NWVCIL Logo
Medically Reviewed Content
Updated: July 2026
Sources: SAMHSA, NIDA

Suboxone Clinic Near You: Buprenorphine Treatment for Opioid Addiction

Find a Suboxone clinic near you. Buprenorphine — sold under brand names Suboxone, Sublocade, Subutex, Zubsolv, and Brixadi — is the most-prescribed MAT for opioid use disorder. It is a partial mu-opioid agonist with a ceiling effect that dramatically reduces overdose risk vs. methadone. After the MAT Act of 2023 eliminated the X-waiver requirement, any licensed prescriber can prescribe buprenorphine in office-based settings (OBOT), via telehealth, or at retail pharmacies. Buprenorphine is a Schedule III controlled substance and is covered by Medicaid in all 50 states.

Found 7,145 treatment centers offering buprenorphine (suboxone) across the United States.

Need Help Finding the Right Treatment Center?

Speak with a compassionate specialist now - 100% free & confidential

Call +1 (833) 244-3031
Available 24/7
All 50 States
Filters:

Showing 21 of 7145 results

Townsend Recovery Center

Townsend Recovery Center, located in Covington, LA, provides a wide array of addiction recovery services designed for both adults and young adults. The center facilitates detox programs, treatment for substance use disorders, and offers targeted assistance for individuals dealing with simultaneous substance use and serious mental health challenges. Various treatment options are available, including intensive outpatient care, long-term residential stays, and outpatient services, ensuring that different needs are met. Emphasizing a comprehensive recovery process, Townsend Recovery Center incorporates 12-step support, anger management techniques, and short-term interventions. With specialized programs for men, women, and individuals who have faced trauma, the center showcases its dedication to personalized treatment. Townsend Recovery Center is committed to delivering high-quality care, focusing on helping clients achieve lasting sobriety.

Tranquil Shores
Saint Petersburg, FL

Tranquil Shores, situated in Saint Petersburg, FL, specializes in a wide range of rehabilitation services aimed at adults and young adults confronting substance abuse and simultaneous mental health challenges. The center offers intensive outpatient therapy, day treatment programs, and partial hospitalization options, employing methods like 12-step support, anger management techniques, and brief therapeutic interventions. To cater to specific needs, Tranquil Shores includes targeted programs for active military members and both male and female adults, ensuring personalized treatment for everyone. Dedicated to delivering high-quality care, this facility emphasizes a holistic approach to recovery, guiding clients toward sustainable wellness.

Tranquility Woods LLC

Tranquility Woods LLC, located in Pasadena, MD, presents a variety of targeted treatment options for both adults and young adults facing challenges with substance use disorders as well as related mental health issues. This center delivers a full range of services, including inpatient detoxification and treatment services in a hospital setting, emphasizing approaches like 12-step programs, anger management, and brief interventions. Specific programs are designed for active duty service members, as well as specialized support for adult men and women. Tranquility Woods LLC is devoted to offering high-quality care in a nurturing environment, ensuring that individuals pursuing recovery receive personalized attention and support tailored to their unique circumstances. The facility fosters a safe and empathetic atmosphere conducive to healing.

Transformations at Mending Fences LLC

Transformations at Mending Fences LLC in Morriston, FL provides thorough addiction recovery services and dedicated support for those facing concurrent serious mental health conditions or emotional distress. This center offers extended residential stays, outpatient care, and day treatment programs, employing methods like 12-step encouragement, impulse control training, and rapid intervention strategies. Featuring distinct programs for active military members, adult males, and adult females, the facility serves adults and young adults across all gender identities. Transformations at Mending Fences LLC is devoted to offering superior, personalized attention to aid individuals in their path toward healing.

Transformations by the Gulf
Saint Petersburg, FL

Nestled in Saint Petersburg, FL, Transformations by the Gulf is a premier addiction recovery facility serving adults and young adults. They provide a spectrum of care, including intensive outpatient, outpatient, and partial hospitalization programs. The center's therapeutic approach incorporates 12-step facilitation, anger management, and brief intervention strategies, addressing the needs of adult men and women, including those with trauma histories. Transformations by the Gulf delivers personalized recovery plans, making it a distinguished choice for effective and caring substance use disorder treatment.

