NWVCIL Logo
Medically Reviewed Content
Updated: August 2026
Sources: SAMHSA, NIDA

Suboxone Clinic Near You: Buprenorphine Treatment for Opioid Addiction

Find a Suboxone clinic near you. Buprenorphine — sold under brand names Suboxone, Sublocade, Subutex, Zubsolv, and Brixadi — is the most-prescribed MAT for opioid use disorder. It is a partial mu-opioid agonist with a ceiling effect that dramatically reduces overdose risk vs. methadone. After the MAT Act of 2023 eliminated the X-waiver requirement, any licensed prescriber can prescribe buprenorphine in office-based settings (OBOT), via telehealth, or at retail pharmacies. Buprenorphine is a Schedule III controlled substance and is covered by Medicaid in all 50 states.

Found 7,145 treatment centers offering buprenorphine (suboxone) across the United States.

Need Help Finding the Right Treatment Center?

Speak with a compassionate specialist now - 100% free & confidential

Call +1 (833) 244-3031
Available 24/7
All 50 States
Filters:

Showing 21 of 7145 results

Lakes Treatment Center Inc

Nestled in Copperopolis, CA, Lakes Treatment Center Inc is dedicated to providing a full spectrum of care for those battling substance use disorders and accompanying mental health conditions. They offer extended residential stays, detox services, and round-the-clock residential assistance. Their approach emphasizes 12-step principles, anger management techniques, and cognitive behavioral therapy, ensuring a personalized treatment plan for every client. Dedicated programs cater to adult men and women, as well as individuals affected by domestic violence or intimate partner abuse. Serving adults and young adults of all genders, Lakes Treatment Center Inc is committed to delivering exceptional, individualized support for sustained recovery.

Lakeside Academy
Buffalo, MN

Situated in Buffalo, MN, Lakeside Academy delivers a wide array of rehabilitation services specifically designed for adult males. This center offers various treatment options, including intensive outpatient therapy, long-term residential support, and standard outpatient programs. Lakeside Academy focuses on addressing substance use disorders, alongside concurrent mental health challenges and emotional issues in adolescents. Emphasizing techniques such as 12-step empowerment, anger management, and brief interventions, the center customizes its methods to meet the specific requirements of each individual. Specialized programs for teenagers, as well as for those who have experienced domestic violence and sexual abuse, distinguish Lakeside Academy from other facilities. Dedicated to providing quality care and tailored services, this center strives to assist clients on their path to recovery.

Lakeside Behavioral Health System

Situated in Memphis, TN, Lakeside Behavioral Health System delivers extensive rehabilitation services tailored for adults and seniors. This facility specializes in detoxification, treatment for substance use disorders, and managing co-occurring conditions, providing inpatient care around the clock. Lakeside employs various methods such as 12-step programming, anger management techniques, and brief intervention strategies to meet the unique needs of each individual. The center also offers specialized programs for active duty military members, as well as distinct services for adult men and women, ensuring it serves a wide range of clients. With a strong commitment to high-quality care and personalized treatment approaches, Lakeside Behavioral Health System stands out as a premier option for specialized addiction and mental health support in the area.

Lakeview Health Systems LLC

Lakeview Health Systems LLC, based in Jacksonville, FL, provides an extensive selection of addiction recovery services designed for both adults and young adults. The center features hospital inpatient detoxification and treatment, utilizing methods like 12-step facilitation and anger management. What sets this facility apart is its targeted programs for active military members, women, and those affected by intimate partner violence. Additionally, with options for transitional housing and treatment pathways specifically for each gender, Lakeview Health Systems LLC is dedicated to delivering personalized care that promotes effective and well-rounded recovery.

Lakewood Comprehensive Treatment Ctr

Lakewood Comprehensive Treatment Ctr, situated in Lakewood, WA, provides various outpatient services for substance use disorders. The facility offers treatments including methadone, buprenorphine, and naltrexone, utilizing effective methods such as brief interventions, cognitive behavioral therapy, and motivational incentives. It serves adult men and women, along with clients affected by intimate partner or domestic violence. With a commitment to cater to adults and young adults of all genders, this center emphasizes providing personalized care, making it an essential option for individuals seeking targeted addiction treatment solutions.

