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Medically Reviewed Content
Updated: July 2026
Sources: SAMHSA, NIDA

Suboxone Clinic Near You: Buprenorphine Treatment for Opioid Addiction

Find a Suboxone clinic near you. Buprenorphine — sold under brand names Suboxone, Sublocade, Subutex, Zubsolv, and Brixadi — is the most-prescribed MAT for opioid use disorder. It is a partial mu-opioid agonist with a ceiling effect that dramatically reduces overdose risk vs. methadone. After the MAT Act of 2023 eliminated the X-waiver requirement, any licensed prescriber can prescribe buprenorphine in office-based settings (OBOT), via telehealth, or at retail pharmacies. Buprenorphine is a Schedule III controlled substance and is covered by Medicaid in all 50 states.

Found 7,145 treatment centers offering buprenorphine (suboxone) across the United States.

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Sierra Tucson
Tucson, AZ

Sierra Tucson, situated in Tucson, Arizona, provides extensive support for adults and young adults dealing with substance use issues alongside mental health challenges. The center features inpatient detox services and various treatment programs, including targeted assistance for individuals with past trauma or experiences of sexual abuse. With an emphasis on 12-step programs, anger management, and short-term interventions, Sierra Tucson serves both men and women, including active military members. Renowned for its exceptional care and personalized treatment plans, this center stands out as a leading option for individuals in need of empathetic rehabilitation solutions.

Signature Health Inc

Located in Ashtabula, OH, Signature Health Inc provides a wide variety of rehabilitation services. The center focuses on detoxification and treatment for substance use disorders, while also addressing the needs of those with concurrent serious mental health challenges or emotional issues. Treatment options are available in formats such as intensive outpatient, outpatient, and partial hospitalization, with a strong emphasis on evidence-based methods like cognitive behavioral therapy and motivational interviewing. What distinguishes Signature Health Inc is its commitment to creating customized programs for each individual. Catering to adults and seniors of any gender, the center prioritizes delivering top-notch care with a strong emphasis on individualized treatment strategies to facilitate effective recovery.

Signature Health Inc
Willoughby, OH

Located in Willoughby, OH, Signature Health Inc provides a wide array of services for adults and seniors struggling with addiction. Their offerings encompass detox services, treatment for substance use disorders, and support for individuals facing both substance use and significant mental health challenges in adults or severe emotional issues in children. The center utilizes various treatment modalities, including intensive outpatient, outpatient, and day treatment programs, ensuring that care is customized to meet individual needs through methods such as cognitive behavioral therapy and motivational interviewing. Signature Health Inc is dedicated to delivering quality care tailored for both male and female patients, making it an excellent option for those in search of effective and personalized treatment for addiction.

Signature Health Inc

Situated in Beachwood, OH, Signature Health Inc delivers extensive services for addiction recovery aimed at adults and seniors. This center specializes in detoxification, treatment for substance use disorders, and offers tailored assistance for individuals facing concurrent substance use and significant mental health challenges, as well as serious emotional disturbances in children. The program encompasses options such as intensive outpatient care, standard outpatient services, and day treatment. Emphasizing techniques like brief intervention, cognitive-behavioral therapy, and motivational interviewing, Signature Health Inc customizes treatment plans to meet the unique needs of each client. The facility is recognized for its personalized approach, providing high-quality care for both men and women in their journey to overcome addiction.

Silicon Valley Recovery

Silicon Valley Recovery, located in San Jose, CA, provides a wide range of addiction treatment options for both adults and young adults. This facility features long-term residential programs, detoxification services, and around-the-clock residential assistance. Emphasizing 12-step methodologies, anger management strategies, and brief intervention techniques, the center customizes its treatment plans to meet the unique requirements of each individual. There are specialized programs designed for both adult men and women, fostering a nurturing and inclusive atmosphere. The committed team at Silicon Valley Recovery delivers high-quality support for clients of all genders, positioning it as an exceptional option for those in need of effective substance abuse treatment and detoxification in the Silicon Valley region.

