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Medically Reviewed Content
Updated: July 2026
Sources: SAMHSA, NIDA

Suboxone Clinic Near You: Buprenorphine Treatment for Opioid Addiction

Find a Suboxone clinic near you. Buprenorphine — sold under brand names Suboxone, Sublocade, Subutex, Zubsolv, and Brixadi — is the most-prescribed MAT for opioid use disorder. It is a partial mu-opioid agonist with a ceiling effect that dramatically reduces overdose risk vs. methadone. After the MAT Act of 2023 eliminated the X-waiver requirement, any licensed prescriber can prescribe buprenorphine in office-based settings (OBOT), via telehealth, or at retail pharmacies. Buprenorphine is a Schedule III controlled substance and is covered by Medicaid in all 50 states.

Found 7,145 treatment centers offering buprenorphine (suboxone) across the United States.

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Therapeutic Health Services

Therapeutic Health Services in Seattle, WA, provides targeted support for adults struggling with substance use disorders, particularly those also managing serious mental health conditions or emotional challenges in children. Their services include robust intensive outpatient and outpatient care options, featuring medication-assisted treatment like methadone, buprenorphine, or naltrexone. Employing evidence-based methods such as cognitive behavioral therapy, motivational interviewing, and relapse prevention strategies, the center assists adult men and women, including survivors of intimate partner or domestic violence. Therapeutic Health Services is dedicated to offering personalized, high-quality rehabilitation for adults and young adults of all genders in the Seattle community.

Therapeutic Health Services

Therapeutic Health Services in Seattle, WA, provides comprehensive outpatient care for substance use disorders, concentrating on medication-assisted treatment with methadone, buprenorphine, or naltrexone. Their approach integrates proven methods like cognitive behavioral therapy, motivational interviewing, and strategies for preventing relapse. The center is dedicated to personalized treatment plans, offering distinct programs for adult men and women, and for individuals affected by domestic or intimate partner violence. Catering to adults and young adults across all gender identities, this establishment delivers a holistic and customized path to addiction recovery and sustained wellness.

Therapeutic Health Services

Therapeutic Health Services, situated in Kent, WA, provides outpatient addiction treatment for adults and adolescents facing dual diagnoses of substance use and significant mental health challenges. The center features tailored programs for adult men, adult women, and survivors of domestic or intimate partner abuse. Employing therapeutic techniques such as cognitive behavioral therapy and motivational interviewing, the facility emphasizes individualized treatment plans. Therapeutic Health Services offers outpatient care with methadone, buprenorphine, or naltrexone, fostering a thorough and encouraging atmosphere for healing. This establishment is dedicated to delivering high-quality services for individuals addressing either substance use or mental health issues.

Therapeutic Health Services

Therapeutic Health Services located in Seattle, WA, delivers focused treatment for adults dealing with substance use issues alongside mental health disorders, and it also addresses significant emotional difficulties in children. The center features both intensive outpatient and standard outpatient programs designed to offer personalized support, utilizing techniques such as cognitive behavioral therapy, motivational interviewing, and strategies to prevent relapse. Special programs are available for adult men, women, and those who have endured domestic or intimate partner violence. Committed to serving adults and young adults of all genders, this center emphasizes high-quality care and personalized attention to foster sustainable recovery and overall health.

Therapeutic Health Services

Therapeutic Health Services in Bellevue, WA, is dedicated to providing specialized care for adults grappling with substance use disorders alongside co-occurring serious mental health conditions or emotional challenges. Their offerings include intensive outpatient and standard outpatient services, employing proven methodologies such as cognitive behavioral therapy, motivational interviewing, and relapse prevention strategies. The center also provides customized programs catering to adult men, women, and survivors of intimate partner violence. Open to adults and young adults across all gender identities, this facility ensures comprehensive support through personalized treatment plans rooted in evidence-based practices. Embrace a nurturing setting designed to foster sustained recovery and enhance overall mental wellness.

