NWVCIL Logo
Medically Reviewed Content
Updated: August 2026
Sources: SAMHSA, NIDA

Suboxone Clinic Near You: Buprenorphine Treatment for Opioid Addiction

Find a Suboxone clinic near you. Buprenorphine — sold under brand names Suboxone, Sublocade, Subutex, Zubsolv, and Brixadi — is the most-prescribed MAT for opioid use disorder. It is a partial mu-opioid agonist with a ceiling effect that dramatically reduces overdose risk vs. methadone. After the MAT Act of 2023 eliminated the X-waiver requirement, any licensed prescriber can prescribe buprenorphine in office-based settings (OBOT), via telehealth, or at retail pharmacies. Buprenorphine is a Schedule III controlled substance and is covered by Medicaid in all 50 states.

Found 7,145 treatment centers offering buprenorphine (suboxone) across the United States.

Need Help Finding the Right Treatment Center?

Speak with a compassionate specialist now - 100% free & confidential

Call +1 (833) 244-3031
Available 24/7
All 50 States
Filters:

Showing 21 of 7145 results

NorthKey Community Care

Situated in Florence, KY, NorthKey Community Care provides an extensive array of programs for the treatment of substance use disorders and co-occurring mental health issues for both adults and children. The facility offers intensive outpatient therapy, standard outpatient services, and various medication-assisted treatments, including methadone, buprenorphine, and naltrexone. NorthKey Community Care emphasizes methods such as anger management, brief intervention techniques, and cognitive behavioral therapy, catering to adult men and women, as well as individuals who have faced intimate partner or domestic violence. Dedicated to serving adults and seniors of all genders, this center focuses on delivering personalized, high-quality care to assist clients on their journey toward recovery.

NorthKey Community Care

Situated in Covington, KY, NorthKey Community Care provides dedicated rehabilitation services aimed at adults and seniors facing challenges related to substance use and mental health. The center offers a variety of treatment options including intensive outpatient programs, outpatient services, and medications such as methadone/buprenorphine or naltrexone. Emphasizing techniques like anger management, brief interventions, and cognitive behavioral therapy, NorthKey serves both men and women, including those affected by domestic violence. The facility designs specific programs and gender-sensitive support to foster a nurturing atmosphere for individuals on their recovery journey. Rely on NorthKey Community Care for thorough and effective rehabilitation solutions.

NorthKey Community Care

Situated in Newport, KY, NorthKey Community Care provides a wide range of treatment options for individuals dealing with substance use disorders, alongside serious mental health challenges. Their services encompass intensive outpatient programs, standard outpatient care, and specialized treatments involving methadone, buprenorphine, or naltrexone. The center employs methods such as anger management and cognitive behavioral therapy to deliver personalized support for both men and women, including those impacted by domestic violence. NorthKey Community Care is dedicated to serving adults and seniors of every gender, emphasizing high-quality care and proven strategies to assist individuals in their recovery journey.

NorthKey Community Care

NorthKey Community Care in Carrollton, KY, delivers dedicated substance use and co-occurring disorder services for individuals of all ages. The center features intensive outpatient and standard outpatient options, incorporating methadone and buprenorphine therapies. Emphasizing anger management, cognitive behavioral techniques, and short-term counseling, programs are customized for each person's unique requirements. Specialized tracks are available for adult men and women, and for survivors of intimate partner violence. NorthKey Community Care provides excellent care to adults and older adults, embracing a kind and all-encompassing rehabilitation philosophy.

Northlake Behavioral Health System

Situated in Mandeville, LA, Northlake Behavioral Health System delivers a wide range of rehabilitation services tailored for both adults and children. The center specializes in detoxification, treatment for substance use disorders, and managing co-occurring conditions, offering 24/7 inpatient care. The program features 12-step facilitation, strategies for anger management, and brief interventions. With services geared towards active duty military members and adults of all genders, Northlake Behavioral Health System serves a variety of demographics. Their customized approach and specialized programs for various age groups and genders ensure high-quality support and care for individuals on their path to recovery from addiction and mental health issues.