Transformations Treatment Center Inc

Transformations Treatment Center Inc, located in Delray Beach, FL, delivers a range of rehabilitation services including intensive outpatient, outpatient, and day treatment specifically designed for individuals dealing with substance abuse and concurrent mental health issues. The center features dedicated programs aimed at active duty military personnel as well as separate tracks for adult men and women. Clients benefit from various therapeutic methods such as 12-step support, anger management, and brief intervention strategies. Suitable for adults and young adults of all genders, this facility prioritizes personalized care and employs evidence-based techniques to foster a comprehensive recovery experience. Transformations Treatment Center Inc is recognized for its emphasis on high-quality care and extensive support, making it an excellent option for those in search of effective rehabilitation solutions within the Delray Beach community.

Transformations Care Inc

Transformations Care Inc, located in Gardena, CA, delivers thorough addiction recovery programs, encompassing both detox and ongoing substance abuse treatment. Prioritizing hospital-level inpatient care and round-the-clock availability, this establishment supports adults and young adults across all gender identities. The center distinguishes itself with tailored interventions like 12-step support, emotional regulation training, and custom-fit treatment strategies, ensuring each person receives uniquely suited assistance. Transformations Care Inc is recognized for its dedication to superior care and customized recovery journeys, establishing it as a premier destination for effective and empathetic addiction treatment in the Gardena community.

Transcendence Treatment Center LLC

Transcendence Treatment Center LLC, located in North Charleston, SC, delivers extensive addiction recovery services for adults and young adults. They feature intensive outpatient, standard outpatient, and day treatment programs. The center utilizes personalized care strategies, including anger management, brief intervention, and cognitive behavioral therapy. Designed for individual needs, their programs welcome both men and women. Transcendence Treatment Center LLC is committed to providing excellent care and guiding individuals toward lasting sobriety.

Towns Health Services/Lodi

Towns Health Services/Lodi in Lodi, CA provides expert care for individuals facing challenges with substance use. Their services are comprehensive, addressing co-occurring substance use disorders and serious mental health conditions in adults, as well as serious emotional disturbances in children. The center offers various levels of care, including intensive outpatient, outpatient, and partial hospitalization programs. Utilizing proven methods like 12-step facilitation, anger management, and brief intervention, they support adult men and women, alongside active duty military members. Towns Health Services/Lodi is dedicated to delivering effective treatment to adults and young adults, tailoring interventions to each person's unique needs through evidence-based strategies.

TPC Substance Use Outpatient Services

Situated in Amarillo, TX, TPC Substance Use Outpatient Services delivers focused outpatient care for individuals dealing with substance use issues and overlapping mental health conditions in both adults and children. The center employs strategies such as brief intervention, cognitive behavioral therapy, and community reinforcement in conjunction with vouchers to offer customized assistance to its clients, regardless of gender. Prioritizing individualized care, TPC Substance Use Outpatient Services is designed for adults and young adults who are in search of thorough support in an outpatient setting. If you or someone you know is in need of effective substance use treatment that emphasizes a tailored approach, this center is committed to facilitating a successful recovery journey.

Toxicology Associates/North Georgia

Toxicology Associates/North Georgia in Carrollton, GA, is a premier provider of outpatient care for addiction and withdrawal management. They offer a full spectrum of services, including specialized outpatient detox and medication-assisted treatment with methadone, buprenorphine, or naltrexone. Their program is designed for adults and young adults, with a particular emphasis on supporting pregnant and postpartum women. Using evidence-based methods such as brief intervention, CBT, and motivational incentives, they develop personalized recovery plans. Both male and female patients receive exceptional support at this center, establishing it as a leading choice for addiction recovery in North Georgia.