Lamprey Healthcare
Newmarket, NH

Lamprey Healthcare, situated in Newmarket, NH, is a full-service recovery facility dedicated to addressing substance use challenges in adults and young adults. They provide various levels of care, including outpatient services, medication-assisted treatment with methadone, buprenorphine, or naltrexone, and standard outpatient programs. Their therapeutic offerings encompass techniques like anger management, brief intervention, and cognitive behavioral therapy. Lamprey Healthcare serves adult men and women and supports individuals facing co-occurring mental health and substance use conditions. By emphasizing personalized attention and proven treatment methodologies, the center delivers effective recovery support for all patients.

Landmark Recovery
Indianapolis, IN

Landmark Recovery, located in Indianapolis, IN, provides a wide range of addiction recovery services for both adults and young adults. This center specializes in detoxification, treatment for substance use disorders, and offers dedicated support for those facing concurrent mental health conditions in adults or emotional issues in children. With a variety of treatment formats such as intensive outpatient, long-term residential, and outpatient care, Landmark Recovery customizes its services to meet the unique needs of each individual. The facility employs evidence-backed methods, including 12-step programs, cognitive behavioral therapy, and brief therapeutic interventions, to maintain a high standard of care. Additionally, there are specific programs aimed at active military members, as well as tailored options for adult men and women. Landmark Recovery is open to both male and female individuals in search of effective and personalized recovery solutions.

Landmark Recovery of Knoxville

Landmark Recovery of Knoxville, located in Seymour, TN, delivers extensive, research-backed therapeutic options for adults and young adults battling addiction and accompanying mental health challenges. The center features intensive outpatient, extended residential, and standard outpatient care, employing methods like 12-step guidance, cognitive behavioral therapy, and brief intervention strategies. Dedicated programs for active military personnel, adult men, and adult women are available, demonstrating Landmark Recovery of Knoxville's commitment to varied client requirements. Their customized treatment strategies and skilled professionals guarantee excellent care for all clients, establishing it as a premier destination for effective and individualized recovery assistance.

Landmark Recovery of Louisville

Landmark Recovery of Louisville in Louisville, KY, delivers extensive substance abuse rehabilitation for adults and young adults. Their offerings encompass detox services, drug and alcohol treatment, and tailored support for co-occurring mental health disorders. The center provides various treatment modalities, including intensive outpatient, residential stays, and flexible outpatient programs, to suit different requirements. Employing proven therapeutic strategies such as 12-step integration, cognitive behavioral therapy, and brief intervention techniques, Landmark Recovery ensures high-quality care. Additionally, they feature distinct programs designed for active military members, adult males, and adult females. A key focus at this facility is the development of personalized treatment strategies to aid every individual's path to recovery.

Lantana Recovery
Charleston, SC

Situated in Charleston, SC, Lantana Recovery provides targeted treatment for adults and young adults struggling with substance use and co-occurring mental health disorders. The center offers a range of services including intensive outpatient programs, outpatient treatments, and day treatment options, emphasizing 12-step support, anger management strategies, and cognitive behavioral therapy. Lantana Recovery adopts a personalized approach, ensuring high-quality care for both men and women. Clients can anticipate extensive support whether they opt for outpatient services or partial hospitalization, all within a compassionate and understanding setting. Opt for Lantana Recovery for evidence-based solutions and customized care on your path to recovery.

Las Vegas Comprehensive Treatment Ctr

Las Vegas Comprehensive Treatment Ctr, located in Las Vegas, NV, provides a wide range of outpatient treatment options for substance use disorders. The center specializes in administering methadone, buprenorphine, and naltrexone therapies. It offers personalized treatment plans that incorporate cognitive behavioral therapy, motivational interviewing, and strategies for preventing relapse. The facility serves all genders among adults and young adults, including those living with HIV/AIDS, as well as individuals dealing with co-occurring mental health issues and substance use challenges. Committed to delivering high-quality support and customized care, Las Vegas Comprehensive Treatment Ctr aims to assist individuals in their recovery process.

