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Medically Reviewed Content
Updated: July 2026
Sources: SAMHSA, NIDA

Suboxone Clinic Near You: Buprenorphine Treatment for Opioid Addiction

Find a Suboxone clinic near you. Buprenorphine — sold under brand names Suboxone, Sublocade, Subutex, Zubsolv, and Brixadi — is the most-prescribed MAT for opioid use disorder. It is a partial mu-opioid agonist with a ceiling effect that dramatically reduces overdose risk vs. methadone. After the MAT Act of 2023 eliminated the X-waiver requirement, any licensed prescriber can prescribe buprenorphine in office-based settings (OBOT), via telehealth, or at retail pharmacies. Buprenorphine is a Schedule III controlled substance and is covered by Medicaid in all 50 states.

Found 7,145 treatment centers offering buprenorphine (suboxone) across the United States.

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Catholic Charities
Hartford, CT

Catholic Charities in Hartford, CT, delivers a full spectrum of substance abuse recovery services for adults managing co-occurring severe mental health challenges and children with significant emotional difficulties. The center employs evidence-based methods like anger management, brief intervention, and cognitive behavioral therapy within its intensive outpatient, outpatient, and standard outpatient programs. Tailored programs are available for teens, adult males, and adult females, addressing the needs of various age demographics and genders. Patients receive personalized, superior care, establishing Catholic Charities as a dependable resource for effective and empathetic recovery support.

Catholic Charities/Rockville Centre

Situated in Hampton Bays, NY, Catholic Charities/Rockville Centre specializes in comprehensive treatment for adults and young adults dealing with substance use issues, particularly those with co-occurring serious mental health conditions or emotional challenges. The center offers outpatient services, including treatments with methadone, buprenorphine, or naltrexone, along with standard outpatient care. Emphasizing techniques such as 12-step facilitation, brief interventions, and cognitive behavioral therapy, this facility serves active duty military members as well as adult men and women. Catholic Charities/Rockville Centre provides customized programs for both genders, ensuring high-quality support for individuals on their path to recovery.

Catholic Community Services

Catholic Community Services located in Seattle, WA provides outpatient treatment for substance use disorders in adults, including those who may also experience significant mental health challenges or emotional issues. This center offers a variety of treatment options, such as outpatient care utilizing methadone, buprenorphine, or naltrexone, alongside standard outpatient services. Emphasizing personalized care, the facility employs evidence-based methods like cognitive behavioral therapy, motivational interviewing, and brief interventions. Customized programs are available for both adults and young adults, accommodating the needs of all genders. For individuals in search of effective addiction treatment that prioritizes individualized support, this center could be an excellent choice.

Cazenovia Manor
Buffalo, NY

Cazenovia Manor, located in Buffalo, NY, is a premier rehabilitation facility dedicated to providing long-term residential treatment for adult men dealing with substance use issues. The center delivers extensive support for individuals who also face mental health challenges concurrently. By implementing proven strategies such as anger management, cognitive behavioral therapy, and motivational incentives, the program serves diverse age groups, including adults, seniors, and young adults in pursuit of recovery. Cazenovia Manor is distinguished by its commitment to addressing both substance use problems and significant mental health disorders, fostering an environment conducive to comprehensive healing. Renowned for its exemplary care and tailored programs, this center serves as a guiding light for those embarking on their path to sobriety.

CDT Service Corporation

CDT Service Corporation, situated in Loomis, CA, delivers a complete spectrum of addiction recovery support. This establishment features inpatient hospital detox and therapy, emphasizing 12-step integration and emotional regulation techniques. Tailored programs are available for adult men and women, as well as individuals with a history of sexual trauma. The center provides supervised housing and specialized assistance for young adults and adults, guaranteeing personalized attention for everyone. CDT Service Corporation is recognized for its excellent support and customized strategies, establishing it as a premier destination for those pursuing successful and empathetic recovery programs.

