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Medically Reviewed Content
Updated: August 2026
Sources: SAMHSA, NIDA

Suboxone Clinic Near You: Buprenorphine Treatment for Opioid Addiction

Find a Suboxone clinic near you. Buprenorphine — sold under brand names Suboxone, Sublocade, Subutex, Zubsolv, and Brixadi — is the most-prescribed MAT for opioid use disorder. It is a partial mu-opioid agonist with a ceiling effect that dramatically reduces overdose risk vs. methadone. After the MAT Act of 2023 eliminated the X-waiver requirement, any licensed prescriber can prescribe buprenorphine in office-based settings (OBOT), via telehealth, or at retail pharmacies. Buprenorphine is a Schedule III controlled substance and is covered by Medicaid in all 50 states.

Found 7,145 treatment centers offering buprenorphine (suboxone) across the United States.

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Huntingdon Valley Comp Trt Center

Huntingdon Valley Comp Trt Center, located in Huntingdon Valley, PA, provides outpatient detox services, treatments for substance use disorders, and options for methadone, buprenorphine, or naltrexone therapy. Their offerings include programs for anger management, cognitive behavioral therapy, and motivational interviewing. This facility serves adult men and women, including individuals affected by intimate partner or domestic violence. Catering to both adults and young adults of all genders, the center emphasizes specialized care in a supportive atmosphere. With a commitment to evidence-based practices, the center guarantees high-quality treatment for individuals pursuing recovery from substance use challenges.

Huntington Comprehensive Trt Ctr

Situated in Huntington, WV, the Huntington Comprehensive Trt Ctr delivers a variety of outpatient services designed for adults and young adults dealing with substance use issues alongside mental health challenges. The center focuses on detoxification, treatment for substance use, and support for individuals facing severe mental health conditions. Services include outpatient detox, as well as medication-assisted treatments using methadone, buprenorphine, and naltrexone. Their approach combines 12-step facilitation, anger management strategies, and brief intervention methods to aid recovery. With dedicated programs for adult men, adult women, and individuals with co-occurring disorders, the center prioritizes personalized care that addresses the specific requirements of each client.

Huntington Creek Recovery Center

Huntington Creek Recovery Center, situated in Shickshinny, PA, provides a wide array of services for individuals battling addiction. With a focus on both detoxification and treatment for substance use disorders, the center offers options such as residential detox, continuous care, and short-term programs. Utilizing effective methodologies like 12-step support, anger management strategies, and cognitive behavioral therapy, the facility serves a diverse clientele, including adults, teenagers, and military personnel. Customized programs designed for adult men, women, and youths ensure that each individual receives the care they need. Huntington Creek Recovery Center is recognized for its high-quality services and varied specialized offerings, making it an excellent option for those in search of tailored addiction recovery solutions.

Huntsville Metro Treatment Center

Huntsville Metro Treatment Center, situated in Huntsville, AL, provides outpatient detox and substance abuse treatment options for both adults and young adults. The facility extends its specialized services to active duty military members, as well as adult men and women. Employing a variety of treatment strategies, including anger management, brief intervention, and cognitive behavioral therapy, the center prioritizes high-quality care. It offers outpatient treatment using methadone/buprenorphine or naltrexone, catering to both male and female clients. Huntsville Metro Treatment Center is committed to delivering effective and holistic addiction recovery services in a nurturing setting.

Icarus Behavioral Health

Icarus Behavioral Health, located in Rio Rancho, NM, provides extensive treatment for substance use and focuses on adults grappling with severe mental health challenges. Their offerings include long-term and short-term programs, as well as residential options, all designed to create a nurturing space for recovery. Utilizing customized strategies such as anger management, cognitive behavioral therapy, and targeted brief interventions, this center prioritizes individualized support. They also have specialized programs tailored for men, women, and clients facing dual diagnoses. Catering to both adults and young adults, Icarus Behavioral Health is committed to delivering exceptional care that aids individuals in achieving sobriety and improved mental health.

