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Medically Reviewed Content
Updated: July 2026
Sources: SAMHSA, NIDA

Suboxone Clinic Near You: Buprenorphine Treatment for Opioid Addiction

Find a Suboxone clinic near you. Buprenorphine — sold under brand names Suboxone, Sublocade, Subutex, Zubsolv, and Brixadi — is the most-prescribed MAT for opioid use disorder. It is a partial mu-opioid agonist with a ceiling effect that dramatically reduces overdose risk vs. methadone. After the MAT Act of 2023 eliminated the X-waiver requirement, any licensed prescriber can prescribe buprenorphine in office-based settings (OBOT), via telehealth, or at retail pharmacies. Buprenorphine is a Schedule III controlled substance and is covered by Medicaid in all 50 states.

Found 7,145 treatment centers offering buprenorphine (suboxone) across the United States.

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Ascendant New York
New York, NY

Ascendant New York, located in New York, NY, provides a full range of services for addiction recovery, including detox and therapies for substance abuse. The center features 24/7 residential care and various short-term residential options, creating a nurturing space for individuals seeking to recover. Using techniques such as 12-step programs, anger management, and cognitive behavioral strategies, the treatment plans are customized to meet the unique needs of each person. Ascendant New York caters to adults and young adults of all genders, emphasizing a tailored approach and a commitment to delivering high-quality care aimed at helping individuals attain enduring sobriety.

Ascendant NY
New York, NY

Ascendant NY, located in New York, NY, provides focused substance use rehabilitation via its residential programs. Prioritizing 12-step strategies, anger management techniques, and cognitive behavioral therapy, this facility caters to both adults and young adults with customized treatment plans. With an emphasis on personalized care, Ascendant NY delivers quality support for clients of all genders. The center offers both short-term and round-the-clock residential care, ensuring immersive assistance in a well-organized setting. By integrating proven methodologies with individualized attention, Ascendant NY distinguishes itself as a thorough rehabilitation center committed to aiding individuals in their journey to recovery from addiction.

Ascension Eastwood Behavioral Health

Ascension Eastwood Behavioral Health, located in Southfield, MI, delivers specialized services for those in need of detox and treatment for substance use disorders. The facility offers customized treatment plans for adults grappling with both substance use disorders and significant mental health issues, as well as for children experiencing severe emotional difficulties. With options including residential detox, continuous residential care, and short-term stays, the center provides 24/7 assistance to its clients. Employing methods like 12-step programs, cognitive behavioral therapy, and brief interventions, it emphasizes personalized care. Ascension Eastwood Behavioral Health serves a diverse range of individuals, including adult men, seniors, and young adults, ensuring excellent treatment that supports sustainable recovery with a focus on individualized attention.

Ascension Saint Vincent

Ascension Saint Vincent, located in Anderson, IN, provides a wide range of services for those seeking help with addiction. Catering to adults and older individuals, this center features inpatient detoxification and treatment specifically for substance use disorders, along with any accompanying mental health issues. The facility has unique programs designed for different demographics, including adolescents, men, and women. Utilizing methods such as 12-step support, anger management strategies, and concise interventions, Ascension Saint Vincent prioritizes personalized treatment. Both male and female clients benefit from specialized assistance in a nurturing environment. Committed to high standards of care, this center aims to support individuals on their journey to sustained recovery.

Ascent Recovery Solutions

Ascent Recovery Solutions in Simpsonville, SC, delivers extensive outpatient services for detoxification and the management of substance use disorders, catering to both adults and younger adults. This facility excels in offering guidance through 12-step programs, techniques for managing anger, and brief, impactful interventions to foster recovery. They provide customized treatment plans for active military members, as well as for adult men and women, ensuring gender-specific support tailored to individual requirements. Ascent Recovery Solutions prioritizes high-quality care and individualized approaches, cultivating a nurturing atmosphere for those striving to conquer addiction. For any individual, regardless of gender, seeking proven rehabilitation, Ascent Recovery Solutions is committed to facilitating enduring recovery.

