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Updated: July 2026
Sources: SAMHSA, NIDA

Suboxone Clinic Near You: Buprenorphine Treatment for Opioid Addiction

Find a Suboxone clinic near you. Buprenorphine — sold under brand names Suboxone, Sublocade, Subutex, Zubsolv, and Brixadi — is the most-prescribed MAT for opioid use disorder. It is a partial mu-opioid agonist with a ceiling effect that dramatically reduces overdose risk vs. methadone. After the MAT Act of 2023 eliminated the X-waiver requirement, any licensed prescriber can prescribe buprenorphine in office-based settings (OBOT), via telehealth, or at retail pharmacies. Buprenorphine is a Schedule III controlled substance and is covered by Medicaid in all 50 states.

Found 7,145 treatment centers offering buprenorphine (suboxone) across the United States.

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Samaritan Medical Center

Samaritan Medical Center in Watertown, NY, provides dedicated rehabilitation for individuals battling substance use disorders, with a focus on also addressing any co-occurring mental health challenges. They offer a range of treatment modalities designed for both adults and younger individuals, including intensive outpatient services, standard outpatient care, and medication-assisted treatment options such as methadone, buprenorphine, and naltrexone. Employing proven methods like cognitive behavioral therapy, motivational interviewing, and brief intervention, the center guides patients toward sustained recovery. Samaritan Medical Center has developed specific programs catering to adolescents, adult men, and women, ensuring inclusive support across different demographics. Their commitment lies in delivering high-quality, personalized care to facilitate enduring recovery for everyone they serve.

Samba Recovery
Peachtree Corners, GA

Samba Recovery in Peachtree Corners, GA, delivers targeted therapies for individuals, both young and adult, grappling with substance abuse and co-occurring mental health challenges. The facility offers various levels of care, including intensive outpatient, outpatient, and day treatment programs. Their therapeutic approach emphasizes strategies like anger management, brief intervention, and cognitive behavioral therapy. Samba Recovery also provides specialized pathways for active duty military personnel, as well as distinct programs for adult men and women. This comprehensive center is dedicated to providing excellent care and support to all individuals pursuing recovery.

San Diego American Indian Health Ctr

San Diego American Indian Health Ctr, located in San Diego, CA, provides outpatient services for those dealing with substance use issues and co-occurring mental health disorders in adults, as well as emotional challenges in children. The center emphasizes strategies such as 12-step programs, brief interventions, and cognitive behavioral therapy, offering specialized care for adult men, adult women, and trauma survivors. Catering to both adults and children/adolescents across all genders, this center is committed to delivering effective treatment in a culturally respectful setting. If you are looking for all-encompassing support that tackles both addiction and mental health difficulties, this facility is here to assist you on your path to recovery.

San Francisco AIDS Foundation

San Francisco AIDS Foundation, situated in San Francisco, CA, provides outpatient services for adults struggling with substance use. Their approach integrates Cognitive Behavioral Therapy, Motivational Interviewing, and Contingency Management. This center is particularly skilled in addressing concurrent substance use disorders and significant mental health concerns in adults, as well as profound emotional challenges in children. They offer specialized programs for adult men and women, including those affected by intimate partner or domestic violence, ensuring high-quality support within an inclusive setting. Committed to assisting adults and young adults in their recovery path, this facility welcomes all clients.

San Francisco General Hospital

Situated in San Francisco, CA, San Francisco General Hospital features a wide array of rehabilitation options. This center is focused on addressing substance use disorders among adults, particularly those facing dual mental health issues. Outpatient services are offered, including treatments with methadone/buprenorphine or naltrexone. The rehabilitation program utilizes proven methods like 12-step facilitation, brief intervention, and cognitive behavioral therapy. Additionally, San Francisco General Hospital caters specifically to individuals living with HIV or AIDS, as well as pregnant or postpartum women, and welcomes both adults and young adults of all genders. Committed to delivering high-quality personalized care, this facility aims to support clients in achieving enduring recovery.