Icarus Behavioral Health

Icarus Behavioral Health, located in Albuquerque, NM, specializes in providing thorough treatment for substance use issues in both adults and young adults, particularly those who also face mental health challenges. The center features a variety of programs including intensive outpatient, outpatient, and day treatment, all grounded in proven methods like cognitive behavioral therapy and anger management strategies. It also offers specialized programs for men and women, as well as those dealing with dual diagnoses. Committed to delivering high-quality care, Icarus Behavioral Health customizes its treatment plans to meet the unique requirements of each individual, fostering a nurturing atmosphere conducive to recovery. This facility is open to both male and female clients seeking reliable rehabilitation options within a supportive environment.

Icarus Behavioral Health

Situated in Rio Rancho, NM, Icarus Behavioral Health provides an extensive variety of treatment options for both adults and young adults facing challenges related to substance abuse and concurrent mental health conditions. The center emphasizes various forms of care, including long-term, short-term, and around-the-clock residential programs. It offers targeted services such as anger management, cognitive behavioral therapy, and short-term interventions. Distinctive programs designed for adult men, adult women, and those with co-occurring disorders guarantee customized and effective treatment. Icarus Behavioral Health is recognized for its dedication to high-quality care and a personalized strategy to support individuals in achieving sustained recovery.

Illinois Recovery Center LLC

Illinois Recovery Center LLC, situated in Belleville, IL, delivers extensive support for individuals battling addiction. This establishment offers services for drug and alcohol withdrawal, ongoing substance use disorder treatment, and dedicated assistance for those facing both addiction and significant mental health challenges. Through various levels of care including outpatient programs, intensive day treatment, partial hospitalization, and inpatient detox, the center adapts to a wide spectrum of recovery requirements. Their therapeutic methods incorporate 12-step program support, strategies for managing anger, and brief intervention strategies. Tailored programs are provided for active duty military, adult men, and adult women. Catering to adults and young adults across all gender identities, Illinois Recovery Center LLC is committed to providing exceptional care customized for each person's unique journey.

Illuminate Recovery LLC

Illuminate Recovery LLC, located in Scottsdale, AZ, provides a variety of scientifically-supported therapies for adults and children dealing with substance use issues and related mental health challenges. The center's offerings include intensive outpatient programs, day treatment, and partial hospitalization. Illuminate Recovery LLC also features tailored services for adult men, women, and those affected by intimate partner violence, addressing a spectrum of requirements. Their treatment modalities encompass 12-step facilitation, anger management techniques, and cognitive behavioral therapy. Committed to delivering exceptional care, this facility focuses on customized treatment strategies to assist individuals of all genders in their recovery journey.

Imagine Recovery
New Orleans, LA

Imagine Recovery in New Orleans, LA, specializes in treating substance use disorders and co-occurring mental health challenges for individuals of all ages. The center delivers comprehensive care through intensive outpatient, standard outpatient, and day treatment programs. Their therapeutic modalities include 12-step facilitation, anger management techniques, and brief intervention strategies, all personalized to each client's unique circumstances. Notably, Imagine Recovery offers distinct programs designed for adult men, adult women, and individuals with a history of trauma. Catering to adults and young adults across the gender spectrum, the facility is committed to providing high-quality, evidence-based services that foster enduring recovery.

Immersion Residential
Boynton Beach, FL

Situated in Boynton Beach, Florida, Immersion Residential provides an extensive array of addiction recovery services. This center is dedicated to residential detox and around-the-clock supervision for both adults and young adults. Emphasizing 12-step support, anger management, and short intervention strategies, it offers customized programs designed for adult males and females, including those who have faced intimate partner violence. Immersion Residential is distinguished by its personalized care and dedication to high standards, positioning itself as an excellent option for individuals in need of effective and compassionate substance abuse treatment.

