient services, and options for methadone, buprenorphine, or naltrexone. Emphasizing anger management, cognitive behavioral therapy, and the Matrix Model, the facility customizes its programs to meet each individual's needs. Horizon Health and Wellness serves adults and seniors across all genders, fostering a nurturing atmosphere conducive to recovery. Discover individualized care and research-backed methods at this esteemed rehabilitation facility.

Horizon Health and Wellness

Horizon Health and Wellness in Casa Grande, AZ, is dedicated to providing effective substance use disorder therapy within a compassionate setting. They offer both residential and extended care options designed for adults and adolescents, catering to diverse gender identities. Their distinctive therapeutic framework incorporates 12-step support, strategies for managing anger, and brief counseling techniques. Horizon Health and Wellness is committed to delivering high-caliber support, assisting individuals in their path to sustained wellness through customized recovery strategies. For those seeking a treatment center that respects and adapts to each person's unique road to abstinence, this center could be an excellent fit.

Horizon Health Services Inc

Horizon Health Services Inc, located in Buffalo, NY, delivers extensive outpatient care for individuals struggling with substance abuse and concurrent mental health issues, serving both adults and children. The facility features tailored programs for various demographics, including active military personnel, teenagers, and adult males, accommodating a range of ages and gender identities. Their treatment methods incorporate 12-step guidance, anger management strategies, and brief therapeutic interventions, all designed to ensure individualized support for each patient. Offering outpatient services along with methadone, buprenorphine, and naltrexone treatment options, the center is dedicated to providing high-quality care and assistance for those on their road to recovery. Horizon Health Services Inc stands as a reputable provider of effective and empathetic addiction treatment solutions.

Horizon Health Services Inc

Horizon Health Services Inc, located in Buffalo, NY, offers extensive outpatient care for individuals of all ages struggling with addiction and co-occurring mental health issues. The center features tailored programs for active military personnel, young people, and adult men, addressing a wide range of requirements. By employing methods like 12-step support, emotional regulation techniques, and short-term counseling, the facility guarantees personalized support. Horizon Health Services Inc delivers services such as outpatient medication-assisted treatment (MAT) with methadone, buprenorphine, or naltrexone, alongside general outpatient services, emphasizing effective and high-quality treatment for everyone. This organization stands as a symbol of optimism for those embarking on a journey of recovery and wellness.

Horizon Village Inc

Horizon Village Inc, located in Sanborn, NY, is a dedicated rehabilitation facility that provides long-term residential support and around-the-clock care for adult males dealing with substance abuse issues. The program integrates 12-step methodologies, techniques for managing anger, and concise intervention strategies to effectively tackle addiction challenges. This center serves adult men, including seniors and younger adults, fostering a nurturing atmosphere specifically oriented towards male clientele. With an emphasis on individualized care and specialized programs, Horizon Village Inc distinguishes itself as a well-rounded rehabilitation center committed to assisting individuals in their recovery journey from addiction.

Hospital of the University of Penn

The Hospital of the University of Penn, situated in Philadelphia, PA, provides thorough detoxification programs for adults and young adults. They emphasize personalized treatment, offering continuous inpatient detoxification with diverse methods like 12-step facilitation, anger management, and brief intervention. This center welcomes both male and female individuals, fostering a welcoming atmosphere. For those needing detoxification or specific treatment plans, the Hospital of the University of Penn is committed to delivering excellent care to support recovery.

Hotel California by the Sea

Hotel California by the Sea, located in Kirkland, WA, provides a wide array of rehabilitation options for both adults and young adults dealing with substance use challenges and concurrent mental health conditions. The facility features tailored programs for adult men, women, and those who have faced intimate partner violence. It offers various services including long-term residential programs, detoxification, and round-the-clock treatment support. By employing proven methods such as 12-step guidance, anger management, and cognitive behavioral therapy, the center prioritizes customized care for each individual. Committed to high standards and personalized recovery paths, Hotel California by the Sea strives to aid clients in their healing process.

Hotel California by the Sea

Hotel California by the Sea, located in Kirkland, WA, specializes in extensive addiction support for both adults and young adults. This center offers long-term residential care, detox programs, and round-the-clock residential services. Emphasizing a 12-step approach alongside anger management and cognitive behavioral therapy, the facility addresses the needs of clients dealing with simultaneous substance use and significant mental health challenges. Tailored programs are designed for adult men, adult women, and individuals who have faced intimate partner violence. With a commitment to personalized treatment, this center fosters a nurturing atmosphere for clients of all genders pursuing recovery.

