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Medically Reviewed Content
Updated: September 2026
Sources: SAMHSA, NIDA

Suboxone Clinic Near You: Buprenorphine Treatment for Opioid Addiction

Find a Suboxone clinic near you. Buprenorphine — sold under brand names Suboxone, Sublocade, Subutex, Zubsolv, and Brixadi — is the most-prescribed MAT for opioid use disorder. It is a partial mu-opioid agonist with a ceiling effect that dramatically reduces overdose risk vs. methadone. After the MAT Act of 2023 eliminated the X-waiver requirement, any licensed prescriber can prescribe buprenorphine in office-based settings (OBOT), via telehealth, or at retail pharmacies. Buprenorphine is a Schedule III controlled substance and is covered by Medicaid in all 50 states.

Found 7,094 treatment centers offering buprenorphine (suboxone) across the United States.

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Catholic Charities/Rockville Centre

Situated in Hampton Bays, NY, Catholic Charities/Rockville Centre specializes in comprehensive treatment for adults and young adults dealing with substance use issues, particularly those with co-occurring serious mental health conditions or emotional challenges. The center offers outpatient services, including treatments with methadone, buprenorphine, or naltrexone, along with standard outpatient care. Emphasizing techniques such as 12-step facilitation, brief interventions, and cognitive behavioral therapy, this facility serves active duty military members as well as adult men and women. Catholic Charities/Rockville Centre provides customized programs for both genders, ensuring high-quality support for individuals on their path to recovery.

Catholic Community Services

Catholic Community Services located in Seattle, WA provides outpatient treatment for substance use disorders in adults, including those who may also experience significant mental health challenges or emotional issues. This center offers a variety of treatment options, such as outpatient care utilizing methadone, buprenorphine, or naltrexone, alongside standard outpatient services. Emphasizing personalized care, the facility employs evidence-based methods like cognitive behavioral therapy, motivational interviewing, and brief interventions. Customized programs are available for both adults and young adults, accommodating the needs of all genders. For individuals in search of effective addiction treatment that prioritizes individualized support, this center could be an excellent choice.

Cazenovia Manor
Buffalo, NY

Cazenovia Manor, located in Buffalo, NY, is a premier rehabilitation facility dedicated to providing long-term residential treatment for adult men dealing with substance use issues. The center delivers extensive support for individuals who also face mental health challenges concurrently. By implementing proven strategies such as anger management, cognitive behavioral therapy, and motivational incentives, the program serves diverse age groups, including adults, seniors, and young adults in pursuit of recovery. Cazenovia Manor is distinguished by its commitment to addressing both substance use problems and significant mental health disorders, fostering an environment conducive to comprehensive healing. Renowned for its exemplary care and tailored programs, this center serves as a guiding light for those embarking on their path to sobriety.

Cedar Mountain Center at

Situated in Cody, WY, Cedar Mountain Center offers an extensive range of addiction recovery services for both adults and young adults. With a focus on detoxification, treatment for substance use disorders, and addressing co-occurring mental health issues, the center provides round-the-clock hospital inpatient care. Utilizing evidence-driven methods such as cognitive behavioral therapy and 12-step support, clients benefit from care that is customized to meet their specific needs. The center also features specialized programs designed for individuals facing dual diagnoses. Committed to delivering high-quality and tailored treatment, Cedar Mountain Center fosters a nurturing atmosphere for all clients pursuing recovery from addiction and co-occurring conditions.

Cedar Recovery
Knoxville, TN

Cedar Recovery, situated in Knoxville, TN, is a prominent rehabilitation facility dedicated to helping adults and young adults overcome substance use issues. The center offers a range of services, including outpatient care, as well as methadone, buprenorphine, or naltrexone options. Cedar Recovery employs a holistic strategy to treatment, integrating anger management, brief intervention strategies, and cognitive behavioral therapy to meet the unique needs of each client. This center is proud of its tailored services for both men and women. With a strong emphasis on customized care and high standards of support, Cedar Recovery is an excellent option for individuals in search of effective addiction recovery solutions.