Asheville Comprehensive Treatment Ctr

Asheville Comprehensive Treatment Ctr located in Asheville, NC, specializes in outpatient care for individuals struggling with substance use issues, including both adults and young adults. The center offers programs incorporating methadone, buprenorphine, and naltrexone, alongside standard outpatient services. Its methodology is rooted in evidence-based practices, integrating techniques such as brief interventions, cognitive behavioral therapy, and motivational incentives. The facility also includes specialized programs for clients involved in the criminal justice system and for women who are pregnant or in the postpartum phase. Committed to personalized care, this center supports male and female clients alike, fostering a nurturing and inclusive atmosphere for those pursuing recovery from addiction.

Ashley Inc
Bel Air, MD

Situated in Bel Air, Maryland, Ashley Inc provides extensive addiction recovery solutions for adults and adolescents. The center excels in detox and substance abuse treatment, delivering intensive outpatient, outpatient, and day treatment options. Emphasizing 12-step facilitation, anger control, and brief intervention strategies, Ashley Inc customizes its offerings to suit each person's distinct requirements. Distinctive services include targeted programs for individuals involved with the criminal justice system. Catering to both men and women, this establishment guarantees excellent care and assistance for individuals on their journey to overcome addiction.

Ascension Brighton Center for Recovery

Ascension Brighton Center for Recovery in Brighton, MI, provides extensive substance abuse treatment for adults and adolescents. Services include medically supervised detox and inpatient care, complemented by transitional living arrangements. Emphasizing 12-step integration, emotional regulation, and cognitive restructuring, the center addresses individuals facing concurrent mental health and addiction challenges. Both men and women are accepted, fostering a nurturing and welcoming atmosphere. Ascension Brighton Center for Recovery is committed to offering superior treatment and tailored plans to guide individuals toward lasting sobriety.

Ashley Addiction Treatment

Ashley Addiction Treatment, situated in Elkton, MD, delivers a full spectrum of care for those pursuing freedom from addiction. Their offerings include medically supervised detoxification and robust outpatient therapy, employing proven methods like 12-step integration, cognitive behavioral therapy, and emotional regulation training. Ashley distinguishes itself with tailored programs designed for adult men, adult women, and individuals impacted by domestic abuse, reflecting a commitment to serving a varied clientele. Both adult and adolescent patients have access to outpatient services and partial hospitalization programs. The center's dedication to personalized treatment plans and therapies backed by research guarantees exceptional support for everyone in their care.

Ascensa Health
Atlanta, GA

Situated in Atlanta, GA, Ascensa Health specializes in long-term residential rehabilitation for adults facing substance abuse and serious mental health disorders. This facility is particularly attentive to the needs of adult women, including those who have experienced intimate partner violence, domestic abuse, and sexual trauma. Ascensa Health emphasizes approaches such as 12-step facilitation, anger management, and brief interventions, serving female adults, seniors, and young adults in their pursuit of thorough and empathetic rehabilitation solutions. The center’s commitment to personalized treatment and exceptional care positions it as a leading option for individuals seeking specialized assistance for their substance use and mental health challenges.

Ascensa Health
Atlanta, GA

Situated in Atlanta, GA, Ascensa Health is a dedicated rehabilitation facility that provides extended residential and around-the-clock support for adult males in need of substance use treatment. The center emphasizes customized care, employing proven methodologies such as 12-step programs, cognitive behavioral therapy, and contingency management. Notably, Ascensa Health prioritizes the unique needs of clients who have faced intimate partner violence, domestic violence, and sexual trauma. Designed for adult men, including seniors and young adults, this center fosters a secure and nurturing atmosphere. With a strong focus on delivering high-quality care, Ascensa Health has established itself as a reliable option for those seeking thorough and impactful rehabilitation services.

