NWVCIL Logo
Medically Reviewed Content
Updated: August 2026
Sources: SAMHSA, NIDA

Suboxone Clinic Near You: Buprenorphine Treatment for Opioid Addiction

Find a Suboxone clinic near you. Buprenorphine — sold under brand names Suboxone, Sublocade, Subutex, Zubsolv, and Brixadi — is the most-prescribed MAT for opioid use disorder. It is a partial mu-opioid agonist with a ceiling effect that dramatically reduces overdose risk vs. methadone. After the MAT Act of 2023 eliminated the X-waiver requirement, any licensed prescriber can prescribe buprenorphine in office-based settings (OBOT), via telehealth, or at retail pharmacies. Buprenorphine is a Schedule III controlled substance and is covered by Medicaid in all 50 states.

Found 7,145 treatment centers offering buprenorphine (suboxone) across the United States.

Need Help Finding the Right Treatment Center?

Speak with a compassionate specialist now - 100% free & confidential

Call +1 (833) 244-3031
Available 24/7
All 50 States
Filters:

Showing 21 of 7145 results

National Addiction Specialists

Situated in Brentwood, TN, National Addiction Specialists delivers a wide range of addiction treatment options. The center offers detox services along with outpatient substance use programs, featuring treatments with methadone/buprenorphine or naltrexone. Utilizing proven techniques, the facility incorporates methods such as brief interventions, cognitive-behavioral therapy, and motivational incentives. National Addiction Specialists serves both men and women, providing customized programs to meet the distinct needs of each gender. Catering to adults and young adults, the center emphasizes individualized care, dedicated to assisting individuals throughout their recovery process.

National Capital Trt and Recovery

Situated in Arlington, VA, National Capital Trt and Recovery delivers an extensive array of long-term residential treatment services designed for adult men facing challenges with substance abuse and concurrent mental health conditions. The center emphasizes personalized care using methods like 12-step support, anger management techniques, and short intervention strategies. Tailored programs are offered for individuals who have dealt with traumatic experiences, providing focused assistance for those requiring guidance. Committed to delivering exceptional care, this facility serves adults, seniors, and young adults in need of residential detoxification and round-the-clock support.

Native American Recovery Center

Situated in Phoenix, AZ, the Native American Recovery Center delivers exceptional treatment for substance use challenges for both adults and young adults. The facility is particularly adept at addressing co-occurring disorders that include substance use and significant mental health conditions, offering a variety of programs such as long-term residential, short-term residential, and 24-hour residential care. By employing methods like 12-step facilitation, anger management, and brief intervention, the center customizes its treatment plans to meet the unique needs of each individual. Committed to a personalized approach, the center ensures distinctive care for men and women alike. Those in search of a well-rounded and culturally attuned recovery journey will find the Native American Recovery Center to be a standout option, recognized for its high-quality services and varied program selection.

NATIVE Project
Spokane, WA

The NATIVE Project, situated in Spokane, WA, specializes in substance use rehabilitation for adults facing significant mental health challenges alongside children dealing with emotional disturbances. The center offers both intensive outpatient and outpatient programs, featuring a variety of services such as 12-step support, anger management classes, and short-term interventions. Programs are specifically designed for adolescents, as well as adult men and women, ensuring that care is customized to the individual's needs. NATIVE Project caters to a diverse clientele, including adults, adolescents, and young adults, focusing on high-standard, evidence-informed treatment that respects cultural backgrounds. If you are looking for a holistic approach to addiction recovery with an emphasis on mental health care, this center provides extensive resources to aid your healing process.

Natural State Recovery Centers
North Little Rock, AR

Natural State Recovery Centers in North Little Rock, AR, delivers a full spectrum of substance abuse treatment. Their offerings include inpatient detox and a variety of residential care options, providing continuous support or shorter program durations. Emphasizing personalized recovery, they employ methods like 12-step integration, emotional regulation training, and concise counseling. Natural State Recovery Centers serves individuals of all ages and genders. Their specialized interventions and custom treatment strategies position them as a strong option for individuals desiring effective and customized recovery.