San Luis Valley
Alamosa, CO

Situated in Alamosa, Colorado, the San Luis Valley rehabilitation center delivers extensive treatment for adults grappling with substance use issues alongside significant mental health conditions. Their targeted programs are designed for both adults and seniors, featuring intensive outpatient options as well as outpatient treatments utilizing methadone, buprenorphine, or naltrexone. The center's customized approach incorporates techniques such as anger management, brief interventions, and cognitive behavioral therapy. Additionally, there are specialized initiatives for adolescents, as well as programs tailored for adult men and women, ensuring personalized care for every individual. By providing high-quality treatment for both male and female patients, San Luis Valley stands out as a reliable option for those pursuing effective rehabilitation in a nurturing atmosphere.

Samaritas
Belding, MI

Samaritas in Belding, MI provides extensive recovery support for adults and seniors facing addiction and co-occurring mental health challenges. Their offerings encompass robust outpatient treatment, supervised detox services, and flexible outpatient plans designed to meet individual requirements. The center features distinct programs for adolescents, adult men, and adult women, facilitating highly individualized care. Their therapeutic methods include anger management techniques, targeted brief interventions, and cognitive behavioral therapy, all geared toward achieving sustainable healing. Samaritas is recognized for its dedication to high-quality support and its emphasis on catering to the specific requirements of different genders and age demographics.

Samaritas
Troy, MI

Samaritas, situated in Troy, MI, stands out as a premier rehabilitation center that offers an extensive variety of treatment services for those grappling with substance use disorders. This facility is adept at addressing both substance use issues and significant mental health conditions in adults, alongside severe emotional challenges in children. Emphasizing intensive outpatient and outpatient services, Samaritas employs specialized strategies including anger management, brief intervention, and cognitive behavioral therapy. Their unique programs are designed for individuals across different age groups, including adolescents, adults, and seniors, ensuring personalized treatment approaches for each gender. Samaritas is committed to delivering exceptional care and assistance to those on their journey to overcome addiction.

San Francisco AIDS Foundation

The San Francisco AIDS Foundation, situated in San Francisco, CA, provides outpatient support for individuals grappling with substance use disorders. Their services extend to adults facing co-occurring serious mental health challenges or emotional distress. Employing evidence-based techniques such as cognitive behavioral therapy, motivational interviewing, and contingency management, this establishment delivers targeted interventions for adult men and women, including those who have endured intimate partner violence. Committed to excellence and personalized care, the center serves adult men, women, and young adults looking for holistic addiction recovery within a nurturing setting.

San Luis Valley
Monte Vista, CO

San Luis Valley, situated in Monte Vista, CO, delivers outpatient substance abuse treatment to adults dealing with co-occurring mental health challenges and children experiencing emotional disturbances. The facility employs specialized therapeutic modalities, including anger management, cognitive behavioral therapy, and brief intervention strategies. Personalized treatment plans are offered for adolescents, adult men, and women. San Luis Valley serves adult and senior clients of all genders. Available services encompass outpatient treatment with methadone, buprenorphine, or naltrexone, alongside standard outpatient care. Emphasizing personalized and high-quality care, this center is committed to guiding individuals toward lasting recovery.

San Luis Valley
San Luis, CO

The San Luis Valley rehabilitation center, situated in San Luis, CO, delivers tailored outpatient services for individuals aged adults and children grappling with substance abuse and co-occurring mental health conditions. Their treatment offerings encompass outpatient medication-assisted treatment with methadone, buprenorphine, or naltrexone. Employing therapeutic modalities such as anger management, cognitive behavioral therapy, and brief intervention strategies, the center addresses the needs of those with trauma histories and dual diagnoses. Committed to providing excellent care and employing proven therapeutic methods, the San Luis Valley facility supports individuals across all genders and age groups, from adults to seniors, on their path to healing and sustained wellness.

