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Medically Reviewed Content
Updated: September 2026
Sources: SAMHSA, NIDA

Suboxone Clinic Near You: Buprenorphine Treatment for Opioid Addiction

Find a Suboxone clinic near you. Buprenorphine — sold under brand names Suboxone, Sublocade, Subutex, Zubsolv, and Brixadi — is the most-prescribed MAT for opioid use disorder. It is a partial mu-opioid agonist with a ceiling effect that dramatically reduces overdose risk vs. methadone. After the MAT Act of 2023 eliminated the X-waiver requirement, any licensed prescriber can prescribe buprenorphine in office-based settings (OBOT), via telehealth, or at retail pharmacies. Buprenorphine is a Schedule III controlled substance and is covered by Medicaid in all 50 states.

Found 7,094 treatment centers offering buprenorphine (suboxone) across the United States.

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Crossroads of Oak Ridge

Crossroads of Oak Ridge, located in Oak Ridge, TN, provides targeted outpatient treatment to address substance use issues for both adults and young adults. The center offers a variety of treatment modalities, which include outpatient options such as methadone, buprenorphine, or naltrexone therapy, traditional outpatient services, and remote care through telemedicine. It also emphasizes the needs of pregnant and postpartum women, delivering thorough support for this demographic. Focusing on counseling for substance use disorders, Crossroads of Oak Ridge creates customized treatment plans for male and female clients alike. Its dedication to high-quality, personalized care positions it as an essential option for individuals in search of effective addiction recovery solutions.

Crossroads Treatment Centers

Crossroads Treatment Centers located in Columbia, SC, provides outpatient detox and rehabilitation services specifically designed for adults and young adults. The center features distinct programs aimed at pregnant or postpartum women, delivering well-rounded care to address their unique requirements. With an emphasis on preventing relapse, the facility offers counseling for substance use disorders as well as telehealth therapy options. Crossroads Treatment Centers prioritizes high-quality, research-backed methods to facilitate recovery. Catering to both men and women, the center also offers outpatient treatment using methadone, buprenorphine, or naltrexone, fostering a nurturing atmosphere for those striving to break free from addiction.

Crossroads Treatment Centers

Crossroads Treatment Centers in Memphis, TN, provides comprehensive outpatient services for individuals battling substance use disorders. Their expertise lies in medication-assisted treatment options, including methadone, buprenorphine, and naltrexone. Clients can also access individual and group counseling, as well as telehealth services for added convenience. A distinctive feature of this center is its dedicated program designed for pregnant and postpartum individuals. Crossroads Treatment Centers welcomes adult men and women, offering specialized, gender-affirming care to support each person's unique path to recovery. If you or someone you know requires dedicated and tailored addiction treatment, this facility is committed to guiding you toward lasting wellness.

Crossroads Treatment Centers

Crossroads Treatment Centers in Knoxville, TN, delivers accessible outpatient substance abuse recovery programs. Their approach centers on preventing setbacks and providing expert guidance for addiction. Services include medication-assisted treatment (methadone, buprenorphine, naltrexone), with the added convenience of remote counseling sessions. The center is particularly dedicated to supporting expectant and new mothers, serving adults and young adults across all gender identities. Crossroads Treatment Centers is dedicated to fostering a nurturing space for those on their journey to sobriety, with personalized care designed for individual circumstances.

Crouse Health Hospital Inc

Crouse Health Hospital Inc, located in Syracuse, NY, provides expert care for substance use disorders through its outpatient services. The center offers treatment options that include outpatient methadone/buprenorphine and naltrexone therapies, alongside general outpatient programs. Prioritizing methods such as anger management, cognitive behavioral therapy, and motivational interviewing, this facility customizes its approach to best serve individual clients. There are specialized programs available for adolescents, adult men, and adult women. Catering to individuals of all ages and genders, Crouse Health Hospital Inc ensures a nurturing atmosphere for recovery. If you are looking for effective and personalized addiction treatment, Crouse Health Hospital Inc may be the right choice for you.

