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Medically Reviewed Content
Updated: August 2026
Sources: SAMHSA, NIDA

Depression & Addiction Treatment Centers Near You

Depression and addiction frequently co-occur, requiring integrated treatment approaches. Find dual diagnosis treatment centers addressing both mental health and substance use disorders through coordinated care and evidence-based therapies.

Found 7,770 rehab centers specializing in depression across the United States.

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Find Depression and Addiction Treatment Centers Near You

Browse dual diagnosis treatment centers below. Filter for programs treating depression and substance abuse together.

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Family Matters Counseling Services LLC

Family Matters Counseling Services LLC in North Platte, NE, provides outpatient support for individuals struggling with substance abuse and dual diagnoses of significant mental health conditions. This establishment focuses on assisting adults experiencing severe emotional challenges through consistent outpatient services. Employing methods such as anger management, cognitive behavioral therapy, and contingency management, the center customizes care plans to suit each person's unique requirements. Offering distinct programs for young people, adult males, and females, this facility caters to a broad range of clients. Both adults and older adults of any gender can receive high-quality treatment at this location, establishing it as a crucial provider of effective and individualized recovery options.

Family First Community Servs LLC

Family First Community Servs LLC, situated in Charlotte, NC, presents a wide array of substance use treatment services designed for both adults and children/adolescents dealing with co-occurring severe mental health challenges. The center features intensive outpatient, outpatient, and standard outpatient treatment choices, employing evidence-driven methods such as anger management, brief intervention strategies, and cognitive behavioral therapy. With distinct programs available for adolescents, adult men, and adult women, the facility addresses the unique needs of various age groups and genders. Clients can anticipate personalized care provided in a nurturing and supportive atmosphere.

Family Healthcare Center at SSTAR

Family Healthcare Center at SSTAR, located in Fall River, MA, provides an array of specialized programs to address substance use and concurrent mental health issues. Their offerings include outpatient and intensive outpatient services that employ evidence-based methods like cognitive behavioral therapy, motivational interviewing, and contingency management. The center caters to diverse populations, creating customized programs for active duty military personnel, teenagers, and adult males, while also ensuring individualized support for adults and seniors of every gender. Their commitment to high-quality care and a wide variety of treatment options positions this facility as an essential resource for individuals in need of extensive rehabilitation services in the Fall River community.

Family Counseling Center for Recovery

Nestled in Fredericksburg, VA, the Family Counseling Center for Recovery delivers extensive outpatient support for individuals pursuing freedom from addiction. This establishment offers detox services, addiction treatment, and tailored support for individuals facing dual mental health diagnoses. Their therapeutic methods encompass 12-step integration, emotional regulation skills, and concise intervention strategies. Distinctive offerings are available for adult females, those who have experienced trauma, and individuals with co-occurring conditions. Serving adult and young adult men and women, the center is dedicated to providing high-standard assistance and encouragement during the recovery journey.

Family Health Centers of San Diego Inc

Family Health Centers of San Diego Inc., situated in San Diego, CA, delivers a full spectrum of care for substance use disorders. Services include intensive outpatient, standard outpatient, and regular outpatient treatment options for adults and adolescents. This facility specializes in cognitive behavioral therapy, anger management, and brief intervention techniques, serving individuals with co-occurring mental health conditions. Tailored programs are offered to clients with histories of trauma and those in the LGBTQ community. The center provides dedicated support for both male and female patients addressing substance use and mental health concerns.

Family Health Centers of San Diego Inc

Family Health Centers of San Diego Inc, situated in Imperial Beach, CA, provides extensive support for individuals struggling with substance use disorders. This center specializes in addressing co-occurring mental health conditions alongside substance dependence for both adults and young adults. Their treatment options include structured outpatient and intensive outpatient programs, with provisions for methadone and buprenorphine services. Employing proven therapeutic methods such as cognitive behavioral therapy and contingency management, Family Health Centers of San Diego Inc is equipped to support active duty military members, adult men, and women. They are committed to delivering tailored care, recognizing the importance of gender-specific and age-appropriate interventions to foster successful recovery.