NorthLakes Community Clinic

Situated in Turtle Lake, WI, NorthLakes Community Clinic specializes in outpatient services for adults dealing with substance use disorders and serious mental health conditions, in addition to addressing emotional challenges in children. The clinic employs a variety of techniques, including anger management, brief intervention, and cognitive behavioral therapy, to deliver regular outpatient support. NorthLakes Community Clinic emphasizes personalized treatment plans for adults and seniors across all genders. The facility's dedication to providing high-quality care and customized programs makes it an essential asset for individuals in need of effective rehabilitation in a nurturing setting.

NorthLakes Community Clinic

Situated in Hayward, WI, NorthLakes Community Clinic stands out as a leading rehabilitation facility, dedicated to addressing substance use issues alongside co-occurring mental health challenges. The center offers a variety of outpatient services, featuring methadone and buprenorphine treatment as well as cognitive behavioral therapy. Distinctive programs specifically designed for adult women and those who have undergone trauma highlight the clinic’s commitment to personalized care. NorthLakes Community Clinic serves adults and seniors across all gender identities, emphasizing an inclusive approach to recovery. With a strong emphasis on anger management and short-term interventions, this center provides exceptional support for individuals on their path to health and recovery.

NorthLakes Community Clinic

NorthLakes Community Clinic, located in Ashland, WI, delivers outpatient services that concentrate on addressing substance use and co-occurring mental health issues in both adults and children. This center provides customized treatment options, including anger management, cognitive behavioral therapy, and short-term intervention strategies. It features specialized programs for those who have experienced trauma as well as individuals involved in the criminal justice system. Catering to adults and seniors across all gender identities, the clinic provides outpatient methadone/buprenorphine or naltrexone therapies alongside standard outpatient services. With a commitment to high-quality and personalized care, NorthLakes Community Clinic stands out as a reliable choice for individuals in need of comprehensive rehabilitation support.

Northpoint Recovery

Northpoint Recovery in Meridian, ID, provides extensive care for adults and young adults struggling with addiction and related mental health challenges. They offer inpatient hospital detoxification and treatment, with tailored options for active military, adult men, and adult women. Employing methods such as 12-step facilitation, anger management, and brief intervention, Northpoint Recovery serves all genders. Their commitment to high-quality, personalized treatment aims to support individuals in attaining sustained recovery and enhanced mental health.

NorthSight Recovery

Situated in Tempe, AZ, NorthSight Recovery provides a wide array of addiction treatment options. This center features services such as detox, various levels of substance use therapy, transitional accommodations, halfway houses, and sober living environments. NorthSight Recovery supports adults and young adults of all genders through different treatment methods, including intensive outpatient, outpatient, and day programs. The facility excels in 12-step facilitation, anger management techniques, and brief intervention strategies. Moreover, NorthSight Recovery has tailored programs for adult males, individuals dealing with trauma, and those with co-occurring mental health and substance use issues. Prioritizing high-quality care and personalized treatment plans, NorthSight Recovery stands as a reliable choice for individuals on their path to recovery.

Northstar Recovery Center

Northstar Recovery Center, situated in Southborough, MA, provides thorough addiction treatment for both adults and young adults. This center excels in addressing dual diagnoses, treating substance use disorders concurrently with significant mental health conditions in adults and emotional challenges in children. Employing strategies such as 12-step support, emotional regulation techniques, and short-term counseling, Northstar offers intensive outpatient, standard outpatient, and partial hospitalization programs. Specialized care is available for active military personnel, as well as distinct programs for adult men and women, ensuring a personalized recovery journey. Northstar's dedication to high standards of care and customized treatment plans positions it as a leading option for individuals pursuing successful recovery.

