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Medically Reviewed Content
Updated: September 2026
Sources: SAMHSA, NIDA

Suboxone Clinic Near You: Buprenorphine Treatment for Opioid Addiction

Find a Suboxone clinic near you. Buprenorphine — sold under brand names Suboxone, Sublocade, Subutex, Zubsolv, and Brixadi — is the most-prescribed MAT for opioid use disorder. It is a partial mu-opioid agonist with a ceiling effect that dramatically reduces overdose risk vs. methadone. After the MAT Act of 2023 eliminated the X-waiver requirement, any licensed prescriber can prescribe buprenorphine in office-based settings (OBOT), via telehealth, or at retail pharmacies. Buprenorphine is a Schedule III controlled substance and is covered by Medicaid in all 50 states.

Found 7,094 treatment centers offering buprenorphine (suboxone) across the United States.

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Compassionate Recovery Care

Compassionate Recovery Care, located in Hermitage, TN, provides comprehensive outpatient services for individuals struggling with substance use disorders. Their expertise extends to treating co-occurring mental health challenges in adults and emotional disturbances in children. Utilizing personalized therapeutic strategies like anger management, brief intervention, and cognitive behavioral therapy, the center crafts treatment plans that address the specific requirements of each client. This individualized approach is designed for adults and young adults across all gender identities. Outpatient offerings at Compassionate Recovery Care encompass detoxification and medication-assisted treatment options including methadone, buprenorphine, or naltrexone. The facility is dedicated to delivering high-quality, customized care to every individual they serve.

Complete Hlthcare Addiction/Gynecology

Complete Hlthcare Addiction/Gynecology located in Pickerington, OH, offers a wide range of addiction treatment options for both adults and seniors. This center specializes in detoxification, substance use disorder therapies, and offers targeted support for individuals dealing with dual diagnoses of substance abuse and significant mental health issues, as well as emotional challenges in children. With an emphasis on methods such as 12-step programs, anger management, and brief intervention strategies, the center serves a diverse population, including military personnel, teenagers, and adult males. Whether offering intensive outpatient programs or structured outpatient services, the facility is dedicated to providing personalized care that meets the unique needs of each individual.

Complete Hlthcare Addiction/Gynecology

Situated in Columbus, OH, Complete Hlthcare Addiction/Gynecology delivers an extensive array of services for addiction and mental health issues. The facility specializes in detox services, treatment for substance use disorders, and focused care for patients facing both substance use challenges and significant mental health conditions. It offers various treatment formats such as intensive outpatient, outpatient, and daytime programs. Emphasizing methods like 12-step support, anger control, and brief intervention strategies, this center serves a diverse clientele, including active military personnel, teenagers, adult men and women, as well as seniors. With customized treatment plans for both genders, the center is committed to providing exceptional, personalized care for those on the path to recovery and improved well-being.

Complete Hlthcare Addiction/Gynecology

Based in Columbus, OH, Complete Hlthcare Addiction/Gynecology is a multifaceted rehabilitation facility that provides a variety of treatment alternatives. The center addresses detoxification, substance abuse issues, and co-occurring mental health disorders for both adults and children. They offer a range of programs including intensive outpatient, outpatient, and day treatment to meet diverse needs. Employing methods such as the 12-step program, anger management sessions, and brief intervention strategies, the center prioritizes personalized care. Additionally, specialized services are available for active military personnel, adolescents, and adult males. Catering to adults and seniors of all genders, this facility delivers high-quality care with an emphasis on customized treatment plans to aid individuals in their recovery processes.

Comprehensive Wellness Centers

Comprehensive Wellness Centers, located in Lake Worth, FL, provides a variety of top-notch rehabilitation services designed for both adults and young adults. The center specializes in intensive outpatient care, long-term residential treatment, and customized outpatient programs that align with individual requirements. Emphasizing 12-step approaches, anger management, and short intervention methods, this facility focuses on addressing substance abuse issues as well as concurrent mental health disorders. It features specialized programs for active duty military individuals, men, and women. With additional offerings such as transitional housing and sober living arrangements, the center fosters a nurturing environment for recovery. Committed to delivering effective and compassionate support, Comprehensive Wellness Centers is a reliable option for those pursuing meaningful rehabilitation results.