Family Counseling Service of

The Family Counseling Service located in Reno, NV, provides outpatient care for adults dealing with substance use and simultaneous mental health issues. The center employs various therapeutic techniques, including 12-step programs, cognitive behavioral therapy, and short-term interventions. Its services are designed for adult men and women, as well as those who have faced intimate partner violence and domestic abuse survivors. Customized treatment plans are available for both adults and young adults, promoting comprehensive support for a wide array of individuals. Committed to quality treatment and evidence-driven methods, this center aims to assist individuals in attaining sustainable recovery and enhanced mental health.

Family Guidance Center
Saint Joseph, MO

Located in Saint Joseph, MO, the Family Guidance Center provides an extensive array of services for addiction rehabilitation. This center includes detox programs, treatment for substance use disorders, and specialized support for those facing both addiction and significant mental health challenges. Treatment options offered encompass intensive outpatient programs, general outpatient services, and partial hospitalization or outpatient day treatment. Featuring personalized methods like 12-step support, anger management, and brief intervention strategies, the facility serves adult men, women, and individuals dealing with co-occurring mental health and substance use issues. The Family Guidance Center is dedicated to offering excellent care in a nurturing setting for adults and young adults of all genders.

Family Intervention Center Inc

Family Intervention Center Inc, located in Waterbury, CT, specializes in outpatient treatment for substance use issues as well as care for individuals facing both substance use and serious mental health challenges, applicable to both adults and children with significant emotional difficulties. Their offerings encompass anger management, brief interventions, and cognitive behavioral therapy. The center also caters to active military members, teenagers, and adult males, tailoring its services to meet diverse needs. With an emphasis on providing quality recovery support to adults and seniors of all genders, this facility is dedicated to the betterment of all seeking assistance on their recovery journey.

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Family Counseling Center Inc, located in Hayti, MO, provides a wide range of addiction recovery services, including detox and treatment for substance use disorders. The center features inpatient detox and treatment options offering round-the-clock care for adults and young adults. Employing methods such as 12-step programming, anger management, and short-term interventions, the facility serves both male and female clients. Tailored programs are also in place for adult men, women, and those who have faced intimate partner or domestic violence. This center is dedicated to delivering effective care and assistance to individuals on their path to recovery from addiction.

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Situated in Greenville, MO, Family Counseling Center Inc delivers extensive treatment for substance use disorders alongside specialized support for adults facing co-occurring substance use and severe mental health issues, as well as for children dealing with significant emotional challenges. The center offers outpatient services that incorporate treatments such as methadone/buprenorphine and naltrexone. Additionally, it features various services including anger management, cognitive behavioral therapy, and short-term interventions. The facility also provides customized programs for active-duty service members, adolescents, and adult males. Catering to both adults and youths and serving clients of all genders, this center is dedicated to delivering high-quality care through personalized treatment and supportive measures.

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Situated in Mountain Grove, MO, Family Counseling Center Inc provides extensive outpatient treatment for substance use issues in both adults and young adults. This center excels in addressing co-occurring substance use disorders along with significant mental health challenges in adults or emotional issues in children. The treatment program incorporates proven methods like 12-step facilitation, anger management strategies, and concise interventions. Moreover, the facility offers tailored support for individuals who have faced sexual abuse or trauma. Emphasizing high-quality care and personalized treatment plans, Family Counseling Center Inc serves both male and female individuals on their journey to recovery and overall wellness.

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Family Counseling Center Inc. in Ava, MO, provides extensive outpatient services for individuals of all ages struggling with substance use. The center excels in addressing dual diagnoses, integrating care for co-occurring mental health conditions alongside addiction. Their therapeutic offerings encompass structured approaches like 12-step facilitation, anger management, and brief intervention strategies, all designed to meet unique client requirements. Furthermore, Family Counseling Center Inc. offers dedicated support for individuals with histories of trauma and those involved in the legal system. They are committed to delivering high-quality rehabilitation, welcoming both male and female patients.