NorthKey Community Care
Williamstown, KY

NorthKey Community Care, located in Williamstown, KY, provides extensive addiction recovery solutions for individuals of all ages facing dual diagnoses of substance use disorders and mental health issues. Their offerings encompass high-intensity outpatient care, standard outpatient services, and tailored medication-assisted treatment options including methadone and buprenorphine. Employing therapeutic modalities such as anger resolution, early intervention, and cognitive-behavioral techniques, this center serves adult men and women, alongside survivors of relationship violence. Catering to adults and older adults, regardless of gender, NorthKey Community Care delivers effective support and dedicated assistance for those pursuing sobriety and mental wellness.

NorthKey Community Care

NorthKey Community Care in Warsaw, KY, delivers thorough treatment for addiction and specialized support for adults with dual diagnoses of substance use and severe mental health conditions, alongside children struggling with emotional disturbances. The facility offers intensive outpatient, outpatient, and standard outpatient services incorporating techniques such as anger management, brief interventions, and cognitive behavioral therapy. Recognizing diverse needs, NorthKey Community Care has developed specific programs for adult men, women, and individuals affected by intimate partner violence, serving adults and seniors regardless of gender. Discover effective care and encouragement at this center focused on complete well-being.

NorthKey Community Care

NorthKey Community Care, located in Falmouth, KY, delivers thorough care for adults facing substance use disorders alongside mental health issues, and for children experiencing significant emotional distress. The facility offers robust outpatient services, including intensive options, and employs medication-assisted treatments like methadone, buprenorphine, and naltrexone. Employing strategies such as anger management, cognitive behavioral therapy, and brief intervention techniques, NorthKey Community Care serves a diverse population including adults of all ages, seniors, and survivors of intimate partner or domestic violence. By providing customized care plans that consider age and gender, NorthKey Community Care is dedicated to delivering exceptional support for individuals pursuing freedom from addiction and mental health concerns.

Northstar Behavioral Health Network

Northstar Behavioral Health Network, situated in Saint Paul, MN, specializes in rehabilitation services for adult males facing challenges related to substance abuse and serious co-occurring mental health issues. The center offers a variety of treatments, including long-term, short-term, and 24-hour residential programs designed to cater to the unique requirements of each individual. Emphasizing methods such as 12-step facilitation, anger management, and brief intervention strategies, Northstar Behavioral Health Network is recognized for its all-encompassing recovery model. The facility additionally provides targeted programs for individuals who have undergone domestic violence, intimate partner violence, and sexual abuse. Committed to delivering exceptional care, this center is a prime option for adult men in search of comprehensive rehabilitation services within a nurturing atmosphere.

Northstar Health Systems

Situated in Bayonne, NJ, Northstar Health Systems provides an extensive array of services for addiction rehabilitation. The facility is focused on detoxification and treatment for substance use disorders among both adults and young adults. Offering various programs, including intensive outpatient services and outpatient detox, Northstar Health Systems addresses the needs of those pursuing recovery. The center features specialized programs tailored for adolescents, men, and women, ensuring that each person's care is customized to their specific needs. Their treatment methods incorporate strategies such as 12-step facilitation, anger management, and brief intervention, all aimed at facilitating comprehensive recovery. Northstar Health Systems is dedicated to offering exceptional care within a nurturing atmosphere.

Northpointe Council Inc

Northpointe Council Inc, located in Lockport, NY, provides extensive care for substance use disorders via multiple outpatient options, including methadone and buprenorphine services. Their treatment modalities are grounded in proven methods such as cognitive behavioral therapy and anger management techniques. This center distinguishes itself with specific services designed for distinct populations, including active duty military personnel, teenagers, and adult men. Catering to a broad spectrum of individuals, from adults to children and adolescents of any gender, Northpointe Council Inc ensures personalized support for a wide array of requirements. The dedication to high-quality treatment and customized recovery plans positions Northpointe Council Inc as a premier facility for those pursuing successful and nurturing addiction recovery.

Placeholder image

Situated in Wyoming, MN, Northstar Behavioral Health Network provides focused treatment for substance use disorders in both adults and young adults dealing with significant mental health challenges. The center offers a range of programs including long-term, short-term, and around-the-clock residential care, customized to meet the specific requirements of each individual. Emphasizing methods such as 12-step facilitation, anger management, and brief intervention strategies, this facility is particularly dedicated to assisting adult women who have encountered intimate partner violence, domestic abuse, or sexual assault. Northstar Behavioral Health Network distinguishes itself through its holistic approach and personalized programs aimed at empowering female clients throughout their recovery process.

