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Updated: July 2026
Sources: SAMHSA, NIDA

Suboxone Clinic Near You: Buprenorphine Treatment for Opioid Addiction

Find a Suboxone clinic near you. Buprenorphine — sold under brand names Suboxone, Sublocade, Subutex, Zubsolv, and Brixadi — is the most-prescribed MAT for opioid use disorder. It is a partial mu-opioid agonist with a ceiling effect that dramatically reduces overdose risk vs. methadone. After the MAT Act of 2023 eliminated the X-waiver requirement, any licensed prescriber can prescribe buprenorphine in office-based settings (OBOT), via telehealth, or at retail pharmacies. Buprenorphine is a Schedule III controlled substance and is covered by Medicaid in all 50 states.

Found 7,145 treatment centers offering buprenorphine (suboxone) across the United States.

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Veterans Affairs Medical Center

Situated in Oklahoma City, OK, the Veterans Affairs Medical Center delivers a wide range of addiction rehabilitation services. This institution features inpatient detox programs and treatment, along with options for transitional housing. Emphasizing techniques such as 12-step support, anger management, and focused brief interventions, the center serves active duty service members and adult clients of all genders. It excels in addressing the needs of both adults and young adults who are in need of detoxification, substance misuse treatment, and transitional housing assistance. For those in search of a rehabilitation center tailored for veterans with diverse treatment alternatives, this facility merits your consideration.

Veterans Affairs Medical Center

The Veterans Affairs Medical Center in Salem, VA, is a leading facility providing extensive support for adults and young adults grappling with addiction and comorbid mental health challenges. They offer inpatient hospital detoxification and treatment, with a dedicated focus on active-duty military members. Through personalized strategies like 12-step facilitation and anger management, the center ensures each patient receives tailored care. This commitment to quality rehabilitation for adult men, women, young adults, and active-duty service members makes it a distinguished choice for recovery.

Veterans Affairs Medical Center

Situated in Omaha, NE, the Veterans Affairs Medical Center provides an extensive array of services for those in need of detoxification and treatment for substance use disorders. The center focuses on delivering specialized assistance to adults facing co-occurring substance use and severe mental health challenges, as well as children grappling with significant emotional issues. Treatment options include inpatient detoxification and round-the-clock hospital care, employing methodologies such as 12-step facilitation, anger management strategies, and brief intervention techniques. Programs are specifically designed for active-duty military members, as well as adult men and women. Committed to offering top-notch, personalized care, this facility serves adults, seniors, and young adults across all genders, ensuring that the distinct needs of each individual are addressed.

Veterans Affairs Medical Center

The Veterans Affairs Medical Center in Washington, DC provides an array of rehabilitation services aimed at adults and young adults facing substance use challenges along with concurrent mental health issues. This center features tailored treatment options for adult males, survivors of sexual trauma, and individuals struggling with both persistent pain and substance use. Prioritizing high-quality care, it delivers hospital-based detoxification and treatment around the clock, ensuring comprehensive inpatient support. The treatment methods employed include twelve-step programs, anger management strategies, and brief intervention techniques. The center is inclusive, welcoming both men and women into a nurturing setting designed to aid them in their journey towards recovery and enhanced well-being.

Veterans Affairs Medical Center

The Veterans Affairs Medical Center in San Francisco, CA, provides extensive rehabilitation programs designed for adults and older adults. Their expertise lies in treating addiction, substance abuse, and dual diagnoses. They offer various levels of care, including intensive outpatient, standard outpatient, and outpatient detoxification. The center employs therapeutic strategies like anger management, brief intervention, and cognitive behavioral therapy. They serve both men and women, with specific considerations for survivors of intimate partner violence. The Veterans Affairs Medical Center distinguishes itself through its dedication to individual patient needs and high-quality treatment.