Ascensa Health
Atlanta, GA

Ascensa Health in Atlanta, GA, delivers a full spectrum of addiction recovery solutions, encompassing medically supervised detox and ongoing treatment for substance dependence. The center features tailored programs designed for adult men, adult women, and individuals who have faced domestic abuse, ensuring personalized support for each client's unique circumstances. Employing evidence-based strategies like 12-step integration, cognitive behavioral techniques, and relapse prevention planning, Ascensa Health facilitates a complete and successful healing process. Their offerings include extended residential stays, detox in a residential setting, and round-the-clock residential care, available to adults and young adults of any gender. Discover exceptional care and encouragement at Ascensa Health as you embark on your path to lasting sobriety.

Ascensa Health
Atlanta, GA

Ascensa Health, located in Atlanta, GA, provides extensive treatment for substance use, specifically designed for women, seniors, and young adults. This center excels in long-term and around-the-clock residential care, offering personalized attention through research-backed methods like 12-step programs, cognitive behavioral therapy, and contingency management. Distinctive initiatives are available for adult women, as well as individuals healing from intimate partner violence, domestic abuse, and sexual trauma. Committed to high-quality, individualized care, Ascensa Health strives to support clients in attaining sustainable recovery.

Ascensa Health
Atlanta, GA

Ascensa Health, located in Atlanta, GA, provides a wide range of substance use rehabilitation services, including intensive outpatient programs, daytime outpatient treatment, and partial hospitalization options for both adults and young adults. The center specializes in various therapeutic approaches such as 12-step facilitation, cognitive behavioral therapy, and contingency management, offering customized support for both men and women, including those coping with intimate partner or domestic violence experiences. By emphasizing gender-specific requirements, Ascensa Health is dedicated to delivering effective care and assistance for individuals on their path to recovery from addiction.

Ascension All Saints

Ascension All Saints in Racine, WI, delivers exceptional rehabilitation care. They provide inpatient medical detoxification and comprehensive treatment for substance use disorders, alongside specialized programs for adults with co-occurring mental health conditions and children experiencing emotional difficulties. Their approach incorporates evidence-based therapies such as anger management, brief intervention, and cognitive behavioral therapy. The center features distinct programs designed for adult men, women, and individuals who have endured trauma. Their services are inclusive, catering to adults and seniors across all genders. Ascension All Saints is recognized for its thorough treatment plans and empathetic support for those pursuing healing from addiction and mental health concerns.

Ascend Recovery
American Fork, UT

Ascend Recovery, located in American Fork, UT, delivers a complete spectrum of care for adults and adolescents struggling with addiction and coexisting mental health concerns. Their offerings include intensive outpatient, extended residential, and outpatient services, all grounded in proven therapeutic methods like 12-step facilitation, anger management, and brief intervention. Tailored programs are available for adult men and women, as well as individuals with a history of sexual abuse. Ascend Recovery prioritizes personalized treatment plans within a nurturing setting for all clients on their journey to wellness.

Ascend Recovery
American Fork, UT

Ascend Recovery, located in American Fork, UT, delivers extensive treatment solutions for adults and young adults grappling with substance abuse and related mental health conditions. Their specialized care extends to those with histories of sexual trauma, offering intensive outpatient, extended residential stays, and regular outpatient therapy. Employing methods like 12-step integration, emotional regulation techniques, and short-term counseling, Ascend Recovery serves all genders. The facility prioritizes personalized care and targeted programs for adult men, adult women, and distinct age demographics, guaranteeing effective treatment designed for individual requirements.

Ascend Recovery
Salt Lake City, UT

Ascend Recovery in Salt Lake City, UT, delivers a complete spectrum of healing programs. The facility offers intensive outpatient, day treatment, and partial hospitalization for adults and young adults facing addiction and co-occurring psychological health challenges. Emphasizing 12-step principles, emotional regulation techniques, and brief counseling, this establishment serves adult men and women, along with individuals with a history of sexual trauma. Providing options for transitional living and sober residences, Ascend Recovery cultivates a nurturing atmosphere for those embarking on their healing journey. Featuring tailored initiatives for various age brackets and sexes, the center provides excellent support to address varied requirements.

