NWVCIL Logo
Medically Reviewed Content
Updated: August 2026
Sources: SAMHSA, NIDA

Suboxone Clinic Near You: Buprenorphine Treatment for Opioid Addiction

Find a Suboxone clinic near you. Buprenorphine — sold under brand names Suboxone, Sublocade, Subutex, Zubsolv, and Brixadi — is the most-prescribed MAT for opioid use disorder. It is a partial mu-opioid agonist with a ceiling effect that dramatically reduces overdose risk vs. methadone. After the MAT Act of 2023 eliminated the X-waiver requirement, any licensed prescriber can prescribe buprenorphine in office-based settings (OBOT), via telehealth, or at retail pharmacies. Buprenorphine is a Schedule III controlled substance and is covered by Medicaid in all 50 states.

Found 7,145 treatment centers offering buprenorphine (suboxone) across the United States.

Need Help Finding the Right Treatment Center?

Speak with a compassionate specialist now - 100% free & confidential

Call +1 (833) 244-3031
Available 24/7
All 50 States
Filters:

Showing 21 of 7145 results

Michaels House
Palm Springs, CA

Michael's House, located in Palm Springs, California, provides a wide range of rehabilitation services for both adults and young adults struggling with substance use disorders along with associated mental health challenges. The center features inpatient detox and treatment within a hospital setting, catering specifically to adult men, adult women, and those who have faced trauma. Emphasizing methods such as 12-step facilitation, anger management, and brief intervention, this facility guarantees individualized care designed to meet the unique needs of each patient. With services available for both genders, Michael's House is committed to offering effective treatment in a nurturing atmosphere to support lasting recovery.

Michaels House
Palm Springs, CA

Situated in Palm Springs, CA, Michaels House delivers an extensive variety of treatment services for substance use disorders aimed at adults and young adults. The center focuses on addressing co-occurring substance use issues alongside significant mental health challenges or emotional problems in children. With a range of options such as intensive outpatient programs, outpatient day treatment, and partial hospitalization, Michaels House emphasizes personalized treatment plans that cater to the unique requirements of each individual. The facility provides specialized programs for adult men, adult women, and those who have faced trauma. By incorporating methods like 12-step facilitation, anger management, and brief interventions, Michaels House guarantees top-notch care for all clients pursuing recovery.

Mid Coast/Parkview Health

Mid Coast/Parkview Health, located in Brunswick, ME, provides an array of addiction rehabilitation services specifically designed for both adults and older adults. The center features detox services, treatment for substance use disorders, and focused care for individuals facing dual diagnosis challenges. Treatment options encompass intensive outpatient programs as well as outpatient detoxification. The facility employs proven strategies such as cognitive behavioral therapy and motivational incentives to aid individuals on their recovery journey. With tailored programs for adult males, adult females, and those with co-occurring mental health issues, Mid Coast/Parkview Health is dedicated to delivering personalized treatment. Their commitment to high-quality care and gender-specific offerings makes this center a reliable option for those looking for effective recovery solutions.

Mid Hudson Valley Div of WMC

The Mid Hudson Valley Division of WMC, located in Poughkeepsie, NY, provides extensive treatment options for substance use disorders through its inpatient hospital services and around-the-clock care programs. This center employs various specialized techniques, including 12-step programs, anger management, and cognitive behavioral therapy, to meet the unique needs of each individual. It also features specific programs designed for active military personnel, as well as separate services for adult men and women, reflecting its commitment to serving a wide range of individuals. The facility welcomes adults and young adults of all genders, fostering a nurturing and inclusive atmosphere. Clients can anticipate receiving top-notch care and evidence-based therapies to support them on their path to recovery.

Mid Hudson Valley Div of WMC

The Mid Hudson Valley Division of WMC, located in Poughkeepsie, NY, provides a range of extensive treatment options for addiction. This center features hospital-based inpatient detoxification services and addresses substance use disorders while also accommodating adults with serious mental health issues and children with emotional challenges. It offers tailored programs for men, women, and individuals impacted by domestic violence, ensuring a broad spectrum of services. Utilizing methods such as 12-step programs and anger management, the center prioritizes personalized support for both adults and younger individuals. Committed to high-quality care grounded in evidence-based practices, this facility offers compassionate and effective rehabilitation for all clients.