Toxicology Associates/North Georgia

Toxicology Associates/North Georgia, situated in Marietta, GA, is a prominent rehabilitation center that specializes in outpatient detoxification and treatment for substance use disorders. This facility is dedicated to providing individualized care for pregnant or postpartum women, as well as adults and young adults. Emphasizing high-quality treatment, the center employs a range of techniques such as brief intervention, cognitive behavioral therapy, and motivational incentives through contingency management. Clients can anticipate personalized care within a nurturing atmosphere. Additionally, the program includes outpatient options for methadone, buprenorphine, or naltrexone treatment. Both men and women can benefit from the compassionate and effective addiction recovery services available at Toxicology Associates/North Georgia.

Transformation Healthcare Inc

Situated in Baltimore, MD, Transformation Healthcare Inc delivers targeted rehabilitation programs for both adults and young adults struggling with substance abuse issues and simultaneous mental health disorders. The center offers a range of treatment options such as intensive outpatient programs, outpatient services, and day treatment, all customized to meet the unique requirements of clients. Emphasizing 12-step support, anger management, and brief intervention techniques, the facility serves active duty military members as well as adult men and women. With a commitment to providing exceptional care for all clients, Transformation Healthcare Inc is distinguished by its all-encompassing programs aimed at fostering recovery and overall wellness.

Transformation House

Transformation House, situated in Anoka, MN, delivers thorough addiction recovery services for adult males within a secure and nurturing setting. This establishment features extended residential stays, outpatient services, and round-the-clock residential care, employing methods like 12-step integration and emotional regulation techniques. Targeted interventions are available for individuals who have faced intimate partner violence, domestic abuse, and sexual trauma. Emphasizing the treatment of combined substance use and mental health challenges, Transformation House is committed to guiding adults, elder individuals, and younger adults toward sustained healing. The facility's high standards of care and tailored offerings position it as a crucial support system for those in pursuit of profound rehabilitation.

Transformation House I

Transformation House I, located in Anoka, MN, provides extended residential care for adult males battling substance dependence and concurrent severe mental health conditions. This establishment cultivates a secure and nurturing atmosphere for individuals moving from addiction toward lasting recovery. Recognizing the distinct challenges faced by those affected by intimate partner violence, domestic abuse, and sexual trauma, the center delivers personalized support addressing specific concerns. Transformation House I employs proven therapeutic methods, including 12-step program integration and emotional regulation strategies, to foster recovery and personal development. Emphasizing customized recovery journeys and a pledge to high-caliber service, the facility is devoted to assisting clients in attaining sustained sobriety and psychological equilibrium.

Transformation House II

Transformation House II, situated in Minneapolis, MN, is dedicated to offering an extensive array of rehabilitation services designed specifically for adult women facing challenges related to substance use and concurrent mental health disorders. The center features various treatment options including intensive outpatient, long-term residential care, and general outpatient programs, employing methods like 12-step facilitation, anger management, and brief intervention strategies. It also provides specialized programs aimed at supporting adult women who have experienced intimate partner violence, domestic violence, and sexual abuse. With its commitment to high-quality care, Transformation House II is a welcoming space for adults, seniors, and young adults looking for a supportive, gender-sensitive environment to begin their path to recovery.

Transformation House III

Situated in Champlin, MN, Transformation House III specializes in providing treatment for substance use and transitional accommodations specifically for adult men. The center offers a range of services, including intensive outpatient care, outpatient day programs, and partial hospitalization aimed at individuals facing challenges related to co-occurring substance use and significant mental health disorders. Emphasizing strategies such as 12-step facilitation, anger management, and brief interventions, this facility supports clients who have experienced intimate partner violence, domestic violence, or sexual abuse. Catering to adults, including seniors and young adults, Transformation House III is committed to delivering effective care and guidance for those on their journey to recovery within a safe and organized setting.

Transformation Wellness Center

Situated in Klamath Falls, OR, the Transformation Wellness Center delivers extensive treatment programs for adults and young adults facing substance use challenges. This center specializes in intensive outpatient care, standard outpatient services, and offers methadone/buprenorphine or naltrexone therapy. Employing techniques such as anger management, the Matrix Model, and motivational interviewing, the center customizes its services to meet the unique needs of each client. With a commitment to personalized attention, the center serves both men and women who are seeking assistance on their path to recovery. For those in search of a facility that prioritizes tailored treatment and high-quality support, the Transformation Wellness Center is ready to assist.

