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Medically Reviewed Content
Updated: May 2026
Sources: SAMHSA, NIDA

Suboxone Clinic Near You: Buprenorphine Treatment for Opioid Addiction

Find a Suboxone clinic near you. Buprenorphine — sold under brand names Suboxone, Sublocade, Subutex, Zubsolv, and Brixadi — is the most-prescribed MAT for opioid use disorder. It is a partial mu-opioid agonist with a ceiling effect that dramatically reduces overdose risk vs. methadone. After the MAT Act of 2023 eliminated the X-waiver requirement, any licensed prescriber can prescribe buprenorphine in office-based settings (OBOT), via telehealth, or at retail pharmacies. Buprenorphine is a Schedule III controlled substance and is covered by Medicaid in all 50 states.

Found 7,145 treatment centers offering buprenorphine (suboxone) across the United States.

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Volunteers of America (VOA) Alaska

VOA Alaska, situated in Anchorage, AK, delivers focused care for adults managing both substance use disorders and significant mental health challenges. Their services encompass intensive outpatient, outpatient day, and partial hospitalization programs, integrating therapeutic methods such as 12-step facilitation and anger management. The facility customizes its offerings for various age groups and genders, including adolescents, adult men, and women. VOA Alaska supports a broad demographic, including adults, children, adolescents, and young adults, with dedicated gender-specific treatment for males and females. Clients will experience effective, research-backed treatment within a nurturing and empathetic setting.

Volunteers of America (VOA)/Alaska

Nestled in Eagle River, Alaska, Volunteers of America (VOA)/Alaska offers a holistic approach to substance use recovery for adults and children facing concurrent serious mental health conditions. Their diverse program offerings include extended residential stays, outpatient services, and round-the-clock residential care. The center integrates therapeutic modalities such as anger management, brief intervention strategies, and cognitive behavioral therapy. VOA/Alaska also provides specialized support for adolescents, survivors of intimate partner violence, domestic violence, and sexual abuse. Catering to a broad demographic including adults, children and adolescents, and young adults of all genders, VOA/Alaska is committed to delivering personalized, superior care.

Volunteers of America Mid States

Volunteers of America Mid-States in Louisville, KY, provides extensive care for adults battling addiction. This center excels in addressing dual diagnoses, simultaneously treating substance abuse and significant mental health challenges in individuals of all ages. Their approach emphasizes 12-step principles, anger management, and short-term therapeutic strategies, delivered through intensive outpatient, extended residential, and standard outpatient services. Specialized programs are available for adult women, particularly those impacted by domestic violence and sexual assault. Catering to a broad demographic including adults, seniors, and younger adults, Volunteers of America Mid-States is dedicated to personalized recovery journeys for women.

Volunteers of America Mid States

Situated in Louisville, KY, Volunteers of America Mid States focuses on treating substance use issues and co-occurring disorders in both adults and children. The center features various programs, including long-term, short-term, and 24-hour residential care, employing evidence-based strategies like 12-step facilitation, cognitive behavioral therapy, and the Matrix Model. Special programs are available for adult women, as well as those who have experienced intimate partner violence, domestic violence, and sexual abuse. By prioritizing the needs of adult, senior, and young adult women, the facility ensures a nurturing and secure atmosphere conducive to healing and recovery. Discover exceptional support and tailored treatment options at Volunteers of America Mid States.

Volunteers of America OHIN

Situated in Indianapolis, IN, Volunteers of America OHIN delivers exceptional substance abuse treatment through a variety of specialized services. The center provides long-term residential, 24-hour residential, and short-term treatment options designed for adults, seniors, and young adults. Emphasizing 12-step facilitation, anger management, and brief intervention techniques, it is particularly dedicated to assisting women who have faced intimate partner violence or domestic abuse. Moreover, the facility offers specialized programs for active duty military members and adult women. Volunteers of America OHIN is committed to delivering comprehensive care and support for those pursuing recovery within a secure and supportive atmosphere.