Crossroads of Jacksboro

Situated in Jacksboro, TN, Crossroads of Jacksboro stands out as a prominent rehabilitation center that specializes in outpatient detox services and treatment for substance use disorders, along with tailored programs for pregnant and postpartum individuals. The facility emphasizes relapse prevention techniques, counseling for substance use issues, and the availability of telemedicine and telehealth therapy. Catering to adults and young adults of all genders, the center focuses on personalized treatment plans to cater to the distinct recovery journey of each individual. With a focus on compassion and a variety of treatment modalities, including outpatient options for methadone, buprenorphine, or naltrexone, Crossroads of Jacksboro commits itself to delivering exceptional care to those striving to conquer their addiction.

Crossroads Treatment Centers

Crossroads Treatment Centers in Charleston, SC, delivers outpatient care for individuals and young adults struggling with substance use. Services include outpatient medication-assisted treatment with methadone, buprenorphine, or naltrexone, alongside general outpatient services and remote therapy sessions. They employ the Matrix Model and offer counseling for substance use disorders. A particular focus is placed on assisting pregnant and postpartum women. The center is committed to providing individualized, high-quality, and evidence-based treatment for all clients, promoting their journey toward recovery from addiction.

Crossroads Treatment Centers

In Weaverville, NC, Crossroads Treatment Centers provides outpatient services including detoxification, addiction treatment, and medication-assisted treatment with methadone, buprenorphine, or naltrexone for adults and young adults. The center is dedicated to relapse prevention, offers counseling for substance use disorders, and utilizes telemedicine for therapy. They have a particular focus on offering specialized care for pregnant and postpartum women. Crossroads Treatment Centers serves both men and women, creating personalized and thorough treatment strategies to aid in recovery. Patients can expect high-quality, customized assistance at this center committed to promoting sustained sobriety and well-being.

Crossroads of Harriman

Crossroads of Harriman, situated in Harriman, TN, stands as a premier outpatient facility dedicated to aiding individuals in their recovery from substance use challenges. Their services encompass medication-assisted treatment options including methadone, buprenorphine, and naltrexone, alongside traditional outpatient counseling and remote therapy sessions via telemedicine. The center places a significant emphasis on supporting pregnant and postpartum women, serving adults and young adults across all gender identities. Crossroads of Harriman is committed to delivering personalized, high-quality care within a nurturing atmosphere conducive to healing. For those in search of thorough addiction treatment and specialized care, this establishment offers a path to recovery characterized by empathy and proven effectiveness.

Crossroads Treatment Centers

Crossroads Treatment Centers located in Greensboro, NC, provides outpatient detox and treatment services for both adults and young adults struggling with substance use. This facility emphasizes relapse prevention, counseling for substance use disorders, and offers teletherapy options. Specifically aiming to assist pregnant and postpartum women, it delivers customized treatment for all clients, regardless of gender. The program features outpatient options for methadone, buprenorphine, or naltrexone, allowing for a well-rounded strategy for recovery. Crossroads Treatment Centers in Greensboro is committed to delivering high-quality care and support for those looking to overcome addiction.

Crossroads Treatment Centers

Crossroads Treatment Centers in Asheville, NC provides comprehensive outpatient care for adults and young adults grappling with substance use. Their services encompass detoxification and ongoing treatment, with a strong emphasis on preventing relapse through specialized counseling and telehealth options. The center is dedicated to personalized approaches, offering distinct programs for pregnant and postpartum women. Clients can receive outpatient medication-assisted treatment, including methadone, buprenorphine, or naltrexone, within a supportive setting. Crossroads Treatment Centers serves both men and women looking for in-depth addiction recovery solutions in the Asheville area.