Samaritas
Grand Rapids, MI

Samaritas, situated in Grand Rapids, MI, provides a wide range of rehabilitation services for adults and seniors facing challenges related to substance use and co-occurring mental health disorders. This center features intensive outpatient programs, general outpatient services, and tailored initiatives for adolescents and those who have experienced trauma. With an emphasis on research-backed methods such as cognitive behavioral therapy and anger management, Samaritas supports both men and women in their recovery journeys. Their outpatient options for methadone/buprenorphine or naltrexone treatment are designed to meet the unique needs of each individual. Samaritas is recognized for its exceptional care and dedication to aiding individuals as they navigate their pathways to recovery.

Samaritas
Charlotte, MI

Samaritas, situated in Charlotte, MI, stands as a premier recovery facility providing a full spectrum of care for adults and seniors facing addiction and co-occurring mental health challenges. They offer robust outpatient detoxification, intensive outpatient programs, and general outpatient services. Their treatment model integrates proven methods like cognitive behavioral therapy, anger management, and brief intervention. Samaritas serves a broad client base, including teenagers, adult males, and adult females, with distinct programs designed for each demographic. Prioritizing high-quality support and personalized treatment strategies, Samaritas is dedicated to guiding individuals toward lasting recovery.

San Diego Freedom Ranch Inc

San Diego Freedom Ranch Inc, located in Campo, CA, offers long-term residential programs focusing on detoxification, substance use treatment, and treating co-occurring substance use with serious mental health issues in adults or serious emotional disturbances in children. The facility provides specialized care for adult men, active duty military personnel, and adolescents. With a focus on 12-step facilitation, anger management, and brief intervention approaches, this center ensures quality and comprehensive care for male clients. Serving adults, seniors, and young adults, San Diego Freedom Ranch Inc is a reliable choice for individuals seeking effective and tailored rehabilitation services.

San Luis Valley
La Jara, CO

Situated in La Jara, Colorado, the San Luis Valley rehabilitation center provides outpatient treatment options for substance use disorders, catering to both adults and children who may also face mental health issues concurrently. This center specializes in various therapeutic approaches, including anger management, cognitive behavioral therapy, and trauma-informed care, offering customized programs designed to assist individuals dealing with substance abuse and mental health problems. Committed to delivering high-quality care, the facility includes outpatient methods such as methadone/buprenorphine and naltrexone treatments, along with standard outpatient services. The San Luis Valley center supports adults and seniors of every gender, establishing itself as a reliable provider of thorough and impactful rehabilitation solutions.

San Luis Valley
Center, CO

Situated in Center, Colorado, the San Luis Valley rehabilitation center provides outpatient services that focus on addressing substance use as well as concurrent mental health issues among both adults and children. Emphasizing techniques such as anger management, cognitive behavioral therapy, and trauma-informed practices, the center creates customized treatment plans for those with varied needs. It offers outpatient options for methadone and buprenorphine, along with standard outpatient support, welcoming clients of all genders, including adults and seniors. The center is dedicated to delivering high-quality care in a nurturing atmosphere for individuals pursuing thorough treatment for substance use and mental health challenges.

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Washington, DC

Samaritan Inns Inc in Washington, DC, delivers extensive addiction recovery services for adult women, older adults, and younger individuals. This facility excels in addressing dual diagnoses, treating substance abuse concurrent with severe mental health conditions in adults and emotional challenges in children. Offering programs of varying lengths, including residential stays available around the clock, Samaritan Inns Inc tailors its therapeutic options to individual requirements. Their treatment methodologies incorporate 12-step guidance, emotional regulation strategies, and brief counseling. The center's specialized services are designed for individuals facing combined mental health and substance use issues, promoting comprehensive well-being. Samaritan Inns Inc is committed to delivering effective, gender-affirming rehabilitation within a caring and encouraging setting.