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Family Guidance Centers Inc located in Springfield, IL, delivers a wide range of treatment options for substance use disorders, including long-term residential programs, outpatient services, and specialized outpatient programs using methadone, buprenorphine, or naltrexone. Emphasizing methods such as 12-step support, cognitive behavioral therapy, and motivational interviewing, the center serves both adult men and women, as well as individuals facing dual diagnoses of mental and substance use disorders. With a strong focus on care for adults and young adults, Family Guidance Centers Inc features gender-specific treatments designed for both men and women. The center is committed to offering exceptional support and resources for those on their path to recovery and a clean lifestyle.

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Situated in Morehead, KY, Family Healing Center Inc delivers an array of extensive rehabilitation services. The facility focuses on treating substance abuse and co-occurring mental health disorders for both adults and children. Offered treatment options encompass intensive outpatient programs, as well as regular and outpatient services. Emphasizing anger management, short-term interventions, and cognitive behavioral therapy, the center caters to the unique needs of active duty military personnel, adolescents, adult males, and individuals of diverse gender identities. By prioritizing adults and seniors, this center guarantees high-quality care through evidence-based methods and specialized programs, making it an essential resource for those in search of effective and individualized rehabilitation assistance.

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Hyattsville, MD

Situated in Hyattsville, MD, the Family Health Center specializes in treating substance use disorders and co-occurring mental health conditions in both adults and children. The center offers various levels of care, including intensive outpatient, outpatient, and standard outpatient programs, ensuring that treatment is personalized and effective. Approaches such as 12-step facilitation, anger management, and brief interventions are utilized to support recovery. Additionally, there are targeted programs for active duty service members, teenagers, and adult males to address their unique challenges. Catering to individuals of all genders, the Family Health Center fosters a holistic and supportive atmosphere for those on their path to recovery. Clients can anticipate high-quality care and individualized treatment strategies.

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The Family Institute of Northern Utah, situated in Logan, UT, provides comprehensive outpatient services for individuals struggling with substance use. They specialize in treating co-occurring disorders, addressing both substance use issues and serious mental health conditions in adults, or severe emotional disturbances in children. Their regular outpatient program emphasizes crucial areas such as anger management, relapse prevention strategies, and dedicated counseling for substance use disorders. The institute also offers distinctive programs specifically designed for adult men and women, as well as those who have faced intimate partner or domestic violence. Catering to adults and seniors across all genders, the center is committed to delivering high-quality, individualized care, fostering an environment conducive to healing and sustained recovery.

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Situated in Galion, OH, Family Life Counseling provides an extensive array of rehabilitation services for those facing challenges related to substance abuse and concurrent mental health conditions. The center offers various treatment options, including intensive outpatient, outpatient, and standard outpatient programs, employing techniques like anger management, brief intervention, and cognitive behavioral therapy. Specialized programs are available for active duty service members, teenagers, and adult males. By prioritizing the needs of adults and seniors across all genders, this facility guarantees personalized care and support, positioning itself as an essential option for individuals seeking effective addiction recovery solutions in the region.

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Family Life Counseling, located in Millersburg, OH, provides outpatient substance abuse rehabilitation for adults and youngsters dealing with concurrent severe mental health conditions. Employing methodologies such as anger management and cognitive behavioral therapy, this establishment delivers ongoing outpatient services focused on high-quality care. Specialized services are available for active duty military personnel, teenagers, and adult men. Catering to a diverse clientele including adults and older adults of any gender, the center prioritizes personalized treatment strategies crafted to meet individual client requirements, thereby guaranteeing a thorough and impactful recovery journey.

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Family Medical Centers in Ironton, OH, delivers extensive outpatient care tailored for adults facing substance use disorders and concurrent serious mental health issues, along with support for children's emotional challenges. This center features targeted programs for both adult males and females, as well as those who have undergone trauma. Treatment strategies encompass anger management, short-term interventions, and cognitive behavioral therapy. The services provided are designed for adults and young adults, ensuring distinct programs for each gender. With an emphasis on high-quality treatment and multiple outpatient options, including methadone/buprenorphine or naltrexone therapies, this center is committed to guiding individuals on their recovery journey.