Silver Linings Recovery Center

Silver Linings Recovery Center, situated in Langhorne, PA, provides extensive care for individuals struggling with substance use. The center focuses on addressing co-occurring mental health challenges in adults and emotional difficulties in children alongside substance dependency. Their therapeutic offerings encompass intensive outpatient, outpatient, and day treatment programs, all delivered with personalized support. Utilizing methods like 12-step facilitation, anger management, and brief interventions, Silver Linings Recovery Center distinguishes itself through its dedicated programs for those with dual diagnoses of mental and substance use disorders, serving both men and women with an emphasis on superior care and overall well-being.

Silver Pines Treatment Center

Silver Pines Treatment Center, situated in Mahanoy City, PA, delivers extensive support for those in need of detox and addiction treatment. Services include round-the-clock hospital inpatient detoxification and residential detoxification. Employing proven methods like 12-step facilitation, cognitive behavioral therapy, and motivational interviewing, this establishment serves active military, adult men and women, and individuals across different age demographics, including young adults. By offering individualized programs designed for specific gender and age considerations, Silver Pines Treatment Center guarantees top-tier assistance and care for everyone pursuing sobriety.

Silver Ridge
Mills River, NC

Nestled in Mills River, NC, Silver Ridge provides a complete suite of substance abuse recovery services for adults and adolescents. The facility excels in addressing dual diagnoses, offering intensive outpatient care, extended residential stays, and standard outpatient programs. Employing proven methods such as cognitive behavioral therapy and anger management techniques, Silver Ridge customizes recovery journeys to suit each person's unique requirements. Featuring dedicated programs for active military members, adult males, and adult females, the center cultivates a nurturing atmosphere for everyone. Committed to superior care centered on comprehensive well-being, Silver Ridge stands as a reliable choice for individuals pursuing effective and empathetic addiction recovery.

Silver Sands Recovery

Silver Sands Recovery in Prescott, AZ, provides thorough addiction treatment and expert support for individuals facing dual diagnoses of mental health conditions. This center offers structured outpatient services, incorporating 12-step principles, cognitive behavioral strategies, and techniques for managing anger. Emphasizing supportive transitional housing and sober living options, Silver Sands Recovery serves adult men and women, along with young adults. Their specialized care for co-occurring disorders guarantees personalized treatment plans. Opt for Silver Sands Recovery for effective, gender-tailored care in a peaceful Arizona location.

Shoreline Family Healthcare

Shoreline Family Healthcare in Branford, CT, provides outpatient services for individuals, encompassing adults and children who are dealing with substance use disorders alongside serious mental health conditions. The facility features targeted programs designed for active military personnel, teenagers, and adult males. Their therapeutic interventions include strategies for managing anger, brief counseling, and cognitive behavioral therapy. Patients can access medication-assisted treatment using methadone, buprenorphine, or naltrexone, in addition to standard outpatient care. Catering to adults and seniors regardless of gender, this center is dedicated to delivering effective rehabilitation that is personalized to each person's specific requirements, cultivating a nurturing setting conducive to healing and sustained recovery.

Silver Hill Hospital Inc

Silver Hill Hospital Inc, located in New Canaan, CT, offers dedicated inpatient services aimed at detoxification, treatment for substance use, and addressing co-occurring mental health issues for both adults and children. The center emphasizes 12-step approaches, anger management, and short-term interventions, providing thorough care for those facing trauma, substance use challenges, and mental health concerns. With specialized programs for teenagers and individuals with dual diagnoses, they ensure that treatment is personalized. Silver Hill Hospital Inc is committed to delivering effective, gender-sensitive care that promotes recovery and holistic well-being for all clients, regardless of age or gender.