Cedar Recovery
Shelbyville, TN

Cedar Recovery, located in Shelbyville, TN, is a prominent rehabilitation center focused on helping adults and young adults with substance use issues. The facility provides a variety of care options, including intensive outpatient programs, outpatient services, and treatments involving methadone, buprenorphine, or naltrexone. Cedar Recovery emphasizes a comprehensive strategy for recovery, featuring counseling for substance use disorders and trauma, as well as telehealth services. Its dedication to personalized treatment distinguishes this center as it serves both male and female clients. If you're looking for expert addiction care, Cedar Recovery is committed to guiding you on your path to a healthier life.

Cedar Recovery
Knoxville, TN

Cedar Recovery, situated in Knoxville, TN, delivers extensive treatment options for substance use issues targeting both adults and young adults. This center specializes in outpatient therapies, including methadone/buprenorphine and naltrexone treatments, alongside standard outpatient services. The facility employs customized strategies such as 12-step programs, anger management, and brief interventions. Cedar Recovery emphasizes personalized support, accommodating clients of all genders. Their dedication to high-quality care and custom treatment plans establishes them as an essential resource for individuals looking to overcome addiction in a nurturing setting.

Celadon Recovery Center

Situated in Fort Myers, Florida, Celadon Recovery Center delivers extensive addiction treatment services for both adults and young adults. The center features long-term residential options, detox programs, and around-the-clock residential support. Its expertise lies in addressing substance use disorders, co-occurring mental health challenges, and emotional difficulties. By emphasizing 12-step approaches, anger management, and brief interventions, Celadon Recovery Center customizes its services to cater to the distinct needs of every individual. Specialized programs are offered for male and female adults, as well as clients who have faced intimate partner or domestic abuse. With a strong dedication to high-quality care, this center fosters a nurturing atmosphere conducive to healing and recovery.

Celadon Recovery Outpatient Services

Celadon Recovery Outpatient Services, located in Fort Myers, FL, delivers a wide range of addiction treatment options, encompassing detox and therapies for substance use disorders. The facility specializes in intensive outpatient treatment, outpatient programs, and detox services. Emphasizing 12-step principles, anger management techniques, and brief intervention methods, it serves adult men and women, including those affected by intimate partner or domestic violence. Catering to both adults and young adults of all genders, Celadon Recovery Outpatient Services is dedicated to providing personalized care, making it a top option for individuals in need of focused and effective rehabilitation approaches.

Cedar Recovery
Mount Juliet, TN

Cedar Recovery, situated in Mount Juliet, TN, delivers a broad spectrum of outpatient services aimed at treating addiction. The center specializes in detox and substance use therapies, providing options like outpatient methadone/buprenorphine or naltrexone treatments alongside ongoing outpatient programs. By employing techniques such as motivational interviewing, relapse prevention methods, and counseling for substance use disorders, Cedar Recovery serves adult men and women, including those in active military service. With an emphasis on adults and young adults, this facility provides customized care for male and female individuals alike. Discover personalized care and dedicated support at Cedar Recovery.

Cen Clear Child Services Inc

Situated in Philipsburg, PA, Cen Clear Child Services Inc offers an all-encompassing approach to substance abuse treatment for adults dealing with serious mental health issues and for children facing significant emotional challenges. The center provides various treatment options, including intensive outpatient programs, outpatient services, and medication-assisted therapies using methadone, buprenorphine, or naltrexone. Their methodologies incorporate anger management, cognitive behavioral therapy, and the Matrix Model. Programs are customized for adult men and women, with particular attention to the needs of both younger and older adults. Committed to delivering high-quality care rooted in evidence-based practices, this center remains focused on aiding individuals in their recovery journey.

