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Medically Reviewed Content
Updated: August 2026
Sources: SAMHSA, NIDA

Depression & Addiction Treatment Centers Near You

Depression and addiction frequently co-occur, requiring integrated treatment approaches. Find dual diagnosis treatment centers addressing both mental health and substance use disorders through coordinated care and evidence-based therapies.

Found 7,770 rehab centers specializing in depression across the United States.

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Find Depression and Addiction Treatment Centers Near You

Browse dual diagnosis treatment centers below. Filter for programs treating depression and substance abuse together.

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Fairwinds Treatment Center

Fairwinds Treatment Center, located in Clearwater, FL, offers extensive long-term residential treatment specifically for detoxification, substance use challenges, and simultaneous serious mental health conditions in adults, along with emotional issues in children. They provide focused programs for active military personnel as well as adult men and women. Emphasizing 12-step support, anger management techniques, and brief interventions, this center delivers high-quality, gender-specific care for both adults and young individuals. Fairwinds Treatment Center is distinguished by its customized methods for tackling addiction and mental health issues in a nurturing and therapeutic setting.

Fall River Comprehensive Treatment Ctr

Fall River Comprehensive Treatment Ctr, located in Fall River, MA, delivers extensive outpatient services for those dealing with substance use disorders. The facility features tailored programs for adult men and women, as well as those facing dual mental health challenges. Employing techniques such as anger management, cognitive behavioral therapy, and brief interventions, it serves both adult and young adult clients of all genders. With an emphasis on high-quality care, the offerings include outpatient treatments with methadone/buprenorphine or naltrexone and consistent outpatient services. Fall River Comprehensive Treatment Ctr is committed to helping individuals navigate their recovery journey.

Family and Childrens Agency Inc

Family and Childrens Agency Inc, situated in Norwalk, CT, offers tailored support for individuals of all ages, including children and adults, grappling with substance use and co-occurring mental health challenges. Their array of services includes intensive outpatient, outpatient, and standard outpatient care. Treatment modalities employed encompass 12-step facilitation, anger management techniques, and cognitive behavioral therapy. A distinguishing feature of this center is its specialized programming designed for adult women, particularly those who have faced intimate partner violence, domestic abuse, or sexual assault. The agency is dedicated to providing comprehensive and compassionate care to women of diverse age groups—from young adults to seniors—as they embark on their journey towards recovery and well-being.

Family and Childrens Association

The Family and Childrens Association, situated in Hicksville, NY, delivers a complete spectrum of addiction recovery support. This establishment facilitates the crucial processes of detoxification and substance abuse rehabilitation through structured intensive outpatient and regular outpatient care, which encompasses outpatient detoxification services. Employing therapeutic methods like anger management, brief intervention, and cognitive behavioral therapy, this institution provides care for adolescents, adult men, and adult women. Addressing the needs of both adults and younger individuals, the center features tailored programs designed for different age demographics and genders. Committed to high standards of care and scientifically validated techniques, the Family and Childrens Association is devoted to assisting individuals in their journey towards lasting sobriety.

Family and Childrens Services Inc

Family and Childrens Services Inc, located in Fort Wayne, IN, provides outpatient treatment for adults dealing with substance use disorders alongside significant mental health challenges, as well as for children facing serious emotional issues. The treatment offerings incorporate 12-step methods, anger management strategies, and brief intervention tactics. The center caters to a variety of populations, including active military members, teenagers, and men. It emphasizes personalized care for adults and senior individuals of all gender identities, ensuring that each person's unique requirements are addressed. For individuals looking for all-encompassing assistance in a supportive setting, this center is recognized for its customized programs and dedication to delivering high-quality care.

Family Center for Recovery

Situated in Lake Worth, FL, the Family Center for Recovery delivers a wide array of services aimed at combating addiction. The center's offerings include detox, treatment for substance use disorders, transitional housing, and sober living arrangements for both adults and teens. It provides various treatment options such as intensive outpatient programs, long-term residential care, and standard outpatient services to address different needs. Additionally, specialized programs are designed for active-duty military personnel, adult male clients, and adolescents. The facility utilizes methods like 12-step facilitation, anger management, and brief interventions. Emphasizing personalized care and effective treatment strategies, the Family Center for Recovery stands as a reliable option for individuals pursuing healing and recovery.

