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Updated: May 2026
Sources: SAMHSA, NIDA

Suboxone Clinic Near You: Buprenorphine Treatment for Opioid Addiction

Find a Suboxone clinic near you. Buprenorphine — sold under brand names Suboxone, Sublocade, Subutex, Zubsolv, and Brixadi — is the most-prescribed MAT for opioid use disorder. It is a partial mu-opioid agonist with a ceiling effect that dramatically reduces overdose risk vs. methadone. After the MAT Act of 2023 eliminated the X-waiver requirement, any licensed prescriber can prescribe buprenorphine in office-based settings (OBOT), via telehealth, or at retail pharmacies. Buprenorphine is a Schedule III controlled substance and is covered by Medicaid in all 50 states.

Found 7,145 treatment centers offering buprenorphine (suboxone) across the United States.

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Willapa Behavioral Health and Wellness

Willapa Behavioral Health and Wellness, situated in Raymond, WA, offers extensive support for individuals grappling with addiction and co-occurring mental health challenges, serving both younger and adult populations. Their treatment options include structured intensive outpatient care, standard outpatient services, and medication-assisted treatment using methadone, buprenorphine, or naltrexone. Employing evidence-based methods such as anger management, motivational interviewing, and cognitive behavioral therapy, they personalize recovery plans. The center also provides dedicated support for those affected by intimate partner violence, domestic abuse, and legal system involvement. Willapa Behavioral Health and Wellness is committed to providing compassionate and effective care to adults and seniors of all backgrounds on their journey to wellness.

William Bill Kling
Fort Lauderdale, FL

The William Bill Kling Rehabilitation Center, situated in Fort Lauderdale, FL, specializes in providing treatment for detoxification, substance abuse, and co-occurring disorders for both adults and children. Offering a range of outpatient services such as detox programs, methadone and buprenorphine therapy, and a variety of therapeutic methods including 12-step facilitation and anger management, this center addresses the specific needs of adult men and women, seniors, and individuals who have faced intimate partner violence. It emphasizes personalized care for all clients, striving for excellence in treatment through short intervention strategies. For those in search of comprehensive and empathetic rehabilitation options, this center is committed to facilitating your path to recovery.

William J McCord
Orangeburg, SC

Situated in Orangeburg, SC, the William J McCord Rehabilitation Center specializes in delivering extensive support for those facing challenges related to substance abuse and accompanying mental health issues. This center offers targeted treatment options for adults dealing with severe mental health disorders, as well as support for children experiencing emotional difficulties and teenagers in need of assistance. Emphasizing evidence-based techniques such as cognitive behavioral therapy and motivational interviewing, the center also provides tailored programs aimed at managing anger. With services including hospital inpatient detox and around-the-clock care, this facility accommodates both male and female patients of various ages. Anticipate exceptional care and customized treatment strategies at the William J McCord Rehabilitation Center.

William S Middleton Veterans Hosp

Situated in Madison, WI, the William S Middleton Veterans Hosp presents an extensive array of treatment solutions for those striving to overcome substance abuse challenges. This facility delivers inpatient detoxification and treatment services, along with transitional housing and sober living assistance. Emphasizing 12-step programs, anger management, and brief intervention techniques, the center serves adult men and women, including younger adults. Tailored programs are also offered for individuals who have faced trauma and those dealing with co-occurring mental health issues. The center's gender-specific treatment model ensures that each individual receives customized care and support, highlighting a dedication to high-quality and effective rehabilitation services.

Williamsburg Place
Williamsburg, VA

Situated in Williamsburg, VA, Williamsburg Place delivers an extensive array of services for addiction recovery. The center specializes in detoxification and treatment for substance use, offering options such as residential detox, 24/7 residential care, and short-term residential programs. Emphasizing 12-step facilitation, anger management, and brief intervention strategies, this facility serves adult men and women, including those in active military service. Customized programs for both young adults and older adults guarantee individualized attention. Williamsburg Place is distinguished by its dedication to high-quality care and specialized treatment plans, making it a leading choice for those in need of effective and compassionate addiction support.

