NWVCIL Logo
Medically Reviewed Content
Updated: August 2026
Sources: SAMHSA, NIDA

Suboxone Clinic Near You: Buprenorphine Treatment for Opioid Addiction

Find a Suboxone clinic near you. Buprenorphine — sold under brand names Suboxone, Sublocade, Subutex, Zubsolv, and Brixadi — is the most-prescribed MAT for opioid use disorder. It is a partial mu-opioid agonist with a ceiling effect that dramatically reduces overdose risk vs. methadone. After the MAT Act of 2023 eliminated the X-waiver requirement, any licensed prescriber can prescribe buprenorphine in office-based settings (OBOT), via telehealth, or at retail pharmacies. Buprenorphine is a Schedule III controlled substance and is covered by Medicaid in all 50 states.

Found 7,145 treatment centers offering buprenorphine (suboxone) across the United States.

Need Help Finding the Right Treatment Center?

Speak with a compassionate specialist now - 100% free & confidential

Call +1 (833) 244-3031
Available 24/7
All 50 States
Filters:

Showing 21 of 7145 results

Park Avenue Center
Minneapolis, MN

Located in Minneapolis, MN, Park Avenue Center provides in-depth substance use rehabilitation for adult males, featuring transitional housing and treatment for concurrent mental health conditions. The center offers both intensive outpatient and standard outpatient programs, utilizing 12-step approaches, anger management strategies, and brief counseling techniques. It includes specialized services aimed at individuals dealing with simultaneous pain and substance use disorders. Focused on adult, senior, and young adult men, this facility emphasizes tailored care and support for those on the path to recovery. Park Avenue Center's dedication to high-quality treatment positions it as a leading option for individuals seeking personalized and effective rehabilitation solutions.

Parkman Recovery Center

At Parkman Recovery Center in Warren, OH, we provide extensive addiction recovery programs designed exclusively for adult men. Our services encompass hospital-based inpatient detox, specialized substance use therapy, and supportive transitional living arrangements. We integrate proven therapeutic approaches like 12-step facilitation, anger management techniques, and cognitive behavioral therapy, serving adults of all ages who desire high-quality care. Our distinctive focus on the unique challenges faced by men allows for highly individualized treatment plans aimed at achieving enduring sobriety and successful community reintegration.

Partida Corona Medical Center

Partida Corona Medical Center, located in Las Vegas, NV, specializes in providing outpatient services aimed at detoxification, addressing substance use issues, and managing co-occurring disorders for both adults and minors. The facility offers various treatment options including outpatient detox, as well as methadone, buprenorphine, and naltrexone therapies. Emphasizing techniques such as anger management, brief interventions, and cognitive behavioral therapy, the center is dedicated to delivering personalized care. They serve individuals of all ages and genders, ensuring their approach is uniquely tailored to each client's needs. Partida Corona Medical Center is committed to delivering high-quality, comprehensive addiction treatment in a nurturing atmosphere.

Partners Project Inc
Huntington Beach, CA

Located in Huntington Beach, CA, Partners Project Inc provides a wide range of rehabilitation services for both adults and young adults struggling with substance abuse and concurrent mental health challenges. The center features inpatient detoxification and treatment plans, with particular attention to the needs of active duty military members. Utilizing customized strategies like 12-step engagement and anger management therapy, the facility serves clients of all genders. The emphasis on short-term interventions guarantees personalized and effective care. Partners Project Inc is distinguished by its unwavering dedication to high-quality support and its mission to assist individuals in attaining sustainable recovery.

Partners Project Inc
Huntington Beach, CA

Partners Project Inc, located in Huntington Beach, CA, provides extensive addiction recovery programs designed for both adults and young adults dealing with substance use disorders and simultaneous mental health issues. The center offers a range of specialized services, including inpatient detox and round-the-clock hospital care, ensuring customized support through techniques such as 12-step facilitation, anger management, and brief intervention strategies. The facility features distinct programs for active duty military members as well as tailored options for adult men and women, promoting personalized treatment. With a strong focus on delivering high-quality care, this center is dedicated to assisting clients of all genders in attaining lasting recovery.

