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Updated: August 2026
Sources: SAMHSA, NIDA

Suboxone Clinic Near You: Buprenorphine Treatment for Opioid Addiction

Find a Suboxone clinic near you. Buprenorphine — sold under brand names Suboxone, Sublocade, Subutex, Zubsolv, and Brixadi — is the most-prescribed MAT for opioid use disorder. It is a partial mu-opioid agonist with a ceiling effect that dramatically reduces overdose risk vs. methadone. After the MAT Act of 2023 eliminated the X-waiver requirement, any licensed prescriber can prescribe buprenorphine in office-based settings (OBOT), via telehealth, or at retail pharmacies. Buprenorphine is a Schedule III controlled substance and is covered by Medicaid in all 50 states.

Found 7,145 treatment centers offering buprenorphine (suboxone) across the United States.

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Metro Treatment of Texas LP

Metro Treatment of Texas LP located in San Antonio, TX, offers outpatient detox and substance abuse therapy for both adults and young adults. The center delivers outpatient treatments involving methadone/buprenorphine or naltrexone, employing evidence-based methods like cognitive behavioral therapy, anger management, and brief interventions. This facility is dedicated to helping active military service members, individuals who have faced intimate partner violence, domestic violence, and survivors of sexual abuse. Customized programs are designed for both male and female clients. Committed to high-quality care and specialized assistance, this center strives to lead individuals towards sustainable recovery and enhanced well-being.

Metro Treatment of Texas LP

Metro Treatment of Texas LP, located in San Antonio, TX, provides comprehensive outpatient services for individuals struggling with substance use disorders and co-occurring mental health conditions. Their approach encompasses adults, young adults, and children, addressing a range of needs from general substance use to serious mental health illnesses and emotional disturbances. The center employs evidence-based practices such as cognitive behavioral therapy, anger management techniques, and brief intervention strategies to craft personalized treatment plans. Specialized programs are available for adult men and women, ensuring focused support. At Metro Treatment of Texas LP, client well-being is paramount, with medically supervised outpatient treatments including methadone, buprenorphine, or naltrexone available to all eligible individuals.

MetroHealth
Cleveland, OH

MetroHealth, located in Cleveland, OH, specializes in tailored substance use treatment programs designed for both adults and young adults. The center offers a variety of services, including intensive outpatient programs, standard outpatient care, and options for methadone, buprenorphine, or naltrexone treatments. Emphasizing cognitive behavioral therapy, the Matrix Model, and motivational interviewing, MetroHealth crafts a unique recovery plan for each individual, ensuring that the treatment is personalized. The center's strong focus on customized care distinguishes it, serving both male and female clients alike. If you are looking for thorough addiction treatment delivered with compassion and expertise, MetroHealth is committed to aiding you on your path to sustained sobriety.

Metropolitan Community Hlth Servs Inc

Metropolitan Community Hlth Servs Inc, located in Williamston, NC, provides outpatient treatment for substance use and offers specialized services for adults dealing with co-occurring substance use and serious mental health issues, as well as for children experiencing severe emotional disturbances. The center features therapy options such as outpatient methadone/buprenorphine and naltrexone treatments, along with standard outpatient services. Their methodologies include 12-step programs, anger management techniques, and brief intervention strategies. This facility also has specialized initiatives designed for adolescents, men, and women, accommodating adults and seniors of all genders. Metropolitan Community Hlth Servs Inc is committed to delivering personalized, high-quality care to support clients throughout their recovery journey.

Metropolitan Community Hlth Servs Inc

Metropolitan Community Hlth Servs Inc located in Washington, NC, delivers extensive treatment for adults dealing with substance use issues alongside serious mental health conditions or emotional challenges in children. The center provides outpatient programs, offering options such as methadone, buprenorphine, and naltrexone therapies, in addition to standard outpatient services. Their treatment strategy incorporates 12-step help, anger management techniques, and brief intervention methods, ensuring that care is customized to each individual’s needs. With specific programs directed toward adolescents, and adult men and women, the facility serves a wide range of populations. Adults and older adults of all genders can benefit from tailored treatment plans within a nurturing environment recognized for its commitment to quality care and personalized rehabilitation strategies.