Thomas Memorial Hospital

Located in Charleston, WV, Thomas Memorial Hospital provides expert rehabilitation services designed for both adults and young adults facing challenges with substance abuse and concurrent mental health disorders. This center features a range of treatment options, including intensive outpatient programs, outpatient support, and therapies using methadone, buprenorphine, or naltrexone. Emphasizing approaches like 12-step programs, anger management, and short interventions, it aims to meet the diverse needs of individuals requiring thorough assistance. The facility is especially skilled in addressing the complexities of dual diagnoses and offers customized programs for both male and female clientele. At Thomas Memorial Hospital, you can anticipate a caring environment and treatments grounded in evidence-based practices.

Thrive Medical Group Inc

Thrive Medical Group Inc located in Englewood, CO specializes in outpatient detox services and treatment for substance use disorders in both adults and adolescents. The facility offers outpatient options including methadone, buprenorphine, or naltrexone therapy, and incorporates cognitive behavioral therapy, counseling for substance use disorders, and telehealth services. With an emphasis on personalized treatment plans, the center serves clients of all genders. Thrive Medical Group Inc is recognized for its holistic approach to addiction recovery, providing thorough care and assistance to individuals on their journey to healing.

Thrive Treatment
Santa Monica, CA

Nestled in Santa Monica, California, Thrive Treatment delivers a complete spectrum of care for individuals battling substance abuse and co-occurring mental health challenges, serving both youth and adults. They offer structured programs like intensive outpatient, day treatment, and partial hospitalization, employing proven therapeutic methods such as 12-step facilitation, brief intervention, and cognitive behavioral therapy. Thrive Treatment is equipped to support distinct groups, including adolescents, adult men, and adult women, providing individualized support. Committed to high standards and personalized recovery plans, this establishment aims to guide clients toward sustained sobriety and emotional wellness.

Thresholds
Chicago, IL

Located in Chicago, IL, Thresholds delivers a wide array of rehabilitation services aimed at adults and young adults. The center focuses on detoxification, substance abuse treatment, and addressing co-occurring substance use with significant mental health challenges in adults or severe emotional disturbances in children. Treatment modalities include intensive outpatient programs, general outpatient services, and outpatient detox options. Thresholds employs various techniques such as anger management, brief interventions, and cognitive behavioral therapy. The facility also offers specialized programs designed for adult men and women, as well as those who have faced trauma. With a commitment to personalized care, Thresholds ensures a nurturing and effective rehabilitation journey for all clients.

Thelma McMillen Recovery Center

The Thelma McMillen Recovery Center in Torrance, CA, provides extensive care for adults struggling with addiction and co-occurring serious mental health conditions, as well as for children facing significant emotional disorders. They employ a range of therapeutic techniques, including 12-step facilitation, cognitive behavioral therapy, and motivational interviewing, within structured intensive outpatient and outpatient services. The center is equipped to serve adolescents, adult men, and adult women, accommodating diverse age ranges and genders. Their commitment to evidence-based practices and distinct treatment plans guarantees a high standard of support for individuals pursuing recovery from substance abuse and mental health concerns.

Therapeutics LLC
Ann Arbor, MI

Therapeutics LLC, located in Ann Arbor, MI, is a leading provider of outpatient detoxification and comprehensive substance use disorder treatment for adults and young adults. The center is distinguished by its specialized expertise in supporting individuals who have endured trauma, including experiences of intimate partner violence, domestic violence, and sexual abuse. Therapeutics LLC prioritizes personalized care, utilizing evidence-based approaches such as anger management, cognitive behavioral therapy, and motivational incentives to address each client's unique journey. The facility offers outpatient medication-assisted treatment options, including methadone, buprenorphine, and naltrexone, serving both male and female patients. Their integrated treatment model and dedicated programs guarantee effective, high-quality support for those in recovery from addiction.