Park Avenue Center
Minneapolis, MN

Situated in Minneapolis, MN, Park Avenue Center provides a thorough approach to substance abuse rehabilitation specifically for adult females. The center features transitional housing, a halfway house, and sober living arrangements. With expertise in addressing simultaneous substance use issues and significant mental health challenges in adults, in addition to severe emotional issues in children, the center offers both outpatient and intensive outpatient treatment options. Emphasizing 12-step programs, anger management techniques, and brief therapeutic interventions, Park Avenue Center serves individuals who have faced trauma and those with both mental health and substance use disorders. The center is committed to delivering high-quality care to adults, seniors, and young adults in a nurturing atmosphere.

Park Mental Health Treatment of

Park Mental Health Treatment in San Diego, CA, provides tailored support for adult men facing addiction and concurrent mental health challenges. The center offers robust partial hospitalization, intensive outpatient, and standard outpatient programs, serving adults across the age spectrum, including older adults and young adults. Their therapeutic modalities encompass 12-step integration, emotional regulation strategies, and short-term counseling. Park Mental Health Treatment distinguishes itself with specialized curricula for individuals with a history of trauma and those managing dual diagnoses. Emphasizing superior treatment and personalized recovery paths, this establishment is committed to guiding individuals toward lasting wellness.

Park Place Behavioral Healthcare

Park Place Behavioral Healthcare in Kissimmee, FL, delivers thorough substance abuse treatment for individuals of all ages struggling with addiction and associated mental health conditions. The facility provides various care levels, including intensive outpatient, extended residential stays, and standard outpatient services, with distinct programs designed for young people. Employing scientifically proven methods like 12-step support, brief counseling, and cognitive behavioral therapy, this center serves both men and women looking for high-caliber care in a nurturing setting. Park Place Behavioral Healthcare distinguishes itself through its integrated treatment plans customized for each person's specific circumstances, establishing it as a premier destination for effective and empathetic recovery assistance.

Parker Froyd and Associates

Parker Froyd and Associates, located in Denver, CO, specializes in outpatient services for adults dealing with substance use disorders and co-existing mental health challenges, while also addressing significant emotional issues in children. Their treatment options encompass 12-step programs, anger management, and brief intervention strategies. This center tailors its services to adolescents, as well as adult men and women, ensuring gender-specific care. Committed to providing exceptional support, they invite adults, children, and adolescents on their journey to recovery. Parker Froyd and Associates stands out as a reliable choice for individuals seeking effective, research-driven treatment within a nurturing setting.

Park Heights Health Services Inc

At Park Heights Health Services Inc in Baltimore, MD, we provide a full spectrum of care for adults and young adults struggling with substance use. Our services include intensive outpatient care, standard outpatient services, and medication-assisted treatment options such as methadone, buprenorphine, or naltrexone. We specialize in counseling for substance use disorders and offer the convenience of telemedicine and telehealth therapy. Our programs are designed for adult men, adult women, and members of the LGBTQ community. We believe in a personalized approach, recognizing that each person's journey is unique and requires tailored support. Park Heights Health Services Inc is dedicated to offering exceptional and effective recovery services for those pursuing freedom from addiction.

PARC Program
Rockport, ME

In Rockport, Maine, the PARC Program offers extensive recovery support for adults and young adults facing challenges with addiction and intertwined mental health conditions. This center provides inpatient hospital detox, therapeutic interventions, and round-the-clock supervision, featuring tailored programs for individuals with co-occurring disorders. Their treatment methodologies incorporate 12-step principles, emotional regulation strategies, and short-term intervention methods. Dedicated to personalized support, the PARC Program serves both male and female individuals, fostering a welcoming and affirming atmosphere. Discover exceptional support and custom treatment at this respected recovery facility.