Catholic Charities of Miami

Catholic Charities of Miami, situated in Miami, FL, provides extensive addiction recovery services for adults and adolescents. This center excels in addressing dual diagnoses, treating individuals with both substance abuse and severe mental health conditions, alongside children experiencing significant emotional challenges. Offering extended residential stays, daily outpatient services, and medication-assisted treatment including methadone, buprenorphine, or naltrexone, the facility tailors each recovery journey with methods like 12-step encouragement, emotional regulation training, and short-term counseling. Special therapeutic offerings are available for those with trauma histories and co-occurring conditions. Emphasizing superior support, Catholic Charities of Miami serves both men and women in pursuit of successful recovery.

Cen Clear Child Services Inc

Cen Clear Child Services Inc, situated in Clarion, PA, provides dedicated substance use recovery programs for adults and older adults. Their services encompass intensive outpatient, outpatient, and medication-assisted treatment options using methadone, buprenorphine, or naltrexone. The center employs evidence-based therapies such as anger management, cognitive behavioral therapy, and the Matrix Model. They offer distinct programs designed for adult men and women, facilitating personalized care. Cen Clear Child Services Inc is committed to delivering high-quality rehabilitation to all clients, adapting services to individual requirements. For those in need of thorough addiction support and a nurturing atmosphere, Cen Clear Child Services Inc strives to guide individuals toward sustained sobriety.

Catholic Charities of Utica/Rome

Catholic Charities of Utica/Rome, situated in Utica, NY, provides extended residential care for adult women battling substance use disorders within a nurturing atmosphere. This establishment offers interim lodging, structured recovery housing, and sober living arrangements for individuals managing both mental health and substance dependency issues. The program employs proven therapeutic methods, including techniques for managing anger, cognitive restructuring, and motivational strategies, to adeptly meet each person's unique challenges. Emphasizing support for those with a history of trauma, the center serves adults, older adults, and younger adults in search of all-encompassing support within a women-only environment. Catholic Charities of Utica/Rome is committed to delivering superior rehabilitative services to foster enduring recovery.

Cecil Community Recovery Center LLC

Cecil Community Recovery Center LLC in Elkton, MD provides outpatient addiction treatment for adults and young adults. Their services include specialized programs for methadone, buprenorphine, or naltrexone treatment, as well as general outpatient care. They employ therapeutic methods such as 12-step facilitation, brief intervention, and cognitive behavioral therapy. This center offers gender-specific treatment and is dedicated to providing high-quality, personalized support for individuals pursuing recovery from substance use disorders.

Cen Clear Child Services Inc

Situated in Huntingdon, PA, Cen Clear Child Services Inc provides extensive treatment options for substance abuse while addressing co-occurring disorders. The facility offers a range of services, including intensive outpatient programs, outpatient care, and treatments with methadone, buprenorphine, or naltrexone. Utilizing proven strategies such as cognitive behavioral therapy, anger management, and the Matrix Model, the center serves both adult men and women, as well as senior clients. With an emphasis on specialized care for both adults and children, gender-specific programs, and a strong dedication to high-quality treatment, individuals in search of effective rehabilitation can find the necessary support and recovery opportunities at this center.

Cen Clear Child Services Inc

Cen Clear Child Services Inc, situated in Clearfield, PA, delivers excellent rehabilitative care for those facing addiction and intertwined mental health challenges. The center offers various treatment levels, including intensive outpatient, outpatient, and standard outpatient programs. These services incorporate proven therapeutic methods like anger management, cognitive behavioral therapy, and the Matrix Model. Catering to adult men and women, this establishment serves adults and older adults irrespective of gender. Cen Clear Child Services Inc emphasizes personalized support and a collaborative treatment strategy to provide superior recovery assistance.

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Situated in Utica, NY, Catholic Charities/Diocese of Syracuse provides high-quality substance abuse treatment in a long-term residential framework for adult males. This center delivers targeted care for individuals dealing with both mental health and substance abuse challenges, utilizing methods such as anger management, cognitive-behavioral therapy, and motivational techniques. Programs are customized for clients with a history of trauma. The center also features transitional housing and sober living options. Aimed at adult, senior, and younger adult males, this facility creates a nurturing atmosphere for individuals pursuing extensive rehabilitation support.

