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Updated: July 2026
Sources: SAMHSA, NIDA

Suboxone Clinic Near You: Buprenorphine Treatment for Opioid Addiction

Find a Suboxone clinic near you. Buprenorphine — sold under brand names Suboxone, Sublocade, Subutex, Zubsolv, and Brixadi — is the most-prescribed MAT for opioid use disorder. It is a partial mu-opioid agonist with a ceiling effect that dramatically reduces overdose risk vs. methadone. After the MAT Act of 2023 eliminated the X-waiver requirement, any licensed prescriber can prescribe buprenorphine in office-based settings (OBOT), via telehealth, or at retail pharmacies. Buprenorphine is a Schedule III controlled substance and is covered by Medicaid in all 50 states.

Found 7,145 treatment centers offering buprenorphine (suboxone) across the United States.

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River Source Treatment Center

Situated in Arizona City, AZ, River Source Treatment Center provides extensive rehabilitation programs for both adults and young adults facing challenges with substance abuse and concurrent mental health issues. The center features inpatient detoxification and treatment services that employ methods like 12-step support, anger management therapy, and brief interventions. With tailored programs designed for active military personnel, men, and women, River Source Treatment Center addresses the distinct needs of every client. Its commitment to outstanding care and gender-specific treatment options makes it a preferred destination for individuals looking for personalized and effective addiction recovery solutions.

Rivers Bend PC

Rivers Bend PC, situated in Troy, MI, delivers a wide variety of services aimed at treating addiction. The center specializes in detoxification and offers various substance use treatment options, including intensive outpatient, outpatient, and outpatient detox programs. Employing methods like cognitive behavioral therapy, anger management, and motivational interviewing, the facility supports adult men and women, as well as those who have been victims of sexual abuse. With dedicated programs tailored for both adults and younger clients, Rivers Bend PC is focused on providing personalized care that accommodates all gender identities. Its dedication to high-quality treatment positions it as a reliable option for individuals in need of effective rehabilitation.

Rivers Shore Comprehensive Trt Ctr

River Shore Comprehensive Trt Ctr in Milwaukee, WI, delivers diverse addiction recovery services. They provide detox and comprehensive substance use care via intensive outpatient, standard outpatient, and outpatient detox modalities. Their approach emphasizes anger management, the Matrix Model, and relapse prevention strategies. The center welcomes adult men and women, including pregnant and postpartum individuals, as well as young adults, tailoring programs to each client's unique path to sobriety.

Riverside Recovery of Tampa

Riverside Recovery of Tampa, situated in Tampa, FL, delivers a full spectrum of addiction treatment solutions for adults and young adults. This establishment offers hospital-grade inpatient detoxification and care for substance use disorders, alongside co-occurring mental health challenges. Featuring tailored programs for active duty military personnel, adult men, and women, Riverside Recovery of Tampa addresses a variety of specific requirements. Employing methodologies like 12-step facilitation, anger management, and brief interventions, the center guarantees personalized treatment. Catering to both male and female individuals, this facility emphasizes high-quality care and aids those on their path to recovery.

Riverside San Bernardino County/Indian

Situated in Grand Terrace, CA, Riverside San Bernardino County/Indian serves as a holistic rehabilitation center that delivers outpatient care for both adults and children facing substance use issues alongside mental health challenges. The center features targeted programs specifically designed for adolescents, adult men, and adult women, accommodating a wide array of clients. Their treatment methods encompass 12-step programs, anger management counseling, and brief therapeutic interventions, ensuring that each individual receives customized support. With available outpatient options for methadone/buprenorphine or naltrexone treatment, the facility focuses on the health and recovery of both female and male clients. Riverside San Bernardino County/Indian is committed to offering high-quality support to adults and seniors working towards overcoming substance abuse and mental health difficulties.