Near North Health

Located in Chicago, IL, Near North Health specializes in outpatient programs for individuals facing substance use disorders alongside significant mental health challenges or emotional difficulties. Their offerings encompass various treatments, including outpatient care with methadone, buprenorphine, or naltrexone, as well as standard outpatient services. The center employs diverse therapeutic strategies, featuring anger management, brief intervention, and cognitive behavioral therapy. Moreover, Near North Health has tailored initiatives for adult men, adult women, and those affected by domestic or intimate partner violence. This facility assures comprehensive support for both male and female clients in their journey toward recovery from addiction and mental health issues.

NE Arkansas Community MH Center

NE Arkansas Community MH Center located in Marianna, AR, focuses on delivering tailored outpatient services for adults dealing with substance use issues and co-occurring serious mental health conditions, as well as for children coping with significant emotional disturbances. The center features ongoing outpatient initiatives such as brief interventions, cognitive behavioral therapy, and the Matrix Model. Adopting a personalized strategy, the facility serves adults and seniors of various genders. With a committed team of professionals, this center provides extensive care and support for individuals striving for recovery from addiction and mental health difficulties.

Nebraska Urban Indian Health Coalition

The Nebraska Urban Indian Health Coalition, based in Omaha, NE, delivers extensive services for substance use disorders alongside tailored support for those facing dual mental health issues. Offering a variety of treatment formats, including long-term residential care and outpatient services with medication-assisted therapy, this center emphasizes 12-step programs, anger management techniques, and short-term interventions. It serves both adult men and women, as well as individuals who have undergone traumatic experiences. The facility is committed to providing personalized care and utilizes proven methods to foster successful recovery paths for adults and young adults of all backgrounds.

Neil Dobbins Center
Asheville, NC

Situated in Asheville, NC, the Neil Dobbins Center presents an extensive array of treatment alternatives for those facing challenges with substance abuse and related mental health issues. This facility encompasses inpatient detoxification and treatment services available around the clock for adults and young adults. Emphasizing personalized care, the center incorporates various methods, including 12-step programs, anger management techniques, and brief interventions to facilitate recovery. Notably, the center offers specialized programs designed to address the unique requirements of each individual. The Neil Dobbins Center is open to both men and women in search of top-notch, customized rehabilitation solutions.

Navos
Seattle, WA

Navos, situated in Seattle, WA, stands as a leading treatment facility providing robust outpatient services for individuals of all ages struggling with addiction and comorbid mental health challenges. The center employs scientifically validated therapeutic modalities like cognitive behavioral therapy and motivational interviewing, complemented by programs designed to foster long-term sobriety. Navos extends its services to a wide range of individuals, including those in the armed forces, adult men, and women. Featuring distinct programs for adults and adolescents of all genders, this institution prioritizes personalized care and recovery pathways. Opt for Navos for thorough, excellent treatment tailored to the specific requirements of every person seeking help.

National Capital Trt and Recovery

Situated in Arlington, VA, National Capital Trt and Recovery delivers focused outpatient programs for substance use rehabilitation, catering to both adults and young adults. The center employs proven techniques including brief intervention, cognitive behavioral therapy, and contingency management to create personalized care plans for each individual. With an inclusive approach for both male and female clients, the facility promotes a holistic treatment experience. National Capital Trt and Recovery distinguishes itself through its commitment to tailored treatment strategies and a nurturing atmosphere, making it a leading option for those in search of effective addiction recovery services in the region.

NE Arkansas Community MH Center

The NE Arkansas Community MH Center, located in Paragould, AR, specializes in providing outpatient treatment for substance use issues and has expertise in addressing co-occurring mental health disorders in adults, along with emotional challenges in children. The center features a variety of services, including outpatient day therapy, partial hospitalization, and traditional outpatient care. Employing methodologies like brief intervention, cognitive behavioral therapy, and the Matrix Model, the facility emphasizes personalized care for adults and seniors, regardless of gender. Dedicated to delivering exceptional and customized treatment plans, the NE Arkansas Community MH Center is distinguished by its extensive programs aimed at fostering recovery and overall wellness.