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Catholic Social Services of the UP in Escanaba, MI, delivers extensive addiction recovery services to adults and young adults. Their offerings include outpatient treatment with methadone, buprenorphine, or naltrexone, alongside general outpatient care. They also utilize therapeutic interventions such as 12-step facilitation, brief intervention, and cognitive behavioral therapy. The center features specialized programs designed for active military personnel, adult men, and adult women, guaranteeing personalized support for varied requirements. This facility, catering to both male and female individuals, is dedicated to providing excellent care and encouragement for those pursuing freedom from addiction. Catholic Social Services of the UP is distinguished by its focused approaches and unwavering dedication to assisting individuals in attaining sustained recovery.

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Cayuga Addiction Recovery Services, located in Trumansburg, NY, provides extensive live-in treatment for adult males struggling with addiction and concurrent severe mental health issues. This establishment is particularly skilled in creating individualized plans for individuals with histories of intimate partner violence, domestic abuse, and sexual assault. Employing 12-step encouragement, emotional regulation strategies, and concise intervention methods, the center delivers holistic support to adults, older individuals, and younger adults. The round-the-clock residential atmosphere offers a nurturing space for men pursuing sobriety. Cayuga Addiction Recovery Services is dedicated to offering excellent services with a unique emphasis on tackling trauma and co-occurring conditions with empathy and efficacy.

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Cen Clear Child Services Inc, situated in Coalport, PA, provides an extensive selection of substance use treatment options for both adults and seniors. The center focuses on addressing co-occurring substance use issues along with significant mental health challenges and emotional problems in children. It offers various treatment formats, including intensive outpatient, outpatient, and standard outpatient programs, ensuring personalized care through evidence-based methods like cognitive behavioral therapy, anger management, and the Matrix Model. Special programs designed specifically for men and women deliver effective, gender-focused support. Cen Clear Child Services Inc is dedicated to offering top-notch care that aids individuals in their journey towards enduring recovery.