Horizon Health Services Inc

Horizon Health Services Inc, situated in Lockport, NY, provides a variety of outpatient services aimed at treating substance use issues and co-existing mental health challenges in both adults and youth. The center is adept in 12-step approaches, anger management techniques, and short-term interventions, ensuring that each patient receives customized support. Additionally, Horizon Health Services Inc features specific programs designed for active military personnel, adolescents, and adult males, addressing the needs of various groups. Patients can access outpatient treatments including methadone, buprenorphine, or naltrexone, as the facility emphasizes the importance of high-quality care for all individuals pursuing recovery.

Horizons Mental Health Center Inc

Horizons Mental Health Center Inc, located in Hutchinson, KS, provides outpatient services aimed at addressing substance use and co-occurring mental health issues for both adults and children. This center features customized programs specifically designed for adolescents, women, and individuals who have faced traumatic experiences, ensuring that care meets diverse needs. Among the therapeutic methods utilized are anger management, brief interventions, and cognitive behavioral therapy. Catering to adults and elderly clients regardless of gender, the center also offers outpatient options for methadone/buprenorphine or naltrexone treatment in addition to standard outpatient programs. Clients can anticipate exceptional care within a nurturing setting that emphasizes comprehensive healing and recovery.

Horizon Health Services Inc

Horizon Health Services Inc, situated in Buffalo, NY, delivers thorough addiction treatment and targeted support for those facing combined substance use and significant mental health challenges. The center features intensive outpatient programs, general outpatient services, and medication-assisted treatment options including methadone, buprenorphine, and naltrexone. Emphasis is placed on 12-step encouragement, strategies for managing anger, and brief therapeutic interventions, ensuring each person's treatment plan is personalized. Services are available for active military members, young people, and adult men, accommodating adults and children/adolescents across all genders. Horizon Health Services Inc is committed to offering superior care and assistance to guide individuals toward lasting recovery.

Horizon Health Services Inc

Horizon Health Services Inc, located in Niagara Falls, NY, provides a wide range of treatment options for substance use issues, with a particular focus on treating dual diagnoses that involve both substance use disorders and significant mental health challenges in adults, as well as addressing severe emotional issues in children. The center offers extensive outpatient programs, including methadone, buprenorphine, or naltrexone treatments. Their therapeutic methods encompass 12-step support, anger management, and brief intervention techniques. They have specifically designed programs for active military personnel, teenagers, and adult males, ensuring that services are accessible to individuals of all genders, including seniors. Horizon Health Services Inc is committed to delivering high-quality care and assistance to those pursuing a path to recovery.

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San Francisco, CA

Horizons Unlimited located in San Francisco, CA, provides outpatient programs for substance use treatment aimed at adults, seniors, and young adults regardless of gender. The center is known for its expertise in brief intervention techniques, cognitive behavioral therapy, and the application of motivational incentives and contingency management. It particularly emphasizes support for clients who have a history of trauma and those facing concurrent mental health and substance use challenges. With dedicated programs for adolescents, Horizons Unlimited ensures that younger clients receive appropriate care. Their dedication to offering personalized and high-quality treatment options establishes them as a leading provider of addiction recovery services in the San Francisco region.

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In Albany, NY, Hospitality House TC Inc specializes in delivering comprehensive substance use therapies for both adults and children facing complex mental health challenges. The center offers both long-term and short-term residential programs, incorporating strategies such as 12-step facilitation, anger management, and brief intervention techniques. This facility is designed to support adult men, active military members, and those who have gone through intimate partner violence. It provides targeted care for seniors, young adults, and adults, ensuring a nurturing atmosphere for recovery in a male-only setting at Hospitality House TC Inc.