Crossroads Treatment Centers

Crossroads Treatment Centers in Ashland, KY, delivers accessible outpatient care for substance use disorders. Their programs emphasize relapse prevention and include counseling, along with medication-assisted treatment options like methadone, buprenorphine, or naltrexone. This center is committed to high-quality support for adults and young adults, featuring a dedicated program for expectant and new mothers. Recognizing the importance of convenience, Crossroads also utilizes telehealth services. Catering to all genders, Crossroads Treatment Centers offers a full spectrum of recovery support.

Crossroads Turning Points Inc

Crossroads Turning Points Inc. in Alamosa, CO, delivers extensive addiction recovery programs for adults and older individuals. They offer detox services, substance use disorder therapy, and tailored support for adults dealing with co-occurring substance use and severe mental health conditions, along with children experiencing emotional difficulties. Services include intensive outpatient and outpatient treatment, as well as medication-assisted treatment options like methadone, buprenorphine, or naltrexone. The center employs therapeutic methods such as 12-step facilitation, anger management, and brief intervention to provide personalized recovery plans. Dedicated programs are provided for teenagers, adult men, and adult women, serving a broad spectrum of individuals. Crossroads Turning Points Inc. is recognized for its commitment to high-quality care and customized treatment paths, making it a significant resource for individuals pursuing successful addiction recovery.

Crossroads Treatment Centers

Crossroads Treatment Centers in Seneca, SC, provides outpatient care for adults and young adults dealing with substance use and detoxification. They focus on preventing relapse, offering counseling for addiction, and utilizing telemedicine for therapy. The center offers specialized attention to pregnant and postpartum women, alongside individualized treatment for all genders. Crossroads Treatment Centers is recognized for its complete method in addiction recovery, delivering excellent support and care. For those needing specialized outpatient help with substance use disorders, this location offers many successful treatment strategies within a supportive setting.

Crossroads Treatment Centers

Crossroads Treatment Centers in Memphis, TN, delivers comprehensive outpatient care for substance use disorders, utilizing medication-assisted treatments such as methadone, buprenorphine, and naltrexone. They equip clients with relapse prevention techniques, offer individual and group counseling for addiction, and provide telehealth options for greater accessibility. This center is particularly dedicated to serving pregnant and postpartum women, while also extending support to adult and young adult individuals across all genders. Crossroads Treatment Centers in Memphis is committed to delivering personalized treatment plans within a nurturing atmosphere, positioning it as a premier destination for those pursuing successful and empathetic recovery from addiction.

Crossroads Turning Points Inc

Crossroads Turning Points Inc, located in Pueblo, CO, delivers a complete spectrum of addiction recovery assistance. This establishment provides medically supervised withdrawal, comprehensive substance misuse care, and dedicated support for individuals facing both addiction and significant mental health conditions in adults, or emotional challenges in youth. Their therapeutic offerings encompass intensive outpatient, extended residential stays, and regular outpatient services. The center employs proven therapeutic modalities including strategies for managing anger, prompt intervention techniques, and cognitive behavioral therapy. Catering to specific age groups and needs, including adolescents, adult males and females, and all adults and older adults regardless of gender, Crossroads Turning Points Inc is committed to delivering personalized treatment and encouragement to everyone they serve.

Crouse Health Hospital Inc

Crouse Health Hospital Inc in Syracuse, NY offers robust inpatient substance use disorder care for adults, encompassing young adults, men, and women. Employing proven methods like CBT, motivational interviewing, and relapse prevention, their programs are customized for each patient's unique journey. The center emphasizes gender-specific support within its hospital-based recovery setting, providing a nurturing space for those pursuing lasting sobriety.

Crossroads Turning Points Inc

Crossroads Turning Points Inc in Lamar, CO, specializes in treating substance use disorders and co-occurring mental health issues for both adults and children. The center offers various treatment programs, including intensive outpatient care, outpatient services, and options for methadone, buprenorphine, or naltrexone. By emphasizing methods such as 12-step programs, anger management, and brief interventions, the facility serves a diverse population that includes adolescents, adult men, and women. Catering to individuals across different gender identities, this center provides personalized care designed to address specific needs. The high standard of care and unique services available at this facility make it an essential option for those in need of thorough addiction rehabilitation and mental health assistance.