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Ascension Illinois Presence Behavioral located in Palos Heights, IL, provides targeted treatment programs for substance use, serving both adults and teenagers. This facility offers intensive outpatient therapy, standard outpatient services, as well as outpatient treatment options involving methadone, buprenorphine, or naltrexone. Emphasizing 12-step facilitation, anger management techniques, and cognitive behavioral therapy, the center prioritizes personalized and thorough care. A standout feature is its specialized program for adolescents, catering to their distinct requirements in a nurturing setting. The center welcomes clients of all genders, ensuring high-quality, individualized support throughout their recovery journey.

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Ascension Illinois Presence Behavioral in Westchester, IL, is dedicated to assisting adults and young adults who are navigating the challenges of substance abuse and coexisting mental health disorders. The facility offers robust intensive outpatient and outpatient treatment tracks, incorporating medication-assisted treatment options such as methadone, buprenorphine, or naltrexone. Employing scientifically validated methods like 12-step facilitation, anger management techniques, and brief intervention strategies, Ascension Illinois Presence Behavioral serves a diverse clientele, accommodating both men and women. A particular emphasis is placed on supporting individuals involved in the criminal justice and forensic systems, ensuring a holistic recovery journey within a nurturing setting. The center's dedication to high standards and personalized care plans positions Ascension Illinois Presence Behavioral as a significant provider of addiction recovery services.

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Ashby Behavioral Health LLC, located in Quincy, MA, provides a wide range of services for substance use disorders and also addresses significant mental health challenges in adults and emotional issues in children. The facility delivers intensive outpatient programs, general outpatient services, and day treatment alternatives. Utilizing customized strategies such as 12-step support, anger management techniques, and brief interventions, they serve both adult and young adult populations of all genders. Additionally, programs specifically designed for active duty military personnel, as well as separate services for adult men and women, ensure personalized attention. Ashby Behavioral Health LLC is committed to offering high-quality, evidence-based care to assist individuals on their path to recovery.