CBI Encompass Health Services

CBI Encompass Health Services located in Page, AZ, is a facility devoted to providing extensive treatment for addiction. It focuses on detoxification and various support services for substance use disorders, particularly for adults facing co-occurring mental health challenges and significant emotional issues in children. The center offers a range of services, including intensive outpatient programs, general outpatient care, and detoxification. Emphasizing methods like cognitive behavioral therapy, anger management, and brief intervention, clients receive tailored support that meets their individual requirements. Additionally, specific programs address the needs of those who have suffered from trauma, intimate partner violence, and combined mental health and substance use issues. Catering to adults and seniors of diverse genders, this facility prioritizes high-quality and gender-sensitive rehabilitation care.

Catholic Charities of Miami

Catholic Charities of Miami, situated in Miami, FL, provides extensive addiction recovery services for adults and adolescents. This center excels in addressing dual diagnoses, treating individuals with both substance abuse and severe mental health conditions, alongside children experiencing significant emotional challenges. Offering extended residential stays, daily outpatient services, and medication-assisted treatment including methadone, buprenorphine, or naltrexone, the facility tailors each recovery journey with methods like 12-step encouragement, emotional regulation training, and short-term counseling. Special therapeutic offerings are available for those with trauma histories and co-occurring conditions. Emphasizing superior support, Catholic Charities of Miami serves both men and women in pursuit of successful recovery.

Catholic Charities Family and Comm

Situated in Rochester, NY, Catholic Charities Family and Comm delivers an extensive array of addiction treatment services. The center features intensive outpatient programs, standard outpatient services, and options for methadone, buprenorphine, or naltrexone therapy. Emphasizing strategies like anger management, brief interventions, and cognitive behavioral therapy, this facility is designed for adult males and females, including those who have faced intimate partner or domestic violence. Catering to both adults and young adults, this center prioritizes personalized care and assistance for individuals striving to break free from addiction.

Catholic Charities Family and Comm

Nestled in Rochester, NY, Catholic Charities Family and Comm is a dedicated facility providing targeted substance use interventions for adults facing concurrent serious mental health conditions, as well as for children with emotional challenges. Their services encompass intensive outpatient, standard outpatient, and medication-assisted treatment options including methadone, buprenorphine, or naltrexone. Employing therapeutic modalities such as anger management, brief intervention strategies, and cognitive behavioral therapy, the center supports adult men and women, including survivors of intimate partner violence. Catering to a broad age range, from adolescents to seniors, and offering gender-specific programming, Catholic Charities Family and Comm is committed to delivering holistic care that prioritizes individual recovery journeys and optimal treatment results.

Catholic Charities
Portland, ME

Catholic Charities, located in Portland, ME, presents a thorough array of substance use rehabilitation services aimed at both adults and younger individuals experiencing concurrent mental health issues. This center offers intensive outpatient and standard outpatient programs, which feature treatment alternatives such as methadone/buprenorphine and naltrexone. Emphasizing 12-step methodologies, anger management techniques, and brief intervention strategies, the facility customizes its treatment approaches to align with the unique needs of each client. Specialized programs are available for adult men and women, as well as those who have faced trauma. By catering to both male and female clients, Catholic Charities commits to delivering exceptional care in a nurturing and understanding atmosphere for individuals pursuing recovery.

Catholic Charities Neighborhood Servs

Situated in Brooklyn, NY, Catholic Charities Neighborhood Servs delivers a wide array of substance abuse treatment programs, with a particular emphasis on addressing co-occurring substance use disorders and severe mental health issues among adults, as well as emotional challenges in children. The facility offers various levels of care, including intensive outpatient, outpatient, and medication-assisted treatment featuring methadone, buprenorphine, or naltrexone. Committed to approaches like 12-step facilitation, anger management, and brief interventions, the center serves adolescents and adult men and women alike. Catering to individuals of all genders, the center prioritizes personalized care to meet diverse needs effectively.