MFI Recovery Center
Riverside, CA

Situated in Riverside, CA, the MFI Recovery Center provides various treatment options for substance use disorders aimed at both adults and children who also face mental health challenges. Their offerings encompass intensive outpatient programs, outpatient day treatment, and standard outpatient services. The center employs personalized strategies, including 12-step support, anger management sessions, and brief intervention techniques to meet the unique needs of each individual. MFI features special initiatives tailored for adolescents, men, and women, ensuring a wide range of services for its diverse population. Quality care is available for adults and seniors, regardless of gender, making MFI Recovery Center a reliable choice for thorough and compassionate addiction treatment.

MFI Recovery Center

Situated in Banning, CA, MFI Recovery Center specializes in extensive treatment for adults dealing with substance use issues, particularly those with co-existing serious mental health conditions and emotional challenges in children. The center features various programs, including intensive outpatient, outpatient, and partial hospitalization options, which integrate 12-step principles, anger management techniques, and short interventions. Programs designed specifically for adolescents, as well as adult men and women, are offered. Catering to adults and elderly individuals of all genders, this facility prioritizes excellent care and personalized treatment plans to foster long-term recovery.

MFI Recovery Center
Riverside, CA

Located in Riverside, CA, MFI Recovery Center is dedicated to providing tailored substance abuse treatment for adult men, seniors, and young adults within a nurturing residential environment. This center features various programs designed to address both substance use and concurrent serious mental health issues, as well as emotional challenges faced by children. MFI Recovery Center employs a holistic approach that incorporates 12-step methods, anger management, and brief intervention strategies, ensuring that each individual's needs are met effectively. Additionally, the center offers specialized support for clients who have endured intimate partner violence, domestic abuse, and sexual trauma, fostering a well-rounded path to recovery. Benefit from exceptional care and unwavering support at this esteemed rehabilitation center.

MFI Recovery Center

Situated in Murrieta, California, MFI Recovery Center provides extensive support for individuals of all ages battling substance use challenges, especially when these are coupled with mental health conditions. They offer a range of care levels including intensive outpatient, standard outpatient, and day treatment, drawing on proven therapeutic methods like 12-step facilitation, anger management strategies, and brief intervention techniques. MFI Recovery Center is distinguished by its tailored programs designed specifically for adolescents, adult men, and women, acknowledging the unique requirements of different demographics. The center's dedication to delivering high-quality, personalized recovery journeys positions it as a premier option for effective rehabilitation within the Murrieta community.

MFI Recovery Center
Riverside, CA

At MFI Recovery Center in Riverside, CA, we provide expert care for adult women facing the challenges of addiction alongside serious mental health conditions. Our programs are designed with your unique journey in mind, offering flexible durations from short-term to extended residential stays, all within a secure, female-only environment. We integrate proven methods like 12-step facilitation and anger management, alongside specialized support for survivors of intimate partner violence, domestic abuse, and sexual trauma. Our dedicated team offers compassionate and individualized support for adults, seniors, and young adults, ensuring a path to lasting recovery. Discover a place of healing and empowerment at MFI Recovery Center.

MFI Recovery Center

MFI Recovery Center, situated in Banning, CA, delivers extensive treatment solutions. The center offers both extended and brief residential stays for adults and adolescents facing addiction and simultaneous mental health challenges. Through methods like 12-step support, emotional regulation training, and concise therapeutic interventions, they customize care for each person. MFI Recovery Center is distinguished by its dedicated programs for adult males, adult females, and individuals affected by domestic or partner violence. Their commitment to high-standard, individualized care aims to guide clients toward lasting recovery.