Volusia County Comprehensive Trtr Ctr

Situated in Port Orange, FL, the Volusia County Comprehensive Trtr Ctr delivers extensive treatment solutions for substance use issues. This facility features outpatient options such as treatments involving methadone, buprenorphine, or naltrexone, along with standard outpatient services. The center is proficient in cognitive behavioral therapy, motivational interviewing, and counseling for substance use disorders. It also offers specialized programs designed for adult men, adult women, and pregnant or postpartum women, addressing the needs of a broad demographic. Catering to both men and women, as well as young adults, the center is committed to providing tailored care and support to every client. Discover exceptional care and evidence-based treatment methods at Volusia County Comprehensive Trtr Ctr.

Volunteers of America OHIN

Situated in Winchester, Indiana, Volunteers of America OHIN provides a wide range of substance abuse treatment and specialized support for those facing dual diagnoses involving severe mental health issues. The center offers multiple residential treatment options, which include long-term, short-term, and round-the-clock care. Utilizing evidence-based methods such as 12-step programs, anger management strategies, and brief interventions, the facility also features distinctive programs designed for adult women, as well as those who have experienced domestic violence, intimate partner violence, and sexual abuse. By concentrating on the needs of adult, senior, and young adult women, Volunteers of America OHIN ensures high-quality care that addresses the varied requirements of its clientele.

Volunteers of America Utah
Salt Lake City, UT

Volunteers of America Utah, located in Salt Lake City, delivers extensive substance abuse rehabilitation and focused support for those experiencing simultaneous mental health issues. The facility offers intensive outpatient care, outpatient options, and day programs based on proven methodologies such as cognitive behavioral therapy and anger management strategies. It features customized programs designed for adolescents as well as adult men and women, accommodating a variety of age groups and genders. By emphasizing short-term interventions and personalized treatment plans, the center provides effective care for individuals pursuing recovery from addiction and mental health difficulties.

Volunteers of America Northern Rockies

Situated in Cheyenne, WY, Volunteers of America Northern Rockies delivers comprehensive treatment programs for adults facing substance use challenges alongside serious mental health disorders, as well as support for children with emotional issues. The facility offers various levels of care including intensive outpatient services, outpatient therapy, and medication-assisted treatment with methadone, buprenorphine, or naltrexone. Emphasizing key areas such as anger management, brief intervention, and cognitive behavioral therapy, the center serves a diverse clientele including adolescents, adult males, and adult females. By providing tailored programs that meet the unique requirements of each individual, Volunteers of America Northern Rockies stands as a vital resource for those in search of compassionate and effective addiction recovery options.

Volunteers of America OHIN

Situated in Indianapolis, IN, Volunteers of America OHIN provides comprehensive substance use rehabilitation for adult males in a nurturing setting. This center features an array of treatment options, comprising long-term residential, 24-hour residential, and short-term residential programs. Employing targeted strategies such as 12-step facilitation, anger management, and brief intervention, the facility specifically addresses the needs of individuals affected by intimate partner and domestic violence. Specialized services are also offered for active duty military members. Aiming to assist adults, seniors, and younger adults, this center prioritizes effective recovery solutions tailored to the unique challenges faced by men dealing with substance use disorders.

Volunteers of America Dakotas

Volunteers of America Dakotas, situated in Sioux Falls, SD, delivers thorough addiction recovery programs for adults and older individuals. This location features intensive outpatient therapy, extended stay residential accommodations, and standard outpatient services. Dedicated tracks exist for teenagers, adult women, and individuals who have faced traumatic experiences, allowing for tailored support. Employing methods like 12-step guidance, emotional regulation techniques, and short-term counseling, the facility prioritizes personalized recovery plans. Volunteers of America Dakotas accepts all genders, providing effective rehabilitation in an understanding and caring setting.