Mid State Health Center

Mid State Health Center, based in Plymouth, NH, delivers extensive treatment options for adults and young adults facing substance use challenges. This establishment features programs such as intensive outpatient care, outpatient services, and treatments involving methadone, buprenorphine, or naltrexone. With a focus on specialized methods including 12-step support, anger management, and brief intervention strategies, the center serves both men and women. Furthermore, Mid State Health Center includes dedicated programs for pregnant and postpartum women, ensuring customized care for every client. The center's dedication to high-quality services and a variety of treatment pathways positions it as an essential asset for individuals in search of supportive and effective addiction recovery solutions.

Mid State Health Center

Mid State Health Center, situated in Plymouth, NH, delivers extensive addiction recovery services for adults and young adults. Their offerings encompass outpatient care such as medication-assisted treatment (methadone/buprenorphine or naltrexone), general outpatient programs, brief counseling, cognitive behavioral therapy, and motivational strategies. They also feature a dedicated program for expectant and new mothers. Mid State Health Center is equipped to address the diverse requirements of every patient, serving both male and female individuals with their evidence-based and individualized approach to care. For those in search of impactful and tailored addiction treatment, Mid State Health Center stands ready to assist in your path to wellness.

Middlesex Recovery PC

Middlesex Recovery PC, located in Norton, MA, delivers dedicated treatment for substance use issues among both adults and young adults. The facility offers various outpatient services, such as treatments involving methadone, buprenorphine, and naltrexone, alongside standard outpatient programs and customized care plans. Incorporating techniques like cognitive behavioral therapy, motivational interviewing, and counseling specific to substance use disorders, this center is committed to meeting the unique requirements of each client. With a strong emphasis on personalized strategies, Middlesex Recovery PC serves both men and women in search of thorough and effective solutions for addiction recovery. Discover high-quality care and individualized assistance at this esteemed rehabilitation center.

Michigan Therapeutic Consultants PC

Michigan Therapeutic Consultants PC, located in Gaylord, MI, specializes in providing targeted treatment programs for substance use issues designed for adult men, adult women, and active duty military members. Emphasizing intensive outpatient care, the facility also offers outpatient services, including methadone, buprenorphine, and naltrexone treatments. Clients benefit from a variety of evidence-based methodologies such as brief interventions, cognitive behavioral therapy, and motivational incentives through contingency management. The center caters to both adults and young adults, ensuring personalized care tailored to the needs of male and female clients. Michigan Therapeutic Consultants PC is committed to offering exceptional, all-encompassing treatment that aids individuals in their recovery journey.

Mid Columbia Center for Living

Mid Columbia Center for Living, located in The Dalles, OR, provides various treatment options for substance use disorders alongside specialized care for individuals with concurrent mental health issues, suitable for both adults and children. The center features intensive outpatient and outpatient programs, offering treatments like methadone and buprenorphine. Their approach is personalized, employing evidence-based methods including 12-step facilitation, brief intervention, and cognitive behavioral therapy. The center also offers distinct programs designed for adult men, adult women, and clients facing dual diagnoses, accommodating adults and seniors of diverse genders. Emphasizing high-quality care and individualized approaches, this facility is dedicated to fostering recovery and promoting overall well-being.

Michigan Therapeutic Consultants PC

Located in Mount Pleasant, MI, Michigan Therapeutic Consultants PC specializes in tailored substance use treatment programs designed for both adults and young adults. The center offers a range of services, including intensive outpatient, outpatient care, as well as outpatient options using methadone, buprenorphine, or naltrexone. Emphasizing evidence-based practices such as cognitive behavioral therapy and contingency management, the facility is committed to providing high-quality treatment. Michigan Therapeutic Consultants PC also features distinct programs for active duty military members and caters to the unique needs of adult men and women, ensuring a well-rounded and personalized rehabilitation experience for clients seeking effective addiction recovery solutions.