MFI Recovery Center
Riverside, CA

MFI Recovery Center, situated in Riverside, CA, delivers a complete suite of addiction recovery services for adults and adolescents. Their expertise encompasses detox and the management of substance dependencies, alongside specialized support for those navigating concurrent mental health challenges and addiction. They offer extended residential stays and constant oversight, utilizing methods like 12-step engagement and emotional regulation training. Tailored programs are available for adult men and women, and also for individuals impacted by domestic abuse. MFI Recovery Center fosters a nurturing setting to deliver excellent care, positioning it as a prime selection for those pursuing impactful and empathetic recovery solutions.

Metro Treatment of New Hampshire

Metro Treatment of New Hampshire, situated in Manchester, NH, provides outpatient care for substance use issues, featuring programs that include outpatient methadone/buprenorphine or naltrexone therapies. The center employs evidence-based methods such as cognitive behavioral therapy, motivational interviewing, and strategies for preventing relapse. With tailored programs for adult males, adult females, and individuals facing both mental health and substance use challenges, this facility serves a wide variety of clients. By offering quality support to adults and young adults of all genders, Metro Treatment of New Hampshire aims to assist individuals in their recovery process in a nurturing setting.

Metropolitan Rehabilitation Clinics

Metropolitan Rehabilitation Clinics in Oak Park, MI, provides an extensive selection of outpatient services aimed at those needing detoxification, treatment for substance use disorders, and assistance for co-occurring mental health issues. This center features outpatient detoxification, methadone and buprenorphine therapies, and dedicated programs for both adults and young adults facing challenges related to intimate partner violence. Utilizing diverse treatment methods such as 12-step facilitation and anger management, the facility serves clients of all genders. Metropolitan Rehabilitation Clinics emphasizes high-quality care and personalized brief interventions designed to meet the unique needs of each individual.

Metro Treatment of Utah LP

Metro Treatment of Utah LP, located in Woods Cross, UT, focuses on outpatient substance abuse services, particularly methadone, buprenorphine, and naltrexone-assisted treatment. Their approach includes brief interventions, motivational enhancement, and relapse avoidance techniques. The facility offers distinct programs for active military members, adult males, and adult females. Serving a broad demographic of adults and young adults, Metro Treatment of Utah LP emphasizes individualized care using scientifically supported methods. For those in need of complete addiction recovery support, this establishment offers a nurturing and successful setting.

Metro Treatment of Minnesota LP

Metro Treatment of Minnesota LP in Burnsville, MN, delivers comprehensive outpatient substance use disorder services. Their offerings include medication-assisted treatment utilizing methadone, buprenorphine, or naltrexone. The center emphasizes evidence-based therapeutic modalities such as cognitive behavioral therapy, motivational interviewing, and relapse prevention strategies. Tailored programming is available for adult men and women, and they cater to both adult and young adult populations. Metro Treatment of Minnesota LP is committed to providing high-quality, individualized care within a supportive setting, guiding each person toward sustained recovery. For those pursuing effective, personalized addiction treatment, this center is devoted to fostering long-term sobriety.

Metro Treatment of Kentucky LP

Metro Treatment of Kentucky LP, located in Covington, KY, specializes in outpatient programs designed for individuals struggling with substance use, including both adults and young adults. The center caters to the unique needs of adult men and women, along with clients who have faced intimate partner violence, creating a nurturing and secure atmosphere for recovery. The treatment methods employed encompass anger management, brief intervention strategies, and cognitive behavioral therapy, all aiming for a comprehensive healing experience. Individuals can receive either outpatient methadone/buprenorphine or naltrexone treatments, in addition to standard outpatient services, ensuring that they receive compassionate and research-based care. At Metro Treatment of Kentucky LP, the focus is on delivering high-quality, personalized support to assist each client on their path to recovery.