Therapeutics LLC
Pontiac, MI

Therapeutics LLC, located in Pontiac, MI, provides outpatient detox and treatment services for both adults and young adults dealing with substance use issues. This center has a particular emphasis on assisting individuals who have faced intimate partner violence, domestic abuse, sexual trauma, and related experiences. By implementing techniques such as anger management, cognitive behavioral therapy, and contingency management, Therapeutics LLC ensures personalized care for all clients, regardless of gender. Committed to delivering high-quality, customized treatment, the facility strives to guide clients through their recovery process using proven methods and a dedicated, supportive team.

Therapeutic Health Services

Therapeutic Health Services in Everett, WA, delivers an extensive selection of treatment options for substance use and co-occurring disorders, catering to both adults and children. The facility offers various levels of care, including intensive outpatient programs, day treatment, and partial hospitalization. By employing evidence-based methods such as cognitive behavioral therapy, motivational interviewing, and strategies for relapse prevention, this center effectively supports both men and women, including those affected by domestic or intimate partner violence. Therapeutic Health Services provides specialized interventions designed for both adults and young adults, ensuring that each client receives personalized care. With its commitment to high-quality, individualized treatment, the center is a leading option for individuals seeking reliable rehabilitation support.

Therapeutics LLC
Walled Lake, MI

Located in Walled Lake, MI, Therapeutics LLC provides outpatient detox and treatment services for substance use disorders aimed at both adults and young adults. The center has expertise in areas such as anger management, cognitive behavioral therapy, and motivational incentives. They focus on delivering personalized care for individuals who have faced issues like intimate partner violence, sexual abuse, or trauma. Therapeutics LLC emphasizes customized treatment approaches for all clients, regardless of gender, who are in search of thorough rehabilitation options. Renowned for its exceptional care and nurturing atmosphere, this facility is a leading option for individuals seeking effective and empathetic addiction support.

Therapeutics LLC

Therapeutics LLC, located in Monroe, MI, provides outpatient detox services and treatment for substance use disorders, along with tailored programs for those affected by trauma, including intimate partner violence, domestic violence, and sexual abuse. The center specializes in techniques such as anger management, cognitive behavioral therapy, and motivational incentives, serving both adult and young adult males and females who are on the path to recovery. Its facility offers outpatient treatment options like methadone/buprenorphine or naltrexone in a nurturing atmosphere. At Therapeutics LLC, the emphasis is on delivering high-quality, personalized care to support clients in their quest for sobriety and emotional healing.

Thunderbird Treatment Center

Nestled in Glendale, AZ, Thunderbird Treatment Center is dedicated to providing specialized outpatient care for individuals struggling with addiction. They focus on detoxification and comprehensive substance use treatment, offering services such as medication-assisted treatment with methadone, buprenorphine, or naltrexone, as well as remote therapy options for ongoing support and counseling. Tailored programs are available for adult men, adult women, and clients living with HIV or AIDS, catering to a diverse adult population including seniors and young adults. Thunderbird Treatment Center is committed to delivering exceptional care and personalized recovery plans for everyone who walks through their doors.

Thomas Jefferson University Center for

Situated in Philadelphia, PA, the Thomas Jefferson University Center for specializes in a wide range of outpatient programs for substance use recovery. This center offers tailored services for adult men and women, including individuals facing dual diagnoses of mental health and substance use disorders. Emphasizing methods like 12-step support, anger management, and brief interventions, the center is dedicated to providing personalized treatment options for both adults and young adults. With services that include outpatient methadone/buprenorphine or naltrexone therapies alongside standard outpatient care, this facility is committed to delivering high-quality support for all clients, regardless of gender.

Thresholds Inc
Georgetown, DE

Thresholds Inc, situated in Georgetown, DE, delivers focused outpatient services for individuals battling substance use challenges. Their approach encompasses a spectrum of evidence-based modalities, including 12-step integration, cognitive behavioral therapy, and the Matrix Model. They also provide specialized care for those managing dual diagnoses, such as co-occurring mental health and substance use issues, and individuals dealing with pain alongside addiction. Thresholds Inc warmly welcomes adults and young adults, irrespective of gender, fostering an inclusive and encouraging atmosphere. Their commitment lies in providing top-tier care and personalized recovery pathways to support individuals on their journey to sustained sobriety.