Frequently Asked Questions

What is buprenorphine and how does it treat opioid addiction?
Buprenorphine is a partial opioid agonist medication approved by the FDA for treating opioid use disorder. It binds to the same receptors as heroin and fentanyl but produces a much weaker effect, reducing cravings and withdrawal symptoms without causing intense euphoria. Buprenorphine has a ceiling effect, meaning its opioid effects plateau at moderate doses, making it safer than methadone in terms of overdose risk.
What is the difference between Suboxone and Subutex?
Suboxone contains two active ingredients — buprenorphine and naloxone — while Subutex contains only buprenorphine without naloxone. The naloxone in Suboxone is included as an abuse deterrent; it remains inactive when taken sublingually as prescribed but triggers withdrawal if the medication is injected. Subutex is generally reserved for patients who cannot tolerate naloxone, such as pregnant women.
What is a Sublocade injection and how does it work?
Sublocade is a once-monthly injectable form of buprenorphine administered as a subcutaneous injection in the abdominal area. After injection, the medication forms a solid deposit under the skin that slowly releases buprenorphine over the course of a month. This eliminates daily dosing and removes the possibility of missed doses or medication diversion.
What are the common side effects of Suboxone?
Common Suboxone side effects include headache, nausea, constipation, insomnia, sweating, and mouth numbness or pain from sublingual administration. Some patients also experience dizziness, drowsiness, and blurred vision, particularly when starting treatment. Most side effects diminish within the first few weeks as the body adjusts. Patients should report difficulty breathing or signs of allergic reaction immediately.
What happens during Suboxone withdrawal?
Suboxone withdrawal occurs when a patient stops taking the medication abruptly after prolonged use, with symptoms including muscle aches, anxiety, insomnia, nausea, and irritability. A medically supervised taper is strongly recommended, typically reducing the dose by small increments over weeks or months. The risk of opioid relapse is significantly higher during unsupervised discontinuation.
How does Suboxone compare to methadone?
Suboxone and methadone are both effective for opioid use disorder but differ in key ways. Methadone is a full opioid agonist dispensed daily at licensed clinics, while Suboxone is a partial agonist that can be prescribed by qualified physicians and taken at home. Suboxone carries a lower overdose risk due to its ceiling effect and offers greater convenience, though methadone may be more appropriate for patients with severe, long-standing dependence.
How can I find a Suboxone clinic or doctor near me?
The most reliable way to find a Suboxone provider is through SAMHSA's online treatment locator at findtreatment.gov, which allows you to search by location and filter for buprenorphine providers. Many primary care offices, addiction treatment centers, and telehealth platforms now offer Suboxone prescriptions following the elimination of the federal X-waiver requirement in early 2023.
What is Zubsolv and how is it different from Suboxone?
Zubsolv is a brand-name buprenorphine and naloxone sublingual tablet that features a mint flavor and dissolves faster under the tongue than other options. Due to its higher bioavailability, Zubsolv uses different dosing strengths — a Zubsolv 5.7 mg/1.4 mg tablet is considered equivalent to a Suboxone 8 mg/2 mg dose. Patients switching between products should work closely with their prescriber for correct dose conversion.
Does Medicaid cover Suboxone treatment?
Yes — Medicaid covers buprenorphine (including Suboxone, Sublocade, Subutex, Zubsolv, and Brixadi) for opioid use disorder in all 50 states, as required by the SUPPORT Act of 2018. Medicaid is the largest single payer for MAT in the US. Coverage details vary by state — some require prior authorization or limit certain formulations. Many OBOT clinics accept Medicaid directly; telehealth Suboxone providers also bill Medicaid in most states. Bring your Medicaid card to your intake appointment.
Can I get Suboxone through telehealth?
Yes. After the MAT Act of 2023 permanently eliminated the X-waiver requirement, any licensed prescriber can prescribe Suboxone via telehealth in most states. The DEA also extended COVID-era telehealth flexibilities through at least 2025, allowing virtual Suboxone induction without a prior in-person visit. Several specialty platforms — Bicycle Health, Ophelia, Workit Health, Boulder Care — offer Medicaid-accepting telehealth Suboxone treatment. Telehealth has dramatically expanded access in rural and underserved areas with no nearby OBOT physicians.

About Buprenorphine (Suboxone)

Buprenorphine is classified as a partial opioid agonist, meaning it activates opioid receptors in the brain but to a much lesser degree than full agonists such as heroin, fentanyl, or oxycodone. This partial activation suppresses withdrawal symptoms and reduces cravings without producing dangerous respiratory depression or intense euphoria. Buprenorphine also has an unusually high binding affinity for the mu-opioid receptor, effectively blocking other opioids from attaching — providing a protective effect against relapse-related overdose.

How Buprenorphine Works

One of the defining features of buprenorphine is its ceiling effect — after a certain dose threshold, increasing the amount does not produce additional opioid effects. This dramatically reduces the risk of fatal overdose compared to methadone or illicit opioids. The ceiling effect, combined with its long duration of action (24 to 72 hours), makes buprenorphine one of the safest and most effective tools in medication-assisted treatment (MAT). Approved by the FDA in 2002, buprenorphine was a breakthrough because it could be prescribed in outpatient settings rather than requiring daily clinic visits.