MH Assoc of Westchester Co Inc

MH Assoc of Westchester Co Inc located in White Plains, NY, provides outpatient treatment for adults dealing with substance use issues, particularly for those facing serious mental health challenges or emotional disturbances in children. The center offers outpatient treatment options including methadone, buprenorphine, or naltrexone, in conjunction with standard outpatient services. They feature specialized programs designed for active duty military personnel, teenagers, and adult males. Treatment methods include 12-step programs, anger management strategies, and brief intervention techniques. The center caters to both men and women, as well as children and teenagers, emphasizing high-quality care and serving as a crucial support resource for individuals in need of thorough addiction treatment solutions.

Metro Treatment of Minnesota LP

Metro Treatment of Minnesota LP in Saint Paul, MN, provides accessible outpatient addiction care, featuring medication-assisted treatment options like methadone, buprenorphine, and naltrexone. Their therapeutic approach centers on proven methods such as cognitive behavioral therapy, motivational interviewing, and strategies for preventing relapse. This center offers specialized support for adult men and women, serving a diverse population of adults and young adults, encompassing both male and female clients. By prioritizing personalized treatment strategies and employing scientifically validated techniques, Metro Treatment of Minnesota LP is dedicated to delivering effective recovery services.

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Metro Treatment of Utah LP in Saint George, UT, provides outpatient detoxification and treatment for substance use disorders aimed at both adults and young adults. The center is dedicated to tailored care, employing techniques such as anger management, cognitive behavioral therapy, and motivational incentives through contingency management. Prioritizing high-quality treatment, this facility serves both men and women in their journey towards recovery from addiction. Whether individuals are in need of detoxification services or require ongoing medication-assisted treatment options like methadone, buprenorphine, or naltrexone, the center is committed to offering extensive support for those aiming to achieve sobriety.

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Situated in Arabi, LA, the Metropolitan Human Services District provides focused treatment for adults grappling with substance use issues alongside mental health challenges, as well as support for children facing serious emotional difficulties. Their range of services encompasses intensive outpatient care, standard outpatient support, and medication-assisted treatment with methadone, buprenorphine, or naltrexone. By employing evidence-supported methodologies such as cognitive behavioral therapy, contingency management, and the Matrix Model, this center delivers customized care for adolescents, adults, and older adults. The Metropolitan Human Services District prioritizes personalized treatment strategies and offers gender-specific programs for both men and women, ensuring comprehensive and effective support for sustained recovery.

