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Medically Reviewed Content
Updated: July 2026
Sources: SAMHSA, NIDA

Suboxone Clinic Near You: Buprenorphine Treatment for Opioid Addiction

Find a Suboxone clinic near you. Buprenorphine — sold under brand names Suboxone, Sublocade, Subutex, Zubsolv, and Brixadi — is the most-prescribed MAT for opioid use disorder. It is a partial mu-opioid agonist with a ceiling effect that dramatically reduces overdose risk vs. methadone. After the MAT Act of 2023 eliminated the X-waiver requirement, any licensed prescriber can prescribe buprenorphine in office-based settings (OBOT), via telehealth, or at retail pharmacies. Buprenorphine is a Schedule III controlled substance and is covered by Medicaid in all 50 states.

Found 7,145 treatment centers offering buprenorphine (suboxone) across the United States.

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Rushford Center Inc
Glastonbury, CT

Nestled in Glastonbury, CT, Rushford Center Inc is dedicated to providing comprehensive substance abuse treatment and support for those navigating dual diagnoses involving significant mental health challenges. This establishment offers a spectrum of care, including intensive outpatient, outpatient day treatment, and partial hospitalization programs designed for adults and young adults. Their approach integrates 12-step facilitation, cognitive behavioral therapy, and motivational interviewing, ensuring that programs at Rushford Center Inc are customized to the individual requirements of adult men and women, including those with a history of trauma. Through gender-specific programming, the center delivers tailored support for both male and female individuals, prioritizing effective, research-backed methods for recovery and wellness.

Rural Health Inc

Rural Health Inc, situated in Anna, IL, delivers extensive outpatient services for individuals battling substance use disorders. This facility is particularly adept at addressing co-occurring substance use and severe mental health challenges, employing customized therapeutic approaches such as cognitive behavioral therapy and motivational interviewing. Their specialized care extends to trauma survivors and those with dual diagnoses, accommodating both male and female patients. Available treatment modalities encompass outpatient medication management (methadone, buprenorphine, naltrexone) and standard outpatient counseling. Rural Health Inc is committed to providing superior and individualized rehabilitation solutions.

Rural Nevada Counseling

Situated in Yerington, NV, Rural Nevada Counseling provides a wide range of addiction recovery services for adults and older adults. This center focuses on treating substance use disorders and addresses dual conditions involving severe mental health problems in adults, as well as emotional challenges in children. With both intensive outpatient and standard outpatient services offered, the facility employs proven methodologies including 12-step facilitation, cognitive behavioral therapy, and short-term strategies. Special programs are designed for active military members, teenagers, and adult males. By delivering tailored care for both men and women, Rural Nevada Counseling aims to facilitate effective recovery journeys for individuals battling addiction.

Rushford Center Inc
Middletown, CT

Rushford Center Inc, situated in Middletown, CT, presents a wide array of treatment services targeting substance use for both adults and young adults. The center’s tailored programs effectively manage co-occurring substance use disorders along with significant mental health challenges in adults, and address serious emotional issues in children. Options include intensive outpatient treatment, outpatient services, and day treatment or partial hospitalization. By employing evidence-based methods such as 12-step facilitation, cognitive behavioral therapy, and motivational interviewing, Rushford Center Inc meets the specific needs of adult men, women, and individuals who have undergone trauma. Committed to providing quality care and personalized treatment, this center plays a crucial role in guiding individuals toward recovery.

Rushford Center Inc
Middletown, CT

Situated in Middletown, Connecticut, Rushford Center Inc delivers targeted treatment for substance use disorders among both adults and young adults who are also grappling with significant mental health challenges. The facility offers various levels of care, including intensive outpatient programs, outpatient day treatment, and partial hospitalization, employing methods such as 12-step support and anger management strategies. Additionally, Rushford Center Inc features specialized programs tailored for active military personnel, men, and women, addressing a wide array of specific requirements. Their commitment to high-quality care and personalized treatment plans establishes them as a leading option for individuals in need of thorough rehabilitation services.