Icarus Behavioral Health

Icarus Behavioral Health, located in Las Vegas, NV, provides a wide range of treatment options for adults grappling with substance use disorders alongside significant mental health challenges. The center features various programs, including intensive outpatient, long-term residential, and standard outpatient care, designed to meet diverse therapeutic requirements. Through techniques such as cognitive behavioral therapy, anger management, and motivational incentives, the facility is dedicated to offering personalized support to each individual. The center also has specialized programs for adult men, women, and those dealing with co-occurring issues, reflecting a strong commitment to customized treatment plans. Icarus Behavioral Health is open to adults and young adults of any gender, emphasizing a holistic approach to healing and recovery.

IBH Addiction Recovery

Situated in Akron, Ohio, IBH Addiction Recovery delivers thorough care for substance use disorders and provides targeted interventions for individuals facing dual diagnoses of mental health conditions. They feature intensive outpatient, standard outpatient, and day treatment modalities, employing proven therapeutic techniques like 12-step support and emotional regulation strategies. Emphasizing a trauma-sensitive approach, IBH Addiction Recovery serves adults of all genders and young adults. Patients receive individualized care plans and high-quality support within a nurturing setting designed to meet their specific requirements.

Impact Counseling Services LLC

Impact Counseling Services LLC in Hollidaysburg, PA, provides thorough outpatient services for individuals of all ages grappling with substance abuse and intertwined mental health challenges. They feature tailored programs designed for teenagers and those experiencing dual diagnoses. Through a concentration on techniques such as anger management, cognitive behavioral therapy, and motivational interviewing, this establishment customizes therapeutic approaches to suit each person's unique requirements. Delivering outpatient pharmacotherapy options including methadone, buprenorphine, or naltrexone, alongside standard outpatient therapy, Impact Counseling Services supports both male and female patients in their pursuit of effective, research-backed treatment for addiction and psychological well-being.

IL Institute for Addiction Recovery

The IL Institute for Addiction Recovery, situated in Peoria, IL, provides extensive support for individuals battling addiction. Their specialized services include hospital-based inpatient detoxification and treatment for various substance use disorders. Employing evidence-based strategies such as 12-step facilitation, cognitive behavioral therapy, and brief interventions, they deliver tailored care to adult men and women. Distinctive programs are available for those who have faced intimate partner or domestic violence. This center also offers gender-specific treatment for both adult and young adult female and male patients. Committed to high-quality, individualized recovery plans, the IL Institute for Addiction Recovery is devoted to fostering long-term healing.

ICAN Community Services Inc

ICAN Community Services Inc, situated in South Holland, IL, delivers thorough substance abuse care for adults and young adults. The facility offers intensive outpatient programs, general outpatient services, and medication-assisted treatment utilizing methadone, buprenorphine, or naltrexone. Their approach incorporates brief intervention, cognitive behavioral therapy, and relapse prevention strategies, with personalized treatment plans for each individual. Specialized support is available for adolescents, adult men, and adult women. ICAN Community Services Inc is dedicated to providing high-quality treatment for all clients, serving as a key provider for addiction recovery in the South Holland community.

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Humboldt Recovery Center Inc, located in Eureka, CA, provides focused addiction treatment services for adult women within a nurturing setting. The center offers diverse treatment modalities, encompassing extended stay residential, round-the-clock residential, and brief residential programs. Emphasizing 12-step integration, emotional regulation techniques, and cognitive behavioral approaches, the facility personalizes treatment to address distinct requirements. Humboldt Recovery Center Inc distinguishes itself with unique offerings for adult women, particularly those with histories of domestic violence or sexual trauma. Catering to a broad age range from young adults to seniors, this institution is dedicated to delivering excellent care and extensive assistance to women on their path to recovery.

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Rochester, NY

Huther Doyle, situated in Rochester, NY, provides extensive outpatient care for individuals of all ages dealing with substance use, detoxification, and co-occurring mental health conditions. Their expertise includes outpatient detox, medication-assisted treatment (methadone/buprenorphine), and therapeutic interventions such as anger management and cognitive behavioral therapy. The center is dedicated to serving specific populations including adolescents, women, and those affected by trauma, ensuring tailored, high-quality support for everyone pursuing a life of recovery.

