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Medically Reviewed Content
Updated: August 2026
Sources: SAMHSA, NIDA

Suboxone Clinic Near You: Buprenorphine Treatment for Opioid Addiction

Find a Suboxone clinic near you. Buprenorphine — sold under brand names Suboxone, Sublocade, Subutex, Zubsolv, and Brixadi — is the most-prescribed MAT for opioid use disorder. It is a partial mu-opioid agonist with a ceiling effect that dramatically reduces overdose risk vs. methadone. After the MAT Act of 2023 eliminated the X-waiver requirement, any licensed prescriber can prescribe buprenorphine in office-based settings (OBOT), via telehealth, or at retail pharmacies. Buprenorphine is a Schedule III controlled substance and is covered by Medicaid in all 50 states.

Found 7,145 treatment centers offering buprenorphine (suboxone) across the United States.

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Nystrom and Associates Ltd

Nystrom and Associates Ltd, located in Saint Paul, MN, provides a full spectrum of substance use care across multiple modalities such as intensive outpatient, standard outpatient, and medication-assisted treatment (methadone/buprenorphine or naltrexone). Their expertise lies in incorporating 12-step facilitation, anger management techniques, and brief intervention strategies. The center develops personalized treatment plans for young people, adult men, and adult women, catering to both adolescent and adult populations. Serving both male and female individuals, Nystrom and Associates Ltd is committed to delivering high-quality care within a nurturing setting. For those in search of successful addiction treatment that emphasizes customized services and unique program offerings, this organization is devoted to supporting your journey toward wellness.

Oakdale Recovery Center

Oakdale Recovery Center, situated in Canton, MI, offers extensive addiction recovery programs for adults and adolescents. Their services include inpatient detoxification, round-the-clock residential support, and brief residential stays. Oakdale Recovery Center is particularly adept at addressing co-occurring substance use disorders and significant mental health challenges in adults, alongside emotional issues in younger individuals. They utilize proven methods like 12-step facilitation, cognitive behavioral therapy, and contingency management. The center provides tailored programs for individuals with co-occurring disorders, ensuring personalized treatment for both men and women in a nurturing setting designed for impactful recovery.

Nystrom and Associates Ltd

Nystrom and Associates Ltd, located in Big Lake, MN, provides an extensive variety of treatment options for individuals dealing with substance abuse and concomitant mental health disorders, catering to both adults and children. The center offers flexible choices, including long-term, short-term, and 24-hour residential care, designed to meet the unique requirements of each client. Employing methodologies such as 12-step support, anger management techniques, and brief intervention strategies, Nystrom and Associates Ltd formulates customized treatment plans. With a strong emphasis on personalizing care, the center ensures that each individual receives focused attention and support throughout their recovery journey. The center welcomes both males and females, creating an encouraging atmosphere for healing.

Nystrom and Associates Ltd

Nystrom and Associates Ltd, situated in Baxter, MN, provides a full spectrum of substance abuse recovery options. Their offerings include intensive outpatient care, general outpatient services, and medication-assisted treatment with methadone, buprenorphine, or naltrexone. Employing strategies such as 12-step facilitation, anger management techniques, and brief intervention, they support adolescents, adult men, and adult women. The facility welcomes both male and female patients of all ages, from children and adolescents to adults. Nystrom and Associates Ltd is dedicated to delivering high-quality, personalized addiction treatment.

Nystrom and Associates Ltd

Nystrom and Associates Ltd, located in Saint Paul, MN, specializes in providing comprehensive treatment for substance use disorders among both adults and teenagers. The center features various treatment modalities, including intensive outpatient programs, outpatient services, and options for methadone, buprenorphine, or naltrexone. Emphasizing 12-step approaches, anger management, and brief interventions, the facility designs its programs to address the unique needs of adult men, adult women, and adolescents. Nystrom and Associates Ltd is committed to offering exceptional care for those pursuing effective addiction recovery in a nurturing setting.