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Crossroads to Recovery, located in Brooklyn, NY, provides comprehensive outpatient and intensive outpatient treatment for substance use issues, targeting both adults and young adults. The center is particularly adept at addressing co-occurring substance use and serious mental health disorders in adults, as well as significant emotional challenges in children. Emphasizing methods such as anger management, short-term interventions, and cognitive behavioral therapy, the facility delivers personalized treatment plans designed for each individual. Additionally, distinct programs are available for individuals who have faced intimate partner violence, domestic violence, and those involved in the criminal justice system. Crossroads to Recovery welcomes clients of all genders, promoting an inclusive approach to the rehabilitation process for everyone.

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Crouse Health Hospital Inc, situated in Syracuse, NY, specializes in offering targeted substance use recovery programs designed for both adults and young adults. This center provides various outpatient services, such as outpatient day treatment, partial hospitalization, and treatments using methadone/buprenorphine or naltrexone. Their treatment methodology involves techniques like anger management, cognitive behavioral therapy, and motivational interviewing to effectively handle addiction challenges. Crouse Health Hospital Inc also features distinct programs aimed at adult men, adult women, and individuals who have faced trauma, ensuring personalized treatment plans. By emphasizing gender-specific care for both genders, the center remains dedicated to delivering high-quality and comprehensive rehabilitation support.

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Situated in Crowley, LA, the Crowley Behavioral Health Clinic provides outpatient treatment for substance use disorders in both adults and children dealing with concurrent mental health challenges. The services offered encompass anger management, brief intervention techniques, and cognitive behavioral therapy. This center serves a diverse clientele including active duty military members, teenagers, adult males, and seniors. Emphasizing quality care, the clinic features tailored treatment programs for both men and women. For those in search of thorough addiction support within a nurturing setting, the Crowley Behavioral Health Clinic is committed to guiding individuals toward sustained recovery.