Sierra Vista Hospital
Sacramento, CA

Sierra Vista Hospital in Sacramento, CA, delivers a complete spectrum of addiction recovery care for individuals of all ages. This institution features hospital-based inpatient detoxification and therapeutic programs designed to address substance use disorders, even those complicated by co-occurring mental health conditions. Employing scientifically validated methodologies such as 12-step facilitation, cognitive behavioral therapy, and specialized substance use disorder counseling, Sierra Vista Hospital crafts personalized treatment plans. Distinct programs are available for active duty military members, teenagers, and adult women. Prioritizing high-quality care and specialized services for various demographics, Sierra Vista Hospital is committed to guiding patients toward enduring sobriety.

Shoreline Behavioral Health Services

Situated in Conway, SC, Shoreline Behavioral Health Services delivers extensive treatment for substance use disorders, catering to adults, adolescents, and seniors. This facility offers a range of services including intensive outpatient programs, outpatient treatment, and medication-assisted therapies with methadone, buprenorphine, or naltrexone. Shoreline emphasizes key therapeutic approaches such as anger management, brief interventions, and cognitive behavioral therapy, supporting both male and female clients. Noteworthy is Shoreline Behavioral Health Services’ commitment to specialized programs designed for adolescents as well as adult men and women, enabling customized care with a focus on the unique needs of each gender to foster effective recovery from addiction.

Silver Maple Recovery

Situated in Lorain, OH, Silver Maple Recovery stands out as a premier rehabilitation center dedicated to providing hospital inpatient detox and treatment services specifically for adult males. The facility emphasizes 12-step support, anger management strategies, and short-term intervention methods to assist clients dealing with both mental health issues and substance use disorders, including those who have faced trauma. Silver Maple Recovery serves a diverse demographic of adult men, ranging from young adults to seniors. With a strong emphasis on personalized care and high-quality treatment, this center fosters a nurturing atmosphere for individuals looking to address their substance use difficulties.

Sigma Health Services

Sigma Health Services, located in Raleigh, NC, delivers extensive rehabilitation programs aimed at addressing substance abuse and concurrent mental health disorders for both adults and youth. The center features multiple treatment options, including intensive outpatient programs and day treatment sessions, along with offerings such as 12-step facilitation, anger management support, and brief intervention strategies. There are specialized programs available for active military personnel, teenagers, and men. Sigma Health Services is committed to serving individuals of all genders, prioritizing personalized care and scientifically supported methods to provide effective treatment for those pursuing recovery from addiction and mental health difficulties.

Silver Creek Clinic

Situated in Orem, UT, Silver Creek Clinic provides a wide range of outpatient rehabilitation services with a focus on detoxification and the treatment of substance use disorders. The center employs various methods, including anger management, cognitive behavioral therapy, and motivational incentives, to support adult men and women, including individuals living with HIV or AIDS. Designed to meet the diverse needs of adults and young adults across genders, Silver Creek Clinic fosters a nurturing environment for those on the path to recovery. The center offers personalized outpatient detoxification and treatment options featuring methadone, buprenorphine, or naltrexone. Opt for Silver Creek Clinic for high-quality, evidence-based care in a friendly atmosphere.

Shreveport Behavioral Health Clinic

Situated in Shreveport, LA, the Shreveport Behavioral Health Clinic specializes in addressing substance use disorders along with associated severe mental health challenges in adults. The center offers a range of treatment options including intensive outpatient programs, general outpatient services, as well as methadone or buprenorphine/naltrexone treatments on an outpatient basis. Emphasizing methods like 12-step facilitation, cognitive behavioral therapy, and the Matrix Model, the clinic customizes its approach to suit each individual's requirements. Additionally, there are dedicated programs for active military personnel, adolescents, and adult males. The clinic provides comprehensive care for adults and seniors across all genders, ensuring effective treatment through gender-sensitive programs and individualized strategies.