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Therapeutic Wellness Services Inc., located in Baltimore, MD, delivers extensive recovery support. Their offerings include programs for substance dependence, temporary accommodations, and care for dual diagnoses involving addiction and significant mental health conditions or emotional distress. The center features intensive outpatient, extended residential stays, and standard outpatient services. Their therapeutic methods incorporate anger de-escalation, cognitive restructuring, and community-based support with incentives. Specialized initiatives are designed for adult males, adult females, and survivors of domestic abuse. Catering to adults and young adults regardless of gender identity, this establishment prioritizes individualized treatment and assistance for those aiming to conquer addiction and mental health struggles.

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Woodstock, IL

Thresholds, situated in Woodstock, IL, delivers targeted substance abuse recovery services for adults experiencing concurrent mental health challenges. This establishment features robust outpatient programs incorporating cognitive behavioral techniques, motivational dialogue, and addiction counseling. Designed for individuals with dual diagnoses, Thresholds provides outpatient management with methadone, buprenorphine, or naltrexone. Prioritizing excellent care, the center serves adult men and women seeking thorough assistance for addiction and accompanying mental health concerns. For specialized care in a nurturing setting, Thresholds is a resource.

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Chicago, IL

Thresholds, situated in Chicago, IL, delivers targeted rehabilitation services for adults grappling with substance use issues and concurrent mental health challenges. The center features a range of options including intensive outpatient programs, standard outpatient services, and treatments involving methadone, buprenorphine, or naltrexone. With an emphasis on evidence-based methods such as cognitive behavioral therapy and motivational interviewing, the center prioritizes personalized care to foster recovery. Specifically tailored to assist clients facing both mental health and substance use disorders, Thresholds offers extensive support for adult men and women aiming to conquer addiction and enhance their emotional health.