Frequently Asked Questions

What is buprenorphine and how does it treat opioid addiction?
Buprenorphine is a partial opioid agonist medication approved by the FDA for treating opioid use disorder. It binds to the same receptors as heroin and fentanyl but produces a much weaker effect, reducing cravings and withdrawal symptoms without causing intense euphoria. Buprenorphine has a ceiling effect, meaning its opioid effects plateau at moderate doses, making it safer than methadone in terms of overdose risk.
What is the difference between Suboxone and Subutex?
Suboxone contains two active ingredients — buprenorphine and naloxone — while Subutex contains only buprenorphine without naloxone. The naloxone in Suboxone is included as an abuse deterrent; it remains inactive when taken sublingually as prescribed but triggers withdrawal if the medication is injected. Subutex is generally reserved for patients who cannot tolerate naloxone, such as pregnant women.
What is a Sublocade injection and how does it work?
Sublocade is a once-monthly injectable form of buprenorphine administered as a subcutaneous injection in the abdominal area. After injection, the medication forms a solid deposit under the skin that slowly releases buprenorphine over the course of a month. This eliminates daily dosing and removes the possibility of missed doses or medication diversion.
What are the common side effects of Suboxone?
Common Suboxone side effects include headache, nausea, constipation, insomnia, sweating, and mouth numbness or pain from sublingual administration. Some patients also experience dizziness, drowsiness, and blurred vision, particularly when starting treatment. Most side effects diminish within the first few weeks as the body adjusts. Patients should report difficulty breathing or signs of allergic reaction immediately.
What happens during Suboxone withdrawal?
Suboxone withdrawal occurs when a patient stops taking the medication abruptly after prolonged use, with symptoms including muscle aches, anxiety, insomnia, nausea, and irritability. A medically supervised taper is strongly recommended, typically reducing the dose by small increments over weeks or months. The risk of opioid relapse is significantly higher during unsupervised discontinuation.
How does Suboxone compare to methadone?
Suboxone and methadone are both effective for opioid use disorder but differ in key ways. Methadone is a full opioid agonist dispensed daily at licensed clinics, while Suboxone is a partial agonist that can be prescribed by qualified physicians and taken at home. Suboxone carries a lower overdose risk due to its ceiling effect and offers greater convenience, though methadone may be more appropriate for patients with severe, long-standing dependence.
How can I find a Suboxone clinic or doctor near me?
The most reliable way to find a Suboxone provider is through SAMHSA's online treatment locator at findtreatment.gov, which allows you to search by location and filter for buprenorphine providers. Many primary care offices, addiction treatment centers, and telehealth platforms now offer Suboxone prescriptions following the elimination of the federal X-waiver requirement in early 2023.
What is Zubsolv and how is it different from Suboxone?
Zubsolv is a brand-name buprenorphine and naloxone sublingual tablet that features a mint flavor and dissolves faster under the tongue than other options. Due to its higher bioavailability, Zubsolv uses different dosing strengths — a Zubsolv 5.7 mg/1.4 mg tablet is considered equivalent to a Suboxone 8 mg/2 mg dose. Patients switching between products should work closely with their prescriber for correct dose conversion.
Does Medicaid cover Suboxone treatment?
Yes — Medicaid covers buprenorphine (including Suboxone, Sublocade, Subutex, Zubsolv, and Brixadi) for opioid use disorder in all 50 states, as required by the SUPPORT Act of 2018. Medicaid is the largest single payer for MAT in the US. Coverage details vary by state — some require prior authorization or limit certain formulations. Many OBOT clinics accept Medicaid directly; telehealth Suboxone providers also bill Medicaid in most states. Bring your Medicaid card to your intake appointment.
Can I get Suboxone through telehealth?
Yes. After the MAT Act of 2023 permanently eliminated the X-waiver requirement, any licensed prescriber can prescribe Suboxone via telehealth in most states. The DEA also extended COVID-era telehealth flexibilities through at least 2025, allowing virtual Suboxone induction without a prior in-person visit. Several specialty platforms — Bicycle Health, Ophelia, Workit Health, Boulder Care — offer Medicaid-accepting telehealth Suboxone treatment. Telehealth has dramatically expanded access in rural and underserved areas with no nearby OBOT physicians.

About Buprenorphine (Suboxone)

Buprenorphine is classified as a partial opioid agonist, meaning it activates opioid receptors in the brain but to a much lesser degree than full agonists such as heroin, fentanyl, or oxycodone. This partial activation suppresses withdrawal symptoms and reduces cravings without producing dangerous respiratory depression or intense euphoria. Buprenorphine also has an unusually high binding affinity for the mu-opioid receptor, effectively blocking other opioids from attaching — providing a protective effect against relapse-related overdose.

How Buprenorphine Works

One of the defining features of buprenorphine is its ceiling effect — after a certain dose threshold, increasing the amount does not produce additional opioid effects. This dramatically reduces the risk of fatal overdose compared to methadone or illicit opioids. The ceiling effect, combined with its long duration of action (24 to 72 hours), makes buprenorphine one of the safest and most effective tools in medication-assisted treatment (MAT). Approved by the FDA in 2002, buprenorphine was a breakthrough because it could be prescribed in outpatient settings rather than requiring daily clinic visits.