Frequently Asked Questions

What is buprenorphine and how does it treat opioid addiction?
Buprenorphine is a partial opioid agonist medication approved by the FDA for treating opioid use disorder. It binds to the same receptors as heroin and fentanyl but produces a much weaker effect, reducing cravings and withdrawal symptoms without causing intense euphoria. Buprenorphine has a ceiling effect, meaning its opioid effects plateau at moderate doses, making it safer than methadone in terms of overdose risk.
What is the difference between Suboxone and Subutex?
Suboxone contains two active ingredients — buprenorphine and naloxone — while Subutex contains only buprenorphine without naloxone. The naloxone in Suboxone is included as an abuse deterrent; it remains inactive when taken sublingually as prescribed but triggers withdrawal if the medication is injected. Subutex is generally reserved for patients who cannot tolerate naloxone, such as pregnant women.
What is a Sublocade injection and how does it work?
Sublocade is a once-monthly injectable form of buprenorphine administered as a subcutaneous injection in the abdominal area. After injection, the medication forms a solid deposit under the skin that slowly releases buprenorphine over the course of a month. This eliminates daily dosing and removes the possibility of missed doses or medication diversion.
What are the common side effects of Suboxone?
Common Suboxone side effects include headache, nausea, constipation, insomnia, sweating, and mouth numbness or pain from sublingual administration. Some patients also experience dizziness, drowsiness, and blurred vision, particularly when starting treatment. Most side effects diminish within the first few weeks as the body adjusts. Patients should report difficulty breathing or signs of allergic reaction immediately.
What happens during Suboxone withdrawal?
Suboxone withdrawal occurs when a patient stops taking the medication abruptly after prolonged use, with symptoms including muscle aches, anxiety, insomnia, nausea, and irritability. A medically supervised taper is strongly recommended, typically reducing the dose by small increments over weeks or months. The risk of opioid relapse is significantly higher during unsupervised discontinuation.
How does Suboxone compare to methadone?
Suboxone and methadone are both effective for opioid use disorder but differ in key ways. Methadone is a full opioid agonist dispensed daily at licensed clinics, while Suboxone is a partial agonist that can be prescribed by qualified physicians and taken at home. Suboxone carries a lower overdose risk due to its ceiling effect and offers greater convenience, though methadone may be more appropriate for patients with severe, long-standing dependence.
How can I find a Suboxone clinic or doctor near me?
The most reliable way to find a Suboxone provider is through SAMHSA's online treatment locator at findtreatment.gov, which allows you to search by location and filter for buprenorphine providers. Many primary care offices, addiction treatment centers, and telehealth platforms now offer Suboxone prescriptions following the elimination of the federal X-waiver requirement in early 2023.
What is Zubsolv and how is it different from Suboxone?
Zubsolv is a brand-name buprenorphine and naloxone sublingual tablet that features a mint flavor and dissolves faster under the tongue than other options. Due to its higher bioavailability, Zubsolv uses different dosing strengths — a Zubsolv 5.7 mg/1.4 mg tablet is considered equivalent to a Suboxone 8 mg/2 mg dose. Patients switching between products should work closely with their prescriber for correct dose conversion.
Does Medicaid cover Suboxone treatment?
Yes — Medicaid covers buprenorphine (including Suboxone, Sublocade, Subutex, Zubsolv, and Brixadi) for opioid use disorder in all 50 states, as required by the SUPPORT Act of 2018. Medicaid is the largest single payer for MAT in the US. Coverage details vary by state — some require prior authorization or limit certain formulations. Many OBOT clinics accept Medicaid directly; telehealth Suboxone providers also bill Medicaid in most states. Bring your Medicaid card to your intake appointment.
Can I get Suboxone through telehealth?
Yes. After the MAT Act of 2023 permanently eliminated the X-waiver requirement, any licensed prescriber can prescribe Suboxone via telehealth in most states. The DEA also extended COVID-era telehealth flexibilities through at least 2025, allowing virtual Suboxone induction without a prior in-person visit. Several specialty platforms — Bicycle Health, Ophelia, Workit Health, Boulder Care — offer Medicaid-accepting telehealth Suboxone treatment. Telehealth has dramatically expanded access in rural and underserved areas with no nearby OBOT physicians.

About Buprenorphine (Suboxone)

Buprenorphine is classified as a partial opioid agonist, meaning it activates opioid receptors in the brain but to a much lesser degree than full agonists such as heroin, fentanyl, or oxycodone. This partial activation suppresses withdrawal symptoms and reduces cravings without producing dangerous respiratory depression or intense euphoria. Buprenorphine also has an unusually high binding affinity for the mu-opioid receptor, effectively blocking other opioids from attaching — providing a protective effect against relapse-related overdose.

How Buprenorphine Works

One of the defining features of buprenorphine is its ceiling effect — after a certain dose threshold, increasing the amount does not produce additional opioid effects. This dramatically reduces the risk of fatal overdose compared to methadone or illicit opioids. The ceiling effect, combined with its long duration of action (24 to 72 hours), makes buprenorphine one of the safest and most effective tools in medication-assisted treatment (MAT). Approved by the FDA in 2002, buprenorphine was a breakthrough because it could be prescribed in outpatient settings rather than requiring daily clinic visits.

