NWVCIL Logo
Medically Reviewed Content
Updated: August 2026
Sources: SAMHSA, NIDA

Suboxone Clinic Near You: Buprenorphine Treatment for Opioid Addiction

Find a Suboxone clinic near you. Buprenorphine — sold under brand names Suboxone, Sublocade, Subutex, Zubsolv, and Brixadi — is the most-prescribed MAT for opioid use disorder. It is a partial mu-opioid agonist with a ceiling effect that dramatically reduces overdose risk vs. methadone. After the MAT Act of 2023 eliminated the X-waiver requirement, any licensed prescriber can prescribe buprenorphine in office-based settings (OBOT), via telehealth, or at retail pharmacies. Buprenorphine is a Schedule III controlled substance and is covered by Medicaid in all 50 states.

Found 7,145 treatment centers offering buprenorphine (suboxone) across the United States.

Need Help Finding the Right Treatment Center?

Speak with a compassionate specialist now - 100% free & confidential

Call +1 (833) 244-3031
Available 24/7
All 50 States
Filters:

Showing 21 of 7145 results

Meridian Behavioral Health

Meridian Behavioral Health in Pine City, MN, delivers focused care for addiction within a live-in environment. This location features round-the-clock support via its short-term residential offerings. Emphasizing 12-step principles, emotional regulation techniques, and concise therapeutic methods, the center is designed for adult women impacted by domestic and relationship violence. Their services are structured for adults, older adults, and younger adults. Meridian Behavioral Health distinguishes itself through its complete assistance for its female clientele, guaranteeing individualized attention and successful paths to healing.

Meridian Behavioral Health

Meridian Behavioral Health, situated in Sauk Rapids, MN, delivers targeted substance abuse recovery programs for adult men experiencing dual mental health conditions. This facility offers supervised live-in treatment within a secure and nurturing setting, featuring concise residential options. Employing strategies such as 12-step encouragement, emotional regulation techniques, and concise counseling, this establishment serves adults, older individuals, and younger adults in need of thorough healing. Meridian Behavioral Health distinguishes itself through its dedication to tackling co-occurring disorders in a gender-focused atmosphere, emphasizing excellent care and personalized assistance.

Meridian Behavioral Healthcare Inc

Meridian Behavioral Healthcare Inc, located in Gainesville, FL, provides extensive detox services within a residential environment, including round-the-clock support. The center employs evidence-based methodologies, which encompass cognitive behavioral therapy, motivational interviewing, and relapse prevention strategies. This facility serves both adult men and women, as well as individuals who have undergone trauma. Meridian Behavioral Healthcare Inc also features specialized programs for young adults and emphasizes gender-sensitive treatment for both genders, offering customized care for a wide array of patients. Individuals can anticipate exceptional, personalized support as they progress on their path to recovery.

Meridian Behavioral Healthcare Inc

Meridian Behavioral Healthcare Inc located in Chiefland, FL, specializes in outpatient treatment for substance abuse as well as providing expert care for those facing both substance use and significant mental health issues. Their offerings encompass various programs such as anger management, short-term interventions, and cognitive behavioral therapy. This center caters to the unique needs of adult men and women, including those who have gone through traumatic experiences. Emphasizing support for both adults and adolescents, clients of all genders can access extensive assistance at this facility. Meridian Behavioral Healthcare Inc prioritizes high-quality care and personalized treatment strategies to aid clients in their recovery process.

Meridian Behavioral Healthcare Inc

Meridian Behavioral Healthcare Inc, situated in Gainesville, FL, delivers extensive recovery support. This facility offers intensive outpatient care, extended residential stays, and outpatient services for adults and young adults struggling with addiction and co-occurring mental health issues. Meridian Behavioral Healthcare Inc features distinct programs for active military, adult men, and women, employing proven methods like 12-step integration, anger management, and cognitive behavioral therapy for effective treatment. Serving both male and female individuals, the center crafts personalized plans to foster sustained healing.