Nystrom and Associates Ltd

Nystrom and Associates Ltd, situated in Rochester, MN, provides a wide range of treatment options for substance use disorders for both adults and teenagers. The center features intensive outpatient programs, standard outpatient services, as well as specific outpatient treatments with methadone/buprenorphine or naltrexone. Emphasizing methods like 12-step support, anger management, and brief interventions, this facility serves adult men and women, along with adolescents. Nystrom and Associates Ltd develops customized treatment plans for every client, ensuring effective support for both genders. If you're looking for a nurturing setting for addiction recovery, this center is committed to guiding you toward sustained sobriety.

Nystrom and Associates Ltd

Nystrom and Associates Ltd, located in Eden Prairie, MN, delivers extensive addiction treatment services aimed at both adults and teenagers. This facility offers various programs, including intensive outpatient therapy, standard outpatient care, and targeted treatments with methadone/buprenorphine or naltrexone. Emphasizing techniques like 12-step support, anger management, and brief interventions, the center addresses the unique needs of adult men, adult women, and adolescents. Gender-specific programs ensure personalized approaches to care. Nystrom and Associates Ltd stands out for its commitment to providing high-quality addiction rehabilitation, making it a preferred option for those in search of effective and empathetic treatment in the Eden Prairie region.

Nystrom and Associates Ltd

Nystrom and Associates Ltd, located in Minneapolis, MN, provides a wide range of substance use treatment options along with tailored support for individuals facing both substance use issues and significant mental health challenges or emotional struggles. The facility features intensive outpatient programs, standard outpatient services, and specialized treatments using methadone, buprenorphine, or naltrexone. Emphasizing approaches such as 12-step support, brief intervention techniques, and cognitive behavioral therapy, this center serves adult males and females, including those who have suffered from intimate partner or domestic violence. Catering to both adults and children/adolescents, it also offers gender-specific programs. Patients can look forward to receiving exceptional, personalized treatment at this esteemed rehabilitation facility.

Nystrom and Associates Ltd

Situated in Hopkins, MN, Nystrom and Associates Ltd provides focused treatment for substance abuse among adults facing significant mental health challenges, alongside services for children dealing with severe emotional issues. The center features both intensive outpatient and outpatient programs, offering treatments like methadone/buprenorphine or naltrexone. With approaches including 12-step programs, anger management, and short interventions, the facility serves adult men and women, including those affected by intimate partner violence. Catering to both adult and child/adolescent clients, and offering gender-specific programs, Nystrom and Associates Ltd delivers holistic support in a nurturing setting.

Nystrom and Associates Ltd

Nystrom and Associates Ltd, located in Saint Paul, MN, provides an extensive range of substance use rehabilitation programs designed for adults, teenagers, and children. The center features intensive outpatient care, outpatient services, and specific therapies involving methadone, buprenorphine, or naltrexone. Emphasizing 12-step programs, anger management, and brief interventions, it serves both male and female participants. Tailored programs for adult men, adult women, and adolescents reinforce a personalized approach to treatment. Nystrom and Associates Ltd takes pride in offering high-quality, gender-sensitive rehabilitation to assist individuals on their journey toward recovery.

Oak Integrated Care
Mount Holly, NJ

Oak Integrated Care, situated in Mount Holly, NJ, delivers extensive addiction recovery support and expert services for adults managing concurrent serious mental health conditions. The center features outpatient options such as opioid agonist therapy (methadone/buprenorphine) or opioid antagonist treatment (naltrexone), along with cognitive behavioral therapy, anger management strategies, and brief intervention techniques. Tailored programs are available for active military members, adult men, and adult women, reflecting Oak Integrated Care's commitment to serving a wide range of individuals. This establishment is dedicated to providing high-quality, personalized care plans for adults and young adults of all genders, aiding them in their path toward lasting recovery.