Catholic Charities of Utica/Rome

Catholic Charities of Utica/Rome, situated in Utica, NY, provides extended residential care for adult women battling substance use disorders within a nurturing atmosphere. This establishment offers interim lodging, structured recovery housing, and sober living arrangements for individuals managing both mental health and substance dependency issues. The program employs proven therapeutic methods, including techniques for managing anger, cognitive restructuring, and motivational strategies, to adeptly meet each person's unique challenges. Emphasizing support for those with a history of trauma, the center serves adults, older adults, and younger adults in search of all-encompassing support within a women-only environment. Catholic Charities of Utica/Rome is committed to delivering superior rehabilitative services to foster enduring recovery.

CDHS Inc
Arlington, TX

CDHS Inc, located in Arlington, TX, specializes in a wide range of substance use treatment programs designed for both adults and young adults. The facility offers outpatient options, including treatments with methadone, buprenorphine, or naltrexone, along with standard outpatient care. With an emphasis on cognitive behavioral therapy, relapse prevention strategies, and counseling specific to substance use disorders, CDHS Inc crafts its treatment plans to meet the unique needs of each client. The center is committed to an individualized method, accepting both men and women who are in need of high-quality addiction treatment. If you are seeking tailored and effective rehabilitation support, this center is focused on aiding you in your recovery path.

CBI Encompass Health Services

CBI Encompass Health Services, located in Littlefield, AZ, specializes in comprehensive rehabilitation programs designed for adults and seniors dealing with substance use disorders alongside mental health challenges. The center features intensive outpatient treatment, detoxification services, and various outpatient options employing evidence-based techniques like cognitive behavioral therapy and anger management. They also offer specialized programs for individuals who have faced trauma, intimate partner violence, or have had interactions with the criminal justice system. By implementing a gender-specific approach for both men and women, this facility is committed to providing personalized care and support that addresses the individual needs of each client. Discover compassionate and effective rehabilitation at CBI Encompass Health Services.

CBI Encompass Health Services

CBI Encompass Health Services located in Colorado City, AZ, provides a wide array of treatment options for individuals battling substance use issues and co-existing mental health disorders. The center specializes in intensive outpatient care, along with various outpatient programs and detoxification services, aimed at adults and the senior population. By implementing evidence-based modalities such as cognitive behavioral therapy and anger management techniques, the facility serves both male and female participants. There are dedicated programs for those who have faced trauma, domestic violence, or are involved with the judicial system. CBI Encompass Health Services prioritizes delivering high-quality support for individuals pursuing recovery from addiction and mental health struggles.

CBI Encompass Health Services

CBI Encompass Health Services, situated in Fredonia, AZ, delivers thorough addiction recovery for adults and older adults. They specialize in intensive outpatient, outpatient detox, and general outpatient programs. Their approach emphasizes cognitive behavioral therapy, anger management, and short-term interventions, effectively addressing dual diagnoses of substance use and severe mental health conditions. CBI Encompass Health Services also offers distinct support for individuals with trauma histories, domestic violence experiences, and legal entanglements. Serving both men and women, the center provides personalized care. Discover effective treatment and compassionate assistance at CBI Encompass Health Services.

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Catholic Charities Maine in Auburn, ME, provides comprehensive long-term residential care for adult men facing substance use disorders and co-occurring severe mental health conditions. This center delivers round-the-clock support through proven methods such as 12-step facilitation and anger management. It features distinct programs tailored for active military members, survivors of domestic abuse, and individuals needing short-term interventions. Serving adult, senior, and young adult males, the facility prioritizes personalized treatment plans and assistance for each client's recovery path. Catholic Charities Maine is committed to delivering excellent rehabilitation services in a secure and supportive setting.