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Morocco, IN

IFC Clinics, located in Morocco, IN, provides an extensive array of services aimed at treating addiction for both adults and young individuals. The facility offers detox services and specialized treatment for substance use, with a focus on individuals facing dual challenges of substance use disorders and severe mental health issues in adults, as well as significant emotional disturbances in minors. Treatment options include intensive outpatient programs, outpatient care, and day treatment, allowing the center to customize its services based on individual requirements. Employing evidence-based methods such as 12-step programs, brief interventions, and cognitive behavioral therapy, IFC Clinics maintains a high standard of care. The center has specialized initiatives for adult men, adult women, and those dealing with concurrent mental health and substance use issues. IFC Clinics is open to male and female clients, providing assistance to a broad spectrum of individuals on their path to recovery.

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Im Still Standing by Grace in Brooklyn, MD, provides extensive addiction recovery services for adults and young adults. They offer detox, substance abuse treatment, and various living options like transitional housing, halfway houses, and sober living. Treatment is available in formats such as intensive outpatient, long-term residential, and outpatient programs. The center employs specialized therapeutic methods, including 12-step facilitation, anger management, and brief interventions, customized for each person's journey. Serving specific groups like active military personnel, adult men, and adult women, Im Still Standing by Grace is equipped to support a wide array of individuals in their pursuit of lasting recovery.

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Impact Counseling Service, located in Ebensburg, PA, specializes in outpatient treatment for substance use tailored for both adults and seniors. The center offers treatments such as outpatient methadone/buprenorphine or naltrexone, in addition to various therapeutic methods like 12-step facilitation, anger management, and brief interventions. The program is designed to assist adolescents, those who have faced trauma, and individuals managing both mental health and substance use disorders. Impact Counseling Service accommodates clients of all genders, promoting a holistic and inclusive approach to recovery. Committed to delivering high-quality care with customized programs, this center serves as a vital resource for individuals in search of effective addiction treatment solutions.