Family Access Center

The Family Access Center in Spencer, IA, delivers extensive care for substance use disorders and dual mental health diagnoses affecting both youth and adults. They offer focused interventions for individuals impacted by trauma, domestic violence, or sexual assault, providing personalized recovery plans. Services are available through intensive outpatient, standard outpatient, and general outpatient programs. Employing proven therapeutic techniques such as cognitive behavioral therapy, the Matrix Model, and motivational interviewing, the center guarantees effective treatment. The Family Access Center welcomes adults and seniors from all walks of life, fostering a nurturing space for those on their journey to recovery and well-being.

Fam and Adolescents in Recovery

"Fam and Adolescents in Recovery, situated in Schaumburg, IL, provides targeted treatment for substance use disorders among both adults and youth facing significant mental health challenges. The center features a range of programs, including intensive outpatient, outpatient, and standard outpatient options that deliver thorough care through proven methods such as 12-step facilitation, brief intervention techniques, and cognitive behavioral therapy. Catering to all clients, the facility offers specialized services for teenagers, survivors of sexual trauma, and those who have faced various forms of trauma. Clients receive individualized support and guidance from a committed team of professionals focused on facilitating enduring recovery."

Family Counseling Center for Recovery

The Family Counseling Center for Recovery, situated in Richmond, VA, delivers focused outpatient care for individuals battling substance use disorders and co-occurring mental health conditions. Their treatment offerings encompass medication-assisted treatment utilizing methadone, buprenorphine, or naltrexone, alongside specialized programs such as anger management, cognitive behavioral therapy, and brief intervention strategies. They also provide distinct treatment paths for active duty military members, adult men, and women, thereby elevating the standard of care. Serving adults and young adults across genders, the center's all-encompassing methodology guarantees customized and impactful assistance for those pursuing sobriety and well-being.

Family Counseling Center for Recovery

The Family Counseling Center for Recovery, situated in Richmond, VA, delivers thorough outpatient care for substance misuse. This establishment focuses on addressing dual diagnoses of substance use disorders and significant mental health conditions in adults, as well as severe emotional challenges in youth. Offering customized plans for active duty service members, adult males, and females, the center features services such as 12-step program support, anger control techniques, and short-term therapeutic interventions. Catering to adults and young adults irrespective of gender, this facility emphasizes high-quality support and personalized treatment strategies aimed at fostering sustained healing.

Family ACTS Inc
Ford City, PA

Situated in Ford City, PA, Family ACTS Inc specializes in outpatient treatment for substance use issues affecting both adults and teens. The center delivers consistent outpatient services with an emphasis on anger management, short-term interventions, and cognitive behavioral therapy. Family ACTS Inc serves active military members as well as adult males and teenagers, providing services to clients of all genders. With a strong emphasis on quality care, this facility is committed to assisting individuals in their journey to overcome addiction through customized treatment plans that address the unique needs of each person. For those in search of effective substance use treatment within a nurturing setting, Family ACTS Inc is ready to assist.

Family and Childrens Services

Situated in Midland, MI, Family and Children's Services provides outpatient rehabilitation services for both adults and children dealing with substance use challenges alongside related mental health conditions. This center excels in anger management strategies, cognitive behavioral therapy, and motivational interviewing techniques. It offers customized programs for individuals who have faced issues such as intimate partner violence, trauma, or are managing both mental health and substance use disorders simultaneously. Catering to adults and seniors across all gender identities, the center is dedicated to offering exceptional care aimed at fostering enduring recovery and enhanced mental well-being.

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Situated in Fallon, NV, the Fallon Tribal Health Clinic provides outpatient services aimed at treating substance use issues, particularly focusing on individuals facing both substance use disorders and significant mental health challenges in adults, alongside emotional difficulties in children. The clinic employs proven methods such as 12-step programs, anger management techniques, and cognitive behavioral therapy. They offer consistent outpatient support to adult men and women, in addition to teenagers. By concentrating on customized programs that cater to different age groups and genders, the center guarantees a personalized and effective approach for individuals pursuing recovery and rehabilitation.