Placeholder image

Situated in Saint Paul, MN, Northstar Behavioral Health Network specializes in addiction treatment specifically designed for adult women. This center delivers thorough care for those facing dual challenges of substance use and significant emotional issues. Treatment options are diverse, featuring long-term, short-term, and round-the-clock residential programs. Emphasizing 12-step support, anger management techniques, and short interventions, the facility addresses the needs of adults and young adults affected by intimate partner violence, domestic abuse, or sexual trauma. Northstar Behavioral Health Network is dedicated to offering effective, gender-focused care, guiding clients along their path to recovery.

Placeholder image

Northstar Behavioral Health Network, situated in Fergus Falls, MN, stands as a leading addiction recovery center dedicated to assisting adult men in overcoming substance dependency. This establishment provides diverse care modalities, encompassing hospital-level inpatient services, extended residential stays, and round-the-clock residential support. Emphasizing methodologies such as 12-step program integration, emotional regulation strategies, and short-term counseling, the center delivers customized assistance for individuals managing coexisting mental health and addiction challenges. Northstar Behavioral Health Network is equipped to serve adult and younger adult males, fostering a nurturing atmosphere conducive to healing. Discover exceptional support and individualized recovery plans at this respected institution.

Placeholder image

Northstar Behavioral Health Network, located in Saint Paul, MN, provides distinct rehabilitative services designed for individuals facing substance abuse challenges and concurrent serious mental health conditions in adults, as well as emotional disorders in young individuals. They offer flexible treatment durations, including extended, brief, and immediate residential care, personalizing recovery plans with methods like 12-step support, emotional regulation strategies, and concise intervention techniques. Distinctive offerings are available for adult men, victims of domestic abuse, intimate partner violence, and sexual assault. This establishment caters to adult males and adolescents, guaranteeing a focused and thorough treatment journey. The center's dedication to personalized support and specialized initiatives positions it as a premier destination for those desiring effective rehabilitative care.