Sibus Treatment Services LLC

Situated in Elkridge, MD, Sibus Treatment Services LLC specializes in outpatient programs for substance use treatment, prioritizing high-quality care. This center offers outpatient services featuring methadone, buprenorphine, or naltrexone, in addition to counseling for substance use disorders and telehealth therapy. Sibus Treatment Services LLC serves both adult men and women, including those who have faced sexual abuse. With tailored programs for adults and young adults of all genders, this facility fosters a nurturing atmosphere for individuals on their journey to recovery from addiction.

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Shiloh Psychological Consulting PLLC, located in New York, NY, specializes in the treatment of substance use disorders and co-occurring mental health issues for both adults and children. The center offers a range of programs, including intensive outpatient, outpatient, and regular outpatient care. Emphasizing approaches like 12-step facilitation, anger management, and brief interventions, they create customized treatment plans for individuals with varying needs. The center features specialized programs designed for active duty military personnel, adult males, and individuals who have experienced intimate partner violence. With a commitment to providing exceptional, person-centered rehabilitation services, Shiloh Psychological Consulting PLLC supports adults and young adults of all genders in achieving sustained recovery.

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Shoreline Recovery Center located in Encinitas, CA, specializes in treating adult men who are facing substance use challenges alongside mental health issues. This center offers various treatment programs, including intensive outpatient, outpatient, and day treatment, utilizing proven methodologies such as 12-step facilitation and strategies for managing anger. Customized programs are designed for individuals who have faced traumatic experiences. By prioritizing high-quality care, the center serves a diverse population including adults, seniors, and young adults, ensuring a well-rounded recovery process. If you or someone you know is looking for empathetic and effective support for substance use problems, Shoreline Recovery Center is committed to guiding you on the path to recovery.

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Sierra Transformation Center in Las Vegas, NV, provides focused outpatient services for adults and youth dealing with addiction and co-occurring mental health conditions. Employing evidence-based methods such as 12-step guidance, cognitive behavioral strategies, and short-term counseling, the center delivers personalized support. Their programs are designed for active military personnel, teenagers, and adult men. Sierra Transformation Center is committed to delivering high-standard care for both men and women seeking thorough recovery assistance in a nurturing setting. They offer individualized approaches for outpatient detox and maintenance treatments like methadone and buprenorphine, aiming for sustained healing.