Rushford Center Inc
Middletown, CT

Situated in Middletown, Connecticut, Rushford Center Inc delivers a wide array of detoxification and substance use treatment options. The center features intensive outpatient, outpatient, and day treatment programs that utilize methods such as anger management, brief intervention, and cognitive behavioral therapy. With tailored programs for active duty service members, as well as adult men and women, Rushford Center Inc serves a varied clientele. Committed to providing high-quality care, the center employs evidence-based practices to assist both adults and young adults of all genders in their recovery journey.

Russell E Blaisdell
Orangeburg, NY

The Russell E Blaisdell rehabilitation center in Orangeburg, NY, specializes in comprehensive care for adult males battling substance use disorders. This inpatient hospital provides crucial services for individuals with co-occurring substance use and severe mental health conditions. Their therapeutic approach incorporates 12-step facilitation, anger management techniques, and brief intervention strategies, specifically tailored for active duty military members, adult men, and survivors of intimate partner violence. The center is dedicated to delivering high-quality support and recovery services to adults across all age groups, including seniors and young adults.

Rutgers/UBHC
New Brunswick, NJ

Situated in New Brunswick, NJ, Rutgers/UBHC delivers extensive rehabilitation services aimed at adults and young adults facing challenges related to substance abuse and concurrent mental health issues. The center offers a range of programs including detoxification, intensive outpatient care, and standard outpatient options, employing evidence-based methodologies like cognitive behavioral therapy and anger management techniques. With a particular focus on supporting trauma survivors and individuals with legal issues, Rutgers/UBHC also provides outpatient treatment options using methadone, buprenorphine, and naltrexone. Committed to delivering high-quality care and personalized treatment plans, this facility supports both men and women in their quest for effective and compassionate addiction recovery.

Rylist Inc
Thousand Oaks, CA

Nestled in Thousand Oaks, California, Rylist Inc delivers exceptional addiction recovery programs. Their expertise includes detox and comprehensive substance use therapy, featuring extended stay residential housing, immediate detox services, and round-the-clock on-site assistance. Employing strategies like 12-step integration, emotional regulation training, and concise intervention methods, Rylist Inc serves adult men and women, encompassing active military members. Their services extend to programs designed for adults and adolescents of all genders, highlighting a commitment to thorough and personalized healing. For those pursuing proven, data-driven rehabilitation within a nurturing setting, Rylist Inc represents a premier option for embarking on your recovery path.

Rylist Inc
Thousand Oaks, CA

Situated in Thousand Oaks, CA, Rylist Inc delivers a variety of premium rehabilitation services aimed at individuals facing challenges with substance use and related mental health issues. This center offers both long-term and short-term, as well as 24-hour residential treatment programs designed for adults and young adults. Rylist Inc emphasizes 12-step facilitation, anger management, and brief intervention techniques. With specific programs available for active military personnel, adult men, and women, the center focuses on individualized care for every client. Committed to evidence-based methodologies, Rylist Inc supports clients of all genders in their recovery paths.

Rural Health Inc
Goreville, IL

Rural Health Inc, situated in Goreville, IL, provides extensive outpatient care for adults and young adults struggling with substance use. This center is particularly adept at addressing dual diagnoses, managing co-occurring substance use disorders and significant mental health conditions in adults, and emotional challenges in children. Employing approaches like cognitive behavioral therapy, motivational interviewing, and brief interventions, they deliver tailored support to both male and female patients. Rural Health Inc also offers specialized assistance to those with a history of trauma and individuals facing concurrent mental health concerns. Their comprehensive services include outpatient treatment with methadone/buprenorphine or naltrexone, integrated with ongoing outpatient support, promoting a well-rounded path to recovery.