Buprenorphine Brand Comparison: Suboxone, Subutex, Sublocade, Zubsolv, Brixadi

Buprenorphine is available under several FDA-approved brand names, each with distinct formulations, dosing schedules, and clinical use cases. The comparison below highlights the key differences:

BrandActive ingredientFormFrequencySettingFDA yearBest for
SuboxoneBuprenorphine + naloxoneSublingual film / tabletDailyOBOT, telehealth, retail pharmacy2002Most prescribed; naloxone deters injection misuse
SubutexBuprenorphine (alone)Sublingual tabletDailyOBOT2002Pregnancy; documented naloxone sensitivity
SublocadeBuprenorphine extended-releaseSubcutaneous injection (ATRIGEL depot)MonthlyClinic-administered2017No daily dosing; eliminates diversion risk
ZubsolvBuprenorphine + naloxoneSublingual tablet (higher bioavailability)DailyOBOT2013Faster dissolution; mint flavor; lower mg/dose
BrixadiBuprenorphine extended-releaseSubcutaneous injectionWeekly or monthlyClinic2023Newer alternative to Sublocade; weekly option for induction

All five medications are Schedule III controlled substances and equivalent in clinical efficacy at appropriate doses. The choice depends on adherence patterns, lifestyle, insurance coverage, and clinical context (e.g., pregnancy, prior injection use, daily-dosing burden). Many patients begin on sublingual Suboxone for stabilization and transition to monthly Sublocade or weekly Brixadi after sustained recovery.

Buprenorphine Side Effects

Common buprenorphine side effects include:

  • Headache and dizziness
  • Nausea and vomiting, especially during induction
  • Constipation and insomnia
  • Excessive sweating
  • Mouth numbness or oral discomfort from sublingual formulations

More serious side effects may include respiratory depression (particularly when combined with benzodiazepines or alcohol), liver problems, and allergic reactions. For most patients, side effects are mild and resolve within one to two weeks. The benefits in preventing relapse and overdose death significantly outweigh the risks.

Buprenorphine Dosage and Induction

Treatment begins with an induction phase where the patient must be in mild to moderate opioid withdrawal. Common induction doses range from 2 mg to 8 mg on the first day, with increases over the following days. Most patients stabilize on 8 mg to 24 mg per day, with 16 mg being the most commonly prescribed dose. Research suggests doses of 16 mg or higher are associated with better retention and outcomes. Dosage should always be adjusted under medical supervision.

Buprenorphine/Naloxone Combination

Many buprenorphine formulations include naloxone as an abuse deterrent. When taken sublingually as directed, naloxone has very low bioavailability and produces no clinical effect. However, if someone attempts to inject the medication, the naloxone component becomes fully active and triggers severe withdrawal. This design discourages injection misuse while having no impact on patients who take the medication correctly. The combination is the standard first-line formulation for opioid addiction treatment.

Suboxone: Sublingual Buprenorphine

Suboxone is the most recognized brand name for buprenorphine-naloxone and is most commonly dispensed as a sublingual film (Suboxone strips) that dissolves under the tongue. Suboxone has transformed opioid treatment by enabling millions of patients to receive effective pharmacotherapy in outpatient settings without the daily clinic visits required by methadone programs.

Suboxone Side Effects

Commonly reported Suboxone side effects include headache, nausea, tongue or mouth irritation, constipation, insomnia, sweating, and decreased libido. The sublingual film can cause irritation or small sores inside the mouth — rotating placement between under the tongue and against the cheek helps minimize this. Patients should not eat, drink, or smoke while the film is dissolving.

Suboxone Strips: Film vs. Tablet

Suboxone strips (sublingual film) have largely replaced the original tablet form. The film dissolves more quickly (two to four minutes), provides more consistent absorption, and is harder to divert due to individual foil packaging. Generic buprenorphine-naloxone tablets are often less expensive and may be preferred for cost reasons. Both are therapeutically equivalent when taken as prescribed.

Suboxone Treatment Programs

Comprehensive Suboxone treatment typically includes three phases:

  • Induction: Initial dosing under medical supervision, requiring the patient to be in early withdrawal
  • Stabilization: Dose adjustment until cravings and withdrawal are minimal, usually one to two months
  • Maintenance: Stable dosing for an extended period — often a year or longer — combined with counseling and behavioral therapy

Evidence consistently shows that longer treatment durations are associated with better outcomes. Most addiction medicine experts recommend a minimum of one to two years of maintenance therapy.