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Situated in Cortland, NY, Catholic Charities of Cortland County delivers extensive services for substance use rehabilitation and transitional housing. This center features long-term residential programs that emphasize 12-step principles, anger management techniques, and short intervention strategies. With a strong focus on individualized support, it serves both adult and young adult clients of any gender. Those in need of a sober living environment, halfway house, or around-the-clock residential care can anticipate high-quality, tailored assistance. Catholic Charities of Cortland County is recognized for its dedication to personalized treatment approaches and comprehensive recovery solutions for individuals on their journey to sobriety.

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Situated in Utica, NY, Catholic Charities/Diocese of Syracuse provides high-quality substance abuse treatment in a long-term residential framework for adult males. This center delivers targeted care for individuals dealing with both mental health and substance abuse challenges, utilizing methods such as anger management, cognitive-behavioral therapy, and motivational techniques. Programs are customized for clients with a history of trauma. The center also features transitional housing and sober living options. Aimed at adult, senior, and younger adult males, this facility creates a nurturing atmosphere for individuals pursuing extensive rehabilitation support.

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Catholic Social Services of the UP in Escanaba, MI, delivers extensive addiction recovery services to adults and young adults. Their offerings include outpatient treatment with methadone, buprenorphine, or naltrexone, alongside general outpatient care. They also utilize therapeutic interventions such as 12-step facilitation, brief intervention, and cognitive behavioral therapy. The center features specialized programs designed for active military personnel, adult men, and adult women, guaranteeing personalized support for varied requirements. This facility, catering to both male and female individuals, is dedicated to providing excellent care and encouragement for those pursuing freedom from addiction. Catholic Social Services of the UP is distinguished by its focused approaches and unwavering dedication to assisting individuals in attaining sustained recovery.

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Cayuga Addiction Recovery Services, located in Trumansburg, NY, provides extensive live-in treatment for adult males struggling with addiction and concurrent severe mental health issues. This establishment is particularly skilled in creating individualized plans for individuals with histories of intimate partner violence, domestic abuse, and sexual assault. Employing 12-step encouragement, emotional regulation strategies, and concise intervention methods, the center delivers holistic support to adults, older individuals, and younger adults. The round-the-clock residential atmosphere offers a nurturing space for men pursuing sobriety. Cayuga Addiction Recovery Services is dedicated to offering excellent services with a unique emphasis on tackling trauma and co-occurring conditions with empathy and efficacy.