Micah House
Minneapolis, MN

Micah House, situated in Minneapolis, MN, delivers a complete spectrum of care for addiction, transitional living, and dual diagnosis challenges affecting adults and youth. This center features intensive outpatient, extended residential stays, and standard outpatient services, utilizing methodologies such as 12-step guidance, emotional regulation training, and cognitive-behavioral techniques. Specialized services are available for adult males and females, and for those impacted by relationship violence. Catering to adults and older adolescents of any gender, Micah House is dedicated to providing excellent assistance and recovery in a supportive setting.

MH/MR of Tarrant County

MH/MR of Tarrant County in Fort Worth, TX, delivers extensive rehabilitative support. They address substance abuse with detoxification and specialized programs for those facing dual diagnoses of addiction and severe mental health conditions. Services are provided through residential detoxification, brief residential stays, and extended residential care. Employing proven methods like the Matrix Model, motivational interviewing, and relapse prevention techniques, the center serves adult men, adult women, and individuals with co-occurring disorders. Committed to high-quality care for adults and young adults, regardless of gender, MH/MR of Tarrant County is devoted to guiding individuals toward sustained recovery.

Middle Peninsula/Northern Neck CSB

Middle Peninsula/Northern Neck CSB in Tappahannock, VA, provides a wide array of addiction recovery services for adults and seniors. This center features intensive outpatient programming, regular outpatient services, and detoxification options. Emphasizing 12-step support, anger management, and brief intervention techniques, the facility addresses the needs of individuals facing both mental health challenges and substance use disorders. Moreover, it is experienced in working with adolescents and those dealing with simultaneous pain management issues and substance dependencies, offering personalized programs for both male and female clients. The facility's commitment to quality care and variety of treatment modalities establish it as an essential resource for individuals pursuing effective rehabilitation in Tappahannock.

Middle Peninsula/Northern Neck CSB

Middle Peninsula/Northern Neck CSB in Gloucester, VA, delivers extensive addiction treatment for individuals of all ages facing co-occurring mental health challenges. Their services include robust outpatient options and intensive programs, complemented by detoxification support. Employing methods like 12-step facilitation and anger management, they craft customized recovery plans. Dedicated tracks for teens and older adults, alongside specialized care for those with concurrent pain and substance use issues, underscore their commitment to all-encompassing recovery. Prioritizing excellence and individualized support, this center is devoted to guiding clients toward lasting wellness.

Placeholder image

MH Providers of Western Queens Inc, located in Woodside, NY, provides a wide range of treatment options for substance use disorders and addresses co-existing mental health conditions in adults and emotional challenges in children. The center features outpatient programs that offer treatments like methadone, buprenorphine, and naltrexone, and emphasizes personalized care through methods such as 12-step programs, anger management sessions, and brief therapeutic interventions. Additionally, specialized initiatives are available for adolescents, as well as adult men and women, to ensure focused support for each individual. Open to all genders, the facility fosters a welcoming and supportive atmosphere conducive to recovery and healing for both adults and youth.

Placeholder image

Located in Miami, FL, Miami Dade CAHSD offers extensive treatment services for individuals dealing with substance use issues. The center provides a variety of recovery options, including long-term residential care, outpatient support, and day programs, with a focus on 12-step methods, anger management, and cognitive behavioral techniques. Special programs are designed for adult men, adult women, and individuals who have faced trauma. Emphasizing personalized care, this facility customizes its approach to address each client's unique challenges. Serving both genders, Miami Dade CAHSD fosters a welcoming and supportive atmosphere for those on the path to overcoming addiction and reclaiming their lives.