Near North Health Service Corporation

Near North Health Service Corporation, located in Chicago, IL, provides outpatient treatment for substance use, with a focus on individuals dealing with both substance use disorders and significant mental health issues, particularly in adults, as well as emotional challenges in children. Their offerings encompass programs like anger management, brief interventions, and cognitive behavioral therapy. This center caters specifically to adult men and women, including those who have suffered from domestic violence or intimate partner abuse. Emphasizing care for adults and young adults of all genders, Near North Health Service Corporation ensures effective treatment through outpatient services using methadone, buprenorphine, or naltrexone, alongside regular outpatient care.

National Capital Trt and Recovery

National Capital Trt and Recovery, located in Arlington, VA, delivers an extensive array of services for those in need of addiction rehabilitation. This center specializes in detoxification, treatment for substance use disorders, and tailored support for adults with co-occurring mental health concerns or children experiencing emotional challenges. Offering various treatment modalities, including intensive outpatient and day treatment programs, it serves both adult and adolescent populations. The center employs diverse methodologies such as 12-step support, anger management techniques, and brief therapeutic interventions to guarantee customized and impactful care. Additionally, National Capital Trt and Recovery features distinct programs specifically designed for young individuals and provides gender-sensitive treatment options for both men and women, focusing on a comprehensive and personalized recovery journey.

NCH Patient Care Center Colebrook

NCH Patient Care Center Colebrook, situated in Colebrook, NH, delivers expert outpatient services for adults grappling with substance use disorders and co-occurring mental health conditions, alongside specialized support for children experiencing emotional disturbances. Their treatment options encompass outpatient medication-assisted treatment (methadone/buprenorphine or naltrexone) and standard outpatient therapy. The center champions personalized care, designing bespoke programs for adults and young individuals across all gender identities. Employing evidence-based strategies such as 12-step facilitation, anger management, and brief intervention techniques, NCH Patient Care Center Colebrook is dedicated to providing thorough and tailored recovery support. They are committed to delivering high-quality, individualized treatment experiences.

NE Arkansas Community MH Center

NE Arkansas Community MH Center, located in Walnut Ridge, AR, provides outpatient services for individuals struggling with substance use disorders. They also specialize in addressing co-occurring conditions, offering support for adults with serious mental health illnesses and children experiencing serious emotional disturbances. Employing techniques such as brief intervention, cognitive behavioral therapy, and motivational interviewing, the center develops personalized treatment plans for adults and seniors across all genders. Their commitment to an individualized approach guarantees high-quality care customized to each person's specific requirements. For those looking for scientifically proven treatments within a supportive setting, this center could be an excellent resource for embarking on a path to recovery.

NE Arkansas Community MH Center

The NE Arkansas Community MH Center, situated in Helena, AR, delivers targeted substance use interventions. Their expertise lies in addressing the complex interplay of addiction and co-occurring mental health challenges, serving adults with serious mental health conditions and children with emotional disturbances. Through an outpatient framework, the center employs proven therapeutic modalities, including brief intervention, cognitive behavioral therapy, and the Matrix Model. Prioritizing a personalized approach, the NE Arkansas Community MH Center is equipped to assist adults and seniors, irrespective of gender, on their path to sustained recovery with dedicated and tailored care.

Placeholder image
Mansfield Center, CT

Natchaug Hospital Inc, situated in Mansfield Center, CT, offers thorough addiction recovery services for adults and adolescents dealing with co-occurring severe mental health disorders. This center provides intensive outpatient, outpatient, and day treatment programs, with expertise in anger management, brief intervention, and cognitive behavioral therapy. Natchaug Hospital Inc designs personalized treatment plans for active duty military, adult men, and women, guaranteeing individualized attention for everyone. Catering to both male and female individuals, the center's reliance on proven methods and commitment to excellent care position it as a leading option for individuals pursuing impactful rehabilitation.