Concerted Care Group

Concerted Care Group, located in Frederick, MD, provides focused treatment for substance use through a range of options including intensive outpatient programs, standard outpatient services, and specialized programs utilizing methadone, buprenorphine, or naltrexone. Their methodology incorporates 12-step support, anger management strategies, and brief intervention methods. The center serves adult men and women, including those who have faced intimate partner or domestic violence. Catering to both adults and young adults of all genders, Concerted Care Group emphasizes personalized care in a nurturing setting. Committed to delivering high-quality, individualized treatment, this center aims to assist individuals in achieving sustained recovery from substance use challenges.

Concerted Care Group

Concerted Care Group, located in Baltimore, MD, delivers focused addiction recovery services in several modalities, including intensive outpatient, standard outpatient, and medication-assisted treatment (methadone/buprenorphine/naltrexone). Their individualized treatment plans incorporate strategies like 12-step facilitation, anger management, and brief interventions. This center features distinct programs designed for adult males, adult females, and individuals affected by intimate partner or domestic violence. Catering to adults and young adults of both genders, Concerted Care Group is committed to offering impactful and complete care for substance use disorders.

Concerted Care Group LLC

Concerted Care Group LLC, located in Brooklyn, MD, is a prominent rehabilitation center dedicated to treating substance use disorders. This facility provides a range of services, including intensive outpatient treatment, general outpatient care, and specialized outpatient options involving methadone, buprenorphine, or naltrexone. Emphasizing approaches like 12-step facilitation, anger management, and brief interventions, the center customizes its programs to meet the needs of adult men and women, as well as clients affected by domestic or intimate partner violence. Catering to both adults and young adults, Concerted Care Group LLC is committed to delivering effective support and assistance for those on their recovery journey from substance dependence.

Concord Hospital
Concord, NH

Concord Hospital, located in Concord, NH, provides extensive treatment for substance use disorders as well as dedicated care for those dealing with concurrent substance use and significant mental health issues. The facility offers outpatient options, including methadone and buprenorphine therapies, along with consistent outpatient programs. Utilizing proven methods like cognitive behavioral therapy and motivational interviewing, Concord Hospital features distinctive programs designed for adult males and females, in addition to children and teenagers. By offering personalized assistance for different demographics, this center guarantees high-quality support for everyone pursuing recovery from addiction and mental health struggles.

Conexiones
Tewksbury, MA

Situated in Tewksbury, MA, Conexiones delivers thorough addiction recovery care across multiple settings, encompassing hospital inpatient, residential, and brief residential options. Their scientifically proven methods, including 12-step facilitation, anger management, and brief intervention, guarantee customized support for every person. This establishment accommodates various groups with dedicated programs for military personnel, adult males, and adult females. Serving adults and young adults of all genders, Conexiones cultivates a nurturing atmosphere for healing. Prioritizing exceptional care and individualized treatment strategies, this institution stands out as a premier destination for those pursuing effective rehabilitation from substance dependency.

Comprehensive Behavior Health Center

Situated in East Saint Louis, IL, the Comprehensive Behavior Health Center delivers an array of targeted therapies. Their offerings include programs for substance use disorders, transitional living arrangements, and treatment for those dealing with both substance use and severe mental health issues. The center features options for long-term residential support, outpatient care, as well as outpatient treatment utilizing methadone, buprenorphine, or naltrexone. Utilizing techniques like 12-step facilitation, brief interventions, and cognitive behavioral therapy, the center serves adults, teenagers, and active military members. Customized programs are designed for men, women, and various age demographics. Committed to providing effective care for those on the path to recovery, this facility is recognized for its thorough and personalized treatment services.