Rural Health Inc
Dongola, IL

Rural Health Inc, situated in Dongola, IL, provides extensive support for individuals battling substance use disorders and those facing complex challenges with co-occurring mental health conditions. Their specialized programs cater to both adults and young people, offering outpatient options such as methadone and buprenorphine treatment alongside standard outpatient care. Employing proven methods like cognitive behavioral therapy and motivational interviewing, the center is distinguished by its dedicated approach to individuals with trauma histories and dual diagnoses. Rural Health Inc is committed to delivering high-quality, personalized care to foster sustained recovery for all clients, regardless of gender.

Rural Nevada Counseling
Silver Springs, NV

At its Silver Springs, NV location, Rural Nevada Counseling is dedicated to providing extensive support for substance abuse and tailored services for individuals facing the complexities of both substance use disorders and significant mental health challenges. They also address serious emotional disturbances in young people. The facility's treatment offerings include intensive outpatient, standard outpatient, and medication-assisted treatment options utilizing methadone, buprenorphine, or naltrexone. Employing therapeutic modalities such as 12-step facilitation, brief intervention, and cognitive behavioral therapy, this center is equipped to assist active military members, teenagers, and adult males. Rural Nevada Counseling extends its high-quality, individualized care to adults and older adults of any gender.

Rural Nevada Counseling

Situated in Fernley, NV, Rural Nevada Counseling delivers extensive treatment for substance use disorders alongside targeted care for those facing both substance use and significant mental health challenges. The center offers a variety of treatment modalities, including intensive outpatient, outpatient services, and medication-assisted options such as methadone, buprenorphine, or naltrexone. Emphasizing methods like 12-step facilitation, brief intervention, and cognitive behavioral therapy, this center customizes its programs to meet the needs of active military personnel, teenagers, and adult males. Catering to men and women of all ages, Rural Nevada Counseling provides high-quality, personalized care to assist individuals as they work towards recovery.

Rushford at Avon

Situated in Avon, CT, Rushford at Avon provides targeted care for individuals facing substance use challenges alongside co-existing mental health disorders in both adults and children. Emphasizing outpatient and intensive outpatient services, the center offers therapeutic methods such as 12-step programs, cognitive behavioral therapy, and motivational interviewing. Customized treatment plans are available for adult men, adult women, and those who have gone through traumatic experiences, ensuring individualized attention. Catering to adults and young adults of any gender, Rushford at Avon creates a supportive atmosphere for healing. If you or someone you know is in search of research-backed treatment delivered with empathy, this facility is committed to offering high-quality care aimed at fostering enduring recovery.

Rushford at Cheshire

Situated in Cheshire, CT, Rushford at Cheshire provides focused treatment for adults addressing substance use challenges alongside serious mental health conditions. Their outpatient and intensive outpatient programs utilize proven methods such as cognitive behavioral therapy and motivational interviewing. This center also offers customized programs designed for adult men and women, including those who have faced trauma. Emphasizing anger management and holistic care for both younger and adult clients, Rushford at Cheshire is dedicated to delivering quality rehabilitation services in a nurturing atmosphere for individuals in need in Connecticut.

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Metropolis, IL

Situated in Metropolis, IL, Rural Health Inc delivers an extensive variety of outpatient treatment services for individuals struggling with substance use, including both adults and young adults. The center specializes in addressing both substance use disorders and severe mental health conditions, employing evidence-based techniques such as cognitive behavioral therapy and motivational interviewing. Emphasizing trauma-informed care, Rural Health Inc is dedicated to assisting clients who have experienced trauma and those facing both mental health challenges and substance use issues. With programs designed separately for males and females, the center ensures that each individual receives a personalized treatment strategy. Clients looking for standard outpatient care or methadone/buprenorphine therapy can anticipate receiving exceptional support and quality care at Rural Health Inc.