Buprenorphine Brand Comparison: Suboxone, Subutex, Sublocade, Zubsolv, Brixadi

Buprenorphine is available under several FDA-approved brand names, each with distinct formulations, dosing schedules, and clinical use cases. The comparison below highlights the key differences:

BrandActive ingredientFormFrequencySettingFDA yearBest for
SuboxoneBuprenorphine + naloxoneSublingual film / tabletDailyOBOT, telehealth, retail pharmacy2002Most prescribed; naloxone deters injection misuse
SubutexBuprenorphine (alone)Sublingual tabletDailyOBOT2002Pregnancy; documented naloxone sensitivity
SublocadeBuprenorphine extended-releaseSubcutaneous injection (ATRIGEL depot)MonthlyClinic-administered2017No daily dosing; eliminates diversion risk
ZubsolvBuprenorphine + naloxoneSublingual tablet (higher bioavailability)DailyOBOT2013Faster dissolution; mint flavor; lower mg/dose
BrixadiBuprenorphine extended-releaseSubcutaneous injectionWeekly or monthlyClinic2023Newer alternative to Sublocade; weekly option for induction

All five medications are Schedule III controlled substances and equivalent in clinical efficacy at appropriate doses. The choice depends on adherence patterns, lifestyle, insurance coverage, and clinical context (e.g., pregnancy, prior injection use, daily-dosing burden). Many patients begin on sublingual Suboxone for stabilization and transition to monthly Sublocade or weekly Brixadi after sustained recovery.

Buprenorphine Side Effects

Common buprenorphine side effects include:

  • Headache and dizziness
  • Nausea and vomiting, especially during induction
  • Constipation and insomnia
  • Excessive sweating
  • Mouth numbness or oral discomfort from sublingual formulations

More serious side effects may include respiratory depression (particularly when combined with benzodiazepines or alcohol), liver problems, and allergic reactions. For most patients, side effects are mild and resolve within one to two weeks. The benefits in preventing relapse and overdose death significantly outweigh the risks.

Buprenorphine Dosage and Induction

Treatment begins with an induction phase where the patient must be in mild to moderate opioid withdrawal. Common induction doses range from 2 mg to 8 mg on the first day, with increases over the following days. Most patients stabilize on 8 mg to 24 mg per day, with 16 mg being the most commonly prescribed dose. Research suggests doses of 16 mg or higher are associated with better retention and outcomes. Dosage should always be adjusted under medical supervision.

Buprenorphine/Naloxone Combination

Many buprenorphine formulations include naloxone as an abuse deterrent. When taken sublingually as directed, naloxone has very low bioavailability and produces no clinical effect. However, if someone attempts to inject the medication, the naloxone component becomes fully active and triggers severe withdrawal. This design discourages injection misuse while having no impact on patients who take the medication correctly. The combination is the standard first-line formulation for opioid addiction treatment.

Suboxone: Sublingual Buprenorphine

Suboxone is the most recognized brand name for buprenorphine-naloxone and is most commonly dispensed as a sublingual film (Suboxone strips) that dissolves under the tongue. Suboxone has transformed opioid treatment by enabling millions of patients to receive effective pharmacotherapy in outpatient settings without the daily clinic visits required by methadone programs.

Suboxone Side Effects

Commonly reported Suboxone side effects include headache, nausea, tongue or mouth irritation, constipation, insomnia, sweating, and decreased libido. The sublingual film can cause irritation or small sores inside the mouth — rotating placement between under the tongue and against the cheek helps minimize this. Patients should not eat, drink, or smoke while the film is dissolving.

Suboxone Strips: Film vs. Tablet

Suboxone strips (sublingual film) have largely replaced the original tablet form. The film dissolves more quickly (two to four minutes), provides more consistent absorption, and is harder to divert due to individual foil packaging. Generic buprenorphine-naloxone tablets are often less expensive and may be preferred for cost reasons. Both are therapeutically equivalent when taken as prescribed.

Suboxone Treatment Programs

Comprehensive Suboxone treatment typically includes three phases:

  • Induction: Initial dosing under medical supervision, requiring the patient to be in early withdrawal
  • Stabilization: Dose adjustment until cravings and withdrawal are minimal, usually one to two months
  • Maintenance: Stable dosing for an extended period — often a year or longer — combined with counseling and behavioral therapy

Evidence consistently shows that longer treatment durations are associated with better outcomes. Most addiction medicine experts recommend a minimum of one to two years of maintenance therapy.