Nystrom and Associates Ltd

Situated in Osseo, MN, Nystrom and Associates Ltd delivers a wide range of treatment programs for substance use tailored to both adults and teenagers. The center features intensive outpatient programs, general outpatient services, as well as options for outpatient treatment using methadone/buprenorphine or naltrexone. Emphasizing 12-step methods, anger management techniques, and brief intervention strategies, this facility serves clients of all genders. Additionally, there are specialized programs designed for adolescents, adult males, and adult females. Known for its commitment to high-quality care and personalized treatment strategies, Nystrom and Associates Ltd is devoted to assisting individuals on their recovery journey.

Nystrom and Associates Ltd

Nystrom and Associates Ltd, located in Duluth, MN, delivers tailored recovery services for individuals across all age groups, including adults, teenagers, and younger persons. They provide comprehensive treatment tiers such as intensive outpatient services, general outpatient care, and medication-assisted treatment including methadone, buprenorphine, or naltrexone. Employing methodologies like 12-step encouragement, emotional regulation training, and brief counseling, the facility addresses the distinct requirements of adult males, adult females, and adolescents. Nystrom and Associates Ltd is committed to delivering effective support for those pursuing freedom from addiction. Their gender-affirming programs foster a secure and understanding atmosphere for both male and female participants as they work toward lasting abstinence.

Nystrom and Associates Ltd

Nystrom and Associates Ltd, situated in Minneapolis, MN, delivers a wide range of substance use recovery programs designed for both adults and teenagers. The facility features intensive outpatient care, various outpatient offerings, and treatment options involving methadone/buprenorphine or naltrexone. Emphasizing 12-step methods, anger management techniques, and brief interventions, the center serves adult men, adult women, and adolescents. Its targeted programs for distinct age groups and genders guarantee personalized support for each person. Nystrom and Associates Ltd is committed to providing effective, research-supported treatment to aid individuals in their recovery process.

Nystrom and Associates Ltd

Nystrom and Associates Ltd, located in Hutchinson, MN, provides comprehensive outpatient treatment for substance use disorders. Their services include intensive outpatient programs, general outpatient care, and medication-assisted treatment with methadone, buprenorphine, or naltrexone. The center utilizes therapeutic approaches such as 12-step facilitation, anger management, and brief interventions. Nystrom and Associates Ltd supports adolescents, adult men, and adult women, offering gender-specific programming for both male and female clients, as well as care for children and adolescents. They are dedicated to delivering personalized and effective care to aid individuals in achieving and maintaining sobriety.

Nystrom and Associates Ltd

Nystrom and Associates Ltd located in Alexandria, MN, provides a wide range of treatment options for those struggling with substance use. The facility features intensive outpatient services, standard outpatient programs, and specialized treatments with methadone/buprenorphine or naltrexone. Emphasizing a 12-step recovery model, anger management strategies, and brief intervention techniques, the center serves adolescents, adult males, and adult females. Catering to both adults and younger populations, it ensures tailored care for male and female clients alike. Nystrom and Associates Ltd in Alexandria is dedicated to offering personalized, high-quality support to help individuals navigate their recovery journey from addiction.

Nystrom and Associates Ltd

Nystrom and Associates Ltd, located in Fergus Falls, MN, provides individualized programs for substance use recovery. The center specializes in intensive outpatient services, standard outpatient support, and treatments utilizing methadone, buprenorphine, or naltrexone. Emphasizing 12-step principles, anger management, and concise intervention methods, the facility addresses the needs of adolescents as well as adult men and women. Catering to both adults and younger clients, it ensures that services are tailored to meet the specific needs of each gender. Nystrom and Associates Ltd is recognized for its diverse approach to treatment and a strong dedication to helping individuals on their journey to overcoming substance use challenges.

Nystrom and Associates Ltd

Situated in Bemidji, MN, Nystrom and Associates Ltd specializes in a wide range of substance abuse treatment options for both adults and teenagers. The facility features intensive outpatient programs, standard outpatient services, as well as outpatient treatment using methadone, buprenorphine, or naltrexone. With an emphasis on 12-step support, anger management, and brief intervention strategies, Nystrom and Associates Ltd customizes its treatment plans to address the unique requirements of each client. The center offers specific programs aimed at adolescents, adult men, and adult women. Nystrom and Associates Ltd fosters an inclusive and supportive atmosphere for all clients, regardless of gender. Discover exceptional care and individualized treatment at this esteemed rehabilitation facility.