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Situated in Vienna, IL, Rural Health Inc provides targeted outpatient services for individuals dealing with substance abuse, concurrent mental health issues, and those who have experienced trauma. Catering to both adults and young adults across all genders, this center utilizes a variety of evidence-supported methods such as cognitive behavioral therapy and motivational interviewing. Emphasizing personalized treatment, the facility is equipped to support clients needing consistent outpatient care, as well as those pursuing methadone, buprenorphine, or naltrexone therapies. Patients receive customized support and interventions aimed at addressing significant emotional challenges. Rural Health Inc is recognized for its exceptional, all-encompassing services that foster sustainable recovery and overall wellness.

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Located in Dayton, NV, Rural Nevada Counseling offers comprehensive substance use treatment and specialized care for co-occurring substance use and serious mental health illnesses in adults or serious emotional disturbances in children. With intensive outpatient, outpatient, and methadone/buprenorphine or naltrexone treatment options, the center utilizes 12-step facilitation, brief intervention, and cognitive behavioral therapy approaches. Tailored programs are available for active duty military, adolescents, and adult men. Serving adults and seniors of all genders, this facility provides quality care and support to help individuals on their path to recovery.

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Rushford Center Inc, situated in Meriden, CT, provides extensive services for individuals battling substance use disorders. They also offer expert support for those facing the dual challenges of addiction and serious mental health conditions. Their treatment options include intensive outpatient care, standard outpatient services, and medication-assisted treatment using methadone, buprenorphine, or naltrexone. Employing evidence-based strategies like anger management, cognitive behavioral therapy, and motivational interviewing, Rushford Center Inc assists adolescents and adults of all genders. The center is dedicated to crafting personalized recovery journeys that promote long-term sobriety and overall wellness.

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Thousand Oaks, CA

Rylist Inc, located in Thousand Oaks, CA, specializes in extensive rehabilitation programs for both adults and young adults facing challenges related to substance abuse and concurrent mental health disorders. The facility offers a range of services including intensive outpatient therapy, day treatment options, and partial hospitalization. Emphasizing methodologies such as 12-step programming, anger management, and brief intervention techniques, Rylist Inc addresses the specific requirements of active duty military members as well as men and women of various ages. Clients are provided with tailored support that is sensitive to their gender and age demographics. Rylist Inc is dedicated to offering exceptional, personalized care to aid clients in their recovery journey.