Find a Suboxone Clinic Near You — OBOT & Telehealth Options

Finding a Suboxone clinic has become significantly easier since the federal government eliminated the X-waiver requirement in January 2023, meaning any provider with a standard DEA license can now prescribe Suboxone. Patients can search SAMHSA's treatment locator at findtreatment.gov or use our directory to locate nearby facilities that offer buprenorphine-based treatment.

Suboxone Doctors Near Me

Beyond SAMHSA's locator, many state health departments maintain directories of addiction treatment providers. Telehealth has dramatically expanded access — several platforms now offer virtual Suboxone consultations, which is especially valuable for patients in rural areas. When selecting a provider, look for those offering comprehensive treatment including counseling, not just medication prescriptions.

Suboxone Withdrawal and Tapering

Suboxone withdrawal can include muscle aches, anxiety, insomnia, nausea, sweating, and intense opioid cravings. A gradual, medically supervised taper is recommended — typically reducing the dose by 10 to 25 percent every one to four weeks. Slower tapers over several months produce fewer symptoms and lower relapse rates. There is no medically mandated time limit for Suboxone treatment, and many patients benefit from indefinite maintenance.

Suboxone vs Methadone

Suboxone can be prescribed in office settings and taken at home, carries lower overdose risk due to its ceiling effect, and offers greater scheduling flexibility. Methadone is a full agonist that may be more effective for severe, long-standing dependence but must be dispensed at licensed clinics with daily visits. Neither is inherently superior — the best choice keeps the patient in treatment. Some patients may also benefit from naltrexone, a non-opioid alternative.

Sublocade: Monthly Buprenorphine Injection

Sublocade delivers buprenorphine as a once-monthly subcutaneous injection in the abdominal area using the ATRIGEL delivery system, which forms a solid biodegradable depot that slowly releases medication. Patients must first stabilize on sublingual buprenorphine (8 mg+ daily) for at least seven days. Treatment typically begins with two 300 mg injections, followed by maintenance on 300 mg or 100 mg. Sublocade eliminates concerns about daily adherence, missed doses, and medication diversion.

Sublocade Side Effects

The most common Sublocade side effects are injection-site reactions (pain, itching, redness, or a noticeable lump), nausea, constipation, headache, and fatigue. The injection-site lump is normal and gradually diminishes as medication is absorbed. Patients should avoid rubbing or massaging the site. Elevated liver enzymes may also occur but are usually mild and transient.

Subutex: Buprenorphine Without Naloxone

Subutex was the original brand-name buprenorphine product. While the brand has been discontinued, generic buprenorphine-only tablets remain available. Buprenorphine monotherapy is typically reserved for pregnant patients (to avoid naloxone exposure to the fetus), patients with documented naloxone sensitivity, or sometimes during the induction phase before transitioning to the combination product.

Subutex vs Suboxone

The primary difference is the absence of naloxone in Subutex. Because Subutex lacks the abuse-deterrent naloxone component, it may carry slightly higher diversion risk, and many insurance formularies prioritize the combination as the default. Current clinical guidelines favor buprenorphine-only formulations primarily for pregnancy and naloxone sensitivity.

Zubsolv: Alternative Buprenorphine Brand

Zubsolv is a buprenorphine-naloxone sublingual tablet featuring a mint flavor and faster dissolution (under two minutes). Due to enhanced bioavailability, Zubsolv uses different dose strengths — a 5.7 mg/1.4 mg tablet equals a Suboxone 8 mg/2 mg dose. Zubsolv is available in multiple strengths for flexible dosing during both induction and maintenance.

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Medically Reviewed Updated September 2026

Reviewed by licensed addiction specialists. Information reflects current clinical guidance.

Sources:SAMHSA·NIDA·CDC

Need immediate help? Call SAMHSA: 1-800-662-4357 (24/7, free)