Comprehensive and Psych Associates LLC

Comprehensive and Psych Associates LLC, situated in Laurel, MD, provides targeted outpatient care for adults dealing with substance use and co-occurring mental health issues, as well as emotional challenges in children. Emphasizing personalized treatment, the center offers outpatient options including methadone, buprenorphine, and naltrexone along with standard outpatient services. It features distinctive programs such as 12-step support, anger management, and brief interventions, catering to both adults and young clients. With gender-specific services available, this center commits to delivering a thorough and customized treatment journey for everyone in pursuit of effective recovery solutions.

Conewago Snyder
Beavertown, PA

In Beavertown, PA, Conewago Snyder stands as a facility providing extensive support for overcoming addiction. This center delivers long-term stays, on-site detox, and round-the-clock residential assistance. Their specialized approaches include guidance in the 12-step model, strategies for managing anger, and brief intervention techniques, all designed to be customized for each person's recovery journey. Conewago Snyder welcomes adults, both male and female, and also offers specific support for those affected by domestic violence, serving a broad spectrum of individuals. They further aid in recovery by providing housing that supports the transition to independent living and maintains sober environments, ensuring a complete care pathway. Conewago Snyder is devoted to delivering high-quality, individualized care, aiming to guide adults and young adults toward sustained freedom from substance dependency.

Comprehensive Healthcare

Situated in Pasco, WA, Comprehensive Healthcare provides a variety of focused treatment options for those dealing with substance use and mental health challenges. The center offers intensive outpatient, outpatient, and standard outpatient programs designed to meet the unique needs of both adults and children/adolescents. Employing proven methodologies such as cognitive behavioral therapy and motivational interviewing, this facility serves individuals of all genders and includes specialized programs for younger clients as well as those facing dual diagnoses. With an emphasis on high-quality care and personalized treatment plans, the center is an important asset for individuals looking for thorough rehabilitation support.

Concourse Medical Center Inc

Concourse Medical Center Inc, situated in the Bronx, NY, provides an extensive array of outpatient treatment for substance use disorders, catering to both adults and young adults. The center is particularly focused on addressing co-occurring substance use and significant mental health challenges, including emotional issues in children. It employs a variety of evidence-based techniques, such as anger management, cognitive behavioral therapy, and short-term interventions. Programs designed specifically for adult men, women, and those who have suffered from intimate partner or domestic violence are offered. Emphasizing high-quality care, the center administers outpatient methadone/buprenorphine or naltrexone therapies in a nurturing environment for all clients.

Conewago Place
Hummelstown, PA

Conewago Place, located in Hummelstown, PA, provides distinct alcohol and drug treatment options such as extended stay, brief stay, and around-the-clock residential care. Their approach to personalized recovery involves methods like 12-step integration, emotional regulation training, and concise counseling. Specific services are available for adult men, adult women, and those affected by domestic or intimate partner abuse. Conewago Place supports adult and adolescent clients of all genders, fostering a complete and supportive atmosphere for healing. Committed to excellent service and customized therapy, the center aims to guide individuals toward lasting sobriety.

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Compassionate Wellness Center LLC, located in Hagerstown, MD, delivers tailored substance abuse care for adults facing concurrent serious mental health conditions or emotional difficulties in young individuals. Their services encompass intensive outpatient and outpatient levels of care, featuring medication-assisted treatment options such as methadone, buprenorphine, or naltrexone. Employing techniques like anger management, brief intervention strategies, and cognitive behavioral therapy, this establishment is equipped to serve active military members, teenagers, and adult males. Catering to a broad demographic of adults and older adults across all genders, Compassionate Wellness Center LLC is dedicated to providing personalized treatment plans and evidence-informed methods to foster enduring recovery.