Volunteers of America Northern Rockies

Volunteers of America Northern Rockies, situated in Torrington, WY, delivers exceptional rehabilitative support to adults and seniors facing challenges with addiction and co-occurring mental health concerns. The center features robust intensive outpatient programs, standard outpatient services, and tailored medication-assisted treatment options, including methadone, buprenorphine, or naltrexone. Emphasizing approaches like anger management, brief intervention, and cognitive behavioral therapy, this establishment serves adult men, adult women, and young people. Through its individualized programming, Volunteers of America Northern Rockies guarantees high-quality care for all clients, establishing itself as a vital institution for individuals pursuing thorough and successful recovery from substance use disorders.

Volunteers of America Northern Rockies

Situated in Wheatland, WY, Volunteers of America Northern Rockies specializes in treating adults with substance use disorders alongside significant mental health issues and emotional challenges in children. This center offers both intensive outpatient and outpatient services, incorporating treatments such as methadone/buprenorphine or naltrexone. Emphasizing techniques like anger management, brief interventions, and cognitive behavioral therapy, the facility serves adult men, women, and teenagers. It accommodates both adults and elderly clients, providing customized support for male and female individuals. Volunteers of America Northern Rockies is committed to delivering high-quality care and personalized treatment to facilitate recovery and enhance overall wellness.

Volunteers of America Northern Rockies

Situated in Laramie, WY, Volunteers of America Northern Rockies delivers extensive treatment options for adults facing substance use issues alongside serious mental health conditions. The facility offers a variety of services including intensive outpatient programs, general outpatient care, and specialized treatments with methadone/buprenorphine or naltrexone. It focuses on areas such as anger management, brief interventions, and cognitive behavioral therapy. With programs designed for adolescents as well as adult men and women, this rehabilitation center serves a diverse clientele. Committed to offering top-notch support and care, Volunteers of America Northern Rockies assists adults and seniors of all genders on their journey to recovery from substance use disorders and mental health difficulties.

Walden Clinic
Walden, NY

Situated in Walden, NY, Walden Clinic is a dedicated facility providing specialized outpatient services for individuals grappling with substance use disorders, co-occurring severe mental health conditions in adults, and emotional challenges in children. The clinic employs a range of therapeutic modalities, including medication-assisted treatment with methadone, buprenorphine, or naltrexone, alongside general outpatient therapy. They also implement evidence-based interventions like cognitive behavioral therapy and contingency management, tailored to each person's needs. Walden Clinic distinguishes itself with distinct programs catering to adult men, adult women, and those affected by intimate partner violence or domestic abuse. The center extends its support to both adults and the younger population of children and adolescents, serving all genders. Walden Clinic is recognized for its thorough offerings, customized treatment strategies, and a strong dedication to delivering high-quality care.

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Situated in Camden, NJ, Volunteers of America Delaware Valley delivers extensive treatment for substance use issues aimed at both adults and young adults. This center features intensive outpatient, outpatient, and standard outpatient services. The approach combines multiple methods, including 12-step facilitation, anger management, and brief interventions to assist individuals in their recovery process. There are specialized programs for adult men, adult women, and those who have undergone trauma. Emphasizing high-quality care, this facility serves both male and female clients, fostering a welcoming and inclusive atmosphere for everyone seeking help with addiction.

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Volunteers of America Mid States in Manchester, KY, is a dedicated facility providing extensive rehabilitation for adult women dealing with substance use disorders and co-occurring severe mental health challenges. They offer a range of residential programs including long-term, short-term, and 24-hour care, employing proven therapeutic methods like 12-step facilitation, cognitive behavioral therapy, and the Matrix Model. The center has particular expertise in assisting individuals with histories of intimate partner violence, domestic violence, and sexual abuse. Serving adults, seniors, and young adults, their services are tailored for women's unique needs. Volunteers of America Mid States is committed to delivering exceptional, personalized support throughout the recovery process.