Las Vegas Paiute Tribe

Situated in Las Vegas, NV, the Las Vegas Paiute Tribe recovery facility extends outpatient support for substance use disorders, serving adults and seniors. This establishment delivers consistent outpatient care, employing proven methods like anger management, motivational interviewing, and cognitive behavioral therapy. Tailored programs are available for young people, adult males, and adult females, demonstrating a commitment to addressing varied requirements. The center ensures personalized support for all its male and female participants throughout their recovery process. The Las Vegas Paiute Tribe center is dedicated to providing excellent, all-encompassing rehabilitation services aimed at fostering lasting sobriety and emotional well-being.

Lamprey Healthcare

Situated in Raymond, NH, Lamprey Healthcare provides a wide array of substance abuse treatment options through its outpatient programs. This center is dedicated to supporting adult men, adult women, and individuals facing both mental health and substance use challenges. Emphasizing therapies such as anger management, brief interventions, and cognitive behavioral therapy, Lamprey Healthcare is designed for adults and young adults, regardless of gender. The facility offers tailored methadone, buprenorphine, or naltrexone programs, alongside standard outpatient services, ensuring that care is personalized to meet the unique needs of each client. Lamprey Healthcare is committed to offering high-quality, evidence-informed treatment to aid individuals in their recovery from addiction.

Lancaster Treatment Specialists

Lancaster Treatment Specialists, located in Lancaster, SC, provides a range of outpatient programs aimed at treating substance use disorders with a strong emphasis on personalized care. The center offers tailored treatment options, including methadone, buprenorphine, and naltrexone, specifically designed for adults and young adults. It features specialized programs catering to adult males, females, and pregnant/postpartum women, ensuring that the diverse needs of clients are met. Utilizing proven strategies such as 12-step facilitation, anger management, and brief interventions, Lancaster Treatment Specialists strive to foster enduring recovery. By incorporating gender-specific treatment pathways for both men and women, this center focuses on delivering individualized support and achieving positive results for those on their journey to recovery from addiction.

Lakeview Behavioral Health

Situated in Hibbing, MN, Lakeview Behavioral Health specializes in addressing substance abuse and mental health disorders concurrently for both adults and children. The facility offers various treatment options, including intensive outpatient, outpatient, and partial hospitalization, employing proven methods such as anger management, cognitive behavioral therapy, and motivational techniques. Lakeview Behavioral Health is equipped with customized programs for active military personnel, teenagers, and adult males, and it serves individuals of all genders, including seniors. Committed to delivering high-quality, personalized care, this center has earned a reputation as a reliable option for extensive rehabilitation services within the Hibbing community.

Lamprey Healthcare

Situated in Nashua, NH, Lamprey Healthcare specializes in providing targeted treatment for substance use to both adults and young adults. The center offers outpatient services such as methadone/buprenorphine or naltrexone therapy, along with standard outpatient programs and a range of strategies like anger management, brief interventions, and cognitive behavioral therapy. With an emphasis on delivering high-quality care, Lamprey Healthcare serves adult men and women, including those facing co-occurring mental health and substance use challenges. Its gender-specific initiatives and customized services foster a nurturing environment for individuals in pursuit of thorough and effective solutions for addiction recovery.

Lakeview Behavioral Health

Lakeview Behavioral Health, located in Grand Rapids, MN, delivers extensive rehabilitation services to both adults and young adults facing challenges related to substance use and concurrent mental health disorders. The center features various treatment options including intensive outpatient programs, outpatient day programs, and personalized outpatient services. With dedicated programs designed for active military personnel, as well as specific services for adult men and women, Lakeview Behavioral Health serves a wide range of individuals. The facility employs research-backed methods such as cognitive behavioral therapy and contingency management, focusing on effective strategies like anger management. Deeply committed to providing high-quality care, this center fosters a nurturing environment for those on their path to recovery.