Placeholder image

The NCWR Addiction Recovery Clinic at OSU in Tulsa, OK, provides outpatient detox and treatment services for adults dealing with serious mental health issues alongside substance use disorders. Employing methods such as brief interventions, cognitive behavioral techniques, and motivational interviewing, this center delivers personalized support for both men and women. It emphasizes outpatient care with specialized treatment options like methadone, buprenorphine, or naltrexone tailored to fit the distinct requirements of each client. With an emphasis on high-quality care and a dedication to fostering enduring recovery, this clinic offers a nurturing space for individuals seeking extensive addiction treatment solutions.

Placeholder image

NE Delta Human Servs Authority, located in Monroe, LA, delivers extensive support for substance use disorders and provides specialized interventions for those facing combined mental health and addiction challenges. The center features robust intensive outpatient and standard outpatient services, incorporating medication-assisted treatments such as methadone, buprenorphine, or naltrexone. Employing scientifically validated methods like cognitive behavioral therapy and the Matrix Model, this establishment serves individuals across the lifespan, from children and adolescents to adults. Distinctive offerings for active military personnel, young people, and adult men ensure personalized therapeutic experiences. Catering to a diverse clientele of all genders, this center is dedicated to delivering high-quality, client-centered care aimed at fostering enduring sobriety.

Placeholder image

Situated in New York, NY, the Neighborhood Coalition for Shelter Inc delivers an extensive array of treatment options for substance use aimed at both adults and young adults. This center is dedicated to assisting those with simultaneous substance use issues and significant mental health challenges. Treatment includes intensive outpatient care, outpatient services, and options for methadone/buprenorphine or naltrexone in an outpatient setting. The facility employs evidence-based methods such as anger management, brief interventions, and cognitive behavioral therapy. Offering specialized programs designed for adult men, adult women, and individuals with trauma backgrounds, this center emphasizes personalized care to address varying requirements. It serves both male and female clients in need of effective rehabilitation support.