Frequently Asked Questions

What is buprenorphine and how does it treat opioid addiction?
Buprenorphine is a partial opioid agonist medication approved by the FDA for treating opioid use disorder. It binds to the same receptors as heroin and fentanyl but produces a much weaker effect, reducing cravings and withdrawal symptoms without causing intense euphoria. Buprenorphine has a ceiling effect, meaning its opioid effects plateau at moderate doses, making it safer than methadone in terms of overdose risk.
What is the difference between Suboxone and Subutex?
Suboxone contains two active ingredients — buprenorphine and naloxone — while Subutex contains only buprenorphine without naloxone. The naloxone in Suboxone is included as an abuse deterrent; it remains inactive when taken sublingually as prescribed but triggers withdrawal if the medication is injected. Subutex is generally reserved for patients who cannot tolerate naloxone, such as pregnant women.
What is a Sublocade injection and how does it work?
Sublocade is a once-monthly injectable form of buprenorphine administered as a subcutaneous injection in the abdominal area. After injection, the medication forms a solid deposit under the skin that slowly releases buprenorphine over the course of a month. This eliminates daily dosing and removes the possibility of missed doses or medication diversion.
What are the common side effects of Suboxone?
Common Suboxone side effects include headache, nausea, constipation, insomnia, sweating, and mouth numbness or pain from sublingual administration. Some patients also experience dizziness, drowsiness, and blurred vision, particularly when starting treatment. Most side effects diminish within the first few weeks as the body adjusts. Patients should report difficulty breathing or signs of allergic reaction immediately.
What happens during Suboxone withdrawal?
Suboxone withdrawal occurs when a patient stops taking the medication abruptly after prolonged use, with symptoms including muscle aches, anxiety, insomnia, nausea, and irritability. A medically supervised taper is strongly recommended, typically reducing the dose by small increments over weeks or months. The risk of opioid relapse is significantly higher during unsupervised discontinuation.
How does Suboxone compare to methadone?
Suboxone and methadone are both effective for opioid use disorder but differ in key ways. Methadone is a full opioid agonist dispensed daily at licensed clinics, while Suboxone is a partial agonist that can be prescribed by qualified physicians and taken at home. Suboxone carries a lower overdose risk due to its ceiling effect and offers greater convenience, though methadone may be more appropriate for patients with severe, long-standing dependence.
How can I find a Suboxone clinic or doctor near me?
The most reliable way to find a Suboxone provider is through SAMHSA's online treatment locator at findtreatment.gov, which allows you to search by location and filter for buprenorphine providers. Many primary care offices, addiction treatment centers, and telehealth platforms now offer Suboxone prescriptions following the elimination of the federal X-waiver requirement in early 2023.
What is Zubsolv and how is it different from Suboxone?
Zubsolv is a brand-name buprenorphine and naloxone sublingual tablet that features a mint flavor and dissolves faster under the tongue than other options. Due to its higher bioavailability, Zubsolv uses different dosing strengths — a Zubsolv 5.7 mg/1.4 mg tablet is considered equivalent to a Suboxone 8 mg/2 mg dose. Patients switching between products should work closely with their prescriber for correct dose conversion.
Does Medicaid cover Suboxone treatment?
Yes — Medicaid covers buprenorphine (including Suboxone, Sublocade, Subutex, Zubsolv, and Brixadi) for opioid use disorder in all 50 states, as required by the SUPPORT Act of 2018. Medicaid is the largest single payer for MAT in the US. Coverage details vary by state — some require prior authorization or limit certain formulations. Many OBOT clinics accept Medicaid directly; telehealth Suboxone providers also bill Medicaid in most states. Bring your Medicaid card to your intake appointment.
Can I get Suboxone through telehealth?
Yes. After the MAT Act of 2023 permanently eliminated the X-waiver requirement, any licensed prescriber can prescribe Suboxone via telehealth in most states. The DEA also extended COVID-era telehealth flexibilities through at least 2025, allowing virtual Suboxone induction without a prior in-person visit. Several specialty platforms — Bicycle Health, Ophelia, Workit Health, Boulder Care — offer Medicaid-accepting telehealth Suboxone treatment. Telehealth has dramatically expanded access in rural and underserved areas with no nearby OBOT physicians.

About Buprenorphine (Suboxone)

Buprenorphine is classified as a partial opioid agonist, meaning it activates opioid receptors in the brain but to a much lesser degree than full agonists such as heroin, fentanyl, or oxycodone. This partial activation suppresses withdrawal symptoms and reduces cravings without producing dangerous respiratory depression or intense euphoria. Buprenorphine also has an unusually high binding affinity for the mu-opioid receptor, effectively blocking other opioids from attaching — providing a protective effect against relapse-related overdose.

How Buprenorphine Works

One of the defining features of buprenorphine is its ceiling effect — after a certain dose threshold, increasing the amount does not produce additional opioid effects. This dramatically reduces the risk of fatal overdose compared to methadone or illicit opioids. The ceiling effect, combined with its long duration of action (24 to 72 hours), makes buprenorphine one of the safest and most effective tools in medication-assisted treatment (MAT). Approved by the FDA in 2002, buprenorphine was a breakthrough because it could be prescribed in outpatient settings rather than requiring daily clinic visits.