Placeholder image

Toxicology Associates/North Georgia in Lawrenceville, GA, provides comprehensive outpatient services for individuals of all ages struggling with substance use disorders. They offer specialized treatment pathways for adults and young adults, with particular attention to the needs of pregnant and postpartum women. Employing proven therapeutic modalities such as cognitive behavioral therapy and contingency management, this center is dedicated to delivering exceptional care for those pursuing recovery. Their treatment offerings encompass outpatient medication-assisted treatment, including methadone, buprenorphine, and naltrexone, alongside brief intervention strategies. Catering to both male and female clients, Toxicology Associates/North Georgia offers a supportive and effective environment for individuals embarking on the path to lasting sobriety.

Placeholder image
San Diego, CA

Tradition One, situated in San Diego, CA, delivers long-term residential treatment for adult males dealing with substance use issues. This center features transitional housing within a halfway house framework, emphasizing anger management, cognitive behavioral therapy, and motivational interviewing techniques. Tradition One is particularly adept at helping clients who have faced intimate partner violence, domestic violence, and sexual abuse, catering to men of all ages, including seniors and young adults. The facility focuses on tailored care and evidence-based methods, ensuring clients receive the support they need on their recovery path. For those looking for a thorough and nurturing atmosphere to tackle substance use disorders, Tradition One in San Diego is recognized for its specialized programs and high-quality care.

Placeholder image

Transformation Healthcare Inc, located in Columbia, MD, specializes in the treatment of substance abuse and co-occurring mental health disorders for adults facing significant psychological challenges, as well as for children experiencing emotional issues. The facility offers a range of treatment modalities, including intensive outpatient programs, outpatient services, and day treatment options. By employing 12-step facilitation, anger management techniques, and concise intervention strategies, the center customizes its programs to fit the specific requirements of each client. Focusing on a personalized care model, Transformation Healthcare Inc caters to adults and young adults of all genders. Committed to providing exceptional care within a nurturing atmosphere, the center aims to support individuals as they navigate their recovery journey.