River Hills Community Health Center

Situated in Ottumwa, IA, the River Hills Community Health Center provides targeted outpatient services for adults grappling with substance use disorders. The center employs a personalized methodology for treatment, particularly addressing the challenges of concurrent substance abuse and severe mental health issues or emotional challenges. Offering a variety of services such as counseling for substance use disorders and telehealth therapy options, this facility serves both men and women who are in search of effective treatment. Their offerings include outpatient services for methadone/buprenorphine or naltrexone, alongside standard outpatient care. If you or someone close to you needs customized and holistic support for addiction, this center is committed to offering expert care for adults.

Riverside San Bernardino County/Indian

Riverside San Bernardino County/Indian, situated in Thermal, CA, is a dedicated rehabilitation center providing extensive support for individuals of all ages struggling with substance use disorders, particularly those facing co-occurring serious mental health conditions. This center offers flexible outpatient treatment options, including medication-assisted treatment with methadone, buprenorphine, or naltrexone. Their therapeutic approach incorporates proven methods such as 12-step facilitation, anger management, and brief intervention strategies. Riverside San Bernardino County/Indian is equipped to assist adolescents, adult men, adult women, and seniors, ensuring personalized care plans and utilizing evidence-based techniques to foster lasting recovery and overall well-being.

Riverside Treatment Services

Riverside Treatment Services, situated in Rosedale, MD, offers a wide range of outpatient programs designed for substance use rehabilitation. Emphasizing personalized care, the center features outpatient treatments using methadone, buprenorphine, or naltrexone, alongside regular outpatient services. Various therapeutic methods, such as 12-step facilitation, brief intervention, and cognitive behavioral therapy, are also available. This center serves adult men, women, and active military members, welcoming both adults and young adults on their recovery journey. With tailored programs for diverse populations and a dedication to high-quality care, Riverside Treatment Services is a notable resource for individuals seeking to achieve sobriety.

Riverside San Bernardino County

Situated in Temecula, CA, Riverside San Bernardino County specializes in outpatient treatments for individuals grappling with substance abuse and concurrent mental health issues. The center offers a variety of programs designed for both adults and youth, featuring options such as outpatient services with methadone, buprenorphine, or naltrexone. Emphasizing 12-step methods, anger management tactics, and short intervention strategies, it serves clients of all genders and ages, from teenagers to the elderly. Riverside San Bernardino County is particularly notable for its focused treatment initiatives for adult males, adult females, and specific programs aimed at adolescents. The center’s dedication to providing high-quality care positions it as a crucial asset for those in search of thorough and tailored rehabilitation support.

River Valley Medical Wellness

River Valley Medical Wellness, situated in Russellville, AR, provides a full spectrum of addiction recovery support. Their expertise includes detox, substance abuse rehabilitation, and care for dual diagnoses in individuals of all ages. Emphasizing intensive outpatient, general outpatient, and outpatient detox programs, they integrate methods like 12-step support, anger management training, and brief therapeutic interventions. River Valley Medical Wellness supports teens, adult men and women, and older adults, welcoming individuals of any gender. Renowned for its high standards and tailored treatment plans, this center is a leading option for those pursuing effective, individualized recovery.

Riverside County Substance Use Program

Situated in Temecula, CA, the Riverside County Substance Use Program delivers extensive treatment for individuals dealing with substance use challenges, catering to both adults and adolescents. This center features intensive outpatient services, standard outpatient care, and medication-assisted treatment options such as methadone, buprenorphine, or naltrexone. Emphasizing techniques like anger management, brief interventions, and cognitive behavioral therapy, the program serves adult males and females, along with younger clients. Each treatment plan is customized to address the specific needs of the individual, with dedicated pathways for adults and adolescents. With a strong focus on high-quality support, this facility fosters a nurturing atmosphere for those pursuing recovery from substance use disorders.