Find a Suboxone Clinic Near You — OBOT & Telehealth Options

Finding a Suboxone clinic has become significantly easier since the federal government eliminated the X-waiver requirement in January 2023, meaning any provider with a standard DEA license can now prescribe Suboxone. Patients can search SAMHSA's treatment locator at findtreatment.gov or use our directory to locate nearby facilities that offer buprenorphine-based treatment.

Suboxone Doctors Near Me

Beyond SAMHSA's locator, many state health departments maintain directories of addiction treatment providers. Telehealth has dramatically expanded access — several platforms now offer virtual Suboxone consultations, which is especially valuable for patients in rural areas. When selecting a provider, look for those offering comprehensive treatment including counseling, not just medication prescriptions.

Suboxone Withdrawal and Tapering

Suboxone withdrawal can include muscle aches, anxiety, insomnia, nausea, sweating, and intense opioid cravings. A gradual, medically supervised taper is recommended — typically reducing the dose by 10 to 25 percent every one to four weeks. Slower tapers over several months produce fewer symptoms and lower relapse rates. There is no medically mandated time limit for Suboxone treatment, and many patients benefit from indefinite maintenance.

Suboxone vs Methadone

Suboxone can be prescribed in office settings and taken at home, carries lower overdose risk due to its ceiling effect, and offers greater scheduling flexibility. Methadone is a full agonist that may be more effective for severe, long-standing dependence but must be dispensed at licensed clinics with daily visits. Neither is inherently superior — the best choice keeps the patient in treatment. Some patients may also benefit from naltrexone, a non-opioid alternative.

Sublocade: Monthly Buprenorphine Injection

Sublocade delivers buprenorphine as a once-monthly subcutaneous injection in the abdominal area using the ATRIGEL delivery system, which forms a solid biodegradable depot that slowly releases medication. Patients must first stabilize on sublingual buprenorphine (8 mg+ daily) for at least seven days. Treatment typically begins with two 300 mg injections, followed by maintenance on 300 mg or 100 mg. Sublocade eliminates concerns about daily adherence, missed doses, and medication diversion.

Sublocade Side Effects

The most common Sublocade side effects are injection-site reactions (pain, itching, redness, or a noticeable lump), nausea, constipation, headache, and fatigue. The injection-site lump is normal and gradually diminishes as medication is absorbed. Patients should avoid rubbing or massaging the site. Elevated liver enzymes may also occur but are usually mild and transient.

Subutex: Buprenorphine Without Naloxone

Subutex was the original brand-name buprenorphine product. While the brand has been discontinued, generic buprenorphine-only tablets remain available. Buprenorphine monotherapy is typically reserved for pregnant patients (to avoid naloxone exposure to the fetus), patients with documented naloxone sensitivity, or sometimes during the induction phase before transitioning to the combination product.

Subutex vs Suboxone

The primary difference is the absence of naloxone in Subutex. Because Subutex lacks the abuse-deterrent naloxone component, it may carry slightly higher diversion risk, and many insurance formularies prioritize the combination as the default. Current clinical guidelines favor buprenorphine-only formulations primarily for pregnancy and naloxone sensitivity.

Zubsolv: Alternative Buprenorphine Brand

Zubsolv is a buprenorphine-naloxone sublingual tablet featuring a mint flavor and faster dissolution (under two minutes). Due to enhanced bioavailability, Zubsolv uses different dose strengths — a 5.7 mg/1.4 mg tablet equals a Suboxone 8 mg/2 mg dose. Zubsolv is available in multiple strengths for flexible dosing during both induction and maintenance.

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Medically Reviewed Updated July 2026

Reviewed by licensed addiction specialists. Information reflects current clinical guidance.

Sources:SAMHSA·NIDA·CDC

Need immediate help? Call SAMHSA: 1-800-662-4357 (24/7, free)