Frequently Asked Questions

What is buprenorphine and how does it treat opioid addiction?
Buprenorphine is a partial opioid agonist medication approved by the FDA for treating opioid use disorder. It binds to the same receptors as heroin and fentanyl but produces a much weaker effect, reducing cravings and withdrawal symptoms without causing intense euphoria. Buprenorphine has a ceiling effect, meaning its opioid effects plateau at moderate doses, making it safer than methadone in terms of overdose risk.
What is the difference between Suboxone and Subutex?
Suboxone contains two active ingredients — buprenorphine and naloxone — while Subutex contains only buprenorphine without naloxone. The naloxone in Suboxone is included as an abuse deterrent; it remains inactive when taken sublingually as prescribed but triggers withdrawal if the medication is injected. Subutex is generally reserved for patients who cannot tolerate naloxone, such as pregnant women.
What is a Sublocade injection and how does it work?
Sublocade is a once-monthly injectable form of buprenorphine administered as a subcutaneous injection in the abdominal area. After injection, the medication forms a solid deposit under the skin that slowly releases buprenorphine over the course of a month. This eliminates daily dosing and removes the possibility of missed doses or medication diversion.
What are the common side effects of Suboxone?
Common Suboxone side effects include headache, nausea, constipation, insomnia, sweating, and mouth numbness or pain from sublingual administration. Some patients also experience dizziness, drowsiness, and blurred vision, particularly when starting treatment. Most side effects diminish within the first few weeks as the body adjusts. Patients should report difficulty breathing or signs of allergic reaction immediately.
What happens during Suboxone withdrawal?
Suboxone withdrawal occurs when a patient stops taking the medication abruptly after prolonged use, with symptoms including muscle aches, anxiety, insomnia, nausea, and irritability. A medically supervised taper is strongly recommended, typically reducing the dose by small increments over weeks or months. The risk of opioid relapse is significantly higher during unsupervised discontinuation.
How does Suboxone compare to methadone?
Suboxone and methadone are both effective for opioid use disorder but differ in key ways. Methadone is a full opioid agonist dispensed daily at licensed clinics, while Suboxone is a partial agonist that can be prescribed by qualified physicians and taken at home. Suboxone carries a lower overdose risk due to its ceiling effect and offers greater convenience, though methadone may be more appropriate for patients with severe, long-standing dependence.
How can I find a Suboxone clinic or doctor near me?
The most reliable way to find a Suboxone provider is through SAMHSA's online treatment locator at findtreatment.gov, which allows you to search by location and filter for buprenorphine providers. Many primary care offices, addiction treatment centers, and telehealth platforms now offer Suboxone prescriptions following the elimination of the federal X-waiver requirement in early 2023.
What is Zubsolv and how is it different from Suboxone?
Zubsolv is a brand-name buprenorphine and naloxone sublingual tablet that features a mint flavor and dissolves faster under the tongue than other options. Due to its higher bioavailability, Zubsolv uses different dosing strengths — a Zubsolv 5.7 mg/1.4 mg tablet is considered equivalent to a Suboxone 8 mg/2 mg dose. Patients switching between products should work closely with their prescriber for correct dose conversion.
Does Medicaid cover Suboxone treatment?
Yes — Medicaid covers buprenorphine (including Suboxone, Sublocade, Subutex, Zubsolv, and Brixadi) for opioid use disorder in all 50 states, as required by the SUPPORT Act of 2018. Medicaid is the largest single payer for MAT in the US. Coverage details vary by state — some require prior authorization or limit certain formulations. Many OBOT clinics accept Medicaid directly; telehealth Suboxone providers also bill Medicaid in most states. Bring your Medicaid card to your intake appointment.
Can I get Suboxone through telehealth?
Yes. After the MAT Act of 2023 permanently eliminated the X-waiver requirement, any licensed prescriber can prescribe Suboxone via telehealth in most states. The DEA also extended COVID-era telehealth flexibilities through at least 2025, allowing virtual Suboxone induction without a prior in-person visit. Several specialty platforms — Bicycle Health, Ophelia, Workit Health, Boulder Care — offer Medicaid-accepting telehealth Suboxone treatment. Telehealth has dramatically expanded access in rural and underserved areas with no nearby OBOT physicians.

About Buprenorphine (Suboxone)

Buprenorphine is classified as a partial opioid agonist, meaning it activates opioid receptors in the brain but to a much lesser degree than full agonists such as heroin, fentanyl, or oxycodone. This partial activation suppresses withdrawal symptoms and reduces cravings without producing dangerous respiratory depression or intense euphoria. Buprenorphine also has an unusually high binding affinity for the mu-opioid receptor, effectively blocking other opioids from attaching — providing a protective effect against relapse-related overdose.