Park Center Inc
Bluffton, IN

Park Center Inc, located in Bluffton, IN, provides targeted outpatient services for adults dealing with substance use disorders and co-occurring mental health issues, as well as addressing significant emotional challenges in children. The center employs a variety of treatment methodologies, such as anger management, brief intervention sessions, and cognitive behavioral therapy. Additionally, unique programs are available for individuals who have faced traumatic experiences. With a strong emphasis on personalized care for both adults and children/adolescents, Park Center Inc is dedicated to offering tailored treatment plans for all clients. The facility prioritizes an individualized approach and utilizes evidence-based methods, reflecting its dedication to delivering exceptional rehabilitation services.

Parkview Behavioral Health

Parkview Behavioral Health, located in Fort Wayne, IN, provides extensive treatment options for both adults and children dealing with substance use challenges and associated mental health conditions. The center features hospital-based detox services, around-the-clock inpatient support, and intensive outpatient programs, accommodating individuals of all genders. With targeted services for those experiencing simultaneous mental health and addiction issues, the facility emphasizes the importance of 12-step programs, anger management strategies, and short-term therapeutic interventions. Parkview Behavioral Health is recognized for its personalized treatment plans and dedication to high-quality care, establishing itself as a leading provider of empathetic addiction recovery solutions in the Fort Wayne region.

Placeholder image
Saint Paul, MN

Parity Wellness, located in Saint Paul, MN, delivers a complete spectrum of recovery support for adults and adolescents struggling with addiction and related mental health challenges. Their offerings encompass several treatment structures: intensive outpatient, outpatient, and standard outpatient options. Employing specialized techniques like brief intervention, cognitive behavioral therapy, and the Matrix Model, clients benefit from personalized care plans. Parity Wellness is distinguished by its specific programs for adult men and women, as well as those impacted by intimate partner or domestic violence. The center is dedicated to providing excellent support, prioritizing healing and overall wellness for everyone.

Placeholder image
Decatur, IN

Park Center Inc, located in Decatur, IN, offers a wide range of substance abuse treatment options for both adults and children dealing with concurrent mental health challenges. The facility provides various programs, including intensive outpatient, outpatient, and medication-assisted therapies, employing research-backed methods like cognitive behavioral therapy and anger management techniques. With a commitment to trauma-informed care, Park Center Inc serves individuals of all ages and genders, developing customized treatment strategies to foster enduring recovery. Prioritizing quality support and comprehensive healing, this center is a reliable choice for individuals in need of efficient rehabilitation services within a nurturing setting.

Placeholder image
Fort Wayne, IN

Park Center Inc, located in Fort Wayne, Indiana, stands out as a premier rehabilitation center that delivers tailored treatment for substance abuse as well as concurrent mental health issues in both adults and children. The facility encompasses both inpatient care and intensive outpatient services, utilizing proven methods such as 12-step programming, anger management strategies, and short-term interventions. Designed to meet the unique requirements of adolescents, adult males, and females, Park Center Inc supports a wide range of clients. With a dedication to providing holistic care, the center is dedicated to assisting both adult and youth clients in their recovery journey. Their focus on personalized treatment and high-quality services makes them a reliable option for those seeking to overcome challenges and achieve wellness.

Placeholder image
Columbia City, IN

Park Center Inc, located in Columbia City, IN, specializes in providing substance use treatment for adults with serious mental health disorders alongside children facing significant emotional challenges. The center offers various outpatient and intensive outpatient services, including treatments utilizing methadone/buprenorphine or naltrexone. With an emphasis on anger management, brief therapeutic interventions, and cognitive behavioral therapy, the facility is designed for those who have gone through traumatic experiences. Park Center Inc welcomes clients of all genders, ensuring personalized treatment for both adults and younger populations. Discover exceptional care and tailored programs at this well-appointed rehabilitation center.

Placeholder image

Park West Health System Inc, located in Baltimore, MD, provides focused treatment for adults struggling with substance use issues alongside mental health challenges, as well as for children facing significant emotional difficulties. The center's outpatient services feature intensive outpatient programs and medication-assisted treatment options, including methadone, buprenorphine, and naltrexone. Emphasizing techniques such as cognitive behavioral therapy, anger management, and quick therapeutic interventions, the facility delivers personalized care to active military members, teenagers, and adult males. Catering to a diverse population of adults and seniors, this center is dedicated to delivering high-quality care with customized treatment strategies aimed at fostering recovery and enhancing overall health.