Frequently Asked Questions

What is buprenorphine and how does it treat opioid addiction?
Buprenorphine is a partial opioid agonist medication approved by the FDA for treating opioid use disorder. It binds to the same receptors as heroin and fentanyl but produces a much weaker effect, reducing cravings and withdrawal symptoms without causing intense euphoria. Buprenorphine has a ceiling effect, meaning its opioid effects plateau at moderate doses, making it safer than methadone in terms of overdose risk.
What is the difference between Suboxone and Subutex?
Suboxone contains two active ingredients — buprenorphine and naloxone — while Subutex contains only buprenorphine without naloxone. The naloxone in Suboxone is included as an abuse deterrent; it remains inactive when taken sublingually as prescribed but triggers withdrawal if the medication is injected. Subutex is generally reserved for patients who cannot tolerate naloxone, such as pregnant women.
What is a Sublocade injection and how does it work?
Sublocade is a once-monthly injectable form of buprenorphine administered as a subcutaneous injection in the abdominal area. After injection, the medication forms a solid deposit under the skin that slowly releases buprenorphine over the course of a month. This eliminates daily dosing and removes the possibility of missed doses or medication diversion.
What are the common side effects of Suboxone?
Common Suboxone side effects include headache, nausea, constipation, insomnia, sweating, and mouth numbness or pain from sublingual administration. Some patients also experience dizziness, drowsiness, and blurred vision, particularly when starting treatment. Most side effects diminish within the first few weeks as the body adjusts. Patients should report difficulty breathing or signs of allergic reaction immediately.
What happens during Suboxone withdrawal?
Suboxone withdrawal occurs when a patient stops taking the medication abruptly after prolonged use, with symptoms including muscle aches, anxiety, insomnia, nausea, and irritability. A medically supervised taper is strongly recommended, typically reducing the dose by small increments over weeks or months. The risk of opioid relapse is significantly higher during unsupervised discontinuation.
How does Suboxone compare to methadone?
Suboxone and methadone are both effective for opioid use disorder but differ in key ways. Methadone is a full opioid agonist dispensed daily at licensed clinics, while Suboxone is a partial agonist that can be prescribed by qualified physicians and taken at home. Suboxone carries a lower overdose risk due to its ceiling effect and offers greater convenience, though methadone may be more appropriate for patients with severe, long-standing dependence.
How can I find a Suboxone clinic or doctor near me?
The most reliable way to find a Suboxone provider is through SAMHSA's online treatment locator at findtreatment.gov, which allows you to search by location and filter for buprenorphine providers. Many primary care offices, addiction treatment centers, and telehealth platforms now offer Suboxone prescriptions following the elimination of the federal X-waiver requirement in early 2023.
What is Zubsolv and how is it different from Suboxone?
Zubsolv is a brand-name buprenorphine and naloxone sublingual tablet that features a mint flavor and dissolves faster under the tongue than other options. Due to its higher bioavailability, Zubsolv uses different dosing strengths — a Zubsolv 5.7 mg/1.4 mg tablet is considered equivalent to a Suboxone 8 mg/2 mg dose. Patients switching between products should work closely with their prescriber for correct dose conversion.
Does Medicaid cover Suboxone treatment?
Yes — Medicaid covers buprenorphine (including Suboxone, Sublocade, Subutex, Zubsolv, and Brixadi) for opioid use disorder in all 50 states, as required by the SUPPORT Act of 2018. Medicaid is the largest single payer for MAT in the US. Coverage details vary by state — some require prior authorization or limit certain formulations. Many OBOT clinics accept Medicaid directly; telehealth Suboxone providers also bill Medicaid in most states. Bring your Medicaid card to your intake appointment.
Can I get Suboxone through telehealth?
Yes. After the MAT Act of 2023 permanently eliminated the X-waiver requirement, any licensed prescriber can prescribe Suboxone via telehealth in most states. The DEA also extended COVID-era telehealth flexibilities through at least 2025, allowing virtual Suboxone induction without a prior in-person visit. Several specialty platforms — Bicycle Health, Ophelia, Workit Health, Boulder Care — offer Medicaid-accepting telehealth Suboxone treatment. Telehealth has dramatically expanded access in rural and underserved areas with no nearby OBOT physicians.

About Buprenorphine (Suboxone)

Buprenorphine is classified as a partial opioid agonist, meaning it activates opioid receptors in the brain but to a much lesser degree than full agonists such as heroin, fentanyl, or oxycodone. This partial activation suppresses withdrawal symptoms and reduces cravings without producing dangerous respiratory depression or intense euphoria. Buprenorphine also has an unusually high binding affinity for the mu-opioid receptor, effectively blocking other opioids from attaching — providing a protective effect against relapse-related overdose.

How Buprenorphine Works

One of the defining features of buprenorphine is its ceiling effect — after a certain dose threshold, increasing the amount does not produce additional opioid effects. This dramatically reduces the risk of fatal overdose compared to methadone or illicit opioids. The ceiling effect, combined with its long duration of action (24 to 72 hours), makes buprenorphine one of the safest and most effective tools in medication-assisted treatment (MAT). Approved by the FDA in 2002, buprenorphine was a breakthrough because it could be prescribed in outpatient settings rather than requiring daily clinic visits.