Meridian Behavioral Healthcare Inc

Meridian Behavioral Healthcare Inc in Gainesville, FL, provides extensive outpatient support for individuals struggling with substance use disorders. The center excels in addressing complex cases, particularly those involving dual diagnoses of substance abuse and significant mental health challenges, with a dedicated focus on adults and young adults. Utilizing proven therapeutic methods such as cognitive behavioral therapy and anger management, Meridian Behavioral Healthcare Inc delivers personalized treatment plans. These include distinct programs designed for adult men, adult women, and individuals who have experienced trauma. The availability of outpatient medication-assisted treatment, including methadone, buprenorphine, or naltrexone, underscores Meridian Behavioral Healthcare Inc's commitment to delivering high-quality recovery services within a nurturing atmosphere.

Meridian Behavioral Healthcare Inc

Meridian Behavioral Healthcare Inc, situated in Gainesville, FL, delivers targeted therapeutic interventions for individuals grappling with substance abuse and related mental health challenges, catering to both younger and adult demographics. This establishment offers ambulatory care options, such as methadone and buprenorphine-assisted therapies. Employing scientifically validated methods, including cognitive behavioral therapy and motivational interviewing, the center prioritizes personalized support for adult women, individuals with HIV/AIDS, and those managing dual diagnoses. Meridian Behavioral Healthcare Inc also emphasizes anger management and offers specialized programs for young adults, ensuring holistic and impactful recovery support for all genders.

Merito House Addiction Treatment Ctr

Merito House Addiction Treatment Center located in San Bernardino, CA, provides a wide array of services for those seeking help with addiction. The center specializes in detox services, treatment for substance use disorders, transitional living arrangements, and sober housing for both adults and young adults. Offering programs that include intensive outpatient care, long-term residential stays, and outpatient treatment, Merito House addresses various specific recovery needs. Treatment methodologies employed range from 12-step support to anger management and brief interventions, ensuring that care plans are customized for each individual. Additionally, there are specialized programs tailored to adult men, women, and individuals facing both mental health and substance use challenges. Committed to delivering high-quality, individualized care, Merito House aims to assist people in their journey toward recovery.

Meta Addiction Treatment
North Reading, MA

Meta Addiction Treatment, situated in North Reading, MA, provides a complete spectrum of care for those seeking lasting sobriety. This institution offers various levels of care, including intensive outpatient, day treatment, and partial hospitalization programs, designed for adults and young adults grappling with addiction. Employing therapeutic modalities like 12-step integration, brief intervention, and cognitive behavioral therapy, the center crafts personalized recovery pathways. Recognizing diverse needs, Meta Addiction Treatment features distinct programs for active military members, adult men, and adult women, fostering a safe and understanding atmosphere. Their provision of transitional housing, halfway house accommodations, and sober living environments significantly bolsters their commitment to comprehensive client support.

Meta House Inc
Milwaukee, WI

Situated in Milwaukee, WI, Meta House Inc delivers an extensive array of long-term, short-term, and around-the-clock residential programs aimed at adult women in need of substance use recovery. This center focuses on individuals facing both substance use and mental health challenges. It offers dedicated services for those who have undergone trauma, featuring customized programs for various age groups, including adults, seniors, and young adults. Meta House Inc employs proven strategies such as 12-step support, anger management, and brief interventions to guarantee optimal care for every client. For those in search of a nurturing and women-centered atmosphere for overcoming addiction, this facility provides a caring and effective healing journey.

Meridian Behavioral Health

Meridian Behavioral Health in Stillwater, MN, provides targeted support for adult men grappling with both addiction and concurrent mental health challenges within a residential environment. This facility offers continuous around-the-clock care, emphasizing techniques such as anger management, brief intervention strategies, and cognitive behavioral therapy. Customized treatment plans are available for adult individuals, seniors, and younger adults, ensuring personalized recovery journeys. Meridian Behavioral Health distinguishes itself through its holistic methodology, simultaneously tackling substance abuse and significant mental health conditions. Dedicated to high-quality services and bespoke treatment strategies, this center fosters a nurturing atmosphere for individuals pursuing short-term residential recovery.