How Buprenorphine Works

One of the defining features of buprenorphine is its ceiling effect — after a certain dose threshold, increasing the amount does not produce additional opioid effects. This dramatically reduces the risk of fatal overdose compared to methadone or illicit opioids. The ceiling effect, combined with its long duration of action (24 to 72 hours), makes buprenorphine one of the safest and most effective tools in medication-assisted treatment (MAT). Approved by the FDA in 2002, buprenorphine was a breakthrough because it could be prescribed in outpatient settings rather than requiring daily clinic visits.

Buprenorphine Brand Comparison: Suboxone, Subutex, Sublocade, Zubsolv, Brixadi

Buprenorphine is available under several FDA-approved brand names, each with distinct formulations, dosing schedules, and clinical use cases. The comparison below highlights the key differences:

BrandActive ingredientFormFrequencySettingFDA yearBest for
SuboxoneBuprenorphine + naloxoneSublingual film / tabletDailyOBOT, telehealth, retail pharmacy2002Most prescribed; naloxone deters injection misuse
SubutexBuprenorphine (alone)Sublingual tabletDailyOBOT2002Pregnancy; documented naloxone sensitivity
SublocadeBuprenorphine extended-releaseSubcutaneous injection (ATRIGEL depot)MonthlyClinic-administered2017No daily dosing; eliminates diversion risk
ZubsolvBuprenorphine + naloxoneSublingual tablet (higher bioavailability)DailyOBOT2013Faster dissolution; mint flavor; lower mg/dose
BrixadiBuprenorphine extended-releaseSubcutaneous injectionWeekly or monthlyClinic2023Newer alternative to Sublocade; weekly option for induction

All five medications are Schedule III controlled substances and equivalent in clinical efficacy at appropriate doses. The choice depends on adherence patterns, lifestyle, insurance coverage, and clinical context (e.g., pregnancy, prior injection use, daily-dosing burden). Many patients begin on sublingual Suboxone for stabilization and transition to monthly Sublocade or weekly Brixadi after sustained recovery.

Buprenorphine Side Effects

Common buprenorphine side effects include:

  • Headache and dizziness
  • Nausea and vomiting, especially during induction
  • Constipation and insomnia
  • Excessive sweating
  • Mouth numbness or oral discomfort from sublingual formulations

More serious side effects may include respiratory depression (particularly when combined with benzodiazepines or alcohol), liver problems, and allergic reactions. For most patients, side effects are mild and resolve within one to two weeks. The benefits in preventing relapse and overdose death significantly outweigh the risks.

Buprenorphine Dosage and Induction

Treatment begins with an induction phase where the patient must be in mild to moderate opioid withdrawal. Common induction doses range from 2 mg to 8 mg on the first day, with increases over the following days. Most patients stabilize on 8 mg to 24 mg per day, with 16 mg being the most commonly prescribed dose. Research suggests doses of 16 mg or higher are associated with better retention and outcomes. Dosage should always be adjusted under medical supervision.

Buprenorphine/Naloxone Combination

Many buprenorphine formulations include naloxone as an abuse deterrent. When taken sublingually as directed, naloxone has very low bioavailability and produces no clinical effect. However, if someone attempts to inject the medication, the naloxone component becomes fully active and triggers severe withdrawal. This design discourages injection misuse while having no impact on patients who take the medication correctly. The combination is the standard first-line formulation for opioid addiction treatment.

Suboxone: Sublingual Buprenorphine

Suboxone is the most recognized brand name for buprenorphine-naloxone and is most commonly dispensed as a sublingual film (Suboxone strips) that dissolves under the tongue. Suboxone has transformed opioid treatment by enabling millions of patients to receive effective pharmacotherapy in outpatient settings without the daily clinic visits required by methadone programs.

Suboxone Side Effects

Commonly reported Suboxone side effects include headache, nausea, tongue or mouth irritation, constipation, insomnia, sweating, and decreased libido. The sublingual film can cause irritation or small sores inside the mouth — rotating placement between under the tongue and against the cheek helps minimize this. Patients should not eat, drink, or smoke while the film is dissolving.

Suboxone Strips: Film vs. Tablet

Suboxone strips (sublingual film) have largely replaced the original tablet form. The film dissolves more quickly (two to four minutes), provides more consistent absorption, and is harder to divert due to individual foil packaging. Generic buprenorphine-naloxone tablets are often less expensive and may be preferred for cost reasons. Both are therapeutically equivalent when taken as prescribed.