Veterans Affairs Miami Medical Ctr

Situated in Miami, FL, the Veterans Affairs Miami Medical Ctr delivers extensive rehabilitation services designed for both adults and teens dealing with substance use issues alongside mental health challenges. This center offers inpatient detoxification and treatment programs emphasizing 12-step approaches, anger management, and short intervention strategies. It features specialized programs for adult women, individuals who have faced trauma, and clients with dual diagnoses of mental health and substance use disorders. Committed to providing high-quality care, the center accommodates both men and women, developing personalized treatment plans that cater to the distinct requirements of each patient.

Veterans Alcoholic Rehab Prog (VARP)

Situated in San Bernardino, California, Veterans Alcoholic Rehab Prog (VARP) delivers extensive substance use treatment tailored for adult male veterans. This center emphasizes long-term residential services, incorporating 12-step facilitation, anger management, and cognitive behavioral therapy into its approach. VARP is particularly adept at addressing co-occurring substance use disorders alongside serious mental health conditions in adults, as well as emotional challenges in children. The program is designed for adult men, encompassing both seniors and younger individuals, especially those with a history of trauma or sexual abuse. Offering transitional housing and a nurturing atmosphere, VARP is committed to delivering exceptional care and guidance for those seeking recovery.

Veterans Alcoholic Rehab Prog (VARP)

Veterans Alcoholic Rehab Prog (VARP) located in San Bernardino, CA, delivers an extensive array of services aimed at adult male individuals facing challenges with substance abuse disorders. The center features options for long-term residential, short-term residential, and transitional living, integrating methods such as 12-step facilitation, anger management, and cognitive behavioral therapy. VARP is particularly focused on addressing co-occurring substance use disorders alongside significant mental health challenges, including trauma and experiences of sexual abuse. Programs are customized for adult men, seniors, and young adults, ensuring personalized support. By emphasizing high-quality and specialized care, this center commits to aiding clients throughout their recovery process.

Veterans Alcoholic Rehab Prog (VARP)

Situated in San Bernardino, CA, the Veterans Alcoholic Rehab Prog (VARP) specializes in substance use treatment for women, seniors, and young adults. This center creates a secure space for long-term residential care, emphasizing 12-step facilitation, anger management, and cognitive behavioral therapy. It features transitional housing options and assistance for those dealing with both substance use and significant mental health challenges. Distinct services are available for adult women, survivors of sexual abuse, and individuals coping with trauma. VARP is committed to delivering exceptional care for those in need of thorough rehabilitation services in a nurturing and gender-sensitive setting.

Veterans Alcoholic Rehab Prog (VARP)

Veterans Alcoholic Rehab Prog (VARP) in San Bernardino, CA, delivers targeted addiction recovery services for adult men, featuring transitional and halfway house accommodations. They provide varied program lengths including long-term, short-term, and 24-hour residential care, employing proven methods such as 12-step facilitation, anger management, and cognitive behavioral therapy. Specializing in assisting clients with a history of trauma or sexual abuse, VARP supports adults, seniors, and young adults managing dual diagnoses of substance use and mental health disorders. The center distinguishes itself through its dedication to high-quality, individualized support for male veterans on their path to sobriety.

Veterans Alcoholic Rehab Prog (VARP)

Veterans Alcoholic Rehab Prog (VARP) in San Bernardino, CA, provides extensive addiction treatment services for adult women, older adults, and younger individuals. This center is adept at addressing dual diagnoses involving substance abuse and significant mental health conditions. VARP emphasizes extended residential stays, incorporating 12-step programs, anger control techniques, and cognitive behavioral therapy. The program also serves adult women with a history of sexual abuse or trauma. VARP offers transitional living, halfway housing, and sober living residences to foster a nurturing recovery setting. Clients can anticipate superior care and customized treatment strategies.