Williamson Comprehensive Treatment Ctr

Williamson Comprehensive Treatment Ctr, situated in Williamson, WV, provides extensive outpatient care for adults and young adults struggling with substance use disorders. Their approach incorporates 12-step facilitation, anger management, and brief intervention strategies. The facility serves adult men and women, including pregnant and postpartum individuals, offering tailored support for both genders. Williamson Comprehensive Treatment Ctr's outpatient programs utilizing methadone, buprenorphine, or naltrexone are individualized to ensure each patient receives effective treatment and dedicated assistance in their recovery process.

Willows at Red Oak Recovery

Willows at Red Oak Recovery in Fletcher, NC, delivers targeted treatment for adult women struggling with addiction and co-occurring severe mental health conditions. Their offerings include intensive outpatient, extended residential stays, and outpatient care, all customized for adult women with a history of intimate partner abuse. The center employs 12-step facilitation, anger management techniques, and cognitive behavioral therapy to deliver holistic support in a secure and nurturing setting. Catering to a diverse age range from seniors to young adults, Willows at Red Oak Recovery is distinguished by its high-caliber treatment and specific care for its female clientele.

Wilmington Treatment Center

Wilmington Treatment Center, situated in Wilmington, NC, delivers extensive rehabilitation options for both adults and young adults facing challenges with substance abuse and related mental health issues. This center features tailored programs for active duty military personnel, as well as separate provisions for adult men and women. It offers hospital-level inpatient detox services and treatment, employing methodologies such as the 12-step approach and anger management techniques. Prioritizing personalized care and using evidence-based methods like brief interventions, the center ensures high-quality care for all clients. If you or someone you care about is looking for reliable and compassionate addiction treatment, Wilmington Treatment Center is committed to guiding you toward a successful recovery.

Windmill Wellness Ranch

At Windmill Wellness Ranch in Canyon Lake, TX, we provide an all-encompassing suite of addiction recovery programs, encompassing detox, substance abuse therapy, temporary housing, and sober living options. Our facility offers inpatient medical detoxification and treatment, with tailored programs designed for active military members, adult men, and women. Employing proven therapeutic methods such as 12-step support, emotional regulation techniques, and cognitive behavioral therapy, we serve individuals of all ages, from youth to adults. Our commitment to high-quality care and personalized treatment strategies makes Windmill Wellness Ranch a reliable choice for individuals pursuing successful rehabilitation in a nurturing setting.

Winston Salem Comprehensive Trt Ctr

Situated in Winston Salem, NC, Winston Salem Comprehensive Trt Ctr delivers extensive substance use treatment programs tailored for both adults and young adults. The center offers outpatient services, which encompass outpatient methadone/buprenorphine or naltrexone therapies, standard outpatient treatment, and specialized programs designed for adult men, women, and pregnant or postpartum women. Emphasizing evidence-based methodologies like brief intervention, cognitive behavioral therapy, and motivational incentives, the facility serves male and female clients who are seeking high-quality assistance for their addiction challenges. Winston Salem Comprehensive Trt Ctr is committed to providing impactful and individualized treatment to help individuals navigate their recovery journey.

WisHope Recovery Center

WisHope Recovery Center, situated in Waukesha, WI, provides a wide array of services aimed at treating addiction for both adults and young adults. This establishment specializes in detoxification, treatment for substance use disorders, and distinctive programs for those facing both substance use issues and significant mental health challenges. WisHope Recovery Center customizes its treatment options, which include intensive outpatient, long-term residential, and various outpatient services, to align with the specific needs of each individual. The center utilizes a blend of methodologies, such as 12-step programs, anger management techniques, and brief interventions, to facilitate recovery. Furthermore, there are targeted programs available for active military members, as well as for adult men and women. Committed to providing high-quality care, WisHope Recovery Center aims to assist individuals on their journey to sustained sobriety.