Frequently Asked Questions

What is buprenorphine and how does it treat opioid addiction?
Buprenorphine is a partial opioid agonist medication approved by the FDA for treating opioid use disorder. It binds to the same receptors as heroin and fentanyl but produces a much weaker effect, reducing cravings and withdrawal symptoms without causing intense euphoria. Buprenorphine has a ceiling effect, meaning its opioid effects plateau at moderate doses, making it safer than methadone in terms of overdose risk.
What is the difference between Suboxone and Subutex?
Suboxone contains two active ingredients — buprenorphine and naloxone — while Subutex contains only buprenorphine without naloxone. The naloxone in Suboxone is included as an abuse deterrent; it remains inactive when taken sublingually as prescribed but triggers withdrawal if the medication is injected. Subutex is generally reserved for patients who cannot tolerate naloxone, such as pregnant women.
What is a Sublocade injection and how does it work?
Sublocade is a once-monthly injectable form of buprenorphine administered as a subcutaneous injection in the abdominal area. After injection, the medication forms a solid deposit under the skin that slowly releases buprenorphine over the course of a month. This eliminates daily dosing and removes the possibility of missed doses or medication diversion.
What are the common side effects of Suboxone?
Common Suboxone side effects include headache, nausea, constipation, insomnia, sweating, and mouth numbness or pain from sublingual administration. Some patients also experience dizziness, drowsiness, and blurred vision, particularly when starting treatment. Most side effects diminish within the first few weeks as the body adjusts. Patients should report difficulty breathing or signs of allergic reaction immediately.
What happens during Suboxone withdrawal?
Suboxone withdrawal occurs when a patient stops taking the medication abruptly after prolonged use, with symptoms including muscle aches, anxiety, insomnia, nausea, and irritability. A medically supervised taper is strongly recommended, typically reducing the dose by small increments over weeks or months. The risk of opioid relapse is significantly higher during unsupervised discontinuation.
How does Suboxone compare to methadone?
Suboxone and methadone are both effective for opioid use disorder but differ in key ways. Methadone is a full opioid agonist dispensed daily at licensed clinics, while Suboxone is a partial agonist that can be prescribed by qualified physicians and taken at home. Suboxone carries a lower overdose risk due to its ceiling effect and offers greater convenience, though methadone may be more appropriate for patients with severe, long-standing dependence.
How can I find a Suboxone clinic or doctor near me?
The most reliable way to find a Suboxone provider is through SAMHSA's online treatment locator at findtreatment.gov, which allows you to search by location and filter for buprenorphine providers. Many primary care offices, addiction treatment centers, and telehealth platforms now offer Suboxone prescriptions following the elimination of the federal X-waiver requirement in early 2023.
What is Zubsolv and how is it different from Suboxone?
Zubsolv is a brand-name buprenorphine and naloxone sublingual tablet that features a mint flavor and dissolves faster under the tongue than other options. Due to its higher bioavailability, Zubsolv uses different dosing strengths — a Zubsolv 5.7 mg/1.4 mg tablet is considered equivalent to a Suboxone 8 mg/2 mg dose. Patients switching between products should work closely with their prescriber for correct dose conversion.
Does Medicaid cover Suboxone treatment?
Yes — Medicaid covers buprenorphine (including Suboxone, Sublocade, Subutex, Zubsolv, and Brixadi) for opioid use disorder in all 50 states, as required by the SUPPORT Act of 2018. Medicaid is the largest single payer for MAT in the US. Coverage details vary by state — some require prior authorization or limit certain formulations. Many OBOT clinics accept Medicaid directly; telehealth Suboxone providers also bill Medicaid in most states. Bring your Medicaid card to your intake appointment.
Can I get Suboxone through telehealth?
Yes. After the MAT Act of 2023 permanently eliminated the X-waiver requirement, any licensed prescriber can prescribe Suboxone via telehealth in most states. The DEA also extended COVID-era telehealth flexibilities through at least 2025, allowing virtual Suboxone induction without a prior in-person visit. Several specialty platforms — Bicycle Health, Ophelia, Workit Health, Boulder Care — offer Medicaid-accepting telehealth Suboxone treatment. Telehealth has dramatically expanded access in rural and underserved areas with no nearby OBOT physicians.

About Buprenorphine (Suboxone)

Buprenorphine is classified as a partial opioid agonist, meaning it activates opioid receptors in the brain but to a much lesser degree than full agonists such as heroin, fentanyl, or oxycodone. This partial activation suppresses withdrawal symptoms and reduces cravings without producing dangerous respiratory depression or intense euphoria. Buprenorphine also has an unusually high binding affinity for the mu-opioid receptor, effectively blocking other opioids from attaching — providing a protective effect against relapse-related overdose.

How Buprenorphine Works

One of the defining features of buprenorphine is its ceiling effect — after a certain dose threshold, increasing the amount does not produce additional opioid effects. This dramatically reduces the risk of fatal overdose compared to methadone or illicit opioids. The ceiling effect, combined with its long duration of action (24 to 72 hours), makes buprenorphine one of the safest and most effective tools in medication-assisted treatment (MAT). Approved by the FDA in 2002, buprenorphine was a breakthrough because it could be prescribed in outpatient settings rather than requiring daily clinic visits.