Veterans Alcoholic Rehab Prog (VARP)

Veterans Alcoholic Rehab Prog (VARP) located in San Bernardino, CA, provides premier treatment for substance use disorders and transitional housing specifically for women. This facility is adept at addressing both substance use and significant mental health challenges, offering various options including long-term care, short-term programs, and around-the-clock residential services. Emphasizing approaches such as 12-step support, anger management techniques, and cognitive behavioral strategies, VARP serves adult women, seniors, and younger adults alike. Additionally, specialized programs aimed at helping survivors of sexual abuse and trauma distinguish this center from others. Those in search of thorough, gender-specific treatment provided by knowledgeable professionals will receive outstanding assistance at VARP.

Veterans Alcoholic Rehab Prog (VARP)

Veterans Alcoholic Rehab Prog (VARP) in San Bernardino, CA, provides extensive, tailored care for those addressing addiction and needing a supportive place to live. They offer varied residential stays including extended, brief, and around-the-clock options. Their treatment methods include 12-step support, strategies for managing anger, and cognitive behavioral techniques. VARP supports adult women struggling with addiction and co-occurring severe mental health conditions, with particular attention given to individuals with a history of sexual abuse or trauma. This center is dedicated to meeting the specific requirements of its female clientele, delivering excellent support for adults, older adults, and young adults on their path to recovery.

Veterans Alcoholic Rehab Prog (VARP)

Situated in San Bernardino, CA, the Veterans Alcoholic Rehab Prog (VARP) provides an extensive array of specialized services. This center focuses on substance abuse treatment, transitional living options, and sober housing. Emphasizing care for individuals facing both substance use disorders and significant mental health challenges, the program is designed for adults experiencing emotional difficulties. VARP features both long-term and short-term residential programs, integrating approaches such as 12-step support, anger management, and cognitive behavioral therapy. Notable offerings include specialized programs for adult women, those with trauma backgrounds, and individuals who have suffered from sexual abuse. This women-focused facility accommodates adults, seniors, and young adults, ensuring personalized and compassionate care.

Veterans Alcoholic Rehab Prog (VARP)

Veterans Alcoholic Rehab Prog (VARP) in San Bernardino, CA, provides specialized substance abuse treatment and temporary housing for adult male veterans. They offer diverse program lengths, including extended, brief, and immediate residential care, emphasizing 12-step recovery, emotional regulation techniques, and cognitive restructuring. VARP is particularly adept at addressing dual diagnoses involving addiction and severe mental health conditions in adult men. Their approach is uniquely tailored to veterans who have faced trauma or sexual assault, serving adult males across different age groups who are looking for effective, caring support.

Veterans Alcoholic Rehab Prog (VARP)

Veterans Alcoholic Rehab Prog (VARP) in San Bernardino, CA, delivers extensive substance abuse recovery services for adult males. This residential program emphasizes long-term stays, integrating proven therapeutic modalities such as 12-step programs, anger management, and cognitive behavioral techniques. VARP is particularly adept at addressing dual diagnoses, managing co-occurring substance use disorders and severe mental health conditions. Specialized interventions are available for individuals with histories of sexual abuse or trauma. Additionally, the center provides supportive transitional and sober living options. Catering to adult, senior, and young adult men, VARP is dedicated to offering superior care within a nurturing setting designed for restoration and lasting sobriety.

Veterans Alcoholic Rehab Prog (VARP)

Situated in San Bernardino, CA, the Veterans Alcoholic Rehab Prog (VARP) provides an extensive array of services aimed at adults and seniors in need of substance abuse rehabilitation and transitional living solutions. This center focuses on addressing both concurrent substance use disorders and significant mental health challenges in adults, as well as serious emotional issues in children. VARP offers a variety of treatment options including long-term, short-term, and round-the-clock residential care, employing evidence-based methods like 12-step programs, anger management strategies, and cognitive behavioral therapy. They also feature specialized programs designed for adult women, individuals who have faced sexual abuse, and those with trauma histories, making it a commendable choice for women seeking focused assistance and guidance.