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Comprehensive Healthcare, situated in Yakima, WA, delivers extensive addiction treatment options for both adults and young adults facing challenges with substance use and concurrent mental health issues. The center features various programs including hospital inpatient, long-term residential care, and round-the-clock residential support, employing effective methods such as 12-step facilitation, cognitive behavioral therapy, and brief interventions. With tailored programs designed for adult men, adult women, and individuals who have experienced intimate partner violence, this center addresses a wide range of needs. Providing exceptional care for all clients, this facility is recognized as a reliable source of comprehensive rehabilitation services within the Yakima community.

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Situated in Miami, FL, the Comprehensive Psychiatric Center delivers targeted outpatient services aimed at detoxification and the treatment of substance use disorders. Emphasizing relapse prevention and customized counseling for substance use disorders, this center adopts a holistic strategy for recovery. Individuals can benefit from outpatient detoxification, treatments with methadone, buprenorphine, or naltrexone, along with telemedicine and telehealth options. Customized programs are available for adults and young adults across all genders. The facility is dedicated to offering personalized care and implementing evidence-based methods, guaranteeing exceptional treatment for those in need of support for addiction.

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The Comprehensive Psychiatric Center, situated in Miami, FL, provides a full spectrum of services including outpatient detoxification, addiction recovery programs, and tailored support for adults and young adults. Their expertise lies in relapse prevention strategies and counseling for individuals struggling with substance use disorders. To ensure accessibility, they also offer remote therapy options. This center prioritizes a personalized treatment experience for all clients, regardless of gender, who are seeking effective addiction care. For those requiring immediate detox or sustained therapy for substance abuse, the Comprehensive Psychiatric Center delivers a thorough and individualized approach to healing.

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Pottsville, PA

Conewago Pottsville is a prominent rehabilitation center located in Pottsville, PA, that provides various substance use treatment options, including long-term and short-term residential programs, as well as 24-hour care. This facility emphasizes 12-step support, anger management strategies, and brief intervention methods, catering specifically to adult men, women, and individuals affected by domestic or intimate partner violence. Focusing on a diverse clientele of adults and young adults, Conewago Pottsville prioritizes personalized treatment approaches and a nurturing atmosphere for recovery. Discover exceptional care and specialized programs at this center, committed to assisting individuals in overcoming addiction and reclaiming their lives.