Riverside Treatment Services

Situated in Edgewood, MD, Riverside Treatment Services provides outpatient care for substance use disorders, featuring options such as methadone, buprenorphine, and naltrexone treatments along with standard outpatient therapy. The center places emphasis on 12-step programs, brief interventions, and cognitive behavioral therapy. It is designed to support active duty military members, as well as adult men and women, offering specialized programs for these demographics. With a commitment to delivering personalized care, Riverside Treatment Services caters to both adults and young adults across genders. If you're looking for a thorough addiction recovery program in a nurturing atmosphere, this center is committed to guiding you towards sustainable recovery.

River Parishes Treatment Center

River Parishes Treatment Center in La Place, LA, provides comprehensive outpatient services for adults battling substance use disorders, particularly those experiencing co-occurring mental health challenges. They also support children with significant emotional difficulties. Their treatment options include medication-assisted treatment with methadone, buprenorphine, or naltrexone, alongside standard outpatient care. Therapeutic interventions such as anger management, brief intervention strategies, and cognitive behavioral therapy are integrated into treatment plans. The center has developed specialized programs tailored for adolescents, adult men, and adult women, emphasizing a personalized approach to recovery. Catering to adults and seniors across genders, River Parishes Treatment Center is dedicated to delivering high-quality, individualized support for long-term healing.

Rivers Edge Behavioral Health

Rivers Edge Behavioral Health, situated in Springfield, ME, delivers targeted addiction recovery services for adults and adolescents. This center is equipped to manage individuals facing dual diagnoses of mental health and substance use issues. Their treatment approach encompasses both long-term and temporary residential stays, adapted to each person's unique requirements. Employing strategies such as cognitive behavioral therapy, anger resolution, and brief intervention, Rivers Edge Behavioral Health guarantees customized, scientifically supported treatment. Dedicated tracks exist for adult men, adult women, and individuals with co-occurring mental health and addiction challenges. The facility welcomes both male and female participants, fostering a nurturing atmosphere for healing and lasting sobriety.

River Hills Community Health Center

River Hills Community Health Center, located in Oskaloosa, IA, specializes in providing outpatient treatment tailored for adults dealing with substance use issues and associated mental health disorders. This facility emphasizes personalized care, offering counseling for substance use disorders and access to telemedicine therapy. Catering to both men and women, River Hills focuses on a unique approach to recovery. Among its services are outpatient treatments using methadone, buprenorphine, or naltrexone. The center is recognized for its exceptional care and dedication to assisting individuals on the path to recovery and improved mental health.

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River City Rehabilitation Center Inc, located in New Braunfels, TX, provides targeted substance abuse treatment services for both adults and young adults. The center offers various outpatient options, such as methadone, buprenorphine, or naltrexone therapies along with standard outpatient care. Emphasizing tailored treatment plans, they employ proven methods including 12-step programs, brief interventions, and cognitive behavioral techniques. River City Rehabilitation Center is particularly attentive to the needs of adult men and women, offering gender-specific programs that foster a nurturing atmosphere for all clients. If you are seeking effective addiction recovery in a caring environment, this facility is an excellent choice for thorough and individualized support.

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River City Rehabilitation Center Inc. in San Antonio, TX, delivers targeted outpatient services for individuals battling substance use disorders. Their comprehensive approach encompasses various treatment modalities such as medication-assisted treatment with methadone, buprenorphine, or naltrexone, standard outpatient care, and support through 12-step facilitation. Employing strategies like brief intervention and cognitive behavioral therapy, the center supports adults, including young adults, and offers gender-specific programming. River City Rehabilitation Center is dedicated to providing effective and individualized care for adults pursuing recovery.

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The Riverside OP Center at Norwood, situated in Norwood, MA, specializes in outpatient services for individuals dealing with substance use disorders and accompanying mental health issues across all age groups. The center employs evidence-based practices such as cognitive behavioral therapy, motivational interviewing, and strategies for preventing relapse to provide personalized treatment that considers each client's specific circumstances. Catering to both adults and youth, the center adopts an inclusive strategy for recovery, ensuring accessibility for all genders. It offers outpatient options including methadone, buprenorphine, and naltrexone treatments, prioritizing high-quality, gender-responsive care to assist clients on their path to recovery.