Frequently Asked Questions

What is buprenorphine and how does it treat opioid addiction?
Buprenorphine is a partial opioid agonist medication approved by the FDA for treating opioid use disorder. It binds to the same receptors as heroin and fentanyl but produces a much weaker effect, reducing cravings and withdrawal symptoms without causing intense euphoria. Buprenorphine has a ceiling effect, meaning its opioid effects plateau at moderate doses, making it safer than methadone in terms of overdose risk.
What is the difference between Suboxone and Subutex?
Suboxone contains two active ingredients — buprenorphine and naloxone — while Subutex contains only buprenorphine without naloxone. The naloxone in Suboxone is included as an abuse deterrent; it remains inactive when taken sublingually as prescribed but triggers withdrawal if the medication is injected. Subutex is generally reserved for patients who cannot tolerate naloxone, such as pregnant women.
What is a Sublocade injection and how does it work?
Sublocade is a once-monthly injectable form of buprenorphine administered as a subcutaneous injection in the abdominal area. After injection, the medication forms a solid deposit under the skin that slowly releases buprenorphine over the course of a month. This eliminates daily dosing and removes the possibility of missed doses or medication diversion.
What are the common side effects of Suboxone?
Common Suboxone side effects include headache, nausea, constipation, insomnia, sweating, and mouth numbness or pain from sublingual administration. Some patients also experience dizziness, drowsiness, and blurred vision, particularly when starting treatment. Most side effects diminish within the first few weeks as the body adjusts. Patients should report difficulty breathing or signs of allergic reaction immediately.
What happens during Suboxone withdrawal?
Suboxone withdrawal occurs when a patient stops taking the medication abruptly after prolonged use, with symptoms including muscle aches, anxiety, insomnia, nausea, and irritability. A medically supervised taper is strongly recommended, typically reducing the dose by small increments over weeks or months. The risk of opioid relapse is significantly higher during unsupervised discontinuation.
How does Suboxone compare to methadone?
Suboxone and methadone are both effective for opioid use disorder but differ in key ways. Methadone is a full opioid agonist dispensed daily at licensed clinics, while Suboxone is a partial agonist that can be prescribed by qualified physicians and taken at home. Suboxone carries a lower overdose risk due to its ceiling effect and offers greater convenience, though methadone may be more appropriate for patients with severe, long-standing dependence.
How can I find a Suboxone clinic or doctor near me?
The most reliable way to find a Suboxone provider is through SAMHSA's online treatment locator at findtreatment.gov, which allows you to search by location and filter for buprenorphine providers. Many primary care offices, addiction treatment centers, and telehealth platforms now offer Suboxone prescriptions following the elimination of the federal X-waiver requirement in early 2023.
What is Zubsolv and how is it different from Suboxone?
Zubsolv is a brand-name buprenorphine and naloxone sublingual tablet that features a mint flavor and dissolves faster under the tongue than other options. Due to its higher bioavailability, Zubsolv uses different dosing strengths — a Zubsolv 5.7 mg/1.4 mg tablet is considered equivalent to a Suboxone 8 mg/2 mg dose. Patients switching between products should work closely with their prescriber for correct dose conversion.
Does Medicaid cover Suboxone treatment?
Yes — Medicaid covers buprenorphine (including Suboxone, Sublocade, Subutex, Zubsolv, and Brixadi) for opioid use disorder in all 50 states, as required by the SUPPORT Act of 2018. Medicaid is the largest single payer for MAT in the US. Coverage details vary by state — some require prior authorization or limit certain formulations. Many OBOT clinics accept Medicaid directly; telehealth Suboxone providers also bill Medicaid in most states. Bring your Medicaid card to your intake appointment.
Can I get Suboxone through telehealth?
Yes. After the MAT Act of 2023 permanently eliminated the X-waiver requirement, any licensed prescriber can prescribe Suboxone via telehealth in most states. The DEA also extended COVID-era telehealth flexibilities through at least 2025, allowing virtual Suboxone induction without a prior in-person visit. Several specialty platforms — Bicycle Health, Ophelia, Workit Health, Boulder Care — offer Medicaid-accepting telehealth Suboxone treatment. Telehealth has dramatically expanded access in rural and underserved areas with no nearby OBOT physicians.

About Buprenorphine (Suboxone)

Buprenorphine is classified as a partial opioid agonist, meaning it activates opioid receptors in the brain but to a much lesser degree than full agonists such as heroin, fentanyl, or oxycodone. This partial activation suppresses withdrawal symptoms and reduces cravings without producing dangerous respiratory depression or intense euphoria. Buprenorphine also has an unusually high binding affinity for the mu-opioid receptor, effectively blocking other opioids from attaching — providing a protective effect against relapse-related overdose.

How Buprenorphine Works

One of the defining features of buprenorphine is its ceiling effect — after a certain dose threshold, increasing the amount does not produce additional opioid effects. This dramatically reduces the risk of fatal overdose compared to methadone or illicit opioids. The ceiling effect, combined with its long duration of action (24 to 72 hours), makes buprenorphine one of the safest and most effective tools in medication-assisted treatment (MAT). Approved by the FDA in 2002, buprenorphine was a breakthrough because it could be prescribed in outpatient settings rather than requiring daily clinic visits.