Buprenorphine Brand Comparison: Suboxone, Subutex, Sublocade, Zubsolv, Brixadi

Buprenorphine is available under several FDA-approved brand names, each with distinct formulations, dosing schedules, and clinical use cases. The comparison below highlights the key differences:

BrandActive ingredientFormFrequencySettingFDA yearBest for
SuboxoneBuprenorphine + naloxoneSublingual film / tabletDailyOBOT, telehealth, retail pharmacy2002Most prescribed; naloxone deters injection misuse
SubutexBuprenorphine (alone)Sublingual tabletDailyOBOT2002Pregnancy; documented naloxone sensitivity
SublocadeBuprenorphine extended-releaseSubcutaneous injection (ATRIGEL depot)MonthlyClinic-administered2017No daily dosing; eliminates diversion risk
ZubsolvBuprenorphine + naloxoneSublingual tablet (higher bioavailability)DailyOBOT2013Faster dissolution; mint flavor; lower mg/dose
BrixadiBuprenorphine extended-releaseSubcutaneous injectionWeekly or monthlyClinic2023Newer alternative to Sublocade; weekly option for induction

All five medications are Schedule III controlled substances and equivalent in clinical efficacy at appropriate doses. The choice depends on adherence patterns, lifestyle, insurance coverage, and clinical context (e.g., pregnancy, prior injection use, daily-dosing burden). Many patients begin on sublingual Suboxone for stabilization and transition to monthly Sublocade or weekly Brixadi after sustained recovery.

Buprenorphine Side Effects

Common buprenorphine side effects include:

  • Headache and dizziness
  • Nausea and vomiting, especially during induction
  • Constipation and insomnia
  • Excessive sweating
  • Mouth numbness or oral discomfort from sublingual formulations

More serious side effects may include respiratory depression (particularly when combined with benzodiazepines or alcohol), liver problems, and allergic reactions. For most patients, side effects are mild and resolve within one to two weeks. The benefits in preventing relapse and overdose death significantly outweigh the risks.

Buprenorphine Dosage and Induction

Treatment begins with an induction phase where the patient must be in mild to moderate opioid withdrawal. Common induction doses range from 2 mg to 8 mg on the first day, with increases over the following days. Most patients stabilize on 8 mg to 24 mg per day, with 16 mg being the most commonly prescribed dose. Research suggests doses of 16 mg or higher are associated with better retention and outcomes. Dosage should always be adjusted under medical supervision.

Buprenorphine/Naloxone Combination

Many buprenorphine formulations include naloxone as an abuse deterrent. When taken sublingually as directed, naloxone has very low bioavailability and produces no clinical effect. However, if someone attempts to inject the medication, the naloxone component becomes fully active and triggers severe withdrawal. This design discourages injection misuse while having no impact on patients who take the medication correctly. The combination is the standard first-line formulation for opioid addiction treatment.

Suboxone: Sublingual Buprenorphine

Suboxone is the most recognized brand name for buprenorphine-naloxone and is most commonly dispensed as a sublingual film (Suboxone strips) that dissolves under the tongue. Suboxone has transformed opioid treatment by enabling millions of patients to receive effective pharmacotherapy in outpatient settings without the daily clinic visits required by methadone programs.

Suboxone Side Effects

Commonly reported Suboxone side effects include headache, nausea, tongue or mouth irritation, constipation, insomnia, sweating, and decreased libido. The sublingual film can cause irritation or small sores inside the mouth — rotating placement between under the tongue and against the cheek helps minimize this. Patients should not eat, drink, or smoke while the film is dissolving.

Suboxone Strips: Film vs. Tablet

Suboxone strips (sublingual film) have largely replaced the original tablet form. The film dissolves more quickly (two to four minutes), provides more consistent absorption, and is harder to divert due to individual foil packaging. Generic buprenorphine-naloxone tablets are often less expensive and may be preferred for cost reasons. Both are therapeutically equivalent when taken as prescribed.

Suboxone Treatment Programs

Comprehensive Suboxone treatment typically includes three phases:

  • Induction: Initial dosing under medical supervision, requiring the patient to be in early withdrawal
  • Stabilization: Dose adjustment until cravings and withdrawal are minimal, usually one to two months
  • Maintenance: Stable dosing for an extended period — often a year or longer — combined with counseling and behavioral therapy

Evidence consistently shows that longer treatment durations are associated with better outcomes. Most addiction medicine experts recommend a minimum of one to two years of maintenance therapy.