Frequently Asked Questions

What is buprenorphine and how does it treat opioid addiction?
Buprenorphine is a partial opioid agonist medication approved by the FDA for treating opioid use disorder. It binds to the same receptors as heroin and fentanyl but produces a much weaker effect, reducing cravings and withdrawal symptoms without causing intense euphoria. Buprenorphine has a ceiling effect, meaning its opioid effects plateau at moderate doses, making it safer than methadone in terms of overdose risk.
What is the difference between Suboxone and Subutex?
Suboxone contains two active ingredients — buprenorphine and naloxone — while Subutex contains only buprenorphine without naloxone. The naloxone in Suboxone is included as an abuse deterrent; it remains inactive when taken sublingually as prescribed but triggers withdrawal if the medication is injected. Subutex is generally reserved for patients who cannot tolerate naloxone, such as pregnant women.
What is a Sublocade injection and how does it work?
Sublocade is a once-monthly injectable form of buprenorphine administered as a subcutaneous injection in the abdominal area. After injection, the medication forms a solid deposit under the skin that slowly releases buprenorphine over the course of a month. This eliminates daily dosing and removes the possibility of missed doses or medication diversion.
What are the common side effects of Suboxone?
Common Suboxone side effects include headache, nausea, constipation, insomnia, sweating, and mouth numbness or pain from sublingual administration. Some patients also experience dizziness, drowsiness, and blurred vision, particularly when starting treatment. Most side effects diminish within the first few weeks as the body adjusts. Patients should report difficulty breathing or signs of allergic reaction immediately.
What happens during Suboxone withdrawal?
Suboxone withdrawal occurs when a patient stops taking the medication abruptly after prolonged use, with symptoms including muscle aches, anxiety, insomnia, nausea, and irritability. A medically supervised taper is strongly recommended, typically reducing the dose by small increments over weeks or months. The risk of opioid relapse is significantly higher during unsupervised discontinuation.
How does Suboxone compare to methadone?
Suboxone and methadone are both effective for opioid use disorder but differ in key ways. Methadone is a full opioid agonist dispensed daily at licensed clinics, while Suboxone is a partial agonist that can be prescribed by qualified physicians and taken at home. Suboxone carries a lower overdose risk due to its ceiling effect and offers greater convenience, though methadone may be more appropriate for patients with severe, long-standing dependence.
How can I find a Suboxone clinic or doctor near me?
The most reliable way to find a Suboxone provider is through SAMHSA's online treatment locator at findtreatment.gov, which allows you to search by location and filter for buprenorphine providers. Many primary care offices, addiction treatment centers, and telehealth platforms now offer Suboxone prescriptions following the elimination of the federal X-waiver requirement in early 2023.
What is Zubsolv and how is it different from Suboxone?
Zubsolv is a brand-name buprenorphine and naloxone sublingual tablet that features a mint flavor and dissolves faster under the tongue than other options. Due to its higher bioavailability, Zubsolv uses different dosing strengths — a Zubsolv 5.7 mg/1.4 mg tablet is considered equivalent to a Suboxone 8 mg/2 mg dose. Patients switching between products should work closely with their prescriber for correct dose conversion.
Does Medicaid cover Suboxone treatment?
Yes — Medicaid covers buprenorphine (including Suboxone, Sublocade, Subutex, Zubsolv, and Brixadi) for opioid use disorder in all 50 states, as required by the SUPPORT Act of 2018. Medicaid is the largest single payer for MAT in the US. Coverage details vary by state — some require prior authorization or limit certain formulations. Many OBOT clinics accept Medicaid directly; telehealth Suboxone providers also bill Medicaid in most states. Bring your Medicaid card to your intake appointment.
Can I get Suboxone through telehealth?
Yes. After the MAT Act of 2023 permanently eliminated the X-waiver requirement, any licensed prescriber can prescribe Suboxone via telehealth in most states. The DEA also extended COVID-era telehealth flexibilities through at least 2025, allowing virtual Suboxone induction without a prior in-person visit. Several specialty platforms — Bicycle Health, Ophelia, Workit Health, Boulder Care — offer Medicaid-accepting telehealth Suboxone treatment. Telehealth has dramatically expanded access in rural and underserved areas with no nearby OBOT physicians.

About Buprenorphine (Suboxone)

Buprenorphine is classified as a partial opioid agonist, meaning it activates opioid receptors in the brain but to a much lesser degree than full agonists such as heroin, fentanyl, or oxycodone. This partial activation suppresses withdrawal symptoms and reduces cravings without producing dangerous respiratory depression or intense euphoria. Buprenorphine also has an unusually high binding affinity for the mu-opioid receptor, effectively blocking other opioids from attaching — providing a protective effect against relapse-related overdose.

How Buprenorphine Works

One of the defining features of buprenorphine is its ceiling effect — after a certain dose threshold, increasing the amount does not produce additional opioid effects. This dramatically reduces the risk of fatal overdose compared to methadone or illicit opioids. The ceiling effect, combined with its long duration of action (24 to 72 hours), makes buprenorphine one of the safest and most effective tools in medication-assisted treatment (MAT). Approved by the FDA in 2002, buprenorphine was a breakthrough because it could be prescribed in outpatient settings rather than requiring daily clinic visits.