Frequently Asked Questions

What is buprenorphine and how does it treat opioid addiction?
Buprenorphine is a partial opioid agonist medication approved by the FDA for treating opioid use disorder. It binds to the same receptors as heroin and fentanyl but produces a much weaker effect, reducing cravings and withdrawal symptoms without causing intense euphoria. Buprenorphine has a ceiling effect, meaning its opioid effects plateau at moderate doses, making it safer than methadone in terms of overdose risk.
What is the difference between Suboxone and Subutex?
Suboxone contains two active ingredients — buprenorphine and naloxone — while Subutex contains only buprenorphine without naloxone. The naloxone in Suboxone is included as an abuse deterrent; it remains inactive when taken sublingually as prescribed but triggers withdrawal if the medication is injected. Subutex is generally reserved for patients who cannot tolerate naloxone, such as pregnant women.
What is a Sublocade injection and how does it work?
Sublocade is a once-monthly injectable form of buprenorphine administered as a subcutaneous injection in the abdominal area. After injection, the medication forms a solid deposit under the skin that slowly releases buprenorphine over the course of a month. This eliminates daily dosing and removes the possibility of missed doses or medication diversion.
What are the common side effects of Suboxone?
Common Suboxone side effects include headache, nausea, constipation, insomnia, sweating, and mouth numbness or pain from sublingual administration. Some patients also experience dizziness, drowsiness, and blurred vision, particularly when starting treatment. Most side effects diminish within the first few weeks as the body adjusts. Patients should report difficulty breathing or signs of allergic reaction immediately.
What happens during Suboxone withdrawal?
Suboxone withdrawal occurs when a patient stops taking the medication abruptly after prolonged use, with symptoms including muscle aches, anxiety, insomnia, nausea, and irritability. A medically supervised taper is strongly recommended, typically reducing the dose by small increments over weeks or months. The risk of opioid relapse is significantly higher during unsupervised discontinuation.
How does Suboxone compare to methadone?
Suboxone and methadone are both effective for opioid use disorder but differ in key ways. Methadone is a full opioid agonist dispensed daily at licensed clinics, while Suboxone is a partial agonist that can be prescribed by qualified physicians and taken at home. Suboxone carries a lower overdose risk due to its ceiling effect and offers greater convenience, though methadone may be more appropriate for patients with severe, long-standing dependence.
How can I find a Suboxone clinic or doctor near me?
The most reliable way to find a Suboxone provider is through SAMHSA's online treatment locator at findtreatment.gov, which allows you to search by location and filter for buprenorphine providers. Many primary care offices, addiction treatment centers, and telehealth platforms now offer Suboxone prescriptions following the elimination of the federal X-waiver requirement in early 2023.
What is Zubsolv and how is it different from Suboxone?
Zubsolv is a brand-name buprenorphine and naloxone sublingual tablet that features a mint flavor and dissolves faster under the tongue than other options. Due to its higher bioavailability, Zubsolv uses different dosing strengths — a Zubsolv 5.7 mg/1.4 mg tablet is considered equivalent to a Suboxone 8 mg/2 mg dose. Patients switching between products should work closely with their prescriber for correct dose conversion.
Does Medicaid cover Suboxone treatment?
Yes — Medicaid covers buprenorphine (including Suboxone, Sublocade, Subutex, Zubsolv, and Brixadi) for opioid use disorder in all 50 states, as required by the SUPPORT Act of 2018. Medicaid is the largest single payer for MAT in the US. Coverage details vary by state — some require prior authorization or limit certain formulations. Many OBOT clinics accept Medicaid directly; telehealth Suboxone providers also bill Medicaid in most states. Bring your Medicaid card to your intake appointment.
Can I get Suboxone through telehealth?
Yes. After the MAT Act of 2023 permanently eliminated the X-waiver requirement, any licensed prescriber can prescribe Suboxone via telehealth in most states. The DEA also extended COVID-era telehealth flexibilities through at least 2025, allowing virtual Suboxone induction without a prior in-person visit. Several specialty platforms — Bicycle Health, Ophelia, Workit Health, Boulder Care — offer Medicaid-accepting telehealth Suboxone treatment. Telehealth has dramatically expanded access in rural and underserved areas with no nearby OBOT physicians.

About Buprenorphine (Suboxone)

Buprenorphine is classified as a partial opioid agonist, meaning it activates opioid receptors in the brain but to a much lesser degree than full agonists such as heroin, fentanyl, or oxycodone. This partial activation suppresses withdrawal symptoms and reduces cravings without producing dangerous respiratory depression or intense euphoria. Buprenorphine also has an unusually high binding affinity for the mu-opioid receptor, effectively blocking other opioids from attaching — providing a protective effect against relapse-related overdose.

How Buprenorphine Works

One of the defining features of buprenorphine is its ceiling effect — after a certain dose threshold, increasing the amount does not produce additional opioid effects. This dramatically reduces the risk of fatal overdose compared to methadone or illicit opioids. The ceiling effect, combined with its long duration of action (24 to 72 hours), makes buprenorphine one of the safest and most effective tools in medication-assisted treatment (MAT). Approved by the FDA in 2002, buprenorphine was a breakthrough because it could be prescribed in outpatient settings rather than requiring daily clinic visits.