Meta Addiction Treatment

Meta Addiction Treatment, situated in Haverhill, MA, provides thorough care for adults and younger adults struggling with substance use. They offer structured programs including intensive outpatient, standard outpatient, and partial hospitalization (day treatment). Employing proven methods such as 12-step facilitation, brief intervention, and cognitive behavioral therapy, the center personalizes recovery plans. Meta Addiction Treatment also features dedicated programs for active-duty military personnel, adult men, and adult women, demonstrating their commitment to serving a broad spectrum of individuals. Their services are available to both male and female clients, ensuring comprehensive support for those on their journey to recovery.

Meridian Behavioral Healthcare Inc

Meridian Behavioral Healthcare Inc, located in Lake City, FL, provides an extensive array of substance abuse treatment services for both adults and children facing concurrent mental health challenges. The center offers diverse treatment alternatives, including intensive outpatient services, long-term residential care, and standard outpatient programs, all tailored to meet individual needs. Therapies such as cognitive behavioral therapy and anger management form the foundation of their approach. The facility features specialized programs for youth, individuals living with HIV or AIDS, and those experiencing both mental health and substance use issues. Catering to a diverse population of male and female clients across various age brackets, Meridian Behavioral Healthcare Inc stands out as a reliable option for personalized addiction recovery services.

Meridian Healthcare
Youngstown, OH

Meridian Healthcare, located in Youngstown, OH, provides an extensive array of services for individuals facing substance use issues and co-occurring mental health disorders, catering to both adults and children. The center offers various treatment options, including intensive outpatient, outpatient, and medications such as methadone, buprenorphine, or naltrexone. Emphasizing methods like 12-step facilitation, anger management, and brief interventions, the facility supports a diverse clientele, including active duty military members, adolescents, and adult males. Meridian Healthcare is dedicated to delivering quality care and assistance to individuals from all gender identities who are on their journey to recovery from substance use and mental health difficulties.

Meridian Behavioral Health

Meridian Behavioral Health in Saint Paul, MN, provides extensive support for individuals struggling with substance use disorders, utilizing diverse program structures like intensive outpatient, standard outpatient, and ongoing outpatient care. Employing proven methods such as 12-step facilitation, brief intervention, and cognitive behavioral therapy, they deliver customized recovery plans. This center features dedicated services for active military personnel, adult men, adult women, and supports both adult and young adult populations of all genders. Known for its commitment to high-quality, individualized treatment, Meridian Behavioral Health stands as a reliable resource for effective and nurturing addiction recovery services in the Saint Paul vicinity.

Merrimack River Medical Services

Merrimack River Medical Services in Hudson, NH, specializes in outpatient substance use disorder services. They provide medication-assisted treatment using methadone, buprenorphine, or naltrexone. Their therapeutic approach incorporates 12-step facilitation, anger management techniques, and brief intervention strategies. The center offers distinct programs for adult men and women, including those affected by intimate partner or domestic violence. Catering to both adults and young adults, they ensure gender-specific counseling for both male and female patients. Merrimack River Medical Services is dedicated to delivering effective, personalized care to support individuals on their journey to recovery.

Meridian Behavioral Healthcare

Meridian Behavioral Healthcare in Palatka, FL, delivers thorough outpatient services for individuals of all ages battling addiction and coinciding mental health conditions. Their tailored programs are designed for adult men, adult women, and those who have undergone trauma. Employing strategies such as anger management, cognitive behavioral therapy, and brief interventions, this center offers individualized support for those pursuing recovery. Dedicated to excellence and customized care, Meridian Behavioral Healthcare supports both male and female patients of varying ages, fostering a nurturing atmosphere for wellness and personal development.

