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Updated: July 2026
Sources: SAMHSA, NIDA

Suboxone Clinic Near You: Buprenorphine Treatment for Opioid Addiction

Find a Suboxone clinic near you. Buprenorphine — sold under brand names Suboxone, Sublocade, Subutex, Zubsolv, and Brixadi — is the most-prescribed MAT for opioid use disorder. It is a partial mu-opioid agonist with a ceiling effect that dramatically reduces overdose risk vs. methadone. After the MAT Act of 2023 eliminated the X-waiver requirement, any licensed prescriber can prescribe buprenorphine in office-based settings (OBOT), via telehealth, or at retail pharmacies. Buprenorphine is a Schedule III controlled substance and is covered by Medicaid in all 50 states.

Found 7,145 treatment centers offering buprenorphine (suboxone) across the United States.

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Clearbrook Treatment Center MA LLC

Clearbrook Treatment Center MA LLC, located in Baldwinville, MA, provides extensive care for adults and young adults struggling with addiction. They offer various levels of care, including extended residential stays, outpatient services, and inpatient detox, all customized to each person's specific requirements. Utilizing methodologies such as 12-step program support, techniques for managing anger, and brief intervention strategies, Clearbrook prioritizes creating a unique treatment path for everyone. The facility is particularly adept at addressing dual diagnoses of substance abuse and mental health conditions, guaranteeing high-standard treatment through its distinct focus on personalized plans. Catering to both men and women, Clearbrook Treatment Center MA LLC is committed to guiding individuals toward sustained sobriety.

Clearfield Comp Treatment Ctr

Clearfield Comp Treatment Ctr, situated in Clearfield, PA, delivers tailored programs for individuals and adolescents struggling with substance use disorders. The center provides intensive outpatient care, general outpatient services, and medication-assisted treatment options including methadone, buprenorphine, or naltrexone. Employing strategies like 12-step facilitation, anger management, and brief interventions, they serve adult men and women, including those affected by intimate partner or domestic violence. Clearfield Comp Treatment Ctr is dedicated to offering personalized support for all clients, male and female, establishing itself as a thorough resource for addiction recovery in the region.

Clearview at Riverview Reg Med Ctr

Clearview at Riverview Reg Med Ctr, located in Gadsden, AL, provides thorough inpatient detoxification within a hospital setting. Their recovery support includes 12-step facilitation, anger management techniques, and brief intervention strategies. The center accommodates specific needs with specialized tracks for active military duty, adult men, and adult women. Clearview serves adults and young adults of all genders, ensuring a secure and encouraging atmosphere for healing. For those needing effective detoxification with an emphasis on personalized treatment and tailored programs, this establishment delivers a customized recovery path.

ClearVision Health and Wellness LLC

ClearVision Health and Wellness LLC, located in Hazleton, PA, provides a wide range of detox and substance use treatment options. The center features hospital-based inpatient detox services, round-the-clock care, and residential detox programs. It employs a diverse array of methods, such as 12-step programs, anger management strategies, and short intervention techniques. Additionally, there are specialized offerings for active duty military members, as well as tailored programs for adult men and women. With a commitment to serving adults and seniors of all backgrounds, ClearVision Health and Wellness LLC prioritizes personalized, high-quality treatment. This facility represents a supportive refuge for those on their journey toward overcoming addiction.

Clement J Zablocki VAMC

The Clement J Zablocki VAMC, situated in Milwaukee, WI, delivers extensive programs for overcoming addiction. They provide hospital-based inpatient detox and treatment, with tailored care for adult men and women, survivors of intimate partner violence, and domestic violence victims. Utilizing approaches like 12-step facilitation, anger management, and brief interventions, this center supports adults and young adults across all genders. From detox and substance use treatment to help with transitional housing, Clement J Zablocki VAMC delivers excellent care and assistance for individuals pursuing sobriety.