Placeholder image

Parkside Outpatient Program in Astoria, NY, provides targeted care for adults struggling with substance use disorders, particularly when accompanied by serious mental health issues or emotional difficulties in younger individuals. This center delivers a range of services including intensive outpatient treatment, standard outpatient care, and medication-assisted options like methadone, buprenorphine, or naltrexone. They employ specialized therapeutic techniques such as 12-step facilitation, anger management, and brief interventions, serving adult men and women, as well as those with a history of trauma. The program is equipped to support both adult and pediatric/adolescent populations, offering personalized plans for both male and female participants. Parkside Outpatient Program is dedicated to delivering effective treatment, standing as a key provider for individuals pursuing recovery from addiction.

Placeholder image

Partners in Recovery/SPHS, situated in Rosedale, MD, delivers a full spectrum of addiction recovery solutions designed for adults and adolescents. Their services encompass safe detoxification, comprehensive substance use therapy, and tailored support for individuals managing both addiction and significant mental health challenges. Available treatment modalities include intensive outpatient programming, general outpatient services, and outpatient detoxification. Employing evidence-based strategies such as 12-step facilitation, brief intervention, and cognitive behavioral therapy, the center customizes treatment plans to address each person's unique journey. Specific programs are offered for active military personnel, adult men, and adult women. Partners in Recovery/SPHS is committed to providing high-quality care for all individuals, supporting both men and women on their path to wellness.

Placeholder image

Partners in Recovery/SPHS in Baltimore, MD, delivers complete addiction recovery programs for adults and younger adults. Their services encompass detoxification, treatment for substance dependency, and dedicated support for individuals facing both addiction and significant mental health challenges. Employing approaches like 12-step facilitation, brief intervention, and cognitive behavioral therapy, their offerings are customized to meet individual requirements. Specific tracks are available for active-duty military members, adult men, and adult women, providing targeted assistance. The facility provides outpatient and intensive outpatient care, emphasizing high-quality, personalized treatment for all clients, regardless of gender, on their journey to recovery.