Merrimack River Medical Services

Merrimack River Medical Services, located in Lewiston, ME, specializes in offering extensive treatment for substance use disorders through personalized outpatient programs. The facility administers methadone/buprenorphine or naltrexone therapy, alongside standard outpatient treatment options, employing proven methods such as cognitive behavioral therapy, motivational interviewing, and contingency management. Catering to both men and women, as well as individuals with dual diagnoses of mental health and substance abuse issues, this center serves adults and young adults across various demographics. Committed to delivering high-quality care and customized treatment strategies, Merrimack River Medical Services aims to assist individuals in their recovery journey.

Placeholder image

Meridian Behavioral Healthcare Inc, situated in Ocala, FL, delivers complete addiction treatment and tailored support for those facing dual diagnoses of substance abuse and significant mental health challenges. The center offers a range of outpatient therapies, including medication-assisted treatment with methadone, buprenorphine, or naltrexone, alongside programs for anger management, cognitive behavioral therapy, and trauma-informed care, serving adults, children, and adolescents. By emphasizing personalized treatment plans and research-backed methods, Meridian Behavioral Healthcare Inc is committed to offering high-quality services aimed at fostering enduring recovery and enhanced psychological well-being for its patients.

Placeholder image

Meridian Healthcare in Warren, OH, provides extensive care for adults struggling with substance use and co-occurring mental health challenges, as well as for children facing emotional disturbances. The facility offers robust intensive outpatient and outpatient services, incorporating medication-assisted treatment like methadone, buprenorphine, and naltrexone. Meridian Healthcare is equipped to serve various populations, including active duty military personnel, adolescents, and adult men, through specialized programs. They employ therapeutic strategies such as 12-step facilitation, anger management techniques, and brief interventions, ensuring that each individual receives tailored support. This center is committed to offering top-tier, scientifically supported rehabilitation for both male and female clients of all ages.

Placeholder image

Mesa County Criminal Justice Servs, situated in Grand Junction, CO, delivers a thorough suite of recovery support. This establishment features robust outpatient treatment, extended residential care, and standard outpatient services designed for adults and adolescents facing challenges with substance abuse and coexisting mental health conditions. The center emphasizes personalized support through unique programs for individuals affected by intimate partner violence and domestic abuse. Employing therapeutic methods like anger management, cognitive behavioral therapy, and motivational reinforcement, Mesa County Criminal Justice Servs assists adult men and women, providing safe housing during their transition and options for sober living. Dedicated to excellence in care, this organization is focused on empowering individuals toward lasting wellness.