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Situated in Spokane, Washington, Riverside Recovery Center delivers thorough substance abuse therapy for adults and adolescents. Their specialized services include intensive outpatient programs and outpatient treatment utilizing methadone, buprenorphine, or naltrexone. Riverside Recovery Center employs scientifically validated methods such as brief intervention, cognitive behavioral therapy, and motivational interviewing. The center is particularly equipped to support pregnant and postpartum women with dedicated care. Riverside Recovery Center accepts both men and women, developing personalized treatment strategies for each client. Prioritizing high-quality services and a diverse range of therapeutic approaches, Riverside Recovery Center is committed to aiding individuals in achieving lasting recovery.

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Riverside San Bernardino County, situated in the tranquil environment of San Jacinto, CA, delivers extensive outpatient care for adults grappling with substance use disorders, particularly when accompanied by significant mental health challenges. This center features tailored services designed for young people, adult men, and women, accommodating a broad spectrum of ages from adolescents through seniors. Employing proven therapeutic strategies such as 12-step engagement and anger management techniques, the facility also incorporates short-term interventions to aid individuals in their recovery journey. By emphasizing personalized treatment plans and distinct programs for men and women, Riverside San Bernardino County is committed to providing superior care for those pursuing enduring recovery and overall well-being.

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Riverside San Bernardino County/Indian, situated in Banning, CA, provides comprehensive outpatient addiction treatment for individuals of all ages, including those managing co-occurring severe mental health challenges. The facility delivers dedicated services for active military personnel, teenagers, and adult men, with distinct programs designed for both genders. Their therapeutic interventions encompass 12-step facilitation, anger management techniques, and brief intervention strategies. Committed to elevated standards of care and personalized recovery journeys, this center offers outpatient treatment utilizing methadone, buprenorphine, or naltrexone, alongside general outpatient services, catering to adults and older adults pursuing sobriety.