Placeholder image

Miami Dade Community Services Inc, located in Miami, FL, provides a variety of evidence-based rehabilitation programs aimed at addressing substance use disorders and associated mental health challenges in both adults and children. Their offerings include intensive outpatient services, outpatient care, and day treatment, which integrate elements such as 12-step support, anger management, and concise therapeutic interventions. The center has tailored programs for active military members as well as specific groups for adult men and women, ensuring that it meets the needs of a wide range of individuals. Catering to clients across all genders, this facility emphasizes personalized treatment to facilitate healing and recovery. Miami Dade Community Services Inc remains a reliable option for those in search of comprehensive and effective rehabilitation solutions.

Placeholder image

Michiana Behavioral Health, situated in Plymouth, Indiana, stands as a leading addiction treatment center. They deliver extensive care for individuals battling substance abuse, chemical dependency, and co-occurring psychological disorders, serving both adolescents and adults. The facility offers inpatient medical detox and therapeutic services, emphasizing the 12-step model, cognitive behavioral techniques, and strategies for sustained sobriety. Michiana Behavioral Health also features distinct programs designed for active military members, adult men, and women. Their dedication to high-quality, personalized recovery plans positions them as an excellent option for adults and young adults pursuing a life free from addiction.

Placeholder image

At Mid Coast/Parkview Health in Damariscotta, ME, adults and seniors facing addiction and co-occurring mental health challenges discover a range of complete recovery support. Their offerings encompass detox services, structured outpatient treatment, and less intensive outpatient detox options. Employing proven methods such as cognitive behavioral therapy and contingency management, they guide individuals toward healing. The facility distinguishes itself with distinct programs designed for adult men, adult women, and those managing dual diagnoses, ensuring personalized care plans. By emphasizing brief intervention and motivational rewards, Mid Coast/Parkview Health delivers effective and high-standard treatment for all individuals pursuing sobriety.

Placeholder image

Mid Columbia Center for Living, located in Hood River, OR, delivers thorough recovery programs focused on addiction and intertwined mental health conditions affecting both young people and adults. The center offers various levels of care, including intensive outpatient services, general outpatient support, and medication-assisted treatment options such as methadone, buprenorphine, or naltrexone. Employing evidence-based approaches like 12-step integration, motivational interviewing, and cognitive behavioral therapy, the center creates customized plans for each person. Specific support is available for adult men, adult women, and individuals facing dual diagnoses of mental health and substance use challenges. Catering to a broad age range from adults to seniors and all genders, this establishment prioritizes high-quality, individualized treatment designed to guide each person through their personal path to wellness.

