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Medically Reviewed Content
Updated: August 2026
Sources: SAMHSA, NIDA

Suboxone Clinic Near You: Buprenorphine Treatment for Opioid Addiction

Find a Suboxone clinic near you. Buprenorphine — sold under brand names Suboxone, Sublocade, Subutex, Zubsolv, and Brixadi — is the most-prescribed MAT for opioid use disorder. It is a partial mu-opioid agonist with a ceiling effect that dramatically reduces overdose risk vs. methadone. After the MAT Act of 2023 eliminated the X-waiver requirement, any licensed prescriber can prescribe buprenorphine in office-based settings (OBOT), via telehealth, or at retail pharmacies. Buprenorphine is a Schedule III controlled substance and is covered by Medicaid in all 50 states.

Found 7,145 treatment centers offering buprenorphine (suboxone) across the United States.

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Recovery Works
Martinsville, IN

Recovery Works, situated in Martinsville, IN, provides extensive addiction recovery support for adults and adolescents. Their offerings include detox services, intensive outpatient, outpatient, and day treatment options. Recovery Works emphasizes 12-step facilitation, anger management techniques, and brief intervention strategies, serving both male and female clients, including survivors of domestic abuse. This institution distinguishes itself with tailored programs for adult men and women, and a commitment to delivering excellent care for those aiming to conquer substance dependency.

Recovery Works
London, KY

Recovery Works, situated in London, KY, delivers a full spectrum of substance abuse treatment for adults and adolescents. Their offerings include extended residential stays, inpatient detoxification, and round-the-clock residential services. Recovery Works is particularly adept at addressing dual diagnoses of addiction and severe mental health conditions in adults, as well as significant emotional challenges in children. The center employs strategies such as 12-step facilitation, anger management techniques, and brief intervention methods. Tailored programs are provided for adult men, adult women, and individuals impacted by domestic abuse. Committed to high-quality, individualized care, Recovery Works is devoted to guiding clients toward lasting sobriety.

Recovery Works
Martinsville, IN

Nestled in Martinsville, IN, Recovery Works provides a complete spectrum of addiction recovery care. This facility offers detox, drug and alcohol treatment, supportive housing, and sober living environments for those embarking on a journey to sobriety. Through varied treatment modalities like intensive outpatient, extended residential stays, and standard outpatient care, Recovery Works meets a wide array of individual requirements. Employing therapeutic techniques such as 12-step integration, anger management, and cognitive behavioral therapy, the center ensures tailored support. Specific services are extended to active duty military members, adult men, and women. Catering to adults and young adults across all genders, Recovery Works is dedicated to delivering effective, science-backed treatment for sustained sobriety.

Recovery Works
South Shore, KY

Recovery Works, situated in South Shore, KY, delivers a full spectrum of addiction recovery programs. Their services encompass detox, substance use disorder therapy, and supported living environments like sober living residences and halfway houses. Offering flexible treatment modalities such as intensive outpatient, outpatient, and partial hospitalization, Recovery Works serves adults and adolescents of all genders. They also provide specialized support for active military, adult men, and adult women. The center employs diverse therapeutic methods including 12-step facilitation, anger management, and brief interventions, promoting personalized care plans. Select Recovery Works for effective, research-backed treatment in a nurturing setting.

Recovery Works Covington

Recovery Works Covington, situated in Covington, Kentucky, provides a range of services including outpatient detox, treatment for substance use, and tailored programs for women who are pregnant or in the postpartum phase. This facility is designed to accommodate both adults and young adults of all genders, ensuring a welcoming environment. The center employs various methodologies, including brief interventions, the Matrix Model, and motivational interviewing, to create personalized treatment strategies for each individual. Committed to delivering high-quality care and evidence-based solutions, Recovery Works Covington aims to assist individuals in their recovery journey from addiction.