Frequently Asked Questions

What is buprenorphine and how does it treat opioid addiction?
Buprenorphine is a partial opioid agonist medication approved by the FDA for treating opioid use disorder. It binds to the same receptors as heroin and fentanyl but produces a much weaker effect, reducing cravings and withdrawal symptoms without causing intense euphoria. Buprenorphine has a ceiling effect, meaning its opioid effects plateau at moderate doses, making it safer than methadone in terms of overdose risk.
What is the difference between Suboxone and Subutex?
Suboxone contains two active ingredients — buprenorphine and naloxone — while Subutex contains only buprenorphine without naloxone. The naloxone in Suboxone is included as an abuse deterrent; it remains inactive when taken sublingually as prescribed but triggers withdrawal if the medication is injected. Subutex is generally reserved for patients who cannot tolerate naloxone, such as pregnant women.
What is a Sublocade injection and how does it work?
Sublocade is a once-monthly injectable form of buprenorphine administered as a subcutaneous injection in the abdominal area. After injection, the medication forms a solid deposit under the skin that slowly releases buprenorphine over the course of a month. This eliminates daily dosing and removes the possibility of missed doses or medication diversion.
What are the common side effects of Suboxone?
Common Suboxone side effects include headache, nausea, constipation, insomnia, sweating, and mouth numbness or pain from sublingual administration. Some patients also experience dizziness, drowsiness, and blurred vision, particularly when starting treatment. Most side effects diminish within the first few weeks as the body adjusts. Patients should report difficulty breathing or signs of allergic reaction immediately.
What happens during Suboxone withdrawal?
Suboxone withdrawal occurs when a patient stops taking the medication abruptly after prolonged use, with symptoms including muscle aches, anxiety, insomnia, nausea, and irritability. A medically supervised taper is strongly recommended, typically reducing the dose by small increments over weeks or months. The risk of opioid relapse is significantly higher during unsupervised discontinuation.
How does Suboxone compare to methadone?
Suboxone and methadone are both effective for opioid use disorder but differ in key ways. Methadone is a full opioid agonist dispensed daily at licensed clinics, while Suboxone is a partial agonist that can be prescribed by qualified physicians and taken at home. Suboxone carries a lower overdose risk due to its ceiling effect and offers greater convenience, though methadone may be more appropriate for patients with severe, long-standing dependence.
How can I find a Suboxone clinic or doctor near me?
The most reliable way to find a Suboxone provider is through SAMHSA's online treatment locator at findtreatment.gov, which allows you to search by location and filter for buprenorphine providers. Many primary care offices, addiction treatment centers, and telehealth platforms now offer Suboxone prescriptions following the elimination of the federal X-waiver requirement in early 2023.
What is Zubsolv and how is it different from Suboxone?
Zubsolv is a brand-name buprenorphine and naloxone sublingual tablet that features a mint flavor and dissolves faster under the tongue than other options. Due to its higher bioavailability, Zubsolv uses different dosing strengths — a Zubsolv 5.7 mg/1.4 mg tablet is considered equivalent to a Suboxone 8 mg/2 mg dose. Patients switching between products should work closely with their prescriber for correct dose conversion.
Does Medicaid cover Suboxone treatment?
Yes — Medicaid covers buprenorphine (including Suboxone, Sublocade, Subutex, Zubsolv, and Brixadi) for opioid use disorder in all 50 states, as required by the SUPPORT Act of 2018. Medicaid is the largest single payer for MAT in the US. Coverage details vary by state — some require prior authorization or limit certain formulations. Many OBOT clinics accept Medicaid directly; telehealth Suboxone providers also bill Medicaid in most states. Bring your Medicaid card to your intake appointment.
Can I get Suboxone through telehealth?
Yes. After the MAT Act of 2023 permanently eliminated the X-waiver requirement, any licensed prescriber can prescribe Suboxone via telehealth in most states. The DEA also extended COVID-era telehealth flexibilities through at least 2025, allowing virtual Suboxone induction without a prior in-person visit. Several specialty platforms — Bicycle Health, Ophelia, Workit Health, Boulder Care — offer Medicaid-accepting telehealth Suboxone treatment. Telehealth has dramatically expanded access in rural and underserved areas with no nearby OBOT physicians.

About Buprenorphine (Suboxone)

Buprenorphine is classified as a partial opioid agonist, meaning it activates opioid receptors in the brain but to a much lesser degree than full agonists such as heroin, fentanyl, or oxycodone. This partial activation suppresses withdrawal symptoms and reduces cravings without producing dangerous respiratory depression or intense euphoria. Buprenorphine also has an unusually high binding affinity for the mu-opioid receptor, effectively blocking other opioids from attaching — providing a protective effect against relapse-related overdose.

How Buprenorphine Works

One of the defining features of buprenorphine is its ceiling effect — after a certain dose threshold, increasing the amount does not produce additional opioid effects. This dramatically reduces the risk of fatal overdose compared to methadone or illicit opioids. The ceiling effect, combined with its long duration of action (24 to 72 hours), makes buprenorphine one of the safest and most effective tools in medication-assisted treatment (MAT). Approved by the FDA in 2002, buprenorphine was a breakthrough because it could be prescribed in outpatient settings rather than requiring daily clinic visits.