Cleveland Clinic
Cleveland, OH

Situated in Cleveland, OH, the Cleveland Clinic delivers extensive addiction treatment options for both adults and adolescents. This center features inpatient detoxification services, around-the-clock hospital care, and intensive outpatient programs. Utilizing proven methods like 12-step facilitation, brief interventions, and cognitive behavioral therapy, the approach is grounded in evidence. The facility prioritizes personalized care, catering specifically to those grappling with simultaneous substance use and mental health issues. With specialized programs designed for both men and women, Cleveland Clinic provides quality, tailored treatment that addresses the distinct needs of its patients, making it a key resource for effective and individualized addiction recovery.

Cleveland Treatment Center Inc

Cleveland Treatment Center Inc, situated in Cleveland, Ohio, provides extensive outpatient programs designed for both adults and young adults dealing with substance use issues. The center features specialized programs for men, women, and those affected by intimate partner or domestic violence, ensuring personalized care. Employing methods such as 12-step facilitation, anger management, and brief interventions, it delivers a comprehensive treatment experience. The facility also offers outpatient options including methadone/buprenorphine or naltrexone treatments alongside standard outpatient services, focusing on high-quality support to aid individuals in their recovery journey.

Cliffside Malibu

Cliffside Malibu, situated in the picturesque surroundings of Malibu, California, delivers an extensive array of services designed for those pursuing recovery from substance use issues and associated mental health challenges. This center caters to both adults and young adults, emphasizing the specific requirements of men and women, particularly those who have faced intimate partner or domestic violence. Prioritizing evidence-based methodologies such as 12-step programs and anger management, Cliffside Malibu guarantees exceptional care within a hospital inpatient environment. Individuals in need of detoxification, substance use therapy, or assistance for co-occurring conditions can anticipate customized treatment strategies and empathetic support at this distinguished rehabilitation facility.

Cliffside Malibu 2

Cliffside Malibu 2, situated in Malibu, CA, delivers thorough recovery programs for individuals and adolescents facing addiction and co-occurring psychological challenges. This establishment provides round-the-clock hospital-based inpatient detoxification and care. The curriculum incorporates 12-step guidance, emotional regulation strategies, and brief counseling. Targeted programs are available for adult men and women, alongside individuals affected by domestic or intimate partner abuse. Dedicated to superior support, this center delivers tailored therapy for diverse age demographics and genders, fostering individualized and successful healing.

Clifton Springs Hosp Clinic
Clifton Springs, NY

Situated in Clifton Springs, NY, Clifton Springs Hosp Clinic delivers extensive outpatient treatment for substance use and targeted support for adults facing concurrent mental health challenges or emotional issues in children. The facility offers outpatient options such as methadone/buprenorphine and naltrexone therapies, along with standard outpatient services. Emphasizing methods like 12-step facilitation, anger management, and brief interventions, this center serves both male and female clients, including young adults. Renowned for its proficiency in addressing co-occurring disorders, Clifton Springs Hosp Clinic is distinguished by its high-quality care and individualized programs aimed at promoting long-term recovery.

Clinica Ambulatoria Aibonito

Located in Aibonito, PR, Clinica Ambulatoria Aibonito specializes in outpatient care for individuals struggling with substance use issues, including adults and children facing concurrent mental health challenges. The center's programs include focused therapies such as anger management, brief interventions, and cognitive behavioral approaches. Catering to different demographics, the facility creates customized treatment plans for adolescents, adult men, and women. With an emphasis on outpatient options for methadone, buprenorphine, or naltrexone, this center provides extensive support for those on their path to recovery. Serving both genders, Clinica Ambulatoria Aibonito is dedicated to offering personalized, high-quality care that fosters healing and supports sustainable sobriety.