Frequently Asked Questions

What is buprenorphine and how does it treat opioid addiction?
Buprenorphine is a partial opioid agonist medication approved by the FDA for treating opioid use disorder. It binds to the same receptors as heroin and fentanyl but produces a much weaker effect, reducing cravings and withdrawal symptoms without causing intense euphoria. Buprenorphine has a ceiling effect, meaning its opioid effects plateau at moderate doses, making it safer than methadone in terms of overdose risk.
What is the difference between Suboxone and Subutex?
Suboxone contains two active ingredients — buprenorphine and naloxone — while Subutex contains only buprenorphine without naloxone. The naloxone in Suboxone is included as an abuse deterrent; it remains inactive when taken sublingually as prescribed but triggers withdrawal if the medication is injected. Subutex is generally reserved for patients who cannot tolerate naloxone, such as pregnant women.
What is a Sublocade injection and how does it work?
Sublocade is a once-monthly injectable form of buprenorphine administered as a subcutaneous injection in the abdominal area. After injection, the medication forms a solid deposit under the skin that slowly releases buprenorphine over the course of a month. This eliminates daily dosing and removes the possibility of missed doses or medication diversion.
What are the common side effects of Suboxone?
Common Suboxone side effects include headache, nausea, constipation, insomnia, sweating, and mouth numbness or pain from sublingual administration. Some patients also experience dizziness, drowsiness, and blurred vision, particularly when starting treatment. Most side effects diminish within the first few weeks as the body adjusts. Patients should report difficulty breathing or signs of allergic reaction immediately.
What happens during Suboxone withdrawal?
Suboxone withdrawal occurs when a patient stops taking the medication abruptly after prolonged use, with symptoms including muscle aches, anxiety, insomnia, nausea, and irritability. A medically supervised taper is strongly recommended, typically reducing the dose by small increments over weeks or months. The risk of opioid relapse is significantly higher during unsupervised discontinuation.
How does Suboxone compare to methadone?
Suboxone and methadone are both effective for opioid use disorder but differ in key ways. Methadone is a full opioid agonist dispensed daily at licensed clinics, while Suboxone is a partial agonist that can be prescribed by qualified physicians and taken at home. Suboxone carries a lower overdose risk due to its ceiling effect and offers greater convenience, though methadone may be more appropriate for patients with severe, long-standing dependence.
How can I find a Suboxone clinic or doctor near me?
The most reliable way to find a Suboxone provider is through SAMHSA's online treatment locator at findtreatment.gov, which allows you to search by location and filter for buprenorphine providers. Many primary care offices, addiction treatment centers, and telehealth platforms now offer Suboxone prescriptions following the elimination of the federal X-waiver requirement in early 2023.
What is Zubsolv and how is it different from Suboxone?
Zubsolv is a brand-name buprenorphine and naloxone sublingual tablet that features a mint flavor and dissolves faster under the tongue than other options. Due to its higher bioavailability, Zubsolv uses different dosing strengths — a Zubsolv 5.7 mg/1.4 mg tablet is considered equivalent to a Suboxone 8 mg/2 mg dose. Patients switching between products should work closely with their prescriber for correct dose conversion.
Does Medicaid cover Suboxone treatment?
Yes — Medicaid covers buprenorphine (including Suboxone, Sublocade, Subutex, Zubsolv, and Brixadi) for opioid use disorder in all 50 states, as required by the SUPPORT Act of 2018. Medicaid is the largest single payer for MAT in the US. Coverage details vary by state — some require prior authorization or limit certain formulations. Many OBOT clinics accept Medicaid directly; telehealth Suboxone providers also bill Medicaid in most states. Bring your Medicaid card to your intake appointment.
Can I get Suboxone through telehealth?
Yes. After the MAT Act of 2023 permanently eliminated the X-waiver requirement, any licensed prescriber can prescribe Suboxone via telehealth in most states. The DEA also extended COVID-era telehealth flexibilities through at least 2025, allowing virtual Suboxone induction without a prior in-person visit. Several specialty platforms — Bicycle Health, Ophelia, Workit Health, Boulder Care — offer Medicaid-accepting telehealth Suboxone treatment. Telehealth has dramatically expanded access in rural and underserved areas with no nearby OBOT physicians.

About Buprenorphine (Suboxone)

Buprenorphine is classified as a partial opioid agonist, meaning it activates opioid receptors in the brain but to a much lesser degree than full agonists such as heroin, fentanyl, or oxycodone. This partial activation suppresses withdrawal symptoms and reduces cravings without producing dangerous respiratory depression or intense euphoria. Buprenorphine also has an unusually high binding affinity for the mu-opioid receptor, effectively blocking other opioids from attaching — providing a protective effect against relapse-related overdose.

How Buprenorphine Works

One of the defining features of buprenorphine is its ceiling effect — after a certain dose threshold, increasing the amount does not produce additional opioid effects. This dramatically reduces the risk of fatal overdose compared to methadone or illicit opioids. The ceiling effect, combined with its long duration of action (24 to 72 hours), makes buprenorphine one of the safest and most effective tools in medication-assisted treatment (MAT). Approved by the FDA in 2002, buprenorphine was a breakthrough because it could be prescribed in outpatient settings rather than requiring daily clinic visits.