Buprenorphine Brand Comparison: Suboxone, Subutex, Sublocade, Zubsolv, Brixadi

Buprenorphine is available under several FDA-approved brand names, each with distinct formulations, dosing schedules, and clinical use cases. The comparison below highlights the key differences:

BrandActive ingredientFormFrequencySettingFDA yearBest for
SuboxoneBuprenorphine + naloxoneSublingual film / tabletDailyOBOT, telehealth, retail pharmacy2002Most prescribed; naloxone deters injection misuse
SubutexBuprenorphine (alone)Sublingual tabletDailyOBOT2002Pregnancy; documented naloxone sensitivity
SublocadeBuprenorphine extended-releaseSubcutaneous injection (ATRIGEL depot)MonthlyClinic-administered2017No daily dosing; eliminates diversion risk
ZubsolvBuprenorphine + naloxoneSublingual tablet (higher bioavailability)DailyOBOT2013Faster dissolution; mint flavor; lower mg/dose
BrixadiBuprenorphine extended-releaseSubcutaneous injectionWeekly or monthlyClinic2023Newer alternative to Sublocade; weekly option for induction

All five medications are Schedule III controlled substances and equivalent in clinical efficacy at appropriate doses. The choice depends on adherence patterns, lifestyle, insurance coverage, and clinical context (e.g., pregnancy, prior injection use, daily-dosing burden). Many patients begin on sublingual Suboxone for stabilization and transition to monthly Sublocade or weekly Brixadi after sustained recovery.

Buprenorphine Side Effects

Common buprenorphine side effects include:

  • Headache and dizziness
  • Nausea and vomiting, especially during induction
  • Constipation and insomnia
  • Excessive sweating
  • Mouth numbness or oral discomfort from sublingual formulations

More serious side effects may include respiratory depression (particularly when combined with benzodiazepines or alcohol), liver problems, and allergic reactions. For most patients, side effects are mild and resolve within one to two weeks. The benefits in preventing relapse and overdose death significantly outweigh the risks.

Buprenorphine Dosage and Induction

Treatment begins with an induction phase where the patient must be in mild to moderate opioid withdrawal. Common induction doses range from 2 mg to 8 mg on the first day, with increases over the following days. Most patients stabilize on 8 mg to 24 mg per day, with 16 mg being the most commonly prescribed dose. Research suggests doses of 16 mg or higher are associated with better retention and outcomes. Dosage should always be adjusted under medical supervision.

Buprenorphine/Naloxone Combination

Many buprenorphine formulations include naloxone as an abuse deterrent. When taken sublingually as directed, naloxone has very low bioavailability and produces no clinical effect. However, if someone attempts to inject the medication, the naloxone component becomes fully active and triggers severe withdrawal. This design discourages injection misuse while having no impact on patients who take the medication correctly. The combination is the standard first-line formulation for opioid addiction treatment.

Suboxone: Sublingual Buprenorphine

Suboxone is the most recognized brand name for buprenorphine-naloxone and is most commonly dispensed as a sublingual film (Suboxone strips) that dissolves under the tongue. Suboxone has transformed opioid treatment by enabling millions of patients to receive effective pharmacotherapy in outpatient settings without the daily clinic visits required by methadone programs.

Suboxone Side Effects

Commonly reported Suboxone side effects include headache, nausea, tongue or mouth irritation, constipation, insomnia, sweating, and decreased libido. The sublingual film can cause irritation or small sores inside the mouth — rotating placement between under the tongue and against the cheek helps minimize this. Patients should not eat, drink, or smoke while the film is dissolving.

Suboxone Strips: Film vs. Tablet

Suboxone strips (sublingual film) have largely replaced the original tablet form. The film dissolves more quickly (two to four minutes), provides more consistent absorption, and is harder to divert due to individual foil packaging. Generic buprenorphine-naloxone tablets are often less expensive and may be preferred for cost reasons. Both are therapeutically equivalent when taken as prescribed.

Suboxone Treatment Programs

Comprehensive Suboxone treatment typically includes three phases:

  • Induction: Initial dosing under medical supervision, requiring the patient to be in early withdrawal
  • Stabilization: Dose adjustment until cravings and withdrawal are minimal, usually one to two months
  • Maintenance: Stable dosing for an extended period — often a year or longer — combined with counseling and behavioral therapy

Evidence consistently shows that longer treatment durations are associated with better outcomes. Most addiction medicine experts recommend a minimum of one to two years of maintenance therapy.