Clear Skye Treatment Center

Clear Skye Treatment Center, located in Clinton, SC, provides outpatient services for individuals struggling with substance use disorders. Their offerings include medication-assisted treatment with methadone, buprenorphine, or naltrexone. The center employs evidence-based practices such as 12-step facilitation, anger management, and brief interventions. They serve adults and young adults, offering gender-inclusive care. Clear Skye Treatment Center emphasizes creating unique treatment plans designed to meet the distinct needs of every individual who seeks their assistance, ensuring a personalized and effective recovery journey.

Clinica Ambulatoria Orocovis

Situated in Orocovis, PR, Clinica Ambulatoria Orocovis delivers extensive outpatient rehabilitation options for those facing challenges related to substance abuse and concurrent mental health issues. This center focuses on outpatient treatments using methadone, buprenorphine, or naltrexone, and integrates techniques like anger management, brief interventions, and cognitive behavioral therapy to facilitate healing. The facility has specialized programs designed for adolescents, adult males, and adult females, addressing a wide variety of needs. By offering care to both adults and younger individuals, Clinica Ambulatoria Orocovis ensures that each patient receives customized treatment plans aimed at their specific circumstances, fostering a nurturing and effective journey towards sustained recovery.

Clinic 5 LLC
Columbus, OH

Clinic 5 LLC, located in Columbus, OH, provides extensive addiction recovery care within a welcoming and expert setting. This center delivers detox and drug/alcohol use disorder treatment through its outpatient, day treatment, and partial hospitalization programs. Clinic 5 LLC employs proven methods such as 12-step encouragement, quick intervention strategies, and cognitive behavioral techniques to customize recovery paths for each person. Featuring dedicated services for active military personnel, young people, and adult men, Clinic 5 LLC assists adults and older adults of any gender. Patients will receive excellent care and individualized assistance as they work toward sobriety at this location.

Clinica Ambulatoria CIMA Caguas

Clinica Ambulatoria CIMA Caguas, located in Caguas, PR, delivers outpatient substance abuse services for individuals of all ages experiencing co-occurring mental health challenges. Their expertise includes anger management, brief intervention strategies, and cognitive behavioral therapy, ensuring personalized treatment plans. The center caters to diverse groups through specialized programs for adolescents, adult males, and females, fostering a nurturing atmosphere. They offer both regular outpatient services and medication-assisted treatment options such as methadone, buprenorphine, and naltrexone. Clinica Ambulatoria CIMA Caguas is committed to providing high-quality, effective rehabilitation for both substance use and mental health concerns.

Clermont Recovery Center Inc

Clermont Recovery Center Inc, located in Batavia, OH, specializes in providing treatment for substance use and programs designed for those facing concurrent mental health challenges. The facility offers intensive outpatient treatments along with outpatient services, including options like methadone/buprenorphine and naltrexone. By implementing evidence-based strategies such as cognitive behavioral therapy and the Matrix Model, Clermont Recovery Center Inc serves adults, adolescents, and children, with particular emphasis on personalized care for women and clients with dual diagnoses. Committed to delivering high-quality care through a range of specialized programs, the center aims to assist individuals in their recovery journey.

Clinic 1
New York, NY

Situated in New York, NY, Clinic 1 provides outpatient programs specifically designed for substance use recovery for both adults and young adults. The center focuses on effective strategies such as anger management, brief interventions, and cognitive behavioral therapy to combat addiction. Clinic 1 also features tailored services for active military members, as well as programs for adult men and women, fostering a nurturing atmosphere for those on the path to recovery. With options for outpatient methadone/buprenorphine or naltrexone treatment, alongside standard outpatient services, this facility delivers top-notch support for all clients. For those seeking thorough addiction rehabilitation in a friendly environment, Clinic 1 stands out as an excellent option in New York City.

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Canoga Park, CA

Clear View Canyon Inc, located in Canoga Park, CA, delivers complete addiction recovery services for adults and adolescents struggling with dependency and co-occurring psychological conditions. The center features hospital-based inpatient detoxification and treatment, offering specialized assistance for active military personnel, adult men, and women. Employing proven methods such as cognitive behavioral therapy and 12-step facilitation, Clear View Canyon Inc guarantees excellent care adapted to individual requirements. Whether in need of detox, addiction treatment, or dual diagnosis care, individuals will find customized support in a nurturing setting. This center caters to both male and female individuals, representing a crucial avenue for those pursuing sobriety.