Frequently Asked Questions

What is buprenorphine and how does it treat opioid addiction?
Buprenorphine is a partial opioid agonist medication approved by the FDA for treating opioid use disorder. It binds to the same receptors as heroin and fentanyl but produces a much weaker effect, reducing cravings and withdrawal symptoms without causing intense euphoria. Buprenorphine has a ceiling effect, meaning its opioid effects plateau at moderate doses, making it safer than methadone in terms of overdose risk.
What is the difference between Suboxone and Subutex?
Suboxone contains two active ingredients — buprenorphine and naloxone — while Subutex contains only buprenorphine without naloxone. The naloxone in Suboxone is included as an abuse deterrent; it remains inactive when taken sublingually as prescribed but triggers withdrawal if the medication is injected. Subutex is generally reserved for patients who cannot tolerate naloxone, such as pregnant women.
What is a Sublocade injection and how does it work?
Sublocade is a once-monthly injectable form of buprenorphine administered as a subcutaneous injection in the abdominal area. After injection, the medication forms a solid deposit under the skin that slowly releases buprenorphine over the course of a month. This eliminates daily dosing and removes the possibility of missed doses or medication diversion.
What are the common side effects of Suboxone?
Common Suboxone side effects include headache, nausea, constipation, insomnia, sweating, and mouth numbness or pain from sublingual administration. Some patients also experience dizziness, drowsiness, and blurred vision, particularly when starting treatment. Most side effects diminish within the first few weeks as the body adjusts. Patients should report difficulty breathing or signs of allergic reaction immediately.
What happens during Suboxone withdrawal?
Suboxone withdrawal occurs when a patient stops taking the medication abruptly after prolonged use, with symptoms including muscle aches, anxiety, insomnia, nausea, and irritability. A medically supervised taper is strongly recommended, typically reducing the dose by small increments over weeks or months. The risk of opioid relapse is significantly higher during unsupervised discontinuation.
How does Suboxone compare to methadone?
Suboxone and methadone are both effective for opioid use disorder but differ in key ways. Methadone is a full opioid agonist dispensed daily at licensed clinics, while Suboxone is a partial agonist that can be prescribed by qualified physicians and taken at home. Suboxone carries a lower overdose risk due to its ceiling effect and offers greater convenience, though methadone may be more appropriate for patients with severe, long-standing dependence.
How can I find a Suboxone clinic or doctor near me?
The most reliable way to find a Suboxone provider is through SAMHSA's online treatment locator at findtreatment.gov, which allows you to search by location and filter for buprenorphine providers. Many primary care offices, addiction treatment centers, and telehealth platforms now offer Suboxone prescriptions following the elimination of the federal X-waiver requirement in early 2023.
What is Zubsolv and how is it different from Suboxone?
Zubsolv is a brand-name buprenorphine and naloxone sublingual tablet that features a mint flavor and dissolves faster under the tongue than other options. Due to its higher bioavailability, Zubsolv uses different dosing strengths — a Zubsolv 5.7 mg/1.4 mg tablet is considered equivalent to a Suboxone 8 mg/2 mg dose. Patients switching between products should work closely with their prescriber for correct dose conversion.
Does Medicaid cover Suboxone treatment?
Yes — Medicaid covers buprenorphine (including Suboxone, Sublocade, Subutex, Zubsolv, and Brixadi) for opioid use disorder in all 50 states, as required by the SUPPORT Act of 2018. Medicaid is the largest single payer for MAT in the US. Coverage details vary by state — some require prior authorization or limit certain formulations. Many OBOT clinics accept Medicaid directly; telehealth Suboxone providers also bill Medicaid in most states. Bring your Medicaid card to your intake appointment.
Can I get Suboxone through telehealth?
Yes. After the MAT Act of 2023 permanently eliminated the X-waiver requirement, any licensed prescriber can prescribe Suboxone via telehealth in most states. The DEA also extended COVID-era telehealth flexibilities through at least 2025, allowing virtual Suboxone induction without a prior in-person visit. Several specialty platforms — Bicycle Health, Ophelia, Workit Health, Boulder Care — offer Medicaid-accepting telehealth Suboxone treatment. Telehealth has dramatically expanded access in rural and underserved areas with no nearby OBOT physicians.

About Buprenorphine (Suboxone)

Buprenorphine is classified as a partial opioid agonist, meaning it activates opioid receptors in the brain but to a much lesser degree than full agonists such as heroin, fentanyl, or oxycodone. This partial activation suppresses withdrawal symptoms and reduces cravings without producing dangerous respiratory depression or intense euphoria. Buprenorphine also has an unusually high binding affinity for the mu-opioid receptor, effectively blocking other opioids from attaching — providing a protective effect against relapse-related overdose.

How Buprenorphine Works

One of the defining features of buprenorphine is its ceiling effect — after a certain dose threshold, increasing the amount does not produce additional opioid effects. This dramatically reduces the risk of fatal overdose compared to methadone or illicit opioids. The ceiling effect, combined with its long duration of action (24 to 72 hours), makes buprenorphine one of the safest and most effective tools in medication-assisted treatment (MAT). Approved by the FDA in 2002, buprenorphine was a breakthrough because it could be prescribed in outpatient settings rather than requiring daily clinic visits.