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Holland, MI

Situated in Holland, Michigan, Samaritas offers a complete spectrum of rehabilitative services, including detox, addiction treatment, and expert support for individuals facing both substance abuse and significant mental health challenges. This center delivers intensive outpatient, standard outpatient, and outpatient detox programs within a nurturing setting. Emphasizing techniques such as anger management, brief intervention, and cognitive behavioral therapy, Samaritas personalizes treatment plans. Dedicated programs are available for teenagers, adult men, and adult women, and the facility serves adults and seniors of all gender identities. Samaritas is committed to providing excellent care with empathy to guide individuals toward lasting recovery.

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San Bernardino County, situated in Rialto, CA, delivers extensive treatment options for substance use for both adults and young adults. This center features outpatient programs that include methadone/buprenorphine or naltrexone therapies, standard outpatient care, brief intervention sessions, the Matrix Model, and motivational interviewing techniques. The facility adopts a personalized approach, providing customized support for every client. With dedicated programs for males and females, San Bernardino County emphasizes high-quality care to assist individuals as they move towards recovery from addiction.

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Situated in Blanding, UT, the San Juan Counseling Center provides targeted outpatient services for adults facing substance abuse as well as concurrent serious mental health challenges, alongside support for emotional difficulties in children. Their extensive offerings include outpatient treatments with methadone/buprenorphine or naltrexone, 12-step programs, anger management sessions, and brief interventions. The center is designed to serve adults and seniors across all genders, focusing on personalized care for trauma survivors and those engaged with the criminal justice system. Committed to delivering quality and customized treatment, the San Juan Counseling Center strives to assist clients in attaining sustainable recovery and enhanced well-being.

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Antonito, CO

Situated in Antonito, CO, the San Luis Valley rehabilitation center provides tailored outpatient services for individuals dealing with substance use disorders and accompanying mental health challenges, catering to both adults and children. Emphasizing approaches such as anger management, cognitive behavioral therapy, and trauma-informed practices, the center designs customized programs for clients with intricate requirements. Welcoming adults and seniors of all genders, it fosters a nurturing and secure atmosphere for recovery and healing. The facility offers outpatient treatments with methadone, buprenorphine, or naltrexone, alongside standard outpatient services, demonstrating a dedication to high-quality, evidence-based care to promote enduring wellness.