Nystrom and Associates Ltd

Nystrom and Associates Ltd, located in Moorhead, MN, delivers targeted substance abuse recovery programs for both young people and adults. Their offerings include comprehensive outpatient services, intensive outpatient care, and medication-assisted treatment options like methadone, buprenorphine, or naltrexone. The center employs evidence-based strategies such as 12-step integration, anger management training, and brief intervention techniques, ensuring a personalized approach to each client's recovery path. Dedicated programs are provided for adolescents, adult men, and adult women. At Nystrom and Associates Ltd, individuals of all ages and genders receive dedicated support and effective treatment to aid their return to wellness.

Nystrom and Associates Ltd

Nystrom and Associates Ltd, located in Mankato, MN, provides extensive support for individuals struggling with substance misuse. They offer various levels of care, including intensive outpatient, outpatient, and medication-assisted treatment options like methadone, buprenorphine, or naltrexone. The center is particularly skilled in utilizing approaches such as 12-step facilitation, anger management techniques, and brief intervention strategies. Nystrom and Associates Ltd designs personalized treatment for adolescents, adult men, and adult women, accommodating a wide range of ages and genders. Their services extend to care for children and adolescents, ensuring that each person receives a treatment plan developed specifically for their needs. This dedication to high-quality care and specialized programming establishes Nystrom and Associates Ltd as a leading provider of effective and compassionate addiction recovery services.

Oaklawn Psychiatric Center Inc

Oaklawn Psychiatric Center Inc, located in Goshen, IN, provides targeted outpatient support for individuals dealing with substance abuse and concurrent mental health issues, catering to both adults and children. Emphasizing strategies such as 12-step facilitation, anger management, and short-term interventions, this center customizes its approach to fit the unique requirements of each client. Specialized programs are available for adolescents, adult males, and individuals with dual diagnoses. The range of services includes outpatient options for methadone, buprenorphine, or naltrexone therapy, alongside standard outpatient counseling. Oaklawn Psychiatric Center Inc is committed to delivering high-quality rehabilitation care for both men and women in need.