Find a Suboxone Clinic Near You — OBOT & Telehealth Options

Finding a Suboxone clinic has become significantly easier since the federal government eliminated the X-waiver requirement in January 2023, meaning any provider with a standard DEA license can now prescribe Suboxone. Patients can search SAMHSA's treatment locator at findtreatment.gov or use our directory to locate nearby facilities that offer buprenorphine-based treatment.

Suboxone Doctors Near Me

Beyond SAMHSA's locator, many state health departments maintain directories of addiction treatment providers. Telehealth has dramatically expanded access — several platforms now offer virtual Suboxone consultations, which is especially valuable for patients in rural areas. When selecting a provider, look for those offering comprehensive treatment including counseling, not just medication prescriptions.

Suboxone Withdrawal and Tapering

Suboxone withdrawal can include muscle aches, anxiety, insomnia, nausea, sweating, and intense opioid cravings. A gradual, medically supervised taper is recommended — typically reducing the dose by 10 to 25 percent every one to four weeks. Slower tapers over several months produce fewer symptoms and lower relapse rates. There is no medically mandated time limit for Suboxone treatment, and many patients benefit from indefinite maintenance.

Suboxone vs Methadone

Suboxone can be prescribed in office settings and taken at home, carries lower overdose risk due to its ceiling effect, and offers greater scheduling flexibility. Methadone is a full agonist that may be more effective for severe, long-standing dependence but must be dispensed at licensed clinics with daily visits. Neither is inherently superior — the best choice keeps the patient in treatment. Some patients may also benefit from naltrexone, a non-opioid alternative.

Sublocade: Monthly Buprenorphine Injection

Sublocade delivers buprenorphine as a once-monthly subcutaneous injection in the abdominal area using the ATRIGEL delivery system, which forms a solid biodegradable depot that slowly releases medication. Patients must first stabilize on sublingual buprenorphine (8 mg+ daily) for at least seven days. Treatment typically begins with two 300 mg injections, followed by maintenance on 300 mg or 100 mg. Sublocade eliminates concerns about daily adherence, missed doses, and medication diversion.

Sublocade Side Effects

The most common Sublocade side effects are injection-site reactions (pain, itching, redness, or a noticeable lump), nausea, constipation, headache, and fatigue. The injection-site lump is normal and gradually diminishes as medication is absorbed. Patients should avoid rubbing or massaging the site. Elevated liver enzymes may also occur but are usually mild and transient.

Subutex: Buprenorphine Without Naloxone

Subutex was the original brand-name buprenorphine product. While the brand has been discontinued, generic buprenorphine-only tablets remain available. Buprenorphine monotherapy is typically reserved for pregnant patients (to avoid naloxone exposure to the fetus), patients with documented naloxone sensitivity, or sometimes during the induction phase before transitioning to the combination product.

Subutex vs Suboxone

The primary difference is the absence of naloxone in Subutex. Because Subutex lacks the abuse-deterrent naloxone component, it may carry slightly higher diversion risk, and many insurance formularies prioritize the combination as the default. Current clinical guidelines favor buprenorphine-only formulations primarily for pregnancy and naloxone sensitivity.

Zubsolv: Alternative Buprenorphine Brand

Zubsolv is a buprenorphine-naloxone sublingual tablet featuring a mint flavor and faster dissolution (under two minutes). Due to enhanced bioavailability, Zubsolv uses different dose strengths — a 5.7 mg/1.4 mg tablet equals a Suboxone 8 mg/2 mg dose. Zubsolv is available in multiple strengths for flexible dosing during both induction and maintenance.

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Medically Reviewed Updated September 2026

Reviewed by licensed addiction specialists. Information reflects current clinical guidance.

Sources:SAMHSA·NIDA·CDC

Need immediate help? Call SAMHSA: 1-800-662-4357 (24/7, free)