Frequently Asked Questions

What is buprenorphine and how does it treat opioid addiction?
Buprenorphine is a partial opioid agonist medication approved by the FDA for treating opioid use disorder. It binds to the same receptors as heroin and fentanyl but produces a much weaker effect, reducing cravings and withdrawal symptoms without causing intense euphoria. Buprenorphine has a ceiling effect, meaning its opioid effects plateau at moderate doses, making it safer than methadone in terms of overdose risk.
What is the difference between Suboxone and Subutex?
Suboxone contains two active ingredients — buprenorphine and naloxone — while Subutex contains only buprenorphine without naloxone. The naloxone in Suboxone is included as an abuse deterrent; it remains inactive when taken sublingually as prescribed but triggers withdrawal if the medication is injected. Subutex is generally reserved for patients who cannot tolerate naloxone, such as pregnant women.
What is a Sublocade injection and how does it work?
Sublocade is a once-monthly injectable form of buprenorphine administered as a subcutaneous injection in the abdominal area. After injection, the medication forms a solid deposit under the skin that slowly releases buprenorphine over the course of a month. This eliminates daily dosing and removes the possibility of missed doses or medication diversion.
What are the common side effects of Suboxone?
Common Suboxone side effects include headache, nausea, constipation, insomnia, sweating, and mouth numbness or pain from sublingual administration. Some patients also experience dizziness, drowsiness, and blurred vision, particularly when starting treatment. Most side effects diminish within the first few weeks as the body adjusts. Patients should report difficulty breathing or signs of allergic reaction immediately.
What happens during Suboxone withdrawal?
Suboxone withdrawal occurs when a patient stops taking the medication abruptly after prolonged use, with symptoms including muscle aches, anxiety, insomnia, nausea, and irritability. A medically supervised taper is strongly recommended, typically reducing the dose by small increments over weeks or months. The risk of opioid relapse is significantly higher during unsupervised discontinuation.
How does Suboxone compare to methadone?
Suboxone and methadone are both effective for opioid use disorder but differ in key ways. Methadone is a full opioid agonist dispensed daily at licensed clinics, while Suboxone is a partial agonist that can be prescribed by qualified physicians and taken at home. Suboxone carries a lower overdose risk due to its ceiling effect and offers greater convenience, though methadone may be more appropriate for patients with severe, long-standing dependence.
How can I find a Suboxone clinic or doctor near me?
The most reliable way to find a Suboxone provider is through SAMHSA's online treatment locator at findtreatment.gov, which allows you to search by location and filter for buprenorphine providers. Many primary care offices, addiction treatment centers, and telehealth platforms now offer Suboxone prescriptions following the elimination of the federal X-waiver requirement in early 2023.
What is Zubsolv and how is it different from Suboxone?
Zubsolv is a brand-name buprenorphine and naloxone sublingual tablet that features a mint flavor and dissolves faster under the tongue than other options. Due to its higher bioavailability, Zubsolv uses different dosing strengths — a Zubsolv 5.7 mg/1.4 mg tablet is considered equivalent to a Suboxone 8 mg/2 mg dose. Patients switching between products should work closely with their prescriber for correct dose conversion.
Does Medicaid cover Suboxone treatment?
Yes — Medicaid covers buprenorphine (including Suboxone, Sublocade, Subutex, Zubsolv, and Brixadi) for opioid use disorder in all 50 states, as required by the SUPPORT Act of 2018. Medicaid is the largest single payer for MAT in the US. Coverage details vary by state — some require prior authorization or limit certain formulations. Many OBOT clinics accept Medicaid directly; telehealth Suboxone providers also bill Medicaid in most states. Bring your Medicaid card to your intake appointment.
Can I get Suboxone through telehealth?
Yes. After the MAT Act of 2023 permanently eliminated the X-waiver requirement, any licensed prescriber can prescribe Suboxone via telehealth in most states. The DEA also extended COVID-era telehealth flexibilities through at least 2025, allowing virtual Suboxone induction without a prior in-person visit. Several specialty platforms — Bicycle Health, Ophelia, Workit Health, Boulder Care — offer Medicaid-accepting telehealth Suboxone treatment. Telehealth has dramatically expanded access in rural and underserved areas with no nearby OBOT physicians.

About Buprenorphine (Suboxone)

Buprenorphine is classified as a partial opioid agonist, meaning it activates opioid receptors in the brain but to a much lesser degree than full agonists such as heroin, fentanyl, or oxycodone. This partial activation suppresses withdrawal symptoms and reduces cravings without producing dangerous respiratory depression or intense euphoria. Buprenorphine also has an unusually high binding affinity for the mu-opioid receptor, effectively blocking other opioids from attaching — providing a protective effect against relapse-related overdose.

How Buprenorphine Works

One of the defining features of buprenorphine is its ceiling effect — after a certain dose threshold, increasing the amount does not produce additional opioid effects. This dramatically reduces the risk of fatal overdose compared to methadone or illicit opioids. The ceiling effect, combined with its long duration of action (24 to 72 hours), makes buprenorphine one of the safest and most effective tools in medication-assisted treatment (MAT). Approved by the FDA in 2002, buprenorphine was a breakthrough because it could be prescribed in outpatient settings rather than requiring daily clinic visits.