Frequently Asked Questions

What is buprenorphine and how does it treat opioid addiction?
Buprenorphine is a partial opioid agonist medication approved by the FDA for treating opioid use disorder. It binds to the same receptors as heroin and fentanyl but produces a much weaker effect, reducing cravings and withdrawal symptoms without causing intense euphoria. Buprenorphine has a ceiling effect, meaning its opioid effects plateau at moderate doses, making it safer than methadone in terms of overdose risk.
What is the difference between Suboxone and Subutex?
Suboxone contains two active ingredients — buprenorphine and naloxone — while Subutex contains only buprenorphine without naloxone. The naloxone in Suboxone is included as an abuse deterrent; it remains inactive when taken sublingually as prescribed but triggers withdrawal if the medication is injected. Subutex is generally reserved for patients who cannot tolerate naloxone, such as pregnant women.
What is a Sublocade injection and how does it work?
Sublocade is a once-monthly injectable form of buprenorphine administered as a subcutaneous injection in the abdominal area. After injection, the medication forms a solid deposit under the skin that slowly releases buprenorphine over the course of a month. This eliminates daily dosing and removes the possibility of missed doses or medication diversion.
What are the common side effects of Suboxone?
Common Suboxone side effects include headache, nausea, constipation, insomnia, sweating, and mouth numbness or pain from sublingual administration. Some patients also experience dizziness, drowsiness, and blurred vision, particularly when starting treatment. Most side effects diminish within the first few weeks as the body adjusts. Patients should report difficulty breathing or signs of allergic reaction immediately.
What happens during Suboxone withdrawal?
Suboxone withdrawal occurs when a patient stops taking the medication abruptly after prolonged use, with symptoms including muscle aches, anxiety, insomnia, nausea, and irritability. A medically supervised taper is strongly recommended, typically reducing the dose by small increments over weeks or months. The risk of opioid relapse is significantly higher during unsupervised discontinuation.
How does Suboxone compare to methadone?
Suboxone and methadone are both effective for opioid use disorder but differ in key ways. Methadone is a full opioid agonist dispensed daily at licensed clinics, while Suboxone is a partial agonist that can be prescribed by qualified physicians and taken at home. Suboxone carries a lower overdose risk due to its ceiling effect and offers greater convenience, though methadone may be more appropriate for patients with severe, long-standing dependence.
How can I find a Suboxone clinic or doctor near me?
The most reliable way to find a Suboxone provider is through SAMHSA's online treatment locator at findtreatment.gov, which allows you to search by location and filter for buprenorphine providers. Many primary care offices, addiction treatment centers, and telehealth platforms now offer Suboxone prescriptions following the elimination of the federal X-waiver requirement in early 2023.
What is Zubsolv and how is it different from Suboxone?
Zubsolv is a brand-name buprenorphine and naloxone sublingual tablet that features a mint flavor and dissolves faster under the tongue than other options. Due to its higher bioavailability, Zubsolv uses different dosing strengths — a Zubsolv 5.7 mg/1.4 mg tablet is considered equivalent to a Suboxone 8 mg/2 mg dose. Patients switching between products should work closely with their prescriber for correct dose conversion.
Does Medicaid cover Suboxone treatment?
Yes — Medicaid covers buprenorphine (including Suboxone, Sublocade, Subutex, Zubsolv, and Brixadi) for opioid use disorder in all 50 states, as required by the SUPPORT Act of 2018. Medicaid is the largest single payer for MAT in the US. Coverage details vary by state — some require prior authorization or limit certain formulations. Many OBOT clinics accept Medicaid directly; telehealth Suboxone providers also bill Medicaid in most states. Bring your Medicaid card to your intake appointment.
Can I get Suboxone through telehealth?
Yes. After the MAT Act of 2023 permanently eliminated the X-waiver requirement, any licensed prescriber can prescribe Suboxone via telehealth in most states. The DEA also extended COVID-era telehealth flexibilities through at least 2025, allowing virtual Suboxone induction without a prior in-person visit. Several specialty platforms — Bicycle Health, Ophelia, Workit Health, Boulder Care — offer Medicaid-accepting telehealth Suboxone treatment. Telehealth has dramatically expanded access in rural and underserved areas with no nearby OBOT physicians.

About Buprenorphine (Suboxone)

Buprenorphine is classified as a partial opioid agonist, meaning it activates opioid receptors in the brain but to a much lesser degree than full agonists such as heroin, fentanyl, or oxycodone. This partial activation suppresses withdrawal symptoms and reduces cravings without producing dangerous respiratory depression or intense euphoria. Buprenorphine also has an unusually high binding affinity for the mu-opioid receptor, effectively blocking other opioids from attaching — providing a protective effect against relapse-related overdose.

How Buprenorphine Works

One of the defining features of buprenorphine is its ceiling effect — after a certain dose threshold, increasing the amount does not produce additional opioid effects. This dramatically reduces the risk of fatal overdose compared to methadone or illicit opioids. The ceiling effect, combined with its long duration of action (24 to 72 hours), makes buprenorphine one of the safest and most effective tools in medication-assisted treatment (MAT). Approved by the FDA in 2002, buprenorphine was a breakthrough because it could be prescribed in outpatient settings rather than requiring daily clinic visits.