Buprenorphine Brand Comparison: Suboxone, Subutex, Sublocade, Zubsolv, Brixadi

Buprenorphine is available under several FDA-approved brand names, each with distinct formulations, dosing schedules, and clinical use cases. The comparison below highlights the key differences:

BrandActive ingredientFormFrequencySettingFDA yearBest for
SuboxoneBuprenorphine + naloxoneSublingual film / tabletDailyOBOT, telehealth, retail pharmacy2002Most prescribed; naloxone deters injection misuse
SubutexBuprenorphine (alone)Sublingual tabletDailyOBOT2002Pregnancy; documented naloxone sensitivity
SublocadeBuprenorphine extended-releaseSubcutaneous injection (ATRIGEL depot)MonthlyClinic-administered2017No daily dosing; eliminates diversion risk
ZubsolvBuprenorphine + naloxoneSublingual tablet (higher bioavailability)DailyOBOT2013Faster dissolution; mint flavor; lower mg/dose
BrixadiBuprenorphine extended-releaseSubcutaneous injectionWeekly or monthlyClinic2023Newer alternative to Sublocade; weekly option for induction

All five medications are Schedule III controlled substances and equivalent in clinical efficacy at appropriate doses. The choice depends on adherence patterns, lifestyle, insurance coverage, and clinical context (e.g., pregnancy, prior injection use, daily-dosing burden). Many patients begin on sublingual Suboxone for stabilization and transition to monthly Sublocade or weekly Brixadi after sustained recovery.

Buprenorphine Side Effects

Common buprenorphine side effects include:

  • Headache and dizziness
  • Nausea and vomiting, especially during induction
  • Constipation and insomnia
  • Excessive sweating
  • Mouth numbness or oral discomfort from sublingual formulations

More serious side effects may include respiratory depression (particularly when combined with benzodiazepines or alcohol), liver problems, and allergic reactions. For most patients, side effects are mild and resolve within one to two weeks. The benefits in preventing relapse and overdose death significantly outweigh the risks.

Buprenorphine Dosage and Induction

Treatment begins with an induction phase where the patient must be in mild to moderate opioid withdrawal. Common induction doses range from 2 mg to 8 mg on the first day, with increases over the following days. Most patients stabilize on 8 mg to 24 mg per day, with 16 mg being the most commonly prescribed dose. Research suggests doses of 16 mg or higher are associated with better retention and outcomes. Dosage should always be adjusted under medical supervision.

Buprenorphine/Naloxone Combination

Many buprenorphine formulations include naloxone as an abuse deterrent. When taken sublingually as directed, naloxone has very low bioavailability and produces no clinical effect. However, if someone attempts to inject the medication, the naloxone component becomes fully active and triggers severe withdrawal. This design discourages injection misuse while having no impact on patients who take the medication correctly. The combination is the standard first-line formulation for opioid addiction treatment.

Suboxone: Sublingual Buprenorphine

Suboxone is the most recognized brand name for buprenorphine-naloxone and is most commonly dispensed as a sublingual film (Suboxone strips) that dissolves under the tongue. Suboxone has transformed opioid treatment by enabling millions of patients to receive effective pharmacotherapy in outpatient settings without the daily clinic visits required by methadone programs.

Suboxone Side Effects

Commonly reported Suboxone side effects include headache, nausea, tongue or mouth irritation, constipation, insomnia, sweating, and decreased libido. The sublingual film can cause irritation or small sores inside the mouth — rotating placement between under the tongue and against the cheek helps minimize this. Patients should not eat, drink, or smoke while the film is dissolving.

Suboxone Strips: Film vs. Tablet

Suboxone strips (sublingual film) have largely replaced the original tablet form. The film dissolves more quickly (two to four minutes), provides more consistent absorption, and is harder to divert due to individual foil packaging. Generic buprenorphine-naloxone tablets are often less expensive and may be preferred for cost reasons. Both are therapeutically equivalent when taken as prescribed.

Suboxone Treatment Programs

Comprehensive Suboxone treatment typically includes three phases:

  • Induction: Initial dosing under medical supervision, requiring the patient to be in early withdrawal
  • Stabilization: Dose adjustment until cravings and withdrawal are minimal, usually one to two months
  • Maintenance: Stable dosing for an extended period — often a year or longer — combined with counseling and behavioral therapy

Evidence consistently shows that longer treatment durations are associated with better outcomes. Most addiction medicine experts recommend a minimum of one to two years of maintenance therapy.