Buprenorphine Brand Comparison: Suboxone, Subutex, Sublocade, Zubsolv, Brixadi

Buprenorphine is available under several FDA-approved brand names, each with distinct formulations, dosing schedules, and clinical use cases. The comparison below highlights the key differences:

BrandActive ingredientFormFrequencySettingFDA yearBest for
SuboxoneBuprenorphine + naloxoneSublingual film / tabletDailyOBOT, telehealth, retail pharmacy2002Most prescribed; naloxone deters injection misuse
SubutexBuprenorphine (alone)Sublingual tabletDailyOBOT2002Pregnancy; documented naloxone sensitivity
SublocadeBuprenorphine extended-releaseSubcutaneous injection (ATRIGEL depot)MonthlyClinic-administered2017No daily dosing; eliminates diversion risk
ZubsolvBuprenorphine + naloxoneSublingual tablet (higher bioavailability)DailyOBOT2013Faster dissolution; mint flavor; lower mg/dose
BrixadiBuprenorphine extended-releaseSubcutaneous injectionWeekly or monthlyClinic2023Newer alternative to Sublocade; weekly option for induction

All five medications are Schedule III controlled substances and equivalent in clinical efficacy at appropriate doses. The choice depends on adherence patterns, lifestyle, insurance coverage, and clinical context (e.g., pregnancy, prior injection use, daily-dosing burden). Many patients begin on sublingual Suboxone for stabilization and transition to monthly Sublocade or weekly Brixadi after sustained recovery.

Buprenorphine Side Effects

Common buprenorphine side effects include:

  • Headache and dizziness
  • Nausea and vomiting, especially during induction
  • Constipation and insomnia
  • Excessive sweating
  • Mouth numbness or oral discomfort from sublingual formulations

More serious side effects may include respiratory depression (particularly when combined with benzodiazepines or alcohol), liver problems, and allergic reactions. For most patients, side effects are mild and resolve within one to two weeks. The benefits in preventing relapse and overdose death significantly outweigh the risks.

Buprenorphine Dosage and Induction

Treatment begins with an induction phase where the patient must be in mild to moderate opioid withdrawal. Common induction doses range from 2 mg to 8 mg on the first day, with increases over the following days. Most patients stabilize on 8 mg to 24 mg per day, with 16 mg being the most commonly prescribed dose. Research suggests doses of 16 mg or higher are associated with better retention and outcomes. Dosage should always be adjusted under medical supervision.

Buprenorphine/Naloxone Combination

Many buprenorphine formulations include naloxone as an abuse deterrent. When taken sublingually as directed, naloxone has very low bioavailability and produces no clinical effect. However, if someone attempts to inject the medication, the naloxone component becomes fully active and triggers severe withdrawal. This design discourages injection misuse while having no impact on patients who take the medication correctly. The combination is the standard first-line formulation for opioid addiction treatment.

Suboxone: Sublingual Buprenorphine

Suboxone is the most recognized brand name for buprenorphine-naloxone and is most commonly dispensed as a sublingual film (Suboxone strips) that dissolves under the tongue. Suboxone has transformed opioid treatment by enabling millions of patients to receive effective pharmacotherapy in outpatient settings without the daily clinic visits required by methadone programs.

Suboxone Side Effects

Commonly reported Suboxone side effects include headache, nausea, tongue or mouth irritation, constipation, insomnia, sweating, and decreased libido. The sublingual film can cause irritation or small sores inside the mouth — rotating placement between under the tongue and against the cheek helps minimize this. Patients should not eat, drink, or smoke while the film is dissolving.

Suboxone Strips: Film vs. Tablet

Suboxone strips (sublingual film) have largely replaced the original tablet form. The film dissolves more quickly (two to four minutes), provides more consistent absorption, and is harder to divert due to individual foil packaging. Generic buprenorphine-naloxone tablets are often less expensive and may be preferred for cost reasons. Both are therapeutically equivalent when taken as prescribed.

Suboxone Treatment Programs

Comprehensive Suboxone treatment typically includes three phases:

  • Induction: Initial dosing under medical supervision, requiring the patient to be in early withdrawal
  • Stabilization: Dose adjustment until cravings and withdrawal are minimal, usually one to two months
  • Maintenance: Stable dosing for an extended period — often a year or longer — combined with counseling and behavioral therapy

Evidence consistently shows that longer treatment durations are associated with better outcomes. Most addiction medicine experts recommend a minimum of one to two years of maintenance therapy.