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Council Bluffs, IA

Situated in Council Bluffs, IA, the Family Access Center delivers thorough substance abuse rehabilitation and tailored support for those facing concurrent mental health issues. This center offers a range of treatment options, including intensive outpatient and outpatient programs, utilizing proven methods like cognitive behavioral therapy, the Matrix Model, and motivational interviewing. There are specialized programs available for individuals who have faced intimate partner violence, sexual trauma, or other traumatic experiences. Catering to adults and seniors of all genders, the center emphasizes quality care and personalized treatment plans to promote enduring recovery and mental health.

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Sioux City, IA

Situated in Sioux City, IA, the Family Access Center provides a full spectrum of care for individuals struggling with addiction. The center excels in addressing dual diagnoses, where substance use disorders intersect with significant mental health challenges. They offer a variety of program levels, including intensive outpatient, standard outpatient, and regular outpatient services. Employing proven therapeutic methods like cognitive behavioral therapy, the Matrix Model, and motivational interviewing, the Family Access Center designs personalized recovery plans for adult men, adult women, and survivors of intimate partner or domestic violence. Serving adults and seniors of all genders, the Family Access Center is dedicated to delivering exceptional support and treatment to foster lasting recovery.

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Family and Children's Services, located in Tulsa, OK, provides an extensive array of treatment programs for substance use and concurrent mental health issues. Their offerings encompass various levels of care, including intensive and regular outpatient services designed for both adults and young adults. The facility emphasizes techniques such as anger management, brief interventions, and cognitive behavioral therapy. They also feature specialized programs tailored for adult men, women, and those who have faced trauma. Committed to personalized care, this center aims to deliver effective support for individuals of all genders on their journey to recovery.

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Jeffersonville, IN

Family Ark, located in Jeffersonville, IN, delivers a full spectrum of care for those struggling with addiction, including accommodations for transitional living. Their offerings encompass robust outpatient programs, extended residential stays, and flexible outpatient services, all grounded in proven therapeutic techniques like anger management, cognitive behavioral therapy, and the Matrix Model. Specifically designed for adult women, individuals with trauma histories, and those facing dual diagnoses of mental health and substance use issues, Family Ark warmly welcomes adults and seniors of any gender seeking effective and nurturing support.

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The Family Behavioral Health Clinic, situated in Des Plaines, IL, provides customized treatment programs for substance use that cater to the unique needs of each individual. The facility emphasizes a continuum of care including intensive outpatient, outpatient, and standard outpatient options. It utilizes a variety of methodologies such as anger management techniques, brief interventions, and cognitive behavioral therapy. Special programs are designed for adolescents and adult men and women, and services are accessible to adults and seniors of all genders. The clinic is dedicated to providing exceptional care in a friendly atmosphere, making it a prime option for individuals looking for thorough and effective addiction recovery solutions.

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The Family Center of Thomas Jefferson Univ, situated in Philadelphia, PA, is dedicated to assisting adult women who have faced intimate partner violence, domestic abuse, or sexual trauma by providing specialized substance use disorder treatment. They offer robust programs including intensive outpatient care, general outpatient services, and medication-assisted treatment with methadone, buprenorphine, or naltrexone. The center delivers holistic support, integrating approaches such as 12-step facilitation, anger management training, and brief intervention strategies. Serving adults, seniors, and young adults, the Family Center of Thomas Jefferson Univ is committed to delivering empathetic and effective care to support clients in achieving lasting recovery.

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Situated in Orange, NJ, Family Connections Inc provides a wide array of treatment options for individuals grappling with substance use issues, catering to both adults and children. The center offers various levels of care including intensive outpatient, outpatient, and regular outpatient programs. It focuses on therapies such as anger management, cognitive behavioral therapy, and motivational interviewing, specifically designed for adults and teens facing dual diagnoses of substance use and significant mental health challenges. Family Connections Inc is dedicated to individualized treatment and evidence-based practices, providing tailored programs for adult men, adult women, and adolescents. The facility is committed to delivering compassionate and effective rehabilitation support to all clients, regardless of gender.