Recovery Works Healing Center LLC

Recovery Works Healing Center LLC, located in Dayton, OH, provides targeted interventions for individuals struggling with addiction, mental health challenges, and developmental disorders in youth. Their program structure includes intensive outpatient and standard outpatient detoxification options, employing scientifically validated therapeutic modalities like cognitive behavioral therapy, motivational interviewing, and anger management techniques. These services are customized to suit the specific requirements of adults, young adults, and children across all gender identities. Emphasizing a distinctive approach to individualized support, this establishment cultivates a thorough and empathetic setting for those pursuing successful recovery.

Recovery Works NW

Situated in Newberg, OR, Recovery Works NW offers a wide range of outpatient treatment options for substance use tailored to both adults and young adults. The center is particularly adept at addressing the needs of individuals with dual diagnoses, offering customized programs for male and female clients. Recovery Works NW employs proven strategies like cognitive behavioral therapy and motivational interviewing to provide effective and personalized treatment. The center also features outpatient options for methadone/buprenorphine or naltrexone, prioritizing individualized care that aims at fostering lasting recovery. If you are looking for a nurturing and specialized atmosphere for treatment, this facility is committed to helping individuals find a path to enduring sobriety.

Recovery Works NW
Portland, OR

Recovery Works NW in Portland, OR, provides focused outpatient care for individuals of all ages dealing with substance use disorders and concurrent severe mental health challenges. The center offers diverse treatment modalities, such as medication-assisted treatment utilizing methadone, buprenorphine, or naltrexone, alongside standard outpatient services. Employing proven therapeutic strategies like CBT and motivational interviewing, this facility serves adult men and women, as well as those with dual diagnoses. Tailored to meet the needs of adults and young adults, Recovery Works NW is dedicated to delivering high-quality, individualized care to facilitate lasting recovery.

Recovia
Mesa, AZ

Situated in Mesa, Arizona, Recovia specializes in extensive rehabilitation services aimed at adults and young adults struggling with addiction. The facility offers detox services, tailored substance abuse treatment, as well as targeted support for those facing concurrent mental health issues. Treatment options feature intensive outpatient programs, regular outpatient sessions, and day treatment services. Recovia employs scientifically backed methods like cognitive behavioral therapy and motivational interviewing to foster enduring recovery. Additionally, the center has specific programs designed for individuals who have suffered trauma or deal with both pain and substance abuse challenges. Committed to personalized care, Recovia welcomes clients of all genders with a focus on compassion and high standards.

Recovia
Tucson, AZ

Recovia, situated in Tucson, AZ, offers an extensive array of rehabilitation services catering to both adults and young adults. This center focuses on detoxification, treatment for substance use disorders, and managing co-occurring issues such as severe mental health challenges in adults or significant emotional disturbances in children. Recovia features various therapeutic options including intensive outpatient programs, outpatient day treatment, and partial hospitalization services. The methodologies employed encompass cognitive behavioral therapy, motivational interviewing, and strategies aimed at preventing relapse. With specialized programs designed for individuals who have undergone trauma, those with co-occurring mental health and substance use disorders, and clients facing concurrent pain and substance use issues, Recovia prioritizes personalized care for every individual. Open to clients of all genders, Recovia commits to delivering high-quality, tailored support to facilitate each person's recovery journey.

Recovia
Phoenix, AZ

Situated in Phoenix, AZ, Recovia presents an extensive array of treatment options for detoxification, substance misuse, and overlapping conditions affecting both adults and children. The facility offers a variety of programs including intensive outpatient, outpatient, and day treatment services while employing proven techniques such as cognitive behavioral therapy, motivational interviewing, and strategies for preventing relapse. Recovia focuses on assisting individuals who have undergone trauma, those facing both mental health challenges and substance use issues, and people dealing with pain alongside substance dependencies. Committed to delivering exceptional care, Recovia serves adults and young adults of any gender, ensuring that services are personalized to meet each person's specific requirements.