Find a Suboxone Clinic Near You — OBOT & Telehealth Options

Finding a Suboxone clinic has become significantly easier since the federal government eliminated the X-waiver requirement in January 2023, meaning any provider with a standard DEA license can now prescribe Suboxone. Patients can search SAMHSA's treatment locator at findtreatment.gov or use our directory to locate nearby facilities that offer buprenorphine-based treatment.

Suboxone Doctors Near Me

Beyond SAMHSA's locator, many state health departments maintain directories of addiction treatment providers. Telehealth has dramatically expanded access — several platforms now offer virtual Suboxone consultations, which is especially valuable for patients in rural areas. When selecting a provider, look for those offering comprehensive treatment including counseling, not just medication prescriptions.

Suboxone Withdrawal and Tapering

Suboxone withdrawal can include muscle aches, anxiety, insomnia, nausea, sweating, and intense opioid cravings. A gradual, medically supervised taper is recommended — typically reducing the dose by 10 to 25 percent every one to four weeks. Slower tapers over several months produce fewer symptoms and lower relapse rates. There is no medically mandated time limit for Suboxone treatment, and many patients benefit from indefinite maintenance.

Suboxone vs Methadone

Suboxone can be prescribed in office settings and taken at home, carries lower overdose risk due to its ceiling effect, and offers greater scheduling flexibility. Methadone is a full agonist that may be more effective for severe, long-standing dependence but must be dispensed at licensed clinics with daily visits. Neither is inherently superior — the best choice keeps the patient in treatment. Some patients may also benefit from naltrexone, a non-opioid alternative.

Sublocade: Monthly Buprenorphine Injection

Sublocade delivers buprenorphine as a once-monthly subcutaneous injection in the abdominal area using the ATRIGEL delivery system, which forms a solid biodegradable depot that slowly releases medication. Patients must first stabilize on sublingual buprenorphine (8 mg+ daily) for at least seven days. Treatment typically begins with two 300 mg injections, followed by maintenance on 300 mg or 100 mg. Sublocade eliminates concerns about daily adherence, missed doses, and medication diversion.

Sublocade Side Effects

The most common Sublocade side effects are injection-site reactions (pain, itching, redness, or a noticeable lump), nausea, constipation, headache, and fatigue. The injection-site lump is normal and gradually diminishes as medication is absorbed. Patients should avoid rubbing or massaging the site. Elevated liver enzymes may also occur but are usually mild and transient.

Subutex: Buprenorphine Without Naloxone

Subutex was the original brand-name buprenorphine product. While the brand has been discontinued, generic buprenorphine-only tablets remain available. Buprenorphine monotherapy is typically reserved for pregnant patients (to avoid naloxone exposure to the fetus), patients with documented naloxone sensitivity, or sometimes during the induction phase before transitioning to the combination product.

Subutex vs Suboxone

The primary difference is the absence of naloxone in Subutex. Because Subutex lacks the abuse-deterrent naloxone component, it may carry slightly higher diversion risk, and many insurance formularies prioritize the combination as the default. Current clinical guidelines favor buprenorphine-only formulations primarily for pregnancy and naloxone sensitivity.

Zubsolv: Alternative Buprenorphine Brand

Zubsolv is a buprenorphine-naloxone sublingual tablet featuring a mint flavor and faster dissolution (under two minutes). Due to enhanced bioavailability, Zubsolv uses different dose strengths — a 5.7 mg/1.4 mg tablet equals a Suboxone 8 mg/2 mg dose. Zubsolv is available in multiple strengths for flexible dosing during both induction and maintenance.

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Medically Reviewed Updated August 2026

Reviewed by licensed addiction specialists. Information reflects current clinical guidance.

Sources:SAMHSA·NIDA·CDC

Need immediate help? Call SAMHSA: 1-800-662-4357 (24/7, free)