Lakeview Center Inc
Pensacola, FL

Lakeview Center Inc, located in Pensacola, FL, provides focused treatment for substance abuse and co-occurring mental health issues for both adults and youth. The center offers various residential options, including long-term and short-term stays, and utilizes methods like 12-step facilitation, cognitive behavioral therapy, and the Matrix Model. Customized treatment programs are available for adults and adolescents, with gender-specific options for male and female clients. Lakeview Center Inc is recognized for its detailed treatment plans and high-quality care, ensuring that every participant receives individualized support as they work towards recovery.

Lassen Indian Health Center

The Lassen Indian Health Center, situated in Susanville, CA, provides outpatient services for addiction and withdrawal management, designed for adults and older adults. They accommodate male and female patients, utilizing techniques like anger management, cognitive behavioral therapy, and brief interventions. Emphasizing personalized care plans, the center delivers excellent support for individuals battling substance dependence. Offering outpatient methadone, buprenorphine, or naltrexone treatments, the center is a well-rounded option for those starting their path to sobriety.

Placeholder image

Landmark Recovery of Western Michigan, located in Battle Creek, MI, provides a variety of evidence-supported treatment options for adults and young adults facing addiction challenges. This facility emphasizes detoxification, treatment for substance use, and handling co-occurring disorders. Offering a spectrum of services that includes intensive outpatient, long-term residential, and outpatient programs, the center emphasizes a tailored approach through methods such as 12-step facilitation, cognitive behavioral therapy, and brief interventions. Additionally, there are specialized programs designed for active duty military and distinct groups of adult men and women, ensuring focused care. Catering to both genders, this center is dedicated to delivering effective and personalized rehabilitation solutions.

Placeholder image

Situated in Gainesville, GA, Lanier Treatment Center provides outpatient detox services and treatment for substance use issues for both adult males and females. The center emphasizes brief intervention techniques, cognitive behavioral therapy, and motivational interviewing. Lanier Treatment Center features specialized programs designed for individuals who have faced trauma, accommodating both adults and young adults. With a commitment to delivering high-quality care, the facility offers outpatient treatment options with methadone, buprenorphine, or naltrexone as needed. Their gender-specific programs are designed to offer personalized support for men and women pursuing complete and effective rehabilitation solutions.