Recovia
Phoenix, AZ

At Recovia in Phoenix, AZ, adults and young adults facing addiction and mental health issues receive tailored recovery support. The facility provides various levels of care, including intensive outpatient, day treatment, and partial hospitalization programs. Recovia utilizes proven therapeutic methods such as cognitive behavioral therapy, motivational interviewing, and relapse prevention techniques. Specialized programs are available for individuals with trauma backgrounds, co-occurring conditions, and those managing chronic pain. Committed to personalized care for all genders, Recovia offers a nurturing environment for those pursuing lasting wellness.

Red Oak Recovery
Leicester, NC

Situated in Leicester, NC, Red Oak Recovery specializes in treatment for substance use disorders and co-occurring mental health issues specifically for adult males. The center features a range of treatment options, including intensive outpatient, outpatient, and day programs, all employing tried-and-true methods such as cognitive behavioral therapy and anger management techniques. Red Oak Recovery is distinguished by its customized services for active military members, men, and survivors of intimate partner violence. With an emphasis on supporting adults, seniors, and young adults, this facility delivers thorough assistance within a gender-focused setting. For individuals searching for effective solutions in addiction and mental health care, Red Oak Recovery provides a uniquely tailored journey toward healing.

Recovia
Tempe, AZ

Recovia, situated in Tempe, AZ, offers thorough care for those pursuing freedom from substance dependence and concurrent mental health challenges. The facility delivers intensive outpatient, standard outpatient, and day treatment options for adults and young adults, emphasizing cognitive behavioral therapy, motivational interviewing, and strategies for avoiding relapse. Recovia excels in treating trauma, dual diagnoses, and managing pain in conjunction with substance abuse recovery. Catering to both male and female clients, this establishment is committed to providing exceptional, personalized support to guide individuals toward enduring wellness.

Recovery Works NW
Portland, OR

Recovery Works NW, situated in Portland, OR, delivers professional inpatient hospital detoxification. This center specializes in treating adult men and women with dual diagnoses of mental health and substance use challenges, employing techniques like motivational interviewing and trauma-informed counseling. The programs are designed for adults and young adults of all genders, offering personalized care. Known for its thorough methods and high standard of treatment, Recovery Works NW is a leading option for those in the Portland region looking for dedicated and empathetic addiction recovery services.

Recovery Works NW
Portland, OR

Situated in Portland, OR, Recovery Works NW presents a variety of outpatient treatment options for substance use aimed at both adults and young adults. This center excels in addressing both co-occurring mental health and substance use issues, offering services such as brief interventions, cognitive behavioral therapy, and motivational interviewing. Recovery Works NW features specialized programs designed for adult men, adult women, and individuals facing dual diagnoses, emphasizing tailored care for each client. The facility provides outpatient treatments using methadone, buprenorphine, or naltrexone, guaranteeing a holistic approach to recovery. With a strong focus on high-quality care and customized treatment strategies, this center serves as an important asset for individuals in need of effective rehabilitation solutions in the Portland community.

Red Circle Lodge
Hildale, UT

Red Circle Lodge in Hildale, UT, stands as a leading residential treatment center for individuals and young people battling substance use and co-occurring mental health conditions. This facility offers extended-stay programs, featuring distinct pathways for adolescents. Clients receive continuous care around the clock, utilizing proven methods such as 12-step support, emotional regulation techniques, and short-term counseling. Red Circle Lodge accommodates both men and women, employing gender-sensitive treatment strategies. The center is recognized for its dedication to personalized, superior care, making it an excellent destination for those in pursuit of thorough and impactful recovery solutions.

Red Rock Behavioral Health Services

Situated in Kingfisher, OK, Red Rock Behavioral Health Services delivers exceptional treatment for substance use issues affecting both adults and children grappling with severe mental health disorders. The center provides various outpatient services such as methadone/buprenorphine therapy and counseling for substance use disorders. Emphasizing personalized care, they employ techniques like cognitive behavioral therapy and motivational interviewing. Additionally, Red Rock has tailored programs specifically designed for clients involved with the criminal justice system. With an emphasis on care for adults and seniors, the facility serves both male and female clients equally. Rely on Red Rock Behavioral Health Services for thorough and empathetic rehabilitation support.