Veterans Affairs Medical Center

Situated in Erie, PA, the Veterans Affairs Medical Center offers a wide range of addiction rehabilitation services specifically for veterans. The center provides hospital-based detox programs, round-the-clock care in a hospital setting, and intensive outpatient services. It focuses on addressing substance use disorders alongside mental health issues in both adults and children. Utilizing techniques such as brief interventions, cognitive behavioral therapy, and motivational incentives, the facility prioritizes personalized treatment for adult and young adult patients, regardless of gender. Additionally, veterans have access to specialized programs tailored to their distinct requirements, ensuring an environment conducive to high-quality, gender-sensitive care.

VICTA
Providence, RI

Situated in Providence, RI, "VICTA" stands out as an exceptional rehabilitation facility that provides a wide array of services. It focuses on detoxification, treatment for substance use disorders, as well as addressing co-occurring conditions related to substance use and significant mental health challenges in adults, along with serious emotional issues in children. The center offers intensive outpatient programs, outpatient services, and options for partial hospitalization. Emphasizing 12-step encouragement, anger management strategies, and short-term interventions, "VICTA" is designed for adolescents, adult males, and adult females. This facility is dedicated to serving individuals of all ages and backgrounds, aiming to deliver personalized, high-quality support to foster effective recovery paths.

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Situated in Blythe, California, Veterans Alcoholic Rehab Prog (VARP) specializes in addiction recovery for adult male veterans. The center offers extended residential services within a nurturing setting, complemented by transitional housing alternatives. Utilizing proven treatment modalities, including 12-step facilitation, anger management sessions, and cognitive behavioral therapy, the program addresses both substance use disorders and accompanying mental health issues. VARP specifically supports clients with histories of trauma or sexual abuse, creating a secure environment for recovery. With a dedicated focus on adult men, this facility delivers thorough care aimed at helping individuals reclaim their lives from addiction.

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Shrewsbury, MA

Veterans Inc, situated in Shrewsbury, MA, provides a wide array of services for substance use rehabilitation aimed at both adults and young adults. The center offers various options including intensive outpatient care, long-term residential treatment, and outpatient support for those facing concurrent mental health challenges. Veterans Inc has designed its programs to cater specifically to adult men, adult women, and those grappling with both substance use and mental health concerns, addressing the individual requirements of each person. By employing evidence-based strategies such as 12-step programs, anger management techniques, and brief interventions, this facility is committed to delivering top-notch support for all clients on their path to recovery.