Buprenorphine Brand Comparison: Suboxone, Subutex, Sublocade, Zubsolv, Brixadi

Buprenorphine is available under several FDA-approved brand names, each with distinct formulations, dosing schedules, and clinical use cases. The comparison below highlights the key differences:

BrandActive ingredientFormFrequencySettingFDA yearBest for
SuboxoneBuprenorphine + naloxoneSublingual film / tabletDailyOBOT, telehealth, retail pharmacy2002Most prescribed; naloxone deters injection misuse
SubutexBuprenorphine (alone)Sublingual tabletDailyOBOT2002Pregnancy; documented naloxone sensitivity
SublocadeBuprenorphine extended-releaseSubcutaneous injection (ATRIGEL depot)MonthlyClinic-administered2017No daily dosing; eliminates diversion risk
ZubsolvBuprenorphine + naloxoneSublingual tablet (higher bioavailability)DailyOBOT2013Faster dissolution; mint flavor; lower mg/dose
BrixadiBuprenorphine extended-releaseSubcutaneous injectionWeekly or monthlyClinic2023Newer alternative to Sublocade; weekly option for induction

All five medications are Schedule III controlled substances and equivalent in clinical efficacy at appropriate doses. The choice depends on adherence patterns, lifestyle, insurance coverage, and clinical context (e.g., pregnancy, prior injection use, daily-dosing burden). Many patients begin on sublingual Suboxone for stabilization and transition to monthly Sublocade or weekly Brixadi after sustained recovery.

Buprenorphine Side Effects

Common buprenorphine side effects include:

  • Headache and dizziness
  • Nausea and vomiting, especially during induction
  • Constipation and insomnia
  • Excessive sweating
  • Mouth numbness or oral discomfort from sublingual formulations

More serious side effects may include respiratory depression (particularly when combined with benzodiazepines or alcohol), liver problems, and allergic reactions. For most patients, side effects are mild and resolve within one to two weeks. The benefits in preventing relapse and overdose death significantly outweigh the risks.

Buprenorphine Dosage and Induction

Treatment begins with an induction phase where the patient must be in mild to moderate opioid withdrawal. Common induction doses range from 2 mg to 8 mg on the first day, with increases over the following days. Most patients stabilize on 8 mg to 24 mg per day, with 16 mg being the most commonly prescribed dose. Research suggests doses of 16 mg or higher are associated with better retention and outcomes. Dosage should always be adjusted under medical supervision.

Buprenorphine/Naloxone Combination

Many buprenorphine formulations include naloxone as an abuse deterrent. When taken sublingually as directed, naloxone has very low bioavailability and produces no clinical effect. However, if someone attempts to inject the medication, the naloxone component becomes fully active and triggers severe withdrawal. This design discourages injection misuse while having no impact on patients who take the medication correctly. The combination is the standard first-line formulation for opioid addiction treatment.

Suboxone: Sublingual Buprenorphine

Suboxone is the most recognized brand name for buprenorphine-naloxone and is most commonly dispensed as a sublingual film (Suboxone strips) that dissolves under the tongue. Suboxone has transformed opioid treatment by enabling millions of patients to receive effective pharmacotherapy in outpatient settings without the daily clinic visits required by methadone programs.

Suboxone Side Effects

Commonly reported Suboxone side effects include headache, nausea, tongue or mouth irritation, constipation, insomnia, sweating, and decreased libido. The sublingual film can cause irritation or small sores inside the mouth — rotating placement between under the tongue and against the cheek helps minimize this. Patients should not eat, drink, or smoke while the film is dissolving.

Suboxone Strips: Film vs. Tablet

Suboxone strips (sublingual film) have largely replaced the original tablet form. The film dissolves more quickly (two to four minutes), provides more consistent absorption, and is harder to divert due to individual foil packaging. Generic buprenorphine-naloxone tablets are often less expensive and may be preferred for cost reasons. Both are therapeutically equivalent when taken as prescribed.

Suboxone Treatment Programs

Comprehensive Suboxone treatment typically includes three phases:

  • Induction: Initial dosing under medical supervision, requiring the patient to be in early withdrawal
  • Stabilization: Dose adjustment until cravings and withdrawal are minimal, usually one to two months
  • Maintenance: Stable dosing for an extended period — often a year or longer — combined with counseling and behavioral therapy

Evidence consistently shows that longer treatment durations are associated with better outcomes. Most addiction medicine experts recommend a minimum of one to two years of maintenance therapy.