Depression & Substance Use Disorder: Key Facts

Classification

Major Depressive Disorder + Substance Use Disorder (Dual Diagnosis)

Co-occurrence

~1 in 3 people with depression also have SUD (NIDA)

Prevalence

21 million adults with major depressive episode/year (NIMH)

Self-medication

Depression is the #1 reason for substance self-medication

Treatment approach

Integrated dual diagnosis (treat both simultaneously)

Key therapies

CBT, DBT, medication management, group therapy

Medications

SSRIs (non-addictive), SNRIs — safe during addiction treatment

Prognosis

Significantly better outcomes with integrated treatment vs sequential

If you or someone you know is experiencing suicidal thoughts, call 988 (Suicide & Crisis Lifeline) or text 988 immediately. Help is available 24/7.

Depression and Addiction: The Dual Diagnosis Connection

How depression and addiction feed each other

Depression and substance use disorder share a deeply intertwined relationship. Depression causes persistent feelings of emptiness, hopelessness, and emotional pain that drive many people toward alcohol or drugs as a form of self-medication. Substances may provide temporary relief, but they alter brain chemistry in ways that worsen depressive symptoms over time — creating a destructive cycle that accelerates both conditions.

The self-medication cycle

The self-medication cycle is the most common pathway from depression to addiction. A person experiencing persistent sadness, fatigue, or emotional numbness turns to alcohol, opioids, or stimulants to feel better temporarily. As tolerance builds, they need more of the substance to achieve the same relief. Meanwhile, the substance disrupts serotonin and dopamine regulation in the brain, deepening the depression. When the substance wears off, the depression returns worse than before — driving further substance use.

Why treating one without the other fails

Treating addiction without addressing underlying depression leaves the root cause intact. The person achieves sobriety but continues suffering from untreated depression, making relapse nearly inevitable as they seek relief. Conversely, treating depression without addressing active substance use is ineffective because ongoing drug or alcohol use undermines the neurochemical changes that antidepressants and therapy work to achieve. This is why dual diagnosis treatment — addressing both conditions simultaneously — produces significantly better outcomes than treating either condition alone.

Signs of Co-Occurring Depression and Substance Abuse

Recognizing co-occurring depression and substance abuse can be challenging because symptoms overlap. Watch for these warning signs:

Emotional and behavioral signs

  • Persistent sadness combined with increased substance use
  • Withdrawal from friends, family, and activities once enjoyed
  • Using drugs or alcohol specifically to cope with emptiness or hopelessness
  • Feelings of worthlessness or excessive guilt alongside substance use
  • Loss of motivation or interest in recovery efforts

Physical signs

  • Significant changes in sleep patterns — insomnia or oversleeping
  • Appetite and weight changes (loss or gain)
  • Chronic fatigue even with adequate rest
  • Increased substance tolerance requiring higher doses
  • Neglect of personal hygiene and self-care

How Dual Diagnosis Treatment Works

Integrated approach

Dual diagnosis treatment treats depression and addiction as interconnected conditions rather than separate problems. Instead of completing addiction treatment first and then addressing depression (the sequential approach that often fails), integrated programs work on both simultaneously. This means therapy sessions address how depressive thoughts drive substance use, while psychiatric care stabilizes mood to support sobriety.

Psychiatric evaluation during early sobriety

Accurate diagnosis of depression requires evaluation during a period of sobriety, because many substances can mimic or mask depressive symptoms. Alcohol is a depressant that causes sadness and lethargy. Stimulant withdrawal causes profound depression. A psychiatrist experienced in dual diagnosis will conduct thorough assessments during early sobriety to distinguish substance-induced mood changes from underlying major depressive disorder, ensuring the right treatment plan.

Coordinated care teams

Effective dual diagnosis programs use coordinated care teams where psychiatrists, addiction counselors, therapists, and medical staff communicate about each patient's progress. The psychiatrist managing antidepressant medication works closely with the addiction counselor guiding recovery, so treatment decisions account for both conditions. This prevents the common problem of one provider unknowingly undermining another's treatment plan.