Frequently Asked Questions

What is buprenorphine and how does it treat opioid addiction?
Buprenorphine is a partial opioid agonist medication approved by the FDA for treating opioid use disorder. It binds to the same receptors as heroin and fentanyl but produces a much weaker effect, reducing cravings and withdrawal symptoms without causing intense euphoria. Buprenorphine has a ceiling effect, meaning its opioid effects plateau at moderate doses, making it safer than methadone in terms of overdose risk.
What is the difference between Suboxone and Subutex?
Suboxone contains two active ingredients — buprenorphine and naloxone — while Subutex contains only buprenorphine without naloxone. The naloxone in Suboxone is included as an abuse deterrent; it remains inactive when taken sublingually as prescribed but triggers withdrawal if the medication is injected. Subutex is generally reserved for patients who cannot tolerate naloxone, such as pregnant women.
What is a Sublocade injection and how does it work?
Sublocade is a once-monthly injectable form of buprenorphine administered as a subcutaneous injection in the abdominal area. After injection, the medication forms a solid deposit under the skin that slowly releases buprenorphine over the course of a month. This eliminates daily dosing and removes the possibility of missed doses or medication diversion.
What are the common side effects of Suboxone?
Common Suboxone side effects include headache, nausea, constipation, insomnia, sweating, and mouth numbness or pain from sublingual administration. Some patients also experience dizziness, drowsiness, and blurred vision, particularly when starting treatment. Most side effects diminish within the first few weeks as the body adjusts. Patients should report difficulty breathing or signs of allergic reaction immediately.
What happens during Suboxone withdrawal?
Suboxone withdrawal occurs when a patient stops taking the medication abruptly after prolonged use, with symptoms including muscle aches, anxiety, insomnia, nausea, and irritability. A medically supervised taper is strongly recommended, typically reducing the dose by small increments over weeks or months. The risk of opioid relapse is significantly higher during unsupervised discontinuation.
How does Suboxone compare to methadone?
Suboxone and methadone are both effective for opioid use disorder but differ in key ways. Methadone is a full opioid agonist dispensed daily at licensed clinics, while Suboxone is a partial agonist that can be prescribed by qualified physicians and taken at home. Suboxone carries a lower overdose risk due to its ceiling effect and offers greater convenience, though methadone may be more appropriate for patients with severe, long-standing dependence.
How can I find a Suboxone clinic or doctor near me?
The most reliable way to find a Suboxone provider is through SAMHSA's online treatment locator at findtreatment.gov, which allows you to search by location and filter for buprenorphine providers. Many primary care offices, addiction treatment centers, and telehealth platforms now offer Suboxone prescriptions following the elimination of the federal X-waiver requirement in early 2023.
What is Zubsolv and how is it different from Suboxone?
Zubsolv is a brand-name buprenorphine and naloxone sublingual tablet that features a mint flavor and dissolves faster under the tongue than other options. Due to its higher bioavailability, Zubsolv uses different dosing strengths — a Zubsolv 5.7 mg/1.4 mg tablet is considered equivalent to a Suboxone 8 mg/2 mg dose. Patients switching between products should work closely with their prescriber for correct dose conversion.
Does Medicaid cover Suboxone treatment?
Yes — Medicaid covers buprenorphine (including Suboxone, Sublocade, Subutex, Zubsolv, and Brixadi) for opioid use disorder in all 50 states, as required by the SUPPORT Act of 2018. Medicaid is the largest single payer for MAT in the US. Coverage details vary by state — some require prior authorization or limit certain formulations. Many OBOT clinics accept Medicaid directly; telehealth Suboxone providers also bill Medicaid in most states. Bring your Medicaid card to your intake appointment.
Can I get Suboxone through telehealth?
Yes. After the MAT Act of 2023 permanently eliminated the X-waiver requirement, any licensed prescriber can prescribe Suboxone via telehealth in most states. The DEA also extended COVID-era telehealth flexibilities through at least 2025, allowing virtual Suboxone induction without a prior in-person visit. Several specialty platforms — Bicycle Health, Ophelia, Workit Health, Boulder Care — offer Medicaid-accepting telehealth Suboxone treatment. Telehealth has dramatically expanded access in rural and underserved areas with no nearby OBOT physicians.

About Buprenorphine (Suboxone)

Buprenorphine is classified as a partial opioid agonist, meaning it activates opioid receptors in the brain but to a much lesser degree than full agonists such as heroin, fentanyl, or oxycodone. This partial activation suppresses withdrawal symptoms and reduces cravings without producing dangerous respiratory depression or intense euphoria. Buprenorphine also has an unusually high binding affinity for the mu-opioid receptor, effectively blocking other opioids from attaching — providing a protective effect against relapse-related overdose.

How Buprenorphine Works

One of the defining features of buprenorphine is its ceiling effect — after a certain dose threshold, increasing the amount does not produce additional opioid effects. This dramatically reduces the risk of fatal overdose compared to methadone or illicit opioids. The ceiling effect, combined with its long duration of action (24 to 72 hours), makes buprenorphine one of the safest and most effective tools in medication-assisted treatment (MAT). Approved by the FDA in 2002, buprenorphine was a breakthrough because it could be prescribed in outpatient settings rather than requiring daily clinic visits.