Buprenorphine Brand Comparison: Suboxone, Subutex, Sublocade, Zubsolv, Brixadi

Buprenorphine is available under several FDA-approved brand names, each with distinct formulations, dosing schedules, and clinical use cases. The comparison below highlights the key differences:

BrandActive ingredientFormFrequencySettingFDA yearBest for
SuboxoneBuprenorphine + naloxoneSublingual film / tabletDailyOBOT, telehealth, retail pharmacy2002Most prescribed; naloxone deters injection misuse
SubutexBuprenorphine (alone)Sublingual tabletDailyOBOT2002Pregnancy; documented naloxone sensitivity
SublocadeBuprenorphine extended-releaseSubcutaneous injection (ATRIGEL depot)MonthlyClinic-administered2017No daily dosing; eliminates diversion risk
ZubsolvBuprenorphine + naloxoneSublingual tablet (higher bioavailability)DailyOBOT2013Faster dissolution; mint flavor; lower mg/dose
BrixadiBuprenorphine extended-releaseSubcutaneous injectionWeekly or monthlyClinic2023Newer alternative to Sublocade; weekly option for induction

All five medications are Schedule III controlled substances and equivalent in clinical efficacy at appropriate doses. The choice depends on adherence patterns, lifestyle, insurance coverage, and clinical context (e.g., pregnancy, prior injection use, daily-dosing burden). Many patients begin on sublingual Suboxone for stabilization and transition to monthly Sublocade or weekly Brixadi after sustained recovery.

Buprenorphine Side Effects

Common buprenorphine side effects include:

  • Headache and dizziness
  • Nausea and vomiting, especially during induction
  • Constipation and insomnia
  • Excessive sweating
  • Mouth numbness or oral discomfort from sublingual formulations

More serious side effects may include respiratory depression (particularly when combined with benzodiazepines or alcohol), liver problems, and allergic reactions. For most patients, side effects are mild and resolve within one to two weeks. The benefits in preventing relapse and overdose death significantly outweigh the risks.

Buprenorphine Dosage and Induction

Treatment begins with an induction phase where the patient must be in mild to moderate opioid withdrawal. Common induction doses range from 2 mg to 8 mg on the first day, with increases over the following days. Most patients stabilize on 8 mg to 24 mg per day, with 16 mg being the most commonly prescribed dose. Research suggests doses of 16 mg or higher are associated with better retention and outcomes. Dosage should always be adjusted under medical supervision.

Buprenorphine/Naloxone Combination

Many buprenorphine formulations include naloxone as an abuse deterrent. When taken sublingually as directed, naloxone has very low bioavailability and produces no clinical effect. However, if someone attempts to inject the medication, the naloxone component becomes fully active and triggers severe withdrawal. This design discourages injection misuse while having no impact on patients who take the medication correctly. The combination is the standard first-line formulation for opioid addiction treatment.

Suboxone: Sublingual Buprenorphine

Suboxone is the most recognized brand name for buprenorphine-naloxone and is most commonly dispensed as a sublingual film (Suboxone strips) that dissolves under the tongue. Suboxone has transformed opioid treatment by enabling millions of patients to receive effective pharmacotherapy in outpatient settings without the daily clinic visits required by methadone programs.

Suboxone Side Effects

Commonly reported Suboxone side effects include headache, nausea, tongue or mouth irritation, constipation, insomnia, sweating, and decreased libido. The sublingual film can cause irritation or small sores inside the mouth — rotating placement between under the tongue and against the cheek helps minimize this. Patients should not eat, drink, or smoke while the film is dissolving.

Suboxone Strips: Film vs. Tablet

Suboxone strips (sublingual film) have largely replaced the original tablet form. The film dissolves more quickly (two to four minutes), provides more consistent absorption, and is harder to divert due to individual foil packaging. Generic buprenorphine-naloxone tablets are often less expensive and may be preferred for cost reasons. Both are therapeutically equivalent when taken as prescribed.

Suboxone Treatment Programs

Comprehensive Suboxone treatment typically includes three phases:

  • Induction: Initial dosing under medical supervision, requiring the patient to be in early withdrawal
  • Stabilization: Dose adjustment until cravings and withdrawal are minimal, usually one to two months
  • Maintenance: Stable dosing for an extended period — often a year or longer — combined with counseling and behavioral therapy

Evidence consistently shows that longer treatment durations are associated with better outcomes. Most addiction medicine experts recommend a minimum of one to two years of maintenance therapy.