Buprenorphine Brand Comparison: Suboxone, Subutex, Sublocade, Zubsolv, Brixadi

Buprenorphine is available under several FDA-approved brand names, each with distinct formulations, dosing schedules, and clinical use cases. The comparison below highlights the key differences:

BrandActive ingredientFormFrequencySettingFDA yearBest for
SuboxoneBuprenorphine + naloxoneSublingual film / tabletDailyOBOT, telehealth, retail pharmacy2002Most prescribed; naloxone deters injection misuse
SubutexBuprenorphine (alone)Sublingual tabletDailyOBOT2002Pregnancy; documented naloxone sensitivity
SublocadeBuprenorphine extended-releaseSubcutaneous injection (ATRIGEL depot)MonthlyClinic-administered2017No daily dosing; eliminates diversion risk
ZubsolvBuprenorphine + naloxoneSublingual tablet (higher bioavailability)DailyOBOT2013Faster dissolution; mint flavor; lower mg/dose
BrixadiBuprenorphine extended-releaseSubcutaneous injectionWeekly or monthlyClinic2023Newer alternative to Sublocade; weekly option for induction

All five medications are Schedule III controlled substances and equivalent in clinical efficacy at appropriate doses. The choice depends on adherence patterns, lifestyle, insurance coverage, and clinical context (e.g., pregnancy, prior injection use, daily-dosing burden). Many patients begin on sublingual Suboxone for stabilization and transition to monthly Sublocade or weekly Brixadi after sustained recovery.

Buprenorphine Side Effects

Common buprenorphine side effects include:

  • Headache and dizziness
  • Nausea and vomiting, especially during induction
  • Constipation and insomnia
  • Excessive sweating
  • Mouth numbness or oral discomfort from sublingual formulations

More serious side effects may include respiratory depression (particularly when combined with benzodiazepines or alcohol), liver problems, and allergic reactions. For most patients, side effects are mild and resolve within one to two weeks. The benefits in preventing relapse and overdose death significantly outweigh the risks.

Buprenorphine Dosage and Induction

Treatment begins with an induction phase where the patient must be in mild to moderate opioid withdrawal. Common induction doses range from 2 mg to 8 mg on the first day, with increases over the following days. Most patients stabilize on 8 mg to 24 mg per day, with 16 mg being the most commonly prescribed dose. Research suggests doses of 16 mg or higher are associated with better retention and outcomes. Dosage should always be adjusted under medical supervision.

Buprenorphine/Naloxone Combination

Many buprenorphine formulations include naloxone as an abuse deterrent. When taken sublingually as directed, naloxone has very low bioavailability and produces no clinical effect. However, if someone attempts to inject the medication, the naloxone component becomes fully active and triggers severe withdrawal. This design discourages injection misuse while having no impact on patients who take the medication correctly. The combination is the standard first-line formulation for opioid addiction treatment.

Suboxone: Sublingual Buprenorphine

Suboxone is the most recognized brand name for buprenorphine-naloxone and is most commonly dispensed as a sublingual film (Suboxone strips) that dissolves under the tongue. Suboxone has transformed opioid treatment by enabling millions of patients to receive effective pharmacotherapy in outpatient settings without the daily clinic visits required by methadone programs.

Suboxone Side Effects

Commonly reported Suboxone side effects include headache, nausea, tongue or mouth irritation, constipation, insomnia, sweating, and decreased libido. The sublingual film can cause irritation or small sores inside the mouth — rotating placement between under the tongue and against the cheek helps minimize this. Patients should not eat, drink, or smoke while the film is dissolving.

Suboxone Strips: Film vs. Tablet

Suboxone strips (sublingual film) have largely replaced the original tablet form. The film dissolves more quickly (two to four minutes), provides more consistent absorption, and is harder to divert due to individual foil packaging. Generic buprenorphine-naloxone tablets are often less expensive and may be preferred for cost reasons. Both are therapeutically equivalent when taken as prescribed.

Suboxone Treatment Programs

Comprehensive Suboxone treatment typically includes three phases:

  • Induction: Initial dosing under medical supervision, requiring the patient to be in early withdrawal
  • Stabilization: Dose adjustment until cravings and withdrawal are minimal, usually one to two months
  • Maintenance: Stable dosing for an extended period — often a year or longer — combined with counseling and behavioral therapy

Evidence consistently shows that longer treatment durations are associated with better outcomes. Most addiction medicine experts recommend a minimum of one to two years of maintenance therapy.