Suboxone Treatment Programs

Comprehensive Suboxone treatment typically includes three phases:

  • Induction: Initial dosing under medical supervision, requiring the patient to be in early withdrawal
  • Stabilization: Dose adjustment until cravings and withdrawal are minimal, usually one to two months
  • Maintenance: Stable dosing for an extended period — often a year or longer — combined with counseling and behavioral therapy

Evidence consistently shows that longer treatment durations are associated with better outcomes. Most addiction medicine experts recommend a minimum of one to two years of maintenance therapy.

Find a Suboxone Clinic Near You — OBOT & Telehealth Options

Finding a Suboxone clinic has become significantly easier since the federal government eliminated the X-waiver requirement in January 2023, meaning any provider with a standard DEA license can now prescribe Suboxone. Patients can search SAMHSA's treatment locator at findtreatment.gov or use our directory to locate nearby facilities that offer buprenorphine-based treatment.

Suboxone Doctors Near Me

Beyond SAMHSA's locator, many state health departments maintain directories of addiction treatment providers. Telehealth has dramatically expanded access — several platforms now offer virtual Suboxone consultations, which is especially valuable for patients in rural areas. When selecting a provider, look for those offering comprehensive treatment including counseling, not just medication prescriptions.

Suboxone Withdrawal and Tapering

Suboxone withdrawal can include muscle aches, anxiety, insomnia, nausea, sweating, and intense opioid cravings. A gradual, medically supervised taper is recommended — typically reducing the dose by 10 to 25 percent every one to four weeks. Slower tapers over several months produce fewer symptoms and lower relapse rates. There is no medically mandated time limit for Suboxone treatment, and many patients benefit from indefinite maintenance.

Suboxone vs Methadone

Suboxone can be prescribed in office settings and taken at home, carries lower overdose risk due to its ceiling effect, and offers greater scheduling flexibility. Methadone is a full agonist that may be more effective for severe, long-standing dependence but must be dispensed at licensed clinics with daily visits. Neither is inherently superior — the best choice keeps the patient in treatment. Some patients may also benefit from naltrexone, a non-opioid alternative.

Sublocade: Monthly Buprenorphine Injection

Sublocade delivers buprenorphine as a once-monthly subcutaneous injection in the abdominal area using the ATRIGEL delivery system, which forms a solid biodegradable depot that slowly releases medication. Patients must first stabilize on sublingual buprenorphine (8 mg+ daily) for at least seven days. Treatment typically begins with two 300 mg injections, followed by maintenance on 300 mg or 100 mg. Sublocade eliminates concerns about daily adherence, missed doses, and medication diversion.

Sublocade Side Effects

The most common Sublocade side effects are injection-site reactions (pain, itching, redness, or a noticeable lump), nausea, constipation, headache, and fatigue. The injection-site lump is normal and gradually diminishes as medication is absorbed. Patients should avoid rubbing or massaging the site. Elevated liver enzymes may also occur but are usually mild and transient.

Subutex: Buprenorphine Without Naloxone

Subutex was the original brand-name buprenorphine product. While the brand has been discontinued, generic buprenorphine-only tablets remain available. Buprenorphine monotherapy is typically reserved for pregnant patients (to avoid naloxone exposure to the fetus), patients with documented naloxone sensitivity, or sometimes during the induction phase before transitioning to the combination product.

Subutex vs Suboxone

The primary difference is the absence of naloxone in Subutex. Because Subutex lacks the abuse-deterrent naloxone component, it may carry slightly higher diversion risk, and many insurance formularies prioritize the combination as the default. Current clinical guidelines favor buprenorphine-only formulations primarily for pregnancy and naloxone sensitivity.

Zubsolv: Alternative Buprenorphine Brand

Zubsolv is a buprenorphine-naloxone sublingual tablet featuring a mint flavor and faster dissolution (under two minutes). Due to enhanced bioavailability, Zubsolv uses different dose strengths — a 5.7 mg/1.4 mg tablet equals a Suboxone 8 mg/2 mg dose. Zubsolv is available in multiple strengths for flexible dosing during both induction and maintenance.

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Medically Reviewed Updated August 2026

Reviewed by licensed addiction specialists. Information reflects current clinical guidance.

Sources:SAMHSA·NIDA·CDC

Need immediate help? Call SAMHSA: 1-800-662-4357 (24/7, free)