Buprenorphine Brand Comparison: Suboxone, Subutex, Sublocade, Zubsolv, Brixadi

Buprenorphine is available under several FDA-approved brand names, each with distinct formulations, dosing schedules, and clinical use cases. The comparison below highlights the key differences:

BrandActive ingredientFormFrequencySettingFDA yearBest for
SuboxoneBuprenorphine + naloxoneSublingual film / tabletDailyOBOT, telehealth, retail pharmacy2002Most prescribed; naloxone deters injection misuse
SubutexBuprenorphine (alone)Sublingual tabletDailyOBOT2002Pregnancy; documented naloxone sensitivity
SublocadeBuprenorphine extended-releaseSubcutaneous injection (ATRIGEL depot)MonthlyClinic-administered2017No daily dosing; eliminates diversion risk
ZubsolvBuprenorphine + naloxoneSublingual tablet (higher bioavailability)DailyOBOT2013Faster dissolution; mint flavor; lower mg/dose
BrixadiBuprenorphine extended-releaseSubcutaneous injectionWeekly or monthlyClinic2023Newer alternative to Sublocade; weekly option for induction

All five medications are Schedule III controlled substances and equivalent in clinical efficacy at appropriate doses. The choice depends on adherence patterns, lifestyle, insurance coverage, and clinical context (e.g., pregnancy, prior injection use, daily-dosing burden). Many patients begin on sublingual Suboxone for stabilization and transition to monthly Sublocade or weekly Brixadi after sustained recovery.

Buprenorphine Side Effects

Common buprenorphine side effects include:

  • Headache and dizziness
  • Nausea and vomiting, especially during induction
  • Constipation and insomnia
  • Excessive sweating
  • Mouth numbness or oral discomfort from sublingual formulations

More serious side effects may include respiratory depression (particularly when combined with benzodiazepines or alcohol), liver problems, and allergic reactions. For most patients, side effects are mild and resolve within one to two weeks. The benefits in preventing relapse and overdose death significantly outweigh the risks.

Buprenorphine Dosage and Induction

Treatment begins with an induction phase where the patient must be in mild to moderate opioid withdrawal. Common induction doses range from 2 mg to 8 mg on the first day, with increases over the following days. Most patients stabilize on 8 mg to 24 mg per day, with 16 mg being the most commonly prescribed dose. Research suggests doses of 16 mg or higher are associated with better retention and outcomes. Dosage should always be adjusted under medical supervision.

Buprenorphine/Naloxone Combination

Many buprenorphine formulations include naloxone as an abuse deterrent. When taken sublingually as directed, naloxone has very low bioavailability and produces no clinical effect. However, if someone attempts to inject the medication, the naloxone component becomes fully active and triggers severe withdrawal. This design discourages injection misuse while having no impact on patients who take the medication correctly. The combination is the standard first-line formulation for opioid addiction treatment.

Suboxone: Sublingual Buprenorphine

Suboxone is the most recognized brand name for buprenorphine-naloxone and is most commonly dispensed as a sublingual film (Suboxone strips) that dissolves under the tongue. Suboxone has transformed opioid treatment by enabling millions of patients to receive effective pharmacotherapy in outpatient settings without the daily clinic visits required by methadone programs.

Suboxone Side Effects

Commonly reported Suboxone side effects include headache, nausea, tongue or mouth irritation, constipation, insomnia, sweating, and decreased libido. The sublingual film can cause irritation or small sores inside the mouth — rotating placement between under the tongue and against the cheek helps minimize this. Patients should not eat, drink, or smoke while the film is dissolving.

Suboxone Strips: Film vs. Tablet

Suboxone strips (sublingual film) have largely replaced the original tablet form. The film dissolves more quickly (two to four minutes), provides more consistent absorption, and is harder to divert due to individual foil packaging. Generic buprenorphine-naloxone tablets are often less expensive and may be preferred for cost reasons. Both are therapeutically equivalent when taken as prescribed.

Suboxone Treatment Programs

Comprehensive Suboxone treatment typically includes three phases:

  • Induction: Initial dosing under medical supervision, requiring the patient to be in early withdrawal
  • Stabilization: Dose adjustment until cravings and withdrawal are minimal, usually one to two months
  • Maintenance: Stable dosing for an extended period — often a year or longer — combined with counseling and behavioral therapy

Evidence consistently shows that longer treatment durations are associated with better outcomes. Most addiction medicine experts recommend a minimum of one to two years of maintenance therapy.