Wilmot Family Health

Wilmot Family Health, situated in Tucson, Arizona, specializes in outpatient treatment for substance use for both adults and children who are simultaneously facing significant mental health challenges. The center employs various therapeutic techniques, including anger management and cognitive behavioral therapy, to deliver effective care through consistent outpatient appointments. Customized programs are designed for diverse groups, including active duty military members, men and women of all ages, and seniors. Emphasizing personalized care, the center cultivates a nurturing atmosphere for individuals committed to addressing substance use issues and mental health difficulties.

Williamson Health and Wellness Center

The Williamson Health and Wellness Center in Williamson, WV, provides targeted outpatient care for individuals struggling with substance use disorders and co-occurring mental health challenges. They also support children with serious emotional disturbances. Their approach emphasizes personalized treatment plans, incorporating techniques such as anger management, brief interventions, and cognitive behavioral therapy. Programs are designed to meet the specific needs of adults and seniors, serving both men and women. Services include outpatient medication-assisted treatment (methadone/buprenorphine or naltrexone) alongside standard outpatient therapy. The Williamson Health and Wellness Center is dedicated to delivering high-quality, compassionate rehabilitation services in a nurturing setting.

Wisdom Traditions Counseling Services

Situated in Anchorage, AK, Wisdom Traditions Counseling Services delivers a wide range of detoxification and substance abuse rehabilitation programs. The center features intensive outpatient treatment, standard outpatient services, as well as outpatient day treatment or partial hospitalization programs. Emphasizing 12-step methods, anger management, and brief intervention strategies, this facility serves adult men and women, including those in active military service. Catering to both adults and young adults across all genders, Wisdom Traditions Counseling Services is committed to providing high-quality care and individualized support for those pursuing recovery from addiction.

Willow Tree Recovery
Pleasant Grove, UT

Situated in Pleasant Grove, UT, Willow Tree Recovery is a prominent rehabilitation facility focused on addressing substance use issues. The center offers a variety of programs, including both long-term and short-term residential options, as well as around-the-clock support, catering to both adult males and females. What sets Willow Tree Recovery apart is its customized treatment methods, which encompass 12-step facilitation, anger management, and cognitive behavioral therapy. Additionally, the center is equipped to assist clients dealing with both mental health and substance use disorders, ensuring a holistic treatment approach. With an emphasis on high-quality, personalized care, Willow Tree Recovery is committed to guiding clients towards sustainable recovery.

Wilmington Mental Health

Situated in Wilmington, NC, Wilmington Mental Health is dedicated to offering a variety of outpatient programs aimed at addressing substance abuse and co-existing mental health issues in both adults and children. The center is equipped to provide customized treatment for specific groups, including military personnel, teenagers, and adult males. The therapeutic methods employed include cognitive behavioral therapy, anger management, and brief intervention strategies. Prioritizing high-quality treatment, this facility offers outpatient options for methadone/buprenorphine and naltrexone, alongside standard outpatient care. Wilmington Mental Health is committed to delivering thorough and efficient rehabilitation services to those tackling addiction and mental health struggles, catering to both men and women.

Willowbrooke at Tanner

Willowbrooke at Tanner in Carrollton, GA, provides thorough and caring support for individuals facing addiction and related mental health concerns. The center specializes in treating both adults and young people grappling with substance use disorders and dual diagnoses. Through various levels of care, such as intensive outpatient, standard outpatient, and day treatment programs, they employ proven therapeutic methods. These include techniques like anger management, cognitive behavioral therapy, and brief intervention strategies. Willowbrooke at Tanner caters to the unique needs of adolescents and those experiencing co-occurring mental health conditions, offering gender-inclusive programs. Rely on their skilled professionals to support your journey toward sustained recovery and enhanced health.