Buprenorphine Brand Comparison: Suboxone, Subutex, Sublocade, Zubsolv, Brixadi

Buprenorphine is available under several FDA-approved brand names, each with distinct formulations, dosing schedules, and clinical use cases. The comparison below highlights the key differences:

BrandActive ingredientFormFrequencySettingFDA yearBest for
SuboxoneBuprenorphine + naloxoneSublingual film / tabletDailyOBOT, telehealth, retail pharmacy2002Most prescribed; naloxone deters injection misuse
SubutexBuprenorphine (alone)Sublingual tabletDailyOBOT2002Pregnancy; documented naloxone sensitivity
SublocadeBuprenorphine extended-releaseSubcutaneous injection (ATRIGEL depot)MonthlyClinic-administered2017No daily dosing; eliminates diversion risk
ZubsolvBuprenorphine + naloxoneSublingual tablet (higher bioavailability)DailyOBOT2013Faster dissolution; mint flavor; lower mg/dose
BrixadiBuprenorphine extended-releaseSubcutaneous injectionWeekly or monthlyClinic2023Newer alternative to Sublocade; weekly option for induction

All five medications are Schedule III controlled substances and equivalent in clinical efficacy at appropriate doses. The choice depends on adherence patterns, lifestyle, insurance coverage, and clinical context (e.g., pregnancy, prior injection use, daily-dosing burden). Many patients begin on sublingual Suboxone for stabilization and transition to monthly Sublocade or weekly Brixadi after sustained recovery.

Buprenorphine Side Effects

Common buprenorphine side effects include:

  • Headache and dizziness
  • Nausea and vomiting, especially during induction
  • Constipation and insomnia
  • Excessive sweating
  • Mouth numbness or oral discomfort from sublingual formulations

More serious side effects may include respiratory depression (particularly when combined with benzodiazepines or alcohol), liver problems, and allergic reactions. For most patients, side effects are mild and resolve within one to two weeks. The benefits in preventing relapse and overdose death significantly outweigh the risks.

Buprenorphine Dosage and Induction

Treatment begins with an induction phase where the patient must be in mild to moderate opioid withdrawal. Common induction doses range from 2 mg to 8 mg on the first day, with increases over the following days. Most patients stabilize on 8 mg to 24 mg per day, with 16 mg being the most commonly prescribed dose. Research suggests doses of 16 mg or higher are associated with better retention and outcomes. Dosage should always be adjusted under medical supervision.

Buprenorphine/Naloxone Combination

Many buprenorphine formulations include naloxone as an abuse deterrent. When taken sublingually as directed, naloxone has very low bioavailability and produces no clinical effect. However, if someone attempts to inject the medication, the naloxone component becomes fully active and triggers severe withdrawal. This design discourages injection misuse while having no impact on patients who take the medication correctly. The combination is the standard first-line formulation for opioid addiction treatment.

Suboxone: Sublingual Buprenorphine

Suboxone is the most recognized brand name for buprenorphine-naloxone and is most commonly dispensed as a sublingual film (Suboxone strips) that dissolves under the tongue. Suboxone has transformed opioid treatment by enabling millions of patients to receive effective pharmacotherapy in outpatient settings without the daily clinic visits required by methadone programs.

Suboxone Side Effects

Commonly reported Suboxone side effects include headache, nausea, tongue or mouth irritation, constipation, insomnia, sweating, and decreased libido. The sublingual film can cause irritation or small sores inside the mouth — rotating placement between under the tongue and against the cheek helps minimize this. Patients should not eat, drink, or smoke while the film is dissolving.

Suboxone Strips: Film vs. Tablet

Suboxone strips (sublingual film) have largely replaced the original tablet form. The film dissolves more quickly (two to four minutes), provides more consistent absorption, and is harder to divert due to individual foil packaging. Generic buprenorphine-naloxone tablets are often less expensive and may be preferred for cost reasons. Both are therapeutically equivalent when taken as prescribed.

Suboxone Treatment Programs

Comprehensive Suboxone treatment typically includes three phases:

  • Induction: Initial dosing under medical supervision, requiring the patient to be in early withdrawal
  • Stabilization: Dose adjustment until cravings and withdrawal are minimal, usually one to two months
  • Maintenance: Stable dosing for an extended period — often a year or longer — combined with counseling and behavioral therapy

Evidence consistently shows that longer treatment durations are associated with better outcomes. Most addiction medicine experts recommend a minimum of one to two years of maintenance therapy.