Buprenorphine Brand Comparison: Suboxone, Subutex, Sublocade, Zubsolv, Brixadi

Buprenorphine is available under several FDA-approved brand names, each with distinct formulations, dosing schedules, and clinical use cases. The comparison below highlights the key differences:

BrandActive ingredientFormFrequencySettingFDA yearBest for
SuboxoneBuprenorphine + naloxoneSublingual film / tabletDailyOBOT, telehealth, retail pharmacy2002Most prescribed; naloxone deters injection misuse
SubutexBuprenorphine (alone)Sublingual tabletDailyOBOT2002Pregnancy; documented naloxone sensitivity
SublocadeBuprenorphine extended-releaseSubcutaneous injection (ATRIGEL depot)MonthlyClinic-administered2017No daily dosing; eliminates diversion risk
ZubsolvBuprenorphine + naloxoneSublingual tablet (higher bioavailability)DailyOBOT2013Faster dissolution; mint flavor; lower mg/dose
BrixadiBuprenorphine extended-releaseSubcutaneous injectionWeekly or monthlyClinic2023Newer alternative to Sublocade; weekly option for induction

All five medications are Schedule III controlled substances and equivalent in clinical efficacy at appropriate doses. The choice depends on adherence patterns, lifestyle, insurance coverage, and clinical context (e.g., pregnancy, prior injection use, daily-dosing burden). Many patients begin on sublingual Suboxone for stabilization and transition to monthly Sublocade or weekly Brixadi after sustained recovery.

Buprenorphine Side Effects

Common buprenorphine side effects include:

  • Headache and dizziness
  • Nausea and vomiting, especially during induction
  • Constipation and insomnia
  • Excessive sweating
  • Mouth numbness or oral discomfort from sublingual formulations

More serious side effects may include respiratory depression (particularly when combined with benzodiazepines or alcohol), liver problems, and allergic reactions. For most patients, side effects are mild and resolve within one to two weeks. The benefits in preventing relapse and overdose death significantly outweigh the risks.

Buprenorphine Dosage and Induction

Treatment begins with an induction phase where the patient must be in mild to moderate opioid withdrawal. Common induction doses range from 2 mg to 8 mg on the first day, with increases over the following days. Most patients stabilize on 8 mg to 24 mg per day, with 16 mg being the most commonly prescribed dose. Research suggests doses of 16 mg or higher are associated with better retention and outcomes. Dosage should always be adjusted under medical supervision.

Buprenorphine/Naloxone Combination

Many buprenorphine formulations include naloxone as an abuse deterrent. When taken sublingually as directed, naloxone has very low bioavailability and produces no clinical effect. However, if someone attempts to inject the medication, the naloxone component becomes fully active and triggers severe withdrawal. This design discourages injection misuse while having no impact on patients who take the medication correctly. The combination is the standard first-line formulation for opioid addiction treatment.

Suboxone: Sublingual Buprenorphine

Suboxone is the most recognized brand name for buprenorphine-naloxone and is most commonly dispensed as a sublingual film (Suboxone strips) that dissolves under the tongue. Suboxone has transformed opioid treatment by enabling millions of patients to receive effective pharmacotherapy in outpatient settings without the daily clinic visits required by methadone programs.

Suboxone Side Effects

Commonly reported Suboxone side effects include headache, nausea, tongue or mouth irritation, constipation, insomnia, sweating, and decreased libido. The sublingual film can cause irritation or small sores inside the mouth — rotating placement between under the tongue and against the cheek helps minimize this. Patients should not eat, drink, or smoke while the film is dissolving.

Suboxone Strips: Film vs. Tablet

Suboxone strips (sublingual film) have largely replaced the original tablet form. The film dissolves more quickly (two to four minutes), provides more consistent absorption, and is harder to divert due to individual foil packaging. Generic buprenorphine-naloxone tablets are often less expensive and may be preferred for cost reasons. Both are therapeutically equivalent when taken as prescribed.

Suboxone Treatment Programs

Comprehensive Suboxone treatment typically includes three phases:

  • Induction: Initial dosing under medical supervision, requiring the patient to be in early withdrawal
  • Stabilization: Dose adjustment until cravings and withdrawal are minimal, usually one to two months
  • Maintenance: Stable dosing for an extended period — often a year or longer — combined with counseling and behavioral therapy

Evidence consistently shows that longer treatment durations are associated with better outcomes. Most addiction medicine experts recommend a minimum of one to two years of maintenance therapy.