Frequently Asked Questions

What is buprenorphine and how does it treat opioid addiction?
Buprenorphine is a partial opioid agonist medication approved by the FDA for treating opioid use disorder. It binds to the same receptors as heroin and fentanyl but produces a much weaker effect, reducing cravings and withdrawal symptoms without causing intense euphoria. Buprenorphine has a ceiling effect, meaning its opioid effects plateau at moderate doses, making it safer than methadone in terms of overdose risk.
What is the difference between Suboxone and Subutex?
Suboxone contains two active ingredients — buprenorphine and naloxone — while Subutex contains only buprenorphine without naloxone. The naloxone in Suboxone is included as an abuse deterrent; it remains inactive when taken sublingually as prescribed but triggers withdrawal if the medication is injected. Subutex is generally reserved for patients who cannot tolerate naloxone, such as pregnant women.
What is a Sublocade injection and how does it work?
Sublocade is a once-monthly injectable form of buprenorphine administered as a subcutaneous injection in the abdominal area. After injection, the medication forms a solid deposit under the skin that slowly releases buprenorphine over the course of a month. This eliminates daily dosing and removes the possibility of missed doses or medication diversion.
What are the common side effects of Suboxone?
Common Suboxone side effects include headache, nausea, constipation, insomnia, sweating, and mouth numbness or pain from sublingual administration. Some patients also experience dizziness, drowsiness, and blurred vision, particularly when starting treatment. Most side effects diminish within the first few weeks as the body adjusts. Patients should report difficulty breathing or signs of allergic reaction immediately.
What happens during Suboxone withdrawal?
Suboxone withdrawal occurs when a patient stops taking the medication abruptly after prolonged use, with symptoms including muscle aches, anxiety, insomnia, nausea, and irritability. A medically supervised taper is strongly recommended, typically reducing the dose by small increments over weeks or months. The risk of opioid relapse is significantly higher during unsupervised discontinuation.
How does Suboxone compare to methadone?
Suboxone and methadone are both effective for opioid use disorder but differ in key ways. Methadone is a full opioid agonist dispensed daily at licensed clinics, while Suboxone is a partial agonist that can be prescribed by qualified physicians and taken at home. Suboxone carries a lower overdose risk due to its ceiling effect and offers greater convenience, though methadone may be more appropriate for patients with severe, long-standing dependence.
How can I find a Suboxone clinic or doctor near me?
The most reliable way to find a Suboxone provider is through SAMHSA's online treatment locator at findtreatment.gov, which allows you to search by location and filter for buprenorphine providers. Many primary care offices, addiction treatment centers, and telehealth platforms now offer Suboxone prescriptions following the elimination of the federal X-waiver requirement in early 2023.
What is Zubsolv and how is it different from Suboxone?
Zubsolv is a brand-name buprenorphine and naloxone sublingual tablet that features a mint flavor and dissolves faster under the tongue than other options. Due to its higher bioavailability, Zubsolv uses different dosing strengths — a Zubsolv 5.7 mg/1.4 mg tablet is considered equivalent to a Suboxone 8 mg/2 mg dose. Patients switching between products should work closely with their prescriber for correct dose conversion.
Does Medicaid cover Suboxone treatment?
Yes — Medicaid covers buprenorphine (including Suboxone, Sublocade, Subutex, Zubsolv, and Brixadi) for opioid use disorder in all 50 states, as required by the SUPPORT Act of 2018. Medicaid is the largest single payer for MAT in the US. Coverage details vary by state — some require prior authorization or limit certain formulations. Many OBOT clinics accept Medicaid directly; telehealth Suboxone providers also bill Medicaid in most states. Bring your Medicaid card to your intake appointment.
Can I get Suboxone through telehealth?
Yes. After the MAT Act of 2023 permanently eliminated the X-waiver requirement, any licensed prescriber can prescribe Suboxone via telehealth in most states. The DEA also extended COVID-era telehealth flexibilities through at least 2025, allowing virtual Suboxone induction without a prior in-person visit. Several specialty platforms — Bicycle Health, Ophelia, Workit Health, Boulder Care — offer Medicaid-accepting telehealth Suboxone treatment. Telehealth has dramatically expanded access in rural and underserved areas with no nearby OBOT physicians.

About Buprenorphine (Suboxone)

Buprenorphine is classified as a partial opioid agonist, meaning it activates opioid receptors in the brain but to a much lesser degree than full agonists such as heroin, fentanyl, or oxycodone. This partial activation suppresses withdrawal symptoms and reduces cravings without producing dangerous respiratory depression or intense euphoria. Buprenorphine also has an unusually high binding affinity for the mu-opioid receptor, effectively blocking other opioids from attaching — providing a protective effect against relapse-related overdose.

How Buprenorphine Works

One of the defining features of buprenorphine is its ceiling effect — after a certain dose threshold, increasing the amount does not produce additional opioid effects. This dramatically reduces the risk of fatal overdose compared to methadone or illicit opioids. The ceiling effect, combined with its long duration of action (24 to 72 hours), makes buprenorphine one of the safest and most effective tools in medication-assisted treatment (MAT). Approved by the FDA in 2002, buprenorphine was a breakthrough because it could be prescribed in outpatient settings rather than requiring daily clinic visits.