Frequently Asked Questions

What is buprenorphine and how does it treat opioid addiction?
Buprenorphine is a partial opioid agonist medication approved by the FDA for treating opioid use disorder. It binds to the same receptors as heroin and fentanyl but produces a much weaker effect, reducing cravings and withdrawal symptoms without causing intense euphoria. Buprenorphine has a ceiling effect, meaning its opioid effects plateau at moderate doses, making it safer than methadone in terms of overdose risk.
What is the difference between Suboxone and Subutex?
Suboxone contains two active ingredients — buprenorphine and naloxone — while Subutex contains only buprenorphine without naloxone. The naloxone in Suboxone is included as an abuse deterrent; it remains inactive when taken sublingually as prescribed but triggers withdrawal if the medication is injected. Subutex is generally reserved for patients who cannot tolerate naloxone, such as pregnant women.
What is a Sublocade injection and how does it work?
Sublocade is a once-monthly injectable form of buprenorphine administered as a subcutaneous injection in the abdominal area. After injection, the medication forms a solid deposit under the skin that slowly releases buprenorphine over the course of a month. This eliminates daily dosing and removes the possibility of missed doses or medication diversion.
What are the common side effects of Suboxone?
Common Suboxone side effects include headache, nausea, constipation, insomnia, sweating, and mouth numbness or pain from sublingual administration. Some patients also experience dizziness, drowsiness, and blurred vision, particularly when starting treatment. Most side effects diminish within the first few weeks as the body adjusts. Patients should report difficulty breathing or signs of allergic reaction immediately.
What happens during Suboxone withdrawal?
Suboxone withdrawal occurs when a patient stops taking the medication abruptly after prolonged use, with symptoms including muscle aches, anxiety, insomnia, nausea, and irritability. A medically supervised taper is strongly recommended, typically reducing the dose by small increments over weeks or months. The risk of opioid relapse is significantly higher during unsupervised discontinuation.
How does Suboxone compare to methadone?
Suboxone and methadone are both effective for opioid use disorder but differ in key ways. Methadone is a full opioid agonist dispensed daily at licensed clinics, while Suboxone is a partial agonist that can be prescribed by qualified physicians and taken at home. Suboxone carries a lower overdose risk due to its ceiling effect and offers greater convenience, though methadone may be more appropriate for patients with severe, long-standing dependence.
How can I find a Suboxone clinic or doctor near me?
The most reliable way to find a Suboxone provider is through SAMHSA's online treatment locator at findtreatment.gov, which allows you to search by location and filter for buprenorphine providers. Many primary care offices, addiction treatment centers, and telehealth platforms now offer Suboxone prescriptions following the elimination of the federal X-waiver requirement in early 2023.
What is Zubsolv and how is it different from Suboxone?
Zubsolv is a brand-name buprenorphine and naloxone sublingual tablet that features a mint flavor and dissolves faster under the tongue than other options. Due to its higher bioavailability, Zubsolv uses different dosing strengths — a Zubsolv 5.7 mg/1.4 mg tablet is considered equivalent to a Suboxone 8 mg/2 mg dose. Patients switching between products should work closely with their prescriber for correct dose conversion.
Does Medicaid cover Suboxone treatment?
Yes — Medicaid covers buprenorphine (including Suboxone, Sublocade, Subutex, Zubsolv, and Brixadi) for opioid use disorder in all 50 states, as required by the SUPPORT Act of 2018. Medicaid is the largest single payer for MAT in the US. Coverage details vary by state — some require prior authorization or limit certain formulations. Many OBOT clinics accept Medicaid directly; telehealth Suboxone providers also bill Medicaid in most states. Bring your Medicaid card to your intake appointment.
Can I get Suboxone through telehealth?
Yes. After the MAT Act of 2023 permanently eliminated the X-waiver requirement, any licensed prescriber can prescribe Suboxone via telehealth in most states. The DEA also extended COVID-era telehealth flexibilities through at least 2025, allowing virtual Suboxone induction without a prior in-person visit. Several specialty platforms — Bicycle Health, Ophelia, Workit Health, Boulder Care — offer Medicaid-accepting telehealth Suboxone treatment. Telehealth has dramatically expanded access in rural and underserved areas with no nearby OBOT physicians.

About Buprenorphine (Suboxone)

Buprenorphine is classified as a partial opioid agonist, meaning it activates opioid receptors in the brain but to a much lesser degree than full agonists such as heroin, fentanyl, or oxycodone. This partial activation suppresses withdrawal symptoms and reduces cravings without producing dangerous respiratory depression or intense euphoria. Buprenorphine also has an unusually high binding affinity for the mu-opioid receptor, effectively blocking other opioids from attaching — providing a protective effect against relapse-related overdose.

How Buprenorphine Works

One of the defining features of buprenorphine is its ceiling effect — after a certain dose threshold, increasing the amount does not produce additional opioid effects. This dramatically reduces the risk of fatal overdose compared to methadone or illicit opioids. The ceiling effect, combined with its long duration of action (24 to 72 hours), makes buprenorphine one of the safest and most effective tools in medication-assisted treatment (MAT). Approved by the FDA in 2002, buprenorphine was a breakthrough because it could be prescribed in outpatient settings rather than requiring daily clinic visits.