Red Rock Behavioral Health Services

Red Rock Behavioral Health Services, located in Hobart, OK, delivers outpatient treatment for substance use challenges among adults and children facing significant mental health issues. This center specializes in addressing co-occurring disorders through techniques such as cognitive behavioral therapy, motivational interviewing, and counseling for substance use disorders. Additionally, Red Rock offers outpatient treatment options with methadone, buprenorphine, or naltrexone for clients requiring these services. The facility serves both men and women, including seniors and clients involved with the criminal justice system. Committed to personalized care and utilizing evidence-based practices, this center strives to provide effective rehabilitation services to those in need.

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Phoenix, AZ

Situated in Phoenix, AZ, Recovia delivers a wide range of addiction treatment services aimed at both adults and young adults. The facility emphasizes detoxification and comprehensive substance use rehabilitation, along with targeted support for individuals facing co-occurring mental health challenges. Recovia emphasizes personalized treatment plans, utilizing methods like cognitive behavioral therapy, motivational interviewing, and strategies for preventing relapse. The center also provides specialized services that focus on trauma-responsive care and assistance for clients dealing with both chronic pain and substance use issues. With offerings that include outpatient and intensive outpatient programs, Recovia is committed to providing effective care for all clients pursuing recovery from addiction.

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Red Rock Behavioral Health Services, located in Elk City, OK, specializes in comprehensive treatment for substance use disorders and offers targeted support for those facing both substance use and serious mental health challenges. The center features various programs, including intensive outpatient care, outpatient services, and outpatient options utilizing methadone, buprenorphine, or naltrexone. Emphasizing methods such as cognitive behavioral therapy, motivational interviewing, and counseling for substance use disorders, the center provides personalized treatment plans for adults and seniors, regardless of gender. Notably, Red Rock Behavioral Health Services is dedicated to serving criminal justice and forensic clients, showcasing a strong commitment to delivering high-quality care aimed at promoting sustained recovery and overall health.