Buprenorphine Brand Comparison: Suboxone, Subutex, Sublocade, Zubsolv, Brixadi

Buprenorphine is available under several FDA-approved brand names, each with distinct formulations, dosing schedules, and clinical use cases. The comparison below highlights the key differences:

BrandActive ingredientFormFrequencySettingFDA yearBest for
SuboxoneBuprenorphine + naloxoneSublingual film / tabletDailyOBOT, telehealth, retail pharmacy2002Most prescribed; naloxone deters injection misuse
SubutexBuprenorphine (alone)Sublingual tabletDailyOBOT2002Pregnancy; documented naloxone sensitivity
SublocadeBuprenorphine extended-releaseSubcutaneous injection (ATRIGEL depot)MonthlyClinic-administered2017No daily dosing; eliminates diversion risk
ZubsolvBuprenorphine + naloxoneSublingual tablet (higher bioavailability)DailyOBOT2013Faster dissolution; mint flavor; lower mg/dose
BrixadiBuprenorphine extended-releaseSubcutaneous injectionWeekly or monthlyClinic2023Newer alternative to Sublocade; weekly option for induction

All five medications are Schedule III controlled substances and equivalent in clinical efficacy at appropriate doses. The choice depends on adherence patterns, lifestyle, insurance coverage, and clinical context (e.g., pregnancy, prior injection use, daily-dosing burden). Many patients begin on sublingual Suboxone for stabilization and transition to monthly Sublocade or weekly Brixadi after sustained recovery.

Buprenorphine Side Effects

Common buprenorphine side effects include:

  • Headache and dizziness
  • Nausea and vomiting, especially during induction
  • Constipation and insomnia
  • Excessive sweating
  • Mouth numbness or oral discomfort from sublingual formulations

More serious side effects may include respiratory depression (particularly when combined with benzodiazepines or alcohol), liver problems, and allergic reactions. For most patients, side effects are mild and resolve within one to two weeks. The benefits in preventing relapse and overdose death significantly outweigh the risks.

Buprenorphine Dosage and Induction

Treatment begins with an induction phase where the patient must be in mild to moderate opioid withdrawal. Common induction doses range from 2 mg to 8 mg on the first day, with increases over the following days. Most patients stabilize on 8 mg to 24 mg per day, with 16 mg being the most commonly prescribed dose. Research suggests doses of 16 mg or higher are associated with better retention and outcomes. Dosage should always be adjusted under medical supervision.

Buprenorphine/Naloxone Combination

Many buprenorphine formulations include naloxone as an abuse deterrent. When taken sublingually as directed, naloxone has very low bioavailability and produces no clinical effect. However, if someone attempts to inject the medication, the naloxone component becomes fully active and triggers severe withdrawal. This design discourages injection misuse while having no impact on patients who take the medication correctly. The combination is the standard first-line formulation for opioid addiction treatment.

Suboxone: Sublingual Buprenorphine

Suboxone is the most recognized brand name for buprenorphine-naloxone and is most commonly dispensed as a sublingual film (Suboxone strips) that dissolves under the tongue. Suboxone has transformed opioid treatment by enabling millions of patients to receive effective pharmacotherapy in outpatient settings without the daily clinic visits required by methadone programs.

Suboxone Side Effects

Commonly reported Suboxone side effects include headache, nausea, tongue or mouth irritation, constipation, insomnia, sweating, and decreased libido. The sublingual film can cause irritation or small sores inside the mouth — rotating placement between under the tongue and against the cheek helps minimize this. Patients should not eat, drink, or smoke while the film is dissolving.

Suboxone Strips: Film vs. Tablet

Suboxone strips (sublingual film) have largely replaced the original tablet form. The film dissolves more quickly (two to four minutes), provides more consistent absorption, and is harder to divert due to individual foil packaging. Generic buprenorphine-naloxone tablets are often less expensive and may be preferred for cost reasons. Both are therapeutically equivalent when taken as prescribed.

Suboxone Treatment Programs

Comprehensive Suboxone treatment typically includes three phases:

  • Induction: Initial dosing under medical supervision, requiring the patient to be in early withdrawal
  • Stabilization: Dose adjustment until cravings and withdrawal are minimal, usually one to two months
  • Maintenance: Stable dosing for an extended period — often a year or longer — combined with counseling and behavioral therapy

Evidence consistently shows that longer treatment durations are associated with better outcomes. Most addiction medicine experts recommend a minimum of one to two years of maintenance therapy.