Frequently Asked Questions

What is buprenorphine and how does it treat opioid addiction?
Buprenorphine is a partial opioid agonist medication approved by the FDA for treating opioid use disorder. It binds to the same receptors as heroin and fentanyl but produces a much weaker effect, reducing cravings and withdrawal symptoms without causing intense euphoria. Buprenorphine has a ceiling effect, meaning its opioid effects plateau at moderate doses, making it safer than methadone in terms of overdose risk.
What is the difference between Suboxone and Subutex?
Suboxone contains two active ingredients — buprenorphine and naloxone — while Subutex contains only buprenorphine without naloxone. The naloxone in Suboxone is included as an abuse deterrent; it remains inactive when taken sublingually as prescribed but triggers withdrawal if the medication is injected. Subutex is generally reserved for patients who cannot tolerate naloxone, such as pregnant women.
What is a Sublocade injection and how does it work?
Sublocade is a once-monthly injectable form of buprenorphine administered as a subcutaneous injection in the abdominal area. After injection, the medication forms a solid deposit under the skin that slowly releases buprenorphine over the course of a month. This eliminates daily dosing and removes the possibility of missed doses or medication diversion.
What are the common side effects of Suboxone?
Common Suboxone side effects include headache, nausea, constipation, insomnia, sweating, and mouth numbness or pain from sublingual administration. Some patients also experience dizziness, drowsiness, and blurred vision, particularly when starting treatment. Most side effects diminish within the first few weeks as the body adjusts. Patients should report difficulty breathing or signs of allergic reaction immediately.
What happens during Suboxone withdrawal?
Suboxone withdrawal occurs when a patient stops taking the medication abruptly after prolonged use, with symptoms including muscle aches, anxiety, insomnia, nausea, and irritability. A medically supervised taper is strongly recommended, typically reducing the dose by small increments over weeks or months. The risk of opioid relapse is significantly higher during unsupervised discontinuation.
How does Suboxone compare to methadone?
Suboxone and methadone are both effective for opioid use disorder but differ in key ways. Methadone is a full opioid agonist dispensed daily at licensed clinics, while Suboxone is a partial agonist that can be prescribed by qualified physicians and taken at home. Suboxone carries a lower overdose risk due to its ceiling effect and offers greater convenience, though methadone may be more appropriate for patients with severe, long-standing dependence.
How can I find a Suboxone clinic or doctor near me?
The most reliable way to find a Suboxone provider is through SAMHSA's online treatment locator at findtreatment.gov, which allows you to search by location and filter for buprenorphine providers. Many primary care offices, addiction treatment centers, and telehealth platforms now offer Suboxone prescriptions following the elimination of the federal X-waiver requirement in early 2023.
What is Zubsolv and how is it different from Suboxone?
Zubsolv is a brand-name buprenorphine and naloxone sublingual tablet that features a mint flavor and dissolves faster under the tongue than other options. Due to its higher bioavailability, Zubsolv uses different dosing strengths — a Zubsolv 5.7 mg/1.4 mg tablet is considered equivalent to a Suboxone 8 mg/2 mg dose. Patients switching between products should work closely with their prescriber for correct dose conversion.
Does Medicaid cover Suboxone treatment?
Yes — Medicaid covers buprenorphine (including Suboxone, Sublocade, Subutex, Zubsolv, and Brixadi) for opioid use disorder in all 50 states, as required by the SUPPORT Act of 2018. Medicaid is the largest single payer for MAT in the US. Coverage details vary by state — some require prior authorization or limit certain formulations. Many OBOT clinics accept Medicaid directly; telehealth Suboxone providers also bill Medicaid in most states. Bring your Medicaid card to your intake appointment.
Can I get Suboxone through telehealth?
Yes. After the MAT Act of 2023 permanently eliminated the X-waiver requirement, any licensed prescriber can prescribe Suboxone via telehealth in most states. The DEA also extended COVID-era telehealth flexibilities through at least 2025, allowing virtual Suboxone induction without a prior in-person visit. Several specialty platforms — Bicycle Health, Ophelia, Workit Health, Boulder Care — offer Medicaid-accepting telehealth Suboxone treatment. Telehealth has dramatically expanded access in rural and underserved areas with no nearby OBOT physicians.

About Buprenorphine (Suboxone)

Buprenorphine is classified as a partial opioid agonist, meaning it activates opioid receptors in the brain but to a much lesser degree than full agonists such as heroin, fentanyl, or oxycodone. This partial activation suppresses withdrawal symptoms and reduces cravings without producing dangerous respiratory depression or intense euphoria. Buprenorphine also has an unusually high binding affinity for the mu-opioid receptor, effectively blocking other opioids from attaching — providing a protective effect against relapse-related overdose.

How Buprenorphine Works

One of the defining features of buprenorphine is its ceiling effect — after a certain dose threshold, increasing the amount does not produce additional opioid effects. This dramatically reduces the risk of fatal overdose compared to methadone or illicit opioids. The ceiling effect, combined with its long duration of action (24 to 72 hours), makes buprenorphine one of the safest and most effective tools in medication-assisted treatment (MAT). Approved by the FDA in 2002, buprenorphine was a breakthrough because it could be prescribed in outpatient settings rather than requiring daily clinic visits.