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Prairie City, IA

Clearview Recovery Inc, located in Prairie City, IA, specializes in holistic treatment for substance use disorders and offers targeted support for individuals facing concurrent mental health challenges. The center features various treatment options such as intensive outpatient services, long-term residential care, and traditional outpatient programs. Emphasizing 12-step approaches, anger management techniques, and brief therapeutic interventions, Clearview Recovery Inc customizes its programs to suit the unique needs of each individual. Additionally, it provides specialized services for adult women and those who have experienced intimate partner violence, domestic abuse, or sexual trauma. As a women-only facility, it provides a nurturing and secure space for adults and older individuals in their recovery journey.

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Clearview Recovery Inc, located in Newton, IA, provides extensive care for individuals struggling with addiction and offers transitional housing specifically for adult women. The center excels in addressing dual diagnoses involving substance abuse and significant mental health conditions in adults, alongside severe emotional issues in children. Emphasizing both long-term residential stays and outpatient services, Clearview Recovery Inc features tailored programs for those impacted by domestic violence, intimate partner abuse, and sexual trauma. Their treatment methodologies incorporate 12-step support, techniques for managing anger, and brief intervention techniques. Clearview Recovery Inc is dedicated to delivering individualized and successful treatment for older adults and other adults who prefer a women-only setting.

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Situated in Malibu, CA, Cliffside Malibu 3 delivers extensive addiction treatment options for both adults and young adults. This facility specializes in inpatient detox services and addresses issues related to substance use disorders, including accompanying mental health challenges. The treatment program incorporates proven methods such as 12-step support, anger management, and brief interventions. Catering to both men and women, as well as those who have encountered intimate partner or domestic abuse, Cliffside Malibu 3 emphasizes high-quality care and personalized treatment strategies aimed at fostering long-term recovery.