Frequently Asked Questions

What is buprenorphine and how does it treat opioid addiction?
Buprenorphine is a partial opioid agonist medication approved by the FDA for treating opioid use disorder. It binds to the same receptors as heroin and fentanyl but produces a much weaker effect, reducing cravings and withdrawal symptoms without causing intense euphoria. Buprenorphine has a ceiling effect, meaning its opioid effects plateau at moderate doses, making it safer than methadone in terms of overdose risk.
What is the difference between Suboxone and Subutex?
Suboxone contains two active ingredients — buprenorphine and naloxone — while Subutex contains only buprenorphine without naloxone. The naloxone in Suboxone is included as an abuse deterrent; it remains inactive when taken sublingually as prescribed but triggers withdrawal if the medication is injected. Subutex is generally reserved for patients who cannot tolerate naloxone, such as pregnant women.
What is a Sublocade injection and how does it work?
Sublocade is a once-monthly injectable form of buprenorphine administered as a subcutaneous injection in the abdominal area. After injection, the medication forms a solid deposit under the skin that slowly releases buprenorphine over the course of a month. This eliminates daily dosing and removes the possibility of missed doses or medication diversion.
What are the common side effects of Suboxone?
Common Suboxone side effects include headache, nausea, constipation, insomnia, sweating, and mouth numbness or pain from sublingual administration. Some patients also experience dizziness, drowsiness, and blurred vision, particularly when starting treatment. Most side effects diminish within the first few weeks as the body adjusts. Patients should report difficulty breathing or signs of allergic reaction immediately.
What happens during Suboxone withdrawal?
Suboxone withdrawal occurs when a patient stops taking the medication abruptly after prolonged use, with symptoms including muscle aches, anxiety, insomnia, nausea, and irritability. A medically supervised taper is strongly recommended, typically reducing the dose by small increments over weeks or months. The risk of opioid relapse is significantly higher during unsupervised discontinuation.
How does Suboxone compare to methadone?
Suboxone and methadone are both effective for opioid use disorder but differ in key ways. Methadone is a full opioid agonist dispensed daily at licensed clinics, while Suboxone is a partial agonist that can be prescribed by qualified physicians and taken at home. Suboxone carries a lower overdose risk due to its ceiling effect and offers greater convenience, though methadone may be more appropriate for patients with severe, long-standing dependence.
How can I find a Suboxone clinic or doctor near me?
The most reliable way to find a Suboxone provider is through SAMHSA's online treatment locator at findtreatment.gov, which allows you to search by location and filter for buprenorphine providers. Many primary care offices, addiction treatment centers, and telehealth platforms now offer Suboxone prescriptions following the elimination of the federal X-waiver requirement in early 2023.
What is Zubsolv and how is it different from Suboxone?
Zubsolv is a brand-name buprenorphine and naloxone sublingual tablet that features a mint flavor and dissolves faster under the tongue than other options. Due to its higher bioavailability, Zubsolv uses different dosing strengths — a Zubsolv 5.7 mg/1.4 mg tablet is considered equivalent to a Suboxone 8 mg/2 mg dose. Patients switching between products should work closely with their prescriber for correct dose conversion.
Does Medicaid cover Suboxone treatment?
Yes — Medicaid covers buprenorphine (including Suboxone, Sublocade, Subutex, Zubsolv, and Brixadi) for opioid use disorder in all 50 states, as required by the SUPPORT Act of 2018. Medicaid is the largest single payer for MAT in the US. Coverage details vary by state — some require prior authorization or limit certain formulations. Many OBOT clinics accept Medicaid directly; telehealth Suboxone providers also bill Medicaid in most states. Bring your Medicaid card to your intake appointment.
Can I get Suboxone through telehealth?
Yes. After the MAT Act of 2023 permanently eliminated the X-waiver requirement, any licensed prescriber can prescribe Suboxone via telehealth in most states. The DEA also extended COVID-era telehealth flexibilities through at least 2025, allowing virtual Suboxone induction without a prior in-person visit. Several specialty platforms — Bicycle Health, Ophelia, Workit Health, Boulder Care — offer Medicaid-accepting telehealth Suboxone treatment. Telehealth has dramatically expanded access in rural and underserved areas with no nearby OBOT physicians.

About Buprenorphine (Suboxone)

Buprenorphine is classified as a partial opioid agonist, meaning it activates opioid receptors in the brain but to a much lesser degree than full agonists such as heroin, fentanyl, or oxycodone. This partial activation suppresses withdrawal symptoms and reduces cravings without producing dangerous respiratory depression or intense euphoria. Buprenorphine also has an unusually high binding affinity for the mu-opioid receptor, effectively blocking other opioids from attaching — providing a protective effect against relapse-related overdose.

How Buprenorphine Works

One of the defining features of buprenorphine is its ceiling effect — after a certain dose threshold, increasing the amount does not produce additional opioid effects. This dramatically reduces the risk of fatal overdose compared to methadone or illicit opioids. The ceiling effect, combined with its long duration of action (24 to 72 hours), makes buprenorphine one of the safest and most effective tools in medication-assisted treatment (MAT). Approved by the FDA in 2002, buprenorphine was a breakthrough because it could be prescribed in outpatient settings rather than requiring daily clinic visits.