Buprenorphine Brand Comparison: Suboxone, Subutex, Sublocade, Zubsolv, Brixadi

Buprenorphine is available under several FDA-approved brand names, each with distinct formulations, dosing schedules, and clinical use cases. The comparison below highlights the key differences:

BrandActive ingredientFormFrequencySettingFDA yearBest for
SuboxoneBuprenorphine + naloxoneSublingual film / tabletDailyOBOT, telehealth, retail pharmacy2002Most prescribed; naloxone deters injection misuse
SubutexBuprenorphine (alone)Sublingual tabletDailyOBOT2002Pregnancy; documented naloxone sensitivity
SublocadeBuprenorphine extended-releaseSubcutaneous injection (ATRIGEL depot)MonthlyClinic-administered2017No daily dosing; eliminates diversion risk
ZubsolvBuprenorphine + naloxoneSublingual tablet (higher bioavailability)DailyOBOT2013Faster dissolution; mint flavor; lower mg/dose
BrixadiBuprenorphine extended-releaseSubcutaneous injectionWeekly or monthlyClinic2023Newer alternative to Sublocade; weekly option for induction

All five medications are Schedule III controlled substances and equivalent in clinical efficacy at appropriate doses. The choice depends on adherence patterns, lifestyle, insurance coverage, and clinical context (e.g., pregnancy, prior injection use, daily-dosing burden). Many patients begin on sublingual Suboxone for stabilization and transition to monthly Sublocade or weekly Brixadi after sustained recovery.

Buprenorphine Side Effects

Common buprenorphine side effects include:

  • Headache and dizziness
  • Nausea and vomiting, especially during induction
  • Constipation and insomnia
  • Excessive sweating
  • Mouth numbness or oral discomfort from sublingual formulations

More serious side effects may include respiratory depression (particularly when combined with benzodiazepines or alcohol), liver problems, and allergic reactions. For most patients, side effects are mild and resolve within one to two weeks. The benefits in preventing relapse and overdose death significantly outweigh the risks.

Buprenorphine Dosage and Induction

Treatment begins with an induction phase where the patient must be in mild to moderate opioid withdrawal. Common induction doses range from 2 mg to 8 mg on the first day, with increases over the following days. Most patients stabilize on 8 mg to 24 mg per day, with 16 mg being the most commonly prescribed dose. Research suggests doses of 16 mg or higher are associated with better retention and outcomes. Dosage should always be adjusted under medical supervision.

Buprenorphine/Naloxone Combination

Many buprenorphine formulations include naloxone as an abuse deterrent. When taken sublingually as directed, naloxone has very low bioavailability and produces no clinical effect. However, if someone attempts to inject the medication, the naloxone component becomes fully active and triggers severe withdrawal. This design discourages injection misuse while having no impact on patients who take the medication correctly. The combination is the standard first-line formulation for opioid addiction treatment.

Suboxone: Sublingual Buprenorphine

Suboxone is the most recognized brand name for buprenorphine-naloxone and is most commonly dispensed as a sublingual film (Suboxone strips) that dissolves under the tongue. Suboxone has transformed opioid treatment by enabling millions of patients to receive effective pharmacotherapy in outpatient settings without the daily clinic visits required by methadone programs.

Suboxone Side Effects

Commonly reported Suboxone side effects include headache, nausea, tongue or mouth irritation, constipation, insomnia, sweating, and decreased libido. The sublingual film can cause irritation or small sores inside the mouth — rotating placement between under the tongue and against the cheek helps minimize this. Patients should not eat, drink, or smoke while the film is dissolving.

Suboxone Strips: Film vs. Tablet

Suboxone strips (sublingual film) have largely replaced the original tablet form. The film dissolves more quickly (two to four minutes), provides more consistent absorption, and is harder to divert due to individual foil packaging. Generic buprenorphine-naloxone tablets are often less expensive and may be preferred for cost reasons. Both are therapeutically equivalent when taken as prescribed.

Suboxone Treatment Programs

Comprehensive Suboxone treatment typically includes three phases:

  • Induction: Initial dosing under medical supervision, requiring the patient to be in early withdrawal
  • Stabilization: Dose adjustment until cravings and withdrawal are minimal, usually one to two months
  • Maintenance: Stable dosing for an extended period — often a year or longer — combined with counseling and behavioral therapy

Evidence consistently shows that longer treatment durations are associated with better outcomes. Most addiction medicine experts recommend a minimum of one to two years of maintenance therapy.