Frequently Asked Questions

What is buprenorphine and how does it treat opioid addiction?
Buprenorphine is a partial opioid agonist medication approved by the FDA for treating opioid use disorder. It binds to the same receptors as heroin and fentanyl but produces a much weaker effect, reducing cravings and withdrawal symptoms without causing intense euphoria. Buprenorphine has a ceiling effect, meaning its opioid effects plateau at moderate doses, making it safer than methadone in terms of overdose risk.
What is the difference between Suboxone and Subutex?
Suboxone contains two active ingredients — buprenorphine and naloxone — while Subutex contains only buprenorphine without naloxone. The naloxone in Suboxone is included as an abuse deterrent; it remains inactive when taken sublingually as prescribed but triggers withdrawal if the medication is injected. Subutex is generally reserved for patients who cannot tolerate naloxone, such as pregnant women.
What is a Sublocade injection and how does it work?
Sublocade is a once-monthly injectable form of buprenorphine administered as a subcutaneous injection in the abdominal area. After injection, the medication forms a solid deposit under the skin that slowly releases buprenorphine over the course of a month. This eliminates daily dosing and removes the possibility of missed doses or medication diversion.
What are the common side effects of Suboxone?
Common Suboxone side effects include headache, nausea, constipation, insomnia, sweating, and mouth numbness or pain from sublingual administration. Some patients also experience dizziness, drowsiness, and blurred vision, particularly when starting treatment. Most side effects diminish within the first few weeks as the body adjusts. Patients should report difficulty breathing or signs of allergic reaction immediately.
What happens during Suboxone withdrawal?
Suboxone withdrawal occurs when a patient stops taking the medication abruptly after prolonged use, with symptoms including muscle aches, anxiety, insomnia, nausea, and irritability. A medically supervised taper is strongly recommended, typically reducing the dose by small increments over weeks or months. The risk of opioid relapse is significantly higher during unsupervised discontinuation.
How does Suboxone compare to methadone?
Suboxone and methadone are both effective for opioid use disorder but differ in key ways. Methadone is a full opioid agonist dispensed daily at licensed clinics, while Suboxone is a partial agonist that can be prescribed by qualified physicians and taken at home. Suboxone carries a lower overdose risk due to its ceiling effect and offers greater convenience, though methadone may be more appropriate for patients with severe, long-standing dependence.
How can I find a Suboxone clinic or doctor near me?
The most reliable way to find a Suboxone provider is through SAMHSA's online treatment locator at findtreatment.gov, which allows you to search by location and filter for buprenorphine providers. Many primary care offices, addiction treatment centers, and telehealth platforms now offer Suboxone prescriptions following the elimination of the federal X-waiver requirement in early 2023.
What is Zubsolv and how is it different from Suboxone?
Zubsolv is a brand-name buprenorphine and naloxone sublingual tablet that features a mint flavor and dissolves faster under the tongue than other options. Due to its higher bioavailability, Zubsolv uses different dosing strengths — a Zubsolv 5.7 mg/1.4 mg tablet is considered equivalent to a Suboxone 8 mg/2 mg dose. Patients switching between products should work closely with their prescriber for correct dose conversion.
Does Medicaid cover Suboxone treatment?
Yes — Medicaid covers buprenorphine (including Suboxone, Sublocade, Subutex, Zubsolv, and Brixadi) for opioid use disorder in all 50 states, as required by the SUPPORT Act of 2018. Medicaid is the largest single payer for MAT in the US. Coverage details vary by state — some require prior authorization or limit certain formulations. Many OBOT clinics accept Medicaid directly; telehealth Suboxone providers also bill Medicaid in most states. Bring your Medicaid card to your intake appointment.
Can I get Suboxone through telehealth?
Yes. After the MAT Act of 2023 permanently eliminated the X-waiver requirement, any licensed prescriber can prescribe Suboxone via telehealth in most states. The DEA also extended COVID-era telehealth flexibilities through at least 2025, allowing virtual Suboxone induction without a prior in-person visit. Several specialty platforms — Bicycle Health, Ophelia, Workit Health, Boulder Care — offer Medicaid-accepting telehealth Suboxone treatment. Telehealth has dramatically expanded access in rural and underserved areas with no nearby OBOT physicians.

About Buprenorphine (Suboxone)

Buprenorphine is classified as a partial opioid agonist, meaning it activates opioid receptors in the brain but to a much lesser degree than full agonists such as heroin, fentanyl, or oxycodone. This partial activation suppresses withdrawal symptoms and reduces cravings without producing dangerous respiratory depression or intense euphoria. Buprenorphine also has an unusually high binding affinity for the mu-opioid receptor, effectively blocking other opioids from attaching — providing a protective effect against relapse-related overdose.

How Buprenorphine Works

One of the defining features of buprenorphine is its ceiling effect — after a certain dose threshold, increasing the amount does not produce additional opioid effects. This dramatically reduces the risk of fatal overdose compared to methadone or illicit opioids. The ceiling effect, combined with its long duration of action (24 to 72 hours), makes buprenorphine one of the safest and most effective tools in medication-assisted treatment (MAT). Approved by the FDA in 2002, buprenorphine was a breakthrough because it could be prescribed in outpatient settings rather than requiring daily clinic visits.