Find a Suboxone Clinic Near You — OBOT & Telehealth Options

Finding a Suboxone clinic has become significantly easier since the federal government eliminated the X-waiver requirement in January 2023, meaning any provider with a standard DEA license can now prescribe Suboxone. Patients can search SAMHSA's treatment locator at findtreatment.gov or use our directory to locate nearby facilities that offer buprenorphine-based treatment.

Suboxone Doctors Near Me

Beyond SAMHSA's locator, many state health departments maintain directories of addiction treatment providers. Telehealth has dramatically expanded access — several platforms now offer virtual Suboxone consultations, which is especially valuable for patients in rural areas. When selecting a provider, look for those offering comprehensive treatment including counseling, not just medication prescriptions.

Suboxone Withdrawal and Tapering

Suboxone withdrawal can include muscle aches, anxiety, insomnia, nausea, sweating, and intense opioid cravings. A gradual, medically supervised taper is recommended — typically reducing the dose by 10 to 25 percent every one to four weeks. Slower tapers over several months produce fewer symptoms and lower relapse rates. There is no medically mandated time limit for Suboxone treatment, and many patients benefit from indefinite maintenance.

Suboxone vs Methadone

Suboxone can be prescribed in office settings and taken at home, carries lower overdose risk due to its ceiling effect, and offers greater scheduling flexibility. Methadone is a full agonist that may be more effective for severe, long-standing dependence but must be dispensed at licensed clinics with daily visits. Neither is inherently superior — the best choice keeps the patient in treatment. Some patients may also benefit from naltrexone, a non-opioid alternative.

Sublocade: Monthly Buprenorphine Injection

Sublocade delivers buprenorphine as a once-monthly subcutaneous injection in the abdominal area using the ATRIGEL delivery system, which forms a solid biodegradable depot that slowly releases medication. Patients must first stabilize on sublingual buprenorphine (8 mg+ daily) for at least seven days. Treatment typically begins with two 300 mg injections, followed by maintenance on 300 mg or 100 mg. Sublocade eliminates concerns about daily adherence, missed doses, and medication diversion.

Sublocade Side Effects

The most common Sublocade side effects are injection-site reactions (pain, itching, redness, or a noticeable lump), nausea, constipation, headache, and fatigue. The injection-site lump is normal and gradually diminishes as medication is absorbed. Patients should avoid rubbing or massaging the site. Elevated liver enzymes may also occur but are usually mild and transient.

Subutex: Buprenorphine Without Naloxone

Subutex was the original brand-name buprenorphine product. While the brand has been discontinued, generic buprenorphine-only tablets remain available. Buprenorphine monotherapy is typically reserved for pregnant patients (to avoid naloxone exposure to the fetus), patients with documented naloxone sensitivity, or sometimes during the induction phase before transitioning to the combination product.

Subutex vs Suboxone

The primary difference is the absence of naloxone in Subutex. Because Subutex lacks the abuse-deterrent naloxone component, it may carry slightly higher diversion risk, and many insurance formularies prioritize the combination as the default. Current clinical guidelines favor buprenorphine-only formulations primarily for pregnancy and naloxone sensitivity.

Zubsolv: Alternative Buprenorphine Brand

Zubsolv is a buprenorphine-naloxone sublingual tablet featuring a mint flavor and faster dissolution (under two minutes). Due to enhanced bioavailability, Zubsolv uses different dose strengths — a 5.7 mg/1.4 mg tablet equals a Suboxone 8 mg/2 mg dose. Zubsolv is available in multiple strengths for flexible dosing during both induction and maintenance.

Buprenorphine resources:

Find Buprenorphine (Suboxone) by State

Browse buprenorphine (suboxone) programs in states with the most treatment options.

Explore Related Options

Related conditions, treatment approaches, and levels of care.

Medically Reviewed Updated August 2026

Reviewed by licensed addiction specialists. Information reflects current clinical guidance.

Sources:SAMHSA·NIDA·CDC

Need immediate help? Call SAMHSA: 1-800-662-4357 (24/7, free)