Find a Suboxone Clinic Near You — OBOT & Telehealth Options

Finding a Suboxone clinic has become significantly easier since the federal government eliminated the X-waiver requirement in January 2023, meaning any provider with a standard DEA license can now prescribe Suboxone. Patients can search SAMHSA's treatment locator at findtreatment.gov or use our directory to locate nearby facilities that offer buprenorphine-based treatment.

Suboxone Doctors Near Me

Beyond SAMHSA's locator, many state health departments maintain directories of addiction treatment providers. Telehealth has dramatically expanded access — several platforms now offer virtual Suboxone consultations, which is especially valuable for patients in rural areas. When selecting a provider, look for those offering comprehensive treatment including counseling, not just medication prescriptions.

Suboxone Withdrawal and Tapering

Suboxone withdrawal can include muscle aches, anxiety, insomnia, nausea, sweating, and intense opioid cravings. A gradual, medically supervised taper is recommended — typically reducing the dose by 10 to 25 percent every one to four weeks. Slower tapers over several months produce fewer symptoms and lower relapse rates. There is no medically mandated time limit for Suboxone treatment, and many patients benefit from indefinite maintenance.

Suboxone vs Methadone

Suboxone can be prescribed in office settings and taken at home, carries lower overdose risk due to its ceiling effect, and offers greater scheduling flexibility. Methadone is a full agonist that may be more effective for severe, long-standing dependence but must be dispensed at licensed clinics with daily visits. Neither is inherently superior — the best choice keeps the patient in treatment. Some patients may also benefit from naltrexone, a non-opioid alternative.

Sublocade: Monthly Buprenorphine Injection

Sublocade delivers buprenorphine as a once-monthly subcutaneous injection in the abdominal area using the ATRIGEL delivery system, which forms a solid biodegradable depot that slowly releases medication. Patients must first stabilize on sublingual buprenorphine (8 mg+ daily) for at least seven days. Treatment typically begins with two 300 mg injections, followed by maintenance on 300 mg or 100 mg. Sublocade eliminates concerns about daily adherence, missed doses, and medication diversion.

Sublocade Side Effects

The most common Sublocade side effects are injection-site reactions (pain, itching, redness, or a noticeable lump), nausea, constipation, headache, and fatigue. The injection-site lump is normal and gradually diminishes as medication is absorbed. Patients should avoid rubbing or massaging the site. Elevated liver enzymes may also occur but are usually mild and transient.

Subutex: Buprenorphine Without Naloxone

Subutex was the original brand-name buprenorphine product. While the brand has been discontinued, generic buprenorphine-only tablets remain available. Buprenorphine monotherapy is typically reserved for pregnant patients (to avoid naloxone exposure to the fetus), patients with documented naloxone sensitivity, or sometimes during the induction phase before transitioning to the combination product.

Subutex vs Suboxone

The primary difference is the absence of naloxone in Subutex. Because Subutex lacks the abuse-deterrent naloxone component, it may carry slightly higher diversion risk, and many insurance formularies prioritize the combination as the default. Current clinical guidelines favor buprenorphine-only formulations primarily for pregnancy and naloxone sensitivity.

Zubsolv: Alternative Buprenorphine Brand

Zubsolv is a buprenorphine-naloxone sublingual tablet featuring a mint flavor and faster dissolution (under two minutes). Due to enhanced bioavailability, Zubsolv uses different dose strengths — a 5.7 mg/1.4 mg tablet equals a Suboxone 8 mg/2 mg dose. Zubsolv is available in multiple strengths for flexible dosing during both induction and maintenance.

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Medically Reviewed Updated August 2026

Reviewed by licensed addiction specialists. Information reflects current clinical guidance.

Sources:SAMHSA·NIDA·CDC

Need immediate help? Call SAMHSA: 1-800-662-4357 (24/7, free)