Depression & Substance Use Disorder: Key Facts

Classification

Major Depressive Disorder + Substance Use Disorder (Dual Diagnosis)

Co-occurrence

~1 in 3 people with depression also have SUD (NIDA)

Prevalence

21 million adults with major depressive episode/year (NIMH)

Self-medication

Depression is the #1 reason for substance self-medication

Treatment approach

Integrated dual diagnosis (treat both simultaneously)

Key therapies

CBT, DBT, medication management, group therapy

Medications

SSRIs (non-addictive), SNRIs — safe during addiction treatment

Prognosis

Significantly better outcomes with integrated treatment vs sequential

If you or someone you know is experiencing suicidal thoughts, call 988 (Suicide & Crisis Lifeline) or text 988 immediately. Help is available 24/7.

Depression and Addiction: The Dual Diagnosis Connection

How depression and addiction feed each other

Depression and substance use disorder share a deeply intertwined relationship. Depression causes persistent feelings of emptiness, hopelessness, and emotional pain that drive many people toward alcohol or drugs as a form of self-medication. Substances may provide temporary relief, but they alter brain chemistry in ways that worsen depressive symptoms over time — creating a destructive cycle that accelerates both conditions.

The self-medication cycle

The self-medication cycle is the most common pathway from depression to addiction. A person experiencing persistent sadness, fatigue, or emotional numbness turns to alcohol, opioids, or stimulants to feel better temporarily. As tolerance builds, they need more of the substance to achieve the same relief. Meanwhile, the substance disrupts serotonin and dopamine regulation in the brain, deepening the depression. When the substance wears off, the depression returns worse than before — driving further substance use.

Why treating one without the other fails

Treating addiction without addressing underlying depression leaves the root cause intact. The person achieves sobriety but continues suffering from untreated depression, making relapse nearly inevitable as they seek relief. Conversely, treating depression without addressing active substance use is ineffective because ongoing drug or alcohol use undermines the neurochemical changes that antidepressants and therapy work to achieve. This is why dual diagnosis treatment — addressing both conditions simultaneously — produces significantly better outcomes than treating either condition alone.

Signs of Co-Occurring Depression and Substance Abuse

Recognizing co-occurring depression and substance abuse can be challenging because symptoms overlap. Watch for these warning signs:

Emotional and behavioral signs

  • Persistent sadness combined with increased substance use
  • Withdrawal from friends, family, and activities once enjoyed
  • Using drugs or alcohol specifically to cope with emptiness or hopelessness
  • Feelings of worthlessness or excessive guilt alongside substance use
  • Loss of motivation or interest in recovery efforts

Physical signs

  • Significant changes in sleep patterns — insomnia or oversleeping
  • Appetite and weight changes (loss or gain)
  • Chronic fatigue even with adequate rest
  • Increased substance tolerance requiring higher doses
  • Neglect of personal hygiene and self-care

How Dual Diagnosis Treatment Works

Integrated approach

Dual diagnosis treatment treats depression and addiction as interconnected conditions rather than separate problems. Instead of completing addiction treatment first and then addressing depression (the sequential approach that often fails), integrated programs work on both simultaneously. This means therapy sessions address how depressive thoughts drive substance use, while psychiatric care stabilizes mood to support sobriety.

Psychiatric evaluation during early sobriety

Accurate diagnosis of depression requires evaluation during a period of sobriety, because many substances can mimic or mask depressive symptoms. Alcohol is a depressant that causes sadness and lethargy. Stimulant withdrawal causes profound depression. A psychiatrist experienced in dual diagnosis will conduct thorough assessments during early sobriety to distinguish substance-induced mood changes from underlying major depressive disorder, ensuring the right treatment plan.

Coordinated care teams

Effective dual diagnosis programs use coordinated care teams where psychiatrists, addiction counselors, therapists, and medical staff communicate about each patient's progress. The psychiatrist managing antidepressant medication works closely with the addiction counselor guiding recovery, so treatment decisions account for both conditions. This prevents the common problem of one provider unknowingly undermining another's treatment plan.