Buprenorphine Brand Comparison: Suboxone, Subutex, Sublocade, Zubsolv, Brixadi

Buprenorphine is available under several FDA-approved brand names, each with distinct formulations, dosing schedules, and clinical use cases. The comparison below highlights the key differences:

BrandActive ingredientFormFrequencySettingFDA yearBest for
SuboxoneBuprenorphine + naloxoneSublingual film / tabletDailyOBOT, telehealth, retail pharmacy2002Most prescribed; naloxone deters injection misuse
SubutexBuprenorphine (alone)Sublingual tabletDailyOBOT2002Pregnancy; documented naloxone sensitivity
SublocadeBuprenorphine extended-releaseSubcutaneous injection (ATRIGEL depot)MonthlyClinic-administered2017No daily dosing; eliminates diversion risk
ZubsolvBuprenorphine + naloxoneSublingual tablet (higher bioavailability)DailyOBOT2013Faster dissolution; mint flavor; lower mg/dose
BrixadiBuprenorphine extended-releaseSubcutaneous injectionWeekly or monthlyClinic2023Newer alternative to Sublocade; weekly option for induction

All five medications are Schedule III controlled substances and equivalent in clinical efficacy at appropriate doses. The choice depends on adherence patterns, lifestyle, insurance coverage, and clinical context (e.g., pregnancy, prior injection use, daily-dosing burden). Many patients begin on sublingual Suboxone for stabilization and transition to monthly Sublocade or weekly Brixadi after sustained recovery.

Buprenorphine Side Effects

Common buprenorphine side effects include:

  • Headache and dizziness
  • Nausea and vomiting, especially during induction
  • Constipation and insomnia
  • Excessive sweating
  • Mouth numbness or oral discomfort from sublingual formulations

More serious side effects may include respiratory depression (particularly when combined with benzodiazepines or alcohol), liver problems, and allergic reactions. For most patients, side effects are mild and resolve within one to two weeks. The benefits in preventing relapse and overdose death significantly outweigh the risks.

Buprenorphine Dosage and Induction

Treatment begins with an induction phase where the patient must be in mild to moderate opioid withdrawal. Common induction doses range from 2 mg to 8 mg on the first day, with increases over the following days. Most patients stabilize on 8 mg to 24 mg per day, with 16 mg being the most commonly prescribed dose. Research suggests doses of 16 mg or higher are associated with better retention and outcomes. Dosage should always be adjusted under medical supervision.

Buprenorphine/Naloxone Combination

Many buprenorphine formulations include naloxone as an abuse deterrent. When taken sublingually as directed, naloxone has very low bioavailability and produces no clinical effect. However, if someone attempts to inject the medication, the naloxone component becomes fully active and triggers severe withdrawal. This design discourages injection misuse while having no impact on patients who take the medication correctly. The combination is the standard first-line formulation for opioid addiction treatment.

Suboxone: Sublingual Buprenorphine

Suboxone is the most recognized brand name for buprenorphine-naloxone and is most commonly dispensed as a sublingual film (Suboxone strips) that dissolves under the tongue. Suboxone has transformed opioid treatment by enabling millions of patients to receive effective pharmacotherapy in outpatient settings without the daily clinic visits required by methadone programs.

Suboxone Side Effects

Commonly reported Suboxone side effects include headache, nausea, tongue or mouth irritation, constipation, insomnia, sweating, and decreased libido. The sublingual film can cause irritation or small sores inside the mouth — rotating placement between under the tongue and against the cheek helps minimize this. Patients should not eat, drink, or smoke while the film is dissolving.

Suboxone Strips: Film vs. Tablet

Suboxone strips (sublingual film) have largely replaced the original tablet form. The film dissolves more quickly (two to four minutes), provides more consistent absorption, and is harder to divert due to individual foil packaging. Generic buprenorphine-naloxone tablets are often less expensive and may be preferred for cost reasons. Both are therapeutically equivalent when taken as prescribed.

Suboxone Treatment Programs

Comprehensive Suboxone treatment typically includes three phases:

  • Induction: Initial dosing under medical supervision, requiring the patient to be in early withdrawal
  • Stabilization: Dose adjustment until cravings and withdrawal are minimal, usually one to two months
  • Maintenance: Stable dosing for an extended period — often a year or longer — combined with counseling and behavioral therapy

Evidence consistently shows that longer treatment durations are associated with better outcomes. Most addiction medicine experts recommend a minimum of one to two years of maintenance therapy.