Find a Suboxone Clinic Near You — OBOT & Telehealth Options

Finding a Suboxone clinic has become significantly easier since the federal government eliminated the X-waiver requirement in January 2023, meaning any provider with a standard DEA license can now prescribe Suboxone. Patients can search SAMHSA's treatment locator at findtreatment.gov or use our directory to locate nearby facilities that offer buprenorphine-based treatment.

Suboxone Doctors Near Me

Beyond SAMHSA's locator, many state health departments maintain directories of addiction treatment providers. Telehealth has dramatically expanded access — several platforms now offer virtual Suboxone consultations, which is especially valuable for patients in rural areas. When selecting a provider, look for those offering comprehensive treatment including counseling, not just medication prescriptions.

Suboxone Withdrawal and Tapering

Suboxone withdrawal can include muscle aches, anxiety, insomnia, nausea, sweating, and intense opioid cravings. A gradual, medically supervised taper is recommended — typically reducing the dose by 10 to 25 percent every one to four weeks. Slower tapers over several months produce fewer symptoms and lower relapse rates. There is no medically mandated time limit for Suboxone treatment, and many patients benefit from indefinite maintenance.

Suboxone vs Methadone

Suboxone can be prescribed in office settings and taken at home, carries lower overdose risk due to its ceiling effect, and offers greater scheduling flexibility. Methadone is a full agonist that may be more effective for severe, long-standing dependence but must be dispensed at licensed clinics with daily visits. Neither is inherently superior — the best choice keeps the patient in treatment. Some patients may also benefit from naltrexone, a non-opioid alternative.

Sublocade: Monthly Buprenorphine Injection

Sublocade delivers buprenorphine as a once-monthly subcutaneous injection in the abdominal area using the ATRIGEL delivery system, which forms a solid biodegradable depot that slowly releases medication. Patients must first stabilize on sublingual buprenorphine (8 mg+ daily) for at least seven days. Treatment typically begins with two 300 mg injections, followed by maintenance on 300 mg or 100 mg. Sublocade eliminates concerns about daily adherence, missed doses, and medication diversion.

Sublocade Side Effects

The most common Sublocade side effects are injection-site reactions (pain, itching, redness, or a noticeable lump), nausea, constipation, headache, and fatigue. The injection-site lump is normal and gradually diminishes as medication is absorbed. Patients should avoid rubbing or massaging the site. Elevated liver enzymes may also occur but are usually mild and transient.

Subutex: Buprenorphine Without Naloxone

Subutex was the original brand-name buprenorphine product. While the brand has been discontinued, generic buprenorphine-only tablets remain available. Buprenorphine monotherapy is typically reserved for pregnant patients (to avoid naloxone exposure to the fetus), patients with documented naloxone sensitivity, or sometimes during the induction phase before transitioning to the combination product.

Subutex vs Suboxone

The primary difference is the absence of naloxone in Subutex. Because Subutex lacks the abuse-deterrent naloxone component, it may carry slightly higher diversion risk, and many insurance formularies prioritize the combination as the default. Current clinical guidelines favor buprenorphine-only formulations primarily for pregnancy and naloxone sensitivity.

Zubsolv: Alternative Buprenorphine Brand

Zubsolv is a buprenorphine-naloxone sublingual tablet featuring a mint flavor and faster dissolution (under two minutes). Due to enhanced bioavailability, Zubsolv uses different dose strengths — a 5.7 mg/1.4 mg tablet equals a Suboxone 8 mg/2 mg dose. Zubsolv is available in multiple strengths for flexible dosing during both induction and maintenance.

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Medically Reviewed Updated July 2026

Reviewed by licensed addiction specialists. Information reflects current clinical guidance.

Sources:SAMHSA·NIDA·CDC

Need immediate help? Call SAMHSA: 1-800-662-4357 (24/7, free)