Frequently Asked Questions

What is buprenorphine and how does it treat opioid addiction?
Buprenorphine is a partial opioid agonist medication approved by the FDA for treating opioid use disorder. It binds to the same receptors as heroin and fentanyl but produces a much weaker effect, reducing cravings and withdrawal symptoms without causing intense euphoria. Buprenorphine has a ceiling effect, meaning its opioid effects plateau at moderate doses, making it safer than methadone in terms of overdose risk.
What is the difference between Suboxone and Subutex?
Suboxone contains two active ingredients — buprenorphine and naloxone — while Subutex contains only buprenorphine without naloxone. The naloxone in Suboxone is included as an abuse deterrent; it remains inactive when taken sublingually as prescribed but triggers withdrawal if the medication is injected. Subutex is generally reserved for patients who cannot tolerate naloxone, such as pregnant women.
What is a Sublocade injection and how does it work?
Sublocade is a once-monthly injectable form of buprenorphine administered as a subcutaneous injection in the abdominal area. After injection, the medication forms a solid deposit under the skin that slowly releases buprenorphine over the course of a month. This eliminates daily dosing and removes the possibility of missed doses or medication diversion.
What are the common side effects of Suboxone?
Common Suboxone side effects include headache, nausea, constipation, insomnia, sweating, and mouth numbness or pain from sublingual administration. Some patients also experience dizziness, drowsiness, and blurred vision, particularly when starting treatment. Most side effects diminish within the first few weeks as the body adjusts. Patients should report difficulty breathing or signs of allergic reaction immediately.
What happens during Suboxone withdrawal?
Suboxone withdrawal occurs when a patient stops taking the medication abruptly after prolonged use, with symptoms including muscle aches, anxiety, insomnia, nausea, and irritability. A medically supervised taper is strongly recommended, typically reducing the dose by small increments over weeks or months. The risk of opioid relapse is significantly higher during unsupervised discontinuation.
How does Suboxone compare to methadone?
Suboxone and methadone are both effective for opioid use disorder but differ in key ways. Methadone is a full opioid agonist dispensed daily at licensed clinics, while Suboxone is a partial agonist that can be prescribed by qualified physicians and taken at home. Suboxone carries a lower overdose risk due to its ceiling effect and offers greater convenience, though methadone may be more appropriate for patients with severe, long-standing dependence.
How can I find a Suboxone clinic or doctor near me?
The most reliable way to find a Suboxone provider is through SAMHSA's online treatment locator at findtreatment.gov, which allows you to search by location and filter for buprenorphine providers. Many primary care offices, addiction treatment centers, and telehealth platforms now offer Suboxone prescriptions following the elimination of the federal X-waiver requirement in early 2023.
What is Zubsolv and how is it different from Suboxone?
Zubsolv is a brand-name buprenorphine and naloxone sublingual tablet that features a mint flavor and dissolves faster under the tongue than other options. Due to its higher bioavailability, Zubsolv uses different dosing strengths — a Zubsolv 5.7 mg/1.4 mg tablet is considered equivalent to a Suboxone 8 mg/2 mg dose. Patients switching between products should work closely with their prescriber for correct dose conversion.
Does Medicaid cover Suboxone treatment?
Yes — Medicaid covers buprenorphine (including Suboxone, Sublocade, Subutex, Zubsolv, and Brixadi) for opioid use disorder in all 50 states, as required by the SUPPORT Act of 2018. Medicaid is the largest single payer for MAT in the US. Coverage details vary by state — some require prior authorization or limit certain formulations. Many OBOT clinics accept Medicaid directly; telehealth Suboxone providers also bill Medicaid in most states. Bring your Medicaid card to your intake appointment.
Can I get Suboxone through telehealth?
Yes. After the MAT Act of 2023 permanently eliminated the X-waiver requirement, any licensed prescriber can prescribe Suboxone via telehealth in most states. The DEA also extended COVID-era telehealth flexibilities through at least 2025, allowing virtual Suboxone induction without a prior in-person visit. Several specialty platforms — Bicycle Health, Ophelia, Workit Health, Boulder Care — offer Medicaid-accepting telehealth Suboxone treatment. Telehealth has dramatically expanded access in rural and underserved areas with no nearby OBOT physicians.

About Buprenorphine (Suboxone)

Buprenorphine is classified as a partial opioid agonist, meaning it activates opioid receptors in the brain but to a much lesser degree than full agonists such as heroin, fentanyl, or oxycodone. This partial activation suppresses withdrawal symptoms and reduces cravings without producing dangerous respiratory depression or intense euphoria. Buprenorphine also has an unusually high binding affinity for the mu-opioid receptor, effectively blocking other opioids from attaching — providing a protective effect against relapse-related overdose.

How Buprenorphine Works

One of the defining features of buprenorphine is its ceiling effect — after a certain dose threshold, increasing the amount does not produce additional opioid effects. This dramatically reduces the risk of fatal overdose compared to methadone or illicit opioids. The ceiling effect, combined with its long duration of action (24 to 72 hours), makes buprenorphine one of the safest and most effective tools in medication-assisted treatment (MAT). Approved by the FDA in 2002, buprenorphine was a breakthrough because it could be prescribed in outpatient settings rather than requiring daily clinic visits.