Willowbrooke at Tanner

Situated in Villa Rica, GA, Willowbrooke at Tanner is an all-encompassing rehabilitation facility that delivers focused treatment options for detox, substance abuse, and concurrent mental health challenges in both adults and children. The center offers inpatient hospital services, featuring round-the-clock care, and employs proven techniques such as cognitive behavioral therapy and anger management strategies. Willowbrooke at Tanner is notable for its customized programs designed specifically for teenagers and those facing dual diagnoses. Committed to delivering high-quality care, this center supports both male and female clients, fostering a nurturing space for recovery and wellness.

Windham Center
Bellows Falls, VT

Windham Center, situated in Bellows Falls, VT, delivers thorough care for adults and children facing addiction, substance abuse, and concurrent mental health concerns. This establishment provides inpatient hospital detoxification and treatment, featuring distinct programs for individuals with dual diagnoses. Utilizing proven methods such as 12-step support, anger management strategies, and brief intervention, Windham Center tailors its approach to meet each client's unique needs. Dedicated to high standards and personalized recovery plans, the center supports individuals of all genders, offering a nurturing setting for those pursuing healing from addiction and mental health struggles.

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Willapa Behavioral Health and Wellness, located in Montesano, WA, specializes in comprehensive treatment for substance use disorders and provides targeted support for individuals facing co-occurring mental health challenges. The center offers a variety of programs, including intensive outpatient care, outpatient services, and treatment with methadone/buprenorphine or naltrexone, all designed to meet the unique needs of each client. Emphasizing techniques such as anger management, brief intervention, and cognitive behavioral therapy, this facility adopts a holistic approach to facilitate recovery. Additionally, it features specialized programs for those affected by intimate partner violence, domestic abuse, and individuals within the criminal justice system. Catering to adults and seniors across all genders, this center ensures high-quality care within a nurturing atmosphere.

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Willow House 820 Residential, situated in Westons Mills, NY, provides extended residential treatment for substance use aimed at both adults and young adults. The center employs tailored care methods, including 12-step facilitation, cognitive behavioral therapy, and anger management. It features specialized programs designed for adult men and women, as well as individuals who have faced domestic or intimate partner violence. With an emphasis on gender-specific treatment, Willow House 820 Residential guarantees personalized care for all clients. At this facility, individuals can expect thorough and empathetic support for their addiction recovery in a nurturing residential environment.