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Situated in Cheyenne, WY, Volunteers of America Northern Rockies delivers targeted rehabilitation services for adult males affected by substance use disorders. This center features long-term residential options, which encompass detox and transitional housing, while emphasizing 12-step programs and anger management techniques. It also offers specialized programs for individuals who have faced sexual abuse or traumatic experiences. With a commitment to high-quality care, the center caters to adult, senior, and young adult male clients. For individuals looking for a nurturing atmosphere to combat addiction and tackle root problems, this facility offers extensive treatment in a residential framework.

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Volunteers of America Northern Rockies, situated in Cheyenne, WY, delivers tailored outpatient programs for adults and youth facing substance use and co-occurring mental health challenges. Their services include medication-assisted treatment with methadone, buprenorphine, or naltrexone, complemented by therapeutic modalities such as anger management, cognitive behavioral therapy, and brief intervention. This center prioritizes individuals with dual diagnoses, serving a diverse clientele including adults and seniors. Volunteers of America Northern Rockies is committed to providing excellent and individualized recovery support.

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Situated in Portland, Oregon, Volunteers of America provides extensive substance abuse treatment tailored for adult men who are also facing significant mental health challenges. The center offers a range of programs, including long-term, short-term, and residential options that incorporate 12-step methodologies, anger management strategies, and brief intervention techniques. There are specialized programs available for active duty military members, men, and those who have encountered domestic violence. Focusing on adult, senior, and younger adult males, this facility is committed to delivering exceptional care within a nurturing setting, positioning itself as a premier option for individuals in search of effective rehabilitation in the Portland region.

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Situated in Winston Salem, NC, Wake Forest Baptist Health delivers extensive addiction recovery services for both adults and young adults. The facility specializes in detoxification, substance abuse treatment, and addressing co-occurring mental health issues. Available treatment modalities include intensive outpatient programs, outpatient detox, and various outpatient therapies. Prioritizing approaches such as 12-step facilitation, cognitive behavioral therapy, and motivational interviewing, this center serves adult men and women facing co-occurring challenges. With customized programs designed for diverse age groups and genders, the center promotes personalized care and support, highlighting the importance of effective treatment and sustainable recovery.