Frequently Asked Questions

What is buprenorphine and how does it treat opioid addiction?
Buprenorphine is a partial opioid agonist medication approved by the FDA for treating opioid use disorder. It binds to the same receptors as heroin and fentanyl but produces a much weaker effect, reducing cravings and withdrawal symptoms without causing intense euphoria. Buprenorphine has a ceiling effect, meaning its opioid effects plateau at moderate doses, making it safer than methadone in terms of overdose risk.
What is the difference between Suboxone and Subutex?
Suboxone contains two active ingredients — buprenorphine and naloxone — while Subutex contains only buprenorphine without naloxone. The naloxone in Suboxone is included as an abuse deterrent; it remains inactive when taken sublingually as prescribed but triggers withdrawal if the medication is injected. Subutex is generally reserved for patients who cannot tolerate naloxone, such as pregnant women.
What is a Sublocade injection and how does it work?
Sublocade is a once-monthly injectable form of buprenorphine administered as a subcutaneous injection in the abdominal area. After injection, the medication forms a solid deposit under the skin that slowly releases buprenorphine over the course of a month. This eliminates daily dosing and removes the possibility of missed doses or medication diversion.
What are the common side effects of Suboxone?
Common Suboxone side effects include headache, nausea, constipation, insomnia, sweating, and mouth numbness or pain from sublingual administration. Some patients also experience dizziness, drowsiness, and blurred vision, particularly when starting treatment. Most side effects diminish within the first few weeks as the body adjusts. Patients should report difficulty breathing or signs of allergic reaction immediately.
What happens during Suboxone withdrawal?
Suboxone withdrawal occurs when a patient stops taking the medication abruptly after prolonged use, with symptoms including muscle aches, anxiety, insomnia, nausea, and irritability. A medically supervised taper is strongly recommended, typically reducing the dose by small increments over weeks or months. The risk of opioid relapse is significantly higher during unsupervised discontinuation.
How does Suboxone compare to methadone?
Suboxone and methadone are both effective for opioid use disorder but differ in key ways. Methadone is a full opioid agonist dispensed daily at licensed clinics, while Suboxone is a partial agonist that can be prescribed by qualified physicians and taken at home. Suboxone carries a lower overdose risk due to its ceiling effect and offers greater convenience, though methadone may be more appropriate for patients with severe, long-standing dependence.
How can I find a Suboxone clinic or doctor near me?
The most reliable way to find a Suboxone provider is through SAMHSA's online treatment locator at findtreatment.gov, which allows you to search by location and filter for buprenorphine providers. Many primary care offices, addiction treatment centers, and telehealth platforms now offer Suboxone prescriptions following the elimination of the federal X-waiver requirement in early 2023.
What is Zubsolv and how is it different from Suboxone?
Zubsolv is a brand-name buprenorphine and naloxone sublingual tablet that features a mint flavor and dissolves faster under the tongue than other options. Due to its higher bioavailability, Zubsolv uses different dosing strengths — a Zubsolv 5.7 mg/1.4 mg tablet is considered equivalent to a Suboxone 8 mg/2 mg dose. Patients switching between products should work closely with their prescriber for correct dose conversion.
Does Medicaid cover Suboxone treatment?
Yes — Medicaid covers buprenorphine (including Suboxone, Sublocade, Subutex, Zubsolv, and Brixadi) for opioid use disorder in all 50 states, as required by the SUPPORT Act of 2018. Medicaid is the largest single payer for MAT in the US. Coverage details vary by state — some require prior authorization or limit certain formulations. Many OBOT clinics accept Medicaid directly; telehealth Suboxone providers also bill Medicaid in most states. Bring your Medicaid card to your intake appointment.
Can I get Suboxone through telehealth?
Yes. After the MAT Act of 2023 permanently eliminated the X-waiver requirement, any licensed prescriber can prescribe Suboxone via telehealth in most states. The DEA also extended COVID-era telehealth flexibilities through at least 2025, allowing virtual Suboxone induction without a prior in-person visit. Several specialty platforms — Bicycle Health, Ophelia, Workit Health, Boulder Care — offer Medicaid-accepting telehealth Suboxone treatment. Telehealth has dramatically expanded access in rural and underserved areas with no nearby OBOT physicians.

About Buprenorphine (Suboxone)

Buprenorphine is classified as a partial opioid agonist, meaning it activates opioid receptors in the brain but to a much lesser degree than full agonists such as heroin, fentanyl, or oxycodone. This partial activation suppresses withdrawal symptoms and reduces cravings without producing dangerous respiratory depression or intense euphoria. Buprenorphine also has an unusually high binding affinity for the mu-opioid receptor, effectively blocking other opioids from attaching — providing a protective effect against relapse-related overdose.

How Buprenorphine Works

One of the defining features of buprenorphine is its ceiling effect — after a certain dose threshold, increasing the amount does not produce additional opioid effects. This dramatically reduces the risk of fatal overdose compared to methadone or illicit opioids. The ceiling effect, combined with its long duration of action (24 to 72 hours), makes buprenorphine one of the safest and most effective tools in medication-assisted treatment (MAT). Approved by the FDA in 2002, buprenorphine was a breakthrough because it could be prescribed in outpatient settings rather than requiring daily clinic visits.