Frequently Asked Questions

What is buprenorphine and how does it treat opioid addiction?
Buprenorphine is a partial opioid agonist medication approved by the FDA for treating opioid use disorder. It binds to the same receptors as heroin and fentanyl but produces a much weaker effect, reducing cravings and withdrawal symptoms without causing intense euphoria. Buprenorphine has a ceiling effect, meaning its opioid effects plateau at moderate doses, making it safer than methadone in terms of overdose risk.
What is the difference between Suboxone and Subutex?
Suboxone contains two active ingredients — buprenorphine and naloxone — while Subutex contains only buprenorphine without naloxone. The naloxone in Suboxone is included as an abuse deterrent; it remains inactive when taken sublingually as prescribed but triggers withdrawal if the medication is injected. Subutex is generally reserved for patients who cannot tolerate naloxone, such as pregnant women.
What is a Sublocade injection and how does it work?
Sublocade is a once-monthly injectable form of buprenorphine administered as a subcutaneous injection in the abdominal area. After injection, the medication forms a solid deposit under the skin that slowly releases buprenorphine over the course of a month. This eliminates daily dosing and removes the possibility of missed doses or medication diversion.
What are the common side effects of Suboxone?
Common Suboxone side effects include headache, nausea, constipation, insomnia, sweating, and mouth numbness or pain from sublingual administration. Some patients also experience dizziness, drowsiness, and blurred vision, particularly when starting treatment. Most side effects diminish within the first few weeks as the body adjusts. Patients should report difficulty breathing or signs of allergic reaction immediately.
What happens during Suboxone withdrawal?
Suboxone withdrawal occurs when a patient stops taking the medication abruptly after prolonged use, with symptoms including muscle aches, anxiety, insomnia, nausea, and irritability. A medically supervised taper is strongly recommended, typically reducing the dose by small increments over weeks or months. The risk of opioid relapse is significantly higher during unsupervised discontinuation.
How does Suboxone compare to methadone?
Suboxone and methadone are both effective for opioid use disorder but differ in key ways. Methadone is a full opioid agonist dispensed daily at licensed clinics, while Suboxone is a partial agonist that can be prescribed by qualified physicians and taken at home. Suboxone carries a lower overdose risk due to its ceiling effect and offers greater convenience, though methadone may be more appropriate for patients with severe, long-standing dependence.
How can I find a Suboxone clinic or doctor near me?
The most reliable way to find a Suboxone provider is through SAMHSA's online treatment locator at findtreatment.gov, which allows you to search by location and filter for buprenorphine providers. Many primary care offices, addiction treatment centers, and telehealth platforms now offer Suboxone prescriptions following the elimination of the federal X-waiver requirement in early 2023.
What is Zubsolv and how is it different from Suboxone?
Zubsolv is a brand-name buprenorphine and naloxone sublingual tablet that features a mint flavor and dissolves faster under the tongue than other options. Due to its higher bioavailability, Zubsolv uses different dosing strengths — a Zubsolv 5.7 mg/1.4 mg tablet is considered equivalent to a Suboxone 8 mg/2 mg dose. Patients switching between products should work closely with their prescriber for correct dose conversion.
Does Medicaid cover Suboxone treatment?
Yes — Medicaid covers buprenorphine (including Suboxone, Sublocade, Subutex, Zubsolv, and Brixadi) for opioid use disorder in all 50 states, as required by the SUPPORT Act of 2018. Medicaid is the largest single payer for MAT in the US. Coverage details vary by state — some require prior authorization or limit certain formulations. Many OBOT clinics accept Medicaid directly; telehealth Suboxone providers also bill Medicaid in most states. Bring your Medicaid card to your intake appointment.
Can I get Suboxone through telehealth?
Yes. After the MAT Act of 2023 permanently eliminated the X-waiver requirement, any licensed prescriber can prescribe Suboxone via telehealth in most states. The DEA also extended COVID-era telehealth flexibilities through at least 2025, allowing virtual Suboxone induction without a prior in-person visit. Several specialty platforms — Bicycle Health, Ophelia, Workit Health, Boulder Care — offer Medicaid-accepting telehealth Suboxone treatment. Telehealth has dramatically expanded access in rural and underserved areas with no nearby OBOT physicians.

About Buprenorphine (Suboxone)

Buprenorphine is classified as a partial opioid agonist, meaning it activates opioid receptors in the brain but to a much lesser degree than full agonists such as heroin, fentanyl, or oxycodone. This partial activation suppresses withdrawal symptoms and reduces cravings without producing dangerous respiratory depression or intense euphoria. Buprenorphine also has an unusually high binding affinity for the mu-opioid receptor, effectively blocking other opioids from attaching — providing a protective effect against relapse-related overdose.

How Buprenorphine Works

One of the defining features of buprenorphine is its ceiling effect — after a certain dose threshold, increasing the amount does not produce additional opioid effects. This dramatically reduces the risk of fatal overdose compared to methadone or illicit opioids. The ceiling effect, combined with its long duration of action (24 to 72 hours), makes buprenorphine one of the safest and most effective tools in medication-assisted treatment (MAT). Approved by the FDA in 2002, buprenorphine was a breakthrough because it could be prescribed in outpatient settings rather than requiring daily clinic visits.