Buprenorphine Brand Comparison: Suboxone, Subutex, Sublocade, Zubsolv, Brixadi

Buprenorphine is available under several FDA-approved brand names, each with distinct formulations, dosing schedules, and clinical use cases. The comparison below highlights the key differences:

BrandActive ingredientFormFrequencySettingFDA yearBest for
SuboxoneBuprenorphine + naloxoneSublingual film / tabletDailyOBOT, telehealth, retail pharmacy2002Most prescribed; naloxone deters injection misuse
SubutexBuprenorphine (alone)Sublingual tabletDailyOBOT2002Pregnancy; documented naloxone sensitivity
SublocadeBuprenorphine extended-releaseSubcutaneous injection (ATRIGEL depot)MonthlyClinic-administered2017No daily dosing; eliminates diversion risk
ZubsolvBuprenorphine + naloxoneSublingual tablet (higher bioavailability)DailyOBOT2013Faster dissolution; mint flavor; lower mg/dose
BrixadiBuprenorphine extended-releaseSubcutaneous injectionWeekly or monthlyClinic2023Newer alternative to Sublocade; weekly option for induction

All five medications are Schedule III controlled substances and equivalent in clinical efficacy at appropriate doses. The choice depends on adherence patterns, lifestyle, insurance coverage, and clinical context (e.g., pregnancy, prior injection use, daily-dosing burden). Many patients begin on sublingual Suboxone for stabilization and transition to monthly Sublocade or weekly Brixadi after sustained recovery.

Buprenorphine Side Effects

Common buprenorphine side effects include:

  • Headache and dizziness
  • Nausea and vomiting, especially during induction
  • Constipation and insomnia
  • Excessive sweating
  • Mouth numbness or oral discomfort from sublingual formulations

More serious side effects may include respiratory depression (particularly when combined with benzodiazepines or alcohol), liver problems, and allergic reactions. For most patients, side effects are mild and resolve within one to two weeks. The benefits in preventing relapse and overdose death significantly outweigh the risks.

Buprenorphine Dosage and Induction

Treatment begins with an induction phase where the patient must be in mild to moderate opioid withdrawal. Common induction doses range from 2 mg to 8 mg on the first day, with increases over the following days. Most patients stabilize on 8 mg to 24 mg per day, with 16 mg being the most commonly prescribed dose. Research suggests doses of 16 mg or higher are associated with better retention and outcomes. Dosage should always be adjusted under medical supervision.

Buprenorphine/Naloxone Combination

Many buprenorphine formulations include naloxone as an abuse deterrent. When taken sublingually as directed, naloxone has very low bioavailability and produces no clinical effect. However, if someone attempts to inject the medication, the naloxone component becomes fully active and triggers severe withdrawal. This design discourages injection misuse while having no impact on patients who take the medication correctly. The combination is the standard first-line formulation for opioid addiction treatment.

Suboxone: Sublingual Buprenorphine

Suboxone is the most recognized brand name for buprenorphine-naloxone and is most commonly dispensed as a sublingual film (Suboxone strips) that dissolves under the tongue. Suboxone has transformed opioid treatment by enabling millions of patients to receive effective pharmacotherapy in outpatient settings without the daily clinic visits required by methadone programs.

Suboxone Side Effects

Commonly reported Suboxone side effects include headache, nausea, tongue or mouth irritation, constipation, insomnia, sweating, and decreased libido. The sublingual film can cause irritation or small sores inside the mouth — rotating placement between under the tongue and against the cheek helps minimize this. Patients should not eat, drink, or smoke while the film is dissolving.

Suboxone Strips: Film vs. Tablet

Suboxone strips (sublingual film) have largely replaced the original tablet form. The film dissolves more quickly (two to four minutes), provides more consistent absorption, and is harder to divert due to individual foil packaging. Generic buprenorphine-naloxone tablets are often less expensive and may be preferred for cost reasons. Both are therapeutically equivalent when taken as prescribed.

Suboxone Treatment Programs

Comprehensive Suboxone treatment typically includes three phases:

  • Induction: Initial dosing under medical supervision, requiring the patient to be in early withdrawal
  • Stabilization: Dose adjustment until cravings and withdrawal are minimal, usually one to two months
  • Maintenance: Stable dosing for an extended period — often a year or longer — combined with counseling and behavioral therapy

Evidence consistently shows that longer treatment durations are associated with better outcomes. Most addiction medicine experts recommend a minimum of one to two years of maintenance therapy.