Buprenorphine Brand Comparison: Suboxone, Subutex, Sublocade, Zubsolv, Brixadi

Buprenorphine is available under several FDA-approved brand names, each with distinct formulations, dosing schedules, and clinical use cases. The comparison below highlights the key differences:

BrandActive ingredientFormFrequencySettingFDA yearBest for
SuboxoneBuprenorphine + naloxoneSublingual film / tabletDailyOBOT, telehealth, retail pharmacy2002Most prescribed; naloxone deters injection misuse
SubutexBuprenorphine (alone)Sublingual tabletDailyOBOT2002Pregnancy; documented naloxone sensitivity
SublocadeBuprenorphine extended-releaseSubcutaneous injection (ATRIGEL depot)MonthlyClinic-administered2017No daily dosing; eliminates diversion risk
ZubsolvBuprenorphine + naloxoneSublingual tablet (higher bioavailability)DailyOBOT2013Faster dissolution; mint flavor; lower mg/dose
BrixadiBuprenorphine extended-releaseSubcutaneous injectionWeekly or monthlyClinic2023Newer alternative to Sublocade; weekly option for induction

All five medications are Schedule III controlled substances and equivalent in clinical efficacy at appropriate doses. The choice depends on adherence patterns, lifestyle, insurance coverage, and clinical context (e.g., pregnancy, prior injection use, daily-dosing burden). Many patients begin on sublingual Suboxone for stabilization and transition to monthly Sublocade or weekly Brixadi after sustained recovery.

Buprenorphine Side Effects

Common buprenorphine side effects include:

  • Headache and dizziness
  • Nausea and vomiting, especially during induction
  • Constipation and insomnia
  • Excessive sweating
  • Mouth numbness or oral discomfort from sublingual formulations

More serious side effects may include respiratory depression (particularly when combined with benzodiazepines or alcohol), liver problems, and allergic reactions. For most patients, side effects are mild and resolve within one to two weeks. The benefits in preventing relapse and overdose death significantly outweigh the risks.

Buprenorphine Dosage and Induction

Treatment begins with an induction phase where the patient must be in mild to moderate opioid withdrawal. Common induction doses range from 2 mg to 8 mg on the first day, with increases over the following days. Most patients stabilize on 8 mg to 24 mg per day, with 16 mg being the most commonly prescribed dose. Research suggests doses of 16 mg or higher are associated with better retention and outcomes. Dosage should always be adjusted under medical supervision.

Buprenorphine/Naloxone Combination

Many buprenorphine formulations include naloxone as an abuse deterrent. When taken sublingually as directed, naloxone has very low bioavailability and produces no clinical effect. However, if someone attempts to inject the medication, the naloxone component becomes fully active and triggers severe withdrawal. This design discourages injection misuse while having no impact on patients who take the medication correctly. The combination is the standard first-line formulation for opioid addiction treatment.

Suboxone: Sublingual Buprenorphine

Suboxone is the most recognized brand name for buprenorphine-naloxone and is most commonly dispensed as a sublingual film (Suboxone strips) that dissolves under the tongue. Suboxone has transformed opioid treatment by enabling millions of patients to receive effective pharmacotherapy in outpatient settings without the daily clinic visits required by methadone programs.

Suboxone Side Effects

Commonly reported Suboxone side effects include headache, nausea, tongue or mouth irritation, constipation, insomnia, sweating, and decreased libido. The sublingual film can cause irritation or small sores inside the mouth — rotating placement between under the tongue and against the cheek helps minimize this. Patients should not eat, drink, or smoke while the film is dissolving.

Suboxone Strips: Film vs. Tablet

Suboxone strips (sublingual film) have largely replaced the original tablet form. The film dissolves more quickly (two to four minutes), provides more consistent absorption, and is harder to divert due to individual foil packaging. Generic buprenorphine-naloxone tablets are often less expensive and may be preferred for cost reasons. Both are therapeutically equivalent when taken as prescribed.

Suboxone Treatment Programs

Comprehensive Suboxone treatment typically includes three phases:

  • Induction: Initial dosing under medical supervision, requiring the patient to be in early withdrawal
  • Stabilization: Dose adjustment until cravings and withdrawal are minimal, usually one to two months
  • Maintenance: Stable dosing for an extended period — often a year or longer — combined with counseling and behavioral therapy

Evidence consistently shows that longer treatment durations are associated with better outcomes. Most addiction medicine experts recommend a minimum of one to two years of maintenance therapy.