Buprenorphine Brand Comparison: Suboxone, Subutex, Sublocade, Zubsolv, Brixadi

Buprenorphine is available under several FDA-approved brand names, each with distinct formulations, dosing schedules, and clinical use cases. The comparison below highlights the key differences:

BrandActive ingredientFormFrequencySettingFDA yearBest for
SuboxoneBuprenorphine + naloxoneSublingual film / tabletDailyOBOT, telehealth, retail pharmacy2002Most prescribed; naloxone deters injection misuse
SubutexBuprenorphine (alone)Sublingual tabletDailyOBOT2002Pregnancy; documented naloxone sensitivity
SublocadeBuprenorphine extended-releaseSubcutaneous injection (ATRIGEL depot)MonthlyClinic-administered2017No daily dosing; eliminates diversion risk
ZubsolvBuprenorphine + naloxoneSublingual tablet (higher bioavailability)DailyOBOT2013Faster dissolution; mint flavor; lower mg/dose
BrixadiBuprenorphine extended-releaseSubcutaneous injectionWeekly or monthlyClinic2023Newer alternative to Sublocade; weekly option for induction

All five medications are Schedule III controlled substances and equivalent in clinical efficacy at appropriate doses. The choice depends on adherence patterns, lifestyle, insurance coverage, and clinical context (e.g., pregnancy, prior injection use, daily-dosing burden). Many patients begin on sublingual Suboxone for stabilization and transition to monthly Sublocade or weekly Brixadi after sustained recovery.

Buprenorphine Side Effects

Common buprenorphine side effects include:

  • Headache and dizziness
  • Nausea and vomiting, especially during induction
  • Constipation and insomnia
  • Excessive sweating
  • Mouth numbness or oral discomfort from sublingual formulations

More serious side effects may include respiratory depression (particularly when combined with benzodiazepines or alcohol), liver problems, and allergic reactions. For most patients, side effects are mild and resolve within one to two weeks. The benefits in preventing relapse and overdose death significantly outweigh the risks.

Buprenorphine Dosage and Induction

Treatment begins with an induction phase where the patient must be in mild to moderate opioid withdrawal. Common induction doses range from 2 mg to 8 mg on the first day, with increases over the following days. Most patients stabilize on 8 mg to 24 mg per day, with 16 mg being the most commonly prescribed dose. Research suggests doses of 16 mg or higher are associated with better retention and outcomes. Dosage should always be adjusted under medical supervision.

Buprenorphine/Naloxone Combination

Many buprenorphine formulations include naloxone as an abuse deterrent. When taken sublingually as directed, naloxone has very low bioavailability and produces no clinical effect. However, if someone attempts to inject the medication, the naloxone component becomes fully active and triggers severe withdrawal. This design discourages injection misuse while having no impact on patients who take the medication correctly. The combination is the standard first-line formulation for opioid addiction treatment.

Suboxone: Sublingual Buprenorphine

Suboxone is the most recognized brand name for buprenorphine-naloxone and is most commonly dispensed as a sublingual film (Suboxone strips) that dissolves under the tongue. Suboxone has transformed opioid treatment by enabling millions of patients to receive effective pharmacotherapy in outpatient settings without the daily clinic visits required by methadone programs.

Suboxone Side Effects

Commonly reported Suboxone side effects include headache, nausea, tongue or mouth irritation, constipation, insomnia, sweating, and decreased libido. The sublingual film can cause irritation or small sores inside the mouth — rotating placement between under the tongue and against the cheek helps minimize this. Patients should not eat, drink, or smoke while the film is dissolving.

Suboxone Strips: Film vs. Tablet

Suboxone strips (sublingual film) have largely replaced the original tablet form. The film dissolves more quickly (two to four minutes), provides more consistent absorption, and is harder to divert due to individual foil packaging. Generic buprenorphine-naloxone tablets are often less expensive and may be preferred for cost reasons. Both are therapeutically equivalent when taken as prescribed.

Suboxone Treatment Programs

Comprehensive Suboxone treatment typically includes three phases:

  • Induction: Initial dosing under medical supervision, requiring the patient to be in early withdrawal
  • Stabilization: Dose adjustment until cravings and withdrawal are minimal, usually one to two months
  • Maintenance: Stable dosing for an extended period — often a year or longer — combined with counseling and behavioral therapy

Evidence consistently shows that longer treatment durations are associated with better outcomes. Most addiction medicine experts recommend a minimum of one to two years of maintenance therapy.