Find a Suboxone Clinic Near You — OBOT & Telehealth Options

Finding a Suboxone clinic has become significantly easier since the federal government eliminated the X-waiver requirement in January 2023, meaning any provider with a standard DEA license can now prescribe Suboxone. Patients can search SAMHSA's treatment locator at findtreatment.gov or use our directory to locate nearby facilities that offer buprenorphine-based treatment.

Suboxone Doctors Near Me

Beyond SAMHSA's locator, many state health departments maintain directories of addiction treatment providers. Telehealth has dramatically expanded access — several platforms now offer virtual Suboxone consultations, which is especially valuable for patients in rural areas. When selecting a provider, look for those offering comprehensive treatment including counseling, not just medication prescriptions.

Suboxone Withdrawal and Tapering

Suboxone withdrawal can include muscle aches, anxiety, insomnia, nausea, sweating, and intense opioid cravings. A gradual, medically supervised taper is recommended — typically reducing the dose by 10 to 25 percent every one to four weeks. Slower tapers over several months produce fewer symptoms and lower relapse rates. There is no medically mandated time limit for Suboxone treatment, and many patients benefit from indefinite maintenance.

Suboxone vs Methadone

Suboxone can be prescribed in office settings and taken at home, carries lower overdose risk due to its ceiling effect, and offers greater scheduling flexibility. Methadone is a full agonist that may be more effective for severe, long-standing dependence but must be dispensed at licensed clinics with daily visits. Neither is inherently superior — the best choice keeps the patient in treatment. Some patients may also benefit from naltrexone, a non-opioid alternative.

Sublocade: Monthly Buprenorphine Injection

Sublocade delivers buprenorphine as a once-monthly subcutaneous injection in the abdominal area using the ATRIGEL delivery system, which forms a solid biodegradable depot that slowly releases medication. Patients must first stabilize on sublingual buprenorphine (8 mg+ daily) for at least seven days. Treatment typically begins with two 300 mg injections, followed by maintenance on 300 mg or 100 mg. Sublocade eliminates concerns about daily adherence, missed doses, and medication diversion.

Sublocade Side Effects

The most common Sublocade side effects are injection-site reactions (pain, itching, redness, or a noticeable lump), nausea, constipation, headache, and fatigue. The injection-site lump is normal and gradually diminishes as medication is absorbed. Patients should avoid rubbing or massaging the site. Elevated liver enzymes may also occur but are usually mild and transient.

Subutex: Buprenorphine Without Naloxone

Subutex was the original brand-name buprenorphine product. While the brand has been discontinued, generic buprenorphine-only tablets remain available. Buprenorphine monotherapy is typically reserved for pregnant patients (to avoid naloxone exposure to the fetus), patients with documented naloxone sensitivity, or sometimes during the induction phase before transitioning to the combination product.

Subutex vs Suboxone

The primary difference is the absence of naloxone in Subutex. Because Subutex lacks the abuse-deterrent naloxone component, it may carry slightly higher diversion risk, and many insurance formularies prioritize the combination as the default. Current clinical guidelines favor buprenorphine-only formulations primarily for pregnancy and naloxone sensitivity.

Zubsolv: Alternative Buprenorphine Brand

Zubsolv is a buprenorphine-naloxone sublingual tablet featuring a mint flavor and faster dissolution (under two minutes). Due to enhanced bioavailability, Zubsolv uses different dose strengths — a 5.7 mg/1.4 mg tablet equals a Suboxone 8 mg/2 mg dose. Zubsolv is available in multiple strengths for flexible dosing during both induction and maintenance.

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Medically Reviewed Updated July 2026

Reviewed by licensed addiction specialists. Information reflects current clinical guidance.

Sources:SAMHSA·NIDA·CDC

Need immediate help? Call SAMHSA: 1-800-662-4357 (24/7, free)