Find a Suboxone Clinic Near You — OBOT & Telehealth Options

Finding a Suboxone clinic has become significantly easier since the federal government eliminated the X-waiver requirement in January 2023, meaning any provider with a standard DEA license can now prescribe Suboxone. Patients can search SAMHSA's treatment locator at findtreatment.gov or use our directory to locate nearby facilities that offer buprenorphine-based treatment.

Suboxone Doctors Near Me

Beyond SAMHSA's locator, many state health departments maintain directories of addiction treatment providers. Telehealth has dramatically expanded access — several platforms now offer virtual Suboxone consultations, which is especially valuable for patients in rural areas. When selecting a provider, look for those offering comprehensive treatment including counseling, not just medication prescriptions.

Suboxone Withdrawal and Tapering

Suboxone withdrawal can include muscle aches, anxiety, insomnia, nausea, sweating, and intense opioid cravings. A gradual, medically supervised taper is recommended — typically reducing the dose by 10 to 25 percent every one to four weeks. Slower tapers over several months produce fewer symptoms and lower relapse rates. There is no medically mandated time limit for Suboxone treatment, and many patients benefit from indefinite maintenance.

Suboxone vs Methadone

Suboxone can be prescribed in office settings and taken at home, carries lower overdose risk due to its ceiling effect, and offers greater scheduling flexibility. Methadone is a full agonist that may be more effective for severe, long-standing dependence but must be dispensed at licensed clinics with daily visits. Neither is inherently superior — the best choice keeps the patient in treatment. Some patients may also benefit from naltrexone, a non-opioid alternative.

Sublocade: Monthly Buprenorphine Injection

Sublocade delivers buprenorphine as a once-monthly subcutaneous injection in the abdominal area using the ATRIGEL delivery system, which forms a solid biodegradable depot that slowly releases medication. Patients must first stabilize on sublingual buprenorphine (8 mg+ daily) for at least seven days. Treatment typically begins with two 300 mg injections, followed by maintenance on 300 mg or 100 mg. Sublocade eliminates concerns about daily adherence, missed doses, and medication diversion.

Sublocade Side Effects

The most common Sublocade side effects are injection-site reactions (pain, itching, redness, or a noticeable lump), nausea, constipation, headache, and fatigue. The injection-site lump is normal and gradually diminishes as medication is absorbed. Patients should avoid rubbing or massaging the site. Elevated liver enzymes may also occur but are usually mild and transient.

Subutex: Buprenorphine Without Naloxone

Subutex was the original brand-name buprenorphine product. While the brand has been discontinued, generic buprenorphine-only tablets remain available. Buprenorphine monotherapy is typically reserved for pregnant patients (to avoid naloxone exposure to the fetus), patients with documented naloxone sensitivity, or sometimes during the induction phase before transitioning to the combination product.

Subutex vs Suboxone

The primary difference is the absence of naloxone in Subutex. Because Subutex lacks the abuse-deterrent naloxone component, it may carry slightly higher diversion risk, and many insurance formularies prioritize the combination as the default. Current clinical guidelines favor buprenorphine-only formulations primarily for pregnancy and naloxone sensitivity.

Zubsolv: Alternative Buprenorphine Brand

Zubsolv is a buprenorphine-naloxone sublingual tablet featuring a mint flavor and faster dissolution (under two minutes). Due to enhanced bioavailability, Zubsolv uses different dose strengths — a 5.7 mg/1.4 mg tablet equals a Suboxone 8 mg/2 mg dose. Zubsolv is available in multiple strengths for flexible dosing during both induction and maintenance.

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Medically Reviewed Updated September 2026

Reviewed by licensed addiction specialists. Information reflects current clinical guidance.

Sources:SAMHSA·NIDA·CDC

Need immediate help? Call SAMHSA: 1-800-662-4357 (24/7, free)