Find a Suboxone Clinic Near You — OBOT & Telehealth Options

Finding a Suboxone clinic has become significantly easier since the federal government eliminated the X-waiver requirement in January 2023, meaning any provider with a standard DEA license can now prescribe Suboxone. Patients can search SAMHSA's treatment locator at findtreatment.gov or use our directory to locate nearby facilities that offer buprenorphine-based treatment.

Suboxone Doctors Near Me

Beyond SAMHSA's locator, many state health departments maintain directories of addiction treatment providers. Telehealth has dramatically expanded access — several platforms now offer virtual Suboxone consultations, which is especially valuable for patients in rural areas. When selecting a provider, look for those offering comprehensive treatment including counseling, not just medication prescriptions.

Suboxone Withdrawal and Tapering

Suboxone withdrawal can include muscle aches, anxiety, insomnia, nausea, sweating, and intense opioid cravings. A gradual, medically supervised taper is recommended — typically reducing the dose by 10 to 25 percent every one to four weeks. Slower tapers over several months produce fewer symptoms and lower relapse rates. There is no medically mandated time limit for Suboxone treatment, and many patients benefit from indefinite maintenance.

Suboxone vs Methadone

Suboxone can be prescribed in office settings and taken at home, carries lower overdose risk due to its ceiling effect, and offers greater scheduling flexibility. Methadone is a full agonist that may be more effective for severe, long-standing dependence but must be dispensed at licensed clinics with daily visits. Neither is inherently superior — the best choice keeps the patient in treatment. Some patients may also benefit from naltrexone, a non-opioid alternative.

Sublocade: Monthly Buprenorphine Injection

Sublocade delivers buprenorphine as a once-monthly subcutaneous injection in the abdominal area using the ATRIGEL delivery system, which forms a solid biodegradable depot that slowly releases medication. Patients must first stabilize on sublingual buprenorphine (8 mg+ daily) for at least seven days. Treatment typically begins with two 300 mg injections, followed by maintenance on 300 mg or 100 mg. Sublocade eliminates concerns about daily adherence, missed doses, and medication diversion.

Sublocade Side Effects

The most common Sublocade side effects are injection-site reactions (pain, itching, redness, or a noticeable lump), nausea, constipation, headache, and fatigue. The injection-site lump is normal and gradually diminishes as medication is absorbed. Patients should avoid rubbing or massaging the site. Elevated liver enzymes may also occur but are usually mild and transient.

Subutex: Buprenorphine Without Naloxone

Subutex was the original brand-name buprenorphine product. While the brand has been discontinued, generic buprenorphine-only tablets remain available. Buprenorphine monotherapy is typically reserved for pregnant patients (to avoid naloxone exposure to the fetus), patients with documented naloxone sensitivity, or sometimes during the induction phase before transitioning to the combination product.

Subutex vs Suboxone

The primary difference is the absence of naloxone in Subutex. Because Subutex lacks the abuse-deterrent naloxone component, it may carry slightly higher diversion risk, and many insurance formularies prioritize the combination as the default. Current clinical guidelines favor buprenorphine-only formulations primarily for pregnancy and naloxone sensitivity.

Zubsolv: Alternative Buprenorphine Brand

Zubsolv is a buprenorphine-naloxone sublingual tablet featuring a mint flavor and faster dissolution (under two minutes). Due to enhanced bioavailability, Zubsolv uses different dose strengths — a 5.7 mg/1.4 mg tablet equals a Suboxone 8 mg/2 mg dose. Zubsolv is available in multiple strengths for flexible dosing during both induction and maintenance.

Buprenorphine resources:

Find Buprenorphine (Suboxone) by State

Browse buprenorphine (suboxone) programs in states with the most treatment options.

Explore Related Options

Related conditions, treatment approaches, and levels of care.

Medically Reviewed Updated August 2026

Reviewed by licensed addiction specialists. Information reflects current clinical guidance.

Sources:SAMHSA·NIDA·CDC

Need immediate help? Call SAMHSA: 1-800-662-4357 (24/7, free)