Buprenorphine Brand Comparison: Suboxone, Subutex, Sublocade, Zubsolv, Brixadi

Buprenorphine is available under several FDA-approved brand names, each with distinct formulations, dosing schedules, and clinical use cases. The comparison below highlights the key differences:

BrandActive ingredientFormFrequencySettingFDA yearBest for
SuboxoneBuprenorphine + naloxoneSublingual film / tabletDailyOBOT, telehealth, retail pharmacy2002Most prescribed; naloxone deters injection misuse
SubutexBuprenorphine (alone)Sublingual tabletDailyOBOT2002Pregnancy; documented naloxone sensitivity
SublocadeBuprenorphine extended-releaseSubcutaneous injection (ATRIGEL depot)MonthlyClinic-administered2017No daily dosing; eliminates diversion risk
ZubsolvBuprenorphine + naloxoneSublingual tablet (higher bioavailability)DailyOBOT2013Faster dissolution; mint flavor; lower mg/dose
BrixadiBuprenorphine extended-releaseSubcutaneous injectionWeekly or monthlyClinic2023Newer alternative to Sublocade; weekly option for induction

All five medications are Schedule III controlled substances and equivalent in clinical efficacy at appropriate doses. The choice depends on adherence patterns, lifestyle, insurance coverage, and clinical context (e.g., pregnancy, prior injection use, daily-dosing burden). Many patients begin on sublingual Suboxone for stabilization and transition to monthly Sublocade or weekly Brixadi after sustained recovery.

Buprenorphine Side Effects

Common buprenorphine side effects include:

  • Headache and dizziness
  • Nausea and vomiting, especially during induction
  • Constipation and insomnia
  • Excessive sweating
  • Mouth numbness or oral discomfort from sublingual formulations

More serious side effects may include respiratory depression (particularly when combined with benzodiazepines or alcohol), liver problems, and allergic reactions. For most patients, side effects are mild and resolve within one to two weeks. The benefits in preventing relapse and overdose death significantly outweigh the risks.

Buprenorphine Dosage and Induction

Treatment begins with an induction phase where the patient must be in mild to moderate opioid withdrawal. Common induction doses range from 2 mg to 8 mg on the first day, with increases over the following days. Most patients stabilize on 8 mg to 24 mg per day, with 16 mg being the most commonly prescribed dose. Research suggests doses of 16 mg or higher are associated with better retention and outcomes. Dosage should always be adjusted under medical supervision.

Buprenorphine/Naloxone Combination

Many buprenorphine formulations include naloxone as an abuse deterrent. When taken sublingually as directed, naloxone has very low bioavailability and produces no clinical effect. However, if someone attempts to inject the medication, the naloxone component becomes fully active and triggers severe withdrawal. This design discourages injection misuse while having no impact on patients who take the medication correctly. The combination is the standard first-line formulation for opioid addiction treatment.

Suboxone: Sublingual Buprenorphine

Suboxone is the most recognized brand name for buprenorphine-naloxone and is most commonly dispensed as a sublingual film (Suboxone strips) that dissolves under the tongue. Suboxone has transformed opioid treatment by enabling millions of patients to receive effective pharmacotherapy in outpatient settings without the daily clinic visits required by methadone programs.

Suboxone Side Effects

Commonly reported Suboxone side effects include headache, nausea, tongue or mouth irritation, constipation, insomnia, sweating, and decreased libido. The sublingual film can cause irritation or small sores inside the mouth — rotating placement between under the tongue and against the cheek helps minimize this. Patients should not eat, drink, or smoke while the film is dissolving.

Suboxone Strips: Film vs. Tablet

Suboxone strips (sublingual film) have largely replaced the original tablet form. The film dissolves more quickly (two to four minutes), provides more consistent absorption, and is harder to divert due to individual foil packaging. Generic buprenorphine-naloxone tablets are often less expensive and may be preferred for cost reasons. Both are therapeutically equivalent when taken as prescribed.

Suboxone Treatment Programs

Comprehensive Suboxone treatment typically includes three phases:

  • Induction: Initial dosing under medical supervision, requiring the patient to be in early withdrawal
  • Stabilization: Dose adjustment until cravings and withdrawal are minimal, usually one to two months
  • Maintenance: Stable dosing for an extended period — often a year or longer — combined with counseling and behavioral therapy

Evidence consistently shows that longer treatment durations are associated with better outcomes. Most addiction medicine experts recommend a minimum of one to two years of maintenance therapy.