Buprenorphine Brand Comparison: Suboxone, Subutex, Sublocade, Zubsolv, Brixadi

Buprenorphine is available under several FDA-approved brand names, each with distinct formulations, dosing schedules, and clinical use cases. The comparison below highlights the key differences:

BrandActive ingredientFormFrequencySettingFDA yearBest for
SuboxoneBuprenorphine + naloxoneSublingual film / tabletDailyOBOT, telehealth, retail pharmacy2002Most prescribed; naloxone deters injection misuse
SubutexBuprenorphine (alone)Sublingual tabletDailyOBOT2002Pregnancy; documented naloxone sensitivity
SublocadeBuprenorphine extended-releaseSubcutaneous injection (ATRIGEL depot)MonthlyClinic-administered2017No daily dosing; eliminates diversion risk
ZubsolvBuprenorphine + naloxoneSublingual tablet (higher bioavailability)DailyOBOT2013Faster dissolution; mint flavor; lower mg/dose
BrixadiBuprenorphine extended-releaseSubcutaneous injectionWeekly or monthlyClinic2023Newer alternative to Sublocade; weekly option for induction

All five medications are Schedule III controlled substances and equivalent in clinical efficacy at appropriate doses. The choice depends on adherence patterns, lifestyle, insurance coverage, and clinical context (e.g., pregnancy, prior injection use, daily-dosing burden). Many patients begin on sublingual Suboxone for stabilization and transition to monthly Sublocade or weekly Brixadi after sustained recovery.

Buprenorphine Side Effects

Common buprenorphine side effects include:

  • Headache and dizziness
  • Nausea and vomiting, especially during induction
  • Constipation and insomnia
  • Excessive sweating
  • Mouth numbness or oral discomfort from sublingual formulations

More serious side effects may include respiratory depression (particularly when combined with benzodiazepines or alcohol), liver problems, and allergic reactions. For most patients, side effects are mild and resolve within one to two weeks. The benefits in preventing relapse and overdose death significantly outweigh the risks.

Buprenorphine Dosage and Induction

Treatment begins with an induction phase where the patient must be in mild to moderate opioid withdrawal. Common induction doses range from 2 mg to 8 mg on the first day, with increases over the following days. Most patients stabilize on 8 mg to 24 mg per day, with 16 mg being the most commonly prescribed dose. Research suggests doses of 16 mg or higher are associated with better retention and outcomes. Dosage should always be adjusted under medical supervision.

Buprenorphine/Naloxone Combination

Many buprenorphine formulations include naloxone as an abuse deterrent. When taken sublingually as directed, naloxone has very low bioavailability and produces no clinical effect. However, if someone attempts to inject the medication, the naloxone component becomes fully active and triggers severe withdrawal. This design discourages injection misuse while having no impact on patients who take the medication correctly. The combination is the standard first-line formulation for opioid addiction treatment.

Suboxone: Sublingual Buprenorphine

Suboxone is the most recognized brand name for buprenorphine-naloxone and is most commonly dispensed as a sublingual film (Suboxone strips) that dissolves under the tongue. Suboxone has transformed opioid treatment by enabling millions of patients to receive effective pharmacotherapy in outpatient settings without the daily clinic visits required by methadone programs.

Suboxone Side Effects

Commonly reported Suboxone side effects include headache, nausea, tongue or mouth irritation, constipation, insomnia, sweating, and decreased libido. The sublingual film can cause irritation or small sores inside the mouth — rotating placement between under the tongue and against the cheek helps minimize this. Patients should not eat, drink, or smoke while the film is dissolving.

Suboxone Strips: Film vs. Tablet

Suboxone strips (sublingual film) have largely replaced the original tablet form. The film dissolves more quickly (two to four minutes), provides more consistent absorption, and is harder to divert due to individual foil packaging. Generic buprenorphine-naloxone tablets are often less expensive and may be preferred for cost reasons. Both are therapeutically equivalent when taken as prescribed.

Suboxone Treatment Programs

Comprehensive Suboxone treatment typically includes three phases:

  • Induction: Initial dosing under medical supervision, requiring the patient to be in early withdrawal
  • Stabilization: Dose adjustment until cravings and withdrawal are minimal, usually one to two months
  • Maintenance: Stable dosing for an extended period — often a year or longer — combined with counseling and behavioral therapy

Evidence consistently shows that longer treatment durations are associated with better outcomes. Most addiction medicine experts recommend a minimum of one to two years of maintenance therapy.