Frequently Asked Questions

What is buprenorphine and how does it treat opioid addiction?
Buprenorphine is a partial opioid agonist medication approved by the FDA for treating opioid use disorder. It binds to the same receptors as heroin and fentanyl but produces a much weaker effect, reducing cravings and withdrawal symptoms without causing intense euphoria. Buprenorphine has a ceiling effect, meaning its opioid effects plateau at moderate doses, making it safer than methadone in terms of overdose risk.
What is the difference between Suboxone and Subutex?
Suboxone contains two active ingredients — buprenorphine and naloxone — while Subutex contains only buprenorphine without naloxone. The naloxone in Suboxone is included as an abuse deterrent; it remains inactive when taken sublingually as prescribed but triggers withdrawal if the medication is injected. Subutex is generally reserved for patients who cannot tolerate naloxone, such as pregnant women.
What is a Sublocade injection and how does it work?
Sublocade is a once-monthly injectable form of buprenorphine administered as a subcutaneous injection in the abdominal area. After injection, the medication forms a solid deposit under the skin that slowly releases buprenorphine over the course of a month. This eliminates daily dosing and removes the possibility of missed doses or medication diversion.
What are the common side effects of Suboxone?
Common Suboxone side effects include headache, nausea, constipation, insomnia, sweating, and mouth numbness or pain from sublingual administration. Some patients also experience dizziness, drowsiness, and blurred vision, particularly when starting treatment. Most side effects diminish within the first few weeks as the body adjusts. Patients should report difficulty breathing or signs of allergic reaction immediately.
What happens during Suboxone withdrawal?
Suboxone withdrawal occurs when a patient stops taking the medication abruptly after prolonged use, with symptoms including muscle aches, anxiety, insomnia, nausea, and irritability. A medically supervised taper is strongly recommended, typically reducing the dose by small increments over weeks or months. The risk of opioid relapse is significantly higher during unsupervised discontinuation.
How does Suboxone compare to methadone?
Suboxone and methadone are both effective for opioid use disorder but differ in key ways. Methadone is a full opioid agonist dispensed daily at licensed clinics, while Suboxone is a partial agonist that can be prescribed by qualified physicians and taken at home. Suboxone carries a lower overdose risk due to its ceiling effect and offers greater convenience, though methadone may be more appropriate for patients with severe, long-standing dependence.
How can I find a Suboxone clinic or doctor near me?
The most reliable way to find a Suboxone provider is through SAMHSA's online treatment locator at findtreatment.gov, which allows you to search by location and filter for buprenorphine providers. Many primary care offices, addiction treatment centers, and telehealth platforms now offer Suboxone prescriptions following the elimination of the federal X-waiver requirement in early 2023.
What is Zubsolv and how is it different from Suboxone?
Zubsolv is a brand-name buprenorphine and naloxone sublingual tablet that features a mint flavor and dissolves faster under the tongue than other options. Due to its higher bioavailability, Zubsolv uses different dosing strengths — a Zubsolv 5.7 mg/1.4 mg tablet is considered equivalent to a Suboxone 8 mg/2 mg dose. Patients switching between products should work closely with their prescriber for correct dose conversion.
Does Medicaid cover Suboxone treatment?
Yes — Medicaid covers buprenorphine (including Suboxone, Sublocade, Subutex, Zubsolv, and Brixadi) for opioid use disorder in all 50 states, as required by the SUPPORT Act of 2018. Medicaid is the largest single payer for MAT in the US. Coverage details vary by state — some require prior authorization or limit certain formulations. Many OBOT clinics accept Medicaid directly; telehealth Suboxone providers also bill Medicaid in most states. Bring your Medicaid card to your intake appointment.
Can I get Suboxone through telehealth?
Yes. After the MAT Act of 2023 permanently eliminated the X-waiver requirement, any licensed prescriber can prescribe Suboxone via telehealth in most states. The DEA also extended COVID-era telehealth flexibilities through at least 2025, allowing virtual Suboxone induction without a prior in-person visit. Several specialty platforms — Bicycle Health, Ophelia, Workit Health, Boulder Care — offer Medicaid-accepting telehealth Suboxone treatment. Telehealth has dramatically expanded access in rural and underserved areas with no nearby OBOT physicians.

About Buprenorphine (Suboxone)

Buprenorphine is classified as a partial opioid agonist, meaning it activates opioid receptors in the brain but to a much lesser degree than full agonists such as heroin, fentanyl, or oxycodone. This partial activation suppresses withdrawal symptoms and reduces cravings without producing dangerous respiratory depression or intense euphoria. Buprenorphine also has an unusually high binding affinity for the mu-opioid receptor, effectively blocking other opioids from attaching — providing a protective effect against relapse-related overdose.

How Buprenorphine Works

One of the defining features of buprenorphine is its ceiling effect — after a certain dose threshold, increasing the amount does not produce additional opioid effects. This dramatically reduces the risk of fatal overdose compared to methadone or illicit opioids. The ceiling effect, combined with its long duration of action (24 to 72 hours), makes buprenorphine one of the safest and most effective tools in medication-assisted treatment (MAT). Approved by the FDA in 2002, buprenorphine was a breakthrough because it could be prescribed in outpatient settings rather than requiring daily clinic visits.