Buprenorphine Brand Comparison: Suboxone, Subutex, Sublocade, Zubsolv, Brixadi

Buprenorphine is available under several FDA-approved brand names, each with distinct formulations, dosing schedules, and clinical use cases. The comparison below highlights the key differences:

BrandActive ingredientFormFrequencySettingFDA yearBest for
SuboxoneBuprenorphine + naloxoneSublingual film / tabletDailyOBOT, telehealth, retail pharmacy2002Most prescribed; naloxone deters injection misuse
SubutexBuprenorphine (alone)Sublingual tabletDailyOBOT2002Pregnancy; documented naloxone sensitivity
SublocadeBuprenorphine extended-releaseSubcutaneous injection (ATRIGEL depot)MonthlyClinic-administered2017No daily dosing; eliminates diversion risk
ZubsolvBuprenorphine + naloxoneSublingual tablet (higher bioavailability)DailyOBOT2013Faster dissolution; mint flavor; lower mg/dose
BrixadiBuprenorphine extended-releaseSubcutaneous injectionWeekly or monthlyClinic2023Newer alternative to Sublocade; weekly option for induction

All five medications are Schedule III controlled substances and equivalent in clinical efficacy at appropriate doses. The choice depends on adherence patterns, lifestyle, insurance coverage, and clinical context (e.g., pregnancy, prior injection use, daily-dosing burden). Many patients begin on sublingual Suboxone for stabilization and transition to monthly Sublocade or weekly Brixadi after sustained recovery.

Buprenorphine Side Effects

Common buprenorphine side effects include:

  • Headache and dizziness
  • Nausea and vomiting, especially during induction
  • Constipation and insomnia
  • Excessive sweating
  • Mouth numbness or oral discomfort from sublingual formulations

More serious side effects may include respiratory depression (particularly when combined with benzodiazepines or alcohol), liver problems, and allergic reactions. For most patients, side effects are mild and resolve within one to two weeks. The benefits in preventing relapse and overdose death significantly outweigh the risks.

Buprenorphine Dosage and Induction

Treatment begins with an induction phase where the patient must be in mild to moderate opioid withdrawal. Common induction doses range from 2 mg to 8 mg on the first day, with increases over the following days. Most patients stabilize on 8 mg to 24 mg per day, with 16 mg being the most commonly prescribed dose. Research suggests doses of 16 mg or higher are associated with better retention and outcomes. Dosage should always be adjusted under medical supervision.

Buprenorphine/Naloxone Combination

Many buprenorphine formulations include naloxone as an abuse deterrent. When taken sublingually as directed, naloxone has very low bioavailability and produces no clinical effect. However, if someone attempts to inject the medication, the naloxone component becomes fully active and triggers severe withdrawal. This design discourages injection misuse while having no impact on patients who take the medication correctly. The combination is the standard first-line formulation for opioid addiction treatment.

Suboxone: Sublingual Buprenorphine

Suboxone is the most recognized brand name for buprenorphine-naloxone and is most commonly dispensed as a sublingual film (Suboxone strips) that dissolves under the tongue. Suboxone has transformed opioid treatment by enabling millions of patients to receive effective pharmacotherapy in outpatient settings without the daily clinic visits required by methadone programs.

Suboxone Side Effects

Commonly reported Suboxone side effects include headache, nausea, tongue or mouth irritation, constipation, insomnia, sweating, and decreased libido. The sublingual film can cause irritation or small sores inside the mouth — rotating placement between under the tongue and against the cheek helps minimize this. Patients should not eat, drink, or smoke while the film is dissolving.

Suboxone Strips: Film vs. Tablet

Suboxone strips (sublingual film) have largely replaced the original tablet form. The film dissolves more quickly (two to four minutes), provides more consistent absorption, and is harder to divert due to individual foil packaging. Generic buprenorphine-naloxone tablets are often less expensive and may be preferred for cost reasons. Both are therapeutically equivalent when taken as prescribed.

Suboxone Treatment Programs

Comprehensive Suboxone treatment typically includes three phases:

  • Induction: Initial dosing under medical supervision, requiring the patient to be in early withdrawal
  • Stabilization: Dose adjustment until cravings and withdrawal are minimal, usually one to two months
  • Maintenance: Stable dosing for an extended period — often a year or longer — combined with counseling and behavioral therapy

Evidence consistently shows that longer treatment durations are associated with better outcomes. Most addiction medicine experts recommend a minimum of one to two years of maintenance therapy.