Find a Suboxone Clinic Near You — OBOT & Telehealth Options

Finding a Suboxone clinic has become significantly easier since the federal government eliminated the X-waiver requirement in January 2023, meaning any provider with a standard DEA license can now prescribe Suboxone. Patients can search SAMHSA's treatment locator at findtreatment.gov or use our directory to locate nearby facilities that offer buprenorphine-based treatment.

Suboxone Doctors Near Me

Beyond SAMHSA's locator, many state health departments maintain directories of addiction treatment providers. Telehealth has dramatically expanded access — several platforms now offer virtual Suboxone consultations, which is especially valuable for patients in rural areas. When selecting a provider, look for those offering comprehensive treatment including counseling, not just medication prescriptions.

Suboxone Withdrawal and Tapering

Suboxone withdrawal can include muscle aches, anxiety, insomnia, nausea, sweating, and intense opioid cravings. A gradual, medically supervised taper is recommended — typically reducing the dose by 10 to 25 percent every one to four weeks. Slower tapers over several months produce fewer symptoms and lower relapse rates. There is no medically mandated time limit for Suboxone treatment, and many patients benefit from indefinite maintenance.

Suboxone vs Methadone

Suboxone can be prescribed in office settings and taken at home, carries lower overdose risk due to its ceiling effect, and offers greater scheduling flexibility. Methadone is a full agonist that may be more effective for severe, long-standing dependence but must be dispensed at licensed clinics with daily visits. Neither is inherently superior — the best choice keeps the patient in treatment. Some patients may also benefit from naltrexone, a non-opioid alternative.

Sublocade: Monthly Buprenorphine Injection

Sublocade delivers buprenorphine as a once-monthly subcutaneous injection in the abdominal area using the ATRIGEL delivery system, which forms a solid biodegradable depot that slowly releases medication. Patients must first stabilize on sublingual buprenorphine (8 mg+ daily) for at least seven days. Treatment typically begins with two 300 mg injections, followed by maintenance on 300 mg or 100 mg. Sublocade eliminates concerns about daily adherence, missed doses, and medication diversion.

Sublocade Side Effects

The most common Sublocade side effects are injection-site reactions (pain, itching, redness, or a noticeable lump), nausea, constipation, headache, and fatigue. The injection-site lump is normal and gradually diminishes as medication is absorbed. Patients should avoid rubbing or massaging the site. Elevated liver enzymes may also occur but are usually mild and transient.

Subutex: Buprenorphine Without Naloxone

Subutex was the original brand-name buprenorphine product. While the brand has been discontinued, generic buprenorphine-only tablets remain available. Buprenorphine monotherapy is typically reserved for pregnant patients (to avoid naloxone exposure to the fetus), patients with documented naloxone sensitivity, or sometimes during the induction phase before transitioning to the combination product.

Subutex vs Suboxone

The primary difference is the absence of naloxone in Subutex. Because Subutex lacks the abuse-deterrent naloxone component, it may carry slightly higher diversion risk, and many insurance formularies prioritize the combination as the default. Current clinical guidelines favor buprenorphine-only formulations primarily for pregnancy and naloxone sensitivity.

Zubsolv: Alternative Buprenorphine Brand

Zubsolv is a buprenorphine-naloxone sublingual tablet featuring a mint flavor and faster dissolution (under two minutes). Due to enhanced bioavailability, Zubsolv uses different dose strengths — a 5.7 mg/1.4 mg tablet equals a Suboxone 8 mg/2 mg dose. Zubsolv is available in multiple strengths for flexible dosing during both induction and maintenance.

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Medically Reviewed Updated July 2026

Reviewed by licensed addiction specialists. Information reflects current clinical guidance.

Sources:SAMHSA·NIDA·CDC

Need immediate help? Call SAMHSA: 1-800-662-4357 (24/7, free)