Find a Suboxone Clinic Near You — OBOT & Telehealth Options

Finding a Suboxone clinic has become significantly easier since the federal government eliminated the X-waiver requirement in January 2023, meaning any provider with a standard DEA license can now prescribe Suboxone. Patients can search SAMHSA's treatment locator at findtreatment.gov or use our directory to locate nearby facilities that offer buprenorphine-based treatment.

Suboxone Doctors Near Me

Beyond SAMHSA's locator, many state health departments maintain directories of addiction treatment providers. Telehealth has dramatically expanded access — several platforms now offer virtual Suboxone consultations, which is especially valuable for patients in rural areas. When selecting a provider, look for those offering comprehensive treatment including counseling, not just medication prescriptions.

Suboxone Withdrawal and Tapering

Suboxone withdrawal can include muscle aches, anxiety, insomnia, nausea, sweating, and intense opioid cravings. A gradual, medically supervised taper is recommended — typically reducing the dose by 10 to 25 percent every one to four weeks. Slower tapers over several months produce fewer symptoms and lower relapse rates. There is no medically mandated time limit for Suboxone treatment, and many patients benefit from indefinite maintenance.

Suboxone vs Methadone

Suboxone can be prescribed in office settings and taken at home, carries lower overdose risk due to its ceiling effect, and offers greater scheduling flexibility. Methadone is a full agonist that may be more effective for severe, long-standing dependence but must be dispensed at licensed clinics with daily visits. Neither is inherently superior — the best choice keeps the patient in treatment. Some patients may also benefit from naltrexone, a non-opioid alternative.

Sublocade: Monthly Buprenorphine Injection

Sublocade delivers buprenorphine as a once-monthly subcutaneous injection in the abdominal area using the ATRIGEL delivery system, which forms a solid biodegradable depot that slowly releases medication. Patients must first stabilize on sublingual buprenorphine (8 mg+ daily) for at least seven days. Treatment typically begins with two 300 mg injections, followed by maintenance on 300 mg or 100 mg. Sublocade eliminates concerns about daily adherence, missed doses, and medication diversion.

Sublocade Side Effects

The most common Sublocade side effects are injection-site reactions (pain, itching, redness, or a noticeable lump), nausea, constipation, headache, and fatigue. The injection-site lump is normal and gradually diminishes as medication is absorbed. Patients should avoid rubbing or massaging the site. Elevated liver enzymes may also occur but are usually mild and transient.

Subutex: Buprenorphine Without Naloxone

Subutex was the original brand-name buprenorphine product. While the brand has been discontinued, generic buprenorphine-only tablets remain available. Buprenorphine monotherapy is typically reserved for pregnant patients (to avoid naloxone exposure to the fetus), patients with documented naloxone sensitivity, or sometimes during the induction phase before transitioning to the combination product.

Subutex vs Suboxone

The primary difference is the absence of naloxone in Subutex. Because Subutex lacks the abuse-deterrent naloxone component, it may carry slightly higher diversion risk, and many insurance formularies prioritize the combination as the default. Current clinical guidelines favor buprenorphine-only formulations primarily for pregnancy and naloxone sensitivity.

Zubsolv: Alternative Buprenorphine Brand

Zubsolv is a buprenorphine-naloxone sublingual tablet featuring a mint flavor and faster dissolution (under two minutes). Due to enhanced bioavailability, Zubsolv uses different dose strengths — a 5.7 mg/1.4 mg tablet equals a Suboxone 8 mg/2 mg dose. Zubsolv is available in multiple strengths for flexible dosing during both induction and maintenance.

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Medically Reviewed Updated July 2026

Reviewed by licensed addiction specialists. Information reflects current clinical guidance.

Sources:SAMHSA·NIDA·CDC

Need immediate help? Call SAMHSA: 1-800-662-4357 (24/7, free)