Find a Suboxone Clinic Near You — OBOT & Telehealth Options

Finding a Suboxone clinic has become significantly easier since the federal government eliminated the X-waiver requirement in January 2023, meaning any provider with a standard DEA license can now prescribe Suboxone. Patients can search SAMHSA's treatment locator at findtreatment.gov or use our directory to locate nearby facilities that offer buprenorphine-based treatment.

Suboxone Doctors Near Me

Beyond SAMHSA's locator, many state health departments maintain directories of addiction treatment providers. Telehealth has dramatically expanded access — several platforms now offer virtual Suboxone consultations, which is especially valuable for patients in rural areas. When selecting a provider, look for those offering comprehensive treatment including counseling, not just medication prescriptions.

Suboxone Withdrawal and Tapering

Suboxone withdrawal can include muscle aches, anxiety, insomnia, nausea, sweating, and intense opioid cravings. A gradual, medically supervised taper is recommended — typically reducing the dose by 10 to 25 percent every one to four weeks. Slower tapers over several months produce fewer symptoms and lower relapse rates. There is no medically mandated time limit for Suboxone treatment, and many patients benefit from indefinite maintenance.

Suboxone vs Methadone

Suboxone can be prescribed in office settings and taken at home, carries lower overdose risk due to its ceiling effect, and offers greater scheduling flexibility. Methadone is a full agonist that may be more effective for severe, long-standing dependence but must be dispensed at licensed clinics with daily visits. Neither is inherently superior — the best choice keeps the patient in treatment. Some patients may also benefit from naltrexone, a non-opioid alternative.

Sublocade: Monthly Buprenorphine Injection

Sublocade delivers buprenorphine as a once-monthly subcutaneous injection in the abdominal area using the ATRIGEL delivery system, which forms a solid biodegradable depot that slowly releases medication. Patients must first stabilize on sublingual buprenorphine (8 mg+ daily) for at least seven days. Treatment typically begins with two 300 mg injections, followed by maintenance on 300 mg or 100 mg. Sublocade eliminates concerns about daily adherence, missed doses, and medication diversion.

Sublocade Side Effects

The most common Sublocade side effects are injection-site reactions (pain, itching, redness, or a noticeable lump), nausea, constipation, headache, and fatigue. The injection-site lump is normal and gradually diminishes as medication is absorbed. Patients should avoid rubbing or massaging the site. Elevated liver enzymes may also occur but are usually mild and transient.

Subutex: Buprenorphine Without Naloxone

Subutex was the original brand-name buprenorphine product. While the brand has been discontinued, generic buprenorphine-only tablets remain available. Buprenorphine monotherapy is typically reserved for pregnant patients (to avoid naloxone exposure to the fetus), patients with documented naloxone sensitivity, or sometimes during the induction phase before transitioning to the combination product.

Subutex vs Suboxone

The primary difference is the absence of naloxone in Subutex. Because Subutex lacks the abuse-deterrent naloxone component, it may carry slightly higher diversion risk, and many insurance formularies prioritize the combination as the default. Current clinical guidelines favor buprenorphine-only formulations primarily for pregnancy and naloxone sensitivity.

Zubsolv: Alternative Buprenorphine Brand

Zubsolv is a buprenorphine-naloxone sublingual tablet featuring a mint flavor and faster dissolution (under two minutes). Due to enhanced bioavailability, Zubsolv uses different dose strengths — a 5.7 mg/1.4 mg tablet equals a Suboxone 8 mg/2 mg dose. Zubsolv is available in multiple strengths for flexible dosing during both induction and maintenance.

Buprenorphine resources:

Find Buprenorphine (Suboxone) by State

Browse buprenorphine (suboxone) programs in states with the most treatment options.

Explore Related Options

Related conditions, treatment approaches, and levels of care.

Medically Reviewed Updated July 2026

Reviewed by licensed addiction specialists. Information reflects current clinical guidance.

Sources:SAMHSA·NIDA·CDC

Need immediate help? Call SAMHSA: 1-800-662-4357 (24/7, free)