Medication management alongside addiction treatment

One of the most important aspects of dual diagnosis care is safe medication management. Antidepressants like SSRIs and SNRIs are non-addictive and can be prescribed safely during addiction treatment. A psychiatrist monitors medication effectiveness, adjusts dosages, and watches for interactions — all while the person is actively working on recovery from substance use disorder.

Evidence-Based Therapies for Depression in Recovery

Cognitive Behavioral Therapy (CBT)

Cognitive Behavioral Therapy (CBT) is the gold standard for treating co-occurring depression and addiction. CBT helps identify negative thought patterns that drive both depressive episodes and substance use — such as "nothing will ever get better" or "I can't cope without drinking." Patients learn to challenge these distortions and replace them with realistic, constructive thinking. Research consistently shows CBT reduces both depressive symptoms and substance use relapse rates.

Dialectical Behavior Therapy (DBT)

Dialectical Behavior Therapy (DBT) is particularly effective for people with severe depression, emotional dysregulation, or self-harm behaviors alongside addiction. DBT teaches four core skill sets: mindfulness, distress tolerance, emotion regulation, and interpersonal effectiveness. These skills directly address the emotional pain that drives self-medication and provide healthier alternatives to substance use.

Group therapy

Group therapy combats the isolation that is central to both depression and addiction. Hearing others share similar struggles reduces shame and hopelessness. Dual diagnosis groups specifically address how depression and substance use interact, offering peer support from people who understand both conditions. Group settings also build social skills and accountability that support long-term recovery.

Medication management

Antidepressant medications are a critical component of treatment for many people with co-occurring depression and addiction. SSRIs (selective serotonin reuptake inhibitors) like sertraline and fluoxetine are first-line treatments because they are effective, well-tolerated, and — importantly — non-addictive. They carry no abuse potential and do not produce euphoria, making them safe to prescribe during addiction recovery. SNRIs like venlafaxine and duloxetine are also effective alternatives.

Levels of Care for Depression and Addiction

When residential treatment is needed

Residential treatment is recommended when depression is severe — particularly when suicidal ideation is present, when the person has made previous suicide attempts, or when outpatient treatment has failed. Residential programs provide 24/7 psychiatric monitoring, immediate medication adjustments, and a safe environment removed from triggers. People with severe addiction alongside major depression often need this level of structured support to stabilize both conditions.

Intensive Outpatient Programs (IOP)

Intensive Outpatient Programs provide 9–20 hours of structured therapy per week while allowing patients to live at home. IOP is appropriate for moderate depression with addiction, for people stepping down from residential care, or when the person has a stable living environment and support system. Dual diagnosis IOP programs include both addiction counseling and psychiatric services.

Outpatient care with medication management

Standard outpatient treatment works well for mild to moderate depression with substance use disorder, especially when combined with antidepressant medication. This typically involves weekly therapy sessions, regular psychiatric check-ins for medication management, and support group participation. Outpatient care allows people to maintain work, family, and daily responsibilities while receiving treatment.

Choosing the right level of care

The appropriate level of care depends on several factors: severity of depression (mild vs. severe with suicidal thoughts), severity of addiction, previous treatment attempts and outcomes, strength of social support, co-occurring medical conditions, and safety concerns. A professional assessment by a dual diagnosis specialist can determine the best starting point. Many people move through multiple levels of care as they progress in recovery.

Antidepressant Medications in Recovery

SSRIs: the first-line treatment

Selective serotonin reuptake inhibitors (SSRIs) such as sertraline (Zoloft), fluoxetine (Prozac), and escitalopram (Lexapro) are the most commonly prescribed antidepressants for people in addiction recovery. They work by increasing serotonin availability in the brain, gradually improving mood, sleep, and motivation over 4–6 weeks. SSRIs are not addictive, do not produce a high, and have no abuse potential — making them fundamentally different from the substances being treated.

SNRIs and bupropion

Serotonin-norepinephrine reuptake inhibitors (SNRIs) like venlafaxine (Effexor) and duloxetine (Cymbalta) target both serotonin and norepinephrine, which can be helpful for depression with prominent fatigue or chronic pain. Bupropion (Wellbutrin) is another option that acts on dopamine and norepinephrine — it can help with depression, low energy, and is also used to support smoking cessation. None of these medications carry addiction risk.