Find a Suboxone Clinic Near You — OBOT & Telehealth Options

Finding a Suboxone clinic has become significantly easier since the federal government eliminated the X-waiver requirement in January 2023, meaning any provider with a standard DEA license can now prescribe Suboxone. Patients can search SAMHSA's treatment locator at findtreatment.gov or use our directory to locate nearby facilities that offer buprenorphine-based treatment.

Suboxone Doctors Near Me

Beyond SAMHSA's locator, many state health departments maintain directories of addiction treatment providers. Telehealth has dramatically expanded access — several platforms now offer virtual Suboxone consultations, which is especially valuable for patients in rural areas. When selecting a provider, look for those offering comprehensive treatment including counseling, not just medication prescriptions.

Suboxone Withdrawal and Tapering

Suboxone withdrawal can include muscle aches, anxiety, insomnia, nausea, sweating, and intense opioid cravings. A gradual, medically supervised taper is recommended — typically reducing the dose by 10 to 25 percent every one to four weeks. Slower tapers over several months produce fewer symptoms and lower relapse rates. There is no medically mandated time limit for Suboxone treatment, and many patients benefit from indefinite maintenance.

Suboxone vs Methadone

Suboxone can be prescribed in office settings and taken at home, carries lower overdose risk due to its ceiling effect, and offers greater scheduling flexibility. Methadone is a full agonist that may be more effective for severe, long-standing dependence but must be dispensed at licensed clinics with daily visits. Neither is inherently superior — the best choice keeps the patient in treatment. Some patients may also benefit from naltrexone, a non-opioid alternative.

Sublocade: Monthly Buprenorphine Injection

Sublocade delivers buprenorphine as a once-monthly subcutaneous injection in the abdominal area using the ATRIGEL delivery system, which forms a solid biodegradable depot that slowly releases medication. Patients must first stabilize on sublingual buprenorphine (8 mg+ daily) for at least seven days. Treatment typically begins with two 300 mg injections, followed by maintenance on 300 mg or 100 mg. Sublocade eliminates concerns about daily adherence, missed doses, and medication diversion.

Sublocade Side Effects

The most common Sublocade side effects are injection-site reactions (pain, itching, redness, or a noticeable lump), nausea, constipation, headache, and fatigue. The injection-site lump is normal and gradually diminishes as medication is absorbed. Patients should avoid rubbing or massaging the site. Elevated liver enzymes may also occur but are usually mild and transient.

Subutex: Buprenorphine Without Naloxone

Subutex was the original brand-name buprenorphine product. While the brand has been discontinued, generic buprenorphine-only tablets remain available. Buprenorphine monotherapy is typically reserved for pregnant patients (to avoid naloxone exposure to the fetus), patients with documented naloxone sensitivity, or sometimes during the induction phase before transitioning to the combination product.

Subutex vs Suboxone

The primary difference is the absence of naloxone in Subutex. Because Subutex lacks the abuse-deterrent naloxone component, it may carry slightly higher diversion risk, and many insurance formularies prioritize the combination as the default. Current clinical guidelines favor buprenorphine-only formulations primarily for pregnancy and naloxone sensitivity.

Zubsolv: Alternative Buprenorphine Brand

Zubsolv is a buprenorphine-naloxone sublingual tablet featuring a mint flavor and faster dissolution (under two minutes). Due to enhanced bioavailability, Zubsolv uses different dose strengths — a 5.7 mg/1.4 mg tablet equals a Suboxone 8 mg/2 mg dose. Zubsolv is available in multiple strengths for flexible dosing during both induction and maintenance.

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Medically Reviewed Updated August 2026

Reviewed by licensed addiction specialists. Information reflects current clinical guidance.

Sources:SAMHSA·NIDA·CDC

Need immediate help? Call SAMHSA: 1-800-662-4357 (24/7, free)