Buprenorphine Brand Comparison: Suboxone, Subutex, Sublocade, Zubsolv, Brixadi

Buprenorphine is available under several FDA-approved brand names, each with distinct formulations, dosing schedules, and clinical use cases. The comparison below highlights the key differences:

BrandActive ingredientFormFrequencySettingFDA yearBest for
SuboxoneBuprenorphine + naloxoneSublingual film / tabletDailyOBOT, telehealth, retail pharmacy2002Most prescribed; naloxone deters injection misuse
SubutexBuprenorphine (alone)Sublingual tabletDailyOBOT2002Pregnancy; documented naloxone sensitivity
SublocadeBuprenorphine extended-releaseSubcutaneous injection (ATRIGEL depot)MonthlyClinic-administered2017No daily dosing; eliminates diversion risk
ZubsolvBuprenorphine + naloxoneSublingual tablet (higher bioavailability)DailyOBOT2013Faster dissolution; mint flavor; lower mg/dose
BrixadiBuprenorphine extended-releaseSubcutaneous injectionWeekly or monthlyClinic2023Newer alternative to Sublocade; weekly option for induction

All five medications are Schedule III controlled substances and equivalent in clinical efficacy at appropriate doses. The choice depends on adherence patterns, lifestyle, insurance coverage, and clinical context (e.g., pregnancy, prior injection use, daily-dosing burden). Many patients begin on sublingual Suboxone for stabilization and transition to monthly Sublocade or weekly Brixadi after sustained recovery.

Buprenorphine Side Effects

Common buprenorphine side effects include:

  • Headache and dizziness
  • Nausea and vomiting, especially during induction
  • Constipation and insomnia
  • Excessive sweating
  • Mouth numbness or oral discomfort from sublingual formulations

More serious side effects may include respiratory depression (particularly when combined with benzodiazepines or alcohol), liver problems, and allergic reactions. For most patients, side effects are mild and resolve within one to two weeks. The benefits in preventing relapse and overdose death significantly outweigh the risks.

Buprenorphine Dosage and Induction

Treatment begins with an induction phase where the patient must be in mild to moderate opioid withdrawal. Common induction doses range from 2 mg to 8 mg on the first day, with increases over the following days. Most patients stabilize on 8 mg to 24 mg per day, with 16 mg being the most commonly prescribed dose. Research suggests doses of 16 mg or higher are associated with better retention and outcomes. Dosage should always be adjusted under medical supervision.

Buprenorphine/Naloxone Combination

Many buprenorphine formulations include naloxone as an abuse deterrent. When taken sublingually as directed, naloxone has very low bioavailability and produces no clinical effect. However, if someone attempts to inject the medication, the naloxone component becomes fully active and triggers severe withdrawal. This design discourages injection misuse while having no impact on patients who take the medication correctly. The combination is the standard first-line formulation for opioid addiction treatment.

Suboxone: Sublingual Buprenorphine

Suboxone is the most recognized brand name for buprenorphine-naloxone and is most commonly dispensed as a sublingual film (Suboxone strips) that dissolves under the tongue. Suboxone has transformed opioid treatment by enabling millions of patients to receive effective pharmacotherapy in outpatient settings without the daily clinic visits required by methadone programs.

Suboxone Side Effects

Commonly reported Suboxone side effects include headache, nausea, tongue or mouth irritation, constipation, insomnia, sweating, and decreased libido. The sublingual film can cause irritation or small sores inside the mouth — rotating placement between under the tongue and against the cheek helps minimize this. Patients should not eat, drink, or smoke while the film is dissolving.

Suboxone Strips: Film vs. Tablet

Suboxone strips (sublingual film) have largely replaced the original tablet form. The film dissolves more quickly (two to four minutes), provides more consistent absorption, and is harder to divert due to individual foil packaging. Generic buprenorphine-naloxone tablets are often less expensive and may be preferred for cost reasons. Both are therapeutically equivalent when taken as prescribed.

Suboxone Treatment Programs

Comprehensive Suboxone treatment typically includes three phases:

  • Induction: Initial dosing under medical supervision, requiring the patient to be in early withdrawal
  • Stabilization: Dose adjustment until cravings and withdrawal are minimal, usually one to two months
  • Maintenance: Stable dosing for an extended period — often a year or longer — combined with counseling and behavioral therapy

Evidence consistently shows that longer treatment durations are associated with better outcomes. Most addiction medicine experts recommend a minimum of one to two years of maintenance therapy.