Find a Suboxone Clinic Near You — OBOT & Telehealth Options

Finding a Suboxone clinic has become significantly easier since the federal government eliminated the X-waiver requirement in January 2023, meaning any provider with a standard DEA license can now prescribe Suboxone. Patients can search SAMHSA's treatment locator at findtreatment.gov or use our directory to locate nearby facilities that offer buprenorphine-based treatment.

Suboxone Doctors Near Me

Beyond SAMHSA's locator, many state health departments maintain directories of addiction treatment providers. Telehealth has dramatically expanded access — several platforms now offer virtual Suboxone consultations, which is especially valuable for patients in rural areas. When selecting a provider, look for those offering comprehensive treatment including counseling, not just medication prescriptions.

Suboxone Withdrawal and Tapering

Suboxone withdrawal can include muscle aches, anxiety, insomnia, nausea, sweating, and intense opioid cravings. A gradual, medically supervised taper is recommended — typically reducing the dose by 10 to 25 percent every one to four weeks. Slower tapers over several months produce fewer symptoms and lower relapse rates. There is no medically mandated time limit for Suboxone treatment, and many patients benefit from indefinite maintenance.

Suboxone vs Methadone

Suboxone can be prescribed in office settings and taken at home, carries lower overdose risk due to its ceiling effect, and offers greater scheduling flexibility. Methadone is a full agonist that may be more effective for severe, long-standing dependence but must be dispensed at licensed clinics with daily visits. Neither is inherently superior — the best choice keeps the patient in treatment. Some patients may also benefit from naltrexone, a non-opioid alternative.

Sublocade: Monthly Buprenorphine Injection

Sublocade delivers buprenorphine as a once-monthly subcutaneous injection in the abdominal area using the ATRIGEL delivery system, which forms a solid biodegradable depot that slowly releases medication. Patients must first stabilize on sublingual buprenorphine (8 mg+ daily) for at least seven days. Treatment typically begins with two 300 mg injections, followed by maintenance on 300 mg or 100 mg. Sublocade eliminates concerns about daily adherence, missed doses, and medication diversion.

Sublocade Side Effects

The most common Sublocade side effects are injection-site reactions (pain, itching, redness, or a noticeable lump), nausea, constipation, headache, and fatigue. The injection-site lump is normal and gradually diminishes as medication is absorbed. Patients should avoid rubbing or massaging the site. Elevated liver enzymes may also occur but are usually mild and transient.

Subutex: Buprenorphine Without Naloxone

Subutex was the original brand-name buprenorphine product. While the brand has been discontinued, generic buprenorphine-only tablets remain available. Buprenorphine monotherapy is typically reserved for pregnant patients (to avoid naloxone exposure to the fetus), patients with documented naloxone sensitivity, or sometimes during the induction phase before transitioning to the combination product.

Subutex vs Suboxone

The primary difference is the absence of naloxone in Subutex. Because Subutex lacks the abuse-deterrent naloxone component, it may carry slightly higher diversion risk, and many insurance formularies prioritize the combination as the default. Current clinical guidelines favor buprenorphine-only formulations primarily for pregnancy and naloxone sensitivity.

Zubsolv: Alternative Buprenorphine Brand

Zubsolv is a buprenorphine-naloxone sublingual tablet featuring a mint flavor and faster dissolution (under two minutes). Due to enhanced bioavailability, Zubsolv uses different dose strengths — a 5.7 mg/1.4 mg tablet equals a Suboxone 8 mg/2 mg dose. Zubsolv is available in multiple strengths for flexible dosing during both induction and maintenance.

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Medically Reviewed Updated July 2026

Reviewed by licensed addiction specialists. Information reflects current clinical guidance.

Sources:SAMHSA·NIDA·CDC

Need immediate help? Call SAMHSA: 1-800-662-4357 (24/7, free)