Find a Suboxone Clinic Near You — OBOT & Telehealth Options

Finding a Suboxone clinic has become significantly easier since the federal government eliminated the X-waiver requirement in January 2023, meaning any provider with a standard DEA license can now prescribe Suboxone. Patients can search SAMHSA's treatment locator at findtreatment.gov or use our directory to locate nearby facilities that offer buprenorphine-based treatment.

Suboxone Doctors Near Me

Beyond SAMHSA's locator, many state health departments maintain directories of addiction treatment providers. Telehealth has dramatically expanded access — several platforms now offer virtual Suboxone consultations, which is especially valuable for patients in rural areas. When selecting a provider, look for those offering comprehensive treatment including counseling, not just medication prescriptions.

Suboxone Withdrawal and Tapering

Suboxone withdrawal can include muscle aches, anxiety, insomnia, nausea, sweating, and intense opioid cravings. A gradual, medically supervised taper is recommended — typically reducing the dose by 10 to 25 percent every one to four weeks. Slower tapers over several months produce fewer symptoms and lower relapse rates. There is no medically mandated time limit for Suboxone treatment, and many patients benefit from indefinite maintenance.

Suboxone vs Methadone

Suboxone can be prescribed in office settings and taken at home, carries lower overdose risk due to its ceiling effect, and offers greater scheduling flexibility. Methadone is a full agonist that may be more effective for severe, long-standing dependence but must be dispensed at licensed clinics with daily visits. Neither is inherently superior — the best choice keeps the patient in treatment. Some patients may also benefit from naltrexone, a non-opioid alternative.

Sublocade: Monthly Buprenorphine Injection

Sublocade delivers buprenorphine as a once-monthly subcutaneous injection in the abdominal area using the ATRIGEL delivery system, which forms a solid biodegradable depot that slowly releases medication. Patients must first stabilize on sublingual buprenorphine (8 mg+ daily) for at least seven days. Treatment typically begins with two 300 mg injections, followed by maintenance on 300 mg or 100 mg. Sublocade eliminates concerns about daily adherence, missed doses, and medication diversion.

Sublocade Side Effects

The most common Sublocade side effects are injection-site reactions (pain, itching, redness, or a noticeable lump), nausea, constipation, headache, and fatigue. The injection-site lump is normal and gradually diminishes as medication is absorbed. Patients should avoid rubbing or massaging the site. Elevated liver enzymes may also occur but are usually mild and transient.

Subutex: Buprenorphine Without Naloxone

Subutex was the original brand-name buprenorphine product. While the brand has been discontinued, generic buprenorphine-only tablets remain available. Buprenorphine monotherapy is typically reserved for pregnant patients (to avoid naloxone exposure to the fetus), patients with documented naloxone sensitivity, or sometimes during the induction phase before transitioning to the combination product.

Subutex vs Suboxone

The primary difference is the absence of naloxone in Subutex. Because Subutex lacks the abuse-deterrent naloxone component, it may carry slightly higher diversion risk, and many insurance formularies prioritize the combination as the default. Current clinical guidelines favor buprenorphine-only formulations primarily for pregnancy and naloxone sensitivity.

Zubsolv: Alternative Buprenorphine Brand

Zubsolv is a buprenorphine-naloxone sublingual tablet featuring a mint flavor and faster dissolution (under two minutes). Due to enhanced bioavailability, Zubsolv uses different dose strengths — a 5.7 mg/1.4 mg tablet equals a Suboxone 8 mg/2 mg dose. Zubsolv is available in multiple strengths for flexible dosing during both induction and maintenance.

Buprenorphine resources:

Find Buprenorphine (Suboxone) by State

Browse buprenorphine (suboxone) programs in states with the most treatment options.

Explore Related Options

Related conditions, treatment approaches, and levels of care.

Medically Reviewed Updated August 2026

Reviewed by licensed addiction specialists. Information reflects current clinical guidance.

Sources:SAMHSA·NIDA·CDC

Need immediate help? Call SAMHSA: 1-800-662-4357 (24/7, free)