Buprenorphine Brand Comparison: Suboxone, Subutex, Sublocade, Zubsolv, Brixadi

Buprenorphine is available under several FDA-approved brand names, each with distinct formulations, dosing schedules, and clinical use cases. The comparison below highlights the key differences:

BrandActive ingredientFormFrequencySettingFDA yearBest for
SuboxoneBuprenorphine + naloxoneSublingual film / tabletDailyOBOT, telehealth, retail pharmacy2002Most prescribed; naloxone deters injection misuse
SubutexBuprenorphine (alone)Sublingual tabletDailyOBOT2002Pregnancy; documented naloxone sensitivity
SublocadeBuprenorphine extended-releaseSubcutaneous injection (ATRIGEL depot)MonthlyClinic-administered2017No daily dosing; eliminates diversion risk
ZubsolvBuprenorphine + naloxoneSublingual tablet (higher bioavailability)DailyOBOT2013Faster dissolution; mint flavor; lower mg/dose
BrixadiBuprenorphine extended-releaseSubcutaneous injectionWeekly or monthlyClinic2023Newer alternative to Sublocade; weekly option for induction

All five medications are Schedule III controlled substances and equivalent in clinical efficacy at appropriate doses. The choice depends on adherence patterns, lifestyle, insurance coverage, and clinical context (e.g., pregnancy, prior injection use, daily-dosing burden). Many patients begin on sublingual Suboxone for stabilization and transition to monthly Sublocade or weekly Brixadi after sustained recovery.

Buprenorphine Side Effects

Common buprenorphine side effects include:

  • Headache and dizziness
  • Nausea and vomiting, especially during induction
  • Constipation and insomnia
  • Excessive sweating
  • Mouth numbness or oral discomfort from sublingual formulations

More serious side effects may include respiratory depression (particularly when combined with benzodiazepines or alcohol), liver problems, and allergic reactions. For most patients, side effects are mild and resolve within one to two weeks. The benefits in preventing relapse and overdose death significantly outweigh the risks.

Buprenorphine Dosage and Induction

Treatment begins with an induction phase where the patient must be in mild to moderate opioid withdrawal. Common induction doses range from 2 mg to 8 mg on the first day, with increases over the following days. Most patients stabilize on 8 mg to 24 mg per day, with 16 mg being the most commonly prescribed dose. Research suggests doses of 16 mg or higher are associated with better retention and outcomes. Dosage should always be adjusted under medical supervision.

Buprenorphine/Naloxone Combination

Many buprenorphine formulations include naloxone as an abuse deterrent. When taken sublingually as directed, naloxone has very low bioavailability and produces no clinical effect. However, if someone attempts to inject the medication, the naloxone component becomes fully active and triggers severe withdrawal. This design discourages injection misuse while having no impact on patients who take the medication correctly. The combination is the standard first-line formulation for opioid addiction treatment.

Suboxone: Sublingual Buprenorphine

Suboxone is the most recognized brand name for buprenorphine-naloxone and is most commonly dispensed as a sublingual film (Suboxone strips) that dissolves under the tongue. Suboxone has transformed opioid treatment by enabling millions of patients to receive effective pharmacotherapy in outpatient settings without the daily clinic visits required by methadone programs.

Suboxone Side Effects

Commonly reported Suboxone side effects include headache, nausea, tongue or mouth irritation, constipation, insomnia, sweating, and decreased libido. The sublingual film can cause irritation or small sores inside the mouth — rotating placement between under the tongue and against the cheek helps minimize this. Patients should not eat, drink, or smoke while the film is dissolving.

Suboxone Strips: Film vs. Tablet

Suboxone strips (sublingual film) have largely replaced the original tablet form. The film dissolves more quickly (two to four minutes), provides more consistent absorption, and is harder to divert due to individual foil packaging. Generic buprenorphine-naloxone tablets are often less expensive and may be preferred for cost reasons. Both are therapeutically equivalent when taken as prescribed.

Suboxone Treatment Programs

Comprehensive Suboxone treatment typically includes three phases:

  • Induction: Initial dosing under medical supervision, requiring the patient to be in early withdrawal
  • Stabilization: Dose adjustment until cravings and withdrawal are minimal, usually one to two months
  • Maintenance: Stable dosing for an extended period — often a year or longer — combined with counseling and behavioral therapy

Evidence consistently shows that longer treatment durations are associated with better outcomes. Most addiction medicine experts recommend a minimum of one to two years of maintenance therapy.