Find a Suboxone Clinic Near You — OBOT & Telehealth Options

Finding a Suboxone clinic has become significantly easier since the federal government eliminated the X-waiver requirement in January 2023, meaning any provider with a standard DEA license can now prescribe Suboxone. Patients can search SAMHSA's treatment locator at findtreatment.gov or use our directory to locate nearby facilities that offer buprenorphine-based treatment.

Suboxone Doctors Near Me

Beyond SAMHSA's locator, many state health departments maintain directories of addiction treatment providers. Telehealth has dramatically expanded access — several platforms now offer virtual Suboxone consultations, which is especially valuable for patients in rural areas. When selecting a provider, look for those offering comprehensive treatment including counseling, not just medication prescriptions.

Suboxone Withdrawal and Tapering

Suboxone withdrawal can include muscle aches, anxiety, insomnia, nausea, sweating, and intense opioid cravings. A gradual, medically supervised taper is recommended — typically reducing the dose by 10 to 25 percent every one to four weeks. Slower tapers over several months produce fewer symptoms and lower relapse rates. There is no medically mandated time limit for Suboxone treatment, and many patients benefit from indefinite maintenance.

Suboxone vs Methadone

Suboxone can be prescribed in office settings and taken at home, carries lower overdose risk due to its ceiling effect, and offers greater scheduling flexibility. Methadone is a full agonist that may be more effective for severe, long-standing dependence but must be dispensed at licensed clinics with daily visits. Neither is inherently superior — the best choice keeps the patient in treatment. Some patients may also benefit from naltrexone, a non-opioid alternative.

Sublocade: Monthly Buprenorphine Injection

Sublocade delivers buprenorphine as a once-monthly subcutaneous injection in the abdominal area using the ATRIGEL delivery system, which forms a solid biodegradable depot that slowly releases medication. Patients must first stabilize on sublingual buprenorphine (8 mg+ daily) for at least seven days. Treatment typically begins with two 300 mg injections, followed by maintenance on 300 mg or 100 mg. Sublocade eliminates concerns about daily adherence, missed doses, and medication diversion.

Sublocade Side Effects

The most common Sublocade side effects are injection-site reactions (pain, itching, redness, or a noticeable lump), nausea, constipation, headache, and fatigue. The injection-site lump is normal and gradually diminishes as medication is absorbed. Patients should avoid rubbing or massaging the site. Elevated liver enzymes may also occur but are usually mild and transient.

Subutex: Buprenorphine Without Naloxone

Subutex was the original brand-name buprenorphine product. While the brand has been discontinued, generic buprenorphine-only tablets remain available. Buprenorphine monotherapy is typically reserved for pregnant patients (to avoid naloxone exposure to the fetus), patients with documented naloxone sensitivity, or sometimes during the induction phase before transitioning to the combination product.

Subutex vs Suboxone

The primary difference is the absence of naloxone in Subutex. Because Subutex lacks the abuse-deterrent naloxone component, it may carry slightly higher diversion risk, and many insurance formularies prioritize the combination as the default. Current clinical guidelines favor buprenorphine-only formulations primarily for pregnancy and naloxone sensitivity.

Zubsolv: Alternative Buprenorphine Brand

Zubsolv is a buprenorphine-naloxone sublingual tablet featuring a mint flavor and faster dissolution (under two minutes). Due to enhanced bioavailability, Zubsolv uses different dose strengths — a 5.7 mg/1.4 mg tablet equals a Suboxone 8 mg/2 mg dose. Zubsolv is available in multiple strengths for flexible dosing during both induction and maintenance.

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Medically Reviewed Updated July 2026

Reviewed by licensed addiction specialists. Information reflects current clinical guidance.

Sources:SAMHSA·NIDA·CDC

Need immediate help? Call SAMHSA: 1-800-662-4357 (24/7, free)