Addressing the stigma around psychiatric medication

Many people in recovery resist antidepressants because they feel taking any medication contradicts sobriety. This misconception is dangerous. Antidepressants are not mood-altering substances in the way drugs of abuse are — they restore normal brain chemistry rather than creating artificial highs. Untreated depression is one of the strongest predictors of addiction relapse. Taking prescribed, non-addictive medication to manage a medical condition is not a failure of recovery — it supports it.

Why stopping psychiatric meds leads to relapse

A common and harmful pattern occurs when people in recovery stop their antidepressants because they feel better, believe they no longer need them, or face pressure from others to be "medication-free." When depression returns — often within weeks — the emotional pain drives them back to substances. Antidepressant treatment for co-occurring depression should be maintained for at least 12 months after stabilization, and many people benefit from long-term maintenance. Any changes to psychiatric medication should be made gradually under medical supervision.

Frequently Asked Questions About Depression and Addiction

What is dual diagnosis treatment for depression and addiction?

Dual diagnosis treatment addresses both depression and substance use disorders simultaneously through integrated care. This approach recognizes that mental health and addiction affect each other and must be treated together for lasting recovery. Treatment includes psychiatric care, medication management, therapy (CBT, DBT), and specialized counseling that addresses both conditions comprehensively.

Can depression cause substance abuse?

Yes, depression significantly increases the risk of substance abuse. Many people self-medicate depression symptoms with alcohol or drugs, seeking temporary relief from emotional pain, low energy, or insomnia. However, substance use worsens depression long-term by disrupting serotonin and dopamine regulation, creating a vicious cycle. Proper treatment addresses root causes of depression while providing healthier coping strategies than substances.

Will antidepressants interfere with addiction treatment?

No, appropriate antidepressant medication actively supports recovery. Quality dual diagnosis programs work with psychiatrists to find effective antidepressant treatment while addressing addiction. Medications like SSRIs and SNRIs are non-addictive and help stabilize mood, making it easier to engage in therapy and maintain sobriety. Never stop psychiatric medications without medical guidance.

How do I find a treatment center for depression and addiction?

Look for centers explicitly offering dual diagnosis or co-occurring disorder treatment. Verify they have licensed mental health professionals, psychiatric services, medication management capabilities, and experience treating both conditions together. Use our directory to filter for dual diagnosis programs, read reviews, and verify accreditation. Contact admissions teams to discuss your specific needs.

Is residential treatment necessary for depression and addiction?

Not always. Treatment level depends on severity of both conditions, previous treatment attempts, safety concerns, and support system. Some people do well with intensive outpatient care plus medication management. Residential treatment provides 24/7 support for severe depression, suicide risk, or when outpatient treatment hasn't succeeded. A professional assessment determines the most appropriate level of care.

Can addiction cause depression or does depression cause addiction?

The relationship is bidirectional — it works both ways. Depression can lead to substance abuse through self-medication, as people use drugs or alcohol to escape emotional pain. At the same time, chronic substance use alters brain chemistry in ways that cause or worsen depression — alcohol is a central nervous system depressant, stimulant withdrawal causes profound depression, and opioid use disrupts the brain's natural mood regulation. In many cases, both conditions develop and reinforce each other simultaneously, which is why integrated dual diagnosis treatment is essential for lasting recovery.

Will I need antidepressants forever?

Not necessarily. Many people take antidepressants for 12–24 months after their mood stabilizes, then gradually taper off under medical supervision. However, some people with recurrent major depression (three or more episodes) benefit from long-term maintenance medication. The decision depends on depression severity, number of past episodes, family history, and individual response to treatment. What is critical is never stopping antidepressants abruptly — doing so can cause withdrawal symptoms and trigger relapse in both depression and addiction. Always work with your prescribing psychiatrist to make any medication changes.

Medical Review and Sources

Medically Reviewed Updated April 10, 2026

Reviewed by licensed addiction specialists. Information reflects current clinical guidance.

Sources:SAMHSA·NIDA·CDC

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