Buprenorphine Brand Comparison: Suboxone, Subutex, Sublocade, Zubsolv, Brixadi

Buprenorphine is available under several FDA-approved brand names, each with distinct formulations, dosing schedules, and clinical use cases. The comparison below highlights the key differences:

BrandActive ingredientFormFrequencySettingFDA yearBest for
SuboxoneBuprenorphine + naloxoneSublingual film / tabletDailyOBOT, telehealth, retail pharmacy2002Most prescribed; naloxone deters injection misuse
SubutexBuprenorphine (alone)Sublingual tabletDailyOBOT2002Pregnancy; documented naloxone sensitivity
SublocadeBuprenorphine extended-releaseSubcutaneous injection (ATRIGEL depot)MonthlyClinic-administered2017No daily dosing; eliminates diversion risk
ZubsolvBuprenorphine + naloxoneSublingual tablet (higher bioavailability)DailyOBOT2013Faster dissolution; mint flavor; lower mg/dose
BrixadiBuprenorphine extended-releaseSubcutaneous injectionWeekly or monthlyClinic2023Newer alternative to Sublocade; weekly option for induction

All five medications are Schedule III controlled substances and equivalent in clinical efficacy at appropriate doses. The choice depends on adherence patterns, lifestyle, insurance coverage, and clinical context (e.g., pregnancy, prior injection use, daily-dosing burden). Many patients begin on sublingual Suboxone for stabilization and transition to monthly Sublocade or weekly Brixadi after sustained recovery.

Buprenorphine Side Effects

Common buprenorphine side effects include:

  • Headache and dizziness
  • Nausea and vomiting, especially during induction
  • Constipation and insomnia
  • Excessive sweating
  • Mouth numbness or oral discomfort from sublingual formulations

More serious side effects may include respiratory depression (particularly when combined with benzodiazepines or alcohol), liver problems, and allergic reactions. For most patients, side effects are mild and resolve within one to two weeks. The benefits in preventing relapse and overdose death significantly outweigh the risks.

Buprenorphine Dosage and Induction

Treatment begins with an induction phase where the patient must be in mild to moderate opioid withdrawal. Common induction doses range from 2 mg to 8 mg on the first day, with increases over the following days. Most patients stabilize on 8 mg to 24 mg per day, with 16 mg being the most commonly prescribed dose. Research suggests doses of 16 mg or higher are associated with better retention and outcomes. Dosage should always be adjusted under medical supervision.

Buprenorphine/Naloxone Combination

Many buprenorphine formulations include naloxone as an abuse deterrent. When taken sublingually as directed, naloxone has very low bioavailability and produces no clinical effect. However, if someone attempts to inject the medication, the naloxone component becomes fully active and triggers severe withdrawal. This design discourages injection misuse while having no impact on patients who take the medication correctly. The combination is the standard first-line formulation for opioid addiction treatment.

Suboxone: Sublingual Buprenorphine

Suboxone is the most recognized brand name for buprenorphine-naloxone and is most commonly dispensed as a sublingual film (Suboxone strips) that dissolves under the tongue. Suboxone has transformed opioid treatment by enabling millions of patients to receive effective pharmacotherapy in outpatient settings without the daily clinic visits required by methadone programs.

Suboxone Side Effects

Commonly reported Suboxone side effects include headache, nausea, tongue or mouth irritation, constipation, insomnia, sweating, and decreased libido. The sublingual film can cause irritation or small sores inside the mouth — rotating placement between under the tongue and against the cheek helps minimize this. Patients should not eat, drink, or smoke while the film is dissolving.

Suboxone Strips: Film vs. Tablet

Suboxone strips (sublingual film) have largely replaced the original tablet form. The film dissolves more quickly (two to four minutes), provides more consistent absorption, and is harder to divert due to individual foil packaging. Generic buprenorphine-naloxone tablets are often less expensive and may be preferred for cost reasons. Both are therapeutically equivalent when taken as prescribed.

Suboxone Treatment Programs

Comprehensive Suboxone treatment typically includes three phases:

  • Induction: Initial dosing under medical supervision, requiring the patient to be in early withdrawal
  • Stabilization: Dose adjustment until cravings and withdrawal are minimal, usually one to two months
  • Maintenance: Stable dosing for an extended period — often a year or longer — combined with counseling and behavioral therapy

Evidence consistently shows that longer treatment durations are associated with better outcomes. Most addiction medicine experts recommend a minimum of one to two years of maintenance therapy.