Frequently Asked Questions

What is buprenorphine and how does it treat opioid addiction?
Buprenorphine is a partial opioid agonist medication approved by the FDA for treating opioid use disorder. It binds to the same receptors as heroin and fentanyl but produces a much weaker effect, reducing cravings and withdrawal symptoms without causing intense euphoria. Buprenorphine has a ceiling effect, meaning its opioid effects plateau at moderate doses, making it safer than methadone in terms of overdose risk.
What is the difference between Suboxone and Subutex?
Suboxone contains two active ingredients — buprenorphine and naloxone — while Subutex contains only buprenorphine without naloxone. The naloxone in Suboxone is included as an abuse deterrent; it remains inactive when taken sublingually as prescribed but triggers withdrawal if the medication is injected. Subutex is generally reserved for patients who cannot tolerate naloxone, such as pregnant women.
What is a Sublocade injection and how does it work?
Sublocade is a once-monthly injectable form of buprenorphine administered as a subcutaneous injection in the abdominal area. After injection, the medication forms a solid deposit under the skin that slowly releases buprenorphine over the course of a month. This eliminates daily dosing and removes the possibility of missed doses or medication diversion.
What are the common side effects of Suboxone?
Common Suboxone side effects include headache, nausea, constipation, insomnia, sweating, and mouth numbness or pain from sublingual administration. Some patients also experience dizziness, drowsiness, and blurred vision, particularly when starting treatment. Most side effects diminish within the first few weeks as the body adjusts. Patients should report difficulty breathing or signs of allergic reaction immediately.
What happens during Suboxone withdrawal?
Suboxone withdrawal occurs when a patient stops taking the medication abruptly after prolonged use, with symptoms including muscle aches, anxiety, insomnia, nausea, and irritability. A medically supervised taper is strongly recommended, typically reducing the dose by small increments over weeks or months. The risk of opioid relapse is significantly higher during unsupervised discontinuation.
How does Suboxone compare to methadone?
Suboxone and methadone are both effective for opioid use disorder but differ in key ways. Methadone is a full opioid agonist dispensed daily at licensed clinics, while Suboxone is a partial agonist that can be prescribed by qualified physicians and taken at home. Suboxone carries a lower overdose risk due to its ceiling effect and offers greater convenience, though methadone may be more appropriate for patients with severe, long-standing dependence.
How can I find a Suboxone clinic or doctor near me?
The most reliable way to find a Suboxone provider is through SAMHSA's online treatment locator at findtreatment.gov, which allows you to search by location and filter for buprenorphine providers. Many primary care offices, addiction treatment centers, and telehealth platforms now offer Suboxone prescriptions following the elimination of the federal X-waiver requirement in early 2023.
What is Zubsolv and how is it different from Suboxone?
Zubsolv is a brand-name buprenorphine and naloxone sublingual tablet that features a mint flavor and dissolves faster under the tongue than other options. Due to its higher bioavailability, Zubsolv uses different dosing strengths — a Zubsolv 5.7 mg/1.4 mg tablet is considered equivalent to a Suboxone 8 mg/2 mg dose. Patients switching between products should work closely with their prescriber for correct dose conversion.
Does Medicaid cover Suboxone treatment?
Yes — Medicaid covers buprenorphine (including Suboxone, Sublocade, Subutex, Zubsolv, and Brixadi) for opioid use disorder in all 50 states, as required by the SUPPORT Act of 2018. Medicaid is the largest single payer for MAT in the US. Coverage details vary by state — some require prior authorization or limit certain formulations. Many OBOT clinics accept Medicaid directly; telehealth Suboxone providers also bill Medicaid in most states. Bring your Medicaid card to your intake appointment.
Can I get Suboxone through telehealth?
Yes. After the MAT Act of 2023 permanently eliminated the X-waiver requirement, any licensed prescriber can prescribe Suboxone via telehealth in most states. The DEA also extended COVID-era telehealth flexibilities through at least 2025, allowing virtual Suboxone induction without a prior in-person visit. Several specialty platforms — Bicycle Health, Ophelia, Workit Health, Boulder Care — offer Medicaid-accepting telehealth Suboxone treatment. Telehealth has dramatically expanded access in rural and underserved areas with no nearby OBOT physicians.

About Buprenorphine (Suboxone)

Buprenorphine is classified as a partial opioid agonist, meaning it activates opioid receptors in the brain but to a much lesser degree than full agonists such as heroin, fentanyl, or oxycodone. This partial activation suppresses withdrawal symptoms and reduces cravings without producing dangerous respiratory depression or intense euphoria. Buprenorphine also has an unusually high binding affinity for the mu-opioid receptor, effectively blocking other opioids from attaching — providing a protective effect against relapse-related overdose.

How Buprenorphine Works

One of the defining features of buprenorphine is its ceiling effect — after a certain dose threshold, increasing the amount does not produce additional opioid effects. This dramatically reduces the risk of fatal overdose compared to methadone or illicit opioids. The ceiling effect, combined with its long duration of action (24 to 72 hours), makes buprenorphine one of the safest and most effective tools in medication-assisted treatment (MAT). Approved by the FDA in 2002, buprenorphine was a breakthrough because it could be prescribed in outpatient settings rather than requiring daily clinic visits.