Find a Suboxone Clinic Near You — OBOT & Telehealth Options

Finding a Suboxone clinic has become significantly easier since the federal government eliminated the X-waiver requirement in January 2023, meaning any provider with a standard DEA license can now prescribe Suboxone. Patients can search SAMHSA's treatment locator at findtreatment.gov or use our directory to locate nearby facilities that offer buprenorphine-based treatment.

Suboxone Doctors Near Me

Beyond SAMHSA's locator, many state health departments maintain directories of addiction treatment providers. Telehealth has dramatically expanded access — several platforms now offer virtual Suboxone consultations, which is especially valuable for patients in rural areas. When selecting a provider, look for those offering comprehensive treatment including counseling, not just medication prescriptions.

Suboxone Withdrawal and Tapering

Suboxone withdrawal can include muscle aches, anxiety, insomnia, nausea, sweating, and intense opioid cravings. A gradual, medically supervised taper is recommended — typically reducing the dose by 10 to 25 percent every one to four weeks. Slower tapers over several months produce fewer symptoms and lower relapse rates. There is no medically mandated time limit for Suboxone treatment, and many patients benefit from indefinite maintenance.

Suboxone vs Methadone

Suboxone can be prescribed in office settings and taken at home, carries lower overdose risk due to its ceiling effect, and offers greater scheduling flexibility. Methadone is a full agonist that may be more effective for severe, long-standing dependence but must be dispensed at licensed clinics with daily visits. Neither is inherently superior — the best choice keeps the patient in treatment. Some patients may also benefit from naltrexone, a non-opioid alternative.

Sublocade: Monthly Buprenorphine Injection

Sublocade delivers buprenorphine as a once-monthly subcutaneous injection in the abdominal area using the ATRIGEL delivery system, which forms a solid biodegradable depot that slowly releases medication. Patients must first stabilize on sublingual buprenorphine (8 mg+ daily) for at least seven days. Treatment typically begins with two 300 mg injections, followed by maintenance on 300 mg or 100 mg. Sublocade eliminates concerns about daily adherence, missed doses, and medication diversion.

Sublocade Side Effects

The most common Sublocade side effects are injection-site reactions (pain, itching, redness, or a noticeable lump), nausea, constipation, headache, and fatigue. The injection-site lump is normal and gradually diminishes as medication is absorbed. Patients should avoid rubbing or massaging the site. Elevated liver enzymes may also occur but are usually mild and transient.

Subutex: Buprenorphine Without Naloxone

Subutex was the original brand-name buprenorphine product. While the brand has been discontinued, generic buprenorphine-only tablets remain available. Buprenorphine monotherapy is typically reserved for pregnant patients (to avoid naloxone exposure to the fetus), patients with documented naloxone sensitivity, or sometimes during the induction phase before transitioning to the combination product.

Subutex vs Suboxone

The primary difference is the absence of naloxone in Subutex. Because Subutex lacks the abuse-deterrent naloxone component, it may carry slightly higher diversion risk, and many insurance formularies prioritize the combination as the default. Current clinical guidelines favor buprenorphine-only formulations primarily for pregnancy and naloxone sensitivity.

Zubsolv: Alternative Buprenorphine Brand

Zubsolv is a buprenorphine-naloxone sublingual tablet featuring a mint flavor and faster dissolution (under two minutes). Due to enhanced bioavailability, Zubsolv uses different dose strengths — a 5.7 mg/1.4 mg tablet equals a Suboxone 8 mg/2 mg dose. Zubsolv is available in multiple strengths for flexible dosing during both induction and maintenance.

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Medically Reviewed Updated July 2026

Reviewed by licensed addiction specialists. Information reflects current clinical guidance.

Sources:SAMHSA·NIDA·CDC

Need immediate help? Call SAMHSA: 1-800-662-4357 (24/7, free)