Find a Suboxone Clinic Near You — OBOT & Telehealth Options

Finding a Suboxone clinic has become significantly easier since the federal government eliminated the X-waiver requirement in January 2023, meaning any provider with a standard DEA license can now prescribe Suboxone. Patients can search SAMHSA's treatment locator at findtreatment.gov or use our directory to locate nearby facilities that offer buprenorphine-based treatment.

Suboxone Doctors Near Me

Beyond SAMHSA's locator, many state health departments maintain directories of addiction treatment providers. Telehealth has dramatically expanded access — several platforms now offer virtual Suboxone consultations, which is especially valuable for patients in rural areas. When selecting a provider, look for those offering comprehensive treatment including counseling, not just medication prescriptions.

Suboxone Withdrawal and Tapering

Suboxone withdrawal can include muscle aches, anxiety, insomnia, nausea, sweating, and intense opioid cravings. A gradual, medically supervised taper is recommended — typically reducing the dose by 10 to 25 percent every one to four weeks. Slower tapers over several months produce fewer symptoms and lower relapse rates. There is no medically mandated time limit for Suboxone treatment, and many patients benefit from indefinite maintenance.

Suboxone vs Methadone

Suboxone can be prescribed in office settings and taken at home, carries lower overdose risk due to its ceiling effect, and offers greater scheduling flexibility. Methadone is a full agonist that may be more effective for severe, long-standing dependence but must be dispensed at licensed clinics with daily visits. Neither is inherently superior — the best choice keeps the patient in treatment. Some patients may also benefit from naltrexone, a non-opioid alternative.

Sublocade: Monthly Buprenorphine Injection

Sublocade delivers buprenorphine as a once-monthly subcutaneous injection in the abdominal area using the ATRIGEL delivery system, which forms a solid biodegradable depot that slowly releases medication. Patients must first stabilize on sublingual buprenorphine (8 mg+ daily) for at least seven days. Treatment typically begins with two 300 mg injections, followed by maintenance on 300 mg or 100 mg. Sublocade eliminates concerns about daily adherence, missed doses, and medication diversion.

Sublocade Side Effects

The most common Sublocade side effects are injection-site reactions (pain, itching, redness, or a noticeable lump), nausea, constipation, headache, and fatigue. The injection-site lump is normal and gradually diminishes as medication is absorbed. Patients should avoid rubbing or massaging the site. Elevated liver enzymes may also occur but are usually mild and transient.

Subutex: Buprenorphine Without Naloxone

Subutex was the original brand-name buprenorphine product. While the brand has been discontinued, generic buprenorphine-only tablets remain available. Buprenorphine monotherapy is typically reserved for pregnant patients (to avoid naloxone exposure to the fetus), patients with documented naloxone sensitivity, or sometimes during the induction phase before transitioning to the combination product.

Subutex vs Suboxone

The primary difference is the absence of naloxone in Subutex. Because Subutex lacks the abuse-deterrent naloxone component, it may carry slightly higher diversion risk, and many insurance formularies prioritize the combination as the default. Current clinical guidelines favor buprenorphine-only formulations primarily for pregnancy and naloxone sensitivity.

Zubsolv: Alternative Buprenorphine Brand

Zubsolv is a buprenorphine-naloxone sublingual tablet featuring a mint flavor and faster dissolution (under two minutes). Due to enhanced bioavailability, Zubsolv uses different dose strengths — a 5.7 mg/1.4 mg tablet equals a Suboxone 8 mg/2 mg dose. Zubsolv is available in multiple strengths for flexible dosing during both induction and maintenance.

Buprenorphine resources:

Find Buprenorphine (Suboxone) by State

Browse buprenorphine (suboxone) programs in states with the most treatment options.

Explore Related Options

Related conditions, treatment approaches, and levels of care.

Medically Reviewed Updated August 2026

Reviewed by licensed addiction specialists. Information reflects current clinical guidance.

Sources:SAMHSA·NIDA·CDC

Need immediate help? Call SAMHSA: 1-800-662-4357 (24/7, free)