Buprenorphine Brand Comparison: Suboxone, Subutex, Sublocade, Zubsolv, Brixadi

Buprenorphine is available under several FDA-approved brand names, each with distinct formulations, dosing schedules, and clinical use cases. The comparison below highlights the key differences:

BrandActive ingredientFormFrequencySettingFDA yearBest for
SuboxoneBuprenorphine + naloxoneSublingual film / tabletDailyOBOT, telehealth, retail pharmacy2002Most prescribed; naloxone deters injection misuse
SubutexBuprenorphine (alone)Sublingual tabletDailyOBOT2002Pregnancy; documented naloxone sensitivity
SublocadeBuprenorphine extended-releaseSubcutaneous injection (ATRIGEL depot)MonthlyClinic-administered2017No daily dosing; eliminates diversion risk
ZubsolvBuprenorphine + naloxoneSublingual tablet (higher bioavailability)DailyOBOT2013Faster dissolution; mint flavor; lower mg/dose
BrixadiBuprenorphine extended-releaseSubcutaneous injectionWeekly or monthlyClinic2023Newer alternative to Sublocade; weekly option for induction

All five medications are Schedule III controlled substances and equivalent in clinical efficacy at appropriate doses. The choice depends on adherence patterns, lifestyle, insurance coverage, and clinical context (e.g., pregnancy, prior injection use, daily-dosing burden). Many patients begin on sublingual Suboxone for stabilization and transition to monthly Sublocade or weekly Brixadi after sustained recovery.

Buprenorphine Side Effects

Common buprenorphine side effects include:

  • Headache and dizziness
  • Nausea and vomiting, especially during induction
  • Constipation and insomnia
  • Excessive sweating
  • Mouth numbness or oral discomfort from sublingual formulations

More serious side effects may include respiratory depression (particularly when combined with benzodiazepines or alcohol), liver problems, and allergic reactions. For most patients, side effects are mild and resolve within one to two weeks. The benefits in preventing relapse and overdose death significantly outweigh the risks.

Buprenorphine Dosage and Induction

Treatment begins with an induction phase where the patient must be in mild to moderate opioid withdrawal. Common induction doses range from 2 mg to 8 mg on the first day, with increases over the following days. Most patients stabilize on 8 mg to 24 mg per day, with 16 mg being the most commonly prescribed dose. Research suggests doses of 16 mg or higher are associated with better retention and outcomes. Dosage should always be adjusted under medical supervision.

Buprenorphine/Naloxone Combination

Many buprenorphine formulations include naloxone as an abuse deterrent. When taken sublingually as directed, naloxone has very low bioavailability and produces no clinical effect. However, if someone attempts to inject the medication, the naloxone component becomes fully active and triggers severe withdrawal. This design discourages injection misuse while having no impact on patients who take the medication correctly. The combination is the standard first-line formulation for opioid addiction treatment.

Suboxone: Sublingual Buprenorphine

Suboxone is the most recognized brand name for buprenorphine-naloxone and is most commonly dispensed as a sublingual film (Suboxone strips) that dissolves under the tongue. Suboxone has transformed opioid treatment by enabling millions of patients to receive effective pharmacotherapy in outpatient settings without the daily clinic visits required by methadone programs.

Suboxone Side Effects

Commonly reported Suboxone side effects include headache, nausea, tongue or mouth irritation, constipation, insomnia, sweating, and decreased libido. The sublingual film can cause irritation or small sores inside the mouth — rotating placement between under the tongue and against the cheek helps minimize this. Patients should not eat, drink, or smoke while the film is dissolving.

Suboxone Strips: Film vs. Tablet

Suboxone strips (sublingual film) have largely replaced the original tablet form. The film dissolves more quickly (two to four minutes), provides more consistent absorption, and is harder to divert due to individual foil packaging. Generic buprenorphine-naloxone tablets are often less expensive and may be preferred for cost reasons. Both are therapeutically equivalent when taken as prescribed.

Suboxone Treatment Programs

Comprehensive Suboxone treatment typically includes three phases:

  • Induction: Initial dosing under medical supervision, requiring the patient to be in early withdrawal
  • Stabilization: Dose adjustment until cravings and withdrawal are minimal, usually one to two months
  • Maintenance: Stable dosing for an extended period — often a year or longer — combined with counseling and behavioral therapy

Evidence consistently shows that longer treatment durations are associated with better outcomes. Most addiction medicine experts recommend a minimum of one to two years of maintenance therapy.