Find a Suboxone Clinic Near You — OBOT & Telehealth Options

Finding a Suboxone clinic has become significantly easier since the federal government eliminated the X-waiver requirement in January 2023, meaning any provider with a standard DEA license can now prescribe Suboxone. Patients can search SAMHSA's treatment locator at findtreatment.gov or use our directory to locate nearby facilities that offer buprenorphine-based treatment.

Suboxone Doctors Near Me

Beyond SAMHSA's locator, many state health departments maintain directories of addiction treatment providers. Telehealth has dramatically expanded access — several platforms now offer virtual Suboxone consultations, which is especially valuable for patients in rural areas. When selecting a provider, look for those offering comprehensive treatment including counseling, not just medication prescriptions.

Suboxone Withdrawal and Tapering

Suboxone withdrawal can include muscle aches, anxiety, insomnia, nausea, sweating, and intense opioid cravings. A gradual, medically supervised taper is recommended — typically reducing the dose by 10 to 25 percent every one to four weeks. Slower tapers over several months produce fewer symptoms and lower relapse rates. There is no medically mandated time limit for Suboxone treatment, and many patients benefit from indefinite maintenance.

Suboxone vs Methadone

Suboxone can be prescribed in office settings and taken at home, carries lower overdose risk due to its ceiling effect, and offers greater scheduling flexibility. Methadone is a full agonist that may be more effective for severe, long-standing dependence but must be dispensed at licensed clinics with daily visits. Neither is inherently superior — the best choice keeps the patient in treatment. Some patients may also benefit from naltrexone, a non-opioid alternative.

Sublocade: Monthly Buprenorphine Injection

Sublocade delivers buprenorphine as a once-monthly subcutaneous injection in the abdominal area using the ATRIGEL delivery system, which forms a solid biodegradable depot that slowly releases medication. Patients must first stabilize on sublingual buprenorphine (8 mg+ daily) for at least seven days. Treatment typically begins with two 300 mg injections, followed by maintenance on 300 mg or 100 mg. Sublocade eliminates concerns about daily adherence, missed doses, and medication diversion.

Sublocade Side Effects

The most common Sublocade side effects are injection-site reactions (pain, itching, redness, or a noticeable lump), nausea, constipation, headache, and fatigue. The injection-site lump is normal and gradually diminishes as medication is absorbed. Patients should avoid rubbing or massaging the site. Elevated liver enzymes may also occur but are usually mild and transient.

Subutex: Buprenorphine Without Naloxone

Subutex was the original brand-name buprenorphine product. While the brand has been discontinued, generic buprenorphine-only tablets remain available. Buprenorphine monotherapy is typically reserved for pregnant patients (to avoid naloxone exposure to the fetus), patients with documented naloxone sensitivity, or sometimes during the induction phase before transitioning to the combination product.

Subutex vs Suboxone

The primary difference is the absence of naloxone in Subutex. Because Subutex lacks the abuse-deterrent naloxone component, it may carry slightly higher diversion risk, and many insurance formularies prioritize the combination as the default. Current clinical guidelines favor buprenorphine-only formulations primarily for pregnancy and naloxone sensitivity.

Zubsolv: Alternative Buprenorphine Brand

Zubsolv is a buprenorphine-naloxone sublingual tablet featuring a mint flavor and faster dissolution (under two minutes). Due to enhanced bioavailability, Zubsolv uses different dose strengths — a 5.7 mg/1.4 mg tablet equals a Suboxone 8 mg/2 mg dose. Zubsolv is available in multiple strengths for flexible dosing during both induction and maintenance.

Buprenorphine resources:

Find Buprenorphine (Suboxone) by State

Browse buprenorphine (suboxone) programs in states with the most treatment options.

Explore Related Options

Related conditions, treatment approaches, and levels of care.

Medically Reviewed Updated August 2026

Reviewed by licensed addiction specialists. Information reflects current clinical guidance.

Sources:SAMHSA·NIDA·CDC

Need immediate help? Call SAMHSA: 1-800-662-4357 (24/7, free)