Medication management alongside addiction treatment

One of the most important aspects of dual diagnosis care is safe medication management. Antidepressants like SSRIs and SNRIs are non-addictive and can be prescribed safely during addiction treatment. A psychiatrist monitors medication effectiveness, adjusts dosages, and watches for interactions — all while the person is actively working on recovery from substance use disorder.

Evidence-Based Therapies for Depression in Recovery

Cognitive Behavioral Therapy (CBT)

Cognitive Behavioral Therapy (CBT) is the gold standard for treating co-occurring depression and addiction. CBT helps identify negative thought patterns that drive both depressive episodes and substance use — such as "nothing will ever get better" or "I can't cope without drinking." Patients learn to challenge these distortions and replace them with realistic, constructive thinking. Research consistently shows CBT reduces both depressive symptoms and substance use relapse rates.

Dialectical Behavior Therapy (DBT)

Dialectical Behavior Therapy (DBT) is particularly effective for people with severe depression, emotional dysregulation, or self-harm behaviors alongside addiction. DBT teaches four core skill sets: mindfulness, distress tolerance, emotion regulation, and interpersonal effectiveness. These skills directly address the emotional pain that drives self-medication and provide healthier alternatives to substance use.

Group therapy

Group therapy combats the isolation that is central to both depression and addiction. Hearing others share similar struggles reduces shame and hopelessness. Dual diagnosis groups specifically address how depression and substance use interact, offering peer support from people who understand both conditions. Group settings also build social skills and accountability that support long-term recovery.

Medication management

Antidepressant medications are a critical component of treatment for many people with co-occurring depression and addiction. SSRIs (selective serotonin reuptake inhibitors) like sertraline and fluoxetine are first-line treatments because they are effective, well-tolerated, and — importantly — non-addictive. They carry no abuse potential and do not produce euphoria, making them safe to prescribe during addiction recovery. SNRIs like venlafaxine and duloxetine are also effective alternatives.

Levels of Care for Depression and Addiction

When residential treatment is needed

Residential treatment is recommended when depression is severe — particularly when suicidal ideation is present, when the person has made previous suicide attempts, or when outpatient treatment has failed. Residential programs provide 24/7 psychiatric monitoring, immediate medication adjustments, and a safe environment removed from triggers. People with severe addiction alongside major depression often need this level of structured support to stabilize both conditions.

Intensive Outpatient Programs (IOP)

Intensive Outpatient Programs provide 9–20 hours of structured therapy per week while allowing patients to live at home. IOP is appropriate for moderate depression with addiction, for people stepping down from residential care, or when the person has a stable living environment and support system. Dual diagnosis IOP programs include both addiction counseling and psychiatric services.

Outpatient care with medication management

Standard outpatient treatment works well for mild to moderate depression with substance use disorder, especially when combined with antidepressant medication. This typically involves weekly therapy sessions, regular psychiatric check-ins for medication management, and support group participation. Outpatient care allows people to maintain work, family, and daily responsibilities while receiving treatment.

Choosing the right level of care

The appropriate level of care depends on several factors: severity of depression (mild vs. severe with suicidal thoughts), severity of addiction, previous treatment attempts and outcomes, strength of social support, co-occurring medical conditions, and safety concerns. A professional assessment by a dual diagnosis specialist can determine the best starting point. Many people move through multiple levels of care as they progress in recovery.

Antidepressant Medications in Recovery

SSRIs: the first-line treatment

Selective serotonin reuptake inhibitors (SSRIs) such as sertraline (Zoloft), fluoxetine (Prozac), and escitalopram (Lexapro) are the most commonly prescribed antidepressants for people in addiction recovery. They work by increasing serotonin availability in the brain, gradually improving mood, sleep, and motivation over 4–6 weeks. SSRIs are not addictive, do not produce a high, and have no abuse potential — making them fundamentally different from the substances being treated.

SNRIs and bupropion

Serotonin-norepinephrine reuptake inhibitors (SNRIs) like venlafaxine (Effexor) and duloxetine (Cymbalta) target both serotonin and norepinephrine, which can be helpful for depression with prominent fatigue or chronic pain. Bupropion (Wellbutrin) is another option that acts on dopamine and norepinephrine — it can help with depression, low energy, and is also used to support smoking cessation. None of these medications carry addiction risk.