Find a Suboxone Clinic Near You — OBOT & Telehealth Options

Finding a Suboxone clinic has become significantly easier since the federal government eliminated the X-waiver requirement in January 2023, meaning any provider with a standard DEA license can now prescribe Suboxone. Patients can search SAMHSA's treatment locator at findtreatment.gov or use our directory to locate nearby facilities that offer buprenorphine-based treatment.

Suboxone Doctors Near Me

Beyond SAMHSA's locator, many state health departments maintain directories of addiction treatment providers. Telehealth has dramatically expanded access — several platforms now offer virtual Suboxone consultations, which is especially valuable for patients in rural areas. When selecting a provider, look for those offering comprehensive treatment including counseling, not just medication prescriptions.

Suboxone Withdrawal and Tapering

Suboxone withdrawal can include muscle aches, anxiety, insomnia, nausea, sweating, and intense opioid cravings. A gradual, medically supervised taper is recommended — typically reducing the dose by 10 to 25 percent every one to four weeks. Slower tapers over several months produce fewer symptoms and lower relapse rates. There is no medically mandated time limit for Suboxone treatment, and many patients benefit from indefinite maintenance.

Suboxone vs Methadone

Suboxone can be prescribed in office settings and taken at home, carries lower overdose risk due to its ceiling effect, and offers greater scheduling flexibility. Methadone is a full agonist that may be more effective for severe, long-standing dependence but must be dispensed at licensed clinics with daily visits. Neither is inherently superior — the best choice keeps the patient in treatment. Some patients may also benefit from naltrexone, a non-opioid alternative.

Sublocade: Monthly Buprenorphine Injection

Sublocade delivers buprenorphine as a once-monthly subcutaneous injection in the abdominal area using the ATRIGEL delivery system, which forms a solid biodegradable depot that slowly releases medication. Patients must first stabilize on sublingual buprenorphine (8 mg+ daily) for at least seven days. Treatment typically begins with two 300 mg injections, followed by maintenance on 300 mg or 100 mg. Sublocade eliminates concerns about daily adherence, missed doses, and medication diversion.

Sublocade Side Effects

The most common Sublocade side effects are injection-site reactions (pain, itching, redness, or a noticeable lump), nausea, constipation, headache, and fatigue. The injection-site lump is normal and gradually diminishes as medication is absorbed. Patients should avoid rubbing or massaging the site. Elevated liver enzymes may also occur but are usually mild and transient.

Subutex: Buprenorphine Without Naloxone

Subutex was the original brand-name buprenorphine product. While the brand has been discontinued, generic buprenorphine-only tablets remain available. Buprenorphine monotherapy is typically reserved for pregnant patients (to avoid naloxone exposure to the fetus), patients with documented naloxone sensitivity, or sometimes during the induction phase before transitioning to the combination product.

Subutex vs Suboxone

The primary difference is the absence of naloxone in Subutex. Because Subutex lacks the abuse-deterrent naloxone component, it may carry slightly higher diversion risk, and many insurance formularies prioritize the combination as the default. Current clinical guidelines favor buprenorphine-only formulations primarily for pregnancy and naloxone sensitivity.

Zubsolv: Alternative Buprenorphine Brand

Zubsolv is a buprenorphine-naloxone sublingual tablet featuring a mint flavor and faster dissolution (under two minutes). Due to enhanced bioavailability, Zubsolv uses different dose strengths — a 5.7 mg/1.4 mg tablet equals a Suboxone 8 mg/2 mg dose. Zubsolv is available in multiple strengths for flexible dosing during both induction and maintenance.

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Medically Reviewed Updated May 2026

Reviewed by licensed addiction specialists. Information reflects current clinical guidance.

Sources:SAMHSA·NIDA·CDC

Need immediate help? Call SAMHSA: 1-800-662-4357 (24/7, free)