Find a Suboxone Clinic Near You — OBOT & Telehealth Options

Finding a Suboxone clinic has become significantly easier since the federal government eliminated the X-waiver requirement in January 2023, meaning any provider with a standard DEA license can now prescribe Suboxone. Patients can search SAMHSA's treatment locator at findtreatment.gov or use our directory to locate nearby facilities that offer buprenorphine-based treatment.

Suboxone Doctors Near Me

Beyond SAMHSA's locator, many state health departments maintain directories of addiction treatment providers. Telehealth has dramatically expanded access — several platforms now offer virtual Suboxone consultations, which is especially valuable for patients in rural areas. When selecting a provider, look for those offering comprehensive treatment including counseling, not just medication prescriptions.

Suboxone Withdrawal and Tapering

Suboxone withdrawal can include muscle aches, anxiety, insomnia, nausea, sweating, and intense opioid cravings. A gradual, medically supervised taper is recommended — typically reducing the dose by 10 to 25 percent every one to four weeks. Slower tapers over several months produce fewer symptoms and lower relapse rates. There is no medically mandated time limit for Suboxone treatment, and many patients benefit from indefinite maintenance.

Suboxone vs Methadone

Suboxone can be prescribed in office settings and taken at home, carries lower overdose risk due to its ceiling effect, and offers greater scheduling flexibility. Methadone is a full agonist that may be more effective for severe, long-standing dependence but must be dispensed at licensed clinics with daily visits. Neither is inherently superior — the best choice keeps the patient in treatment. Some patients may also benefit from naltrexone, a non-opioid alternative.

Sublocade: Monthly Buprenorphine Injection

Sublocade delivers buprenorphine as a once-monthly subcutaneous injection in the abdominal area using the ATRIGEL delivery system, which forms a solid biodegradable depot that slowly releases medication. Patients must first stabilize on sublingual buprenorphine (8 mg+ daily) for at least seven days. Treatment typically begins with two 300 mg injections, followed by maintenance on 300 mg or 100 mg. Sublocade eliminates concerns about daily adherence, missed doses, and medication diversion.

Sublocade Side Effects

The most common Sublocade side effects are injection-site reactions (pain, itching, redness, or a noticeable lump), nausea, constipation, headache, and fatigue. The injection-site lump is normal and gradually diminishes as medication is absorbed. Patients should avoid rubbing or massaging the site. Elevated liver enzymes may also occur but are usually mild and transient.

Subutex: Buprenorphine Without Naloxone

Subutex was the original brand-name buprenorphine product. While the brand has been discontinued, generic buprenorphine-only tablets remain available. Buprenorphine monotherapy is typically reserved for pregnant patients (to avoid naloxone exposure to the fetus), patients with documented naloxone sensitivity, or sometimes during the induction phase before transitioning to the combination product.

Subutex vs Suboxone

The primary difference is the absence of naloxone in Subutex. Because Subutex lacks the abuse-deterrent naloxone component, it may carry slightly higher diversion risk, and many insurance formularies prioritize the combination as the default. Current clinical guidelines favor buprenorphine-only formulations primarily for pregnancy and naloxone sensitivity.

Zubsolv: Alternative Buprenorphine Brand

Zubsolv is a buprenorphine-naloxone sublingual tablet featuring a mint flavor and faster dissolution (under two minutes). Due to enhanced bioavailability, Zubsolv uses different dose strengths — a 5.7 mg/1.4 mg tablet equals a Suboxone 8 mg/2 mg dose. Zubsolv is available in multiple strengths for flexible dosing during both induction and maintenance.

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Medically Reviewed Updated August 2026

Reviewed by licensed addiction specialists. Information reflects current clinical guidance.

Sources:SAMHSA·NIDA·CDC

Need immediate help? Call SAMHSA: 1-800-662-4357 (24/7, free)