Find a Suboxone Clinic Near You — OBOT & Telehealth Options

Finding a Suboxone clinic has become significantly easier since the federal government eliminated the X-waiver requirement in January 2023, meaning any provider with a standard DEA license can now prescribe Suboxone. Patients can search SAMHSA's treatment locator at findtreatment.gov or use our directory to locate nearby facilities that offer buprenorphine-based treatment.

Suboxone Doctors Near Me

Beyond SAMHSA's locator, many state health departments maintain directories of addiction treatment providers. Telehealth has dramatically expanded access — several platforms now offer virtual Suboxone consultations, which is especially valuable for patients in rural areas. When selecting a provider, look for those offering comprehensive treatment including counseling, not just medication prescriptions.

Suboxone Withdrawal and Tapering

Suboxone withdrawal can include muscle aches, anxiety, insomnia, nausea, sweating, and intense opioid cravings. A gradual, medically supervised taper is recommended — typically reducing the dose by 10 to 25 percent every one to four weeks. Slower tapers over several months produce fewer symptoms and lower relapse rates. There is no medically mandated time limit for Suboxone treatment, and many patients benefit from indefinite maintenance.

Suboxone vs Methadone

Suboxone can be prescribed in office settings and taken at home, carries lower overdose risk due to its ceiling effect, and offers greater scheduling flexibility. Methadone is a full agonist that may be more effective for severe, long-standing dependence but must be dispensed at licensed clinics with daily visits. Neither is inherently superior — the best choice keeps the patient in treatment. Some patients may also benefit from naltrexone, a non-opioid alternative.

Sublocade: Monthly Buprenorphine Injection

Sublocade delivers buprenorphine as a once-monthly subcutaneous injection in the abdominal area using the ATRIGEL delivery system, which forms a solid biodegradable depot that slowly releases medication. Patients must first stabilize on sublingual buprenorphine (8 mg+ daily) for at least seven days. Treatment typically begins with two 300 mg injections, followed by maintenance on 300 mg or 100 mg. Sublocade eliminates concerns about daily adherence, missed doses, and medication diversion.

Sublocade Side Effects

The most common Sublocade side effects are injection-site reactions (pain, itching, redness, or a noticeable lump), nausea, constipation, headache, and fatigue. The injection-site lump is normal and gradually diminishes as medication is absorbed. Patients should avoid rubbing or massaging the site. Elevated liver enzymes may also occur but are usually mild and transient.

Subutex: Buprenorphine Without Naloxone

Subutex was the original brand-name buprenorphine product. While the brand has been discontinued, generic buprenorphine-only tablets remain available. Buprenorphine monotherapy is typically reserved for pregnant patients (to avoid naloxone exposure to the fetus), patients with documented naloxone sensitivity, or sometimes during the induction phase before transitioning to the combination product.

Subutex vs Suboxone

The primary difference is the absence of naloxone in Subutex. Because Subutex lacks the abuse-deterrent naloxone component, it may carry slightly higher diversion risk, and many insurance formularies prioritize the combination as the default. Current clinical guidelines favor buprenorphine-only formulations primarily for pregnancy and naloxone sensitivity.

Zubsolv: Alternative Buprenorphine Brand

Zubsolv is a buprenorphine-naloxone sublingual tablet featuring a mint flavor and faster dissolution (under two minutes). Due to enhanced bioavailability, Zubsolv uses different dose strengths — a 5.7 mg/1.4 mg tablet equals a Suboxone 8 mg/2 mg dose. Zubsolv is available in multiple strengths for flexible dosing during both induction and maintenance.

Buprenorphine resources:

Find Buprenorphine (Suboxone) by State

Browse buprenorphine (suboxone) programs in states with the most treatment options.

Explore Related Options

Related conditions, treatment approaches, and levels of care.

Medically Reviewed Updated August 2026

Reviewed by licensed addiction specialists. Information reflects current clinical guidance.

Sources:SAMHSA·NIDA·CDC

Need immediate help? Call SAMHSA: 1-800-662-4357 (24/7, free)