Addressing the stigma around psychiatric medication

Many people in recovery resist antidepressants because they feel taking any medication contradicts sobriety. This misconception is dangerous. Antidepressants are not mood-altering substances in the way drugs of abuse are — they restore normal brain chemistry rather than creating artificial highs. Untreated depression is one of the strongest predictors of addiction relapse. Taking prescribed, non-addictive medication to manage a medical condition is not a failure of recovery — it supports it.

Why stopping psychiatric meds leads to relapse

A common and harmful pattern occurs when people in recovery stop their antidepressants because they feel better, believe they no longer need them, or face pressure from others to be "medication-free." When depression returns — often within weeks — the emotional pain drives them back to substances. Antidepressant treatment for co-occurring depression should be maintained for at least 12 months after stabilization, and many people benefit from long-term maintenance. Any changes to psychiatric medication should be made gradually under medical supervision.

Frequently Asked Questions About Depression and Addiction

What is dual diagnosis treatment for depression and addiction?

Dual diagnosis treatment addresses both depression and substance use disorders simultaneously through integrated care. This approach recognizes that mental health and addiction affect each other and must be treated together for lasting recovery. Treatment includes psychiatric care, medication management, therapy (CBT, DBT), and specialized counseling that addresses both conditions comprehensively.

Can depression cause substance abuse?

Yes, depression significantly increases the risk of substance abuse. Many people self-medicate depression symptoms with alcohol or drugs, seeking temporary relief from emotional pain, low energy, or insomnia. However, substance use worsens depression long-term by disrupting serotonin and dopamine regulation, creating a vicious cycle. Proper treatment addresses root causes of depression while providing healthier coping strategies than substances.

Will antidepressants interfere with addiction treatment?

No, appropriate antidepressant medication actively supports recovery. Quality dual diagnosis programs work with psychiatrists to find effective antidepressant treatment while addressing addiction. Medications like SSRIs and SNRIs are non-addictive and help stabilize mood, making it easier to engage in therapy and maintain sobriety. Never stop psychiatric medications without medical guidance.

How do I find a treatment center for depression and addiction?

Look for centers explicitly offering dual diagnosis or co-occurring disorder treatment. Verify they have licensed mental health professionals, psychiatric services, medication management capabilities, and experience treating both conditions together. Use our directory to filter for dual diagnosis programs, read reviews, and verify accreditation. Contact admissions teams to discuss your specific needs.

Is residential treatment necessary for depression and addiction?

Not always. Treatment level depends on severity of both conditions, previous treatment attempts, safety concerns, and support system. Some people do well with intensive outpatient care plus medication management. Residential treatment provides 24/7 support for severe depression, suicide risk, or when outpatient treatment hasn't succeeded. A professional assessment determines the most appropriate level of care.

Can addiction cause depression or does depression cause addiction?

The relationship is bidirectional — it works both ways. Depression can lead to substance abuse through self-medication, as people use drugs or alcohol to escape emotional pain. At the same time, chronic substance use alters brain chemistry in ways that cause or worsen depression — alcohol is a central nervous system depressant, stimulant withdrawal causes profound depression, and opioid use disrupts the brain's natural mood regulation. In many cases, both conditions develop and reinforce each other simultaneously, which is why integrated dual diagnosis treatment is essential for lasting recovery.

Will I need antidepressants forever?

Not necessarily. Many people take antidepressants for 12–24 months after their mood stabilizes, then gradually taper off under medical supervision. However, some people with recurrent major depression (three or more episodes) benefit from long-term maintenance medication. The decision depends on depression severity, number of past episodes, family history, and individual response to treatment. What is critical is never stopping antidepressants abruptly — doing so can cause withdrawal symptoms and trigger relapse in both depression and addiction. Always work with your prescribing psychiatrist to make any medication changes.

Medical Review and Sources

Medically Reviewed Updated April 10, 2026

Reviewed by licensed addiction specialists. Information reflects current clinical guidance.

Sources:SAMHSA·NIDA·CDC

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