Find a Suboxone Clinic Near You — OBOT & Telehealth Options

Finding a Suboxone clinic has become significantly easier since the federal government eliminated the X-waiver requirement in January 2023, meaning any provider with a standard DEA license can now prescribe Suboxone. Patients can search SAMHSA's treatment locator at findtreatment.gov or use our directory to locate nearby facilities that offer buprenorphine-based treatment.

Suboxone Doctors Near Me

Beyond SAMHSA's locator, many state health departments maintain directories of addiction treatment providers. Telehealth has dramatically expanded access — several platforms now offer virtual Suboxone consultations, which is especially valuable for patients in rural areas. When selecting a provider, look for those offering comprehensive treatment including counseling, not just medication prescriptions.

Suboxone Withdrawal and Tapering

Suboxone withdrawal can include muscle aches, anxiety, insomnia, nausea, sweating, and intense opioid cravings. A gradual, medically supervised taper is recommended — typically reducing the dose by 10 to 25 percent every one to four weeks. Slower tapers over several months produce fewer symptoms and lower relapse rates. There is no medically mandated time limit for Suboxone treatment, and many patients benefit from indefinite maintenance.

Suboxone vs Methadone

Suboxone can be prescribed in office settings and taken at home, carries lower overdose risk due to its ceiling effect, and offers greater scheduling flexibility. Methadone is a full agonist that may be more effective for severe, long-standing dependence but must be dispensed at licensed clinics with daily visits. Neither is inherently superior — the best choice keeps the patient in treatment. Some patients may also benefit from naltrexone, a non-opioid alternative.

Sublocade: Monthly Buprenorphine Injection

Sublocade delivers buprenorphine as a once-monthly subcutaneous injection in the abdominal area using the ATRIGEL delivery system, which forms a solid biodegradable depot that slowly releases medication. Patients must first stabilize on sublingual buprenorphine (8 mg+ daily) for at least seven days. Treatment typically begins with two 300 mg injections, followed by maintenance on 300 mg or 100 mg. Sublocade eliminates concerns about daily adherence, missed doses, and medication diversion.

Sublocade Side Effects

The most common Sublocade side effects are injection-site reactions (pain, itching, redness, or a noticeable lump), nausea, constipation, headache, and fatigue. The injection-site lump is normal and gradually diminishes as medication is absorbed. Patients should avoid rubbing or massaging the site. Elevated liver enzymes may also occur but are usually mild and transient.

Subutex: Buprenorphine Without Naloxone

Subutex was the original brand-name buprenorphine product. While the brand has been discontinued, generic buprenorphine-only tablets remain available. Buprenorphine monotherapy is typically reserved for pregnant patients (to avoid naloxone exposure to the fetus), patients with documented naloxone sensitivity, or sometimes during the induction phase before transitioning to the combination product.

Subutex vs Suboxone

The primary difference is the absence of naloxone in Subutex. Because Subutex lacks the abuse-deterrent naloxone component, it may carry slightly higher diversion risk, and many insurance formularies prioritize the combination as the default. Current clinical guidelines favor buprenorphine-only formulations primarily for pregnancy and naloxone sensitivity.

Zubsolv: Alternative Buprenorphine Brand

Zubsolv is a buprenorphine-naloxone sublingual tablet featuring a mint flavor and faster dissolution (under two minutes). Due to enhanced bioavailability, Zubsolv uses different dose strengths — a 5.7 mg/1.4 mg tablet equals a Suboxone 8 mg/2 mg dose. Zubsolv is available in multiple strengths for flexible dosing during both induction and maintenance.

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Medically Reviewed Updated July 2026

Reviewed by licensed addiction specialists. Information reflects current clinical guidance.

Sources:SAMHSA·NIDA·CDC

Need immediate help? Call SAMHSA: 1-800-662-4357 (24/7, free)