Find a Suboxone Clinic Near You — OBOT & Telehealth Options

Finding a Suboxone clinic has become significantly easier since the federal government eliminated the X-waiver requirement in January 2023, meaning any provider with a standard DEA license can now prescribe Suboxone. Patients can search SAMHSA's treatment locator at findtreatment.gov or use our directory to locate nearby facilities that offer buprenorphine-based treatment.

Suboxone Doctors Near Me

Beyond SAMHSA's locator, many state health departments maintain directories of addiction treatment providers. Telehealth has dramatically expanded access — several platforms now offer virtual Suboxone consultations, which is especially valuable for patients in rural areas. When selecting a provider, look for those offering comprehensive treatment including counseling, not just medication prescriptions.

Suboxone Withdrawal and Tapering

Suboxone withdrawal can include muscle aches, anxiety, insomnia, nausea, sweating, and intense opioid cravings. A gradual, medically supervised taper is recommended — typically reducing the dose by 10 to 25 percent every one to four weeks. Slower tapers over several months produce fewer symptoms and lower relapse rates. There is no medically mandated time limit for Suboxone treatment, and many patients benefit from indefinite maintenance.

Suboxone vs Methadone

Suboxone can be prescribed in office settings and taken at home, carries lower overdose risk due to its ceiling effect, and offers greater scheduling flexibility. Methadone is a full agonist that may be more effective for severe, long-standing dependence but must be dispensed at licensed clinics with daily visits. Neither is inherently superior — the best choice keeps the patient in treatment. Some patients may also benefit from naltrexone, a non-opioid alternative.

Sublocade: Monthly Buprenorphine Injection

Sublocade delivers buprenorphine as a once-monthly subcutaneous injection in the abdominal area using the ATRIGEL delivery system, which forms a solid biodegradable depot that slowly releases medication. Patients must first stabilize on sublingual buprenorphine (8 mg+ daily) for at least seven days. Treatment typically begins with two 300 mg injections, followed by maintenance on 300 mg or 100 mg. Sublocade eliminates concerns about daily adherence, missed doses, and medication diversion.

Sublocade Side Effects

The most common Sublocade side effects are injection-site reactions (pain, itching, redness, or a noticeable lump), nausea, constipation, headache, and fatigue. The injection-site lump is normal and gradually diminishes as medication is absorbed. Patients should avoid rubbing or massaging the site. Elevated liver enzymes may also occur but are usually mild and transient.

Subutex: Buprenorphine Without Naloxone

Subutex was the original brand-name buprenorphine product. While the brand has been discontinued, generic buprenorphine-only tablets remain available. Buprenorphine monotherapy is typically reserved for pregnant patients (to avoid naloxone exposure to the fetus), patients with documented naloxone sensitivity, or sometimes during the induction phase before transitioning to the combination product.

Subutex vs Suboxone

The primary difference is the absence of naloxone in Subutex. Because Subutex lacks the abuse-deterrent naloxone component, it may carry slightly higher diversion risk, and many insurance formularies prioritize the combination as the default. Current clinical guidelines favor buprenorphine-only formulations primarily for pregnancy and naloxone sensitivity.

Zubsolv: Alternative Buprenorphine Brand

Zubsolv is a buprenorphine-naloxone sublingual tablet featuring a mint flavor and faster dissolution (under two minutes). Due to enhanced bioavailability, Zubsolv uses different dose strengths — a 5.7 mg/1.4 mg tablet equals a Suboxone 8 mg/2 mg dose. Zubsolv is available in multiple strengths for flexible dosing during both induction and maintenance.

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Medically Reviewed Updated May 2026

Reviewed by licensed addiction specialists. Information reflects current clinical guidance.

Sources:SAMHSA·NIDA·CDC

Need immediate help? Call SAMHSA: 1-800-662-4357 (24/7, free)